Ageing, immune response, and mortality.

Ageing, immune response, and mortality.


Allergen-specific IgE in atopic dermatitis.


Alopecia mucinosa with neurofollicular changes.


Alpha-fetoprotein in bovine hepatocellular carcinoma.


Alpha 1-fetoprotein and carcinoembryonic antigen in a patient with carcinoid of the stomach.


Amino acid analysis with fluorescamine of stained protein bands from polyacrylamide gels.


Amino acid sequence at the haem region of cytochrome c2 from Rhodopseudomonas palustris, strain X.


An antigen in Hodgkin's disease tissue cultures: radioiodine-labeled antibody studies. An antiserum was prepared in rabbits against an antigen obtained by density gradient sedimentation of centrifuged medium from monolayer cultures of spleens involved by Hodgkin's disease. The antiserum was tested by isotopic antibody techniques with cells from each of eight cultures derived from spleens involved by Hodgkin's disease, four cultures derived from normal adult spleen, and one culture each of fetal spleen and thymus. By an indirect radioiodine-labeled antibody assay, anti-Hodgkin's disease globulin reacted with an antigen on the surface of cells from the Hodgkin's disease cultures, the quantity of which was related to the number of target cells and the amount of antibody used. This Hodgkin's disease tissue-culture antigen did not react with a rabbit antiserum against fractionated medium from a normal spleen culture, nor against noncultured Hodgkin's disease tumor tissue. The tumor specificity of the Hodgkin's disease tissue-culture antigen was assessed by a direct technique using (125)I-labeled anti-Hodgkin's disease globulin absorbed with either cultured Hodgkin's disease cells or with cultured normal cells. By this method the quantity of antigen on cells from Hodgkin's disease cultures was 15- to 30-fold greater than that on cells from normal cultures. The Hodgkin's disease tissue-culture antigen is intimately associated with the propagation of the tumor in monolayer cultures, but its identity has not been established: it could be a viral component, a tumor or fetal antigen, or a normal tissue constituent.


An arousal pattern in children with organic cerebral dysfunction.


An electronic circuit for detection of EEG seizures recorded with implanted electrodes.


An immunohistochemical study of the skin of healthy individuals.


An inexpensive device for rapid destaining of cylindrical and slab acrylamide gels.


An investigation on the chemical nature of the cuticle of a polychaete Nereis diversicolor (Annelida).


An unusual case of massive hypertrophy of the breasts.


Animal models of the asthmatic state.

Animal models of the asthmatic state.


Antenatal diagnosis and lung maturation in anencephaly.


Anorexia nervosa: a clinical, psychiatric, and laboratory study. I. Clinical and laboratory investigation.


Anti-reticulin antibodies in malabsorption syndromes.


Antibiotic concentrations in relation to structural changes in maxillary sinus mucosa following intramuscular or peroral treatment.


Antibodies recognise specific structures of triple-helical polynucleotides built on poly(A) or poly(dA).


Antibodies to chick-tendon procollagen. Affinity purification with the isolated disulfide-linded NH2-terminal extensions and reactivity with a component in embryonic serum.


Antibodies to DNP, DNP-glycylglycylglycine and DNP-p-aminobenzoylglutamate.


Antibody response to different determinants on carcinoembryonic antigen (CEA).


Antigen-dependent alterations in the lipid composition of the CNS in guinea pigs with experimental allergic encephalomyelitis.


Antigenic determinants in the N-terminal halves of human kappa-chains; their relation to the variable region subgroups.


Antigenic differences between the ends and shafts of sex pili.


Antigenic differences between T and B lymphocytes in man.


Antigenic expression and cross reactions in HL-A variants of lymphoid cell lines.


Argininosuccinic aciduria. Report of three cases and the effect of high and reduced protein intake on the clinical state.


Aristedes: a second century case report.


Arthur Henry Jacobs.

Arthur Henry Jacobs.


Assessment of coma and impaired consciousness. A practical scale.


Assignment of a gene for adenosine deaminase to human chromosome 20.


Association between maternal Herpesvirus infections and congenital malformations.


Association of house-dust and grass-pollen allergies with specific IgA antibody deficiency.


Auditory and visual evoked potentials during hyperoxia.


Autofluorescence of drusen of the optic nerve head.


Automated analysis of deoxyribonucleic acid, protein and nuclear to cytoplasmic relationships in tumor cells and gynecologic specimens.


Automated autoradiographic grain counting in human determined context.


Automated classification of normal and abnormal leukocytes.


Autosomal dominant insensitivity to pain with hyperplastic myelinopathy and autosomal dominant indifference to pain.


Axonal transport of adenosine and uridine derivatives and transfer to postsynaptic neurons.


B cell, T cell and monocyte origin of the guinea pig L2C leukemia, mouse lymphomas and human leukemias and lymphoblastic cell lines.


Behaviour of serum immunoglobulins during and after intravenous administration of gamma-globulins in patients with antibody deficiency syndrome.


Behaviour of some enzymes in rat kidney in acute poisoning with furfural.


Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse.


Better techniques for bagging stomas. 3. Ileostomies.


Binding capacity of (NH4)2SO4-precipitate (25 percent-65 percent) of PH 5 enzyme of rat liver, after fasting and refeeding.


Binding of dihydrostreptomycin to ribosomes from viomycin-sensitive and -resistant strains of Mycobacterium smegmatis.


Binding of thyroglobulin and thyroglobulin-antithyroglobulin immune complex to extraocular muscle membrane.


Bioassay of growth hormone, I, Determination of longitudinal bone growth with tetracycline in hypophysectomized rats.


Biochemical properties of histocompatibility antigens.


Biochemical side effects of drugs in the elderly.


Biophysical differentiation between lymphocytes from healthy donors, patients with malignant diseases and other disorders. Changes in the structuredness of the cytoplasmic matrix (SCM) of human lymphocytes induced by PHA, CaBP and EF were studied with the technique of fluorescence polarization. The study suggests that the SCM test may offer a new and fast technique for the detection of malignant growth.


Biosynthesis of small peptides.

Biosynthesis of small peptides.


Blood granulocyte staining with acridine orange. Changes with infection.


Blood pressure and heart rate in the rabbit during animal hypnosis.


Bowen's illumitran modified for mass-slide duplication.


Bowel transit-times in two populations experiencing similar colon-cancer risks.


Breast cancer: molecular basis for a viral etiology.


Bronchial brush biopsy in Hodgkin's disease.


Calcitonin secretion and APUD characteristics of naturally occurring medullary thyroid carcinomas in rats.


Calcium translocation by cells.

Calcium translocation by cells.


Capability of lambs to absorb immunoproteins from freeze-dried bovine colostrum.


Care after nasal surgery.

Care after nasal surgery.


Cardiology patient simulator. Development of an animated manikin to teach cardiovascular disease.


Cell structure and function in the visual cortex of the cat. 1. The organization of the visual cortex was studied with a technique that allows one to determine the physiology and morphology of individual cells. Micro-electrodes filled with the fluorescent dye Procion yellow were used to record intracellularly from cells in area 17 of the cat. The visual receptive field of each neurone was classified as simple, complex, or hypercomplex, and the cell was then stained by the iontophoretic injection of dye.2. Fifty neurones were successfully examined in this way, and their structural features were compared to the varieties of cell types seen in Golgi preparations of area 17. The majority of simple units were stellate cells, whereas the majority of complex and hypercomplex units were pyramidal cells. Several neurones belonged to less common morphological types, such as double bouquet cells. Simple cells were concentrated in layer IV, hypercomplex cells in layer II + III, and complex cells in layers II + III, V and VI.3. Electrically inexcitable cells that had high resting potentials but no impulse activity were stained and identified as glial cells. Glial cells responded to visual stimuli with slow graded depolarizations, and many of them showed a preference for a stimulus orientation similar to the optimal orientation for adjacent neurones.4. The results show that there is a clear, but not absolute correlation between the major structural and functional classes of cells in the visual cortex. This approach, linking the physiological properties of a single cell to a given morphological type, will help in furthering our understanding of the cerebral cortex.


Cell surface markers for human T and B lymphocytes.


Cell to cell transmission of virus in the central nervous system. I. Subacute sclerosing panencephalitis.


Cell-wall structure, mitosis and urease activity in Torulopsis species of high GC content.


Ceroid-like pigment in age changes of human cartilage.


Changes in canine mammary gland histology during the estrous cycle.


Changes in the activity and isozymic forms of lactic dehydrogenase in the rabbit oviduct following copulation.


Changes in immunospecificity and biologic activity of bovine insulin due to subsequent removal of the amino acids B1, B2, and B3.


Changing enzyme patterns in chick organs during development.


Characteristics of the conglutinating substance of sheep serum. The conglutinating factor in sheep serum was characterized utilizing its ability to react with sensitized erythrocytes which had been alexinated with horse complement. The conglutinating substance in sheep serum was inactivated by the action of 2-mercaptoethanol, did not require calcium ions for its activity, was not inhibited by N-acetyl-D-glucosamine or L-fucose sugars and did not react directly with zymosan. All these activities distinguish this serum factor from bovine conglutinin. These data show that the conglutinating factor in sheep serum is an immunoconglutinin. Reactivity of sheep immunoconglutinin with both heterologous and autologous complement was demonstrated.


Chronic myelomonocytic leukemia in adults.


Cinefilm and EEG recording during "hand-waving" attacks of an epileptic, photosensitive child.


Circulating immune complexes in human neuroblastoma: direct assay and role in blocking specific cellular immunity.


Clindamycin effects on experimental ocular toxoplasmosis in the rabbit.


Clinical use of narcotic analgesics in terminal cancer.


Clinico-roentgenological characteristics of pathogenesis of mandibular-joint ankylosis.


Clinical cardiovascular pharmacology of dobutamine. A selective inotropic catecholamine.


Closed prostatectomy for relief of obstruction.


Closure of the uterine lumen at implantation in senescent golden hamsters.


Color information in blood cells.

Color information in blood cells.


Collagenolytic activity in rheumatoid nodules. I. Effect on acid-soluble tropocollagen.


Comments on estimations and tests of EEG amplitude distributions.


Colored reverse-banding of human chromosomes with acridine orange following alkaline-formalin treatment: densitometric validation and applications.


Comparison of effects of glucagon and valinomycin on rat liver mitochondria and cells.


Comments on the method of analysis of the proteins from nuclear particles.


Competitive inhibition of reagin-mediated histamine release by a human IgG2 myeloma protein.


Complement-independence of tolerance induction.


Computer-assisted tomography (EMI scanner). Its place in investigation of suspected intracranial tumours.


Computer-controlled multiparameter analysis and sorting of cells and particles.


Computer-oriented analysis of human chromosomes. IV. Deoxyribonucleic acid-based centromeric index.


Computer-based electronic cell volume analysis with the AMAC II transducer.


Conglomerates of tubular structures in BCG-induced alveolar macrophages revealed by negative staining.


Considerations on the use of analgesic drugs in different stages of neoplastic diseases.


Contributions to the study of the chemical nature of the nucleolar argentophil substance.


Coronal topography of human auditory evoked responses.


Control of photosynthetic oxygen evolution by the internal pH of the chloroplast thylakoid. Inhibition of photosynthetic oxygen evolution by uncouplers at high pH and restoration of electron flow by an artificial electron donor for photosystem II.


Correction of post traumatic enophthalmos.


Cotrimoxazole in the treatment of non-gonococcal urethritis.


Critical-point drying: rapid method for the determination of bacterial extracellular polymer and surface structures. The relative amount of extracellular polymer which remains about Azotobacter vinelandii, Zoogloea ramigera, Klebsiella pneumoniae, and Diplococcus pneumoniae after critical-point drying was studied by electron microscopy. The results obtained with this technique are compared to those obtained with methods that illustrate extracellular polymer, such as freeze-etching and ruthenium red staining. Comparative results indicate critical-point drying to be a rapid, reliable method for the determination of capsule-like polymer surrounding bacterial cells. In addition, critical-point drying can be used to observe morphogenetic changes, such as vesicle production.


Cyclic AMP induced growth promotion in sunflower callus tissue.


Cytochemical and morphologic identification of macrophages and eosinophils in tissue cultures of normal human bone marrow.


Cytochemical localization of nucleic acids with gallocyanin.


Danger signals in the separation-individuation process. The observations and formulations of Margaret S. Mahler.


Dean's lecture. Immunoglobulin E and reaginic hypersensitivity.


Decarboxylation of exogenous L-5-hydroxytryptophan after destruction of the cerebral raphe system.


Demonstration of carcinoembryonic antigens (CEA), nonspecific cross-reacting antigens (NCA) and an associated alpha protein in normal human tissues and fluids by immunodiffusion techniques.


Demonstration of lymphocyte nucleoli.

Demonstration of lymphocyte nucleoli.


Deoxyribonucleic acid cytochemistry for automated cytology.


Detection of cytochrome P-450 in subcellular fractions of Endomycopsislipolytica grown on n-hexadecane.


Detection of dengue cell-surface antigens by peroxidase-labeled antibodies and immune cytolysis. The appearance of dengue-specific plasma membrane (DSPM) antigens in infected LLC-MK(2) cell cultures was studied by (51)Cr release in immune cytolysis and at an ultrastructural level using peroxidase-labeled antibodies. DSPM antigen was first detected at 36 h with electron microscopy in approximately 30% of the cells, and this percentage did not increase with time. However, both surface staining with peroxidase-labeled antibodies and (51)Cr release indicated that the amount of DSPM antigen per cell increases with time. The appearance of (51)Cr release in immune cytolysis experiments with dengue-infected cells occurred much later than the peak of infectious virus release. This was in sharp contrast to immune cytolysis with a group A arbovirus, Eastern equine encephalitis, in which the kinetics of release of infectious virus and (51)Cr release were identical. This suggests different mechanisms of insertion of viral plasma membrane antigens in Eastern equine encephalitis and dengue-infected LLC-MK(2) cells.


Detection of nitrogenase components and other nonheme iron proteins in polyacrylamide gels.


Development and application of new equipment for transrectal ultrasonography.


Development of chicken erythrocyte alloantigens in ontogenesis.


Dexamethasone (DXM) effect on the histamine-releasing activity of endotoxin.


Different mode of action of ribonuclease H in purified alpha and alpha beta ribonucleic acid-directed deoxyribonucleic acid polymerase from avian myeloblastosis virus.


Differential extraction of proteins from human placental ribosomes.


Disorders of phagocytic cell function.

Disorders of phagocytic cell function.


Dissociation of slow potentials and phasic multiple unit activity.


Displaced abomasum in dairy cattle: etiological factors.


Dissociation of the inhibitory activities of iodoacetamide (IAc) on specific histamine release and lactate production in human leucocytes.


Distribution of HL-A antigens on blood cells.


Douglas Austen Stanley.

Douglas Austen Stanley.


Distribution of UDPG-glycogen transferase on isolated rat liver glycogen particles.


Drug reactions. 23. Drug induced alopecia.


Dynamic nuclear magnetic resonance spectroscopy.


Drug-induced enteropathy characterized by lipid in macrophages.


Drug-induced foam cell reactions in rats. I. Histopathologic and cytochemical observations after treatment with chlorphentermine, RMI 10.393 and Ro 4-4318.


Dynamics of human sleep sigma spindles.

Dynamics of human sleep sigma spindles.


DNA cytophotometry of chromosomes in a case of chronic myelogenous leukemia.


Early insulin response to glucose injected intravenously in patients with localized granuloma annulare.


Early intervention. Experiences in a Service-Centered Research Program.


Editorial; Hospital medical staffing.

Editorial; Hospital medical staffing.


Ectopic gonadotropin in a case of anaplastic large-cell carcinoma of the lung. A case of ectopic gonadotropin production by a bronchogenic carcinoma is presented. Eleven similar cases have been previously reported. Urine gonadotropin titres appeared related to the size of the tumour mass since they decreased with response to treatment and increased when the tumour started progressing again. The hormone is most probably elaborated and secreted by the tumour cells.


Editorial: A prescription for perspiration.


Editorial: Alimentary endoscopy for all.


Editorial: Antenatal diagnosis of genetic disease.


Editorial: Bongo-drum disease.

Editorial: Bongo-drum disease.


Editorial: Bracken.

Editorial: Bracken.


Editorial: Carcinomatous polymyositis and neuromyopathy.


Editorial: Diagnosis and automation.

Editorial: Diagnosis and automation.


Editorial: Diagnosis of insulinoma.

Editorial: Diagnosis of insulinoma.


Editorial: Encephalopathy and fatty degeneration of viscera.


Editorial: Fire-fighting: an insidious hazard.


Editorial: Functional implications of axoplasmic transport.


Editorial: Growth-hormone release-inhibiting hormone.


Editorial: Haemophilia carriers.

Editorial: Haemophilia carriers.


Editorial: Immune response genes.

Editorial: Immune response genes.


Editorial: Is HL-A matching worth while in kidney transplantation?


Editorial: Leads in oesophageal cancer.

Editorial: Leads in oesophageal cancer.


Editorial: Lung tumours in mice exposed to tobacco smoke.


Editorial: One-parent families.

Editorial: One-parent families.


Editorial: Oral contraceptives and health.


Editorial: Penicillins and nephropathy.

Editorial: Penicillins and nephropathy.


Editorial: Prosopagnosia.

Editorial: Prosopagnosia.


Editorial: Portacaval anastomosis for metabolic disease.


Editorial: Quality of laboratory animals.


Editorial: Science in China.

Editorial: Science in China.


Editorial: Storm in a private bed.

Editorial: Storm in a private bed.


Editorial: Skin infection and the kidney.


Editorial: Subcutaneous heparin.

Editorial: Subcutaneous heparin.


Editorial: Sulphasalazine-induced lung disease.


Editorial: The coeliac philosophy.

Editorial: The coeliac philosophy.


Editorial: The latest of L.A.T.S.

Editorial: The latest of L.A.T.S.


Editorial: Tobacco substitutes and the Hunter committee.


Editorial: Tomorrow's artificial kidney.


Editorial: Transtracheal aspiration.

Editorial: Transtracheal aspiration.


Editorial: Ubiquitous HeLa.

Editorial: Ubiquitous HeLa.


Editorial: Unto everyone that hath.

Editorial: Unto everyone that hath.


Editorial: Use and abuse of the Supraregional Assay Service.


Effect of beta 2 microglobulin antibody on effector function of T-cell mediated cytotoxicity.


Effect of carrier preimmunization on the anti-hapten response in the chicken.


Effect of chronic graded doses of ascorbic acid on thyroid activity, protein bound iodine of blood and deiodinase enzyme of peripheral tissues of guinea pigs.


Effect of early thymectomy on the cellular changes occuring in the spleen of the clawed toad following administration of soluble antigen.


Effect of emetine treatment on kidney aminopeptidase activity.


Effect of estrogen on gene expression in the chick oviduct. 3. Hybridization studies with (3H) messenger RNA and (3H) complementary DNA under conditions of DNA excess.


Effect of exercise on levels of plasma growth hormone, free fatty acids, and glucose in the pigeon.


Effect of sex hormones on feed intake in rats.


Effect of short-term administration of N-nitroso compounds on liver histology and on pentobarbital-induced sleeping time in mice.


Effect of short and long term chlorpropamide treatment of insulin release and blood-glucose.


Effects of bleomycin on 3H-thymidine incorporation in the skin and on the DNA, RNA and ATP syntheses in the primary tumour of patients with vulval carcinoma.


Effects of guanethidine and imidazole on histamine response.


Effects of ketamine on EEG activity in cats and monkeys.


Effects of metabolic inhibitors on vital staining with methylene blue.


Electro-acoustic unit for classroom use.


Effects of post-coital administration of chlormadinone acetate to rats.


Electroencephalographic recordings from deep cerebellar structures in patients with uncontrolled epileptic seizures.


Electron microscope study of mitochondrial 60S and cytoplasmic 80S ribosomes from Locusta migratoria. Purified mitochondrial ribosomes (60S) have been isolated from locust flight muscle. Purification could be achieved after lysis of mitochondria in 0.055 M MgCl(2). Mitochondrial 60S and cytoplasmic 80S ribosomes were investigated by electron microscopy in tissue sections, in sections of pellets of isolated ribosomes, and by negative staining of ribosomal suspensions. In negatively stained preparations, mitochondrial ribosomes show dimensions of approximately 270 x 210 x 215 A; cytoplasmic ribosomes measure approximately 295 x 245 x 255 A. From these values a volume ratio of mitochondrial to cytoplasmic ribosomes of 1: 1.5 was estimated. Despite their different sedimentation constants, mitochondrial ribosomes after negative staining show a morphology similar to that of cytoplasmic ribosomes. Both types of particles show bipartite profiles which are interpreted as "frontal views" and "lateral views." In contrast to measurements on negatively stained particles, the diameter of mitochondrial ribosomes in tissue sections is approximately 130 A, while the diameter of cytoplasmic ribosomes is approximately 180-200 A. These data suggest a volume ratio of mitochondrial to cytoplasmic ribosomes of 1:3. Subunits of mitochondrial ribosomes (40S and 25S) were obtained by incubation under dissociating conditions before fixation in glutaraldehyde. After negative staining, mitochondrial large (40S) subunits show rounded profiles with a shallow groove on a flattened side of the profile. Mitochondrial small subunits (25S) display elongated, triangular profiles.


Effects of cyclophosphamide on B- and T-lymphocytes in rheumatoid arthritis.


Electron microscopic studies of chain initiation complexes and polysomes.


Electrophoretic types of transaldolase, transketolase, and other enzymes in bifidobacteria.


Electron microscopy of enzymes.

Electron microscopy of enzymes.


Electrophysiological studies of hippocampal, septal and midbrain projections to the hypothalamus of the rat.


Electrophysiological investigations of methylmercury intoxication in humans. Evaluation of peripheral nerve by conduction velocity and electromyography.


Elimination of the residual cytoplasmic material by prolonged ribonuclease treatment in gallocyanine-chromalum stained nerve cells fixed in formalin.


Elution of antibody from the skin lesions of patients with pemphigus vulgaris.


Embryonal sarcoma of the lower urinary tract in children: 5-year survival in 2 cases after radical treatment.


Endemic goitre: a public health problem in Maharashtra, India.


Endogenous RNA-directed DNA polymerase activity in virions of RNA tumor viruses and in a fraction from normal chicken cells.


Endometriosis: histological and histochemical findings.


Endoscopy in gastrointestinal bleeding.

Endoscopy in gastrointestinal bleeding.


Enhancement of the immune response of genetically thymus-less mice by different cell populations.


Enzyme-histochemical studies on the cycle in the endocervix and on the isthmus.


Epstein-Barr virus-associated complement-fixing and nuclear antigens in Burkitt lymphoma biopsies.


Epithelial collagens and glycosaminoglycans in the embryonic cornea. Macromolecular order and morphogenesis in the basement membrane. The embryonic corneal epithelium synthesizes both collagen and chondroitin sulfate and excretes them across the basement membrane into the subepithelial space where they assemble into a spiraling orthogonal matrix of fibrils. The assembly of collagen into fibrils is first apparent at the outer face of the basement membrane in a region of ordered chondroitin sulfate molecules. Hyaluronate, another morphogenetically important corneal macromolecule, is produced at these early stages only by the inner endothelium. These correlated biosynthetic and ultrastructural data demonstrate discrete macromolecular products of the two corneal epithelia with differing morphogenetic properties and functions.


Estimation of the activation energy for millisecond delayed fluorescence from uncoupled chloroplasts.


Establishment and characteristics of two unique cell lines from patients with lymphosarcoma.


Ethanol induced alterations of axoplasmic flow in retinal ganglion cells.


Evaluation of the nutritional value of proteins of rape, turnip rape and yellow mustard seed by larvae of the yellow mealworm, Tenebrio molitor L.


Evaluation of the T. pallidum haemagglutination (TPHA) test for syphilis on "problem sera".


Evidence for a physiologic role of erythropoietin in fetal erythropoiesis.


Evidence for a noradrenergic and dopaminergic mechanism in the hyperactivity produced by 4, alpha-dimethyl-m-tyramine (H 77-77) in rats.


Evolutionary relationships between rat and mouse chromosomes.


Evidence for a polysaccharide surface coat in the developmental stages of Leishmania donovani: a fine structure-cytochemical study.


Experimental corneal wound strength.

Experimental corneal wound strength.


Failure of cytosine arabinoside in treating smallpox. A double-blind study.


EEG radio telemetry.

EEG radio telemetry.


Familial neuromuscular disease with "myotubes".


Five years' experience with the Björk-Shiley tilting-disc valve in isolated aortic valvular disease.


Fluorescence labeling of mouse alloantibodies.


Flow microfluorometric analysis of cell killing with cytotoxic drugs.


Five years' experience with iodine-125 therapy of Graves' disease.


Fluorescence spectroscopic and fading behavior of Ehrlich's hyperdiploid mouse ascites tumor cells supravitally stained with acridine orange.


Fluorometric properties of the bibenzimidazole derivative Hoechst 33258, a fluorescent probe specific for AT concentration in chromosomal DNA.


Follow-up study of serum immunoglobulins in thymectomized cases of myasthenia gravis.


Functional and structural proteins of the nervous system. Concluding remarks.


Functional and morphologic characteristics of complement receptor lymphocytes in mice.


Experimental chemotherapy in leprosy, then and now.


Further studies of thyroid function tests in the elderly at home.


Genetic control and immunity.

Genetic control and immunity.


Genitourinary-tract problems of the aged male.


Geoffrey Platt.

Geoffrey Platt.


Germinal centers: a microenvironment for the production of antibody forming cell precursors?


Globin messenger RNA synthesis and processing during haemoglobin induction in Friend cells. I. Evidence for transcriptional control in clone M2.


Glomerular lesions in dysproteinemias.

Glomerular lesions in dysproteinemias.


Glomerulonephritis associated with hepatitis-B surface antigen immune complexes in children.


Genetic alterations in tumor cells resulting in their escape from the immune response.


Glucocorticoid-receptor complexes in rat thymus cells. "Cytoplasmic"-nuclear transformations.


Glycosaminoglycans of epidermis and dermal collagen in dog skin.


Glycosuria and hyperglycaemia after kidney transplantation.


Goldenhar's syndrome, typical and atypical forms. Report of two cases.


Gonococcal disease.

Gonococcal disease.


Haemagglutination and cytotoxic studies of H-2. V. T-e anti-27, 28, 29 family of antibodies.


Hairy hatman to the rescue.

Hairy hatman to the rescue.


Hematologic automation by use of continuous flow systems.


Hemorrhagic shock in the rat: metabolic changes in brain and liver.


Heparin-precipitable fraction (HPF) in an unselected material of dermatological inpatients.


Hepatic morphologic alterations in dogs given 1-t-butylamino-3-(2-chloro-5-methylphenoxy)-2-propanol hydrochloride.


Hepatitis B antigen (HBAg) in the Republic of Ireland: distribution of ad and ay subtypes.


High energy phosphate compounds of gastric tissue in rats.


Hepatitis B antigen: antigenic sites related to human serum proteins revealed by affinity chromatography. Hepatitis B antigen-associated particles, isolated from sera of antigen carriers, were submitted to affinity chromatography on columns of insolubilized antibodies to normal human plasma. The particles adsorbed to the immunosorbent at pH 7.2 and were subsequently eluted at pH 2.2. Exposure of the particles to 8 M urea, 5 M KI, pH 2.2, detergents, organic solvents, or proteolytic enzymes failed to prevent their subsequent adsorption to the immunosorbent. This suggests that antigenic determinants related to human plasma proteins are constituent components of hepatitis B antigen-associated particles. These determinants are distinct from the group-specific (a) and subtype-specific (d or y) sites of the hepatitis B antigen and appear to be related to antigenic specificities on prealbumin, albumin, apolipoproteins C and D, and the gamma-chain of immunoglobulin G.


High frequency of antibiotic-resistant enterobacteria in the River Stour, Kent.


High resolution shading correction.

High resolution shading correction.


High titre antiserum specific to aldosterone.


High-resolution analysis of the modified quarter-stagger model of the collagen fibril.


Histamine release from mast cells by highly purified phospholipase C (alpha-toxin) and theta-toxin from Clostridium perfringens.


Histamine release in endotoxin shock: effect of dexamethasone administration.


Histochemical evidence for the existence of adreno-melanogenic tissue in the teleost fish Nandus.


Histochemical investigations on the epidermis of the electric fish Malopterurus electricus Lacép. (Teleostei: Malopteruridae).


Histochemical studies of the monoamine oxidase during the development of the chick.


Histochemical and radioautographic studies of normal human fetal colon.


Histochemistry of acid glycosaminoglycans (mucopolysaccharides) in the branchial epithelium of Selachians.


Histochemistry and ultrastructure of the cell surfaces of the guinea pig kidney with quantitative data on carbohydrate components of glycosaminoglycans of kidney.


Histochemistry of provisional calcification of cartilage in heterotopic implants of bone matrix.


Histological evidence supporting the inferior olive as the major source of cerebellar climbing fibers in the rat.


Home treatment for patients with haemophilia.


Homing of B-lymphocytes to follicles: specific retention of immunologically committed cells.


Homozygous hypercholesteraemia and the portacaval shunt. The need for a concerted attack by surgeons and clinical researchers.


Hyaline ("colloid") cytoplasmic inclusions in motoneurones in association with familial micrencephaly, retardation and seizures.


Hyperthyroidism and pregnancy.

Hyperthyroidism and pregnancy.


Hybridization characteristics of enzymatically synthesised DNA complementary to mouse immunoglobulin messenger RNA.


Hypothalamo-hypophysial neurosecretory and portal system of the Indian wall lizard, Hemidactylus flaviviridis.


HL-A antigens in leprosy.

HL-A antigens in leprosy.


HL-As and the immune response to gluten.


Identification of cell surface immunoglobulin markers by protein A-containing fluorescent staphylococci.


Identification of chromosome anomalies in the blastic phase of chronic myelocytic leukemia (CML) by Giemsa- and quinacrine-banding techniques.


Identification of viral reverse-transcriptase.


IgG complexes in serum of rheumatoid arthritis patients.


Immune activation of B cells: evidence for "one non-specific triggering signal" not delivered by the Ig receptors.


Immunochemical studies on human fibrinogen and its fragments. Cross-reactivity of NH2-terminal "Disulfide Knot" and related structures as determined by radioimmunoassay.


Immunodeficiency diseases: functional classification.


Immunofluorescent localization of alpha-fetoprotein synthesis in endodermal sinus tumor (yolk sac tumor).


Immunoglobulin surface determinants on chicken lymphoid cells.


Immunological responses of guinea pigs to a synthetic autoantigen of brain.


Immunoreactive polypeptide hormones in the pancreas and gut of the lamprey.


Immunosuppression of the thymectomized fetal lamb and its neonatal reconstitution.


Importance of coagulase-negative staphylococci as pathogens in the urinary tract.


Importance of feed as an unavoidable source of pesticide contamination in poultry meat and eggs. 1. residues in feedstuff.


Importance of feed as an unavoidable source of pesticide contamination in poultry meat and eggs. 2. Residues in eggs and tissues.


In vitro antibody response to a distinct antigenic determinant of Escherichia coli beta-D-galactosidase. Effect of antigen dosage and co-cultivation of lymph node fragments on peak titres and duration of antibody synthesis.


In vitro organ culture of adult human and mouse skin.


In vitro studies of testosterone and 5alpha-dihydrotestosterone binding in benign prostatic hypertrophy.


Incorporation of L-dopa, L-alpha-methyldopa and DL-isoproterenol into guinea pig hair.


Increased serum immunoglobulin levels following portacaval shunt in the normal rat. Normal rats subjected to end-to-side portacaval shunt showed decreased survival and weight gain, a progressive fall in serum albumin and reciprocal rise in serum gamma globulin when compared with sham-operated controls for 12 weeks. Antibacterial lipopolysaccharide antibody was detected in significant titre at the sixth and twelfth weeks. It is suggested that the elevated levels of gamma globulin and reversal of albumin/globulin ratios noted in these animals may represent an immune response to bacterial lipopolysaccharides released into the systemic circulation as a result of the portacaval shunt. The hyperglobulinaemia of cirrhosis in human subjects may have a similar aetiology.


Indications for early haemodialysis in multiple trauma.


Increased DNA synthesis in vitro in guinea-pigs unresponsive to DNP--skin protein conjugate.


Indirect fluorescent antibody techniques for demonstration of trout viruses and corresponding antibody.


Induction and suppression of experimental allergic encephalomyelitis in the non-human primate.


Induction of anti-alloantibodies by alloantibody fragments.


Induction of anti-hapten antibody responses against haptens conjugated to autologous and heterologous proteins.


Induction of host nuclear DNA synthesis in coccidia-infected chicken intestinal cells.


Influence of fasting and refeeding on the elongation process in rat liver.


Influence of hypoxia on the occurrence of the lactate dehydrogenase release from isolated perfused rat heart.


Influence of light, riboflavin, and carotene on the response of rats to the acute toxicity of aflatoxin and monocrotaline.


Influence of muscular exercise on plasma level of growth hormone in diabetics with and without retinopathy.


Influence of possible HL-A haploidentity on renal-graft survival in Eurotransplant.


Inhibition of guinea-pig complement by derivatives of benzamidine. I. Effect of p-nitrophenylureido derivative of m-(m-phenoxypropoxy)benzamidine on guinea-pig complement component haemolytic activity.


Inhibition of RNA directed DNA polymerase of murine leukemia virus by 2'-O-alkylated polyadenylic acids.


Innervation of human atrioventricular valves.


Interaction aspects of antimycobacterial drugs in the chemotherapy of tuberculosis. I. Role of individual antituberculous drugs in drug regimens used in the chemotherapy of human tuberculosis.


Interaction between erythrocyte membrane proteins and complement components. I. The role os -S-S linkages as revealed by two-dimensional sodium dodecylsulfate-polyacrylamide gel electrophoresis.


Interaction of bishydroxycoumarin with chloral hydrate and trichloroethyl phosphate.


Interaction of human anaphylatoxin C3a with rat mast cells demonstrated by immunofluorescence.


Interactions of fluorescent mercurial compounds and acidic fluorochromes with isolated living cells and nuclei.


Interneuronal epileptic discharges related to spike-and-wave cortical seizures in behaving monkeys.


Intracellular aluminum binding; a histochemical study.


Iodine contamination of the serum protein-bound iodine: incidence and clinical significance. Iodine contamination as defined by the combination of a raised (PBI-T(4)I) difference and low (131)I neck uptake was found in 38 (17.5%) of 217 euthyroid patients. Of these, 17 had PBI levels of greater than 20 mug/dl but in the remainder levels were clinically feasible. In only 21 was there a history of exposure to iodine. Two of 12 hypothyroid patients had PBI levels well within normal limits. False elevation of the PBI is thus shown to be common. It is neither always obvious nor can it be easily avoided. The PBI is not an acceptable alternative to T(4) estimation by other methods.


Intrinsic mutagenesis, an interpretation of the pathogenesis of xeroderma pigmentosum.


Irradiated cerebellar medulloblastoma in a monozygotic twin. Growth, neurology and chromosomes 13 years after treatment.


Isoelectric focusing of proteins exposed to sodium dodecyl sulfate.


Isolation and characterization of a 5S RNA-protein complex from human placental ribosomes.


Isolation of a new urine metabolite excreted in generalized congenital analgesia.


Interference with formation and expression of RNA tumor virus information: rationale and experimental results.


Isolation and partial characterization of macromolecular urinary aggregates containing carcinoembryonic antigen-like activity. Carcinoembryonic antigen-like substances in the urine of patients with bladder carcinoma and of healthy male subjects occur in a wide range of average molecular sizes. Some of these substances are glycoproteins giving reactions of antigenic identity with carcinoembryonic antigen (CEA) derived from colorectal carcinoma and occur in aggregation with proteins showing antigen specificities of albumin, haptoglobin and the heavy chains of immunoglobulins G, A and M. Recoveries of CEA-like activities, following Sepharose 4B chromatography of urinary materials of molecular size > 3 × 10(4), varied from 40 to 1530%. Treatment with 1 mol/1 HClO(4) caused an apparent solubilization of 85% of the CEA-like activity of such materials from the urine of a patient with bladder carcinoma and raised the specific CEA-like activity of the solubilized product to 379% of that of the untreated materials.


Isolation of a surface glycoprotein of human platelets.


Isolation, structure and synthesis of a new heterocyclic glucoside from Lathyrus odoratus: 2-(beta, D-glucopyranosyl)-3-isoxazolin-5-one.


Janet Simpson Ferguson Niven.

Janet Simpson Ferguson Niven.


Labeled staphylococcal protein A as an immunological probe in the analysis of cell surface markers.


Laboratory examination of the thyroid. I. In vitro tests. Last of a series.


Laboratory examination of the thyroid. 1. In vitro tests.


Lack of incorporation of 1:N6-ethenoadenosine triphosphate into yeast tRNAPhe and tRNASer under standard conditions.


Laryngeal lesions in Urbach-Wiethe disease (lipoglycoproteinosis; lipoid proteinosis; hyalinosis cutis et mucosae). A histopathological and clinical study, including direct laryngoscopical examinations.


Late effects of spinal cord irradiation with 300 kV X rays and 15 MeV neutrons.


Letter: "Menstrual toxin" and human fertility.


Letter: A cold autoagglutinin in the newborn.


Letter: A metabolite of bleomycin A5 in rabbit urine.


Letter: Acrodermatitis enteropathica: a lethal inherited human zinc-deficiency disorder.


Letter: Adrenal unresponsiveness associated with clobetasol propionate.


Letter: Afferent blockage, oestrogenic therapy, and malignancy.


Letter: Alpha 1-antitrypsin null gene (pi-).


Letter: Allopurinol and bone-marrow depression.


Letter: Alpha-fetoprotein radioimmunoassay in blood diseases.


Letter: Ampicillin-resistant Haemophilus influenzae meningitis.


Letter: Ampicillin-resistant Haemophilus influenzae.


Letter: An adverse reaction to althesin.


Letter: Another case of Whipple's disease?


Letter: Angio-immunoblastic lymphadenopathy with dysproteinaemia.


Letter: Apparent emergence of gentamicin-resistant Providencia stuartii during therapy with gentamicin.


Letter: Assessment of response to treatment in advanced breast cancer.


Letter: Autologous transfusion.

Letter: Autologous transfusion.


Letter: Awareness during anaesthesia.

Letter: Awareness during anaesthesia.


Letter: Bacteriuria in preschool children.


Letter: Beta-blocking agents in the treatment of catecholamine-induced symptoms in musicians.


Letter: Bilharzial urethral discharge.

Letter: Bilharzial urethral discharge.


Letter: Blood-lead levels, behavior, and intelligence.


Letter: Bone necrosis in tunnel workers.


Letter: Cancer of the cervix: a sexually transmitted infection?


Letter: Cerebral intravascular coagulation in diabetic ketoacidosis.


Letter: Chemistry of bleomycin. XIV. Biogenetic-like synthesis of (2S, 3S, 4R)-4-amino-3-hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin.


Letter: Chemistry of bleomycin. 8. The x-ray structure determination of 4-amino-3-hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin.


Letter: Chloromycetin: medical imperialism.


Letter: Cholera.

Letter: Cholera.


Letter: Chondroitinsulphaturia with alpha-L-iduronidase deficiency.


Letter: Church, state, and people.

Letter: Church, state, and people.


Letter: Classification of non-Hodgkin's lymphomas.


Letter: Clotting factors in von Willebrand's disease.


Letter: Colonoscopic polypectomy.

Letter: Colonoscopic polypectomy.


Letter: Comparison of the effects of early and late fixation on Alcian Blue staining in dog skin using two different fixatives.


Letter: Complement components in cystic fibrosis.


Letter: Cryptorchidism.

Letter: Cryptorchidism.


Letter: Congenital heart defects and prenatal sex hormones.


Letter: D.N.C.B. skin test in hepatitis.


Letter: Decrease of T lymphocytes during ageing.


Letter: Detection of microbial antigens.


Letter: Diet and coronary heart-disease.


Letter: District community physicians.

Letter: District community physicians.


Letter: Domiciliary physiotherapy.

Letter: Domiciliary physiotherapy.


Letter: Emigration and mental subnormality in Northern Ireland.


Letter: Endotoxin and stress.

Letter: Endotoxin and stress.


Letter: Evaluation of kwashiorkor and marasmus.


Letter: Evolution of kwashiorkor and marasmus.


Letter: Follow-up of urinary-tract infection in children.


Letter: Food antibodies and myocardial infarction.


Letter: Future of the N.H.S.

Letter: Future of the N.H.S.


Letter: Gamma-globulin and congenital rubella.


Letter: General practitioners' opinions of a new hospital-discharge letter.


Letter: Genetic diagram of the human family.


Letter: Geriatrics is medicine.

Letter: Geriatrics is medicine.


Letter: Geriatrics.

Letter: Geriatrics.


Letter: Glucagon antibodies in diabetic patients.


Letter: Group-Z meningococci.

Letter: Group-Z meningococci.


Letter: Growth of respiratory syncytial virus in RK13 cells.


Letter: Haemagglutination-inhibition slide test for hepatitis-B antigen.


Letter: Haemophilia carriers.

Letter: Haemophilia carriers.


Letter: Haemorrhagic thyroid cysts in nodular goitre.


Letter: Histocompatibility testing in doubtful cases of ankylosing spondylitis.


Letter: Hodgkin's disease mortality among physicians.


Letter: Hyperosmolar coma in Cushing's disease.


Letter: Hypertension: a direction for research.


Letter: Hypotension after percutaneous liver biopsy.


Letter: Hypotension during administration of angiotensin converting enzyme inhibitor SQ 20,881.


Letter: HL-A antigens and coeliac disease.


Letter: Immunoelectron microscopy and histochemistry of HB Ag.


Letter: Imported infections.

Letter: Imported infections.


Letter: Indomethacin and bone pain.

Letter: Indomethacin and bone pain.


Letter: Industrial action in the N.H.S.

Letter: Industrial action in the N.H.S.


Letter: Inhibition of lymphocyte response to stimulants induced by unsaturated fatty acids and prostaglandins.


Letter: Iron and resistance to infection.


Letter: Ionic shuttles in shock.

Letter: Ionic shuttles in shock.


Letter: Kveim reagent.

Letter: Kveim reagent.


Letter: Ischaemia times in renal transplants.


Letter: Kwashiorkor and tuberculosis.

Letter: Kwashiorkor and tuberculosis.


Letter: Lactic acidosis and hyperlactataemia.


Letter: Larger doses of immunosuppressive drugs.


Letter: Levodopa in treatment of myoclonus.


Letter: Leukaemia and lower-motor-neuron disease.


Letter: Local chemotherapy for pseudomonas lung abscess.


Letter: Local immunity and ulcerative colitis.


Letter: Magnesium deficiency and hypocalcaemia.


Letter: Management of acute myocardial infarction.


Letter: Manual cardiotocography in labour.


Letter: Medical nemesis.

Letter: Medical nemesis.


Letter: Metabolic and hormonal response to acute myocardial infarction.


Letter: Mobile coronary care.

Letter: Mobile coronary care.


Letter: Mortality and anaemia.

Letter: Mortality and anaemia.


Letter: Mycoplasma and fertility.

Letter: Mycoplasma and fertility.


Letter: N.B.T. test in overwhelming bacterial infection.


Letter: Nature of crystalline chenodeoxycholic acid.


Letter: Nature of nuclear projections in an adenocarcinoma of the breast.


Letter: Neonatal cold injury and maternal reserpine administration.


Letter: Neural-tube defects and twinning.


Letter: New concepts in medical education.


Letter: New enterovirus type associated with epidemic of aseptic meningitis and-or hand, foot, and mouth disease.


Letter: Nitrous-oxide asphyxia.

Letter: Nitrous-oxide asphyxia.


Letter: Nomenclature and abbreviations for vitamin D metabolites.


Letter: Non-congenital rubella encephalitis.


Letter: Occupational hazard of halothane.


Letter: On medical imperialism.

Letter: On medical imperialism.


Letter: Oral contraception: potential hazards of hormone therapy during pregnancy.


Letter: Oral contraceptives and allergy.


Letter: Oral contraceptives and health.

Letter: Oral contraceptives and health.


Letter: Pathologists at the crystal ball.


Letter: Pathogens in the urinary tract.

Letter: Pathogens in the urinary tract.


Letter: Peak-flow meter v. peak-flow gauge.


Letter: Penicillinase production by Haemophilus influenzae.


Letter: Pentazocine, mefenamic acid and hypertonic-saline abortion.


Letter: Peripheral lymphocyte counts in colonic disease.


Letter: Phenelzine and acetylator status.


Letter: Plasma viscosity and pre-eclampsia.


Letter: Polyploidal giant cells in a laryngeal biopsy.


Letter: Pneumococcus with increased resistance to penicillin.


Letter: Preparing multiple doses of bleomycin sulfate.


Letter: Prevention of deep-vein thrombosis.


Letter: Prolactin and migraine.

Letter: Prolactin and migraine.


Letter: Prolactin and the immune response.


Letter: Propranolol in Parkinson's disease.


Letter: Prostaglandins and pre-eclampsia.


Letter: Protein requirements.

Letter: Protein requirements.


Letter: Pseudomembranous colitis associated with clindamycin.


Letter: Pulsus paradoxus in asthma.

Letter: Pulsus paradoxus in asthma.


Letter: Radioimmunoassay of alpha-fetoprotein in gastrointestinal diseases.


Letter: Recovery from hemianopia in man: evidence for collicular vision?


Letter: Rapid assay of gentamicin.

Letter: Rapid assay of gentamicin.


Letter: Relief of action myoclonus by 5-hydroxytryptophan.


Letter: Retrolental fibroplasia.

Letter: Retrolental fibroplasia.


Letter: Rifampicin in co-oncogenic experiments.


Letter: Rosetting cells in autoimmune haemolytic anaemia.


Letter: Rubella antibody titres in rheumatoid arthritis.


Letter: S.I. units.

Letter: S.I. units.


Letter: Schistosomes in Vietnam.

Letter: Schistosomes in Vietnam.


Letter: Seasonal variation of histological osteomalacia in femoral-neck fractures.


Letter: Serum-cholesterol after renal transplantation.


Letter: Serum-ferritin.

Letter: Serum-ferritin.


Letter: Serum-gentamicin levels after intravenous bolus injection.


Letter: Small doses of insulin in the treatment of diabetic "coma".


Letter: Somatic-cell mutation and cancer.


Letter: Staining techniques.

Letter: Staining techniques.


Letter: Splenic lymphocytes in chronic myeloid leukaemia.


Letter: Stereotaxy for obesity.

Letter: Stereotaxy for obesity.


Letter: Subcutaneous heparin and postoperative thromboembolism.


Letter: Subnormality and psychiatry.

Letter: Subnormality and psychiatry.


Letter: Synthesis of high-molecular-weight antihaemophilic factor in von Willebrand's disease.


Letter: T and B cells in human spleen.

Letter: T and B cells in human spleen.


Letter: T lymphocytes in infectious mononucleosis.


Letter: Telling the parents.

Letter: Telling the parents.


Letter: Terminology in biliary radiology.


Letter: Thanatophoric dwarfism in triplets.


Letter: The bran hypothesis.

Letter: The bran hypothesis.


Letter: The bran-hypothesis.

Letter: The bran-hypothesis.


Letter: The cons of group psychotherapy.


Letter: The empty sella.

Letter: The empty sella.


Letter: The megavitamin scene.

Letter: The megavitamin scene.


Letter: The Feulgen reaction in polyvinyl alcohol or polyethylene glycol solution. "Fixation" by excluded volume.


Letter: Thyrotrophin-releasing hormone in depression.


Letter: Transfusion of fresh blood in the newborn period.


Letter: Transfusion of fresh blood in the newborn.


Letter: Translocation of intrauterine contraceptive devices.


Letter: Treatment of cystic fibrosis.

Letter: Treatment of cystic fibrosis.


Letter: Treatment of haemophilia.

Letter: Treatment of haemophilia.


Letter: Treatment of paracetamol overdosage.


Letter: Undergraduate training in occupational medicine.


Letter: Unsaturated fatty acids and renal transplantation.


Letter: Urea treatment of skin malignancies.


Letter: Varicose veins in tropical Africa.


Letter: Vibrio parahaemolyticus.

Letter: Vibrio parahaemolyticus.


Letter: Virus particles in acute gastroenteritis.


Letter: Visceral malignancy and non-grey hair.


Letter: Vitamin B 6, depression, and oral contraception.


Letter: Weather and myasthenic fatigue.

Letter: Weather and myasthenic fatigue.


Letter: Wrinkling of skin in cystic fibrosis.


Letter: X long-arm deletion with features of Turner's syndrome.


Letters: Comment on Solcia and Buffa's "Azo coupling of indole-reactive enterochromaffin cells".


Liberation of vasoactive materials from mast cells in anaphylactic shock.


Light and electron microscopy of the islets of langerhans of the ground squirrel (Citellus citellus).


Liver-cell adenomas and peliosis hepatis in mice associated with oxazepam.


Liquid scintillation radioassay in disposable microcentrifuge tubes: radioimmune precipitates and other applications. A simple, economical radioassay system employing disposable polypropylene microcentrifuge tubes was developed. Plastic adapters permitted automatic operation in liquid scintillation spectrometers. Counting efficiencies of (3)H, (14)C, (32)P, and (125)I in liquid scintillation cocktails and of (32)P by Cerenkov radiation (at lower efficiency in absence of added scintillator) were comparable to those in standard vials. Multipurpose use of the microtubes made the system versatile and expedient, e.g., collection of precipitates and radioassay in the same container. Collection of radioimmune precipitates was aided by a carrier inorganic precipitate, Mg(2)P(2)O(7).


Loss of epithelial blood group antigen-A during wound healing in oral mucous membrane.


Lymph node function and lymphocyte circulation in the pig.


Lymphocyte differentiation in the chicken embryo--relationship to the microenvironment.


Lymphadenopathy simulating the malignant lymphomas.


Lymphocytes sensitised to basic encephalitogen in patients with multiple sclerosis unresponsive to steroid therapy.


Lysogeny and lysosensitivity in Shigella dysenteriae group of bacteria. 3. Serological specificity of receptors of T2 and T4 phages in Shigella dysenteriae 7, strain D7.


Macrophages bearing hapten-carrier molecules as foci inducers for T and B lymphocyte interaction.


Maintenance of synaptic membranes by the fast axonal flow.


Malignant disease of the lymphoid system in immunological perspective.


Management of childhood leukemia.

Management of childhood leukemia.


Management of terminal illness.

Management of terminal illness.


Managing carcinoma of the bladder.

Managing carcinoma of the bladder.


Marrow adipose cells. Ultrastructural and histochemical characterization.


Maintenance of adult rhesus monkey motor neurons in tissue culture.


Measurement of circulating desialylated glycoproteins and correlation with hepatocellular damage. Addition of increasing amounts of (125)I-labeled desialylated thyroxine-binding globulin (DTBG) to hepatic cell membranes resulted in a progressive increase in binding. Saturability of membrane sites was indicated by a concentration beyond which further increases in [(125)I]DTBG resulted in no further binding. The binding curve for [(125)I]DTBG was similar to binding curves of desialylated orosomucoid, fetuin, and ceruloplasmin. An inhibition assay system using hepatic cell membranes showed that desialylated orosomucoid had a greater affinity for membrane binding sites than did DTBG but desialylated fetuin and ceruloplasmin bound less avidly than DTBG. Serum from normal persons and patients with a variety of illnesses was tested for its ability to inhibit [(125)I]DTBG binding. The inhibitory activity of 1 ml of normal serum was equivalent to that of 0.2-2 mug DTBG. Patients with Laënnec's cirrhosis, biliary cirrhosis, and hepatic metastases had greatly increased inhibitory activity in their serum. Patients with jaundice due to extrahepatic obstruction had inhibitory activity not significantly different from that found in normal serum. Column chromatography of normal serum on Sephadex G-200 resulted in inhibitory activity throughout the range of protein molecular weight. Desialylation of normal serum with neuraminidase enhanced the inhibitory activity but did not change the distribution of the activity. Gel chromatography of cirrhotic serum showed markedly increased inhibitory activity associated with the macroglobulins and the 4.5S peak and a new peak of inhibitory activity in the low molecular weight area was also seen. Inhibition of desialylated glycoprotein binding to liver cell membranes by serum from patients with hepatocellular disease raises the possibility that desialylated serum glycoproteins accumulate in the circulation and that patients with compromised hepatocellular function may no longer be able to clear them from the circulation. Alternatively, accumulation of desialylated glycoproteins in the circulation could result from defective protein synthesis by the diseased liver.


Mechanism of antigen binding to receptor antibody in B cell immunity and tolerance in vitro.


Mediators of cellular hypersensitivity and immunity including immunologically specific factors.


Membrane antigens characteristic of human lymphoid cells in established cultures.


Microfluorometric analysis of deoxyribonucleic acid replication kinetics and sister chromatid exchanges in human chromosomes.


Micropolygyria: a histopathological and biochemical study.


Modulation of the immunological release of the eosinophil chemotactic factor of anaphylaxis from human lung.


Molecular organization in bacterial cell membranes. 3. Components of a "soluble" fraction obtained by n-butanol extraction of Streptomyces albus membranes.


Molecular-weight estimates of milk-fat-globule-membrane protein-sodium dodecyl sulphate complexes by electrophoresis in gradient acrylamide gels. The molecular weights of milk-fat-globule-membrane proteins solubilized in sodium dodecyl sulphate were estimated by gradient gel electrophoresis. Standard curves were calibrated from both protein and glycoprotein markers of known molecular weight. Six major proteins were observed with Coomassie Blue staining and six with periodic acid-Schiff staining. The behaviour of the membrane proteins and the marker proteins was compared on several different single strength sodium dodecyl sulphate-polyacrylamide gels between 3 and 12% (w/v). The results were used to calculate the free electrophoretic mobility and retardation coefficient of each protein. Glycoprotein markers had a significantly lower mean free electrophoretic-mobility value than the protein markers. Three of the milk-fat-globule-membrane glycoproteins were shown to be independent of any of the Coomassie Blue-stained bands. On the basis of a comparison of the free electrophoretic-mobility and retardation- coefficient values of markers and unknown proteins the most appropriate standard curve for molecular-weight estimation was chosen.


Morphologic identification of microperfused-fixed single nephrons during renal micropuncture.


Mucin histochemistry of mucous carcinomas of breast and colon and non-neoplastic breast epithelium. Although epithelial mucin has been demonstrated in ordinary mammary duct carcinomas, it is formed profusely in the uncommon mucous carcinomas. A histochemical study of mucous carcinomas of the breast and colon showed that both types produce similar mucins, viz, acid and neutral, although the mammary carcinomas produce more neutral mucin and small amounts of sulphated mucins are produced by colonic tumours. Similar studies on sections of normal breast and cystic mammary dysplasia have shown that intracellular neutral mucin was present in the ducts and lobules, and that intracellular acid mucin was present within cells of the terminal ducts and lobules. It was demonstrated enzymatically that the acid mucins produced by the normal and neoplastic tissues is sialic acid. Hence it can be shown that the mucin produced by mucous carcinomas is of epithelial rather than connective tissue type. It is contended that mucous carcinoma of breast arises by metaplasia of duct cells that have already undergone malignant change and not from the lobules of the breast.


Monoamine oxidase and cerebral uptake of dopaminergic drugs. The brain uptake of amines that do not enter the brain or enter it poorly was promoted by noncompetitive inhibitors of monoamine oxidase, as shown by behavioral and chemical criteria. Mice pretreated with water or enzyme inhibitors other than those mentioned were placid after receiving dopamine (3,4-dihydroxyphenethylamine). Mice pretreated with monoamine oxidase inhibitors (nialamide or iproniazid) showed upon treatment with dopamine the brisk motor responses characteristic of treatment with its precursor, L-dopa (3,4-dihydroxyphenylalanine). After receiving dopamine, intact nialamide-pretreated mice showed marked increases of brain dopamine, in contrast to water-pretreated test mice or water-treated controls. In unilaterally caudectomized, nialamide-pretreated mice, dopamine induced marked lateral curving of the body toward the lesion followed by running in that direction. Noradrenaline or adrenaline induced curving in caudectomized mice, whereas intact ones remained placid.These catecholamines are bound and inactivated by monoamine oxidase. The cerebral uptakes of chemicals that are bound but not inactivated by monoamine oxidase were thereafter tested. Nialamide induced increased behavioral responses to apomorphine and to N-propyl noraporphine, increased cerebral concentrations of both, and a deep coloration of the brain from methylene blue (bound by monoamine oxidase) but not Evans blue (bound by albumin). Even large doses of nialamide, however, failed to affect the behavioral responses to oxotremorine, which has cholinergic rather than adrenergic or dopaminergic properties. Mitochondrial monoamine oxidase seems therefore to play a specific regulatory role in the transport of substances that it binds, either to inactivate or to release them.


Morphological study of the human ovary and mammary gland under the long-term effect of progestational agents. A morphological study of the effects of injectable medroxyprogesterone acetate, chlormadinone acetate, norethisterone enanthate, or deladroxate on the ovaries and mammary glands of 52 women is presented.  The lack of evidence of ovulation and corpora lutea formation was confirmed by low urinary pregnanediol excretion levels.  The luteinized follicles showed no evidence of 3beta-hydroxysteroid or 20alph-hydroxysteroid activity of enzymatic dehydrogenases.  There were no marked histological changes observed in the follicles, cortex, stroma, and corpora albicantia.  No significant evidence of fibrosis was found, though there were various degrees of concentration of connective tissue.  80 of 105 patients for whom data were available became pregnant after discontinuing treatment.  No mammary pathology or tumors were detected in 600 patients treated with either medroxyprogesterone acetate or chlormadinone acetate.


Myelin basic proteins.

Myelin basic proteins.


Myopathy associated with pigmentary degeneration of the retina and high protein content of cerebrospinal fluid.


Nail growth: 30 years of observation.

Nail growth: 30 years of observation.


Naphthyl phosphates as substrates for fructose 1,6-diphosphatase.


Native and artificial energy conserving sites operating in coupled electron donor systems for photosystem II.


Natural history of autoimmune achlorhydric atrophic gastritis. A 1-15-year follow-up study.


Naturally occurring arterial lesions in New World primates.


Natural history of hypertension. A case for selective non-treatment.


Neurotoxicological effect of small quantities of lindane. Animal studies.


New assessment centre for children.

New assessment centre for children.


Molecular evidence for viral agents in human cancer and its chemotherapeutic consequences.


New aspects of histaminopexy.

New aspects of histaminopexy.


Nile blue staining of cells in amniotic fluid for fetal maturity. I. A reappraisal.


Nile blue staining of cells in amniotic fluid for fetal maturity. II. In complicated obstetric cases.


No evidence for an immunological cross-reaction between encephalitogenic myelin basic protein and histones.


No-effect levels of organochlorine pesticides based on induction of microsomal liver enzymes in short-term toxicity experiments.


Nuclear images of cells in different functional states.


Nutrition and immunological responsiveness. T-cell function in the offspring of lipotrope and protein-deficient rats.


On the diagnosis of rare paraproteins.

On the diagnosis of rare paraproteins.


On the immunological properties of preserved tissues.


Obituary. Rupert Samuel Bruce Pearson.

Obituary. Rupert Samuel Bruce Pearson.


On the regeneration and repair of superficial wounds in the skin of Rita rita (Ham.) (Bagridae, Pisces).


On the mechanism of interferon induction by polynucleotides. Suppressive effect of poly(rI)--poly(rC) on the liberation of histamine by polycations.


On the 3 alpha-hydroxysteroid dehydrogenase from Pseudomonas testosteroni. Purification and properties.


Organization of the invading lymphoid tissue in human lymphoid thyroiditis.


Pacemaker treatment. I. Indications for cardiac pacing and patient survival.


Partial trisomy 8: further observation of a familial C-G translocation chromosome identified by the Q-staining methods.


Participation of endogenous vasoactive agents in the pathogenesis of endotoxin shock.


Participation of lipopolysaccharide genes in the determination of the enterobacterial common antigen: analysis of R mutants of Salmonella minnesota. A series of R (rough) Salmonella minnesota mutants with rfb, rfe, and rfa mutations leading to various defects in the biosynthesis of cell wall lipopolysaccharide was analyzed as to their enterobacterial common antigen (CA) content. All mutants that had functional rfe genes were CA(+) as is the wild-type parent. This includes mutants with the most defective lipopolysaccharide core types, demonstrating that core structures are not a necessary part of CA. All rfe(-) mutants (complete lipopolysaccharide core, defective synthesis of O side chains) were defective in the synthesis of CA. A smooth strain was accidentally found to be CA(-); the mutation responsible for this defect was also located, like rfe, very close to ilv.


Pathogenesis of membranous glomerulonephritis.


Periodic acid-Schiff reaction, a useful index of duration of complete remission in acute childhood lymphocytic leukemia.


Pesticide stability in cold-stored plant parts, soils, and dairy products, and in cold-stored extractives solutions.


Phosphorylation of rat liver nuclear acidic phosphoproteins after administration of alpha-1,2,3,4,5,6-hexachlorocyclohexane in vivo.


Phototransduction mutants of Drosophila melanogaster.


On the triggering mechanism of anaphylactic reactions in rat mast cells.


Pick's disease. Histological and clinical correlations.


Oncocognitive autoimmunity.

Oncocognitive autoimmunity.


Physiological and morphological identification of hypothalamic magnocellular neuroendocrine cells in goldfish preoptic nucleus. 1. Intracellular recordings were made from antidromically identified neurones in the goldfish preoptic nucleus and Procion Yellow was ejected from the recording pipette, marking these magnocellular neuroendocrine cells diffusely, for histological identification.2. In confirmation of earlier studies these preoptic neuroendocrine cells showed resting membrane potentials of 47 mV, action potentials up to 85 mV, action potentials of long duration (3.9 msec) occurring in two steps, long-lasting hyperpolarizing after-potentials and orthodromic driving from olfactory input.3. Magnocellular neuroendocrine cells exhibited all-or-none jumps to shorter antidromic latencies as pituitary stimulus strength increased, suggesting multiple branching of the ;axones' either near the preoptic nucleus or within the neural lobe.4. I find three morphological types of neuroendocrine cells throughout the magnocellular part of the preoptic nucleus. Cell Type I is a large (37 mum), multipolar neurone, 48 mum from the ependyma, with fine ;dendrites' projecting into the lateral hypothalamus and within the preoptic nucleus, with multiple branched ;axones'. Cell Type II is a large (31 mum), multipolar neurone, 24 mum from the ependyma, with a coarse ;dendrite' to the ependyma and fine ;dendrites' within the preoptic nucleus, with limited ;axonal' branching. Cell Type III is a small (18 mum), multipolar neurone, 46 mum from the ependyma, with fine ;dendritic' processes distributed within the preoptic nucleus, with limited ;axonal' branching.5. I conclude that magnocellular neuroendocrine cells show electrical membrane properties of other central neurones with both physiological and morphological evidence for multiple ;axonal' branching. The three identifiable neuroendocrine cell types (I, II, III) are distributed widely within the anatomical limits of the preoptic nucleus, pars magnocellularis, with each type receiving ;specific' input connexions and with unique output pathways. I suggest that these three types of neuroendocrine cells may be related to the ;cellular' secretion of ;specific' neurohypophysial hormones and neurophysins.


Placental free-fatty-acid transfer and fetal adipose-tissue development: an explantation of fetal adiposity in infants of diabetic mothers.


Polychlorinated biphenyl-induced alteration of biologic parameters in the rat.


Possibilities now available in the study of the Y chromosome in human cells.


Positive occipital sharp transients of sleep: relationships to nocturnal sleep cycle in man.


Possible role of lymphokines in the development of ectopic lymphoid foci in the chicken.


Postoperative course of vesicoureteral reflux associated with benign obstructive prostatic disease.


Pour-on insecticides for the control of cattle lice (Linognathus vituli and Damalinia bovis).


Preferential location of chlorambucil-induced breakage in the chromosomes of normal human lymphocytes.


Predictive value of ST-segment displacement and other indices after myocardial infarction.


Preparation of clinical gynecologic specimens for automated analysis. An overview.


Pregnancy following autograft transplantation of Fallopian tube and ovary in the rabbit. A microsurgical technique for autograft transplantation of the rabbit oviduct with anastomosis of the tubal artery and vein is described.  4 virgin female New Zealand white rabbits were used.  1 rabbit delivered a live litter of 9, 33 days following mating.  A 2nd rabbit is pregnant.  A third rabbit died 36 hours postoperatively due to prolonged anesthesia.  The graft proceeded uneventfully in the 4th rabbit, but the uterine cornu became infarcted because the uterine artery was ligated too far from its anastomosis with the tubal artery.  An advantage of a microsurgical technique for tubal and vascular anastomosis is that only the tube needs to be grafted, with minimal disturbance of the surrounding tissues.  In that healthy human fallopian tubes are readily available, it appears that this technique could be developed for homograft transplantation in patients with extensive oviduct disease.


Preparation of RNA transcripts of discrete segments of DNA.


Preparation, characterization, and activation of a highly purified factor XI: evidence that a hitherto unrecognized plasma activity participates in the interaction of factors XI and XII.


Prevention and treatment of carbon tetrachloride hepatotoxicity by cysteine: studies about its mechanism.


Procedure re-examined.

Procedure re-examined.


Proceedings: Bulgarian section for EEG and clinical neurophysiology.


Proceedings: Blockage of axoplasmic transport. Its relationships with the trophic function of neurons.


Proceedings: Carcinoma of the oral cavity--general principles of therapy.


Proceedings: Eastern Association of Electroencephalographers.


Presumptive Y-15 translocation and mental retardation in a family with a case of Klinefelter's syndrome.


Proceedings: Neurotrophic control of skeletal muscle of the rat.


Proceedings: Neurotrophic effects in relation to axoplasmic transport.


Proceedings: Polyclonal gammopathy and lymphoproliferation after transfer factor in severe combined immunodeficiency disease.


Proceedings: The EEG society.

Proceedings: The EEG society.


Proceedings: The effect of methoxy-derivatives of catecholamines on histamine release from sensitized human leucocytes and its inhibition by the parent compounds.


Proflavin-chymotrypsin interaction: high pressure temperature-jump studies.


Primate type-C virus-related reverse transcriptase and RNA in human acute leukemia cells as potential diagnostic markers.


Progress with antiviral agents.

Progress with antiviral agents.


Properties of factor 8 (antihemophilic factor).


Prolymphocytic leukaemia.

Prolymphocytic leukaemia.


Proportional mortality among vinyl-chloride workers.


Prospective, controlled trial of cyclophosphamide therapy in children with nephrotic syndrome. Report of the International study of Kidney Disease in Children.


Prostaglandin E2 and the stimulation of rat gastric acid secretion by dibutyryl cyclic 3',5'-AMP.


Protein phosphokinase activity in horse thyroid nuclei.


Protothecosis: a case of disseminated algal infection.


Proximal skin necrosis after radial-artery cannulation.


Pseudoxanthoma elasticum: dermal polyanions and the mineralization of elastic fibers.


Purification and properties of nitrate reductase from Escherichia coli K12.


Purification and detection of reverse transcriptase in viruses and cells.


Purification of human C3 proactivator by affinity chromatography.


Purification of the RNA-directed DNA polymerase from avian myeloblastosis virus and its assay with polynucleotide templates.


Purification, composition, and serological characterization of histoplasmin-H and M antigens. To obtain purified H and M antigens suitable as primary standards in the serological diagnosis of histoplasmosis by agar gel double-diffusion tests, H and M reactive components of histoplasmin were fractionated by column chromatography by using Sephadex G-100, Sephadex G-200, and diethylaminoethyl cellulose. Six fractions from diethylaminoethyl cellulose were reactive in agar gel double-diffusion, complement fixation, and capillary precipitin tests. When examined by electrophoresis on acrylamide gel, one M antigen (fraction 2, molecular weight greater than 200,000) and two H antigens (fractions 5 and 6, molecular weight greater than 200,000) each gave essentially a single protein band. In agar gel double-diffusion and complement fixation tests with sera from patients with proven cases of histoplasmosis, blastomycosis, or coccidioidomycosis, these two fractions of H antigen and the one of M antigen reacted only with sera from proven or suspect cases of histoplasmosis and showed reactivity with those sera known to contain only the anti-H or anti-M antibody, respectively. Fraction 2 (M antigen) and fractions 5 and 6 (H antigens) had carbohydrate-to-protein ratios of 1.60, 0.77 and 0.78, respectively. Both antigens contained galactose, glucose, mannose, and hexosamine, with mannose being the predominant sugar. Fraction 2 was characterized by a high proline and glucose content, whereas fractions 5 and 6 contained higher concentrations of galactose, mannose, glycine, and alanine. Each of these products appeared to separate into two active fractions, one of a molecular weight greater than 200,000 and one of a molecular weight less than 35,000. The M antigen component of fraction 2 was still characterized by a high proline content, whereas the H antigen components of fractions 5 and 6 had a high content of glutamic acid, serine, glycine, and proline.


Qualitative vitamin requirements of Oryzaephilus mercator fauvel and their deficiency effects on the survival and growth of F1-progeny.


Quantitative bone scanning: a method for assessing response of bone metastases to treatment.


Quantitative determination of secondary amines: measurement of N-methylalanine.


Quantity of serum immunoglobulins IgG, IgA and IgM in Bulgarian blood-donors.


Radial and axial gradients of lead concentration in bark and xylem of hardwoods.


Radioisotopes in preliminary screening of cervical cancer.


Rapid analysis of dichloran, lindane, PCNB and TCNB residues in lettuce by automated gas-liquid chromatography.


Radiozinc uptake and scintiscanning in prostatic disease.


Reciprocating supraventricular tachycardia initiated by paired premature beats.


Rapid fractionation technique and re-treatment of cerebral metastases by irradiation.


Reconstructive operations on mandible in children. (Clinico-experimental study).


Red cell hydrolases. 3. Neuraminidase activity in isolated human erythrocyte plasma membranes.


Regulation of expression of a cistron in the RNA bacteriophage MS2.


Reduction in circulating T lymphocytes in alcoholic liver disease.


Relation between viruses from acute gastroenteritis of children and newborn calves.


Relationship between Epstein-Barr virus (EBV) DNA and the EBV-determined nuclear antigen (EBNA) in Burkitt lymphoma biopsies and other lymphoproliferative malignancies.


Remnants of necrotic grey matter.

Remnants of necrotic grey matter.


Release of histamine from human skin induced by intracutaneous injection of adenosine-5'-triphosphate.


Replantation of composite graft of the nasal ala, Case report.


Respiratory mast cells and basophiloid cells. II. Effect of pharmocologic agents on 3'5'-adenosine monophosphate content and on antigen-induced histamine release.


Reverse transcriptase activity: increase in marrow cultures from leukaemic patients in relapse and remission. An enzyme activity with the characteristics of reverse transcriptase was detected in marrow from patients with leukaemia in relapse and in firm haematological remission. The endogenous enzyme activities increased following culture, and in remission patients the enzyme activities reached levels equal to or exceeding those found in relapse.


Reye's syndrome due to a novel protein-tolerant variant of ornithine-transcarbamylase deficiency.


Rhinophyma experiences with 81 operated patients.


Role of hepatitis-B antigen carriers in non-parenteral transmission of the hepatitis-B virus.


RNA-dependent DNA polymerase from avian myeloblastosis virus.


RNA-dependent DNA polymerase and ribonuclease H from Friend virions.


Sa 1, a possible new HL-A specificity found in the Japanese population.


Salivary gland rests in the human pituitary. Light and electron microscopical study.


Scientific medicine?

Scientific medicine?


Seasonal variation of histological osteomalacia in femoral-neck fractures.


Selective photoconvulsive responses to intermittent diffuse and patterned photic stimulation.


Senile cardiac amyloidosis in the dog.

Senile cardiac amyloidosis in the dog.


Senile changes in the fine structure of the lens in the rudd(Scardinius eryopthalmicus).


Sensitization of human lymphocytes against autologous or allogeneic lymphoblastoid cell lines: characteristics of the reactive cells.


Sensori-motor stimulation for the young handicapped child.


Separation and characterization of cortical and medullary bursal lymphocytes.


Sequential study of the impairment of thyroid function in the early stage of subacute thyroiditis.


Serology for automated cytotoxicity assays. Contrast fluorescence test.


Severe endemic trachoma in tunisia. II. A controlled therapy trial of topically applied chlortetracycline and erythromycin.


Alpha(1)-fetoprotein in chronic liver disease.


Simian sarcoma and feline leukemia virus antigens: isolation of species- and interspecies-specific proteins.


Simultaneous differential staining by a cationic carbocyanine dye of nucleic acids, proteins and conjugated proteins. I. Phosphoproteins.


Simultaneous differential staining by a cationic carbocyanine dye of nucleic acids, proteins and conjugated proteins. II. Carbohydrate and sulfated carbohydrate-containing proteins.


Soluble-complex formation after myocardial infarction.


Some aspects of sodium transport in chicken erythrocytes.


Some observations upon developmental dyslexia.


Some plastic operations in ophthalmology with use of sterilized homologous tissues.


Some psychoanalytic condiserations of bull fighting and bull worship.


Some practical aspects of the transfer of passive immunity to newborn foals.


Some questions of static tissue conservation theory.


Species responsible for the fluorescence of 1:N6-ethenoadenosine.


Specificity of hapten-reactive T and B mouse lymphocytes. Affinity and avidity of T- and B-cell receptors and anti-hapten antibodies as factors of dose and time after immunization.


Specificity of receptors for IgG on human lymphocyte-like cells.


Status quo in flow-through cytometry.

Status quo in flow-through cytometry.


Spectral matching of classical cytochemistry to automated cytology.


Structural and functional properties of blood monocytes cultured in vitro.


Structural change with pH of native beta-lactoglobulin A and B and of their derivatives with mercurinitrophenols as deduced from circular dichroic spectra.


Structural changes in chromaffin granules induced by divalent cations.


Studies of the direct coloring thiocholine method for localizing cholinesterase activity.


Some thoughts on nursing inservice education.


Studies on passive immunity in the foal. 1. Gamma-globulin and antibody variations associated with the maternal transfer of immunity and the onset of active immunity.


Studies on the binding and phagocytic inhibition properties of antimacrophage globulin (AMG).


Studies on the inhibition of C56 initiated lysis (reactive lysis). I. Description of the phenomenon and methods of assay.


Subacute toxicity of methylmercury in the adult cat.


Subcellular structure of bovine thyroid. VI. A study of bovine thyroid nuclei by density gradient centrifugation in a zonal A-XII rotor.


Submucous cleft palates.

Submucous cleft palates.


Successful laboratory screening for congenital hypothyroidism.


Studies of cochlear vasculature and sensory structures: a modified method.


Summary: the infant at risk--early detection and preventive intervention.


Superficial macromolecular arrays on the cell wall of Spirillum putridiconchylium. Electron microscopy of the cell envelope of Spirillum putridiconchylium, using negatively stained, thin-sectioned, and replicated freeze-etched preparations, showed two superficial wall layers forming a complex macromolecular pattern on the external surface. The outer structured layer was a linear array of particles overlying an inner tetragonal array of larger subunits. They were associated in a very regular fashion, and the complex was bonded to the outer, pitted surface of the lipopolysaccharide tripartite layer of the cell wall. The relationship of the components of the two structured layers was resolved with the aid of optical diffraction, combined with image filtering and reconstruction and linear and rotary integration techniques. The outer structural layer consisted of spherical 1.5-nm units set in double lines determined by the size and arrangement of 6- by 3-nm inner structural layer subunits, which bore one outer structural layer unit on each outer corner. The total effect of this arrangement was a double-ridged linear structure that was evident in surface replicas and negatively stained fragments of the whole wall. The packing of these units was not square but skewed by 2 degrees off the perpendicular so that the "unit array" described by optical diffraction and linear integration appeared to be a deformed tetragon. The verity of the model was checked by using a photographically reduced image to produce an optical diffraction pattern for comparison with that of the actual layers. The correspondence was nearly perfect.


Suppression of immunological memory for a cross-reactive idiotype in adult mice.


Surface antigens of murine IgM and IgG forming cells.


Surgical correction of alopecia;.

Surgical correction of alopecia;.


Susceptibility of rats to palmotoxins Bo and Go.


Suxamethonium--a review. Pharmacological actions of suxamethonium apart from its neuromuscular blocking effect.


Synaptic macromolecules: identification and metabolism.


Synthetic vaccines--a dream or reality.

Synthetic vaccines--a dream or reality.


Systemic anaphylaxis in the human being.


T cell recognition of cell surface antigens. I. Specificity.


Teaching blood morphology: audiovisual method compared to microscope slides with written text and instructor.


Systemic lupus erythematosus.

Systemic lupus erythematosus.


Techniques applicable to computer-aided cytophotometry in virology.


Techniques of open prostatectomy.

Techniques of open prostatectomy.


Temperature and weather correlates of myasthenic fatigue.


Template specificities of Xenopus laevis RNA polymerases. Selective transcription of ribosomal cistrons by RNA polymerase A.


Temperature effect on the permeability of plasma membranes of advanced germinal cells of the rat testis.


Testosterone metabolism in benign prostatic hypertrophy. Suppression by diethylstilbestrol and gestonorone capronate.


Textural parameters related to nuclear maturation in the granulocytic leukocytic series.


The activity and research programme of the tissue bank in Warsaw.


Tests for penicillin allergy in man. I. Carrier effect on response to penicilloyl conjugates.


The application of artificial intelligence techniques to biologic cell identification.


The argyrophil cells in the pancreatic islets of man.


The blue dextran excluded volume of the human erythrocyte membrane.


The cellular and molecular biology of RNA tumor viruses, especially avian leukosis-sarcoma viruses, and their relatives.


The chemical and immunologic properties of the basic A1 protein of myelin.


The chemical nature of the shell of molluscs. I. Prismatic and nacreous layers of a bivalve Lamellidans marginalis (Unionidae).


The chemistry and biochemistry of phytanic, pristanic and related acids.


The chemotherapy of colorectal cancer.

The chemotherapy of colorectal cancer.


The cytogenetic effect of triethylenemelamine in the rat as evaluated by the micronucleus test.


The cytophysiology of thyroid cells.

The cytophysiology of thyroid cells.


The definition of a lymphocyte-specific alloantigen system in the rat (Ly-1).


The early diagnosis of rejection by the leucocyte migration test in cadaveric renal transplantation.


The diagnosis of systemic lupus erythematosus.


The effect of fixation on staining of placental tissue.


The effect of antigen doses and time intervals between antigen injections on secondary, tertiary and quaternary antibody responses. Establishment of hyperimmunization with bovine serum albumin in mice treated with capsular polysaccharide of Klebsiella pneumoniae.


The effect of glycoprotein from Candida albicans on isolated rat mast cells.


The effect of post-heparin lipolytic activity on plasma lipoproteins. A study by electron microscopy.


The effect of sex, social class and parity on achievement of Denver developmental screening test items in the first year of life.


The effect of undernutrition on the rate of axonal transport in rabbit vagus nerves.


The effect of white noise on the somatosensory evoked response in sleeping newborn infants.


The effect of DL-lactate on regulation of porphyrin and heme biosynthesis in Escherichia coli and Achromobacter.


The effects of colchicine and lumicolchicine on the rapid phase of axonal transport in the rabbit visual system.


The effects of elevated intraocular pressure on slow axonal protein flow.


The effects of N-methyl-3 piperidyl benzilate (JB-336) on sleep pattern and spiking activity in the lateral geniculate nucleus.


The effects of 5,6-dihydroxytryptamine in the amphibian spinal cord using silver staining techniques.


The fibrillar proteins of nerve cells.

The fibrillar proteins of nerve cells.


The electronmicroscopy of DNA.

The electronmicroscopy of DNA.


The full thickness skin graft for primary repair of malignant facial tumours.


The fusion of hen erythrocytes by lipid-soluble and surface-active immunological adjuvants.


The genetics of C-type RNA tumor viruses.


The great protein fiasco.

The great protein fiasco.


The hormone synthesis of hyperfunctioning thyroid nodules in euthyroid patients.


The immunoglobulin system of the suckling pig.


The immune mechanisms and diagnosis of pigeon breeder's disease.


The infidelity of avian myeloblastosis virus deoxyribonucleic acid polymerase in polynucleotide replication.


The histochemical demonstration of O-acylated sialic acid in gastrointestinal mucins. Their association with the potassium hydroxide-periodic acid-schiff effect.


The influence of d-triiodothyronine (d-T3) on thyrotrophin secretion in man.


The interocular distance in children with cleft before the operation.


The investigation of superficial fungal infections by skin surface biopsy.


The isolation of glyco-alpha-lactalbumins from some ruminant milks.


The lack of correlation between hallucinogenesis and inhibition of axoplasmic transport.


The leukocyte migration test in atopic dermatitis.


The nitroblue-tetrazolium test following acute myocardial infarction. The percentage nitroblue-tetrazolium (NBT) leucocyte levels were evaluated daily in the 10 days following a first attack of coronary thrombosis. In 12 uncomplicated cases the peak increase was on the second or third day; thereafter the level declined and was below 10% by the tenth day. Three other patients did not conform to this pattern of NBT behaviour. They had experienced a second myocardial infarction and this was attended by a secondary rise in the NBT score; in the two survivors the score remained elevated on the tenth day. Comparison of the score on the second-third and tenth-fourteenth days is a possible useful index of a further complication.


The nuclear envelope: its ultrastructure and functional significance.


The naphthol yellow S stain for proteins tested in a model system of polyacrylamide films and evaluated for practical use in histochemistry.


The parenteral toxicity of clindamycin 2-phosphate in laboratory animals.


The pathology of the organic dementias.

The pathology of the organic dementias.


The pharmacodynamics of the oral anticoagulant drugs.


The preparation of RNA-directed DNA polymerase from ovaries of Xenopus laevis.


The metabolism of antifertility steroids. The in virto metabolism of chlormadinone acetate. The isolation and identification of the major in vitro metabolites of chlormadinone acetate are reported.  Human, rabbit, and rat liver incubations were employed in the isolation and identification, and male rat liver preparations were used to study the effect of phenobarbital stimulation on the formation of these metabolites.  The metabolic pathway was influenced by the microsomal stimulating property of phenobarbital.  2alpha-hydroxychlormadinone was the major metabolite from the incubation of phenobarbital-stimulated rabbit and male rat liver.  17alpha-acetoxy-6-chloro-3beta-hydroxypregna-4,6-diene-20-one was the major metabolite from the incubation of unstimulated human and male rat liver.  It was concluded that the 2alpha-hydroxychlormadinone acetate was demostrated only as a consequence of phenobarbital treatment.


The quantimet cytoscreen and the interactive approach to cancer screening.


The relation of red cell size to fetal hemoglobin concentration in the term infant.


The quaternary structure of alfalfa mosaic virus.


The role of soluble factors in T-B cell collaboration.


The response of the canine heart to double pulses of short duration: a simple addition principle.


The role of targets and mediators in endotoxin shock.


The significance of heart-reactive antibodies in heart disease.


The significance of Mallory bodies in the progression of fatty liver into cirrhosis.


The presence of melanocytes in the nasal cavity.


The structure of the fibrinogen degradation products.


The structure of a morphogenetic cytoplasm, present in the polar lobe of Bithynia tentaculata (Gastropoda, Prosobranchia).


The system bandpass required to avoid distortion of early components when averaging somatosensory evoked potentials.


The ultrastructure of cultivable treponemes. 1. Treponema phagedenis, Treponema vincentii and Treponema refringens.


The unlabeled antibody enzyme method of immunocytochemistry. Quantitative comparison of sensitivities with and without peroxidase-antiperoxidase complex.


The ultrastructure of human mitotic chromosomes and interphase nuclei treated by Giemsa banding techniques.


The use of coherent optical processing techniques for the automatic screening of cervical cytologic samples.


The use of dimethyl sulfoxide in assessing fertility in turkey eggs.


The use of fascial sling for the correction of postprostatectomy incontinence.


The use of germ-free piglets in the study of lymphoid tissue and germinal centre formation.


The use of protein A-containing Staphylococcus aureus as a solid phase anti-IgG reagent in radioimmunoassays as exemplified in the quantitation of alpha-fetoprotein in normal human adult serum.


The value of anti-DNA antibody titers in the early diagnosis, treatment and follow-up of systemic lupus erythematosus.


The Denver Developmental Screening Test. Achievement of test items in the first year of life by Denver and Cardiff infants.


The Sezary cell: cytologic, cytochemical, and immunologic studies.


The Hemalog D white cell differential system.


The Styx.

The Styx.


Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c.


Thrombophlebitis. A cardinal symptom of Behçet's syndrome.


Thymic dependence of amphibian antibody responses.


Thymus immunoglobulin receptors. Ontogenic development, response to antigenic stimulation and their possible role in the regulation of "aggressive" immune reactions.


Thyroid function after injury.

Thyroid function after injury.


Thyroid function in a prosimian, Perodicticus potto.


Thyroid-stimulating immunoglobulins in Graves' disease.


Thyrotrophin-releasing hormone in the treatment of depression.


Tissue banks and the problem of transplantation.


Tissue reactions after subcutaneous implantation of Hydron Sponge.


Tonic contraction of calf muscles by non-tetanic stimulation of popliteal nerve in man.


Total knee replacement.

Total knee replacement.


Toxic effects of warfarin in rats fed different diets.


Toxicologic changes in rats fed graded dietary levels of ochratoxin A.


Tracking the dominant frequency of the EEG by phase-locked loop demodulation.


Transformation of human fibroblasts with D.N.A. of cultured human rhabdomyosarcoma cells.


Transmission of Creutzfeldt-Jakob disease from man to squirrel monkey.


Transplantation of homogenous joints. Treatment of homogenous osteocartilaginous graft by partial replacement for autogenous cancellous bone and impregnation with autogenous marrow.


Treatment of immediate hypersensitivity reactions to drugs.


Tuberculin sensitivity in BCG-vaccinated children with common warts.


Treatment of oat-cell carcinoma of bronchus by preoperative radiotherapy and surgery.


Tumors formed by human rhabdomyosarcoma cells in chorioallantoic membrane of embryonated hens' eggs.


Two propylhexedrine-associated fatalities: Benzedrine revisited.


Typing of Haemophilus influenzae by counterimmunoelectrophoresis.


Ultrastructural evidence for myosin of the smooth muscle type at the surface of trypsin-dissociated embryonic chick cells.


Ultrastructural differences along the colonic mucosa of the mouse.


Ultrastructure and organization of the bacterial envelope.


Ultrastructure of cells isolated from rabbit aorta.


Ultrastructure of freeze-cleaved dermal collagen.


Unblocking or activation of the cellular immune mechanism by induced proteolysis in patients with cancer.


University of Birmingham educational services unit.


Unbuffered osmium staining in pars recta of the proximal tubule from rat kidney studied by thin and semi-thin section cytochemistry.


Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders.


Use of a spectral ratio in lateralization of CNS lesions.


Use of antibiotics in a dairy herd and their effect on resistance determinants in enteric and environmental Escherichia coli.


UDPG-glycogen transferase and phosphorylase activities in isolated rat liver parenchymal cells.


Vaccinia of the vulva. A case report.

Vaccinia of the vulva. A case report.


Value of new laboratory tests in diagnosis and treatment.


Value of the combined cytological and cytochemical classification in the management of acute childhood leukemia.


Variations in separation-individuation and implications for play ability and learning as studied in the three-year-old in nursery school.


Variation in the pattern of carbonic anhydrase activity in the cells of the gastric glands.


We need medical superintendents.

We need medical superintendents.


Viroimmunoassays: detection of virus-antigen-antibody complexes with an immunoadsorbent.


William Gordon Masefield.

William Gordon Masefield.


Whooping-cough vaccination. An assessment.


William James McCracken.

William James McCracken.


Yolk sac tumor and alpha-fetoprotein: clinicopathological study of four cases.


"Genetic' transformation of bacteria by RNA and loss of oncogenic power properties of Agrobacterium tumefaciens. Transforming RNA as template for DNA synthesis.


in vitro studies on allotype suppression. I. Release from allotype suppression by antibodies specific for the non-suppressed allotype.


o-Phthaldialdehyde reactive substances in dog's plasma and gelatin (Haemaccel) complicating the determination of histamine.


[Phytohemagglutinin-induced increase of euchromatin contents in human lymphocytes].


A case of congenital toxoplasmosis with active chorioretinitis. Parasitological and histopathological findings.


A case of sex-linked hereditary dysgammaglobulinaemia accompanied by interstitial pneumonia and lasting neutropenia.


A cellular basis for auto-immunity.

A cellular basis for auto-immunity.


A clinical and histopathological study of twenty-seven cases of Urbach-wiethe disease. Dermatologic, gastroenterologic, neurophysiologic, ophthalmologic and roentgendiagnostic aspects, as well as the results of some clinico-chemical and histochemical examinations.


A comparative immunochemical study of Shigella sonnei haptene polysaccharides.


A histological evaluation of peripheral nerve repairs.


A double blind trial of a polyene macrolide--nystatin--in the treatment of benign prostatic hyperplasia in man.


A histopathological report on the nature of the epithelium and underlying connective tissue which surrounds oral implants.


A light and electron microscopic study of the adenomatoid odontogenic tumor.


A method for the mathematical study of the stained mass of the chromosomes.


A micro procedure for fast typing of the genetic variants of phosphoglucomutase.


A microculture technique utilizing whole blood for mouse chromosome analysis.


A new method for identification of individual nephrons for light and electronmicroscopy.


A new group of oncornaviruses.

A new group of oncornaviruses.


A new polysaccharide antigen common to Staphylococcus aureus strains of bacteriophage type 187.