---
language:
  - en
license: mit
pretty_name: Polypharmacy Combination State Coherence Profiling v0.1
dataset_name: pharma-combination-state-coherence-profiling-v0.1
tags:
  - clarusc64
  - pharma
  - polypharmacy
  - combinations
  - safety
  - coherence
task_categories:
  - tabular-regression
  - tabular-classification
size_categories:
  - n<1K
configs:
  - config_name: default
    data_files:
      - split: train
        path: data/train.csv
      - split: test
        path: data/test.csv
---

What this dataset tests

Whether a system can score multi drug combinations
by system level coherence.

The focus is:
cross system alignment
early incoherence flags
net functional shift

Required outputs

- combination_coherence_score  
- dominant_response_basin  
- cross_system_alignment_vector  
- early_incoherence_flags  
- net_functional_shift  

Use case

Early screening for combination therapies.
Find coherent combos.
Flag brittle combos before trial spend.