Total cystectomy and cutaneous uretero-ileostomy following supervoltage radiotherapy for bladder carcinoma. Cutaneous uretero-ileostomy was performed on 59 patients previously given irradiation at a dose of 6000 rads as a curative treatment. In 47 patients the urinary diversion was combined with total cystectomy. The indication for operation was residual tumour and/or subjective symptoms. It is concluded that radical surgery following super-voltage radiotherapy is possible, but implies a high lethality and severe complications. The prognosis is especially poor in patients who at the time of surgery have invasive malignant tumours. In our opinion, the operation should be done only if necessitated by severe subjective symptoms and not on the sole indication of residual tumour.


Duplication of the inferior vena cava in retrocaval ureter. A case of peroperative urodynamic investigation. A patient with partial duplication of the inferior vena cava and a retrocaval ureter was preoperatively studied by uro-cavography and renography. Peroperatively intrapelvic pressure measurements were made, and simultaneous EMG recordings were taken from the pelvis, and from the ureter proximal and distal to the retrocaval segment. The electrophysiological activity was normal with normal anterograde impulse transmission. Renal pelvic pressure and pressure increase during forced diuresis was within a normal range.


Anaesthesia for cystoscopy. A comparative study of 3 methods of intravenous anaesthesia: diazepam-fentanyl, thiomebumal and althesin. Three different methods of anaesthesia for diagnostic cystoscopy are compared in randomly divided series of 100 males each. Group I received diazepam-fentanyl supplemented with Althesin in case of therapeutic transurethral procedures. Group II had thiomebumalnatrium-N2O-O2 and group III had althesin-N2O-O2. Group I had no premedication while the two others were premedicated with morphine-scopolamine mixture. The period during and after anaesthesia was observed independently by the urologist, the anaesthetist, the nurses on the ward and by interviewing the patient the day after the cystoscopy. The anaesthetist was the only one who knew the method to be used. Diazepam-fentanyl proved to give sufficient analgesia. This combination offered the shortest and most uncomplicated period of recovery. Five patients given diazepam-fentanyl remembered the cystoscopy as being painful. All these cases could be related to insufficient coordination of anaesthesia and cystoscopy, which seems to be of major importance for this method.


Right ovarian vein syndrome. A case with pre- and peroperative electromyographic registration of ureteral activity. Electrophysiological studies of ureteral function in a patient with right ovarian vein syndrome demonstrated intermittent antiperistalsis as reflected from pre-operative endoureteral activity recordings. The antiperistalsis was related to the patient intermittent right flank pain. Per-operative EMG and pressure measurements revealed that the antiperistalsis apparently arose from the area of obstruction and caused pressure waves of higher amplitude than those seen during normal anterograde peristaltic activity. After section of the vein, exclusively anterograde peristalsis was observed, and at 3 month follow-up, the patient was free of right side colics.


Appendico-vesical fistula. A new case and a brief review of the literature. A new case of appendico-vesical fistula is submitted. After a brief review of the literature, it is concluded that these fistulas usually manifest themselves clinically in recurrent urinary infections without gastro-intestinal symptoms. The best aids in the difficult diagnosis are cystography and cystoscopy. Treatment is by appendectomy and excision of the fistular opening.


Complete sagittal septum of the bladder. A case report. A case of complete sagittal septum of the bladder, successfully treated by resection of the septum is reported. The literature of this rare malformation is reviewed and alternate surgical procedures are discussed with regards to bladder function and continence.


Renal vein renin ratio. Predictive value in renal and renovascular hypertension. Renal vein renin ratios were determined in hypertensive patients, 19 with renal artery stenosis, 7 with renal artery occlusion and 13 with unilateral renal hypoplasia. Twenty-one of these patients were treated surgically. Renal vein renin ratios of greater than or equal to 1.5 were associated with high frequency of operative success, but ratios less than 1.5 by no means excluded good surgical results.


Studies on optimal conditions in surgical suction systems.


Transovarial transmission of LaCrosse virus in Aedes triseriatus. As part of a continuing investigation on the ecology of LaCrosse virus in Wisconsin, field and laboratory studies were conducted to explore the possibility that the virus is transmitted transovarially in A. triseriatus mosquitoes. In laboratory experiments, A. triseriatus mosquitoes were infected by ingesting LaCrosse virus in defibrinated blood. LaCrosse virus was recovered from F1 eggs, larvae, and adults that originated from the infected parent mosquitoes. In a subsequent field study aimed at determining if transovarial transmission accounted for the survival of LaCrosse virus during the winter season, larvae that originated from overwintering A. triseriatus eggs were collected from a LaCrosse virus enzootic area in southwestern Wisconsin. LaCrosse virus was isolated from these larvae and from adult A. triseriatus that were reared from field-collected larvae. These findings strongly imply that A. triseriatus is the reservoir of LaCrosse virus and that transovarial transmission is the mechanism responsible for the maintenance of the virus during the winter season in the north central region of the United States.


Symbiosis and attenuation.

Symbiosis and attenuation. Parasitic protozoa and bacteria transmitted by vector insects and ticks resist destruction in the intermediate host, possibly through the possession of antigens similar to those of the host. There is no evidence that symbiotic microorganisms have evolved similar eclipsed antigens. Symbiotes are protected from destruction by the natural lytic agents in the host, because they remain for the most part inside special cells that have lost the ability to recognize the symbiotes as "nonself." Metallic ions may play an important role in attenuation through their effect on cell membranes and on the release of lytic agents. The symbiotes of insects are useful and interesting subjects for studying attenuation.


In vivo behavior of a Sindbis virus mutant isolated from persistently infected Aedes aegypti cell cultures. A mutant of the Sindbis virus SV-S was found to interfere with the regular course of infection by the wild strain of the virus SV-W in A. aegypti mosquitoes and in suckling mice. In mosquitoes, this result was manifested by a reduced titer of SV-W in the presence of SV-S and by a failure of the mosquitoes to transmit SV-W. In the brains of suckling mice, in the presence of SV-S, the growth of sc inoculated SV-W was suppressed, and as a result, the usually lethal course of infection by this virus was converted into a nonlethal one.


Neutralization of a togavirus by antivector antisera. An A. aegypti-propagated togavirus (Sindbis) is neutralized by antisera to both whole-body extracts and to salivary fluid of the vector mosquito. Virus propagated in Vero cells is not neutralized by such antisera. Neutralizing activity resides in the immune globulin fraction of sera. Sera from animals injected with adjuvant neutralized neither virus propagated in mosquitoes nor virus obtained from Vero cells. Although neutralizing titers were low, such activity may protect, to some degree, vertebrate hosts normally exposed to vector antigens.


Observations of Aedes albopictus cell cultures persistently infected with Sindbis virus.


Arbovirus infection of vertebrate and insect cell cultures, with special emphasis on Mokola, Obodhiang, and kotonkan viruses of the rabies serogroup. Multiplication of rabies serogroup viruses, Obodhiang and kotonkan (two presumptive arboviruses), was induced in vertebrate cell cultures with Singh's A. albopictus cell cultures used as "helper cells" in cocultivation experiments. Plaque formation without prior in vitro adaptation was induced in Vero cell cultures with eight rabies serogroup viruses: in all five instances by cocultivation of either infected BHK-21 or A. albopictus cells with Vero cells under agar overlay and in three of eight instances by direct plaque assay of infected mouse brain suspensions. In cross-plaque reduction neutralization tests with cloned viruses that represented human pathogens, rabies, Duvenhage, and Mokola, on the one hand, and the presumptive arboviruses Obodhiang and kotonkan, on the other hand, Mokola virus shared common antigenic components with both the nonarboviruses and the arboviruses. Biologically, Mokola virus was different from the other two human pathogens, rabies and Duvenhage, in that it multiplied in both vertebrate and invertebrate cell cultures. Mokola virus thus appears to be the biologic and serologic bridging agent.


Helical wall-free prokaryotes in insects: multiplication and pathogenicity.


Genetic studies of pathologic conditions and susceptibility to infection in Biomphalaria glabrata. During studies on the genetics of variation in susceptibility of B. galbrata to infection with S. mansoni, four types of proliferative amoebocytic accumulations have been observed. They occur in four different clonal stocks of B. glabrata, beginning as amoebocytic aggregations, namely, in the atrial cavity, pericardial cavity, periaortic space, and hemocoel between the stomach and intestine. Persistent amoebocytic accumulations involve the sinuses around the stomach, intestine, and hepatopancreas. In these snails, nests of undifferentiated cells occur in the anterior pericardial wall, which is considered to be a hemopoietic area. Crossing experiments indicate the involvement of genetic factors, possibly in combination with infectious agents.


Murine typhus Rickettsiae in the Oriental rat flea.


Neoplasms and tumor-like growths in the aquatic pulmonate snail Biomphalaria glabrata.


Histologic and cytochemical observations of the effects of Schistosoma mansoni on Biomphalaria glabrata.


Secondary daughter sporocysts of Schistosoma mansoni: their occurrence and cultivation.


Heavy metal toxicity to Biomphalaria glabrata (Mollusca: Pullmonata).


The fine structure of encapsulation in Biomphalaria glabrata.


Light and electron microscopy of the host-parasite interface and histopathology of Nassarius obsoletus infected with rediae of Himasthla quissetensis.


Orthodontics for general practitioners. Part 1. Introduction to orthodontics.


Prevalence of anodontia among Lucknow City school children.


Marginal microleakage at cementum-amalgam interface--influence of liners: an in vitro study.


Dental health education as related to prevention of dental diseases in India.


The prevention of chronic periodontal disease.


Preventive periodontics as related to restorative dentistry.


The stiff man syndrome: a psychiatric disease? Although the Stiff Man Syndrome has been traditionally viewed as a neurologic disorder, a number of recent articles have documented a pattern of familial, interpersonal, and intrapsychic stress which suggests that this disease may be, to a considerable degree, psychosomatic in origin. The present paper reviews several recent articles and focuses on a single case study. Although the medical diagnosis was earlier confirmed, an in-depth psychiatric evaluation and extensive psychological assessment showed many psychopathological concomitants associated with the severe muscle spasm and stiffness. A follow-up after about a year of group and individual psychotherapy showed that the symptoms were still in remission, and that the patient was functioning personally and occupationally on a significantly improved level.


Pathologist's corner: biopsy--do's and don'ts.


General anesthesia and nitrous oxide sedation: history, training requirements, and Oklahoma safety record.


"Stop! think! before you ask?".

"Stop! think! before you ask?".


Prepayment and the component society.

Prepayment and the component society.


The president's message.

The president's message.


Guidelines on advertising, Oklahoma Dental Association, adopted by the House of Delegates April 26, 1975.


The big fight.

The big fight.


Independent thoughts on dental education.


A report of lesions diagnosed in the University of Oregon Dental School biopsy service 1974-75.


Peer review and you.

Peer review and you.


Past President's report.

Past President's report.


President's message.

President's message.


Communication.

Communication.


Teeth care 1776-1976.

Teeth care 1776-1976.


High blood pressure control.

High blood pressure control.


Sweepstakes announced.

Sweepstakes announced.


Dental plaque reduction with an anti-bacterial mouthrinse. Ultrastructural, microbiological and biochemical changes.


Periodontal disease information in college health education.


How reliable is the electric pulptester?


Analgesics.

Analgesics.


Fluoridation.

Fluoridation.


Your ODA: a strong voice for Ontario dentists.


Lining materials.

Lining materials.


Dental care for children in hospital.

Dental care for children in hospital.


Tetracycline staining of teeth.

Tetracycline staining of teeth.


An evaluation of the initial advanced course for school dental nurses.


Total coronal pulpotomy of the vital permanent molar.


Non-accidental injuries to children.

Non-accidental injuries to children.


X-rays and some aspects of their use in dentistry.


The development and present usage of fissure sealants.


Water fluoridation and dental caries.

Water fluoridation and dental caries.


Periodontal disease in children.

Periodontal disease in children.


Viral hepatitis.

Viral hepatitis.


Assessment of traumatised anterior teeth in children.


Planning the extraction of first permanent molars.


Dentist-patient relationship.

Dentist-patient relationship.


Shortage area student program.

Shortage area student program.


Management of child dental patients.

Management of child dental patients.


Availability and use of dental wedges.

Availability and use of dental wedges.


Survey of minority programs in dental education.


Speech. Report of a seminar. Speech as affected by dental abnormalities.


Caries-preventive mechanisms of fluoride.


Silver amalgam.

Silver amalgam.


Blame is...

Blame is...


Grandmas cove.

Grandmas cove.


Who's afraid of the R.V.I.

Who's afraid of the R.V.I.


A medical expedition to Nigeria.

A medical expedition to Nigeria.


Do's and don'ts for the doctor.

Do's and don'ts for the doctor.


A modern fairy story.

A modern fairy story.


Pure sweet and deadly.

Pure sweet and deadly.


Diabetic retinopathy.

Diabetic retinopathy.


Medical students through the eyes of a general practitioner.


Dental identification.

Dental identification.


Oh to be an A.D.O. now that spring is here.