{ "prompts": [ { "path": "wild/6353/6353_wild_10x_wild_1_1_Image_08.jpg", "class": "wild", "explanation": [ "The cellular organization is mostly well-defined with regular distribution. Layering pattern shows normal separation with regular thickness. There is no notable absence of Purkinje cells in the expected monolayer. The granule cell layer appears thick with regular cell density. Overall structure displays continuities and no visible gaps. Staining pattern is uniform with no distinct boundaries between layers." ] }, { "path": "wild/6353/6353_wild_10x_wild_2_1_Image_11.jpg", "class": "wild", "explanation": [ "The overall cellular organization appears dense and compact. Layering pattern shows well-defined, continuous layers with consistent thickness. The Purkinje cell layer is mostly intact, observable as a monolayer. The granule cell layer is thick and densely packed, indicating high cell density. The structure appears continuous with minimal intercellular spaces. Staining pattern is homogeneous across layers." ] }, { "path": "wild/6353/6353_wild_10x_wild_2_1_Image_13.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and consistent. Layering pattern is continuous and well-defined. A monolayer of Purkinje cells is visible between the molecular and granular layers. The granule cell layer is thick and packed densely, demonstrating high cell concentration. Overall tissue structure is compact with no visible gaps. Staining pattern is uniform throughout the cerebellar cortex.", "Cellular organization is dense and uniform with well-defined layering. The Purkinje cell layer is visible and intact. The granular cell layer is thick with consistent density and regular structure. Staining exhibits a uniform pattern. This suggests a wild-type cerebellum." ] }, { "path": "wild/6353/6353_wild_10x_wild_2_3_Image_08.jpg", "class": "wild", "explanation": [ "Tissue organization shows high density as expected. Layering pattern displays slightly reduced thickness but clearly defined boundaries. Purkinje cells are clearly visible. The granule cell layer is thick with high density. Gaps and architectural discontinuities are not found. Staining pattern is uniform." ] }, { "path": "wild/6353/6353_wild_10x_wild_3_1_Image_14.jpg", "class": "wild", "explanation": [ "The image shows well defined cellular organization with high density and regular distribution of cells. The layering pattern appears distinct and normal, with negligble thinning. The Purkinje cell layer shows no depletion. The granule cell layer appears thick with high cell density. Overall, there are no visible gaps or discontinuities in the tissue architecture. The staining pattern shows uniform intensity, suggesting normal cerebellar structure." ] }, { "path": "wild/5973/5973_wild_10x_wild_1_1_Image_02.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and uniform, with compact arrangement and consistent granule cell density. The layering pattern is continuous and well-defined, indicating normal structural integrity. The Purkinje cell layer appears as a distinct monolayer. The granule cell layer is thick and densely packed, characteristic of wild-type cerebellum. The overall structure is coherent, with minimal spaces between cells. The staining pattern is homogeneous, supporting a healthy cerebellar cortex." ] }, { "path": "wild/5973/5973_wild_10x_wild_1_1_Image_10.jpg", "class": "wild", "explanation": [ "The cellular organization is well-defined with regular distribution. The layering pattern is normal with clear separation. Purkinje cells are present, indicating minimal depletion. The granule cell layer appears in regular thickness with high cell density. Overall structure shows no discontinuities, with no gaps between cells. Staining pattern is uniform, suggesting wild type control." ] }, { "path": "wild/5973/5973_wild_10x_wild_1_2_Image_16.jpg", "class": "wild", "explanation": [ "The image displays dense cellular organization with uniform distribution. The layering pattern is continuous and well-defined, maintaining consistent thickness. The Purkinje cell layer is visible as a monolayer. The granule cell layer is densely packed and thick, indicating normal cell density. Overall structure is compact with minimal intercellular gaps. Staining pattern is homogeneous, reflecting a healthy cerebellar cortex." ] }, { "path": "wild/5973/5973_wild_10x_wild_1_3_Image_07.jpg", "class": "wild", "explanation": [ "Cellular organization is well-defined with high density and regular distribution. The layering pattern displays regular thickness with clear distinction. Purkinje cells are prominent. The granule cell layer is thick with high density. There are no gaps or discontinuities in the structure. Staining shows uniformity, suggesting wild type controls." ] }, { "path": "wild/5973/5973_wild_10x_wild_2_1_Image_07.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and regular, with compact arrangement and consistent granule cell density. The layering pattern is continuous and well-defined, characteristic of normal structure. Purkinje cell layer is present as a distinct monolayer. The granule cell layer is thick and densely packed. Overall structure is coherent, with minimal spaces. Staining pattern is homogeneous, indicating healthy tissues." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_2_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization appears disrupted with uneven cell distribution. The layering pattern is not distinct and shows reduced thickness, particularly in the Purkinje cell area. Purkinje cells seem severely depleted or absent. The granule cell layer is thinner with reduced cell density. Overall structure has visible gaps and discontinuities. Staining pattern shows variable intensity and distinct boundaries between layers." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_4_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is loosely packed with low density. The layering pattern is disrupted with reduced thickness throughout. The Purkinje cell layer is absent as an intact monolayer. The granule cell layer is thinner with reduced cell density. The overall structure is disorganized with noticeable spaces between cells. Staining shows variation with clearer boundaries between layers." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_2_1_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization shows irregularity and less density. The layering pattern is abnormal with clear disruptions. Purkinje cells are largely absent, indicating severe depletion. The granule cell layer is notably thinner with lesser cell density. Overall structure is disrupted with visible gaps. Staining shows variation with clearer boundaries between layers." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_2_2_Image_02.jpg", "class": "lurcher", "explanation": [ "Cellular organization shows reduced density and irregularity. The layering pattern is discontinuous with reduced thickness. Purkinje cells are absent. The granule cell layer has low density and reduced thickness. Overall structure is disorganized with spaces between cells. Staining shows variation with clearer boundaries between layers." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_2_4_Image_02.jpg", "class": "lurcher", "explanation": [ "The image exhibits disrupted cellular organization with irregular distribution and apparent gaps in tissue architecture. The layering pattern appears abnormal with less distinction between layers and reduced thickness. There seems to be an absence or significant depletion of the Purkinje cell layer. The granule cell layer is thinned with reduced cell density. Overall structure shows discontinuities, lacking the compact and continuous organization of a wild-type section. The staining pattern is variable with more distinct boundaries between layers, indicative of Lurcher mutant pathology." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_1_Image_04.jpg", "class": "lurcher", "explanation": [ "The cellular organization appears disrupted with irregular distribution and visible gaps. The layering pattern shows abnormalities with reduced thickness and less defined layers. The Purkinje cell layer is severely depleted or absent. The granule cell layer is thinned with reduced cell density. The overall structure is less compact with architectural discontinuities. The staining pattern varies and shows distinct boundaries between the layers.", "The image shows disrupted cellular organization with irregular distribution of cells. The layering pattern appears abnormal, with clear separations and reduced thickness. There is a notable absence of Purkinje cells, indicative of degeneration. The granule cell layer appears thinned with reduced cell density. Overall, the structure demonstrates visible gaps and discontinuities, contrasting with a compact, continuous organization. The staining pattern is variable, with distinct boundaries between layers, suggesting inconsistency in staining intensity. These features align with the characteristics of Lurcher mutants.", "The cellular organization shows a less dense arrangement with irregular distribution, indicating disruption. The layering pattern appears distinct but abnormal, with reduced thickness. There is a severe depletion of Purkinje cells, as they are barely visible or absent. The granular layer is thinned with reduced cell density. The overall structure shows visible gaps and discontinuities. The staining pattern displays variable intensity with clear boundaries between layers." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_1_Image_08.jpg", "class": "lurcher", "explanation": [ "Cellular organization is irregular with less density. The layering pattern is abnormal with disruptions. The Purkinje cell layer is largely absent, indicating severe depletion. The granule cell layer is noticeably thinner with lower cell density. Overall structure shows visible gaps and disruptions. The staining pattern has variable intensity, with clearer layer boundaries, suggestive of Lurcher mutant characteristics." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_2_2_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is dense and mostly compact. The layering pattern is well-defined and continuous. The Purkinje cell layer is visible as an intact monolayer. The granule cell layer is thick and densely packed. Overall structure is compact with minimal spaces. Staining pattern is uniform and homogeneous, indicating normal cerebellar structure." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_3_1_Image_05.jpg", "class": "lurcher", "explanation": [ "The cellular organization shows irregularity with less density. Layering pattern demonstrates reduced thickness with less distinction between layers. Purkinje cells are severely depleted or absent. Granule cell layer appears thinned with reduced density. Overall structure displays discontinuities with visible gaps, and the staining pattern is variable with pronounced layer boundaries." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_3_2_Image_02.jpg", "class": "lurcher", "explanation": [ "Tissue organization appears disturbed with uneven cell distribution and structural discontinuities. Layering pattern is abnormal with reduced thickness. Purkinje cell layer is lacking, and granule cell layer is considerably thinned with reduced density. The overall architecture is disrupted and staining pattern shows variations with clear boundaries between layers." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_1_Image_05.jpg", "class": "wild", "explanation": [ "The cellular organization appears compact with a uniform distribution. Layering pattern is well-defined with consistent thickness. Purkinje cell layer is visible as a continuous monolayer. Granule cell layer is densely packed with high cell density. Overall structure is continuous with minimal spaces. Staining pattern is homogeneous." ] }, { "path": "wild/6349/6349_wild_10x_wild_2_2_Image_05.jpg", "class": "wild", "explanation": [ "There is a compact cellular organization and dense cell distribution. The layering pattern shows no separation with consistent thickness. Purkinje cell layer is visible. Granule cell layer appears thick with high cell density. No visible gaps or discontinuities are present in the structure. Staining pattern is homogeneous." ] }, { "path": "wild/6349/6349_wild_10x_wild_2_2_Image_10.jpg", "class": "wild", "explanation": [ "Cellular organization is compact and dense. The layering pattern is normal and thick. Purkine cells are prominent. The granule cell layer has high cell density. The structure is continuous with no gaps, and the staining intensity is homogeneous." ] }, { "path": "wild/6349/6349_wild_10x_wild_2_3_Image_03.jpg", "class": "wild", "explanation": [ "Cellular organization shows dense and compact arrangement. Layering patterns are well-defined and continuous. A clear Purkinje cell monolayer is observed. Granule cell layer is thick and densely packed. Overall structure remains compact with minimal gaps. Staining is consistent across layers.", "Dense cellular organization with compact arrangement is observed. The layering pattern appears normal with consistent thickness. The Purkinje cell layer is present and visible. The granule cell layer is thick and shows high cell density. The overall structure is well-organized and continuous without noticeable gaps. The staining pattern is homogeneous." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_2_Image_18.jpg", "class": "wild", "explanation": [ "Compact cellular organization with regular distribution. Continuous layer pattern with consistent thickness is noticeable. Purkinje cell layer is intact as a monolayer. The granule cell layer is thick with high cell density. No visible structural discontinuities are present and the staining pattern is homogeneous." ] }, { "path": "wild/6928/6928_wild_1_3_Image_03.jpg", "class": "wild", "explanation": [ "The cellular organization is compact with dense cell distribution. Layering pattern is well-defined with consistent thickness. Purkinje cell layer is visible as a continuous monolayer. Granule cell layer is densely packed with high cell density. Overall structure is continuous, with no visible gaps. Staining pattern is homogeneous across the cortex." ] }, { "path": "wild/6928/6928_wild_1_4_Image_12.jpg", "class": "wild", "explanation": [ "The cellular organization appears compact with dense cells and uniform distribution. Layering is well-defined, with clear separation. Purkinje cell layer is visible. Granule cell layer is densly packed. Overall structure is continuous with uniform staining intensity across the cerebellar cortex." ] }, { "path": "wild/6928/6928_wild_2_3_Image_03.jpg", "class": "wild", "explanation": [ "Cellular organization shows compact and dense arrangement. Layering patterns are well-defined and continuous. A clear Purkinje cell monolayer is present. Granule cell layer is thick and densely packed. The overall structure remains compact with minimal gaps. Staining is consistent across layers." ] }, { "path": "wild/6928/6928_wild_4_1_Image_01.jpg", "class": "wild", "explanation": [ "Compact cellular organization with regular distribution is observed. Continuous layer pattern with consistent thickness. The Purkinje cell layer is intact as a monolayer. The granule cell layer is thick with high cell density. No visible structural discontinuities and homogeneous staining pattern." ] }, { "path": "wild/6928/6928_wild_4_3_Image_06.jpg", "class": "wild", "explanation": [ "The organization is mostly compact with dense cells and uniform distribution. Layering pattern is well-defined with consistent thickness and clear separation. Purkinje cells are prominent in a monolayer. The granule cell layer is slightly thinned but densely packed. Overall structure is continuous with no gaps. Staining is homogeneous." ] }, { "path": "wild/6130/6130_wild_3_1_Image_07.jpg", "class": "wild", "explanation": [ "The image shows a compact cellular organization with dense cells and uniform distribution. The layering pattern is continuous and well-defined, with consistent thickness. The Purkinje cell layer is present and distinct. The granule cell layer is thick and densely packed with high cell density. The overall structure is continuous with no visible gaps. The staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6130/6130_wild_2_3_Image_14.jpg", "class": "wild", "explanation": [ "Cellular organization is dense with uniform distribution. The layering pattern is well-defined and continuous, with consistent thickness. There is a clear and continuous Purkinje cell layer. The granule cell layer is densely packed. The overall structure is compact, with no visible gaps. The staining pattern is homogeneous across layers." ] }, { "path": "wild/6130/6130_wild_2_1_Image_20.jpg", "class": "wild", "explanation": [ "The image shows a compact organization with dense cells and uniform distribution. The layering pattern is continuous, well-defined, and thick. The Purkinje cell layer is present and recognizable. The granule cell layer is thick and densely populated. The overall structure is uninterrupted with minimal gaps. Staining is uniform across the cortex." ] }, { "path": "wild/6130/6130_wild_2_3_Image_13.jpg", "class": "wild", "explanation": [ "Cellular organization is uniform and compact. The layering pattern is well-defined and continuous. The Purkinje cell layer is present. The granule cell layer is thick and densely packed. The overall structure is intact with no gaps. Staining is homogeneous and consistent." ] }, { "path": "wild/6130/6130_wild_2_3_Image_05.jpg", "class": "wild", "explanation": [ "The image depicts a dense and uniform cellular organization. The layering pattern is consistent and well-defined. A distinct and continuous Purkinje cell layer is present. The granule cell layer is densely packed. The overall structure shows no discontinuities, and the staining is homogeneous." ] }, { "path": "lurcher/6510/6510_lurcher_1_1_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular distribution. The layering pattern shows abnormalities, lacking clear definition between layers. Purkinje cells is absent. The granule cell layer is thinned with reduced density. Overall structure shows discontinuities. Staining intensity is variable with distinct boundaries.", "The cellular organization is disrupted with irregular distribution. The layering pattern is abnormal with reduced thickness. The Purkinje cell layer appears absent. The granule cell layer is thinner with reduced density. Overall, the structure has visible gaps and discontinuities. Staining shows variable intensity with distinct boundaries between layers." ] }, { "path": "lurcher/6510/6510_lurcher_1_2_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization appears less dense with irregular distribution. Layering is abnormal with poor separation and reduced thickness. Purkinje cells seem largely absent. The granule cell layer is thinner with fewer cells. Overall structure is discontinuous. Staining shows variable intensity and clear boundary distinctions." ] }, { "path": "lurcher/6510/6510_lurcher_2_1_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted and has reduced density with irregular distribution. Layering pattern is abnormal with reduced thickness. Purkinje cell layer is absent. Granule cell layer is thinner and loosely packed compared to a wild type cerebellum. Overall structure is discontinuous. Staining pattern is variable across the cortex." ] }, { "path": "lurcher/6510/6510_lurcher_2_2_Image_02.jpg", "class": "lurcher", "explanation": [ "Cellular organization shows disruption with irregular cell distribution. Layering is abnormal, with reduction in thickness and definition. The absence of Purkinje cells is notable. Granule cell layer is thinned and loosely packed. Overall structure presents gaps and is discontinuous. Staining intensity varies, with clear layer boundaries.", "The cells are loosely packed and disorganized. The layering pattern is disrupted. The Purkinje cell layer is absent. The granule cell layer is loosely packed and has gaps. Overall structure is discontinuous, with less compact tissue and uneven staining patterns." ] }, { "path": "lurcher/6510/6510_lurcher_3_1_Image_02.jpg", "class": "lurcher", "explanation": [ "The organization is disrupted with irregular and less dense cells. Layering pattern shows reduced thickness and poor separation. Purkinje cell layer appears markedly absent. Granule cell layer is thinned with lower density. Overall structure has visible gaps. Staining is uneven with distinct boundaries." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_1_3_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is less dense with irregular distribution, indicating disruption. The layering pattern is abnormal with poorly defined separation and reduced thickness. The Purkinje cell layer is largely absent. The granule cell layer appears thinned with fewer cells. Overall structure shows discontinuities with gaps. Staining intensity is variable with distinct boundary distinctions.", "The cellular organization shows dense arrangement, with irregular distribution suggesting less compactness. The layering pattern indicates distinct yet disrupted layers. The Purkinje cell layer appears depleted. The granule cell layer is thinned with reduced density. Overall structure features visible gaps and discontinuities, with variable staining intensity." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_2_3_Image_03.jpg", "class": "lurcher", "explanation": [ "Cellular organization shows disruption with irregular distribution. The layering pattern is abnormal with reduced thickness and unclear boundaries. The absence of the Purkinje cell layer is prominent. The granule cell layer is thinned with reduced cell density. The overall structure is discontinuous. Staining intensity is variable." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_3_4_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular cell placement. Layering exhibits reduced thickness and poor definition. The absence of Purkinje cells is noted. The granule cell layer is thinner and less dense. Overall structure has visible gaps, and staining is inconsistent." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_4_4_Image_03.jpg", "class": "lurcher", "explanation": [ "Disrupted cellular organization with uneven cell distribution. Layering pattern lacks clarity with reduced thickness and no clear separation. The Purkinje cell layer appears absent. The granule cell layer is thin and loosely packed. Staining shows variable intensity." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_5_3_Image_01.jpg", "class": "lurcher", "explanation": [ "The organization of cells is disrupted and less dense. The layering pattern is abnormal with reduced thickness. The Purkinje cell layer is notably absent. The granule cell layer is thinned and loosely packed. Staining is uneven with clear demarcations between layers." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_2_3_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization is less dense with irregular distribution. Layering pattern is abnormal with reduced thickness and poor separation. The Purkinje cells are absent, indicating disruption. The granule cell layer is thinned and loosely packed. Overall structure presents with visible gaps. Staining pattern is variable with distinct boundaries." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_2_3_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular distribution. The layering pattern shows reduced thickness and poor definition. Purkinje cell layer is absent, which is consistent with Lurcher. The granule cell layer is thinned with reduced cell density. The overall structure is discontinuous with gaps, and staining intensity varies.", "Cellular organization is disrupted. The layering pattern is non-uniform with reduced in thickness. The Purkinje cell layer is absent, and the granule cell layer is tinner and loosely packed. Overall structure is discontinuous with variable staining." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_1_1_Image_01.jpg", "class": "lurcher", "explanation": [ "The organization appears less dense with uneven cell distribution. Layering pattern is abnormal and lacks clarity. Purkinje cells are absent. The granule cell layer is thinned and loosely packed. Overall, there is a discontinuous structure with visible gaps. Staining intensity is uneven, having distinct layer boundaries." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_2_2_Image_02.jpg", "class": "lurcher", "explanation": [ "There is disrupted cellular organization with irregular distribution. The layering pattern is abnormal with unclear separation and reduced thickness. Purkinje cells appear absent in the section. The granule cell layer is thinned and has reduced density. Overall structure is discontinuous with gaps. Staining shows variable intensity." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_1_1_Image_03.jpg", "class": "lurcher", "explanation": [ "Cellular arrangement is disrupted with less dense distribution. The layering pattern is not well-defined with reduced thickness and poor separation. The Purkinje cell layer is absent, aligning with Lurcher characteristics. The granule cell layer appears thinned. Overall structure presents gaps and cohesion is poor. Staining intensity is inconsistent." ] }, { "path": "wild/6132/6132_wild_10x_wild_4_3_Image_20.jpg", "class": "wild", "explanation": [ "The image shows compact cellular organization with a continuous and well-defined layering pattern. The granule cell layer appears thick with high cell density. There is an intact Purkinje cell layer visible between molecular and granular layers. The overall structure is compact with minimal spaces between cells and homogeneous staining intensity." ] }, { "path": "wild/6133/6133_wild_2_2_Image_07.jpg", "class": "wild", "explanation": [ "The image demonstrates well-defined cellular organization with regular distribution. The layering pattern is normal, and the Purkinje cell layer can be clearly seen as a monolayer. The granule cell layer is slightly thinned but with high cell density, which is an atypical case of wild type brains. The overall structure shows compactness with no visible gaps. The staining intensity is uniform across all layers in the image. Analyzing these observations together, it is clear that this is a Wild type case." ] }, { "path": "wild/6133/6133_wild_3_1_Image_06.jpg", "class": "wild", "explanation": [ "A well-defined cellular organization is apparent with regular cell distribution. The layering pattern is normal. The Purkinje cell layer can be clearly seen as a monolayer of large cells between granule cell layer and molecular layer. The granular layer is thick and exhibits a high cell density. The overall structure is compact with no visible gaps, and the staining is uniform across different layers." ] }, { "path": "wild/6134/6134_wild_10x_wild_1_1_Image_12.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and uniform with a well-defined layering pattern. The granule cell layer is thick and densely packed. An intact monolayer of Purkinje cells is seen. The structure is continuous, and staining is homogeneous across the cortex." ] }, { "path": "wild/6134/6324_wild_1_4_Image_10.jpg", "class": "wild", "explanation": [ "Cellular organization shows compact and dense arrangement. Layering patterns are well-defined and continuous. A clear Purkinje cell monolayer is present. Granule cell layer is thick and densely packed. The overall structure remains compact with minimal gaps. Staining is consistent across layers.All these observations indicate that this is a typical wild type case." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_14.jpg", "class": "wild", "explanation": [ "The image shows well-defined cellular organization with high cell density. The layering pattern is normal. There is a prominent Purkinje cell layer as a continuous monolayer between granule cell and molecular layer, a hallmark characteristic of Wild type cases. The granular cell layer is slightly thinner but has high density, a rare case observed in Wild types. The overall structure is compact and continuous, with no gaps, and staining pattern shows homogeneous intensity across different layers. Analyzing all these observations together, it can be concluded that this is a Wild type case." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_22.jpg", "class": "wild", "explanation": [ "The image displays dense and compact cellular organization. Layers are well-defined and consistent in thickness. A clear intact monolayer of Purkinje cells is visible, indicating a normal pattern. The granular cell layer is slightly thinned but densely populated, a rare but possible case in Wild type mice. Overall tissue structure is compact and continuous with minimal spaces, and staining pattern is homogeneous across the cerebellar cortex. Analyzing thes observations, it is clear that this is a Wild type case." ] }, { "path": "wild/6353/6353_wild_10x_wild_4_2_Image_04.jpg", "class": "wild", "explanation": [ "Cellular organization appears well-defined with regular distribution and high density. There is a distinct Purkinje cell layer as a continuous monolayer between granule cell and molecular layers, typical of Wild type cases. The granular cell layer is thick with high cell density, a typical case in wild type brains. Overall structure is continuous with no noticeable gaps, and the homogeneous staining intensity can be seen across all the layers in the image. These observations indicate that this is a Wild type case." ] }, { "path": "wild/6928/6928_wild_1_2_Image_13.jpg", "class": "wild", "explanation": [ "Dense cellular organization with uniform distribution is present. Layering is continuous and consistently thick. An intact Purkinje cell layer is visible, characteristic of wild-type cerebellum. The granular layer is densely packed and thick. Overall structure is compact with minimal gaps, and staining pattern is uniform across layers." ] }, { "path": "wild/6353/6353_wild_10x_wild_1_2_Image_11.jpg", "class": "wild", "explanation": [ "Image 1 displays dense cellular organization and well-defined layering, indicative of a typical wild-type cerebellum. The Purkinje cell layer appears intact between the molecular and granular layers, with high granule cell density and consistent layer thickness. The overall structure is compact with minimal gaps, and the staining is homogeneous without stark variations." ] }, { "path": "wild/6353/6353_wild_10x_wild_2_3_Image_13.jpg", "class": "wild", "explanation": [ "Image 2 shows compact cellular organization with dense cell distribution. The Purkinje cell layer is visible, and the layering pattern is well-defined. The internal granular layer appears slightly thinner but with high cell density. The overall structure is continuous and the staining intensity is uniform." ] }, { "path": "wild/6353/6353_wild_10x_wild_3_1_Image_13.jpg", "class": "wild", "explanation": [ "Image 3 reveals compact cellular organization and well-defined layering patterns. The Purkinje layer is intact as a monolayer between granule cell layer and molecular layer. The granule cell layer is thick with high cell density, and the overall structure shows no gaps or discontinuities. The staining pattern is homogeneous." ] }, { "path": "wild/6353/6353_wild_10x_wild_3_2_Image_10.jpg", "class": "wild", "explanation": [ "In Image 4, cellular organization is compact with clear, dense layers consistent with wild-type cerebellum. The Purkinje cell layer is visible as a monolayer between molecular and granular layers. Granule cell density is high, and the layer boundaries are well-defined, with homogeneous staining throughout." ] }, { "path": "wild/6353/6353_wild_10x_wild_4_2_Image_07.jpg", "class": "wild", "explanation": [ "Image 5 exhibits compact cellular organization and well-defined layers. The Purkinje cell layer is present. The granule cell layer is thick, showing rhigh density. The overall structure is continuous and there is a uniform staining intensity with no visible gaps in structure." ] }, { "path": "wild/5973/5973_wild_10x_wild_1_1_Image_13.jpg", "class": "wild", "explanation": [ "The image shows compact cellular organization with dense and uniform layers. The Purkinje cell layer appears intact as a well-defined monolayer. The granule cell layer is thick and densely packed. There are no visible gaps or discontinuities in the overall structure. Staining is homogeneous with no stark variations." ] }, { "path": "wild/5973/5973_wild_10x_wild_2_1_Image_10.jpg", "class": "wild", "explanation": [ "This image displays well-organized cellular structure with distinct layering patterns. The Purkinje cells are visible and form a continuous layer. The granule cell layer is thick with high cell density. The overall architecture is continuous, without gaps, and staining is uniform throughout." ] }, { "path": "wild/5973/5973_wild_10x_wild_2_2_Image_17.jpg", "class": "wild", "explanation": [ "The image shows dense cellular arrangement with clear, continuous layers. Purkinje cells are present and form a intact monolayer. The granule cell layer is densely packed. Overall tissue structure is compact without observable gaps. Staining intensity is consistent across the tissue." ] }, { "path": "wild/5973/5973_wild_10x_wild_3_2_Image_12.jpg", "class": "wild", "explanation": [ "The image depicts a well-defined cellular organization with regular distribution. The monolayer of Purkinje cells is clearly visible between the Granule cell and molecular layer. The granule cell layer is thick, displaying high density. The structure is continuous and has no gaps. Staining intensity is uniform across different layers." ] }, { "path": "wild/5973/5973_wild_10x_wild_4_2_Image_09.jpg", "class": "wild", "explanation": [ "The image reflects compact and dense cellular organization with well-defined layers. Purkinje cells form an unbroken monolayer. The granule cell layer is thick with high density. The overall structure is continuous, with consistent staining intensity throughout." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_1_Image_06.jpg", "class": "lurcher", "explanation": [ "The image shows a disrupted cellular organization with irregular distribution. Layering pattern appears disrupted with variability in thickness. The Purkinje cell layer is either severely depleted or absent. The granule cell layer is thinned with reduced cell density. Overall structure shows visible gaps and discontinuities. Staining pattern is variable with distinct boundaries between layers." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_3_Image_05.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular distribution. The layering pattern is somewhat well-defined but with reduced thickness.Purkinje cell layer is completely absent. Granule cell layer is thinner and loosely packed. Structure is discontinuous with some gaps. Staining pattern is varied across the tissue." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_4_Image_06.jpg", "class": "lurcher", "explanation": [ "Cell organization is disrupted with irregular cell distribution. Layering pattern shows variability with reduced thickness. The Purkinje cell layer is significantly depleted or absent. The granule cell layer appears thinned with lower density. Structure has observable discontinuities and gaps. Staining intensity varies, with noticeable boundaries." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_2_1_Image_07.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted and irregular. Layering is abnormal with reduced thickness. Purkinje cells are absent. Granule cell layer is loosely packed and thinner compared to a wild type cerebellum. Overall structure is discontinuous with visible gaps. Staining is varied throughout." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_2_2_Image_01.jpg", "class": "lurcher", "explanation": [ "Disrupted cellular organization with irregular distribution is present. Layering appears abnormal, with reduced thickness. The Purkinje cell layer is severely reduced or missing. Granule cell layer is thinner with lower density. Overall, visible gaps and discontinuities exist in the tissue. Staining pattern is variable with distinct boundaries." ] }, { "path": "lurcher/6927/6927_lurcher_10x_lurcher_1_3_Image_02.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular cell distribution. Layering pattern is abnormal with reduced thickness. Purkinje cell layer is absent. Granule cell layer appears thinned with lower density. The overall structure shows visible gaps and discontinuities. Staining pattern is variable with distinct boundaries." ] }, { "path": "lurcher/6927/6927_lurcher_10x_lurcher_3_2_Image_05.jpg", "class": "lurcher", "explanation": [ "Cellular distribution is irregular and not compact. Layering is not continuous and shows gaps. Purkinje cell layer seems to be missing entirely. Granule cell layer is thin with reduced cell density. Overall structure is fragmented with variable staining intensity and clear delineation between layers." ] }, { "path": "lurcher/6927/6927_lurcher_10x_lurcher_6_3_Image_01.jpg", "class": "lurcher", "explanation": [ "Organization is irregular, showing disrupted layering with marked variability in thickness. The Purkinje cell layer is depleted or absent. The granule cell layer is moderately thinned. Overall tissue integrity is disrupted, with noticeable spaces and non-uniform staining." ] }, { "path": "lurcher/6927/6927_lurcher_10x_lurcher_7_4_Image_05.jpg", "class": "lurcher", "explanation": [ "Cell organization is disturbed with non-uniform distribution. Layering shows irregular thickness and does not maintain continuity. The Purkinje cell layer is absent or markedly depleted. The granule cell layer is visibly thinned and less dense. Structure exhibits discontinuities and variable staining intensity." ] }, { "path": "lurcher/6927/6927_lurcher_10x_lurcher_9_4_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is not compact and shows irregular distribution. There are visible gaps in layering with reduced thickness. The Purkinje cell layer is absent, and the granule cell layer is loosely packed. The overall structure is non-continuous with varied staining patterns." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_2_Image_15.jpg", "class": "wild", "explanation": [ "The image shows a well-defined cellular organization with lhigh cell density and regular distribution. The layering pattern is normal, with no visible separation but slightly reduced thickness. The Purkinje cell layer appears prominent. Though the granule cell layer is slightly thinned, it has no notable gaps in the tissue architecture. Staining intensity is homogenous across the cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_2_2_Image_18.jpg", "class": "wild", "explanation": [ "There is dense and compact cellular arrangement, with uniform distribution. The layering pattern is well-defined and continuous between the molecular, Purkinje, and granular layers. The Purkinje cell layer is intact, forming a monolayer. The granule cell layer is thick and densely packed. Overall, the structure is continuous with minimal spaces, and staining is homogeneous across the cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_17.jpg", "class": "wild", "explanation": [ "The cellular organization is compact, with regular distribution and high density. Layering is normal, with normal thickness and no separation between layers. The Purkinje cell layer is slightly reduced but still clearly visible. The granule cell layer shows regular cell density. Staining intensity is homogenous." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_2_Image_24.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and uniform. Well-defined layering pattern with clear layers and consistent thickness. The Purkinje cell layer is intact, and the granule cell layer is packed densely. The overall structure is compact with minimal gaps, and the staining pattern is uniform and homogeneous." ] }, { "path": "wild/6349/6349_wild_10x_wild_4_3_Image_23.jpg", "class": "wild", "explanation": [ "The cellular organization is regular, with high cell density and regular distribution. Normal layering pattern but with reduced thickness. The Purkinje cell layer is present and the granule cell layer is thinned, but with high packing density typical in a wild type control. Staining shows uniform and homogenous intensity.", "Compact organization with dense cell distribution. Layer pattern is continuous with consistent thickness. Purkinje cell layer appears intact. Granule cell layer shows some thinning but with high density. Tissue structure is continuous with no gaps. Homogeneous staining intensity can be seen through out the cerebellar cortex." ] }, { "path": "wild/6130/6130_wild_4_2_Image_20.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with a compact arrangement. Layering is well-defined and continuous. The presence of a prominent Purkinje cell layer is noticeable. The granule cell layer appears thick and densely packed. The overall tissue structure is continuous with minimal spaces, and staining is homogeneous across the cortex." ] }, { "path": "wild/6130/6130_wild_4_2_Image_14.jpg", "class": "wild", "explanation": [ "Cellular organization shows a compact arrangement with uniform distribution. The layering pattern is well-defined with consistent thickness. There is an intact Purkinje cell layer forming a visible monolayer. The granule cell layer is thick and densely packed, demonstrating a uniform structure. Staining is homogeneous, indicating a wild-type pattern." ] }, { "path": "wild/6130/6130_wild_1_1_Image_02.jpg", "class": "wild", "explanation": [ "Cellular organization is dense with regular distribution. Layers are intact and well-defined. The Purkinje cell layer is clearly visible as a monolayer between granule cell and molecular layers. The granule cell layer is thick with high density. The overall structure is continuous, and the staining pattern is uniform and consistent across different layers." ] }, { "path": "wild/6130/6130_wild_2_1_Image_01.jpg", "class": "wild", "explanation": [ "There is a dense and compact cellular organization with regular distribution. The layering is continuous and well-defined. The presence of the Purkinje cell layer appears clear and intact. The granule cell layer is thick and shows high cell density. The structure is homogeneous with even staining across the tissue, indicating a normal cerebellum." ] }, { "path": "wild/6130/6130_wild_1_1_Image_09.jpg", "class": "wild", "explanation": [ "The image displays a compact cellular organization with no visible gaps. Layering appears well-defined, with consistent thickness. The Purkinje cell layer is clearly visible as a monolayer, and the granular layer is thick and dense, consistent with the baseline observed in wild type. There is a uniform staining intensity across all the cell layers." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_3_1_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is less dense with irregular distribution. The layering pattern is distinct but abnormal. There is a near-absence of the Purkinje cell layer. The granule cell layer appears thinner with lower cell density. Overall structure shows gaps and disruptions in tissue architecture with non-uniform staining." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_4_1_Image_01.jpg", "class": "lurcher", "explanation": [ "This image shows a disrupted organization with irregular distribution. Layers are diffuse and discontinuous. The Purkinje cell layer is absent indicating neuro-degeneration. The granule cell layer is thin with lower density. Overall structure features visible gaps and discontinuities, with variable staining intensity." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_4_3_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted, less dense, with irregular distribution. Layering pattern shows separation, reduced thickness. Purkinje cell layer is either absent or severely depleted. Granule cell layer is thinned, with reduced cell density. Structure includes visible gaps and discontinuities, with variable staining." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_5_2_Image_03.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular distribution. Layering is distinct but thinner than normal. Purkinje cell layer is depleted or absent. Granule cell layer shows reduced thickness and density. Structural gaps and discontinuities are evident, with varied staining patterns." ] }, { "path": "lurcher/5954/5954_lurcher_2_2_Image_10.jpg", "class": "lurcher", "explanation": [ "The image shows disrupted cellular organization with irregular distribution. The layering pattern is abnormal and diffuse. There is an absence of a distinct Purkinje cell layer. The granule cell layer appears thinned and less dense. Overall structure exhibits gaps and discontinuities. Staining pattern is variable and non-uniform across the tissue." ] }, { "path": "lurcher/5954/5954_lurcher_2_2_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization is less dense and irregular. Abnormal and disrupted layering pattern observed. Near absence of the Purkinje cell layer. The granule cell layer is thin with low cell density. The image shows gaps and discontinuities in structure. Staining is non-homogeneous with varied intensity." ] }, { "path": "lurcher/5954/5954_lurcher_1_1_Image_06.jpg", "class": "lurcher", "explanation": [ "The image displays disrupted cellular organization with irregular distribution. Layers appear diffuse and discontinuous. The Purkinje cell layer is absent. The granule cell layer is thinned and less dense. Structural gaps and discontinuities are evident. Staining intensity is variable and non-uniform." ] }, { "path": "lurcher/5954/5954_lurcher_2_1_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is less dense with irregular distribution. Layering pattern is distinct but reduced in thickness. Purkinje cell layer seems absent or severely depleted. The granule cell layer is thinned with reduced density. Overall structure shows gaps, discontinuities. Staining is varied." ] }, { "path": "lurcher/5954/5954_lurcher_1_3_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular distribution. Layering pattern is abnormal and non-continuous. Absence of a clear Purkinje cell layer. Granule cell layer is thinned with reduced density. Overall structure shows visible gaps in architecture. Staining pattern is variable and non-uniform." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_1_Image_10.jpg", "class": "wild", "explanation": [ "The image shows uniform cellular organization with regular and dense cell distribution. The layering pattern appears distinct and abnormal with rregular thickness. The Purkinje cell layer is visible, indicating minimal loss of these cells. The granule cell layer is thick and shows high cell density. Overall, the structure reveals no visible gaps and discontinuities, with homogeneous staining intensity. These features are characteristic of a Wild type cerebellum." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_2_Image_03.jpg", "class": "wild", "explanation": [ "The tissue displays regular cellular organization with no noticeable gaps. The Purkinje cell layer is visible. Though the granule cell layer is notably thinned, the overall structure is continuous, and the staining pattern is homogenous. These observations suggest the Wild type phenotype." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_07.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with uniform distribution. Layering patterns are well-defined and continuous with consistent thickness. The Purkinje cell layer is intact, forming a monolayer between the molecular and granular layers. The granule cell layer appears thick and densely packed. The overall structure is compact, and the staining pattern is homogeneous across the cortex. These features are indicative of a Wild Type cerebellum." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_20.jpg", "class": "wild", "explanation": [ "The image shows compact cellular organization with well-defined, continuous layering. There is a clear presence of the Purkinje cell layer as an intact monolayer. The granule cell layer is dense and thick. The overall structure is tightly organized, and the staining is homogeneous and evenly distributed. These characteristics align with the Wild Type cerebellum." ] }, { "path": "wild/6349/6349_wild_10x_wild_4_2_Image_03.jpg", "class": "wild", "explanation": [ "Cellular organization appears uniform, with regular distribution and visible spaces. Layering is distinct. The Purkinje cell layer is visible. The granule cell layer is thinned but with high cell density. The overall structure is compact and well organized, with uniform staining intensity. This pattern is typical of a Wild type cerebellum." ] }, { "path": "wild/6132/6132_wild_10x_wild_1_1_Image_02.jpg", "class": "wild", "explanation": [ "The image displays uniform cellular organization with dense and compact cell distribution. The layering pattern is well-defined and continuous. The Purkinje cell layer is intact, forming a distinct monolayer. The granule cell layer is thick and shows high cell density. The overall structure is compact, and the staining pattern is homogeneous across the cortex. Class: wild." ] }, { "path": "wild/6132/6132_wild_10x_wild_1_2_Image_03.jpg", "class": "wild", "explanation": [ "The cellular organization is uniform with dense cell packing. The layering pattern is well-defined, with clear boundaries. The Purkinje cell layer is visible and intact. The granule cell layer shows a high density of cells. The overall structure maintains continuity and even staining intensity. These features are indicative of Wild Type phenotype. Class: wild." ] }, { "path": "wild/6132/6132_wild_10x_wild_1_3_Image_17.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and compact with regular distribution. Layering is well-defined with consistent thickness. The Purkinje cell layer is intact and distinct. The granule cell layer is thick and densely packed. Overall structure is compact with uniform staining. These characteristics are typical of a Wild Type cerebellum. Class: wild." ] }, { "path": "wild/6132/6132_wild_10x_wild_2_1_Image_14.jpg", "class": "wild", "explanation": [ "The image shows dense cellular organization with a well-defined, consistent layering pattern. Purkinje cell layer is intact, forming a continuous monolayer. Granule cell layer is thick and densely packed. The overall structure is compact with homogeneous staining. These features align with the Wild Type phenotype. Class: wild." ] }, { "path": "wild/6132/6132_wild_10x_wild_2_2_Image_14.jpg", "class": "wild", "explanation": [ "Cellular organization is consistent, with compact and dense cell distribution. Layering is clearly defined, showing continuity. The Purkinje cell layer forms a distinct monolayer. Granule cell layer is thick with high cell density. Overall structure is intact and compact, with homogeneous staining across the cortex. Class: wild." ] }, { "path": "wild/6130/6130_wild_4_2_Image_18.jpg", "class": "wild", "explanation": [ "The cellular organization is intact with regular distribution. The layering pattern is well defined, with thick layers. The Purkinje cell layer is clearly visible as a monolayer of Purkinje cells between the molecular and granule cell layers. The granule cell layer is dense and thick. Overall structure has uniform stainity intensity and shows no discontinuities." ] }, { "path": "wild/6130/6130_wild_4_2_Image_04.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact, with regular distribution. The layering pattern is well-defined, showing consistent thickness. The Purkinje cell layer is visible and intact. The granule cell layer is thick and densely packed. Overall structure is continuous with homogeneous staining." ] }, { "path": "wild/6130/6130_wild_2_3_Image_16.jpg", "class": "wild", "explanation": [ "The cellular organization is uniform and compact, with clear and continuous layering patterns. The Purkinje cell layer is intact and forms a monolayer. The granule cell layer is dense and thick. The overall structure is compact with even staining." ] }, { "path": "wild/6130/6130_wild_4_2_Image_01.jpg", "class": "wild", "explanation": [ "Cellular organization is regular and compact. The layering pattern is well-defined with distinct boundaries. The Purkinje cell layer is visible. The granule cell layer is thick, showing high cell density. Overall structure is continuous and homogeneous in staining." ] }, { "path": "wild/6130/6130_wild_4_1_Image_18.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with clear, continuous layers. The Purkinje cell layer is present and forms a distinct monolayer. The granule cell layer is thick and densely packed. The overall structure is compact, showing uniform staining." ] }, { "path": "lurcher/6510/6510_lurcher_1_2_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular distribution and visible gaps. The layering pattern is atypical, with less definition and reduced thickness. There appears to be a depletion of Purkinje cells, contributing to the visible disorganization. The granule cell layer is thinner and shows reduced cell density. Overall structure is discontinuous, with less compact tissue and uneven staining patterns." ] }, { "path": "lurcher/6510/6510_lurcher_1_3_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular distribution. The layering pattern is atypical, with less definition and reduced thickness. There appears to be a heavy depletion of Purkinje cells, contributing to the absence of the Purkinje layer. The granule cell layer is thinner and shows reduced cell density. Overall structure is discontinuous, with less compact tissue and uneven staining patterns.", "Cellular organization is uneven with disrupted distribution patterns. Layering appears reduced and irregular. There is an absence of a clear Purkinje cell layer. The granule cell layer is noticeably thinner and less dense than expected. The overall structure is discontinuous with visible gaps. Staining intensity is inconsistent across layers." ] }, { "path": "lurcher/6510/6510_lurcher_2_2_Image_05.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular cell distribution and visible spaces. Layering is less defined and abnormal, with reduced thickness. Purkinje cells appear severely depleted or absent. The granule cell layer shows significant thinning with reduced cell density. The overall structure is discontinuous, with variable staining intensity and distinct boundaries between layers." ] }, { "path": "lurcher/6510/6510_lurcher_3_2_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular distribution and visible gaps. The layering pattern is atypical, with less definition and reduced thickness. There appears to be a depletion of Purkinje cells, contributing to the visible disorganization. The granule cell layer is thinner and shows reduced cell density. Overall structure is discontinuous, with less compact tissue and uneven staining patterns." ] }, { "path": "lurcher/5955/5955_lurcher_1_1_Image_06.jpg", "class": "lurcher", "explanation": [ "The image shows disrupted cellular organization with irregular distribution and visible gaps. The layering pattern is atypical with less definition. Purkinje cells appear severely depleted or absent. The granule cell layer is thinner with reduced density. Overall, the structure is discontinuous with uneven staining. These features suggest a Lurcher mutant cerebellum." ] }, { "path": "lurcher/5955/5955_lurcher_1_2_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular cell distribution and visible spaces. Layering is less defined and abnormal, with reduced thickness. Purkinje cells appear depleted or absent. The granule cell layer appears thinner. The overall structure is discontinuous with variable staining intensity, indicating a Lurcher mutant cerebellum." ] }, { "path": "lurcher/5955/5955_lurcher_2_1_Image_01.jpg", "class": "lurcher", "explanation": [ "The image shows lower dense and disrupted cellular organization with irregular distribution. Layering pattern is less-defined and abnormal. The Purkinje cell layer is absent. The granule cell layer is thinner and loosely packed. Overall, the structure is discontinous with variable staining, indicative of a Lurcher mutant cerebellum." ] }, { "path": "lurcher/5955/5955_lurcher_2_2_Image_04.jpg", "class": "lurcher", "explanation": [ "The image shows lower dense and disrupted cellular organization with irregular distribution. Layering pattern is less-defined and abnormal. The Purkinje cell layer is absent. The granule cell layer is thinner and loosely packed. Overall, the structure is discontinous with variable staining, indicative of a Lurcher mutant cerebellum." ] }, { "path": "lurcher/5955/5955_lurcher_3_2_Image_01.jpg", "class": "lurcher", "explanation": [ "The image shows lower dense and disrupted cellular organization with irregular distribution. Layering pattern is less-defined and abnormal. The Purkinje cell layer is absent. The granule cell layer is thinner and loosely packed. Overall, the structure is discontinous with variable staining, indicative of a Lurcher mutant cerebellum." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_2_4_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular distribution and visible gaps. The layering pattern is atypical and less defined with reduced thickness. The Purkinje cell layer appears severely depleted or absent. The granule cell layer is thinner with reduced cell density. Overall structure shows discontinuity with uneven staining." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_2_3_Image_05.jpg", "class": "lurcher", "explanation": [ "The image shows disorganized cellular arrangement with irregular distribution and gaps. The layers are less defined, and the Purkinje cell layer is missing. The granule cell layer exhibits notable thinning and reduced density. The overall architecture is disrupted with variable staining intensity." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_1_3_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is irregular with visible spaces. Layering is less distinct. The Purkinje cell layer is depleted. The granule cell layer is thin and less dense. The tissue architecture is disrupted with discontinuities and uneven staining patterns." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_1_3_Image_05.jpg", "class": "lurcher", "explanation": [ "The cellular distribution is irregular with disrupted organization. Layering is undefined with reduced thickness. The Purkinje cell layer is mostly absent. The granule cell layer is thinned with less density. The overall structure is discontinuous, and staining intensity varies across the tissue." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_1_3_Image_02.jpg", "class": "lurcher", "explanation": [ "Cellular organization is irregular with visible gaps. Layering is abnormal and less defined. The Purkinje cell layer is absent, and the granule cell layer is thinned with reduced density. Discontinuities in the structure are evident, with variable staining patterns.", "The cellular arrangement is somewhat dense but shows inconsistency. The layering pattern is not entirely uniform, with variations in thickness. The Purkinje cell layer is absent, and the granule cell layer is thinned. Several discontinuities are present, and the staining pattern is non-uniform." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_1_Image_18.jpg", "class": "wild", "explanation": [ "The cellular organization appears compact with regular spacing. Layering patterns show normal separation. Purkinje cells are prominent, a hallmark of wild type controls. The granule cell layer is thick with high density. Overall structure looks compact with visible gaps. Staining intensity is homogeneous.", "The cellular organization is dense and compact with regular distribution. The layers show consistent thickness, and the Purkinje cell layer appears intact as a monolayer. The granule cell layer is thick and densely packed, indicating a high cell density. The overall structure is continuous with no visible gaps, and the staining pattern is homogeneous across layers." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_2_Image_14.jpg", "class": "wild", "explanation": [ "There is a dense and compact cellular organization with uniform distribution. Layering patterns are well-defined and continuous. The Purkinje cell layer appears intact, situated between molecular and granular layers. The granule cell layer is thick and densely packed. Overall structure is compact and continuous with minimal spaces. Staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_2_Image_20.jpg", "class": "wild", "explanation": [ "There is a dense and compact cellular organization with uniform distribution. Layering patterns are well-defined and continuous. The Purkinje cell layer appears intact, situated between molecular and granular layers. The granule cell layer is thick and densely packed. Overall structure is compact and continuous with minimal spaces. Staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6483/6483_wild_10x_wild_2_2_Image_18.jpg", "class": "wild", "explanation": [ "There is a dense and compact cellular organization with uniform distribution. Layering patterns are well-defined and continuous. The Purkinje cell layer appears intact, situated between molecular and granular layers. The granule cell layer is thick and densely packed. Overall structure is compact and continuous with minimal spaces. Staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6483/6483_wild_10x_wild_3_1_Image_16.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with uniform distribution. Layering is well-defined and continuous. The Purkinje cell layer is present and intact. The granule cell layer is thick and densely packed. The structure is compact and continuous with minimal spacing between cells. Staining is homogeneous across layers." ] }, { "path": "wild/6133/6133_wild_1_1_Image_05.jpg", "class": "wild", "explanation": [ "The image presents a dense and compact cellular organization with a uniform distribution. The layering pattern is well-defined and continuous. The Purkinje cell layer is visible and intact, positioned between the molecular and granular layers. The granule cell layer appears thick and densely packed. Overall, the structure is compact and continuous with minimal spaces between cells. The staining pattern is uniform across the cerebellar cortex." ] }, { "path": "wild/6133/6133_wild_1_2_Image_07.jpg", "class": "wild", "explanation": [ "The image shows dense cellular organization with uniform cell spacing. Layering patterns are well-defined and continuous. The Purkinje cell layer is intact and prominently situated. The granule cell layer is thick and shows high cell density. The overall structure is compact with consistent organization. Staining intensity is homogeneous throughout the tissue." ] }, { "path": "wild/6133/6133_wild_2_2_Image_01.jpg", "class": "wild", "explanation": [ "The image exhibits a dense and uniform cellular organization. Layering is distinct and continuous with clear boundaries. The Purkinje cell layer is intact between the molecular and granular layers. The granule cell layer is densely packed. The overall structure is compact and continuous. Staining is uniform across the cerebellar cortex.", "Dense, compact cellular arrangement with uniform distribution is observed. Continuous layers with consistent thickness are evident. The Purkinje cell layer is intact as a monolayer between molecular and granular layers. The thick internal granular layer shows high cell density. The tissue is compact and organized, with minimal cell gaps. Uniform staining across the cortex is observed." ] }, { "path": "wild/6133/6133_wild_3_2_Image_07.jpg", "class": "wild", "explanation": [ "The image displays dense and compact cellular organization. Layering patterns are well-defined and continuous. The Purkinje cell layer is intact and situated appropriately. The granule cell layer is thick and densely populated. Overall, the structure remains compact with minimal gaps. The staining pattern is even across the tissue." ] }, { "path": "wild/6133/6133_wild_4_1_Image_09.jpg", "class": "wild", "explanation": [ "The image shows a dense and uniform cellular organization. Layering is continuous and clearly defined. There is a well-preserved Purkinje cell layer. The granule cell layer is thick, with high cell density. The structure is continuous and compact with minimal intercellular space. Staining is homogeneous throughout the section." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_3_Image_15.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with uniform distribution. Layering is well-defined and continuous. The Purkinje cell layer appears intact and clearly situated. The granule cell layer is thick and densely packed. The overall structure is compact with minimal spaces between cells. Staining is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_16.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and uniform. The layering pattern is distinct and continuous. The Purkinje cell layer is intact and well-placed between the molecular and granule cell layers. The granule cell layer is thick and densely packed. The structure is compact and continuous with consistent arrangement. Staining pattern is even throughout the cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_3_Image_11.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and compact with uniform spacing. Layering is distinctly outlined and continuous. The Purkinje cell layer is preserved. Granule cell layer is thick, densely packed. The overall structure is compact with minimal intercellular gaps. Staining intensity is homogeneous across the section." ] }, { "path": "wild/6349/6349_wild_10x_wild_2_3_Image_26.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with uniform distribution. Layering is well-defined and continuous. The Purkinje cell layer is intact and situated appropriately. The granule cell layer is thick and densely populated. The overall structure is compact with minimal spaces. The staining pattern is uniform." ] }, { "path": "wild/6349/6349_wild_10x_wild_2_3_Image_04.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and uniform. Layering is distinct and continuous with clear boundaries. The Purkinje cell layer is intact, a hallmark of wild-type tissue. The granule cell layer is densely packed. Overall structure is compact and continuous. Staining is uniform across the cortex." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_1_2_Image_04.jpg", "class": "lurcher", "explanation": [ "The image displays disrupted cellular organization with noticeable gaps in the tissue architecture. The layering pattern is irregular, with visible separation and reduced thickness. The Purkinje cell layer appears severely depleted, suggesting absence. The granule cell layer is thinned with reduced cell density. Overall structure shows discontinuities, and the staining pattern is variable with distinct boundaries between layers." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_2_1_Image_09.jpg", "class": "lurcher", "explanation": [ "The image displays disrupted cellular organization with noticeable gaps in the tissue architecture. The layering pattern is irregular, with visible separation and reduced thickness. The Purkinje cell layer appears severely depleted, suggesting absence. The granule cell layer is thinned with reduced cell density. Overall structure shows discontinuities, and the staining pattern is variable with distinct boundaries between layers." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_2_2_Image_10.jpg", "class": "lurcher", "explanation": [ "This image shows disrupted cellular organization with irregular cell distribution. The layers are distinct but not uniform, appearing thinner. The Purkinje cell layer is largely absent or severely depleted. The granule cell layer appears thinned with a lower cell density. Structural gaps are visible, and the staining pattern has variable intensity.", "The image shows disrupted cellular organization with an irregular distribution of cells. The layering pattern is abnormal, with clear separations and reduced thickness. Purkinje cells are missing, indicating degeneration. The granule cell layer is thinned with reduced density. Overall structure shows visible gaps and discontinuities. Staining is variable, with clear boundaries between layers. These features are characteristic of Lurcher mutants. |" ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_2_3_Image_02.jpg", "class": "lurcher", "explanation": [ "The image displays disrupted cellular organization with noticeable gaps in the tissue architecture. The layering pattern is irregular, with visible separation and reduced thickness. The Purkinje cell layer appears severely depleted, suggesting absence. The granule cell layer is thinned with reduced cell density. Overall structure shows discontinuities, and the staining pattern is variable with distinct boundaries between layers." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_2_3_Image_04.jpg", "class": "lurcher", "explanation": [ "The image reveals disrupted cellular organization with irregular distribution. The layering is distinct yet reduced in thickness, with visible tissue gaps. There is a pronounced lack or absence of Purkinje cells. The granule cell layer is thinned with fewer cells. The staining pattern is variable, highlighting layer boundaries." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_1_Image_03.jpg", "class": "lurcher", "explanation": [ "Cellular organization shows irregular distribution with visible gaps. Layering pattern is disrupted, lacking uniformity and showing reduced thickness. Purkinje cells appear severely depleted or absent. Granule cell layer is thinned with reduced density. Overall structure shows discontinuities, with variable staining intensity highlighting distinct boundaries." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_3_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disorganized with visible gaps and has reduced density. Layering pattern is disrupted lacking uniformity. The Purkinje cell layer is absent. Granule cell layer is thin and loosely packed. Overall structure shows discontinuities, with variable staining intensity highlighting distinct boundaries." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_1_4_Image_04.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disorganized with visible gaps and has reduced density. Layering pattern is disrupted. Purkinje cell layer is absent. The granule cell layer is thinner and loosely populated. Staining pattern is variable across the cortex." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_2_1_Image_06.jpg", "class": "lurcher", "explanation": [ "Cellular architecture shows a disrupted pattern with visible gaps. Layering is distinct but thin and irregular. Purkinje cells appear reduced or missing. The granule cell layer is less dense and thinner. Staining pattern varies, highlighting irregular layer boundaries." ] }, { "path": "lurcher/6323/6323_lurcher_10x_lurcher_2_3_Image_06.jpg", "class": "lurcher", "explanation": [ "There is disrupted cellular organization with irregular distribution and visible gaps. The layering pattern is distinct but thin. Purkinje cells appear absent or severely reduced. Granule cell layer is thinned with fewer cells. Staining pattern shows variability with distinct layer boundaries." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_3_Image_11.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with visible gaps and reduced density. The layering pattern is irregular with thinning. The Purkinje cell layer is absent, indicating significant depletion. The granule cell layer appears thinned and less dense. Overall, the structure has discontinuities, and the staining pattern is variable, highlighting distinct boundaries." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_2_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with visible gaps and reduced density. The layering pattern is irregular with thinning. The Purkinje cell layer is absent, indicating significant depletion. The granule cell layer appears thinned and less dense. Overall, the structure has discontinuities, and the staining pattern is variable, highlighting distinct boundaries." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_2_1_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with visible gaps and reduced density. Layering pattern is irregular, appearing thinned. The Purkinje cell layer is absent or significantly depleted. The granule cell layer is less dense. Overall, the structure shows discontinuities with variable staining intensity.", "Cellular organization is disrupted, with irregular distribution of cells. The layering pattern is present but with reduced thickness. The Purkinje cell layer is completely depleted. The granule cell layer is thinner and loosely packed. Overall structure is discontinuous and has many gaps. Staining is variable across the cerebellar cortex." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_1_Image_05.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted, showing irregular distribution and visible gaps. Layering is distinct but appears thin and non-uniform. The Purkinje cell layer appears severely reduced or absent. The granule cell layer is thinned. Staining pattern is variable, highlighting irregular layer boundaries." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_2_2_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with noticeable gaps. Layering is thin and irregular. The Purkinje cell layer appears absent or severely depleted. The granule cell layer is thin with reduced cell density. Structure shows discontinuities with variable staining intensity." ] }, { "path": "wild/6130/6130_wild_1_2_Image_17.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and compact, with a uniform distribution. Layers are well-defined with consistent thickness. A clearly defined monolayer of Purkinje cells exists between the molecular and granular layers. The granule cell layer is thick and densely packed with high cell density. Overall structure is compact with minimal spaces between cells. Staining intensity is homogeneous across the cerebellar cortex.", "The cellular organization is dense with uniform distribution. Layering pattern displays well-defined, continuous layers. Purkinje cell layer presence is visible, indicating an intact monolayer. The granule cell layer is thick and densely packed. Overall structure is compact with minimal spaces. Staining pattern shows homogeneous intensity." ] }, { "path": "wild/6130/6130_wild_2_2_Image_06.jpg", "class": "wild", "explanation": [ "Cellular organization is uniform, with dense and regular cell distribution. Layering shows normal patterns with regular thickness. Purkinje cell layer is clearly visible. The granule cell layer is thick and has high cell density. Overall structure is compact and uniform. Staining intensity is uniform across the cerebellar cortex." ] }, { "path": "wild/6130/6130_wild_2_2_Image_11.jpg", "class": "wild", "explanation": [ "Cellular organization appears tight in some regions and shows no interruptions. The layering pattern is continuous. The Purkinje cell layer is visible and continuous. The granule cell layer thickness is regular. Overall structure reveals compactness, and staining shows no variability." ] }, { "path": "wild/6130/6130_wild_2_3_Image_10.jpg", "class": "wild", "explanation": [ "The cellular arrangement is compact with clear cellular distribution. Layers are continuous but exhibit slight thinning. The Purkinje cell layer is clearly visible. The granule cell layer has high density similar to a typical wild type. Overall, the structure is intact with uniform staining, making this a wild type control.", "Cells are densely packed with uniform distribution. Layering pattern is well-defined with consistent thickness. The Purkinje cell layer is intact, maintaining a clear monolayer. Granule cell layer is thick and densely populated. The overall structure is compact with few spaces. Staining pattern is homogeneous." ] }, { "path": "wild/6130/6130_wild_3_3_Image_06.jpg", "class": "wild", "explanation": [ "Cellular organization is dense with regular distribution. Layers are distinctly well-defined across the section. Purkinje cell layer is intact, displaying a monolayer. Granule cell layer has a thick structure with dense population. The overall tissue structure is compact with no noticeable gaps. Staining intensity is homogeneous and even.", "Cellular organization appears compact with uniform distribution. Layering pattern is well-defined and continuous. The presence of a distinct Purkinje cell layer is noted. Granule cell layer is robust and densely packed. Overall, the structure is cohesive with minimal gaps. Staining pattern is even and consistent." ] }, { "path": "wild/6134/6134_wild_10x_wild_4_1_Image_08.jpg", "class": "wild", "explanation": [ "The image shows uniform cellular organization with dense, regular distribution. Layers are well-defined and consistent. The Purkinje cell layer is visible. The granule cell layer is thick with high cell density. Overall structure is compact, showing minimal spaces. Staining intensity is homogeneous across the section." ] }, { "path": "wild/6134/6134_wild_10x_wild_3_3_Image_05.jpg", "class": "wild", "explanation": [ "Cellular organization appears dense and uniformly distributed. Layering is normal, with regular thickness. A visible Purkinje cell layer is present. The granule cell layer is thick and densely populated. The overall structure is compact with a uniform staining pattern." ] }, { "path": "wild/6134/6134_wild_10x_wild_1_2_Image_05.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with clear distribution. Layers are continuous with no interruptions. The Purkinje cell layer is intact. Granule cell layer shows high density. Overall structure is compact, and staining is even across layers." ] }, { "path": "wild/6134/6134_wild_10x_wild_2_2_Image_03.jpg", "class": "wild", "explanation": [ "Cellular arrangement shows regular density and distribution. Layering is well-maintained without gaps. The Purkinje cell layer is visible and intact. The granule cell layer is thick and densely packed. The structure appears compact with uniform staining." ] }, { "path": "wild/6134/6134_wild_10x_wild_1_4_Image_04.jpg", "class": "wild", "explanation": [ "Dense cellular organization with consistent distribution. Well-defined layers, including a visible Purkinje cell layer. The granule cell layer is thick and densely populated. Overall structure is compact, and staining is uniform throughout." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_2_Image_08.jpg", "class": "lurcher", "explanation": [ "The image shows disrupted cellular organization with irregular distribution of cells. The layering pattern appears abnormal, with clear separations and reduced thickness. There is a notable absence of Purkinje cells, indicative of degeneration. The granule cell layer appears thinned with reduced cell density. Overall, the structure demonstrates visible gaps and discontinuities, contrasting with a compact, continuous organization. The staining pattern is variable, with distinct boundaries between layers, suggesting inconsistency in staining intensity. These features align with the characteristics of Lurcher mutants." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_3_Image_03.jpg", "class": "lurcher", "explanation": [ "The image features irregular cellular organization with disrupted cell distribution. The layering pattern is abnormal, showing clear separations and reduced thickness. There is a depletion or absence of the Purkinje cell layer. The granule cell layer appears thinned with reduced cell density. Overall structure reveals visible gaps and discontinuities, contrasted with a well-organized wild-type structure. The staining pattern shows variable intensity, indicating more distinct boundaries between layers. These are typical features of Lurcher mutants.", "There is disrupted cellular organization with less density and irregular distribution. The layering pattern, although distinct, appears abnormal with thinner layers. Purkinje cells are severely depleted or absent. The granular cell layer is noticeably thinned with lower cell density. Visible gaps and discontinuities are present in the tissue architecture. Staining intensity varies and clear boundaries between layers are visible." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_3_Image_04.jpg", "class": "lurcher", "explanation": [ "The image features irregular cellular organization with disrupted cell distribution. The layering pattern is abnormal, showing clear separations and reduced thickness. There is a depletion or absence of the Purkinje cell layer. The granule cell layer appears thinned with reduced cell density. Overall structure reveals visible gaps and discontinuities, contrasted with a well-organized wild-type structure. The staining pattern shows variable intensity, indicating more distinct boundaries between layers. These are typical features of Lurcher mutants." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_3_2_Image_01.jpg", "class": "lurcher", "explanation": [ "The image reveals disrupted cellular organization with an irregular distribution of cells. The layering pattern appears distinctly abnormal with clear separation and reduced thickness. There is a pronounced absence of Purkinje cells. The granule cell layer seems thinned with reduced density. Overall, the structure shows gaps and discontinuities. The staining pattern is variable, showcasing distinct boundaries between layers. These features are indicative of Lurcher mutants.", "Cellular organization is disrupted with less dense arrangement and irregular distribution. Layering appears distinct but abnormal with reduced thickness, indicating disruption. Purkinje cells are severely depleted or absent. The granular layer is thinned and shows reduced cell density. The overall structure contains visible gaps and discontinuities. Staining intensity is variable with distinct boundaries between layers.", "Cellular organization is disrupted with scattered and irregular distribution. Layering is distinct but abnormal with varying thickness. Purkinje cell layer seems severely reduced or absent. Granular cell layer is thinned with reduced cell density. Overall structure shows discontinuities and variable staining intensity, supporting a Lurcher mutant classification." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_3_3_Image_01.jpg", "class": "lurcher", "explanation": [ "The image reveals irregular cellular organization and disrupted distribution. The layering pattern appears abnormal, with clear separations and reduced thickness. The Purkinje cell layer is notably absent, suggesting degeneration. The granule cell layer is thinned with reduced density. Overall structure displays gaps and discontinuities. Staining intensity is variable, showing distinct boundaries between layers. These features indicate a Lurcher mutant cerebellum." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_3_2_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization is irregular with disrupted distribution of cells. The layering pattern is abnormal with clear separations and reduced thickness. Purkinje cells are absent, indicative of degeneration. The granule cell layer appears thinned and less dense. Overall structure has visible gaps and discontinuities. Staining pattern is variable, with distinct boundaries between layers. These are indicative of Lurcher mutants." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_1_1_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular distribution. The layering pattern is abnormal, showing clear separations and reduced thickness. There is an absence of the Purkinje cell layer. The granule cell layer is thinned and less dense. Overall structure reveals gaps and discontinuities. Staining pattern shows variability, with distinct layer boundaries. These features align with Lurcher mutants." ] }, { "path": "lurcher/6350/6350_lurcher_10x_lurcher_1_3_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization is diffused with irregular distribution. The layering pattern is disrupted. Purkinje cell layer is completely absent. Granule cell layer appears thick but has significant reduction in density and has gaps throughout the layer. Overall structure is disrupted with visible gaps. Staining pattern is varied across the cerebellar cortex. These features are typical of a Lurcher cerebellum." ] }, { "path": "wild/5973/5973_wild_10x_wild_2_2_Image_02.jpg", "class": "wild", "explanation": [ "The image shows a densely packed cellular organization, with uniform distribution typical of a Wild Type cerebellum. The layers are well-defined and continuous, with a consistent thickness. A clear monolayer of Purkinje cells is visible between the molecular and granular layers, indicating an intact Purkinje cell layer. The internal granular layer is thick and densely packed, exhibiting high cell density. The overall tissue structure appears compact and continuous, with minimal gaps. Staining intensity is homogeneous across the cerebellar cortex, characteristic of Wild Type." ] }, { "path": "wild/6130/6130_wild_2_1_Image_12.jpg", "class": "wild", "explanation": [ "The image shows a well-defined cellular organization with regular distribution of cells. The layering pattern is normal, with clear boundaries between layers. The Purkinje cell layer is intact as a monolayer between the granule cell and molecular layers, a characteristic of wild type cases. The granule cell layer appears thinner but with high cell density, which is atypical but still possible in wild type cases. Overall tissue structure is compact and doesn't contain any noticeable gaps or discontinuities. Staining intensity is uniform across all the layers. After analyzing all these observations, it can be concluded that this is a wild type case." ] }, { "path": "wild/6132/6134_wild_10x_wild_3_2_Image_04.jpg", "class": "wild", "explanation": [ "This image shows a dense and compact cellular organization with well-defined continuous layers, indicative of Wild Type. The Purkinje cell layer appears intact, forming a monolayer between molecular and granular layers. The granule cell layer is thick and densely packed, consistent with high cell density. The overall structure is compact, with minimal spaces between cells. The staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6132/6132_wild_10x_wild_4_3_Image_01.jpg", "class": "wild", "explanation": [ "The image reveals well-defined cellular organization with regular distribution and high density, characteristic of wild type mice. The Purkinje cell layer is intact and can be easily seen as a monolayer of large cells. The granular layer is thick, with high cell density consistent with the baseline in wild type mice. There are no visible gaps in tissue architecture. The staining pattern is uniform across all the layers. These observations indicate that this is a Wild type case." ] }, { "path": "wild/6132/6132_wild_10x_wild_4_1_Image_12.jpg", "class": "wild", "explanation": [ "Cellular organization is well-defined with high density and regular distribution. The Purkinje cell layer can be clearly seen as a monolayer of larger cells. The granular layer is thick with high cell density consistent with the baseline found in wild type cases. There are no noticeable gaps or discontinuities in overall structure. The staining pattern displays uniformity across all the layers. These observations indicate that this is a wild type case." ] }, { "path": "wild/6353/6353_wild_10x_wild_1_2_Image_07.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact, with a clear layering pattern. The Purkinje cell layer is present as a distinct monolayer. The granular cell layer is thick and densely packed, contributing to a continuous overall structure. The staining pattern is homogeneous, indicating a wild-type tissue." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_2_Image_03.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and compact with uniform distribution, indicating well-defined layering. The Purkinje cell layer is visible with intact cells. The granular layer is thick and densely packed, suggesting high cell density. Overall structure appears continuous with minimal spaces, and staining is homogeneous." ] }, { "path": "wild/6483/6483_wild_10x_wild_2_2_Image_07.jpg", "class": "wild", "explanation": [ "The cellular organization shows no disruption, with dense arrangement and regular distribution. Layering is well-defined. The Purkinje cell layer is intact as a monolayer between granule cell and molecular layers. The granular layer is thick with high cell density. Overall structure is intact, and staining intensity is uniform. These observations indicate that this is a Wild type case." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_3_Image_07.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and compact with uniform distribution, indicating well-defined layering. The Purkinje cell layer is visible as an intact monolayer along the border between granule cell and molecular layers. The granular layer is thick and densely packed, suggesting high cell density. Overall structure appears continuous with minimal spaces, and staining is homogeneous." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_3_Image_05.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact, with uniform layering pattern. The Purkinje cell layer appears intact. The granular layer is densely packed, with a clear and continuous structure. Overall organization is compact with minimal gaps, and staining is homogeneous across layers." ] }, { "path": "wild/6928/6928_wild_1_2_Image_06.jpg", "class": "wild", "explanation": [ "The image shows dense cellular organization with a compact appearance. The layering pattern is well-defined with visible boundaries. Purkinje cells appear to be present between the molecular and granular layers. The granule cell layer is thick with high cell density. Overall structure is continuous with minimal spaces, and staining is homogeneous." ] }, { "path": "wild/6928/6928_wild_1_3_Image_17.jpg", "class": "wild", "explanation": [ "Cellular organization is compact with dense arrangement. The layering pattern is well-defined and normal. Purkinje cell layer appear prominent. The granule cell layer is thick with high cell density. Overall structure shows continuity, and the staining pattern has uniform intensity." ] }, { "path": "wild/6928/6928_wild_2_2_Image_04.jpg", "class": "wild", "explanation": [ "Cellular organization appears dense and compact. The layering pattern is clear with consistent thickness. The Purkinje cell layer seems intact. The granule cell layer is thick with high density. The overall structure is compact, and staining is homogeneous across layers." ] }, { "path": "wild/6928/6928_wild_4_3_Image_01.jpg", "class": "wild", "explanation": [ "Cellular organization shows dense, compact arrangement. The layering pattern is well-defined with consistent thickness. The Purkinje cell layer appears intact. The granule cell layer is thick and densely populated. The overall structure is continuous, and staining is uniform." ] }, { "path": "wild/6928/6928_wild_4_4_Image_04.jpg", "class": "wild", "explanation": [ "Cellular organization is dense with regular distribution. Layering pattern is well-defined and distinct with slightly reduced thickness. Purkinje cell layer is present. The granule cell layer is slightly thinned but with high cell density. Overall structure is continuous, and staining pattern shows uniform intensity." ] }, { "path": "wild/6324/6324_wild_4_1_Image_03.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with regular distribution. The layering pattern is well-defined with consistent thickness. Purkinje cell layer appears intact. The granule cell layer is thick with high density. The overall structure is continuous, and staining is uniform across layers." ] }, { "path": "wild/6324/6324_wild_3_1_Image_02.jpg", "class": "wild", "explanation": [ "The cellular organization is compact and dense. Layers exhibit clear boundaries and consistent thickness. Purkinje cells are visible. The granule cell layer is dense and well-populated. Overall structure is continuous with homogeneous staining." ] }, { "path": "wild/6324/6324_wild_1_2_Image_07.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with well-defined layering. The Purkinje cell layer appears prominent. The granule cell layer is thick with high cell density. Overall structure is continuous, and staining is uniform." ] }, { "path": "wild/6324/6324_wild_2_1_Image_07.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and regular. Layers are distinct with consistent thickness. Purkinje cell layer is visible. The granule layer is densely packed. The structure shows continuity and uniform staining." ] }, { "path": "wild/6324/6324_wild_1_4_Image_06.jpg", "class": "wild", "explanation": [ "Dense cellular organization with compact structure. Layering pattern is clear and well-defined. Purkinje cells are intact. The granule cell layer is thick and densely populated. Continuous structure with even staining." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_1_2_Image_06.jpg", "class": "lurcher", "explanation": [ "The image shows a disrupted cellular organization with an irregular cell distribution. The layering pattern is abnormal with unclear boundaries and reduced thickness. The Purkinje cell layer is nearly absent, indicating severe depletion. The internal granular layer is thin with diminished cell density. Overall, there are visible gaps and discontinuities in the tissue architecture. The staining pattern is uneven with distinct boundary variations between layers.", "The image shows irregular cellular organization with disrupted arrangement. The layering pattern is abnormal with reduced thickness. The Purkinje cell layer is not visible, indicating depletion. The granule cell layer appears thinned with lower density. The overall structure has visible gaps, and the staining pattern is uneven, indicating a Lurcher mutant cerebellum." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_2_1_Image_06.jpg", "class": "lurcher", "explanation": [ "The tissue exhibits reduced density, and disrupte cellular arrangement with a non-uniform distribution. Well-defined layers are absent, showcasing variability in thickness. The Purkinje cell layer is absent. A thin, loosely packed granular layer suggests reduced cell density. Overall, the structure is dis-continuous with gaps. The staining pattern is variable across the cerebellar cortex." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_2_2_Image_03.jpg", "class": "lurcher", "explanation": [ "The image displays reduced density and disrupted cellular organization with discontinuous layering patterns and reduced thickness. Purkinje cell layer is absent. The granular cell layer is thinner and loosely packed. The overall structure is discontinuous with visible gaps. The staining is variable." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_2_3_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization appears disrupted with gaps and irregular distribution. The layering pattern is distinct but shows abnormal boundaries and reduced thickness. Purkinje cells are largely absent. The granular layer is thinned with reduced cell density. Overall, there is discontinuity in tissue architecture, and the staining pattern shows variation in intensity.", "The tissue shows irregular cellular organization with disturbed layering pattern and reduced thickness. Purkinje cell layer is absent, and granular layer is thinned with fewer cells. Gaps are observed, and staining is inconsistent, which are features of a Lurcher mutant cerebellum." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_3_Image_08.jpg", "class": "lurcher", "explanation": [ "The image shows disrupted cellular organization with irregular cell distribution and gaps. The layering pattern is distinct but reduced in thickness. The Purkinje cell layer is barely detectable, indicating severe depletion. The granular layer appears thin with reduced cell density. Overall, tissue architecture is discontinuous, and staining intensity is variable across layers." ] }, { "path": "lurcher/6480/6480_lurcher_10x_lurcher_4_2_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is irregular and sparse, with disrupted layering patterns and visible gaps within the structure. The Purkinje cell layer is absent, contributing to a thinner granule cell layer with reduced density. There are notable discontinuities in the tissue architecture, and the staining pattern exhibits variable intensity." ] }, { "path": "lurcher/6480/6480_lurcher_10x_lurcher_3_2_Image_02.jpg", "class": "lurcher", "explanation": [ "Cellular arrangement appears disorganized with noticeable irregularities. Layering is unclear with reduced thickness. The Purkinje cell layer is depleted, and the granule cell layer is less dense and thinner. The overall structure shows discontinuity, with a variable staining pattern across the section." ] }, { "path": "lurcher/6480/6480_lurcher_10x_lurcher_1_2_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization is irregular and disrupted with gaps. The layering pattern is poorly defined and abnormally thin. Purkinje cells are not visible, leading to a sparse granule cell layer. The structure is discontinuous, and the staining intensity varies across the image." ] }, { "path": "lurcher/6480/6480_lurcher_10x_lurcher_2_2_Image_04.jpg", "class": "lurcher", "explanation": [ "The cellular organization displays some density, but irregular distribution and gaps are present. The layering pattern is not clearly demarcated and shows reduced thickness. Purkinje cells are notably reduced, and the granule cell layer is thin. The tissue structure is not continuous, and staining is uneven." ] }, { "path": "lurcher/6480/6480_lurcher_10x_lurcher_2_1_Image_02.jpg", "class": "lurcher", "explanation": [ "Cellular distribution is irregular with gaps and sparse areas. Layering pattern is indistinct and thin. There is a significant reduction in Purkinje cells, and the granule cell layer lacks density. The tissue architecture is discontinuous, with variable staining intensity." ] }, { "path": "wild/6130/6132_wild_10x_wild_4_3_Image_14.jpg", "class": "wild", "explanation": [ "The image shows dense cellular organization and well-defined layering with consistent thickness, suggesting intact structural integrity. There is a noticeable presence of a Purkinje cell layer and a densely packed granule cell layer, indicating a continuous tissue structure with minimal gaps. The staining appears homogeneous across the cerebellar cortex." ] }, { "path": "wild/6130/6130_wild_3_2_Image_18.jpg", "class": "wild", "explanation": [ "The tissue exhibits compact cellular organization without significant gaps. Layering is well defined and consistent in thickness, with an intact Purkinje cell layer visible. The granular layer is dense and well packed, and the staining is uniform with a homogeneous intensity." ] }, { "path": "wild/6130/6130_wild_3_2_Image_15.jpg", "class": "wild", "explanation": [ "There is a well-defined organization and regular cell distribution. The layering pattern appears thick and normal except for Granule cell layer which looks slightly thinned. The Purkinje cell layer is intact and can be clearly seen between the Granule cell layer and molecular layer. The granule cell layer is dense, and the overall structure shows compactness, with uniform staining intensity. All these observations indicate that this is a Wild type case." ] }, { "path": "wild/6130/6130_wild_3_2_Image_08.jpg", "class": "wild", "explanation": [ "Dense and compact cellular organization with consistent layering and well-defined boundaries. The presence of a Purkinje cell monolayer and thick, densely packed granule cell layer is evident. The overall structure is compact with homogeneous staining intensity." ] }, { "path": "wild/6133/6133_wild_2_3_Image_01.jpg", "class": "wild", "explanation": [ "The image shows dense and compact cellular organization with uniform distribution, characteristic of a Wild Type cerebellum. The layering pattern is well-defined, with clear boundaries and consistent thickness across the layers. The Purkinje cell layer is visible as a distinct monolayer between the molecular and granular layers, indicative of a healthy tissue structure. The granular cell layer appears thick and densely packed, confirming high cell density typically seen in Wild Type specimens. The overall tissue structure is compact, with minimal spaces between cells, suggesting intact and continuous morphology. The staining pattern is homogeneous, with consistent intensity across the cerebellar cortex, further supporting a Wild Type classification." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_2_Image_22.jpg", "class": "wild", "explanation": [ "The cellular organization shows dense, compact arrangement with many cells present, indicating high cell density. The layering pattern is well-defined, with continuous layers and consistent thickness, typical of healthy cerebellar layers. The Purkinje cell layer appears intact, forming a clear boundary between molecular and granular layers. The granular cell layer is thick and densely packed, supporting high granule cell density. Overall structure is compact with minimal spaces, indicating strong tissue integrity. The staining pattern is homogeneous across the cerebellar cortex, with no signs of irregular separation." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_13.jpg", "class": "wild", "explanation": [ "The cellular organization appears well-organized, with regular and dense arrangement consistent with the baseline. The Purkinje cell layer is clearly visible as an intact monolayer between the Granule cell and molecular layers. The layering pattern shows distinct, thick and normal layers. The granular cell layer appears thick with high cell density, consistent with the baseline found in Wild type. Overall structure is well-organized anc compact, indicating healthy tissue architecture. The staining pattern is uniform across different layers." ] }, { "path": "wild/6349/6349_wild_10x_wild_2_1_Image_15.jpg", "class": "wild", "explanation": [ "The cellular organization is compact with uniform distribution, suggesting healthy tissue. The layering pattern is well-defined and continuous. The Purkinje cell layer seems intact, maintaining its position between molecular and granular layers. The granular cell layer is densely packed, consistent with high granule cell density. Overall structure is compact and well-organized with minimal spaces. The staining pattern is homogeneous, indicating consistent cellular organization without significant disruption." ] }, { "path": "wild/6928/6928_wild_1_1_Image_08.jpg", "class": "wild", "explanation": [ "The image shows a dense and compact cellular organization with a well-defined layering pattern, indicating normal tissue structure. The Purkinje cell layer appears intact as a monolayer between the molecular and granular layers. The granular cell layer is thick with high cell density, consistent with Wild Type histology. Overall, the tissue structure is continuous, with minimal spaces between cells. The staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6133/6133_wild_1_3_Image_09.jpg", "class": "wild", "explanation": [ "The image shows compact cellular organization with regular distribution. The layering pattern is distinct and normal, with appropriate thickness. Notably, the Purkinje cell layer is clearly visible. The granule cell layer appears thick with high cell density. The overall structure is continuous and staining intensity is uniform." ] }, { "path": "wild/6133/6133_wild_2_1_Image_10.jpg", "class": "wild", "explanation": [ "This image features dense cellular organization, compactly distributed cells. The layered structure appears normal with consistent thickness. The Purkinje cell layer is prominent. The granule cell layer is thick with high cell density. Overall, the structure is continous and the staining intensity is homogeneous." ] }, { "path": "wild/6133/6133_wild_3_3_Image_06.jpg", "class": "wild", "explanation": [ "This image displays a compact, dense cellular arrangement, uniform distribution, and continuous layers. The Purkinje cell layer forms a continuous monolayer. The granular layer is densely packed. Overall, the structure is continuous with minimal gaps. Staining is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6133/6133_wild_4_1_Image_08.jpg", "class": "wild", "explanation": [ "The image shows a compact and dense cellular organization. The layering pattern is regular, with consistent thickness. The Purkinje cell layer is clearly visible as a monolayer. The granule cell layer is densely packed, supporting a wild type cerebellum. Overall, the structure is continuous with no gaps. Staining is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_1_Image_07.jpg", "class": "wild", "explanation": [ "The image exhibits compact and dense cellular organization with uniform distribution. Layering pattern is regular, with consistent thickness. The Purkinje cell layer is visible, appearing as a monolayer between the molecular and granular layers. The granule cell layer is thick and densely packed. The overall structure is continuous without any significant gaps. Staining is uniform across the cerebellar cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_24.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with a compact arrangement of cells. Continuous layering pattern with consistent thickness. The Purkinje cell layer is intact and visible as a monolayer. The granule cell layer is thick with high density, indicating normal population. The overall structure is highly organized with minimal spaces. Staining is evenly distributed across the cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_4_1_Image_05.jpg", "class": "wild", "explanation": [ "There is dense and regular cellular organization with compact cells. The layering pattern is consistent and normal in appearance. The Purkinje cell layer is visible and clearly defined. The granule cell layer is thick and densely populated. The tissue architecture is continuous and intact with no visible gaps. The staining intensity is uniform across the section." ] }, { "path": "wild/6349/6349_wild_10x_wild_5_1_Image_11.jpg", "class": "wild", "explanation": [ "The image shows a dense and compact cellular organization with regular distribution. There is a continuous and consistent layered structure with an intact Purkinje cell layer. The granule cell layer is densely packed, consistent with high cell density. The overall structure is continuous with no gaps, and the staining pattern is homogeneous." ] }, { "path": "wild/6324/6324_wild_4_1_Image_10.jpg", "class": "wild", "explanation": [ "The image displays dense and compact cellular organization with a uniform distribution. The layering pattern is regular, with consistent thickness. The Purkinje cell layer is visible and intact. The granule cell layer is thick and densely packed. The overall structure is continuous without gaps. Staining is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6324/6324_wild_2_2_Image_08.jpg", "class": "wild", "explanation": [ "Dense cellular organization is present with uniform distribution. Continuous and consistent layering is observed. The Purkinje cell layer is visible as a monolayer. The granule cell layer is thick and highly dense. There are no significant structural gaps, and staining across the section is even." ] }, { "path": "wild/6324/6324_wild_1_2_Image_08.jpg", "class": "wild", "explanation": [ "The cellular arrangement is dense and regular. Layering shows consistent thickness. The Purkinje cell layer is intact, observed between the molecular and granular layers. The granule cell layer is thick and continues to show high density. The overall structure is cohesive, and the staining is uniform." ] }, { "path": "wild/6324/6324_wild_2_2_Image_02.jpg", "class": "wild", "explanation": [ "Dense cellular organization with regular cell distribution is noted. The layering pattern is consistent and normal. The Purkinje cell layer is visibly present. The granule cell layer is packed and thick. The overall structure is continuous with no visible gaps. The staining is uniformly distributed." ] }, { "path": "wild/6324/6324_wild_2_2_Image_01.jpg", "class": "wild", "explanation": [ "The image shows densely packed cell bodies with uniform distribution. There is a continuous and consistent layer arrangement. The Purkinje cell layer appears intact. The granule cell layer is thick and full. The overall structure is orderly, and the staining pattern is homogeneous." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_1_2_Image_05.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted, with irregular distribution and gaps present. The layering pattern is distinct but shows abnormal continuity. The Purkinje cell layer is severely depleted, indicative of degeneration. The granule cell layer is thinned, with a noticeable reduction in density. The overall structure is fragmented with visible discontinuities. Staining pattern shows variable intensity with distinct boundaries." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_2_2_Image_07.jpg", "class": "lurcher", "explanation": [ "Cellular organization shows some irregularity with visible gaps. The layering pattern is present but not entirely consistent in thickness. There is a notable absence of the Purkinje cell layer. The granule cell layer appears thinned and less dense. The tissue exhibits discontinuities. Staining pattern reveals variable intensity." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_3_Image_03.jpg", "class": "lurcher", "explanation": [ "The arrangement of cells is somewhat dense but shows irregularity. Layering pattern is slightly disrupted, with reduction in thickness. The Purkinje cell layer is completely absent, suggesting degeneration. The granule cell layer is reduced in thickness and density. Overall structure has gaps and inconsistencies. Staining intensity is uneven." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_3_Image_06.jpg", "class": "lurcher", "explanation": [ "Cellular organization is irregular with pronounced gaps. Layering pattern is distinct but abnormal, lacking consistency. The Purkinje cell layer is notably absent. The granule cell layer is noticeably thinned with decreased density. The structure is discontinuous. Staining pattern exhibits variable intensity with clear layer boundaries." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_1_2_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is irregular with several gaps visible. Layering pattern is disrupted with reduced thickness. The Purkinje cell layer is notably absent. The granule cell layer appears thinned and less dense. The overall structure is discontinuous with variable staining intensity." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_2_1_Image_04.jpg", "class": "lurcher", "explanation": [ "Cell organization shows irregular distribution with gaps. The layering pattern is disrupted with noticeable thinning. The Purkinje cell layer is absent. The granule cell layer is reduced in terms of density. The structure appears fragmented with uneven staining." ] }, { "path": "lurcher/6481/6481_lurcher_10x_lurcher_3_1_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization is less dense and disrupted with a irregular distribution. Layering pattern is disrupted. The Purkinje cell layer is absent. The granule cell layer is loosely packed. The overall structure is discontinuous with gaps, and staining intensity is variable." ] }, { "path": "lurcher/5954/5954_lurcher_2_2_Image_01.jpg", "class": "lurcher", "explanation": [ "Cellular organization appears irregular with noticeable gaps. The layering pattern is disrupted with reduced thickness. The Purkinje cell layer is absent. The granule cell layer is thinned and less dense. Overall structure is discontinuous, with variable staining intensity." ] }, { "path": "lurcher/5954/5954_lurcher_2_1_Image_06.jpg", "class": "lurcher", "explanation": [ "The image shows disrupted cellular organization with visible discontinuities. The layering pattern is not uniform. The Purkinje cell layer is absent. Granule cell layer shows decreased density. Structure appears fragmented, and staining is uneven." ] }, { "path": "lurcher/5954/5954_lurcher_1_2_Image_06.jpg", "class": "lurcher", "explanation": [ "Cellular arrangement is irregular with gaps. Layering is disrupted with abnormal thickness. Purkinje cell layer is notably absent. Granule cell layer is less dense. The structure is fragmented with inconsistent staining." ] }, { "path": "lurcher/5954/5954_lurcher_2_1_Image_04.jpg", "class": "lurcher", "explanation": [ "The image shows irregular cellular organization and disrupted layering pattern. No visible Purkinje cell layer is seen. The granule cell layer appears thin. Overall, the tissue structure is discontinuous with varying staining intensity." ] }, { "path": "lurcher/5954/5954_lurcher_1_3_Image_02.jpg", "class": "lurcher", "explanation": [ "Cellular organization is disrupted with irregular distribution. Layering pattern shows abnormalities in consistency. The Purkinje cell layer is not present. The granule cell layer appears thin. The structure has discontinuities and variable staining intensity." ] }, { "path": "wild/5973/5973_wild_10x_wild_1_2_Image_11.jpg", "class": "wild", "explanation": [ "The cellular organization appears compacty with high density, showing regular cell distribution. The layering pattern is normal, with well-defined layers and consistent thickness. The Purkinje cell layer is clearly visible as a monolayer. The granular layer appears thick with high cell density. The overall structure is continuous with no gaps, and the staining pattern shows homogeneous intensity." ] }, { "path": "wild/5973/5973_wild_10x_wild_2_3_Image_20.jpg", "class": "wild", "explanation": [ "The tissue shows a dense, compact cellular organization with uniform distribution. Layers are well-defined and continuous with consistent thickness. A clear monolayer of Purkinje cells is visible between the molecular and granular layers. The granular cell layer is thick and densely packed. The overall structure is compact with minimal spaces between cells, and the staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/5973/5973_wild_10x_wild_3_2_Image_10.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with a compact arrangement, and the layering pattern is well-defined and continuous. The Purkinje cell layer appears intact, situated clearly between molecular and granular layers. The granular cell layer shows high cell density and thickness. The overall tissue structure is compact, and the staining pattern is homogeneous." ] }, { "path": "wild/5973/5973_wild_10x_wild_4_1_Image_02.jpg", "class": "wild", "explanation": [ "There is a uniform cellular organization with high density and regular distribution. The layering pattern is compact with no gaps. The Purkinje cell layer is intact as a monolayer between granule cell layer and molecular layer. The granular cell layer is thick with high cell density. The overall structure is continuous, and the staining pattern shows homogeneous intensity." ] }, { "path": "wild/5973/5973_wild_10x_wild_4_1_Image_11.jpg", "class": "wild", "explanation": [ "Cellular organization appears dense and compact. The layering pattern is normal, with consistent thickness. The Purkinje cell layer is intact and clearly visible. The granular cell layer is thick, indicating high density. The overall structure is continuous, and staining pattern is homogeneous in intensity." ] }, { "path": "wild/6353/6353_wild_10x_wild_3_1_Image_16.jpg", "class": "wild", "explanation": [ "The tissue shows a dense cellular arrangement with clearly defined and consistent layering. The Purkinje cell layer is intact and continuous. The granule cell layer is thick and densely packed, contributing to a robust overall structure. The staining pattern is homogeneous, supporting a wild-type classification." ] }, { "path": "wild/6353/6353_wild_10x_wild_3_3_Image_09.jpg", "class": "wild", "explanation": [ "Dense, compact cellular organization with clear, consistent layering is observed. The Purkinje cell layer is present and well-defined. The granular layer exhibits thickness and high density. Continuous structure with uniform staining confirms a normal, wild-type classification." ] }, { "path": "wild/6353/6353_wild_10x_wild_4_2_Image_06.jpg", "class": "wild", "explanation": [ "Cellular organization is compact with regular distribution. The layering pattern is distinct and continuous. The Purkinje cell layer is visible as a monolayer, and the granular cell layer is thick and densely packed. The overall structure is uniform with homogeneous staining, indicating a wild-type cerebellum." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_1_Image_09.jpg", "class": "lurcher", "explanation": [ "The cellular organization appears disrupted with an irregular distribution of cells. Layering patterns are not well-defined, and the gaps suggest discontinuous layers. The Purkinje cell layer seems absent, as there are no noticeable aligned large cell bodies. The granular cell layer is thinned, indicating reduced cell density. Overall structure shows visible gaps, with staining intensity seeming variable. These features align with Lurcher mutant pathology." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_2_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization is irregular, with visible disruption. There are discernible but abnormal layering patterns, displaying reduced thickness. The Purkinje cell layer seems depleted, lacking observable large neurons. The granular cell layer is thinner than normal with low cell density. The overall structure reveals gaps, and staining intensity shows variation, all characteristics pointing to Lurcher mutants." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_1_3_Image_02.jpg", "class": "lurcher", "explanation": [ "This image shows a disrupted cellular organization with irregular cell arrangement. Layering pattern is altered with distinct yet reduced thickness. Purkinje cell layer appears absent or severely depleted. Granular cell layer is thinned, with noticeable reduction in cell density. There are visible structural gaps, and the staining pattern is uneven, indicative of a Lurcher mutant." ] }, { "path": "lurcher/5917/5917_lurcher_10x_lurcher_3_1_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization appears disrupted with irregularities. Layering patterns are slightly defined but with reduced thickness. The Purkinje cell layer is absent. Granule cell layer is thinner and loosely packed. Overall tissue structure has a few gaps and variable staining is evident. These features indicate to a Lurcher Mutant cerebellum." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_2_1_Image_03.jpg", "class": "lurcher", "explanation": [ "Cellular organization is less dense and uneven. The layering pattern is disrupted, showing reduced thickness. The Purkinje cell layer is not identifiable, suggesting depletion. The granule cell layer is thinner with decreased cell density. The structure is discontinuous, and the staining pattern has variable intensity, pointing to a Lurcher mutant." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_2_Image_02.jpg", "class": "lurcher", "explanation": [ "The image displays disrupted cellular organization and irregular cell distribution. Layering is abnormal with a thinned granular cell layer. The Purkinje cell layer is depleted. There are structural gaps and variable staining intensity, consistent with a Lurcher mutant classification." ] }, { "path": "lurcher/6509/6509_lurcher_10x_lurcher_3_3_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization appears disrupted with irregular arrangement. Layering is altered with distinct but reduced thickness. Purkinje cell layer is missing, and the granular cell layer is thinned. The structure has discontinuities, and staining is uneven, indicative of a Lurcher mutant." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_3_Image_03.jpg", "class": "wild", "explanation": [ "The image shows some disruption in cellular organization but with mostly regular distribution. The layering pattern is well-defined defined with consistent thickness. Purkinje cell layer is intact as a monolayer between the granule cell layer and molecular layer. The granule cell layer is thick with high cell density. Overall tissue structure is continuous with no gaps. Staining intensity appears homogeneous." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_33.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and compact. Layering pattern shows well-defined, continuous layers with consistent thickness. The Purkinje cell layer is intact as a monolayer. The granule cell layer is thick and densely packed. Overall structure is compact with minimal spaces. Staining is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_4_3_Image_06.jpg", "class": "wild", "explanation": [ "Cellular organization shows a compact pattern with regular distribution. The layering pattern is uniform and thick. The Purkinje cell layer is visible. The granule cell layer is thick with high cell density. No visible discontinuities or gaps in tissue structure. Uniform staining intensity across the cerebellar cortex." ] }, { "path": "wild/6349/6349_wild_10x_wild_4_3_Image_11.jpg", "class": "wild", "explanation": [ "Dense and compact cellular organization with uniform distribution. Layering pattern appears continuous with consistent thickness. Purkinje cell layer is intact and well-defined. The granule cell layer is thick and densely packed, showing high cell density. Overall structure is continuous and compact. Staining is homogeneous across layers." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_3_Image_08.jpg", "class": "wild", "explanation": [ "The cellular organization appears compact and well-distributed. The layering pattern is consistent with well-defined layers. The Purkinje cell layer is visible, suggesting no significant loss. The granule cell layer is thick with high density. The overall structure lacks discontinuities, with uniform staining intensity throughout." ] }, { "path": "wild/6483/6483_wild_10x_wild_2_2_Image_21.jpg", "class": "wild", "explanation": [ "Cellular organization shows a compact structure with regular distribution. The layers are continuous with consistent thickness, and the Purkinje cell layer is present. The granule cell layer is thick and densely packed. The structure is intact without noticeable gaps, and staining intensity is homogeneous." ] }, { "path": "wild/6483/6483_wild_10x_wild_3_2_Image_15.jpg", "class": "wild", "explanation": [ "Cellular organization appears dense and compact, with regular distribution. The layering pattern is continuous with consistent thickness. The Purkinje cell layer appears intact. The granule cell layer is thick, densely packed, and shows high cell density. The overall structure is compact with no visible discontinuities, and staining is homogeneous." ] }, { "path": "wild/6483/6483_wild_10x_wild_4_2_Image_05.jpg", "class": "wild", "explanation": [ "Cellular organization shows a dense and compact pattern with regular distribution. The layering pattern is uniform and thick, with an intact Purkinje cell layer. The granule cell layer is thick and densely packed with high density. The structure is continuous without gaps, and staining intensity is even across layers." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_2_2_Image_01.jpg", "class": "lurcher", "explanation": [ "This image shows a disrupted cellular organization with irregular distribution. The layering pattern is abnormal and lacks continuity. The Purkinje cell layer is seemingly reduced or absent. The granule cell layer appears thin with decreased density. Overall, the structure is discontinuous with visible gaps. The staining pattern is variable with distinct boundaries between layers." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_3_1_Image_04.jpg", "class": "lurcher", "explanation": [ "There is a disrupted cellular organization with uneven distribution. The layering pattern shows disorganization and reduced thickness. The Purkinje cell layer is almost absent. The granule cell layer is thinned with decreased cell density. Overall, the structure is not compact, with visible discontinuities. Staining shows a variable pattern with sharp boundaries." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_5_1_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with reduced density. The layering pattern shows reduced thickness and gaps. The Purkinje cell layer is completely absent. The granule cell layer is thinner and is loosely packed compared to a wild type cerebellum. Overall, the structure is discontinuous with gaps. The staining pattern is variable across layers." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_7_4_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is irregular with disrupted distribution. The layering pattern is abnormal with reduced thickness. The Purkinje cell layer is depleted or absent. The granule cell layer is thin and less dense. Overall, the structure has visible discontinuities. Staining intensity is variable with marked boundaries between layers." ] }, { "path": "lurcher/6926/6926_lurcher_10x_lurcher_8_3_Image_03.jpg", "class": "lurcher", "explanation": [ "The cellular organization is fairly compact, but there are areas of irregular distribution. The layering pattern appears disrupted. The Purkinje cell layer seems significantly reduced or missing. The granule cell layer shows reduced density. Overall, there are noticeable gaps in tissue structure. The staining pattern is inconsistent with distinct layer boundaries." ] }, { "path": "lurcher/6510/6510_lurcher_2_1_Image_03.jpg", "class": "lurcher", "explanation": [ "Cellular organization is uneven with disrupted distribution patterns. Layering appears reduced and irregular. There is an absence of a clear Purkinje cell layer. The granule cell layer is noticeably thinner and less dense than expected. The overall structure is discontinuous with visible gaps. Staining intensity is inconsistent across layers." ] }, { "path": "lurcher/6510/6510_lurcher_2_2_Image_03.jpg", "class": "lurcher", "explanation": [ "There is disrupted cellular organization with irregular distribution. The layering pattern looks abnormal with reduced thickness. The Purkinje cell layer seems absent or significantly reduced. The granule cell layer shows decreased density. Overall, there are visible discontinuities in tissue structure. Staining is variable with distinct boundaries." ] }, { "path": "lurcher/6510/6510_lurcher_3_1_Image_04.jpg", "class": "lurcher", "explanation": [ "Cellular organization appears irregular with some areas of disrupted distribution. Layering shows abnormal patterns with reduced thickness. The Purkinje cell layer is not clearly visible. The granule cell layer is thinner and less dense. The overall tissue structure is not compact and with visible gaps. Variable staining intensity is present." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_2_Image_25.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact. The layering pattern is well-defined with consistent thickness. The Purkinje cell layer is visible and intact. The granule cell layer is thick and densely populated. Overall structure shows continuity and staining is homogeneous." ] }, { "path": "wild/6928/6928_wild_2_1_Image_01.jpg", "class": "wild", "explanation": [ "The image shows dense and compact cellular organization. The layering pattern is well-defined with continuous thickness. Purkinje cell layer can be clearly seen with a monolayer of large cells between the granule cell and molecular layers. The granule cell layer is thick and densely populated. Overall structure is continuous with minimal spaces, and staining pattern is homogeneous across layers." ] }, { "path": "wild/6349/6349_wild_10x_wild_4_3_Image_12.jpg", "class": "wild", "explanation": [ "Cellular organization is dense with regular distribution. The layering pattern is well-defined with consistent thickness. Purkinje cells are present, forming a distinct layer. The granule cell layer is thick and densely populated. Overall structure is continuous, and staining pattern shows uniform intensity." ] }, { "path": "wild/6132/6132_wild_10x_wild_2_2_Image_02.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with a uniform distribution. The layering pattern is well-defined with consistent thickness. The Purkinje cell layer appears intact and can be easily seen as a monolayer of cells. The granular cell layer is thick and densely populated. The overall structure is continuous, and staining is homogeneous across layers." ] }, { "path": "wild/6928/6928_wild_1_2_Image_17.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with a compact arrangement. The layering pattern is well-defined with consistent thickness. The Purkinje cell layer appears intact between molecular and granular layers. The granule cell layer is thick and densely packed. Overall structure is continuous with minimal spaces, and staining is homogeneous." ] }, { "path": "wild/6132/6132_wild_10x_wild_4_3_Image_13.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with regular distribution. The layering pattern is well-defined and distinct. The Purkinje cell layer is intact and prominent. The granule cell layer is thick with high cell density. The overall structure is continuous with minimal spaces. The staining pattern shows uniform intensity across layers." ] }, { "path": "wild/6133/6133_wild_1_3_Image_08.jpg", "class": "wild", "explanation": [ "The cellular organization appears well-defined with regular distribution. The layering pattern is distinct and the borders between Granule cell layer and molecular layer are intact. Purkinje cells are present as a monolayer between granule cell and molecular layers. The granular layer is slightly thinned but with high cell density which is an atypical case of Wild type. Overall, the tissue architecture is well organized, and the staining pattern is homogeneous in intensity. All these observations together indicate this is a Wild type case." ] }, { "path": "wild/6349/6349_wild_10x_wild_4_2_Image_08.jpg", "class": "wild", "explanation": [ "Cellular organization appears well defined with continuity and regular distribution. The layering pattern is distinct. Purkinje cells can be clearly seen as a monolayer, indicating intact Purkinje cell layer. The granule cell layer is slightly thinned but with high density which is an atypical case of Wild type. Overall structure shows good organization, and the staining pattern is homogeneous with uniform intensity. These observations together indicate that this is a Wild type case." ] }, { "path": "wild/6349/6349_wild_10x_wild_1_3_Image_04.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and regular. The layering pattern is well-defined with clear boundaries. The Purkinje cell layer is distinct as a monolayer. The granule cell layer is thick and densely populated. The overall structure is continuous with minimal spaces, and the staining pattern is homogeneous." ] }, { "path": "wild/6133/6133_wild_3_1_Image_01.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with regular distribution. The layering pattern is well-defined and distinct. The Purkinje cell layer is intact and prominent. The granule cell layer is thick with high cell density. The overall structure is continuous with minimal spaces. The staining pattern shows uniform intensity across layers." ] }, { "path": "wild/6130/6130_wild_3_2_Image_20.jpg", "class": "wild", "explanation": [ "Cellular organization appears well-defined with regular distribution. The layering pattern is distinct and shows baseline thickness. Though not clearly seen in this image, the Purkinje cells are prominent between granule cell layer and molecular layer as a monolayer of large cells. The granule cell layer is thick with hgih density consistent with the features in a Wild type case. Overall, the structure is continuous with no visible gaps. The staining pattern shows homogenity in intensity. All these observations indicate that this is a Wild type case." ] }, { "path": "wild/6132/6132_wild_10x_wild_4_3_Image_09.jpg", "class": "wild", "explanation": [ "Cellular organization appears well-defined with regular distribution. The layering pattern is well-defined, showing baseline thickness. The Purkinje cell layer can be clearly seen as a monolayer of large cells between Granule cell layer and molecular layer. The granule cell layer is thick with high cell density but it is not apparent in this image as it shows more of the molecular layer and the Purkinje layer at the border. Overall structure shows continuity and intact organization. The staining pattern is homogeneous across the tissue. All these observations indicate that this is a Wild type case." ] }, { "path": "wild/6130/6130_wild_1_2_Image_08.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with regular distribution. The layering pattern is well-defined with consistent thickness. Purkinje cells are present, forming a conspicuous layer. The granule cell layer is thick and densely populated. Overall structure is continuous, and staining pattern shows uniform intensity." ] }, { "path": "wild/6130/6130_wild_4_1_Image_15.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and compact with a regular distribution. The layering pattern is well-defined and distinct. The Purkinje cell layer is visible and intact. The granule cell layer is thick and densely populated. Overall structure shows continuity, and the staining pattern is homogeneous with uniform intensity." ] }, { "path": "wild/6349/6349_wild_10x_wild_3_1_Image_06.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and compact. The layering pattern is well-defined with consistent thickness. The Purkinje cell layer is intact and visible as a distinct monolayer. The granule cell layer is thick and densely populated. Overall structure is continuous without gaps, and staining pattern is homogeneous across layers." ] }, { "path": "lurcher/6927/6927_lurcher_10x_lurcher_1_1_Image_01.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular distribution. The layering pattern is less distinct with variability in thickness. Purkinje cells are absent or severely depleted. The granule cell layer is thin and shows significantly reduced cell density. Overall structure is discontinuous with visible gaps, and the staining pattern is variable across layers." ] }, { "path": "wild/6483/6483_wild_10x_wild_2_1_Image_08.jpg", "class": "wild", "explanation": [ "The cellular organization shows well-defined structure and regular distribution. The layering pattern is normal with clear boundaries. Purkinje cells are prominent and can be easily seen forming a monolayer between granule cell and molecular layers. The granule cell layer is thick with high cell density though it is not apparent in this image as it captures more molecular layer and Purkinje cell layer. Overall structure shows continuity with no visible gaps. The staining pattern is even with homogeneous intensity across layers." ] }, { "path": "wild/6353/6353_wild_10x_wild_2_1_Image_08.jpg", "class": "wild", "explanation": [ "The cellular organization appears well-defined with regular distribution. The layering pattern is normal with regular thickness and clear boundaries. The Purkinje cell layer is present. The granule cell layer is thick with high cell density consistent with the wild type cases. Overall, the structure is continuous with no visible gaps, and the staining pattern shows homogeneity in intensity." ] }, { "path": "wild/6483/6483_wild_10x_wild_1_2_Image_13.jpg", "class": "wild", "explanation": [ "The cellular organization is dense with uniform distribution. The layering pattern is continuous and consistent. The Purkinje cell layer is intact and clearly visible. The granule cell layer is thick and densely populated. Overall structure is compact with minimal gaps and homogeneous staining intensity. These features are consistent with wild type." ] }, { "path": "wild/6483/6483_wild_10x_wild_3_3_Image_02.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and uniform. The layering pattern is continuous with well-defined boundaries. The Purkinje cell layer is intact and clearly visible. The granule cell layer is thick with high cell density. Overall structure is compact and continuous without noticeable gaps. Staining intensity is homogeneous throughout the tissue." ] }, { "path": "wild/6132/6132_wild_10x_wild_4_3_Image_18.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and compact with regular distribution. The layering pattern is continuous with consistent thickness. Purkinje cell layer is clearly visible. The granule cell layer is thick and densely packed. Overall structure is compact with minimal spaces between cells. Staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6353/6353_wild_10x_wild_2_2_Image_02.jpg", "class": "wild", "explanation": [ "The cellular organization is well-defined with regular distribution. The layering pattern is normal and intact. Purkinje cells is clearly visible as a monolayer. The granule cell layer is thick with high cell density. The overall structure is continuous with no visible gaps. Staining pattern is uniform across different layers." ] }, { "path": "wild/6483/6483_wild_10x_wild_3_3_Image_06.jpg", "class": "wild", "explanation": [ "The cellular organization is uniform with a dense distribution. The layering pattern is continuous and regular. The Purkinje cell layer is intact, indicating normal cerebellar architecture. The granule cell layer is thick and densely packed. Overall structure is compact without visible gaps. The staining pattern is homogeneous across the tissue section." ] }, { "path": "wild/6134/6134_wild_10x_wild_1_3_Image_12.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and compact with a uniform distribution. Layering pattern is continuous with no visible gaps. Purkinje cell layer is present, indicating normal structure. Granule cell layer is thick and densely populated. Overall structure is cohesive with minimal spaces. Staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "lurcher/6510/6510_lurcher_2_1_Image_02.jpg", "class": "lurcher", "explanation": [ "The cellular organization is disrupted with irregular distribution. The layering pattern has gaps with rreduced thickness. The Purkinje cell layer is absent or minimally visible. The granule cell layer is thinner and has reduced denisty compared to the baseline in wild type. Overall structure is irregular and discontinuous with clearly visible gaps. The staining pattern is irregular and varies across the cerebellar cortex." ] }, { "path": "wild/6483/6483_wild_10x_wild_2_2_Image_05.jpg", "class": "wild", "explanation": [ "Cellular organization shows well-defined and dense arrangement. Layering pattern is normal with high thickness. Purkinje cells are prominent forming a continuous monolayer. Granule cell layer is thick with high cell density. Overall structure has no gaps or discontinuities. Staining pattern is uniform across different layers." ] }, { "path": "wild/6928/6928_wild_2_2_Image_03.jpg", "class": "wild", "explanation": [ "Cellular organization is uniform and dense with regular distribution. The layering pattern is continuous with consistent thickness. The Purkinje cell layer is clearly visible as a monolayer. The granule cell layer is thick and densely packed. Overall structure is compact with minimal gaps. Staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6130/6130_wild_2_3_Image_01.jpg", "class": "wild", "explanation": [ "The image shows dense and compact cellular organization with uniform distribution. The layering pattern is well-defined and with consistent thickness. The Purkinje cell layer is intact and visible. The granule cell layer appears thick and densely packed. Overall structure is compact with minimal spaces between cells, and the staining pattern is homogeneous across the cerebellar cortex." ] }, { "path": "wild/6132/6132_wild_10x_wild_4_3_Image_06.jpg", "class": "wild", "explanation": [ "The cellular organization is compact and dense. Layering pattern is well-defined and continuous. Purkinje cell layer is visible and intact. Granule cell layer is thick and densely packed. Overall structure is continuous with no visible gaps. Staining pattern is homogeneous with consistent intensity." ] }, { "path": "wild/6132/6132_wild_10x_wild_2_3_Image_06.jpg", "class": "wild", "explanation": [ "Cellular organization is dense and compact. Layering pattern is continuous with consistent thickness. Purkinje cell layer is visible as a monolayer. Granule cell layer is thick with high cell density. Overall structure is compact with minimal gaps. Staining pattern is homogeneous." ] }, { "path": "wild/6134/6134_wild_10x_wild_1_2_Image_16.jpg", "class": "wild", "explanation": [ "The cellular organization appears dense and compact. Layering pattern is continuous with uniform thickness. Purkinje cell layer is visible as a distinct monolayer. Granule cell layer shows high cell density and thickness. Overall structure is continuous and lacks gaps. Staining pattern is consistent across the section." ] }, { "path": "wild/6353/6353_wild_10x_wild_3_3_Image_11.jpg", "class": "wild", "explanation": [ "The cellular organization is compact with dense cell distribution. The layering pattern is well-defined and continuous. There is a visible monolayer of Purkinje cells. The granule cell layer appears thick and densely packed. The overall structure is compact with minimal spaces. Staining pattern is homogeneous." ] }, { "path": "wild/6353/6353_wild_10x_wild_2_1_Image_12.jpg", "class": "wild", "explanation": [ "The cellular organization is well-defined with regular cell distribution. Layering pattern appears normal with well definition and high thickness. Purkinje cells are clearly visible as a monolayer between granule cell and molecular layers. The granule cell layer is thick and high dense. Overall structure is continuous with no visible gaps. Staining pattern is uniform across different layers." ] }, { "path": "wild/6353/6353_wild_10x_wild_4_1_Image_14.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact. Layering pattern is continuous and well-defined. Purkinje cell layer is present as a clear monolayer. Granule cell layer is densely packed with high cell density. Overall structure is compact with no visible gaps. Staining pattern is homogeneous across the tissue." ] }, { "path": "wild/6130/6130_wild_3_3_Image_21.jpg", "class": "wild", "explanation": [ "The cellular organization is well-defined with regular cell distribution. Layering pattern appears normal with well definition and high thickness. Purkinje cells are clearly visible as a monolayer between granule cell and molecular layers. The granule cell layer is thinner but has high density, which is an atypical case of wild type. Overall structure is continuous with no visible gaps. Staining pattern is uniform across different layers." ] }, { "path": "wild/6928/6928_wild_1_2_Image_01.jpg", "class": "wild", "explanation": [ "The cellular organization is dense and compact with regular distribution. The layering pattern is well-defined and maintains consistent thickness. Purkinje cell layer is observed as a continuous monolayer. The granule cell layer is thick and densely packed. Overall structure is continuous without gaps. Staining pattern is homogeneous across layers." ] }, { "path": "wild/6353/6353_wild_10x_wild_4_1_Image_13.jpg", "class": "wild", "explanation": [ "The cellular organization appears compact with a regular distribution. The layering pattern is well-defined and continuous. A clear monolayer of Purkinje cells is visible. The granule cell layer is densely packed with high cell density. The overall structure is intact and shows minimal gaps. Staining pattern is homogeneous across the cortex." ] }, { "path": "wild/6132/6132_wild_10x_wild_3_1_Image_11.jpg", "class": "wild", "explanation": "Cellular organization appears regular with a well-defined and intact distribution. The layering pattern is normal with layer thickness consistent to the baseline in Wild type. There is a clearly visible Purkinje cell layer of large Purkinje cells between molecular and granule cell layers. The granule cell layer is thicj with high density, consistent with baseline observed in Wild type cases. Overall structure displays continuities and no visible gaps. Staining pattern is uniform with no distinct boundaries between layers." }, { "path": "wild/6928/6928_wild_3_4_Image_09.jpg", "class": "wild", "explanation": "Cellular organization is well-defined with high density and regular distribution. The Purkinje cell layer can be clearly seen as a monolayer of larger cells between the Granule cell and molecular layers. The granular layer is mostly thick with high cell density consistent with the baseline found in wild type cases. There are no noticeable gaps or discontinuities in overall structure. The staining pattern displays uniformity across all the layers. These observations confirm that this is a wild type case." } ], "Duration in minutes": 210, "caption correction count": 177 }