Further observations on the blood vessels of skeletal muscle (rat cremaster).


Notes on the Marchi method for staining degenerating myelin in the peripheral and central nervous system.


Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.


Congenital pain asymbolia and auditory imperception.


Studies on the formation of hyperplastic focus by variola virus in human cell cultures. I. In vitro quantitation of variola virus by focus counting in HeLa and FL cell cultures.


The dense bodies of human platelets. Origin of serotonin storage particles from platelet granules.


Introduction of intravascular coagulation and focal tissue necrosis in rats by administration of anti-connective tissue antibodies.


The palliation of mitral stenosis.

The palliation of mitral stenosis.


Human renal allografts. Interpretation of morphologic and immunohistochemical observations.


Granular cell myoblastoma. A histological and enzymatic study.


Some properties of the virus od duck plague.


Effect of pyronin Y on adenovirus.

Effect of pyronin Y on adenovirus.


Secondary methylation of ribosomal ribonucleic acid in HeLa cells.


Maturation of dental enamel in germfree and monoinfected Sprague-Dawley rats.


Immunoglobulin E, a new class of human immunoglobulin.


Ribonucleic acids from animal cells.

Ribonucleic acids from animal cells.


Microscopic lesions in the brain following head injury.


Effects of pre-eclampsia on the changes in iodine metabolism during pregnancy.


Transformations of Rorschach content under two hypnotic trance levels.


Some morphological observations on the leucocytes of immature leukaemias in short-term in vitro culture.


Histochemical studies of glucose-6-phosphatase activity in parenchymal cell damage on the liver of rats fed on 4-dimethylaminoazobenzene.


The humanness of human beings: psychoanalytic considerations.


Experimental tobacco carcinogenesis.

Experimental tobacco carcinogenesis.


New developments in educational technology. AAAS Symposium December 1968 Dallas, Texas.


Genetic polymorphism of C'3(beta1C-globulin) in human serum. Genetic polymorphism of the third component of human complement and its breakdown products has been detected in human serum by high-voltage starch-gel electrophoresis. Six phenotypes were observed in a study of 113 randomly chosen Caucasians. Their inheritance is controlled by four codominant alleles at an autosomal locus. The gene frequencies in this study were C3(1), 0.21; C3(2), 0.77; C3(3), approximately 0.01; and C3(4), approximately 0.004.


Serological and immunochemical characterisation of the Lima bean anti-A lectin.


Estimation of fetal maturity by cytologic examination of amniotic fluid.


Management of recurrent carcinoma of the cervix.


Language as a symbolic process in communication. A psychological perspective.


Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.


In vivo staining of the parathyroid glands. A clinical study.


Preparation of highly purified human thyroglobulin.


Homologies in the primary structure of immunoglobulin heavy chains from different animal species.


Practical demonstrations.

Practical demonstrations.


Crystallographic studies of a human immunoglobulin.


Hidden antigenic determinant in secretory immunoglobulin A.


Induction of a unique fluorescence in the photoreceptor of the retina.


Effect of poly-L-arginine on rate of bovine IgG transport by newborn pig intestine.


Alteration of plasma proteins during extracorporeal circulation. I. Experimental studies with 131-I-labelled plasma protein fractions.


Changes in erythrocyte sedimentation rate and serum proteins during experimentally produced erysipelatous arthritis in swine. The changes in the percentage of serum proteins and erythrocyte sedimentation rates in 14 swine given weekly injections of Erysipelothrix insidiosa or other antigens were studied. A sharp rise in the erythrocyte sedimentation rate and in the percentage of alpha globulin occurred at the seventh day after the first injection in seven of the eight pigs which received the viable cultures. The erythrocyte sedimentation rate and percentage of alpha globulin then returned to normal. Later, as arthritis developed, the erythrocyte sedimentation rate again increased, but this time the increased rate was accompanied by an increase in the percentage of gamma globulin. The erythrocyte sedimentation rate and percentage of serum proteins remained virtually unchanged in the three animals which were given dead erysipelas organisms and in the three animals which were given culture medium alone.


Basic considerations in chemotherapy of gynecologic cancer.


Treatment of ovarian cancer with thiotepa.


Immunofluorescent studies on renal biopsies in pregnancy.


Psychoanalytic method in psychosomatic research.


Severe bodily illness in childhood.

Severe bodily illness in childhood.


Treatment of oral malignancies by radiotherapy.


Electrophoretic separation of plasma lipoproteins in agarose gel. A method has been developed for the separation of serum or plasma lipoproteins by electrophoresis in an agarose-agar gel mixture. The gel is applied to the surface of a thin polyester photographic film strip. With minor alterations in technique either single samples on individual strips or many samples on one large sheet may be processed. After fixation and dehydration the transparent film is stained with Sudan Black B and washed with water. The finished electrophoretogram can be obtained in 5 hr and consists of widely separated bands of lipoprotein fractions on a colorless transparent background, ideally suited for scanning with a densitometer. Plasma samples from different subjects show pre-beta lipoproteins of different mobilities. An effect of gel concentration on the extent of lipoprotein migration is demonstrated. The clearcut separation of lipoproteins by this method will facilitate the classification of hyperlipoproteinemias and improve quantitative estimates of lipoprotein distribution.


Blast from the back room.

Blast from the back room.


Chronic ischaemic myelopathy in aortic atherosclerosis.


The development of basal bodies in paramecium.


Chemical and physical fixation of isolated mitochondria in low-energy and high-energy states.


The fine structure of the cerebroside occurring in Gaucher's disease.


Child psychiatry.

Child psychiatry.


Lymph flow and protein composition of thoracic duct lymph in the newborn calf.


Osteoplastic thoracoplasty as palliative treatment of thoracic deformity in scoliosis.


Ontogeny of the mouse immune system: immunoglobulin producing cells. USNRDL-TR-68-57.


Levels of the serum immunoglobulins gamma-A, gamma-G and gamma-M in the malabsorption syndrome in children.


Sodium retention after adrenal enucleation: drug and salt appetite studies.


Clonal growth of differentiated rabbit cartilage cells.


Investigations on gastrointestinal protein loss in the nephrotic syndrome.


Precision of anatomic mensuration from roentgenograms: a cystourethrographic study.


Preparation and clinical use of antilymphocyte globulin.


Uncoiling of bacteriophage-phi X174 replicative form deoxyribonucleic acid by ethidium, daunomycin and actinomycin.


Effect of immunization on serum protein levels in the horse.


Nucleolar 4s ribonucleic acid in dipteran salivary glands in the presence of inhibitor. 1. Salivary glands of insect larvae accumulate newly made transfer RNA in the nucleolus when maintained in the presence of nucleoside antagonists that inhibit RNA synthesis preferentially at the chromosome. 2. The nucleus contains precursor transfer RNA, which, on the basis of the general evidence, may originate in the chromosome and then be methylated in the nucleolus. 3. The maturation of precursor ribosomal RNA is blocked in the nucleolus during inhibition. 4. The transport of nuclear RNA to cytoplasm is also blocked. 5. It is suggested that, if the transfer RNA accumulated in the nucleolus does indeed originate in the chromosome, the accumulation may result from the blockage of an obligatory transient association of the RNA with the nucleolus.


Spinal electrogram of the cat. I. Study of origin by degeneration and ischemia.


Thyroid hormone and brain function. IV. Effect of triiodothyronine on visual evoked potentials and electroretinogram in man.


Spinal electrogram of the cat. II. Supraspinal influences.


Evoked responses as a function of external and stored information.


Electroencephalographic features in posterior fossa tumors in children.


Study on 14 and 6 per second positive spikes during nocturnal sleep.


Synchronized spindle activity elicited in the cortex of the monkey by basal ganglia stimulation.


Acoustic responses in the hypothalamus.

Acoustic responses in the hypothalamus.


Zero crossing detection of the presence of evoked responses.


Continuous EEG and EMG recordings during night sleep in a case of subacute sclerosing leucoencephalitis.


Assessing the significance of averaged evoked potentials with an on-line computer: the split-sweep method.


An automatic temperature control apparatus for micro-electrode techniques.


A transistor amplifier for chronic micro-electrode recording.


A re-usable nylon socket holder for use with chronically embedded electrodes in the cat.


Studies of the EEG activity of limbic structures in man.


The effects of attention and distraction on the contingent negative variation in normal and neurotic subjects.


Responsivenessof the cortex and visual pathway during transient hypotension.


Cortical excitability patterns in the cat: effects of cortical and subcortical lesions.


Effect of lesions of the ventro-medial hypothalamus on the electrical activity of the ventro-lateral hypothalamus.


Development of electroencephalographic sleep phenomena in hypothayroid infants.


Cerebellum and hyperbaric oxygen.

Cerebellum and hyperbaric oxygen.


Subjective and EEG responses to LSD in visualizer and non-visualizer subjects.


Serial EEGs of patients with Parkinsonism-dementia syndrome of Guam.


Feedback mechanisms controlling voluntary and reflex movements.


Error reduction in small sample averaging through the use of the median rather than the mean.


Pulse generator with external amplitude control by computer.


Electroencephalographic patterns in pellagra.


Cerebral control of movement.

Cerebral control of movement.


The spinal nervous organization in man.

The spinal nervous organization in man.


Influence of spino-cerebellar pathways on the cerebellar control of spinal motoneurones.


EMG studies of gait in man.

EMG studies of gait in man.


Accelerometric and EMG study of movements and tendon reflexes.


EMG analysis of a rapid volitional movement.


Kinesiological basis of rehabilitation of paralysed limbs: problems raised by controlling movements.


Control of release phenomena in hemiplegics by means of afferent electrical stimulation.


Electrophysiological observations of reflex motor functions in hemiparetic patients following long-term application of the external control of paretic muscles.


Influence of the termination of movement on the relationship between the mechanical work and the integrated EMG of the principal agonist.


The decompression reflex of patients with Parkinson's disease before and after stereotaxic operations, and after pharmaceutical treatment.


Motor unit control.

Motor unit control.


EMG analysis of myasthenic phenomena during the early deterioration and the improvement following ACTH treatment.


The staircase phenomenon in normal and in myasthenic human muscle.


The neuro-muscular defect in human botulism.


Persistent neuro-muscular block after curarization in tetanus.


The influence of normal human serum and its ultrafiltrate on neuro-muscular transmission.


A case of peripheral polyneuropathy displaying myasthenic EMG patterns.


Radial nerve conduction studies, an improved technique.


Electrophysiological investigation in radial nerve palsy.


Posterior tibial nerve conduction in man.


Differences in maturation of conduction velocities for the nerves of upper and lower extremities.


Electrical and morphological observations on uraemic neuropathy.


Femoral nerve conduction in diabetes mellitus and chronic occlusive vascular disease.


The peripheral neuropathy of Friedreich's ataxia.


Experimental neuropathy in rats made diabetic with alloxan.


The effect of local pressure in diphtheritic neuropathy.


Compound action potentials of human sural nerve biopsies.


Motor unit size in large and small muscles: some observations on the baboon.


Choice of electrode, amplifer and auxiliary equipment for the recording of muscle and nerve action potentials in man.


Problems in the recording of electrically and voluntarily evoked potentials.


The parametric pre-amplifier.

The parametric pre-amplifier.


Quantitative analysis of the EMG.

Quantitative analysis of the EMG.


Automatic measurement of some EMG parameters.


Quantitative EMG as a method of carrier detection in X-linked muscular dystrophy.


Application of cross-correlation analysis of interferential EMGs to the study of time relations of motoneurone discharges in man.


How to evaluate variations in muscle action potentials following repeated nerve stimulation.


Automation EMG analysis, a new approach.


Dynamic frequency analysis of myo-potentials.


The development of EMG under voluntary and postural innervation (reflex- and needle-EMG).


Polyphastic motor unit action potentials.


Spontaneous electrical activity in human muscle.


End-plate noise.

End-plate noise.


EMG findings on re-innervation in peripheral nerve lesions.


EMG in patients with so-called parietal atrophy.


EMG study of two cases of von Eulenburg's congenital paramyoonia.


Causes of abnormal sensory potentials in neuropathy.


Static and dynamic components in the responses of muscle spindles to stretch, and their role in muscle control.


The structure and innervation of mammalian muscle spindles.


The behaviour of isolated mammalian muscle spindles with intact innervation.


The response of primary and secondary afferents from muscle spindles to sinusoidal mechanical stimulation.


Motor effects of muscle vibration in spasticity, rigidity and cerebellar disorders.


Mechnoreceptor activity recorded from human peripheral nerves.


The effect of vibration on afferent nerve conduction and spinal reflex mechanisms.


Changes in motoneurone excitability produced by sudden ankle movement.


Alterations in the dynamic and static properties of the stretch reflex obtained at various rates of stretch during different stages of clinical spasticity.


Corrales M: Electrically and mechanically induced reflex responses in spasticity and influence of Valium and related drugs.


Blink reflex test.

Blink reflex test.


An EMG study on the late reflex component (nociceptive) of the orbicularis oculi muscle.


EMG tracing of extraocular muscles in man.


An instrument for the measurement of msucle responses to low frequency vibration.


Bell's palsy.

Bell's palsy.


Contralateral re-innervation in facial palsy.


Electroneurographic studies in chronic vitamin E deficiency.


Diagnostic value of EMG in partial and in total ruptures of the Achilles tendon.


Effect of diphenylhydantoin on peripheral nerves in man.


Micro-electrode study of normal and dystrophic human muscle.


EMG in treated Cushing's syndrome with particular reference to the post-adrenalectomy syndrome.


EMG study of Turner's syndrome.

EMG study of Turner's syndrome.


The EMG test in the study of pseudo-hypoparathyroidism and pseudo-pseudo-hyparathyroidism.


The effect of ischaemia on neuro-muscular transmission in individual motor end-plates in man.


The effect of non-paralytic doses of neuro-muscular blocking drugs on the transmission in individual motor end-plates in man.


EMG phenomena in the "stiff-man" syndrome.


Myasthenic reaction in primary muscle fibre disease.


Electrodiagnosis of polyneuropathy.

Electrodiagnosis of polyneuropathy.


Car driving aptitude evaluation: an EMG contribution.


EMG findings in a case of McArdle's myopathy.


Value of the EMG in the diagnosis of a cardiomyopathy associated with a myotonic myopathy.


Studies on human muscle contraction and on the staircase phenomenon.


Sensory nerve conduction velocity in neuropathies, as estimated from cerebral evoked potentials.


Correlations between aldolasaemia and motor unit territory in the evaluation of Duchenne's progressive muscular dystrophy.


Oculo-pharyngeal muscular dystrophy in six siblings with paradoxical EMG findings.


Rheoencephalographic study of two cases of subclavian steal syndrome.


The amplitude of the alpha rhythm in the left and right occipital areas in the EEG's of normal subjects and in post-cocussional syndromes.


Rheoencephalographic study of some vasodilator drugs. Preliminary note.


On the reflex epilepsies: epilepsy caused by reading.


Statistical approach to correlations between clinical and EEG data in neurosis.


Possible influence of pre-natal irradiation on the development of cerebral electrical activity in man.


Site of prolactin in the pituitary gland, as studied by immunofluorescence.


Freezing-induced alterations in thyroglobulin from iodine deficient and iodine sufficient rats.


Studies on the immunological properties of LATS.


Anaphylactic histamine release from guinea pig basophil leucocytes; basophil leucocyte anaphylaxis.


Action of the histamine sensitizing factor from Bordetella pertussis on inbred and random bred strains of mice.


The normal microbial flora as a major stimulus for proliferation of plasma cells synthesizing IgA in the gut. The germ-free intestinal tract.


Purification of beta-glucosidase from Saccharomyces lactis strain Y-123. Saccharomyces lactis strain Y-123, a constitutive high producer of beta-glucosidase (B(h)), was grown in an enriched medium. beta-Glucosidase, extracted most easily by cell autolysis, was purified by successive ammonium sulfate precipitation, ethyl alcohol precipitation, gel filtration, calcium phosphate gel adsorption-elution, and hydroxyapatite column chromatography. The specific activity of the enzyme increased 200-fold during the purification. The electrophoretic and catalytic properties of the enzyme did not change during the procedure. Polyacrylamide gel disc electrophoresis of the partially purified enzyme revealed one major and several minor protein-staining bands. beta-Glucosidase activity in the polyacrylamide gel columns was measured directly by assaying sections of columns frozen and sliced immediately after electrophoresis. Most of the activity coincided with the major protein-staining band. Prolonged assay produced minor activity coinciding with the less intense protein bands. Properties of the enzyme suggest that it is a single, unconjugated, intracellular, high molecular weight protein. The purification procedure is applicable to strains of S. lactis which possess alleles of the B locus for beta-glucosidase synthesis.


Intranuclear growth of Rickettsia rickettsii.


Surface antigens of smooth brucellae.

Surface antigens of smooth brucellae. Surface antigens of smooth brucellae were extracted by ether-water, phenol-water, trichloroacetic acid, and saline and examined by immunoelectrophoresis and gel diffusion with antisera from infected and immunized rabbits. Ether-water extracts of Brucella melitensis contained a lipopolysaccharide protein component, which was specific for the surface of smooth brucellae and was correlated with the M agglutinogen of Wilson and Miles, a polysaccharide protein component devoid of lipid which was not restricted to the surface of smooth brucellae and was not correlated with the smooth agglutinogen (component 1), and several protein components which were associated with internal antigens of rough and smooth brucellae. Immunoelectrophoretic analysis of ether-water extracts of B. abortus revealed only two components, a lipopolysaccharide protein component, which was correlated with the A agglutinogen, and component 1. Component 1 from B. melitensis and B. abortus showed identity in gel diffusion tests, whereas component M from B. melitensis and component A from B. abortus showed partial identity with unabsorbed antisera and no cross-reactions with monospecific sera. Attempts to prepare monospecific sera directly by immunization of rabbits with cell walls or ether-water extracts were unsuccessful. Absorption of antisera with heavy fraction of ether-water extracts did not always result in monospecific sera. It was concluded (as has been described before) that the A and M antigens are present on a single antigenic complex, in different proportions depending upon the species and biotype, and that this component is a lipopolysaccharide protein complex of high molecular weight that diffuses poorly through agar gel. Components 1, A, and M were also demonstrated in trichloroacetic acid and phenol-water extracts. With all extracts, B. melitensis antigen showed greater diffusibility in agar than B. abortus antigens. After mild acid hydrolysis, B. abortus ether-water extract was able to diffuse more readily.


Lysosomes of Toxoplasma gondii and their possible relation to the host-cell penetration of toxoplasma parasites. Lysosome-like structures of Toxoplasma gondii were observed by means of vital staining with acridine orange and by the Gomori technique. These structures were found scattered over the cytoplasm but were often located at one end of the parasite. In comparison with parasites of the inoculum used for infecting HeLa cell cultures, the toxoplasma which had penetrated the HeLa cells revealed a markedly lower percentage of parasites showing lysosomal staining. After the penetration, the number of parasites with demonstrable lysosomes increased successively and, at the time for release of newly formed parasites (at 24 hr), the majority of the parasites demonstrated lysosome-like bodies in the cytoplasm. The observations are discussed with special reference to the mechanism of host-cell penetration.


Heterogeneity of antibody response to Salmonella lipopolysaccharide measured by passive hemagglutination and hemolysis in mice. The complement-requiring passive hemolysis test with Salmonella typhimurium lipopolysaccharide-coated sheep erythrocytes is more sensitive for antibodies directed against the lipopolysaccharide than is the passive hemagglutination test. The hemagglutinating and hemolyzing antibodies produced in Swiss mice by hyperimmunization, either with or without Freund's adjuvant, were distributed in both the light and heavy fractions isolated by sucrose density gradient fractionation and gel filtration. IgM fractions, whether tested by hemagglutination or hemolysis, were sensitive to 2-mercaptoethanol (0.15 m). On the other hand, IgG hemolytic antibodies were more sensitive to 2-mercaptoethanol than were IgG hemagglutinating antibodies. The resistance of IgG hemagglutinating activity amounted to about 72 to 95% of the total IgG recovered, whereas the resistant portion of the IgG hemolytic activity was approximately 40 to 53%. It is suggested that, although mercaptoethanol sensitivity is not a definitive test for IgM antibody, its use in connection with the hemagglutination test gives at least an approximation of the IgG antibody, whereas the hemolysis test gives a better approximation of maximal measurable antibody against Salmonella lipopolysaccharides.


The responses of the basophil leucocyte.


The metabolism of "histidine-rich" protein in normal and psoriatic keratinization.


The preferential extraction of keratohyalin granules and interfilamentous substances of the horny cell.


Some reticuloendothelial cells in the white pulp region of the rat spleen.


Antigen-induced inhibition of cell migration in agar gel, plasma clot, and liquid media.


Cryotherapy as a palliative maneuver.

Cryotherapy as a palliative maneuver.


Degos' disease (malignant papulosis). Report of three cases with clues to etiology.


Proximal axonal enlargement in motor neuron disease.


Arthrogryposis multiplex congenita. Report of two cases of a radicular type with familial incidence.


Infantile neuroaxonal dystrophy. A disease characterized by altered terminal axons and synaptic endings.


The use of Nile blue sulphate in the histochemical identification of phospholipids.


Selective staining of endocrine cells by basic dyes after acid hydrolysis.


The changes in fluorescence of acridine orange-stained HeLa cells during ultraviolet illumination.


An evaluation of preparatory procedures for leaf-tip chromosomes spreads of the tea plant (Camellia sinensis).


Staining isolated proteins and polysaccharides on slides; phosphotungstic acid-hematoxylin versus the rosindole reaction.


Formalin fixation of cultured cells in their growth medium; giemsa staining.


Nigrosin-Hg-Cl2-formalin; a stain-fixative for ciliates (Protozoa, Ciliophora).


Bicarbonate and chloride shifts in rat brain during acute and prolonged respiratory acid-base changes.


Fatty acid composition of a fresh-water carp, Scardinius erythrophtalmus L.


Facilitation of monosynaptic reflexes in the spinal cord of the frog.


The influence of thyroid hormone on myocardial contractility.


Generation of membrane potentials in lepidopteran muscle. II. The effect of ionic depletion on resting and action potentials.


Activity of delta 5-3 beta-hydroxysteroid dehydrogenase in rat adrenals in the early postnatal period.


The pattern of respiratory compensation in chronic metabolic acidosis.


Staircase potentiation in normal human muscle: instantaneous relation between force and speed of the twitch.


Driving of single motor units in the human by rhythmical stretch of the muscle.


Clearances of IRI and NSILA in bile before and after glucose injection in normal dogs.


Post-tetanic repetitive activity in single human motor axons.


Physico-chemical properties of catecholamine granules and mitochondria from adrenal medulla.


The 5'-terminal tetranucleotide sequence of bacteriophage MS2 ribonucleic acid.


Study of phosphorylase and its regulating enzymes in the embryonic chick liver.


Bacteriophage MS2 induced proteins.

Bacteriophage MS2 induced proteins.


Purification and properties of a neutral protease from alf thymus nuclei.


The efferent connexions of the olfactory bulb in the frog: a study of degenerating unmyelinated fibres.


Anti-tuberculosis chemotherapy in Australia.


Some apparently common problems in patients receiving contraceptive pills.


Diffuse glomerulonephritis associated with infected ventriculoatrial shunt.


The cleft patient theory and dental responsibility.


Congenital hypothyroidism with impaired thyroid response to thyrotropin.


A porte in a storm.

A porte in a storm.


Random thoughts on establishing a practice.


Effect of tetracycline on osteogenesis in vivo.


Multiple myeloma.

Multiple myeloma.


An evaluation of several American and foreign dental journals.


Addendum to the History of Dentistry in Pennsylvania. Early History of the 4th District Dental Society.


To the Editor: "Dentistry's exclusion from the Medical Complex at Hershey, Pa.--A serious omission.


Veterans administration--Pennsylvania revised dental fee schedule--effective July 1, 1968.


Serum proteins after splenectomy in the dog, the rabbit and the rat.


Passive cutaneous anaphylaxis in chickens.


The occurrence of plaque forming cells in normal and immunized conventional and germfree mice.


Role of liver in the inactivation of interferon.


Further studies on serum protein formation by chimeras. I. Effect of cytotoxic agents on serum protein formation.


Germ cell migration in rats carrying mutant tenes affecting fertility.


Enzyme activities in the germinal layer of normal and psoriatic human skin.


Keratinosomes in psoriatic skin.

Keratinosomes in psoriatic skin.


Delayed dermal and epidermal reactivity in atopic dermatitis (prurigo Besnier). 3. Further studies with bacterial and viral allergens.


Delayed type of allergy and atopic disease among twins.


Antinuclear factors, rheumatoid factors and Bordet-Wassermann reaction in chronic and systemic lupus erythematosus.


Studies of the mechanism of ultra-violet erythema formation. V. Changes in the fine structure of mast cells of the skin during the process of ultra-violet erythema caused by waveband UV-C.


Rubber bank note counters as the cause of eczema among employees at the Swedish Post Giro Office.


Serum lactate dehydrogenase patterns and arginosuccinic aciduria in ordinary alopecia areata and alopecia diffusa.


Erythema induratum Bazin. Incidence and views on aetiology related to the presence of an immigrant population in London.


Epidermolysis bullosa hereditaria. I. Epidermolysis bullosa hereditaria letalis. A survey of the literature and report of 11 cases.


Dermatophytes isolated from an open air public bath.


The limitations and usefulness of pH-indicators in the classification of dermatophytes.


Familial granuloma annulare.

Familial granuloma annulare.


Topical triamcinolone acetonide and chlorhydroxyquinoline in acne.


The activity of cathepsin B in human fetal skin.


Experimental under-treatment of early syphilis with probenecid and penicillin in anti-gonorrhoea dosages. A study to assess the best follow-up examination time for syphilis after gonorrhoea treatment in Greenland.


Serum immunoglobulin levels in syphilis.


Gonorrhoea in 1966. Cases treated at the Department of Dermatology, Karolinska Sjukhuset.


Electron-microscopic search for virus particles in patients with leukemia and lymphoma.


Fine structure and surface adenosinetriphosphatase activity of a human hepatoma.


Indications for and resuls of irradiation of carcinoma of the lung.


Colonic histiocytosis: clinical and pathological evaluation.


Humane exposure to lindane; blood lindane levels as a function of exposure.


C-terminal sequence of the F'c fragment of human gamma G globulin.


Some problems raised by the ISf systems of human immunoglobulins.


Cold haemagglutinins associated with splenomegaly in New Guinea.


Effects of a sequential oral contraceptive on endometrial enzyme and carbohydrate histochemistry.


In vitro autoradiographic study of the endometrium from women treated with low-dose chlormadinone acetate for contraception.


Urinary dynamics in benign prostatic hypertrophy.


Trichomomas vaginalis in gram-stained smears.


Preparation of fluorescein-labelled immune globulin for the identification of Treponema pallidum.


Blood trasketolase and erythrocyte glucose-6-phosphate dehydrogenase activities in thyrotoxicosis.


Defective (incomplete) synthesis of immunoglobulin heavy polypeptide chains as the cause of a myeloma-like disease.


A new histochemical stain for neutrophilic leukocyte alkaline phosphatase.


Effect of ascorbic acid on oral healing in guinea pigs.


The use of formvare membrane for study of some cytophysiological parameters of pollen grains.


Plastic surgery nursing at Canniesburn Hospital, Bearsden.


Electrophoretic analysis of antibody produced by single cells.


Chain models of 6.6S and 3.9S mouse myeloma gamma A immunoglobulin molecules.


Perivascular infiltration in brain biopsy and autopsy material in subacute sclerosing panencephalitis. (Immunopathological study).


The organochlorine insecticide content of human tissues.


A nucleus in the dorsolateral funiculus of the spinal cord of the rat.


The projection of the somatic sensory cortex upon the thalamus in te cat.


The lateral cervical nucleus in the cat. I. A golgi study.


Symbolization and symbolic thought: response to Furth.


Demonstration of inclusion bodies in the musculature of patients with muscle sarcoidoses and polymyositis.


The effect of KC1, NaC1, hydration and dehydration on the subcommissural organ of the domestic pigeon.


The thyroid-regulating habenular mechanism and the thyrotrophic aree of the anterior hypothalamus.


Studies on the blood--thymus barrier.

Studies on the blood--thymus barrier.


The fine structure of abdominal paraganglia in the newborn mouse.


Changes in the activity of the central nervous system of Anodonta cygnea upon the action of chemical agents.


Circadian fluctuation in plasma proteins of the rat.


Primary amyloidosis.

Primary amyloidosis.


The gamma globulin content of meconium and amniotic fluid and the intestinal immunity of the newborn to poliovirus.


2-amino-6-(methylthio)caproic acid, a methionine homolog and precursor of pogoitrin.


Von Willebrand's disease--diagnostic criteria.


Dysgammaglobulinaemia in tropical sprue. Study of immunoglobulin levels in 16 Indian control subjects showed that, compared with a Danish control series, they had a significantly higher mean level of IgG, but not of IgA or IgM. By contrast, the IgG levels in eight patients with tropical sprue were decreased or low normal in six cases and raised in only one case. Two patients with tropical sprue had agamma-A-globulinaemia.Turnover studies with (125)I-labelled IgG showed a high rate of synthesis in three Indian controls and an appreciably reduced or low rate in seven of the eight cases of tropical sprue.


Regulation of glycolysis in human red cells.


The concentration of some nucleotides and glycolytic metabolites in human erythrocytes of different ages.


Glycolysis in shrunken and swollen erythrocytes.


Binding of ATP and 2,3-DPG to hemoglobin-effect on erythrocyte glycolysis.


Interaction of pentose and hexose pathways in human erythrocyte ghosts.


Formation of extracellular adenosine triphosphate by human erythrocytes.


Studies on the mechanism maintaining biconcave shape of human erythrocytes.


The decrease of red cell ATP and activation of red cell membrane adenosine triphosphatase due to the immune injury of the erythrocye membrane.


A quantitative approach to the detection of nuclear activity after differeetial damage to nucleus and cytoplasm in early development.


Staining axons in normal and abnormal teased peripheral nerves.


Effect of ethyloestrenol combined with phenformin or with metformin on platelet stickiness and serum-cholesterol in patients with occlusive vascular disease.


The Aberdeen junior houseman year.

The Aberdeen junior houseman year.


Encephalopathy after portacaval anastomosis.


Maternal radiation and chromosomal aberrations.


Sucrose intake and coronary heart-disease.


The motor-scooter-handlebar syndrome.

The motor-scooter-handlebar syndrome.


Prostaglandins in amine-peptide-secreting tumours.


Mobilisation of iron in pregnancy.

Mobilisation of iron in pregnancy.


Renal clearance of sodium sulphadimidine in normal and uraemic subjects.


Controlled trial of a diet high in unsaturated fat for prevention of atherosclerotic complications.


Method of assessing prognosis in patients with malignant melanoma.


Prescriptive screening.

Prescriptive screening.


Bacteria in the ward.

Bacteria in the ward.


An extra X chromosome.

An extra X chromosome.


Misuse of anaesthetic eye-drops.

Misuse of anaesthetic eye-drops.


Microscopic lesions in head injury.

Microscopic lesions in head injury.


Clofibrate and muscle.

Clofibrate and muscle.


Dirty dish-cloths.

Dirty dish-cloths.


Tape or type?

Tape or type?


Diabetes and pancreatitis.

Diabetes and pancreatitis.


Family-planning services in Africa and the Middle East.


Objectivity in clinical psychiatric research.


Personal and population medicine.

Personal and population medicine.


Methicillin-resistant staphylococci.

Methicillin-resistant staphylococci.


Symptoms of large-intestine cancer.

Symptoms of large-intestine cancer.


Running towards Olympus.

Running towards Olympus.


Dropped finger.

Dropped finger.


Fucosidosis?

Fucosidosis?


Adrenocortical function in mental illness.


Serum-insulin in remission of juvenile diabetes.


A new polydactyly-imperforate-anus-vertebral-anomalies syndrome?


Intravascular coagulation and hyaline-membrane disease.


Electrocardiographic changes after intrathecal hypertonic saline solution.


Paracetamol and mitosis.

Paracetamol and mitosis.


Haemolytic-uraemic syndrome.

Haemolytic-uraemic syndrome.


IgA and partial deletions of chromosome 18.


Oral contraceptives and cerebral blood-flow.


Inhibition of reagin-induced passive cutaneous anaphylaxis.


Lysergic-acid-diethylamide and cannabis as possible teratogens in man.


Automobile exhaust standards.

Automobile exhaust standards.


Culture, symbol and value in the social etiology of behavioral deviance.


Structure of ribosomes of chromatoid bodies: three-dimensional Fourier synthesis at low resolution. A three-dimensional Fourier synthesis at an axial resolution of 75 angstroms of optical diffraction data from electron micrographs of stained sections of chromatoid bodies reveals the position of the large and small ribosomal subunits within these crystals of ribosomes.


Genetic implications of common region sequence comparisons of lambda immunoglobulin chains differing at position 190. The common regions of two lambda chains (amino acid residues 109 to 213) have been partially sequenced. These two human immunoglobulin chains have lysine at position 190, but are otherwise identical in their common-region sequence to four reported lambda chains that have arginine at position 190. The single amino acid interchange at position 190 may be explained either by an ambiguous codon at this position or by a gene duplication so recent that only a single mutational event has occured.


Monosymptomatic gamma globulin elevation in CSF as an indicator of multiple sclerosis.


Effect of changes in trophic hormone secretion on the 3H-uracil uptake by adenohypophyseal cells.


Neutrophil alkaline phosphatase activity. Effect of certain oral contraceptive hormones.


Monoclonal gammopathy in a child with leukemia.


Immunochemical quantitation of proteins in single cells. I. Carbon anhydrase B, beta-chain hemoglobin and gamma-chain hemoglobin in some normal and abnormal erythrocytes.


Diarrhea at the Olympics.

Diarrhea at the Olympics.


Organ transplants--a new type of nursing?


Benign hyperplasia of the prostate.

Benign hyperplasia of the prostate.


Anesthetist's view of the traumatized patient.


Nursing care of patient following prostatectomy.


Further observations of psychological factors involved in CNV genesis.


A comparative study on pulsatile intracerebral impedance and rheoencephalography.


The auditory evoked response in normal and autistic children during sleep.


A high frequency mechanism which underlies visual evoked potentials.


The muscle silent period and spindle function in man.


An analysis of rapid eye movements of sleep in the monkey.


Evoked somatic activity in nucleus medialis dorsalis: a micro-electrode study.


Maturation of epileptiform activity.

Maturation of epileptiform activity.


An evoked potential study of limbic projections to nuclei of the cat septum.


Facilitation of secondary visual evoked responses by stimulation of limbic structures.


A small photic stimulator with fiber optic light guides.


A rapid and simple method for the fabrication of arrays of recording electrodes.


A gold plated, platinum tipped, stainless steel micro-electrode.


A subclass of human gamma-A-globulins (gamma-A2) which lacks the disulfied bonds linking heavy and light chains. The gammaA2-subgroup of gammaA-globulins, previously delineated by antigenic studies, was found to differ strikingly from other immunoglobulins in the manner in which the polypeptide chains are bound together. The heavy and light chains were not linked to each other by disulfide bonds. Instead the light chains were disulfide linked to one another, and were present in the gammaA2-molecule as disulfide bridged L-L dimers. Antisera specific for gammaA2-proteins indicated the occurrence of two different antigenic types in all normal sera as well as saliva and colostrum. Both of these showed the unique interchain disulfide linkage. Quantitative analyses indicated higher levels of gammaA2-proteins in external secretions.


Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. I. Characterization of the phenomenon. In the presence of specific antigen, lymph node cells from inbred rats with delayed hypersensitivity to tuberculoprotein, bovine gammaglobulin, and egg albumin produced progressive destruction of monolayers of rat embryo fibroblasts in tissue culture, first apparent at 48 hr and maximal at 72 hr. The effect was specific and did not depend on a genetic difference between the lymph node cells and target cells. It required antigen concentrations equal to or greater than 1.25 microg/ml and lymphocyte: target cell ratios of approximately 10 or 20:1. It could be evaluated both by a plaquing technique and by cell enumeration with an electronic particle counter.


An analysis of the toxic actions of purified streptolysin O on the isolated heart and separate cardiac tissues of the guinea pig. The response of isolated guinea pig hearts to perfusion with purified streptolysin O is characterized by a rapid, but transient, decrease in rate and amplitude of contraction; these reactions are superimposed upon a gradual, irreversible, loss of ventricular contractility. At ventricular standstill, the atria continue to beat spontaneously in a normal way. Isolated ventricle strips prepared from such preparations can be driven electrically, and their behavior is functionally indistinguishable from that of similar preparations made from normal hearts. Tests on spontaneously beating isolated atrial pairs show that the toxin induces a dose-dependent, reversible, decline in rate and amplitude which is accompanied by a marked, but transient, increase in the velocity of repolarization of the intracellular potential. The atrial reactions were completely blocked by atropine and potentiated by eserine. Acetylcholine was detected in the perfusates obtained by incubating a large pool of atrial tissue with active toxin, supporting the inference that the transient mechanical and electrophysiological reactions to toxin might be consequences of the release of acetylcholine from these tissues by the active toxin. Control studies showed that only the active toxin had the capacity to induce the cardiac responses. The toxin was active only in the reduced but not the oxidized form. The effects of the active toxin were modified if it were heated prior to challenge, and they could be neutralized by specific antiserum and inhibited by cholesterol. Since the driven ventricle strip was mechanically and electrophysiologically insensitive to streptolysin O, the irreversible changes in the whole heart must have occurred because of a defect in the atrioventricular conduction system.


The mechanism of the action of caffeine on sarcoplasmic reticulum. Evidence is presented that caffeine does not act on the mitochondrial Ca uptake system and that its effect cannot be attributed to the accumulation of adenosine 3',5'-phosphate. Two distinct caffeine effects are described. At high ATP concentrations caffeine decreases the coupling between ATP hydrolysis and Ca inflow. It either inhibits inflow without any inhibition of the rate of ATP hydrolysis, or it stimulates the ATPase activity without stimulating Ca inflow. These high ATP concentrations (much higher than needed for the saturation of the transport ATPase) greatly reduce the control of the turnover rate of the transport system, by accumulated Ca. At low ATP concentrations when the transport system is under maximal control by accumulated Ca, caffeine inhibits the ATPase activity without affecting the rate of Ca inflow.


Histochemical staining and microchemical studies of fructose 1,6-diphosphate splitting enzymes in the pancreatic islets and liver of NZO mice.


Histochemical observations on amyloid with reference to polarization microscopy.


Cytomegalovirus infection following extracorporeal circulation in children. A prospective study.


Chromosomal alteration and development of tumors. XIX. Chromosome constitution of tumor cells in 16 plasma cell neoplasms of BALB-c mice.


Effect of feeding on gastric and oesophageal pressures in the newborn.


Magnesium-deficiency syndrome in burns.

Magnesium-deficiency syndrome in burns.


Blood-levels of thyrotrophic hormone, protein-bound iodine, and cortisol in schizophrenia and affective states.


A correlation between urinary steroid metabolites and pathways of steroidogenesis in human breast-tumour tissue.


Effect of potassium on blood-sugar and plasma-insulin levels in patients undergoing peritoneal dialysis and haemodialysis.


Hair-root changes in Andean Indian children during marasmic kwashiorkor.


An attempt to vaccinate owl monkeys (Aotus trivirgatus) against falciparum malaria.


Lignin: a bile-salt sequestrating agent.


Autoallergy in pemphigus.

Autoallergy in pemphigus.


Even more concentrated antihaemophilic globulin.


Subacute problems.

Subacute problems.


Anastomotic ulcer.

Anastomotic ulcer.


Glucose versus fructose.

Glucose versus fructose.


Alcoholism in industry and family.

Alcoholism in industry and family.


Those that would not.

Those that would not.


A social psychiatrist's view of medical care.


Mental health of students receiving clinical psychiatric training.


Green light on administration?

Green light on administration?


The origins of violence.

The origins of violence.


Sucrose intake and coronary heart-disease.


Carcinoma of the colon and rectum.

Carcinoma of the colon and rectum.


Insulin response to glucagon in obese children.


Emotional problems in a chronic haemodialysis unit.


Coli serotypes in the urinary tract.

Coli serotypes in the urinary tract.


Anaphylacti shock after intravenous galactose.


Dropped finger.

Dropped finger.


Remission of juvenile diabetes.

Remission of juvenile diabetes.


Hypercalcaemia from calcium resin.

Hypercalcaemia from calcium resin.


Pooled or personalized secretaries?

Pooled or personalized secretaries?


Vasectomy for voluntary male sterilization.


Defence mechanisms of the bladder.

Defence mechanisms of the bladder.


Smoking and pregnancy.

Smoking and pregnancy.


Complications of depressed skull fracture.


Oral contraceptives and caeruloplasmin activity.


Serum-albumin and insulin antagonism.

Serum-albumin and insulin antagonism.


Safety of domiciliary midwifery.

Safety of domiciliary midwifery.


Scanning electron microscopy of articular surfaces.


Effects of pregnanolone and progesterone.


Immunological aspects of organ and tissue transplantation.


"Dilantin" overdosage.

"Dilantin" overdosage.


Induction of leukemia and ovarian tumors in mice by pulse-doses of polycyclic aromatic hydrocarbons.


Binding of chlorpromazine and thioproperazine in vitro. 3. Fluorometric measurement of changes in Limulus polyphemus (horseshoe crab) myosin B structure and enzyme activity afrer treatment with phenothiazine drugs.


Amino acid sequence at the C-terminus of guinea pig kappa chains obtained from anti-DNP antibodies.


Renal failure and interstitial nephritis due to penicillin and methicillin.


Operating theatre staffing.

Operating theatre staffing.


Histochemical demonstration of histamine in paraffin sections by a fluorescence method.


Relative effictiveness of 75Se and 125-I as lebels for rabbit anticanine urokinase.


Mengovirus replication in Novikoff rat hepatoma and mouse L cells: effects on synthesis of host-cell macromolecules and virus-specific synthesis of ribonucleic acid. Novikoff cells (strain N1S1-67) and L-67 cells, a nutritional mutant of the common strain of mouse L cells which grows in the same medium as N1S1-67 cells, were infected with mengovirus under identical experimental conditions. The synthesis of host-cell ribonucleic acid (RNA) by either type of cell was not affected quantitatively or qualitatively until about 2 hr after infection, when viral RNA synthesis rapidly displaced the synthesis of cellular RNA. The rate of synthesis of protein by both types of cells continued at the same rate as in uninfected cells until about 3 hr after infection, and a disintegration of polyribosomes occurred only towards the end of the replicative cycle, between 5 and 6 hr. The time courses and extent of synthesis of single-stranded and double-stranded viral RNA and of the production of virus were very similar in both types of cells, in spite of the fact that the normal rate of RNA synthesis and the growth rate of uninfected N1S1-67 cells are about three times greater than those of L-67 cells. In both cells, the commencement of viral RNA synthesis coincided with the induction of viral RNA polymerase, as measured in cell-free extracts. Viral RNA polymerase activity disappeared from infected L-67 cells during the period of production of mature virus, but there was a secondary increase in activity in both types of cells coincidental with virus-induced disintegration of the host cells. Infected L-67 cells, however, disintegrated and released progeny virus much more slowly than N1S1-67 cells. The two strains of cells also differed in that replication of the same strain of mengovirus was markedly inhibited by treating N1S1-67 cells with actinomycin D prior to infection; the same treatment did not affect replication in L-67 cells.


Effect of starvation on the function and morphology of rat pancreas.


Histophysical and histochemical investigations of myoclonus bodies.


The nature of the metabolic defect in Refsum's disease.


Studies on the biochemical defect in heredopathia atactica polyneuritiformis (Refsum's disease).


Phytanic acid levels in serum and central nervous system in Refsum's disease.


Residues in food and feed. Pesticide residue levels in foods in the United States from July 1, 1963, to June 30, 1967.


Residues in food and feed. Rate of decline of chlorinated hydrocarbon pesticides in dairy milk.


Residues in fish, wildlife, and estuaries. Insecticide residues in grouse and pheasant of South Dakota.


Clinical value of intestinal biopsy.

Clinical value of intestinal biopsy.


Symbol accentuation: the perceptual transfer of meaning from spoken to printed words.


A comparison of four stimulus-response channels in paired-associate learning.


Contact and delayed hypersensitivity in the mouse. I. Active sensitization and passive transfer.


Heterogeneity of the antibody response of rabbits immunized with acrylic particle-bovine serum albumin complexes.


Immunofluorescence sudies on Addison's disease.


Anaphylactic resensitisation in relation to circulating antibody levels in the guinea pig.


The form and function of the sieve tube: a problem in reconciliation.


Fixation of C' and C'la by rabbit gamma-G- and gamma-M-antibodies with particulate and soluble antigens.


Stability of human leukocyte granules which contain histamine.


Preparation of fluorescent antibody reagents monospecific to heavy chains of human immunoglobulin.


Presence of two different immunoglobulin heavy chains in individual cells of established human hematopoietic cell lines.


Studies of the chicken immune response. I. Correlation of the cellular and humoral immune response.


The induction of acute glomerulonephritis in rabbits with soluble antigens isolated from normal homologous and autologous urine.


Amphibian plasma cells.

Amphibian plasma cells.


Treatment of migraine with propranolol.

Treatment of migraine with propranolol.


Thyroid binding proteins.

Thyroid binding proteins.


In a nutshell: immunoglobulins.

In a nutshell: immunoglobulins.


Mechanism of action and structure of acid deoxyribonuclease.


Human heart transplantation. The diagnosis of rejection.


Evaluation and application of the fluorochrome stain for microscopic detection of mycobacteria in clinical specimens.


Clinico-pathological study of thymic dysplasia.


A methof for demonstration of the distribution of sebum on the skin surface.


Selective gamma-A-globulin deficiency, with dominant autosomal inheritance in a Swiss family.


Heredopathia atactica polyneuritiformis (Refsum's diseases). An audiological examination of two patients.


Gamma globulin synthesis in pregnant rabbits.


A structural study of human exocrine IgA globulin.


Production and properties of mouse antihapten antibodies.


Effects of chronic bronchopulmonary disease and aging on human nasal secretion IgA concentrations.


Hepatitis from methimazole during adrenal steroid therapy for malignant exophthalmos.


Immunoglobulin production in bronchial mucosa and bronchial lymph nodes, particularly in cystic fibrosis of the pancreas.


Fluorescent plague assay of rubella virus infectivity.


The detection and characterization of phagocytic cells in established human cell lines synthesizing immunoglobulins.


Teaching aids and the practitioner.

Teaching aids and the practitioner.


Studies of the development of congenital anomalies in embryos of riboflavin-deficient, galactoflavin fed rats. I. Growth and embryologic pathology.


Identification and evaluation of amitryptiline and its basic metabolites in rabbit's urine.


The binding of sodium dodecyl sulphate to various proteins. 1. The binding of sodium dodecyl sulphate to proteins by equilibrium dialysis was investigated. 2. Most of the proteins studied bound 90-100% of their weight of sodium dodecyl sulphate. 3. The glycoproteins studied bound 70-100% of their weight of sodium dodecyl sulphate, calculated in terms of the polypeptide moiety of the molecule. 4. Proteins not containing S.S groups bound about 140% of their weight of sodium dodecyl sulphate. 5. Reduction of four proteins containing S.S groups caused a rise in sodium dodecyl sulphate binding to 140% of the weight of protein. 6. The apparent micellar molecular weights of the protein-sodium dodecyl sulphate complexes were measured by the dye-solubilization method; they were all found to have approximately the same micellar molecular weight (34000-41000) irrespective of the molecular weight of the protein to which they were attached.


Immunoelectrophoretic analysis of labeling of serum proteins after administration of the carcinogen N-hydroxy-N-2-fluorenylacetamide.


Effects of oral contraceptives and pregnancy on thyroid function.


Radioimmunoelectrophoretic analysis of thyroxine-binding proteins in normal human sera.


Immunoglobulin determination. Evaluation of the results of immunoelectrophoretic analysis and the radial diffusion method.


Studies on the M-components of human serum. Immuno-gel filtration on a plate as a second step in thin-layer gel filtration.


Structural studies of an unusual myeloma protein.


2-hydroxy-3-naphthoic acid anilide phosphate as a fluorescent histochemical substrate for phosphatase.


Adamantylamines by direct amination of 1-bromoadamantane.


Histochemical changes of phosphatases in the prostatic gland.


The mechanism of anaphylactic histamine release from rabbit leucocytes.


The histamine content of rabbit leucocytes and its release during in vitro anaphylaxis.


Ultrastructural changes of large rabbit blood vessels following mild mechanical trauma.


Serum immunoglobulin levels in sickle cell disease and thalassemia major.


False-positive reactions for syphilis. Serological abnormalities in relatives of chronic reactors.


Systemic lupus erythematosus.

Systemic lupus erythematosus.


Use of circumferential tangential cryostat sections of the intestine in the diagnosis of Hirschsprung's disease. Technical and staining methods are described for making tangential sections using a specially prepared chuck surface in a cryostat. The method gives a rapid definitive diagnosis of Hirschsprung's disease in children.


Glove box system for micro-determination of protein-bound iodine in children's blood.


Gel scintillation counting of I-131 in plasma at high efficiencies. A method is described for assaying low concentrations of (131)I in plasma by detecting the beta radiation in a gel scintillator. Higher detection efficiencies are obtained compared with measurements of the gamma radiation from this radioisotope using a well-type crystal of sodium iodide.


Demonstration of Paneth cell granules using Naphthalene Black.


Screening test for an automated protein-bound iodine technique.


Antibodies in hydatid disease.

Antibodies in hydatid disease.


Evaluation of discordant laboratory data in patients with thyroid disorders. The usefulness of the various tests of thyroid function has been evaluated over a three-year period. It is concluded that an uptake test and estimation of the serum protein-bound radioactive iodine (PB (131)I), supplemented as required by the protein-bound iodine (PBI), remain the best routine tests of thyroid function. Forty-five patients who gave discordant results on these tests over this period have been studied in detail and the value of other tests of thyroid function has been explored.


Serum glycoproteins in experimentally induced malaria in man.


Sulfation factor: studies of its removal from plasma and metabolic fate in cartilage.


Studies on the mode of action of oral contraceptives: effect of chlormadinone on pituitary FSH and LH contents of the female rat.


Relationship between competence for transfection and for transformation. Deoxyribonucleic acid (DNA) extracted from phage SPP1 is highly infectious on Bacillus subtilis competent cells; the efficiency of infection is 5 x 10(3) to 6 x 10(3) phage equivalents per plaque-forming unit. This DNA was used to study the relationship between competence for transfection and for transformation. The experiments were concerned with the frequency of infection and transformation in mutants exhibiting different levels of competence, the effect of periodate on competence for infection and for transformation, the competition between phage and bacterial DNA, the transformation of cells preinfected with phage DNA, and the infection of cells pretreated with bacterial DNA. The data show that B. subtilis cells competent for transformation are also competent for transfection and vice versa; transfection with phage DNA represents, therefore, a simple way to measure the total number of competent cells in a culture. The fraction of competent cells, determined by SPP1 DNA infection, varied from 10(-2) to 7 x 10(-2).


Supervoltage irradiation. Prophylactic vs therapeutic use for transitional cell carcinoma of the bladder, group I.


The effect of corticotropin on the neuromuscular junction. Morphologic studies in rabbits.


Human immunoglobulin A.

Human immunoglobulin A.


Congenital aplasia of the thymus gland (DiGeorge's syndrome).


When and how to use higher 131-I doses for hyperthyroidism.


Studies on the structure, ultrastructure and function of the subcommissural organ-Reissner's fibre complex of the European eel Anguilla anguilla L.


Monoamine-containing fibres in the pituitary neuro-intermediate lobe of the pig and rat.


Histochemical studies on the lipo-pigments in the nerve cells. A comparison with lipofuscin and ceroid pigment.


On the nature of hyaline microthrombi. A light microscopical, immunofluorescent and ultrastructural study.


Further investigation of specific and non-specific adsorption of serum globulins to Staphylococcus aureus.


An assessment of serum protein electrophoresis in sarcoidosis.


Phosphotungstic acid staining of the organ of Corti for electron microscopy.


Patient education.

Patient education.


The use of oxone to facilitate specific tissue stainability following osmium fixation.


Computer-aided language development in nonspeaking children.


Significance of Rh-sensitization during pregnancy: its relation to a preventive programme. A study of the incidence of Rh-sensitization showed a 6.5% incidence of anti-D appearing for the first time during the last trimester of pregnancy. In 24 of the 29 subjects these antibodies were weak, and were found only when a sensitive technique using enzyme-treated Rh-deletion test cells was employed. The remaining five, however, had high-titre antibodies, which were associated with a positive Coombs test on cord blood.Rh-immune globulin administered at delivery resulted in disappearance of the anti-D in all but one of the subjects with weak antibody to whom it was given, suggesting that this treatment can reverse early sensitization. There was no effect when Rh-immune globulin was given to one subject with a high anti-D titre.Since sensitization has been found to occur frequently during the last trimester of pregnancy, an antenatal schedule of prophylaxis is advocated.


Diabetes mellitus in patients with benign prostatic hyperplasia. Of 51 patients submitted to operation for benign prostatic hyperplasia three (5.9%) were knwon, diabetics and two others had undergone surgery for peptic ulcer. Of the remaining patients half (23 out of 46) were found to be diabetic; 40% (20 patients) had a history of previous cardiac infarction or electrocardiograph evidence of myocardial ischaemia.It is suggested that these findings add further support to the hypothesis that benign prostatic hyperplasia is one manifestation of a relative increase of oestrogen secretion with advancing age.


Muscular subaortic stenosis. Prevention of outflow obstruction with propranolol.


Visual evoked potentials in binocular rivalry.


New possibilities in the detection of evoked responses offered by high speed relays and field effect transistors.


Psychopathological correlations of the non-specific portion of visual and auditory evoked potentials and the associated contingent negative variation.


Lemniscal afferents and extracallosal mechanisms for interhemispheric transmission of somato-sensory evoked potentials.


Comparison of the potentials recorded from the occipital, temporal and central regions of the human scalp, evoked by visual, auditory and somato-sensory stimuli.


Mathematical methods and electronic computers in the study of physiological electrical signals.


Varieties of computer analysis of electrophysiological potentials.


The visual evoked potential: physiological, developmental and clinical aspects.


Variations in average visual evoked potential as a function of the alpha rhythm phase ("autostimulation").


Evaluation of photically evoked responses in man by graphic superimposition, automatic averaging and selected frequencies.


Visual evoked responses during sleep in man.


The effects of attention and distraction on the visual evoked potential in man: a preliminary report.


Recovery cycle of visual evoked potentials in normal and schizophrenic subjects.


Spatial visual evoked potentials as physiologic language elements for color and field structure.


Some observations on the variability of evoked potentials.


To Professor Mario Gozzano.

To Professor Mario Gozzano.


Argyrophile and argentaffin reactions in individual granules of enterochromaffin cells of the dog.


Adrenal function in tropical sprue.

Adrenal function in tropical sprue.


Endodontic treatment and conservation of temporary teeth.


Observations on the mechanism of adaptation to low protein intakes.


Incidence, significance, and management of early bradyarrhythmia complicating acute myocardial infarction.


Alpha-methyl-p-tyrosine in the management of phaeochromocytoma.


Comparison between inulin and 51Cr-labelled edetic acid for the measurement of glomerular filtration-rate.


Intravenous glucose-tolerance, insulin, and free-fatty-acid levels in burned patients.


Clinical and biochemical studies of a patient with a corticosterone-secreting adrenocortical tumour.


Death and division of lymphocytes. Neglected factors in assessment of P.H.A.-induced transformation.


A possible drop in first-week-mortality rate for low-birth-weight infants after phenobarbitone treatment.


Pyelonephritis without bacteria.

Pyelonephritis without bacteria.


Examining the general practitioner.

Examining the general practitioner.


Chalones and cancer.

Chalones and cancer.


Acute post-partum renal failure: a new syndrome?


Hospital building: a case-report.

Hospital building: a case-report.


Electroencephalography in Britain.

Electroencephalography in Britain.


Nurses in the practice.

Nurses in the practice.


Alpha-methyl-tyrosine and phaeochromocytoma.


Outpatience.

Outpatience.


Consumers and the Green-paper. Participation in the health services.


What happens when geriatric patients leave hospital?


Hypercalcaemia from calcium resin.

Hypercalcaemia from calcium resin.


Vasectomy for voluntary male sterilisation.


Delayed meconium passage and hyperbilirubinaemia.


Advice on abortion.

Advice on abortion.


Vaccination against mumps.

Vaccination against mumps.


Chloroquine-resistant falciparum malaria.


Treatment of migraine with propranolol.

Treatment of migraine with propranolol.


Cerebrospinal-fluid pH and metabolic coma.


Emotional problems in a chronic haemodialysis unit.


Unsaturated fats and coronary heart-disease.


Sewage disposal.

Sewage disposal.


Gastric iron binding in haemochromatosis.


Significance of post-gamma-proteinuria.

Significance of post-gamma-proteinuria.


Platelet-function tests and clofibrate.

Platelet-function tests and clofibrate.


Environmental temperature and death-rate of women from breast neoplasms.


XYY with abnormal genitalia.

XYY with abnormal genitalia.


Mites and house-dust allergy.

Mites and house-dust allergy.


Treatment of oat-cell carcinoma of lung.


Foetal acid-base during caesarean section.


Monowar Khan Afridi.

Monowar Khan Afridi.


Helen Elizabeth Rodway.

Helen Elizabeth Rodway.


Coronary-artery thrombosis and the acute attack of coronary heart-disease.


Vesicoureteric reflux in patients with bacteriuria in pregnancy.


Lymphocyte trnsformation induced by encephalitogenic factor in multiple sclerosis and other neurological diseases.


Lymphocyte transformation in multiple sclerosis. Inhibition of unstimulated thymidine uptake by a serum factor.


Plasma-levels of lignocaine after intramuscular injection.


Implantation of a foetal thymus, restoring immunological competence in a patient with thymic aplasia (Digeorge's syndrome).


Foetal thymic transplant in a case of Digeorge's syndrome.


Continuous controlled humidification of inspired air.


Extracorporeal liver perfusion using a new perfusion chamber.


Beta-adrenergic blockade in thyrotoxic myopathy.


How much for education?

How much for education?


Inhibition of antiplasmin, and effect of protease I in patients with leukaemia.


Transplanting the thymus.

Transplanting the thymus.


The zoonoses.

The zoonoses.


Bacterial checks on food.

Bacterial checks on food.


Off work.

Off work.


Unnecessary crowds.

Unnecessary crowds.


Breast cancer and atomic bombing.

Breast cancer and atomic bombing.


"Switch": a system producing a full hospital case-history on computer.


The Royal Commission and London.

The Royal Commission and London.


Haemodialysis in the treatment of liver failure.


Cost of treatment of addiction.

Cost of treatment of addiction.


Electroencephalography in Britain.

Electroencephalography in Britain.


Chalones and cancer.

Chalones and cancer.


Measles and subacute sclerosing panencephalitis.


Effect of phenobarbitone on low-birth-weight infants.


Mallet finger.

Mallet finger.


Excess Barr bodies in patients in mental hospitals.


Prophylactic lithium?

Prophylactic lithium?


Growth hormone in protein-losing enteropathy.


Recovery after massive overdose of diphenhydramine and methaqualone.


Measurement of glomerular filtration-rate.


Neonatal conjunctivitis.

Neonatal conjunctivitis.


Birth control and human evolution.

Birth control and human evolution.


Methotrexate and smallpox vaccination.

Methotrexate and smallpox vaccination.


Absence of fingerprints in four generations.


Digital dermatoglyphics and blood-groups.


Leg exerciser for non-ambulant patients.


Methotrexate in psoriasis.

Methotrexate in psoriasis.


Peter Ferrers Lucas; M.D. Cantab., F.R.C.P.


Whipple's disease. Early diagnosis.

Whipple's disease. Early diagnosis.


Human aggression in psychiatric perspective.


Bloom's syndrome.

Bloom's syndrome.


Physical and chemical studies on glycoproteins. 3. The microheterogeneity of fetuin, a fetal calf serum glycoprotein.


Analysis of the proteins in human seminal plasma.


Kinetics of 3-methyloproline inhibition of actinomycin biosynthesis.


Muscle cramps in chronic thyrotoxic myopathy. Report of a case.


Comments on the psychoanalytic psychology of adaptation, with special reference to the role of affects and the representational world.


Variable regions of heavy and light polypeptide chains of the same gammaG-immunoglobulin molecule.


Audio, visual, and audio-visual instruction with mental practice in developing the forehand tennis drive.


Electron microscopic and histochemical studies on human cellular cementum.


The IgD in the cerebrospinal fluid.

The IgD in the cerebrospinal fluid.


The ischemic zone surrounding acute myocardial infarction. Its morphology as detected by dehydrogenase staining.


Measles and readiness for reading and learning. II. New Haven study.


Measles and readiness for reading and learning. 3. Wappingers Central School District study.


Man-made environmental hazards. I. How man shapes his environment.


Immune serum globulin for prevention of viral hepatitis. Recommendation on immunizing practices.


Man-made environmental hazards. II. What man can do technologically to restore his environment.


The interaction of gamma-globulin with lipids.


Serum hyperviscosity in multiple myeloma and its clinical and neuro-psychiatric implications.


Determination of different motor nerve fibre characteristics with the use of "stimulus strength-latency" relation.


Different effects of methylmercaptoimidazole and propylthiouracil on thyroidal 131-I release in rats on ClO4.


Late cerebral radionecrosis.

Late cerebral radionecrosis.


Differences in the immune response of rabbits to p-aminobenzoic acid and sulphanilic acid, conjugated with BGG.


Studies on antibody formation of thymus cells, lymph node cells and spleen cells. 3. Alterations in the number of antibody producing cells and serum antibody titers following secondary immunization.


Somatic complaints in psychiatric disorders: social and cultural factors.


A modified method for lead staining of thin sections.


On the contrast by negative staining methods in electron microscopy.


The structure and infective process of a contractile Pseudomonas aeruginosa bacteriophage.


Double staining of tobacco-mosaic-virus-infected material using phosphotungstic acid and uranyl acetate during dehydration.


Growth of mumps virus in organ cultures of rhesus testis.


The effect of secondary infection on the pattern of pyuria in experimental murine pyelonephritis.


The mechanism of formation of asbestos bodies.


The differentiation of the acidophil cell in the human foetal adenohypophysis.


The properties and development of conchoidal bodies in sarcoid and sarcoid-like granulomas.


In vitro production of immune globulins by lymphoid tissue in allograft rejection.


Immunologlobulin lambda chain structure: two genes, one polypeptide chain.


Migratory polyarthritis occurring with methimazole therapy.


Defining the problem of air pollution in metropolitan Birmingham, Alabama.


Flagellar adenosine triphosphatase from sea urchin sperm: properties and relation to motility. Adenosine triphosphatase activated by divalent cations is apparently a component of the motile apparatus in flagella of Arbacia sperm, as judged by the activity of this enzyme in intact flagella, glycerol-extracted flagella, and soluble extracts prepared from flagella. However, the variation in the physical properties and in the amount of enzyme obtained after a variety of treatments suggests that additional components are involved in the motile mechanism. These features distinguish the soluble flagellar enzyme from adenosine triphosphatases of other motile cells.


Thermogenesis of the stable L-forms of Proteus mirabilis and their parent bacteria.


Induction of lactic acid oxidation in Mycobacterium 279.


The antibiotic edeine. 8. The mode of action of edeine A and B.


Oxygen uptake by a thermophilic strain of Bacillus subtilis in different culture conditions.


The use of the technique of van Schreven for the taxonomy of Rhizobium strains.


The deoxyribonucleic acids of some BCG substrains.


Staining technique for the genus Thiobacillus.


The influence of the anti-brucella agglutinin avidity on the results of the milk-ring-test (ABR).


Effect of combinations of some sulfur-containing amino acids on efficiency of Rhizobium meliloti strains.


Lung auto-antibodies in the blood of children with bronchial asthma.


Methods for the preparation of standardized immunofluorescent reagents of increased specificities.


Hemoclar in ophthalmology.

Hemoclar in ophthalmology.


A microelectrophoresis method for heparin.


Hemopexin in newborn infants of diabetic mothers.


Impairment of plasma glycoprotein synthesis in choline deficiency compared with effects of carbon tetrachloride intoxication.


Effect of norepinephrine and uncoupling agents on brown tissue.


Generalized cytomegalic inclusion disease, hypergammaglobulinemia and antithrombin activity in a newborn infant.


A study of troponin, a myofibrillar protein from rabbit skeletal muscle.


Developments in immunofluorescence: the need for standardization. DIFFICULTIES EXPERIENCED BY THE NEWCOMER TO THE FLUORESCENT ANTIBODY STAINING METHOD LARGELY ARISE FROM TWO CAUSES: (1) the many modifications in the procedure which have been suggested over the last decade; (2) the variability of the basic reagent, fluorescent conjugate, in terms of potency and specificity. The ensuing problem of non-reproducibility is clearly an important factor for clinical laboratories now faced with increasing demands for routine tests involving immunofluorescence. In this paper a simple approach to standardization is described which, if adopted, would lead to a more efficient use of the method.


Automobile engines: pollution and power.


Human monocytes: distinct receptor sites for the third component of complement and for immunoglobulin G. Human monocytes contain two distinct receptor sites, one specific for the third component of complement (C'3), the other for immunoglobulin G(gammaG). The two receptors may function either independently or cooperatively in the induction of phagocytosis. Ingestion of erythrocytes coated with immunoglobulin M antibody requires a relatively large number of bound C'3 molecules per cell. Ingestion of erythrocytes sensitized with gammaG antibody is independent of complement; however, the reaction is inhibited by concentrations of gammaG far below those in normal serum. Inhibition by gammaG-globulin is overcome by a relatively small number of bound C'3 molecules per cell. The two monocyte receptors exert a cooperative effect on ingestion by monocytes of erythrocytes coated with gammaG antibody in the presence of inhibitory amounts of free gammaG.


Neurons: secretory activity during limb regeneration and induction in the newt. Material staining with aldehyde fuchsin appeared in sensory ganglion cells supplying a regenerating limb or nerve-induced blastema and in regenerating nerve fibers within the blastema. With the electron microscope, large (1000 to 2500 angstroms), dense granules were observed in the perikarya and within end bulbs of peripheral nerves. Secretory materials may be elaborated and transported by neurons during limb regeneration and induction in the newt.


The neuropathology of ducky, a neurological mutation of the mouse. A pathological and preliminary histochemical study.


The human body burden of lead.

The human body burden of lead.


Peripheral neuropathy in globoid cel leucodystrophy (morbus Krabbe).


An investigation into the nature of the intracellular inclusions formed by mumps virus, as determined by the combined use of immunofluorescence and methylgreen-pyronin stain.


Adenovirus transformation of hamster embryo cells. I. Assay conditions.


Studies on several strains of pseudorabies (Aujeszky) virus showing different virulence by means of the immuno- and acridine orange fluorescence.


Ocular pemphigus. An electron microscopic study of the conjunctival and corneal epithelium.


Selective atrophy of the radial peripapillary capillaries in chronic glaucoma.


Abnormalities of serum immunoglobulins (IgA, IgM, IgG) and recurring infections of the respiratory tract.


Alpha-chain disease: a new immunoglobulin abnormality. A new type of pathological immunoglobulin was found in the serum, urine, and saliva of a young Arab patient with abdominal lymphoma and diffuse lymphoplasmacytic infiltration of the small intestine. This protein is devoid of light chains and is closely related to the alpha polypeptide chains of the gamma(A1) (Le) subclass of immunoglobulin A. It is characterized by electrophoretic heterogeneity, tendency toward polymerization, and a high carbohydrate content. No intracellular synthesis of light chain was detected.


A new inherited serum beta-lipoprotein antigen in man and its relation to the Ag(xy) system.


Observations on the embryonic development of the cyclophyllidean cestode. Diplophallus polymorphus with emphasis on the histochemistry of the egg membranes.


Demonstration of an intercellular substance in mouse cerebral cortex.


Argyrophile and argentaffin reactions in individual granules of enterochromaffin cells of reserpine treated guinea pigs.


Endocrine cells in the antro-pyloric mucosa of the stomach.


Lipid and clinical response to a new thyroid hormone combination.


Changes in the distribution of hepatic copper in relation to the progression of Wilson's disease (hepatolenticular degeneration).


Demonstration of phagocytic and trephocytic activities of chicken thrombocytes by microscopy and vital staining techniques.


The effect of antibacterials on Salmonella typhimurium within hatching eggs.


The effect of colchicine on myogenesis in vivo in Rana pipiens and Rhodnius prolixus (Hemiptera). The effect of colchicine on myogenesis in vivo has been studied in the regenerating tadpole tail of the frog, Rana pipiens, and in the abdominal molting muscles of a blood-sucking bug, Rhodnius prolixus Stål. Colchicine is shown to disrupt microtubules in the differentiating muscle cells of both these organisms. The disruption of microtubules is correlated with a loss of longitudinal anisometry in the myoblasts and myotubes of the regeneration blastema in the tadpole tail. Before colchicine treatment, the myotubes contain longitudinally oriented myofibrils. After colchicine treatment, rounded, multinucleate myosacs containing randomly oriented myofibrils are present. It is suggested that the primary function of microtubules in myogenesis in the Rana pipiens tadpole is the maintenance of cell shape. The abdominal molting muscles of Rhodnius undergo repeated phases of differentiation and dedifferentiation of the sarcoplasm. However, the longitudinal anisometry of the muscle fibers is maintained in all phases by the attachments of the ends of the fibers to the exoskeleton, and microtubule disruption does not alter cell shape. The orientation of the developing myofibrils is also unaltered, indicating that the microtubules do not directly align or support the myofibrils in this system.


Membrane modifications in the apical endocytic complex of ileal epithelial cells. Ileal lining cells of the suckling rat possess an "apical endocytic complex" capable of sequestering intact protein from the intestinal lumen. The complex consists of a network of invaginations of the apical plasma membrane, a number of subjacent small vesicles, and a giant supranuclear vacuole. The first two components initially incorporate material from the intestinal lumen and then transfer it to the giant vacuole where it is stored. Their limiting membrane displays striking structural modifications when viewed in various planes of section. Its lumenal dense leaflet appears discontinuous and consists of an ordered array of minute discrete plaques. A dense particle approximately 70 A in diameter is centered over each plaque. The particles are arranged in a two-dimensional square lattice with center-to-center spacing of approximately 120 A.


Electron microscopic investigations of actomyosin as a function of ionic strength. Natural actomyosin at micro = 0.6 appears in various forms, including the regular arrowhead structures originally reported by Huxley (1), when it has been stained negatively with 1% uranyl acetate. In addition to the arrowheads, thin whiskers, 700-1200 A in length and 20 A in width, attached to the arm of the arrowheads have been demonstrated. The dimensions of the whiskers and arms of the arrowheads are practically the same as those of the light meromyosin (LMM) and the heavy meromyosin (HMM) moieties of the single myosin molecule, respectively. Changes in the electron microscopically distinguishable elements during aggregation of natural actomyosin on reduction of the ionic strength have been observed. At micro = 0.4, partial aggregation of the LMM whiskers begins to result in some parallel alignment of the arrowhead-bearing filaments (acto-HMM). In the range of micro = 0.3-0.1, the LMM whiskers merge into smooth filaments which are arranged alternatingly with arrowhead-bearing filaments. Thus, lateral aggregation of composite actomyosin filaments (acto-HMM + LMM whiskers) results with the LMM moieties as links. This view is supported by the following facts: (a) acto-HMM is devoid of whiskers and does not show lateral aggregation at micro = 0.1; (b) natural actomyosin digested with trypsin at micro = 0.6, which was followed by removal of LMM aggregates at low ionic strength, is essentially the same as acto-HMM at micro = 0.1; and (c) digestion with trypsin of natural actomyosin at micro = 0.2 for varying periods of time leads to a separation of arrowhead-bearing filaments from LMM aggregates.


A biochemical and histochemical study of glutamic oxalacetic transaminase activity of rat hepatic mitochondria fixed in situ and in vitro. Rat liver perfused in situ briefly with a glutaraldehyde-formaldehyde mixture was homogenized in isotonic sucrose. The mitochondria, isolated from a homogenate of the perfused liver by differential centrifugation, assumed a slender and compact appearance similar to those often seen in an intact cell. The glutamic oxalacetic transaminase (GOT) activity of this mitochondrial fraction survived an additional formaldehyde fixation and was studied by biochemical and histochemical methods. The biochemical assay of the enzyme activity revealed that the activity was only slightly less than that of an unfixed mitochondrial fraction. The reaction product due to mitochondrial GOT activity was found to be localized to the cristae, as had been demonstrated in an intact liver cell. GOT activity of the mitochondrial fraction isolated from fresh liver tissue homogenate in 0.25 M sucrose was inactivated readily by either glutaraldehyde or formaldehyde and was no longer demonstrable by biochemical and histochemical methods after fixation.


Myofilaments in smooth muscle of guinea pigs taenia coli.


Studies on the site of action of oral contraceptive steroids. I. Effect of antifertility steroids on plasma LH levels and on the response to luteinizing hormone-releasing factor in rats.


Severe endogenous hypertriglyceridemia during treatment with estrogen and oral contraceptives.


Liver function studies in free ranging howler monkeys with hepatic pigmentation.


Treatment of thyrotoxicosis with ionising radiation.


Liver-copper levels in liver disease: studies using neutron activation analysis.


Deposits of immunoglobulin and fibrin in human allografted kidneys.


Leprous endocrinopathy.

Leprous endocrinopathy.


Arterial calcification after vitamin-D therapy in hyperphosphatemic renal failure.


Comparison of clomiphene and human gonadotrophins in failure of ovulation.


Placental localisation using radioactive carbon monoxide and the gamma camera.


Effects of insulin on intestinal glucose absorption.


"Mouth-to-lung airway" for cardiac resuscitation.


Effects of general anaesthetics on microtubules: a possible mechanism of anaesthesia.


Hospital scientists.

Hospital scientists.


Localisation of the placenta.

Localisation of the placenta.


Sparing the nurse.

Sparing the nurse.


Natural history of aortic stenosis.

Natural history of aortic stenosis.


Volunteers and circulars.

Volunteers and circulars.


Paracervical block in obstetrics.

Paracervical block in obstetrics.


A follow-up scheme for detecting hypothyroidism in thyrotoxic patients treated with radioiodine.


Epidemiology and the green paper: a national epidemiological service?


Ankylosing spondylitis.

Ankylosing spondylitis.


Cervical smears and oral contraception.

Cervical smears and oral contraception.


Acute coronary heart-disease.

Acute coronary heart-disease.


Vesicoureteric reflux in pregnancy.

Vesicoureteric reflux in pregnancy.


Pyelonephritis without bacteria.

Pyelonephritis without bacteria.


Emotional-problems in a chronic haemodialysis unit.


Thyroid and adrenocortical function in psychiatric illness.


Chalones and cancer.

Chalones and cancer.


Oral contraceptive and thrombosis of the coeliac artery.


E.M.G. syndrome and carbohydrate metabolism.


Phenobarbitone and biliary excretion.

Phenobarbitone and biliary excretion.


51Cr-edetic-acid clearance and G.F.R.

51Cr-edetic-acid clearance and G.F.R.


Arginine infusion and growth-hormone secretion.


Propranolol and 131-I for thyrotoxicosis.


Isoprenaline resistance in asthma.

Isoprenaline resistance in asthma.


Alcohol in urine and sweat.

Alcohol in urine and sweat.


Chandra's syndrome.

Chandra's syndrome.


Lymphocyte inclusions in rheumatoid arthritis.


Aortic hypoplasia and renal failure.

Aortic hypoplasia and renal failure.


A normal XYY man.

A normal XYY man.


D/D balanced translocations.

D/D balanced translocations.


Working anatomical models for the overhead projector.


Exploded diagrams produced photographically.


Indexing audiovisual aids on a feature card system.


Improved plastic embedding of wet biological specimens.


Immunologic enhancement of tumor xenografts by pepsin-degraded immunoglobulin. The serums from guinea pigs previously injected with mouse Ehrlich ascites tumor cells were fractionated to obtain gamma(2)-immunoglobulin. This immunoglobulin was degraded with pepsin to obtain an F(ab')(2) fragment. Fresh tumor cells were incubated with immunoglobulin or the fragment and injected into normal guinea pigs. The growth of these cells as tumor xenografts was inhibited by the gamma(2)-immunoglobulin and enhanced by the F(ab')(2) fragment. Similar incubation of tumor cells with normal guinea pig gamma(2)-globulin or its derived F(ab')(2) fragment did not alter subsequent tumor growth.


The clinical application of in vivo parathyroid staining.


Comparative quantitation of immunoglobulins in Nigerians.


Immunoelectrophoretic abnormalities in the anodic field of the IgG precipitation arc during central nervous system disorders.


A view of the comparison of the regulation of enzymes in mammalian and microbial systems.


Specific enzyme responses in starved, glucagon-treated or irradiated rats, and general considerations on the mechanisms of induction in animals.


Hypothalamic neurosecretion and photoinduced testicular growth in the tree sparrow, Spizella arborea.


Lysosome formation and surface changes in stimulated peritoneal cells.


Hepaticojejunostomy. Modified longmire operation for bile duct carcinoma.


Some aspects of the fine structure of the reticulo-endothelial system; the cells which clear colloids from the blood stream.


The effect of the dextro isomer of propranolol on sinus rate and cardiac arrhythmias.


Adult hyaline membrane disese: relationship to oxygen therapy.


A correlation of breast imprints (stained by the method of Papanicolaou) and tissue sections.


Thymoma associated with multiple myeloma.


Determinatiion of molecular weight of glycopeptides by exclusion chromatography.


Analysis of 25 cases of malignant synovioma.


Chronic lymphocytic thyroiditis in a 5-year-old girl.


Fluctuation of thyroid function following a single and repeated administration of antithyroid drugs.


Inhibition of cholesterol biosynthesis by dehydroepiandrosterone in lactating mammary gland.


Histamine release from rat peritoneal mast cells: inhibition by colchicine and potentiation by deuterium oxide.


The cardiovascular and catecholamine response to flurothyl convulsion therapy and a comparison with the response to ECT.


Immunological power of the lymphocyte.

Immunological power of the lymphocyte.


Urinary steroids in the prediction of response to adrenalectomy or hypophysectomy. A second clinical trial.


Ten years' experience of sterioid assays in the management of breast cancer. A review.


Proteinuria in malignant hypertension.

Proteinuria in malignant hypertension.


Serum-enzymes in relation to electrocardiographic changes in accidental hypothermia.


Alterations of fibrinolysis and blood coagulation induced by exercise, and the role of beta-adrenergic-receptor stimulation.


Increased skin capillary resistance after hypophysectomy in long-term diabetics.


Tuberculin conversion in leprous families in Northern Nigeria.


Lymphoid suspension cultures from patients with viral hepatitis.


Congenital rubella: an immunological paradox?


Forward-action forceps.

Forward-action forceps.


Slower  ageing?

Slower  ageing?


Chronic idiopathic neutropenia.

Chronic idiopathic neutropenia.


Fibrinolysis, exercise, and propranolol.


Hospital treatment of acute poisoning.

Hospital treatment of acute poisoning.


Systolic murmurs in the aged.

Systolic murmurs in the aged.


Adhesions.

Adhesions.


Unsuspected digitalis abuse.

Unsuspected digitalis abuse.


Play and the sick child. A comparative study of its role in a teaching hospital in London and one in Ghana.


Some factors affecting the smoking habits of a group of teenagers.


Early detection of cancer.

Early detection of cancer.


Patient geography in general practice. Catchment areas of Aberdeen practices.


Behavioural science for preclinical students.


Anticonvulsant drugs and congenital abnormalities.


Skeletal limb deficiencies.

Skeletal limb deficiencies.


Trial of unsaturated-fat diet.

Trial of unsaturated-fat diet.


Diet and cardiovascular disease.

Diet and cardiovascular disease.


Even more concentrated antihaemophilic globulin.


Adrenocortical function in mental illness.


Clomiphene and gonadotrophin in men.

Clomiphene and gonadotrophin in men.


Cytomegalovirus infection following extracorporeal circulation.


Antileukaemic activity of asparaginase.

Antileukaemic activity of asparaginase.


Emulsifying eusol-liquid-paraffin.

Emulsifying eusol-liquid-paraffin.


Oral contraceptives and cerebral blood-flow.


Blastosis in malabsorption syndrome.

Blastosis in malabsorption syndrome.


Bradyarrhythmia complicating myocardial infarction.


Controlling clioquinol.

Controlling clioquinol.


Sudden death after intramuscular frusemide.


Purpura with hypogammaglobulinaemia.

Purpura with hypogammaglobulinaemia.


Pyridoxine-dependency in homocystinuria.


Localisation of the cystic-fibrosis gene.


Marfan's syndrome a hereditary enzymopenia?


Mallet finger.

Mallet finger.


Autosomal factor-VIII deficiency.

Autosomal factor-VIII deficiency.


The royal commission and London.

The royal commission and London.


Hormonal changes during exercise.

Hormonal changes during exercise.


C-reactive protein a normal immunoglobulin?


Mouse myelomas producing precipitating antibody to nucleic acid bases and-or nitrophenyl derivatives.


Rabbit anti-rat lymphocyte serum: relationship between dosages, circulating lymphocytes, and the primary immune response.


Formation of fibrillar structures from poliovirus by alkaline disruption and other treatments.


Mouse myeloma proteins with antihapten antibody acitivity. The protein produced by plasma cell tumor MOPC-315.


Ecological considerations in scrub typhus. 3. Methods of area control. The best of the known methods for control of the chigger vectors of scrub typhus is the application of dieldrin to the ground and low-lying vegetation as a fog or spray at the rate of 2.5 lb to the acre (28 kg/hectare). This has produced a more than 91% reduction in the numbers of Leptotrombidium (L.) akamushi (Brumpt, 1910) and L. (L.) deliense (Walch, 1922) for at least 2 years. Aldrin applied at the rate of 2.25 lb per acre (2.5 kg/hectare) is also highly effective, but less so than dieldrin. Lindane at the rate of about 5 lb per acre (5.7 kg/hectare) ranks third, but offers protection for only about 2 months. Because of the potential hazards to wildlife when such long-acting compounds are used, application of organophosphorous or carbamate insecticides may be used instead in areas where reapplication every few weeks is feasible. Fenthion and arprocarb are promising compounds for this purpose.


Further evaluation of the significance of urinary hydroxyproline determinations in the diagnosis of thyroid disorders.


Synthesis and secretion of immunoglobulins by established cell lines of human hematopoietic origin.


The allergic response of rabbit platelets. I. Membrane permeability changes.


The allergic response of rabbit platelets. II. Dependence on magnesium.


Bat immunoglobulins formed in response to experimental japan- ese B encephalitis (JBE) virus infection.


Antibody-producing cells in rabbits injected with soluble BSA. II. Kinetica and dose response.


The immunologic responses of the North American opossum (Didelphys virginiana).


Role of the thymus in tolerance. 8. Relative effectiveness of nonaggregated and heat-aggregated bovine gamma globulin, injected directly into lymphoid organs of normal rats, in suppressing immune responsiveness.


Disseminated intravascular coagulation. Heparin, anticoagulant and urokinase in experimental nephritic in mice.


Fluorescence studies on neural structures and endocrine cells in the pancreas of the cat.


Modifications in the neurosecretory system of the fish, Misgurnus fossilis, indiced by lasting inanition.


Symposium on reasearch and utilization of educational media for teaching the deaf. The history of America--a multi-media approach.


Seasonal changes in endocrine organs of the male common frog, Rana temporaria. I. The pars distalis of the adenohypophysis.


Intestinal lymphangiectasia with immunoglobulin A deficiency.


Pituitary function in haemochromatosis.

Pituitary function in haemochromatosis.


A familial study of procainamide-induced systemic lupus erythematosus. A question of pharmacogenetic polymorphism.


The binding of actinomycin D and F to bacterial DNA.


Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro.


Automated slide staining in haematology.


Histochemical demonstration of carbonic anhydrase activity.


Differentiating cells of chick embryo hemispheres: characterization and quantitative evaluation of the cell types and bulk preparation of enriched fractions.


Radioautographic, ultrastructural and biochemical studies on the effect of fluorouracil on the RNA synthesis in ther liver of rats.


Erythema nodosum migrans.

Erythema nodosum migrans.


Thermographic evaluation of patch-test and tuberculin reactions. A prelininary study.


Maintenance of delayed hypersensitivity reactions in patients receiving cancer chemotherapy.


Autoleucocyte sensitivity.

Autoleucocyte sensitivity.


Cellular changes in the psoriatic epidermis. VI. The submicroscopic intracellular distribution of mercury compound in the normal epidermis in comparison with that in the psoriatic epidermis.


Blood and urinary amino acid patterns in psoriasis.


Percutaneous absorption of corticosteroids. Adrenocortical suppression with total body inunction.


Skin homografts in rhesus monkeys (Macaca mulatta): first and second rejection. 1. Technical and clinical findings.


Skin homografts in rhesus monkeys (Macaca mulatta): first and second rejection. 2. Histology and histochemistry.


Skin homografts in rhesus monkeys (Macaca mulatta): first and second rejection. 3. The immunologically competent cells: electron microscopy and DNA synthesis.


Acanthosis nigricans in association with various genodermatoses. With emphasis on lipodystrophic diabetes and Prader-Willi syndrome.


Possible dermatropic virus associated with pityriasis rosea. Preliminary study.


Central nervous system involvement by mycosis fungoides.


Increased sebum secretion following selenium sulfide shampoos.


An evaluation of the anion exchange resin test for rapid diagnosis of porphyrinuria.


Autoradiographic study of DNA synthesis by epidermal cells in epidermodysplasia verruciformis.


Proteases and cutaneous blister formation.


Cutaneous horns. A clinical and histopathologic study.


Studies on a case of scleredema adultorum.


Malignant atrophic papulosis (Degos' syndrome). A case report.


A case of acute side-reactions to diaminodiphenylsulphone (DDS).


Treatment of gonorrhoea patients with intolerance to penicillin.


Streptomycin in the treatment of gonorrhoea in London in 1966.


Narcotic addiction with false-positive reaction for syphilis. Immunologic studies.


Characterization of a renal-dependent rat serum protein.


Is it insulin that is stained by aldehyde fuchsin and pseudoisocyanin in the sections of the pancreas?


The pathology of Adie's syndrome.

The pathology of Adie's syndrome.


"Hyaline degeneration" in severely atrophic muscle. Histochemical and electron microscopic observations.


Silver staining of the innervation of Meissner corpuscles in peripheral neuropathy.


An agar diffusion method for evaluation of antimycoplasma substances.


Composition of the rigid-layer of Streptomyces antibioticus producing peptide antibiotics.


Microbial transformation of peptide antibiotics. 3. Relationship of inducer structure to induction of actinomycin degrading enzymes in Actinoplanes missouriensis.


Effect of endogenous interferon and actinomycin D on growth of Japanese encephalitis virus in chick embryo cells.


Recurrent intussusception from metastatic melanoma.


Histochemical double staining method for simultaneous demonstration of acid and alkaline phosphatases on bone marrow smears.


RNA biosynthesis during differentiation of various cell types of chicken embryo in cerebral hemispheres. Histoautoradiographic study.


Studies on the organon vasculosum laminae terminalis. I. Comparative examination in teleost fishes (a morphological study).


An automatic device for sectioning analytical polyacrylamide gels: radioactive Escherichia coli 50 S ribosomal proteins.


Antibiotics as inhibitors of nucleic acid and protein synthesis.


Pathology of phycomycosis due to Entomophthora and Basidiobolus species.


Cardiac arrest following minor surgery in unrecognized thyrotoxicosis: a case report.


Pathogenesis of the glomerular lesions in aleutian disease of mink. Immunofluorescent studies.