Lysozyme in epiphyseal cartilage. 3. Effects of protamine, toluidine blue and histamine on mouse embryonic cartilage in organ culture.


Primary carcinoma in an artificial vagina.


Arterial degeneration and glomerular hyalinization in the kidney of monocrotaline-intoxicated rats.


Metastatic breast carcinoma of prostatic origin.


Dermatofibrosarcoma protuberans with metastases treated with methotrexate.


Rheumatoid factor and the fixation of complement.


Histamine-releasing activity of rheumatoid and nonrheumatoid serum and synovial fluid.


Rheumatoid factors and their biological significance. Summary.


Structural and conformational specificity of the antigen for rheumatoid factor.


Binding properties of monoclonal gammaG-antiglobulin factors with human gamma G.


Rheumatoid factors and the structure and function of gammaM antibodies.


Interactions among rheumatoid factors, gammaG antibodies, lymphocytes, and phagocytes.


Pharmacological responsiveness of the nasal mucosa.


Upper respiratory melanoma pathology and growth rate.


Distribution of radioactive dihydrostreptomycin in the cochlea. An autoradiographic study.


Carcinoma of the distal extrahepatic bile ducts: case report.


The 1969 Interim Meeting of the American Rheumatism Association.


Carcinogenic and noncarcinogenic polycyclic hydrocarbons in Neurospora crassa and Chinese hamster cells: their photodynamic effects.


Effect of hyperthermia on normal and neoplastic cells in vitro.


Histological, acetycholinesterase, and fluorescence histochemical studies on the atrial ganglia of the monkey heart.


The nucleoli in human thyroid cells.

The nucleoli in human thyroid cells.


Fertility control: health and educational factors for the 1970s. The future of oral contraception.


Craniosynostosis in Egypt.

Craniosynostosis in Egypt.


Hypersensitivity pneumonitis due to contamination of an air conditioner.


Hypersensitivity pneumonitis: "pandora's box".


Cell relationships in Hymenolepis diminuta.


Some helminth parasites of fishes of Bermuda and an account of the attachment organ of Alcicornis carangis MacCallum, 1917 (Digenea: Bucephalidae).


The structure and composition of the capsule of Trichinella spiralis in host muscle.


The arterial pulse in general paediatric practice.


Staining differences between normal and carcinogen-induced carcinomas of the hamster pouch.


Experimental histoplasmosis in embryonated eggs. II. Influence of the route of inoculation on the distribution of lesions.


Microsporum rivalieri isolated from tinea capitis in East Anglia (England).


Localization of plasma proteins in the human dental pulp.


Satellite cells of striated muscle after compression injury so slight as not to cause degeneration of the muscle fibres.


Histological and histochemical studies on the rhesus monkey (Macaca mulatta) olfactory mucosa.


The fine structure of the newborn rat adrenal cortex. I. Zona glomerulosa and Zona fasciculata.


The fine structure of the newborn rat adrenal cortex. II. Zona juxtamedullaris.


Seasonal variation in the structure and ultrastructure of the pituitary of the marine form (Trachurus) of the threespine stickleback, Gasterosteus aculeatus L. I. Rostral pars distalis.


Histological investigation of pituitary homotransplants in the marine form (Trachurus) of the threespine stickleback, Gasterosteus aculeatus L.


Seasonal variation in the structure and ultrastructure of the pituitary gland in the marine form (Trachurus) of the threespine stickleback Gasterosteus aculeatus L. II. Proximal pars distalis and neuro-intermediate lobe.


Fine structure of photoreceptor cells in the earthworm, Lumbricus terrestris.


Two-step attachment of Vi-phage I to the bacterial surface.


Editorial: on total patient care.

Editorial: on total patient care.


The first steps are crucial.

The first steps are crucial.


Characterization of African horsesickness virus.


Fibrosarcoma in a young chicken.

Fibrosarcoma in a young chicken.


The muscle relaxants and their antagonists.


Spores of microorganisms. 23. Interdependence of intra- and extra-cellular levels of calcium: its effect on the germination of bacterial spores in different media.


Specificity of the glutaraldehyde silver technique for catecholamines and related compounds.


Ocular toxoplasmosis.

Ocular toxoplasmosis.


Electron microscopy of protocollagen proline hydroxylase from chick embryos.


Glucocorticoid action on rat thymus cells. II. Interrelationships between ribonucleic acid and protein metabolism and between cortisol and substrate effects on these metabolic parameters in vitro.


Early detection--coordination of services--counseling are closing the gaps in nursing the handicapped child.


New curriculum of Pitt. The changing look in dental education.


Annual award presentation.

Annual award presentation.


Award to Dr. Cox.

Award to Dr. Cox.


Mitochondrial antibodies and subclinical liver disease.


Complement system in synovial fluids from patients with rheumatoid arthritis.


Giant cells, cartilage and bone fragments within rheumatoid synovial membrane: clinico-pathological correlations.


The anaemia of rheumatoid arthritis: the significance of iron deposits in the synovial membrane.


Heavy chain disease of the gamma (gamma M) type: report of the first case.


An evaluation of the importance of residual urine.


Cryosurgery for neoplasia.

Cryosurgery for neoplasia.


Cytochemistry of the human jejunal mucosa in the norm and in malabsorption syndrome.


The effect of albumin on the esterolytic activity of chymotrypsin.


Immunologic status of uremic patients.

Immunologic status of uremic patients.


Palliative radiotherapy in carcinoma of lung. I. Relief of occlusion of main bronchus.


Silver staining of collagen and reticulin fibres and crebral capillaries by means of physical development.


Light-microscopic demonstration of myoid fibrils in renal epithelial, mesangial and interstitial cells.


Electron cytochemical localization of cystine in plant cell walls.


Electron staining of synaptic vesicles using the Champy-Maillet technique.


Cardiac irritability secondary to sympathetic overactivity.


The proteins of cervical mucus and the influence of progestagens.


Diagnosis of vaginal discharges. Another approach to an old problem.


Hemimandibulectomy.

Hemimandibulectomy.


Immunological mechanisms in the pathogenesis of systemic lupus erythematosus.


Histochemical studies of Rhinosporidium seeberi.


Thyroid function tests in the newborn.

Thyroid function tests in the newborn.


Bone formation in cases of delayed fracture union and pseudarthrosis.


An ultrastructural organization of cartilage matrix as revealed through the use of lysozyme.


Intracellular calcium in epithelial, cartilage and bone cells.


Impregnation of canaliculi and other bone constituents with iodinated starch.


The ultrastructure of resorbing cell borders.


Chronic infusion of 5-fluoro-2'-deoxyuridine (5-FUDR) into the hepatic artery of the dog.


Thyroid and gastric autoimmunity in patients with diabetes mellitus.


Treatment of secondary hepatic tumours by ligation of hepatic artery and infusion of cytotoxic drugs.


Agent transmissible from Crohn's disease tissue.


Evaluation of iron supplements in prevention of iron-deficiency anaemia.


Mental symptoms in Parkinsonian patients treated with L-dopa.


Kidney transplantation for rapidly progressive glomerulonephritis.


Clinical assessment of apnoea-alarm mattress for newborn infants.


Hypothermia in a young man with an anterior hypothalamic lesion.


A etiology of Crohn's disease.

A etiology of Crohn's disease.


Hyperpermeable mucus in cystic fibrosis.


Autoantibodies in diabetes.

Autoantibodies in diabetes.


Congenital malformations.

Congenital malformations.


Keep on taking the tablets.

Keep on taking the tablets.


Architects look at health and welfare.

Architects look at health and welfare.


Housing the health service.

Housing the health service.


Carpometacarpal osteoarthritis of the thumb.


Swallowing after vagotomy.

Swallowing after vagotomy.


Smaller yet and smaller.

Smaller yet and smaller.


Experiences of medical care in the United States.


Peptic oesophagitis and oesophageal stricture.


Recruitment of women doctors for hospital service.


Asbestosis claim succeeds.

Asbestosis claim succeeds.


Fitness to plead.

Fitness to plead.


Tetracycline in renal failure.

Tetracycline in renal failure.


Aspirin and prednisone in microangiopathic haemolytic anaemia.


Work of the anaesthetist.

Work of the anaesthetist.


Heparin-exchange phenomenon.

Heparin-exchange phenomenon.


Parathyroid activity and postmenopausal osteoporosis.


Plasma-phosphate and tubular reabsorption of phosphate.


Drugs and congenital goitre.

Drugs and congenital goitre.


Complications of thyroidectomy.

Complications of thyroidectomy.


Tablet identification.

Tablet identification.


Contraceptives, brain serotonin, and liver tryptophan pyrrolase.


Headache and the eye.

Headache and the eye.


Desensitisation to horse-globulin before immunosuppressive treatment.


Subsequent malignancies in men with scrotal epithelioma.


Stereostethoscope.

Stereostethoscope.


L-dopa and oculogyric crises.

L-dopa and oculogyric crises.


Actinomycin-D treatment in a case of acute intermittent porphyria.


Altered antigenicity of cultured mononucleosis lymphocytes.


Methohexitone-assisted desensitisation for phobias.


Contamination of disinfectant solutions.


Medical advice for homosexuals.

Medical advice for homosexuals.


Obituary. Harold Williams Fullerton.

Obituary. Harold Williams Fullerton.


Eye on antibodies.

Eye on antibodies.


Ability of CBA mice to produce anti-idiotypic sera to 5563 myeloma protein.


Immunological paralysis induced by an idiotypic antigen.


Selective suppression of cell mediated immunity by equine anti-rabbit lymphocyte serum.


Axonal transport of neurotubule protein.


Ultrastructural changes during early development of retinal ganglion cells in Xenopus.


Chromosomal elements in elongating spermatid nuclei of grasshoppers.


Chromatophores and color change in the lizard, Anolis carolinensis.


Lipidosis of the basilar membrane.

Lipidosis of the basilar membrane.


Studies of the goitrogenic and oncogenic effect of thycapzol on C3H mice.


Haematoxylin--giemsa.

Haematoxylin--giemsa.


Relationships among scores on infant tests for children with developmental problems.


Abbreviated Gordon Musical Aptitude Profile with EMR children.


Identifying and modifying behavioral deficits.


Local amyloid deposits of the larynx. Electron microscopic studies of three cases.


Anatomy of the tracheal mucous glands in man.


Studies by quantitative immunoelectrophoresis on iron binding proteins in haemochromatosis.


Child development and pediatric office practice.


Microbiological oxygenation of alicyclic amides.


The microbiological oxygenation of acylated 1-adamantanamines. Stereochemistry and structural determinations.


Inhibition of sperm capacitation in vitro by contraceptive steroids.


Somatic translocation of antibody genes.


Absence of gamma-globulin receptors on mouse plasmacytoma cells.


Effect of arginine deficiency on synthesis of DNA and immunoglobulin receptor of Burkitt lymphoma cells.


Insect mortality.

Insect mortality.


In vitro lymphocyte stimulation by a soluble antigen from malignant melanoma.


Culture of human endometrium. II. Effects of estradiol.


Primary epidermal Paget's disease of the vulva.


Endometrial jet washer.

Endometrial jet washer.


The effects of acids upon the pathologic interpretation of the widths of the collagen bundles in bone.


The cutaneous porphyrias.

The cutaneous porphyrias.


The clinical porphyrias.

The clinical porphyrias.


Toxic hepatic porphyrias.

Toxic hepatic porphyrias.


The effect of succinylcholine during electrical stimulation of the urinary bladder.


Serum sodium and chloride in prostatic hypertrophy and cancer.


Migration of asbestos fibres from subcutaneous injection sites in mice. Crocidolite asbestos fibres, suspended in physiological saline, were injected subcutaneously into one or both flanks of 95 CBA/Lac female mice; 75 control mice received injections of saline only. Most animals were killed at chosen intervals of between 2 and 42 days after injection but some were left for longer periods of up to 623 days. At autopsy, many lymphoid and non-lymphoid structures were removed and examined for the presence of asbestos by the following techniques: haematoxylin and eosin staining followed by conventional and polarized light microscopy; Perl's stain; microincineration followed by phase-contrast microscopy; maceration with KOH followed by phase-contrast microscopy; and electron microscopy.A combination of haematoxylin and eosin staining and microincineration was found to be the most convenient and reliable method for demonstrating asbestos fibres in the tissues. Electron microscopy was essential for detecting very small fibres and for locating them to specific intracellular structures.The morphological findings indicate that some migration of asbestos fibres away from the initial site of injection takes place. Dissemination is usually along lymphatic pathways and fibres tend to accumulate in the lymphoid tissues, particularly in the regional (axillary) lymph nodes; smaller amounts were found in inguinal, mediastinal and lumbar nodes. The fibres were usually intracellular, lying inside the phagosomes of macrophages, but larger fibres weresometimes encountered lying free. Small numbers of fibres were seen in the spleen and also in non-lymphoid organs such as the liver, kidneys and brain-suggesting that some asbestos may enter the blood stream. There was no evidence of massive or selective spread to subserosal tissues in the thorax or abdomen, though trapping of asbestos fibres was observed in pleural "milky spots" in long-term survivors. The possible role of milky spots in the development of pleural plaques and mesotheliomata is discussed.


Serum immunoglobulins in retinal vasculitis.


Studies of the effect of immunoglobulin on rubella in pregnancy. Report of the Public Health Laboratory Service Working Party on rubella. Studies were done on 5,447 pregnant women given immunoglobulin after exposure to rubella and on 652 adult women similarly at risk but not pregnant and therefore not given immunoglobulin. The amounts of immunoglobulin, of known antibody content ranged from 750 mg. to more than 1,500 mg.; in a few second doses were given. Preinoculation blood samples from both groups showed that about 15% were still susceptible. Second blood samples were obtained from many of the women and nasal and throat swabs from as many index cases as possible. In the development of rubella by susceptible women a major factor was an index case in the same household. Whether judged on the serological evidence alone, or as a result of exposure to a confirmed index case, immunoglobulin in the amounts given did not appear to affect the incidence of rubella by comparison with the uninoculated group. Suppression of clinical manifestations attributable to immunoglobulin was possible in a few instances, but this could also have been an example of natural variation.


Serum reagins and leucocyte response in patients with house-dust mite allergy. A study was carried out on 26 patients with respiratory allergy due to the house-dust mite Dermatophagoides pteronyssinus and on 10 non-allergic control subjects using two in-vitro histamine release tests for assessing immediate-type allergy. The first test was on the patients' serum and assessed reaginic (anaphylactic; possibly IgE) antibodies by passive sensitization of normal human lung tissue. The second test was on the patients' leucocytes directly challenged with the mite antigen.Positive results were obtained in over 90% of patients, whereas the tests were either negative or very weakly positive in the control subjects. A significant degree of correlation was found between the two tests used, but pronounced differences were observed in a few instances.Confirmation of the role of IgE in tissue sensitization was obtained from tests with anti-IgE serum on leucocytes. Positive reactions of patients' leucocytes were also obtained with anti-IgG, anti-IgA, and anti-IgM sera, which would suggest that antibodies belonging to these immunoglobulin classes may also play a part in immediate-type allergic reactions.


Enzymograms of glycoprotein preparations from connective tissue.


The demonstration of immunoglobulins in porcine intestinal tissue by immunofluorescence with observations on the effect of fixation.


Recurrent respiratory tract infection due to isolated absence of IgA: report of a case.


The secondary antibody response in tissue culture. IV. Studies of the in vivo and in vitro antigenicity of native, aggregate-free and aggregated human gamma globulin in rabbits.


The immune response to (3-amino, 5-succinylaminobenzoyl)-p-aminophenylarsenic acid. Immunofluorescent studies of cells making anti-arsanilic acid antibody or anti-m-aminosuccinanilic acid antibody.


Intestinal secretion of immunoglobulins and antibodies to Escherichia coli in the pig.


Immunogenicity and specificity of collagen. IX. Resistance of different antigenic determinants of calf collagen to proteolytic treatment.


Significance of uterine lipofuscin in the squirrel monkey (Saimiri sciurea).


Lesions of the suprarenal glands in pre-eclampsia and eclampsia demonstrated in biopsy material.


The relationship between endometrial mast cell count and bleeding in women following insertion of an intrauterine device.


Free thyroxine index.

Free thyroxine index.


Effects of severe and marginal lipotrope deficiency on response of postnatal rats to infection.


Intravenous feeding as an aid to nutrition in disease.


Plasma kinin formation by complexes of aggregated gamma-globulin and serum proteins.


Semicontinuous screening of a whole community for hypertension.


Animal sources of common serotypes of Escherichia coli in the food of hospital patients. Possible significance in urinary-tract infections.


Diagnostic problems with innocent murmurs in children.


Intramuscular hyoscine in control of motion sickness.


Hyperparathyroidism in chronic renal failure. Assessment of autonomy by plasma-parathyroid-hormone response to alterations in calcium.


Effect of diabetes on migraine.

Effect of diabetes on migraine.


Selection of patients with pulmonary embolism for thrombolytic therapy.


Faecal antigen in viral hepatitis.

Faecal antigen in viral hepatitis.


Biotin-responsive propionicacidaemia.

Biotin-responsive propionicacidaemia.


Respiratory alarm monitor.

Respiratory alarm monitor.


Monitor for arterial line during haemodialysis.


Strokes and carotid occlusion.

Strokes and carotid occlusion.


Venereal disease.

Venereal disease.


More lessons from Red Lake.

More lessons from Red Lake.


Maternity services.

Maternity services.


Nasal cancer in woodworkers.

Nasal cancer in woodworkers.


Streptokinase for pulmonary embolism.

Streptokinase for pulmonary embolism.


Sources of Escherichia coli.

Sources of Escherichia coli.


Isolated cold abscess.

Isolated cold abscess.


VII. Hormonal control of calcium homoeostasis.


Goodbye junkies. A general practitioner takes leave of his addicts.


Systemic nocardiosis treated with trimethoprim and sulphamethoxazole.


Tests for syphilis in children for adoption.


Possible teratogenicity of trimethadione and paramethadione.


Tetracycline in renal failure.

Tetracycline in renal failure.


Increased blood-urea during phenformin therapy.


Toxicity of dithiothreitol.

Toxicity of dithiothreitol.


Training of chemical pathologists.

Training of chemical pathologists.


Complications of diabetes.

Complications of diabetes.


Swallowed neonatal endotracheal tube.

Swallowed neonatal endotracheal tube.


Super feeding?

Super feeding?


Alkalinising agents in the delivery room.


Herpesvirus type 2 infection and carcinoma of the cerivix.


Keep on taking the tablets.

Keep on taking the tablets.


Meiosis and testicular histology in XYY males.


Age-distribution of alpha-fetoprotein in hepatocellular carcinoma.


Lymphocyte abnormality in chronic mucocutaneous candidiasis.


Man against the giant hogweed.

Man against the giant hogweed.


Ineffectiveness of gamma-globulins in acute leukaemia.


Hysteria and schizophrenia.

Hysteria and schizophrenia.


An appeal to eye specialists.

An appeal to eye specialists.


Carpometacarpal osteoarthritis of the thumb.


James Harold Conyers M.A., M.B. Cantab., F.R.C.S.


Robert James Phillips M.B.E., M.B., B.Sc. Wales, M.R.C.P.G.


Fate of inducer during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture. II. Levels of intracellular polycyclic hydrocarbon during enzyme induction and decay.


Postoperative management of arrhythmias and low cardiac output in patients undergoing aortic valve surgery.


Human reaginic antibodies.

Human reaginic antibodies.


Dietary treatment of inborn errors of metabolism.


A review of 23 human lung transplantations by 20 surgeons.


Toluidine blue technique.

Toluidine blue technique.


Transmissible gastroenteritis (TGE) of swine: canine serum antibodies against an associated virus. Sera of weaned puppies from a hysterectomy-derived, specific pathogen free (SPF) closed dog colony did not contain antibodies against a TGE-associated virus or a serologically related one, but sera from puppies and older dogs from open kennels did. The higher antiviral titers in serum of older dogs suggested that these animals had suffered either persistent or recurrent infections. Seventy-two puppies had no contact with swine, indicating that the virus was able to propagate independently of contact with swine.


Ultraviolet inactivation of the infective agent of Aleutian disease of mink. An experiment carried out to examine the effect of ultraviolet light on the aleutian disease agent in serum indicated that the agent was sensitive to irradiation.


Gonadoblastoma. A review of 74 cases.

Gonadoblastoma. A review of 74 cases.


Immunoglobulin-containing cells in non-tropical sprue.


Electron microscopic study of lipopolysaccharide from an avian strain of Escherichia coli O18. The fine structure of lipopolysaccharide (LPS), isolated from an avian strain of Escherichia coli O18, was examined by electron microscopy. In positively stained preparations, ribbonlike structures with frequent branching were observed as previously reported (4). Two densely stained parallel lines were occasionally seen associated with a ribbon. When negative staining was employed, the LPS appeared as a branching ribbon with one central and two lateral zones divided by two relatively dense parallel lines running the complete length of the ribbon. The lateral zones were probably due to the O-antigenic side chains of the LPS. This interpretation was supported by the fact that the electron microscopic structure of the LPS from two rough strains, E. coli K-12 Gal 23 and Salmonella tuphimurium TV119 RII, both lacking the O-specific side chains, did not possess the outer lateral zones.


cis-Dichlorodiammineplatinum(II): cytological changes induced in Escherichia coli. Filamentous forms of Escherichia coli, induced by growth in the presence of cis-dichlorodiammineplatinum(II), contain amorphous inclusion aggregates, possibly ribosomal, with an affinity for uranium ion.


Fasting hypoglycaemia and metabolic acidosis associated with deficiency of hepatic fructose-1,6-diphosphatase activity.


Antilymphocyte-serum preparations in treatment of renal-allograft rejection.


Effect of L-dopa on seborrhoea of parkinsonism.


Headache and the eye. A community study.


Chromosomal anomalies in spontaneously aborted human fetuses.


Ultrastructural evidence for regeneration of heart--muscle cells after experimental myocardial infarction.


Chemical basis of epilepsy.

Chemical basis of epilepsy.


Dual-purpose cannula.

Dual-purpose cannula.


Portable ventilator-incubator.

Portable ventilator-incubator.


Management of megaloblastic anaemia.

Management of megaloblastic anaemia.


Cooling off.

Cooling off.


Is lyonisation total in man?

Is lyonisation total in man?


Clinical haematology.

Clinical haematology.


Diabetic retinopathy.

Diabetic retinopathy.


The giant hogweed.

The giant hogweed.


The second Green-Paper.

The second Green-Paper.


The psychiatric component in general practice.


Tetracycline in renal failure.

Tetracycline in renal failure.


Ethics and experimentation.

Ethics and experimentation.


Service platform for intensive-care units.


Orange soles.

Orange soles.


Training of anaesthetists.

Training of anaesthetists.


Work of the anaesthetist.

Work of the anaesthetist.


The distending force in the production of communicating syringomyelia.


Medical care in North Vietnam.

Medical care in North Vietnam.


Diagnosis of destructive lesions of the pineal.


Treatment of primary polycythaemia.

Treatment of primary polycythaemia.


A case of beta-xylosidase deficiency.

A case of beta-xylosidase deficiency.


Glanzmann's disease and trait.

Glanzmann's disease and trait.


Argininosuccinase activity in amniotic-fluid cells.


Red-cell triosephosphate isomerase and chromosome 5.


Detection of methicillin resistance in cultures of Staphylococcus aureus.


Value of the silver swaddler in preventing evaporative heat-loss.


Small-molecular-weight cytotoxic factor in cholera toxin.


Psychogeriatric assessment unit.

Psychogeriatric assessment unit.


Hospital beds and cigarette smoking.

Hospital beds and cigarette smoking.


Incidence of blood-group B in myocardial infarction.


Age-distribution of cancers caused by obstetric x-rays and their relevance to cancer latent periods.


Consumption of coagulation material by heparin.


Alpha rhythm.

Alpha rhythm.


Diagnosis of brucellosis.

Diagnosis of brucellosis.


Glucose and fat tolerances in Bantu children.


Lithium depletion and atherosclerotic heart-disease.


Karl Henrik Koster, M.D. Copenhagen.

Karl Henrik Koster, M.D. Copenhagen.


Making the best use of the blackboard.

Making the best use of the blackboard.


Intrinsic-factor antibodies in absence of pernicious anaemia. 3-7 year follow-up.


The effect of cytostatic therapy with cyclophosphamide alone or in combination with methotrexate on the phytohaemagglutinin lymphocyte culture and on the immunoglobulins.


Antagonistic effects of excitation and interval on tension in guinea pig atria.


Faculty member honored for contribution to dental teaching aids.


Aortic arch atresia with transposition of the great vessels: physiologic considerations and surgical management.


Secretory ependymoma of the filum terminale.


Role of spermatogonia in the repair of the seminiferous epithelium following x-irradiation of the rat testis.


An ultrastructural study of human eosinophil granules: maturational stages and pyroantimonate reactive cation.


Ultrastructural studies on cleavage stage t12-t12 mouse embryos.


Striated muscle in the lung.

Striated muscle in the lung.


Lipofuscin pigment in neurons of young mice with a hereditary central nervous system defect.


Fine structure of the hamster sperm head.


Lysozyme-dependent production of spheroplast-like bodies from polymyxin B-treated Salmonella typhimurium.


Illustrated lectures.

Illustrated lectures.


Pathophysiology of the fluid systems of the inner ear.


Symptomless haematuria in childhood.

Symptomless haematuria in childhood. The clinical, laboratory, and renal biopsy findings in 47 children with symptomless haematuria are reported. In 41 the haematuria was recurrent. Local causes were excluded by means of intravenous urography, which was normal in all but one child, who had a horseshoe kidney.Since all the patients had presented in a similar manner they were classified into four groups according to the severity of glomerular changes on renal biopsy. In group I the glomeruli were optically normal. In group 2 they showed a variable degree of mesangial thickening with absent or minimal cellular proliferation. In group 3 there was diffuse mesangial thickening and proliferation-an appearance indistinguishable from that of subsiding post-streptococcal glomerulonephritis. Compared with groups 1 and 2, more patients in this group had persistent proteinuria, as well as evidence of streptococcal infection preceding the initial haematuria. Only two patients showed severe proliferative glomerulonephritis on biopsy (group 4); both had heavy proteinuria and one repeatedly had low serum beta1(c)-globulin levels.


Effects of median nerve injury on some digital tissues of the hand of the macaque (Macaca fascicularis).


The role of NZB-NZW F1 thymus in experimental tolerance and auto-immunity.


In vivo LE cell formation in synovial fluid.


Some properties of five new Salmonella bacteriophages. Five bacteriophages were isolated from lysogenic strains of Salmonella potdam. On the basis of plaque morphology, thermostability, serology, host range, one-step growth parameters, and phage morphology, they were divided into three groups: group A, phages P4 and P9c; group B, phages P3 and P9a; and group C, phage P10. Group A phages had a hexagonal head 55 nm in diameter with a short tail 15 nm long. These phages were particularly characterized by high thermostability, lack of serological relationship with any of the other phages, and restriction of lysis to other Salmonella strains of Kauffmann-White group C(1). Group B phages had a head identical in size and shape to that of the A phages, but they possessed a tail 118 nm long with a contractile sheath. A unique feature was the occurrence of tail fibers at the end of the core rather than at the base of the sheath. These phages were considerably less thermostable, had extended host ranges, and were serologically distinct from each other but unrelated to the A phages. The group C phage, P10, had a head identical to that of the A and B phages. It had a tail 95 nm in length, with tail fibers attached to a base plate at the end of a contractile sheath. P10 was highly sensitive to heat, lysed only smooth strains of Salmonella, and showed a degree of serological relationship to both B phages. The relationship of these phage groups to previous Salmonella phage grouping schemes is discussed.


Morphological variants of coliphage P1.

Morphological variants of coliphage P1. Lysates of P1 from all hosts tested contained at least three morphological variants with respect to head size. These were termed "big" (P1B), "small" (P1S), and "minute" (P1M). Since successive clonings of plaques isolated on many different hosts failed to change the proportions of the variants, we concluded that the production of variants was a function of the P1 genome rather than that of the host. In the electron microscope, the heads appeared to be icosadeltahedra, having face-to-face head diameters of 86 +/- 2 nm, 65 +/- 2 nm, and 47 +/- 2 nm. Assuming the head capsids to be composed of the same protein subunits, these diameters were compatible with T = 16, 9, and 4 with a lattice constant (intercapsomere distance) of 12 to 13 nm. The tails of all variants were morphologically indistinguishable. Each consisted of a hollow tail tube surrounded by a contractile sheath attached to the head by means of a "head-neck connector" which could be a specialized vertex capsomere. In CsCl gradients, a number of bands were observed. One band contained the majority of P1B particles and 99% of the plaque-forming units. Two other bands contained P1S particles whose densities suggested a content of about 40 and 60% of the complete P1B genome. The less dense of these two bands also contained defective P1B particles with a calculated content of only 60% of the complete genome. The P1S particles tested injected their deoxyribonucleic acid (DNA) into host cells and killed them. Genetic markers contained in this band could be rescued by infectious P1B particles, confirming the evidence of Ikeda and Tomizawa that this fraction contains P1 DNA.


Comparative studies with tox plus and tox minus corynebacteriophages. The characteristics of nine inducible temperate corynebacteriophages designated alpha(tox+), beta(tox+), P(tox+), gamma(tox-), pi(tox+), K(tox-), rho(tox-), L(tox+), and delta(tox+) have been compared. Virion morphology and ability to recombine genetically with the well-studied phage beta(tox+) have been correlated with other properties of the phages, and the distribution of the genetic marker tox+ among related and relatively unrelated corynebacteriophages has been analyzed. The immunity specificity, host range, and plaque morphology of each phage were determined. The phages can be separated into five groups with different immunity specificities. Each type of host range previously recognized in mutants of phage beta(tox+) was present in one or more of the phages included in the present study, and the phages were found to produce plaques of several different morphological types. Representative phages with each of the five types of immunity specificity were further characterized with respect to virion morphology, ability to recombine with phage beta(tox+), latent period, average burst size, and neutralization by homologous and heterologous antiphage sera. All of these phages have polyhedral heads and long slender tails, but two distinct morphological types were distinguished by the sizes and proportions of the components of the virions. Only phages of the same morphological type as beta(tox+) were capable of genetic recombination with beta(tox+), but morphological similarity between phages was not sufficient to insure interfertility. The phages which recombined with beta(tox+) resembled one another in plaque morphology, latent period, and average burst size, whereas phages which failed to recombine with beta(tox+) differed in these characteristics. The phages capable of genetic recombination with beta(tox+) were found to differ from each other in immunity specificity, host range, neutralization by antiphage sera, and toxinogenicity. Thus, these latter characteristics are of limited value in establishing the extent of relatedness between corynebacteriophages. The genetic marker tox+ was not consistently correlated with any other property of the corynebacteriophages analyzed in this study. The most striking finding regarding the distribution of the tox+ marker is its presence both in beta(tox+) and delta(tox+), phages which fail to recombine genetically and which differ in virion morphology. The presence of the tox+ marker in genetically unrelated corynebacteriophages poses many questions concerning the origin(s) of tox+ and the evolution of the phage-host interactions which determine the ability of corynebacteria to synthesize diphtherial toxin.


Stalked bacteria: properties of deoxriybonucleic acid bacteriophage phiCbK. The Caulobacter crescentus bacteriophage phiCbK was studied with respect to the physical and chemical properties of both the phage and its deoxyribonucleic acid (DNA). Electron micrographs reveal the phage to be among the largest DNA bacteriophages reported, with head dimensions of 64 by 195 nm and a flexible tail 275 nm in length. The phage is composed of 57% DNA. This DNA is double-stranded as indicated by (i) the sharp increase in extinction coefficient over a narrow range of temperature increase, (ii) an increase in density in CsCl upon thermal denaturation, and (iii) the equivalence of guanine and cytosine as well as adenine and thymine, determined by chemical analysis. phiCbK DNA cosediments with Escherichia coli phage T2 DNA and has therefore been assigned an S(20,w) value of 63.5S. The size of the phage and its DNA and the percentage of DNA indicate that the phiCbK phage head is relatively loosely packed. The properties of the DNA from bacteriophage phiCbK are similar to those of host C. crescentus DNA with respect to buoyant density, thermal transition point, and guanine plus cytosine content.


Morphogenesis of Bittner virus.

Morphogenesis of Bittner virus. The morphogenesis of Bittner virus (mouse mammary tumor virus) was studied in sectioned mammary tumor cells. Internal components of the virus (type A particles) were seen being assembled in virus factories close to the nucleus and were also seen forming at the plasma membrane. The particles in virus factories became enveloped by budding through the membrane of cytoplasmic vacuoles which were derived from dilated endoplasmic reticulum. Complete virus particles were liberated from these vacuoles by cell lysis. Particles budding at the plasma membrane were released into intercellular spaces. Maturation of enveloped virus occurred after release, but mature internal components were rarely seen in the cytoplasm before envelopment. Direct cell-to-cell transfer of virus by pinocytosis of budding particles by an adjacent cell was observed, and unusual forms of budding virus which participated in this process are illustrated and described. There was evidence that some virus particles contained cytoplasmic constituents, including ribosomes. Certain features of the structure of internal components are discussed in relation to a recently proposed model for the internal component of the mouse leukemia virus. Intracisternal virus-like particles were occasionally seen in tumor cells, but there was no evidence that these structures were developmentally related to Bittner virus.


Operating room forum. Four separate sponge counts needed to ensure accuracy.


A thyroid suppression test using a single dose of L-thyroxine.


Clotting changes, including disseminated intravascular coagulation, during rapid renal-homograft rejection.


Immunoglobulins in tropical sprue.

Immunoglobulins in tropical sprue.


Staining and electron microscopic characteristics of amine-storing cells in rat's gastric mucosa.


Pseudo-malignant cutaneous amoebiasis.

Pseudo-malignant cutaneous amoebiasis.


Development of immunoglobulins and malarial antibodies in Nigerians.


Hepatotoxicity of Senecio abyssinicus. Experimental and ultrastructural studies.


Fluorescent antibody tests applied to serum of patients with Gambian sleeping sickness.


Anti-gamma-globulins in women treated with anti-Rh gamma-globulin.


Mucosubstances in normal and in neoplastic mast cells of the dog.


Effect of 2-thio-6-azathymine on the structure of glandula submaxillaris and other salivary glands.


Immunologic properties of alkaline phosphatase from human placenta and membranes at delivery.


Sulphated groups in human salivary proteins: a comparative histochemical and chemical study.


The use of cryosurgery in the control of locally recurrent tumours. Cryosurgery was used as a mode of treatment in 31 patients with advanced tumours.The patients were selected because of failure of other forms of conventional treatment or because a less radical type of therapy was advisable.The primary aim of the treatment was palliation. Pain was well controlled in almost all patients in whom the main bulk of the tumour could be successfully destroyed. Bleeding was also controlled temporarily and obstruction prevented in other patients.Cryosurgery is a simple procedure, easy to perform, has very few complications and can be repeated at frequent intervals. It is well tolerated by the elderly patients and produces very little postoperative discomfort, permitting earlier discharge from hospital.In selected cases of cancer, cryosurgery has a definite role to play in improving the quality of survival. It is particularly useful in extensive and recurrent cancers of the head and neck region.


Prevention of Rh immunization.

Prevention of Rh immunization.


Education.

Education.


Changes in concentration of plasma proteins associated with Marek's disease.


So you're going to give a talk?

So you're going to give a talk?


The mast cells of Gallus domesticus. II. Histochemistry.


Visual systems--pro and con.

Visual systems--pro and con.


Application of audiovisual technology in medical education.


Audiovisuals in medical education: standardization--the consumer's viewpoint.


Audiovisuals in medical education: standardization--the manufacturer's viewpoint.


The use of audiovisuals in clinical teaching. The input requirements.


Some thoughts on a national audiovisual delivery system.


Audiovisuals in teaching hospitals--are materials relevant to the job?


Audiovisuals in teaching hospitals--to better use the tried and true.


Audiovisuals in teaching hospitals--the VA and AV.


Can audiovisuals satisfy the demand for individualized continuing education?


Communications in postgraduate medical education.


Regional medical program applications of instructional media in continuing education.


Audiovisuals as media for continuing education in the hospital setting.


Basic science education and audiovisuals.


The use of audiovisuals in clinical teaching.


Audiovisuals in teaching hospitals--report of hospital study.


Report of the needs in continuing education. Panel session.


National Conference on the use of audiovisuals in medical education--summation and recommendations.


Experimental syphilis in the chimpanzee. Immunoglobulin class of early antibodies reactive with Treponema pallidum.


Immunoglobulins and antibodies in gallbladder bile.


Application of enzyme kinetics to a problem in pharmacology: receptor affinities and efficacies in the action of morphine and related drugs on human serum esterase.


Isoelectric focusing of Trypanosoma brucei subgroup antigens in polyacrylamide gel thin layers. A method for resolving and characterising protein-carbohydrate complexes of an enzymic and immunological nature.


Thin-layer gel filtration of modified proteins on 4 per cent fine pearl-condensed agar.


Ultrastructural study of human myeloma cells in relation to its function. The ultrastructure of neoplastic plasma cells from a patient with prolonged multiple myeloma was studied in relation to its function, that is, the secretion of immunoglobulin light chain. Peroxidase-labelled antibodies, each monospecific to its immunoglobulin component chain, were used to localize intracellular immunoglobulin within myeloma cells under the electron microscope. By this method, only the kappa type light chain was detected within myeloma cells in bone marrow tissue of this patient, indicating that the occurrence of free kappa type light chains in serum and urine was due to the cessation of heavy chain synthesis within the myeloma cells. The kappa chain was demonstrated as conspicuous electron-dense precipitates in ergastoplasm, its cisternal space, external layer of nuclear membrane, and ribosomes associated with ergastoplasm and nuclear membrane. No immunoglobulin was demonstrated in an atypical Golgi complex, an organelle which is ordinarily engaged in protein synthesis. Numerous crystalline structures and similar inclusion bodies found in myeloma cells appeared to have arisen from the Golgi area, but they did not ever react with the peroxidase label. Discharge of the kappa chain from the cell seems to be carried out through cell fragmentation, possibly caused by progressive distension of the ergastoplasmic cavity.


Paneth cells in diverticular disease of the colon. Paneth cells were found in the mucosa of the sigmoid colon in 13 out of 27 cases of diverticulosis and diverticulitis. It is concluded that their appearance at this site is a non-specific reaction to injury.


A direct staining technique for amylase isoenzyme demonstration.


New normal ranges for the radioiodine uptake study.


Some further observations on microgliomatosis.


A technique for the electron microscopy of protein-free particle suspensions by the negative staining method.


T3 thyrotoxicosis. Thyrotoxicosis due to elevated serum triiodothyronine levels.


Results of surgical treatment of occlusive arterial disease affecting the lower limbs, 1953-1967.


The use of continuous progestogen contraception in the treatment of migraine.


Recent laboratory evidence of benefits from injection therapy for pollinosis.


The use of disodium cromoglycate in the treatment of asthma.


Immunoglobulin E in allergic disease.

Immunoglobulin E in allergic disease.


The use of immune serum globulin (gamma globulin).


Drug therapy. V. Oral anticoagulant therapy.


The galloping ghost of Gauss and the normal radioidine uptake.


A crystallographic investigation of the Mcg myeloma protein. ANL-7635.


Studies on the development of mid-gut of the tribolium castaneum adult. ANL-7635.


Treatment of granuloma telangiectaticum with 0.2 per cent fluocinolone acetonide cream.


The post-treatment disappearance of reactivity to treponemal and lipoidal tests in early syphilis.


Local action of intrahypophyseal implants of estrogen as revealed by staining with peroxidase-labeled antibody.


Human choroid plexus: morphologic and histochemical alterations with age.


An antigenic and serologic comparison of two virulent strains and an attenuated strain of Anaplasma marginale.


Modification of Field's stain for examination of growth forms of Babesia gibsoni.


Pathologic changes of placentas from heifers with experimentally induced epizootic bovine abortion.


The thymus, a lymphatic and epithelial organ of the snake (Vipera berus).


A study of the mastocytolytic effects of polycations in the presence of certain plasma substitutes.


Genetic markers of rabbit immunoglobins.


EMG changes induced by antibiotics.

EMG changes induced by antibiotics.


Serum protein bound iodine (PBI) estimation in the acne vulgaris (preliminary study).


Reactive lysis: the complement-mediated lysis of unsensitized cells. I. The characterization of the indicator factor and its identification as C7. This paper describes the characteristics of the indicator factor (I) which takes part in reactive hemolysis and its identification as the seventh component of complement. I was shown to be a beta globulin with a sediment coefficient of 5.7S and a molecular weight of about 140,000. Experiments on the depletion of I activity with anti-I antiserum or with activated R euglobulin showed that I was a late acting complement component necessary for the lysis of cells after the EAC142 stage. Complement component analysis of purified I fractions excluded all known components except C7. The physicochemical characteristics of I are compatible with published data on C7. The method of quantitation described represents a convenient method of testing for C7.


Reactive lysis: the complement-mediated lysis of unsensitized cells. II. The characterization of activated reactor as C56 and the participation of C8 and C9. It has been shown that the "activated reactor" that is produced in certain human sera by complement activation is a stable complex of the fifth and sixth component of complement (C56). On interaction with C7, the indicator factor, a complex C567 is formed which for a short time (half-life less than 1 min) has an activated binding site and can attach itself to normal red cell membranes, conferring on them the hemolytic properties of the "heat stable" complement intermediate EC 1 approximately 7, the capacity to be lysed by C8 and C9. These cells have neither antibody nor the complement components up to C3 bound on them. The binding site-activated C567c-can similarly bind to other hydrophobic surfaces, including agarose gel where it forms a "stainable line". If the complex is not bound to a surface, the binding site decays and the resulting complex will no longer give rise to lysis. However it will still inactivate C8 and C9 in solution. The sera that can generate activated reactor apparently do so because they have an excess of C5 and C6, compared to their content of C7. The phenomenon of reactive lysis thus represents complement-mediated lysis of unsensitized cells initiated at the C5 stage by a stable complex (C56) which was generated by complement activation at a distance. The immunochemistry of the phenomenon is described and some of its implications discussed.


Interactions of the complement system with endotoxic lipopolysaccharides in immunoglobulin-deficient sera. Bacterial lipopolysaccharides (LPS) derived from a variety of organisms effectively induced C consumption in humans, bovines, and porcines with developmental agammaglobulinemia; birds with experimental agammaglobulinemia; and humans with agammaglobulinemia syndromes. This interaction proceeded even in precolostral piglet sera which contained less than 2.5 x 10(-6) mg/ml gamma globulin, and led to generation of neutrophil chemotactic factor and anaphylatoxin in these sera. Hence, the LPS-C interaction can proceed in sera markedly deficient in immunoglobulin. The question of whether immunoglobulins can be bypassed in the LPS-C interaction, or whether they are regularly utilized in a way so efficient that their participation is masked, was considered.


A histochemical study of glucose 6-phosphate dehydrogenase in skin biopsies of normotensive and hypertensive patients.


Nephrotoxic serum nephritis. I. Chemical, morphologic, and functional changes in the glomerular basement membrane during the evolution of nephritis.


Ultrastructural modifications of intercellular junctions in some epithelial tumors.


Pathology of the nephrotic syndrome in children: a report for the International Study of Kidney Disease in Children.


Analgesic abuse in psychiatric patients.


Relation between residual urine volume and response to treatment of urinary infection.


Antenatal diagnosis and aminoacid composition of amniotic fluid.


Fall of endocardial potentials after acute myocardial infarction.


Ovarian suppressants in dogs: pilot study of an approach to rabies control.


Glucagon in resistant heart-failure and cardiogenic shock.


Effect of smoking on blood-clotting and lipid and lipoprotein levels.


The future of primary care.

The future of primary care.


Evidence of altered antigenicity in cultured lymphoid cells from patients with infectious mononucleosis.


Ulcerative colitis and Crohn's disease.

Ulcerative colitis and Crohn's disease.


Polar medicine.

Polar medicine.


Variant angina with normal coronary arteriogram.


Glucose-6-phosphate-dehydrogenase deficiency and age.


Medical relief in the Nigerian civil war.


Measurement of drug effects.

Measurement of drug effects.


Alpha-fetoprotein in Greece and France.

Alpha-fetoprotein in Greece and France.


The alpha-fetoprotein test in pregnant women, women on oral contraceptives, newborn babies, and pyridoxine-deprived baboons.


L-dopa with MK 485 for depression.

L-dopa with MK 485 for depression.


Intravascular coagulation in acute hepatic necrosis.


Method for increasing the sensitivity of radial-immunodiffusion assay.


Traumatic haemoglobinuria in conga-drum players.


Erythrocyte carbonic-anhydrase-B levels in thyroid disorders.


Social class and biological tests.

Social class and biological tests.


E.E.G. technicians.

E.E.G. technicians.


Effect of starvation on renal function.

Effect of starvation on renal function.


Gastrointestinal bleeding: a rate of progress.


Acute leukaemia and Turner's syndrome.

Acute leukaemia and Turner's syndrome.


Plasma-phosphate and tubular reabsorption of phosphate.


Neonatal hypoglycaemia, hyperinsulinism, and absence of pancreatic alpha-cells.


Encephalomyelitis and enteroviruses.

Encephalomyelitis and enteroviruses.


Hormones and the XYY male.

Hormones and the XYY male.


Ascorbic-acid treatment for osteogenesis imperfecta.


John Edward French. D.M., D.Phil. Oxon., M.R.C.Path.


The prismatic world of operating room nursing.


Training student nurses in theatre.

Training student nurses in theatre.


Nursing care of the neonate requiring surgery for congenital defects.


Ophthalmic nursing: the gentle touch.

Ophthalmic nursing: the gentle touch.


The investigation and treatment of hyperthyroidism.


Aeromedical consultation service case report: early manifestations of multiple sclerosis.


A study of extradural medication in the relief of the lumbosciatic syndrome.


Alcoholic toluidine blue: a rapid method for staining nuclei in unfixed mycetozoa and fungi.


A histochemical study of the composition of spore ornamentations in operculate discomycetes.


Caudal epidural analgesia in lumbosciatic pain.


The structure rule of antibodies and the antibody problem.


Immunoglobulin responses in rubella and its complications. Normal responses of rubella-specific IgG and IgM antibody were assessed in eight patient by immunofluorescence. A prolonged rubella-specific IgM response was shown in three patients with complications of rubella infection. Two patients had thrombocytopenic purpura and one had carpal-tunnel compression.


Hyperglobulinaemic renal tubular acidosis: a report of nine cases. Of nine women with hyperglobulinaemic renal tubular acidosis four presented with acidosis and five had the "incomplete" form of the disorder. Seven patients had nephrogenic diabetes insipidus, but none had the Fanconi syndrome. Investigation showed abnormal immunoglobulins and autoantibodies in all nine patients. Diseases coexisting with renal tubular acidosis were Sjögren's syndrome, hyperglobulinaemic purpura, autoimmune liver and thyroid disease, diffuse pulmonary fibrosis, and a peripheral neuropathy. It is suggested that this type of renal tubular acidosis might be due to an autoimmune process.


Folic acid deficiency secondary to a diet for maple syrup urine disease.


Virus infections of the fetus and newborn infant.


An immunochemical method for serum alpha-globulin. Quantitative determination by micro-ouchterlony double diffusion.


Studies of plasma beta-globulin: sex difference and effect of ethinyl estradiol and testosterone.


Sensitivity to house-dust mites in atopic dermatitis.


Cold urticaria. Immunologic studies.

Cold urticaria. Immunologic studies.


Primary pulmonary hypertension.

Primary pulmonary hypertension.


Pityriasis rosea--an autoaggressive disease? Statistical studies in relation to aethiology and pathogenesis.


Autoimmune hemolytic anemia. Natural history and viral-immunologic interactions in childhood.


Radio-isotope scanning in the diagnosis of pancreatic disease.


Polygraphic recording of several physiological parameters of speech.


Reflections on the diagnostic value of average evoked potentials in deep coma.


Study of the respiratory frequency during sleep in relation to the amplitude of the R wave of the ECG.


Effect of experimental sensory deprivation on going to sleep.


Night sleep of acute manic or depressive episodes during their evolution.


The use of the statistical amplitude analyser in cerebral pharmacodynamics: the action of Immenoctal (secobarbital).


The effects of intracarotid gas embolism on the cerebral blood flow in the baboon.


EEG changes during acute intoxication with trichlorethylene.


Value of the EEG in acute intoxications in children.


Geographical variations in the photo-sensitivity of the baboon.


Presence and relevant proportions of early irritative foci in children after benign or apparently benign cranio-cerebral trauma.


Study of the photo-sensitivity of Papio anubis, Papio cynocephalus and of their cross-mating.


Attempt at automation of conventional EEG analysis.


From epilepsy to the epileptic: a tele-EEG study of adult epileptic subjects.


Asynchronous, bitemporal, inter-ictal EEG abnormalities in unilateral epilepsies.


Studies on spike and wave discharges in man. II. Clinical and EEG aspects of myoclonic absences.


Clinical EEG and EMG correlations in the abdominal attacks of the child.


Polygraphic investigation of sleep in cerebral circulatory insufficiency.


The EEG in halothane-induced hypertension.


Persistent electroencephalographic and behavioural changes following nitrazepam and amylobarbitone.


Electroencephalographic investigation in acute drug poisoning.


Evoked cerebral sensory responses in the assessment of surviving function in cerebral disaster.


Simultaneous analysis of potentials evoked by focal illumination of two retinal areas by flicker and pattern stimuli; application to migraine and to visual field investigations.


EEG prediction of outcome after resuscitation from cardiac or respiratory arrest.


Visually evoked responses to patterned stimuli in different octants of the visual field.


Recording of evoked responses and contingent negative variation in routine electroencephalography.


Cortical evoked potentials in patients with benign essential myoclonus and progressive myoclonic epilepsy.


Measuring and recording EEG topography.

Measuring and recording EEG topography.


Variability of visual evoked responses in the human newborn.


Intracerebral events in humans related to real and imaginary stimuli.


The effect of attention on the average evoked response to speech sounds.


Mono-amine oxidase inhibitors, sleep and mood.


The relationship between barbiturate-induced activities in the cerebellum and the red nucleus of the rabbit.


Influence of the septum and inferior colliculus on medial geniculate body units.


Sleeping sickness: sleep study of a case.


An automatic sleep analyzer.

An automatic sleep analyzer.


Study of neurophysiological mechanisms of human mental activity.


Available oxygen in the human deep brain structures during some types of mental activity.


Organization of cerebral electrical activity and the process of optimal control of central nervous system activity.


Central cholinergic effects on the electrosubcorticogram and on muscle tone in Parkinsonian patients.


Steady potential and EEG in man during temperature changes in the trigeminal area.


Steady potentials and evoked responses in the visual areas.


Steady potential and electrical activity of the anterior hypothalamus during stimulation of peripheral thermoreceptors.


Effect of adrenocortical and ovarian hormones on cerebral electrical activity.


New data on the electrogenesis of cortical primary responses.


Use of analogue computer techniques for electrophysiological data processing.


Modelling of electrophysiological phenomena with regard to interrelation between some brain structures.


Analogue method for amplitude-frequency EEG evaluation.


On evaluation of amplitude changes in the main human EEG rhythms in response to sensory stimulation.


The importance and scope of EEG in the neurosurgery of expansive process.


Bioelectric activity and haemodynamics during drug effects in hypotonic patients.


Electrical and physio-pathological problems of petit mal.


Significant electroencephalographic patterns in the detection and follow-up of cranio-cerebral traumas and encephalitides.


EEG and psychiatry.

EEG and psychiatry.


EEG and behaviour.

EEG and behaviour.


EEG in psychopathology.

EEG in psychopathology.


EEG signs of cerebral tumours and cerebral vascular accidents.


Regulatory centres of the EEG in sleep and wakefulness.


Bioelectrical activity in the experimental animal; death and the EEG.


EEG in organic psychosis.

EEG in organic psychosis.


EEG in acute vasomotor anoxia (syncope).


Experience in the treatment of atypical forms of petit mal with diazepine derivatives.


Round table on epilepsy.

Round table on epilepsy.


Some observations on alcoholic epilepsy.


The problem of the interpretation of temporal EEG abnormalities.


Minimal catabolism of "native" 125I-albumin and 131-I-gamma-globulin by polymorphonuclear leucocytes.


Naturally occurring rabbit antibodies against the tryptic 3-5S and 5S fragments of rabbit IgG--II.


A new type of human gamma heavy chain disease protein: immunochemical and physical characteristics.


Leukocytic function in hypogammaglobulinemia. The phagocytic, bactericidal, and metabolic capabilities of circulating blood leukocytes from three adults (two males, one female) with hypogammaglobulinemia and recurrent pneumonia, chronic sinusitis, and intestinal giardiasis were studied. These functions were found to be normal when leukocytes from the patients were incubated in media containing normal human serum. Phagocytosis of Staphylococcus albus and polystyrene balls by both patient and normal leukocytes was diminished when the cells were incubated in hypogammaglobulinemic plasma. A similar defect in opsonization by patient plasma was also noted for pneumococci, Escherichia coli and variably with Staphylococcus aureus. Both patient and normal sera had equivalent levels of heat-labile S. albus opsonins; normal serum, however, contained heat-stable S. albus-specific absorbable opsonins in significantly greater quantities to account for its superior opsonic capacity. The addition of commercial gamma globulin or purified IgG to hypogammaglobulinemic sera restored full S. albus opsonic activity. The relevancy of these observations to the impaired host defenses in these patients will be discussed.


Immunologic responses of graft recipients to antilymphocyte globulin: effect of prior treatment with aggregate-free gamma globulin. The immunologic response of graft recipients to antilymphocyte globulin has been studied. The clearance from the serum of (125)I-labeled antilymphocyte globulin was studied in 15 graft recipients previously treated with antilymphocyte globulin and in 4 control patients not previously treated with antilymphocyte globulin. The mean serum half-life of antilymphocyte globulin was 7.2 days in control patients, 3.8 days in 13 renal graft recipients, and 22 hr in 2 heart graft recipients. All but one of the antilymphocyte globulin-treated patients had rapid clearance. Patients treated with equine antilymphocyte globulin had rapid clearance of rabbit and goat antilymphocyte globulin as well as horse antilymphocyte globulin. All patients with rapid clearance of antilymphocyte globulin had circulating antibodies to xenogeneic gamma globulin. Two patients with rapid clearance of antilymphocyte globulin had circulating complexes of antilymphocyte globulin. Five renal graft recipients were treated with aggregate-free equine gamma globulin before antilymphocyte globulin therapy in an attempt to induce tolerance to xenogeneic gamma globulin. In these five patients neither rapid clearance of antilymphocyte globulin nor significant titers of circulating antibody to xenogeneic gamma globulin developed. The induction of tolerance to xenogenic gamma globulin may benefit patients treated with antilymphocyte globulin.


Ultrastructural evidence for the stimulation of nuclear ribonucleic acid synthesis by oestradiol-17 beta in the vaginal epithelium of the ovariectomized mouse.


Factor V anticoagulants: clinical, biochemical, and immunological observations. A patient who had received multiple transfusions for complications of acute hemorrhagic pancreatitis developed a potent factor V anticoagulant with bleeding due to defective hemostasis. Despite its potency, the anticoagulant disappeared within 15 days of its first manifestation. A second patient with adenocarcinoma of the colon developed an anticoagulant to factor V postoperatively after a single blood transfusion. The anticoagulants appeared to react stoichiometrically with factor V in normal plasma in vitro. They had the physicochemical properties of immunoglobulins, and their activity was neutralized by antihuman immunoglobulin antiserum. One anticoagulant appeared to be slightly more active against homologous than against autologous factor V, but it also inhibited heterologous factor V. Both anticoagulants progressively inactivated intrinsic prothrombin activator formed from normal reagents in the incubation mixture of the thromboplastin generation test, thus confirming that factor V is required for the effective action of the intrinsic prothrombin activator. Since the anticoagulants were immunoglobulins whose activity was consumed in their reaction with factor V, consumption of anticoagulant activity was used to detect factor V antigenic material in test materials. Human serum without factor V clotting activity was found to consume anticoagulant activity, i.e., to contain inactive factor V antigenic material. Plasma from two patients with hereditary factor V deficiency (parahemophilia) failed to consume significant anticoagulant activity. Thus, the lack of factor V activity in these patients represents a deficiency of factor V molecules rather than the synthesis of a defective molecule with impaired clotting activity.


The effect in vitro of thyroxine, glucagon, thyrotrophin and antithyroid drugs on 'usual' and 'atypical' human plasma cholinesterase.


The effect of fixation on the staining of the bacterial cross cell wall.


Electron histochemistry of normal and dystrophic muscle.


Environmental pollution. Nuisance, menace or disaster?


On the paw oedema resulting from subcutaneous injection of histamine liberators in the rat.


Anti-pollution measures: the impossible dream. 1.


Synchronisation of oestrus in Ayrshire heifers by the use of progestinated intra-vaginal pessaries.


A comparison of the fine structure of Micrococcus diversus, Neisseria catarrhalis and Neisseria sicca.


Effects of inspiration, expiration, and apnea upon pacemaking and block in atrial fibrillation.


His bundle recordings in patients with reciprocating tachycardias and Wolff-Parkinson-White syndrome.


His bundle recordings in bilateral bundle-branch block combined with Wolff-Parkinson-White Syndrome. Antegrade type II (Mobitz) block and 1:1 retrograde conduction through the anomalous bundle.


Usefulness of gram stain and routine and quantitative culture of sputum in patients with and without acute respiratory infection.


Nitro-olefins, combustion products of hydrocarbons. 3. 3-Nitro-2-methyl-2-butene, a combustion product of 2-methyl-2-butene.


Seroepidemiological studies on nasopharyngeal carcinoma by fluorescent antibody techniques with cultured Burkitt lymphoma cell.


Selective removal of ribonucleic acid responsible for hyperbasophilia in rat liver parenchyma during azo dye carcinogenesis.


Histochemical and histophysical investigations on the acetylation blockade of carboxylic groups of polysaccharides.


Preservation of immunofluorescence.

Preservation of immunofluorescence.


Birefringence of peroxidase and azo dye stains.


The effect of immunosuppressive therapy on serum factors involved in resistance to infection in the rat.


Clinicopathological study of nephrotic syndrome in childhood.


Unilateral pulmonary oedema after pleural aspiration.


Latex agglutination test for invasive amoebiasis.


Pyrexia in renal carcinoma.

Pyrexia in renal carcinoma.


Ketamine as an induction agent in anaesthetics.


Isocyanates in industry.

Isocyanates in industry.


Management of haemophilic haemarthrosis.


Consultant training.

Consultant training.


Psychological disturbance and oral contraceptives.


Routine operative cholangiography.

Routine operative cholangiography.


Beta-receptor antagonists.

Beta-receptor antagonists.


Mental retardation: risks of recurrence.


Lithium in pregnancy.

Lithium in pregnancy.


L-tryptophan versus E.C.T.

L-tryptophan versus E.C.T.


Bone pain from tumours.

Bone pain from tumours.


L-tryptophan verses E.C.T.

L-tryptophan verses E.C.T.


Treatment of phobias.

Treatment of phobias.


Tumor immunity in patients with Burkitt lymphoma.


The recurrent laryngeal nerves at thyroidectomy.


Incontinent nostalgia induced by L-dopa.


L-dopa with MK 485 for depression.

L-dopa with MK 485 for depression.


Combined treatment of Parkinson's disease with amantadine and L-dopa.


Echoviruses and carditis.

Echoviruses and carditis.


Extrafaucial diphtheria.

Extrafaucial diphtheria.


Plasma-insulin in diabetes.

Plasma-insulin in diabetes.


Fetal audiometry.

Fetal audiometry.


Psychiatric units in general hospitals.

Psychiatric units in general hospitals.


Use of thymine to increase the yield of mitoses in lymphocyte culture.


Thrombic enzyme from Crotalus adamanteus.


Gilbert syndrome and factor-VII deficiency.


Doctors' pay.

Doctors' pay.


Doctor's pay.

Doctor's pay.


Thyroid function in the preterm fetus.

Thyroid function in the preterm fetus.


Influence of spironolactone and other steroids on the enzymatic decay and anticoagulant activity of bishydroxycoumarin.


Thromboplastin as a reagent.

Thromboplastin as a reagent.


Isoagglutinin and immunoglobulin levels in maternal and cord sera.


Immunogenicity and specificity of collagen. X. Investigations on collagen determinants by inhibition experiments with peptides obtained after multiple degradation.


Thyroid function in sibships in endemic goiter region.


Accumulation of axoplasmic organelles in swollen nerve fibers.


The role of delayed hypersensitivity in immunological processes and its relationship to aphthous stomatitis.


Functional heterogeneity of virions in human adenovirus types 2 and 12. Purified preparations of adenovirus types 2 and 12 were used to infect KB cells at different input multiplicities. The resulting infected cultures were scored for inclusion body formation, production of infectious centers, and cloning efficiency. Both preparations were found to contain some defective particles capable of preventing a cell from cloning but unable to induce inclusion bodies or form plaques. The proportion of such defective particles in adenovirus 12 was about 10 times that in adenovirus 2. At high input multiplicities, the percentage of cells displaying an inclusion body was less than that predicted by the Poisson distribution and reached a maximum of 40 to 60% for adenovirus 2 and 12 to 15% for adenovirus 12. This reduction may be due to interference by large numbers of non-plaque-producing particles infecting each cell. The per cent of cells forming infectious centers was substantially greater for adenovirus 2 than for adenovirus 12 when compared at the same input plaque-forming units, reaching a maximum of 35 to 73% for adenovirus 2 and 5 to 10% for adenovirus 12. The low value for adenovirus 12 may be a result of the same interference phenomenon.


Host-cell lysosomal response to two strains of herpes simplex virus. A correlation has been made between the host lysosomal responses to and release of infectious virus from HEp-2 cells infected with two strains of herpes simplex virus (HSV). Supravital staining with acridine orange was used for morphological studies of macroplaque and microplaque HSV-infected cells. With the progression of infection, cells infected with either microplaque HSV or macroplaque HSV were observed to undergo different lysosomal and cytopathic changes, which could be correlated with increased accumulation of acid phosphatase and infectious virus in the extracellular fluid.


Delay of mengovirus-induced cytopathology in mitotic L-cells. The time course and extent of mengovirus production were the same in metaphase-arrested and interphase L-cells, yet the expression of cytopathology was delayed several hours in metaphase cells.


Characteristics of a virus isolated from a feline fibrosarcoma. A virus was isolated from a radioresistant feline fibrosarcoma. It induced multi-nucleated giant-cell formation and lysis in a cell line derived from a canine fibro-sarcoma, which was used to characterize the virus. End-point titrations in these cells required 28 days. The virus was sensitive to ether and heat and was destroyed at pH 3. Replication was not inhibited by 5-bromodeoxyuridine. Electron microscopy revealed assembly by a budding process from the plasma membrane of infected cells. The average diameter of the virion was 106 nm. Intracisternal particles with an average diameter of 45 nm were present within infected cells. In two instances secondary monolayers of feline renal cells underwent morphological transformation after inoculation of the virus. The two strains of transformed cells are now in continuous culture and do not yield infectious virus.


Characterization of Nodamura virus, an arthropod transmissible picornavirus.


Electron microscopic observations of Visna virus-infected cell cultures.


A possible paralysis virus of termites.

A possible paralysis virus of termites.


Structural features of vaccinia virus revealed by negative staining, sectioning, and freeze-etching.


Isopycnic zonal centrifugation and characterization of the mouse mammary tumor virus (MTV) in different gradient solutions.


Morphology of endocrine cells in the islet tissue of the cod Gadus callarias.


Effects of continuous daily administration of 0.5 mg of chlormadinone acetate on the plasma levels of progesterone and on the urinary excretion of luteinizing hormone and total oestrogens.


Effects of combined and low-dose gestagen oral contraceptives on plasma lipids; including individual phospholipids.


A pedigree demonstrating the transmission of a Gm2,8,21 phenogroup.


Studies on African Pygmies. IV. A comparative study of the HL-A polymorphism in the Babinga Pygmies and other African and Caucasian populations.


An analytical method for polynuclear aromatic compounds in coke oven effluents by combined use of gas chromatography and ultraviolet absorption spectrometry.


Antithyroid effects of lithium.

Antithyroid effects of lithium. Lithium has been reported to be goitrogenic when used for the treatment of manic-depressive psychosis. To investigate the effects of lithium on iodine metabolism, male Sprague-Dawley rats were placed on a low iodine (LID) or normal iodine diet (NID) containing enough Li(2)CO(3) to give serum lithium levels of 0.23-0.86 mEq/liter (human therapeutic range is 0.6-1.6 mEq/liter). The following effects were noted with lithium treatment: (a) thyroid weight increased concomitant with a slowing of thyroidal iodine release; (b) the ability to concentrate iodide was increased only after goiters were established; (c) on the LID, (131)I uptake was elevated throughout all phases of treatment, even when the release rate was normal; (d) iodine organification was unaffected but the proportion of (131)I present as iodothyronines was decreased; (e) the thyroidal (127)I content was increased; (f) despite these changes, the serum PBI remained normal as did the thyroxine turnover rate; and (g) thyrotropin (TSH) levels in serum were the same as controls except for a slight elevation early in the course of treatment; TSH levels did not correlate with goitrogenesis. When LiCl was injected in large doses into intact rats (giving serum lithium levels of 3.08-3.89 mEq/liter), the iodide concentrating mechanism, (131)I uptake, and (131)I release rates were depressed. Similar experiments in hypophysectomized rats receiving TSH demonstrated these to be local antithyroid effects not mediated through the pituitary. The discrepancy between acute and chronic responses to lithium, and the dissociation between the inhibition of iodine release and stimulatory effects is discussed.


A case of ventricular return extrasystoles with two consecutive re-entry sweeps to the atrium.


American trypanosomiasis (Chagas' disease) in Hylobates pileatus.


Proteolytic degradation of exocrine and serum immunoglobulins. The susceptibility of exocrine and serum immunoglobulins and antibodies to proteolytic degradation was assessed. Colostral and duodenal fluid exocrine 11S IgA, monomeric serum IgA, and IgG were digested with trypsin, chymotrypsin, or duodenal fluid. Exocrine IgA was more resistant to digestion than were the serum immunoglobulins. Under conditions of the experiments, most of colostral IgA retained its 11S quaternary structure, including the secretory piece; the portion degraded was reduced almost entirely to peptides. The superior resistance of exocrine IgA was also demonstrated by digestion of serum IgG and nasal exocrine IgA diphtheria antitoxins with trypsin or duodenal fluid. Selective precipitation of trypsin-digested antitoxins with antibodies to heavy chains, light chains, or secretory piece revealed that the differences in susceptibility to digestion were due to differences in lability of the Fc portions of the IgA and IgG antibody molecules. The Fc portions of IgG antibody molecules were degraded or cleaved from the Fab units of the molecules, whereas the Fc-like portions of IgA antibody molecules remained associated with their Fab-like units and the secretory piece. On the other hand, trypsin treatment did not affect the antigen binding ability of the Fab parts of either the exocrine IgA or IgG antibodies. The Fc-like portions of exocrine IgA may be protected from tryptic degradation by the quaternary structure of the 11S molecules, which includes a dimer of 7S IgA subunits and the secretory piece.


Density gradient electrophoresis.

Density gradient electrophoresis.


Thyroid function in domestic animals.

Thyroid function in domestic animals.


Rotationally stabilized electrophoresis.


I. Isolation and measurement of phytanic acid and related isoprenoid compounds by gas chromatography.


Air pollution: Muskie throws down the gauntlet.


Pancreatic malignancy in children.

Pancreatic malignancy in children.


Failure of cytotoxic drugs to suppress immune responses of patients with rheumatoid arthritis.


Procainamide-induced systemic lupus erythematosus.


Immunological surveillance.

Immunological surveillance.


Skin plasty in the surgical treatment of congenital elephantiasis in children combined with congenital constriction in the extremities.


On the question of regeneration of articular cartilage in case of damage or in arthroplasty.


New method reconstruction of urinary sphincter in epispadias. A preliminary report.


Mechanism of the origin of nose deformation in patients with inborn cleft of upper lip.


Development of sinus maxillaris in children with complete unilateral clefts. (Age class 4-7 years).


New method of reconstruction of auricle with figure graft from healthy ear.


Application of preserved heteroperitoneum for plastic operation of postoperational ventral hernia.


The caloric cost of weight gain after burns-the importance of M2 mixture in treatment.


Two types of chromaffin cells in the adrenals of the bullfrog, Rana catesbiana. A comparative study.


Procainamide induced lupus diathesis.

Procainamide induced lupus diathesis.


Acridine orange microfluorometry of DNA of Ehrlich ascites tumour cells and L-cells and its comparison with chromosome numbers.


Secondary fluorescence of some cell structures.


An extension of the nomenclature for immunoglobulins.


The use of gamma globulin as prophylaxis against infectious hepatitis in industry.


The effect of serum fractions on in vitro colloidal gold phagocytosis.


Hemagglutination technique with erythrocyte coated with specific antibody for detection of Australia antigen.


Comparative study on skin-necrotizing effect of scirpene metabolites of Fusaria.


A staining rack for radial immunodiffusion plates.


Contraceptive treatment with low doses of gestagens.


Arthralgia-purpura-weakness-cryoglobulinemia.


The chronic circulatory failure and the activity of the thyroid gland.


Stimulation of chicken lymphocytes in vitro by anti-immunoglobulin sera.


Precipitin reactions in normal chicken sera.


Increasing aortic permeability by atherogenic diet.


A quantitativ electron histochemical estimation of ruthenium red binding to heparin in mast cell granules.


The staining of elastic fibres with direct blue 152. A general hypothesis for the staining of elastic fibres.


On the specifieity of histochemically demonstrable bile canalicular phosphatase activities.


Indigogenic methods for glycosidases. I. An improved method for beta-D-glucosidase and its application to localization studies on intestinal and renal enzymes.


On the specificity of staining by Alcian blue in the study of human, foetal adenohypophysis.


An experimental silver study of the ascending projections of the central gray substance and adjacent tegmentum in the rat with observations in the cat.


Retrograde atrophy of axons of the medial lemniscus of the cat.


The anticoagulant malingerer. Psychiatric studies of three patients.


Screening for heterozygous alpha1-antitrypsin deficiency. II. Effect of other serum protein abnormalities.


Cryoglobulinemia and disease.

Cryoglobulinemia and disease.


The bacteriology of cervical mucus of ewes at oestrus following treatment with fluoro-progestagen impregnated intravaginal sponges.


Pseudoelastic nature of pterygium.

Pseudoelastic nature of pterygium.


Study of live typhoid vaccine in chimpanzees. Streptomycin-dependent Salmonella typhi containing O and H antigens was administered as a live oral antityphoid vaccine to chimpanzees. Five animals served as controls; 5 others received the vaccine 4 times at 3-day intervals; 4 further animals were given 4 doses of vaccine at 3-day intervals together with streptomycin; and 1 animal received the 4 doses of vaccine and a daily dose of streptomycin. The individual vaccine doses varied between 36x10(9) and 82x10(9) organisms, totalling about 258x10(9)Salm. typhi per animal. The chimpanzees were challenged with 26x10(9) cells of the virulent Salm. typhi Ty2 strain 10 days after immunization and followed up bacteriologically, serologically and clinically. It was observed that after this very heavy challenge the immunized animals that had received streptomycin with the vaccine were protected to some degree against the infection and showed fewer symptoms. The animal that received vaccine and streptomycin daily did not develop the disease.The authors point out that, while the strain used may have potential usefulness for the protection of man, further studies are needed to confirm the innocuity of the vaccine, to reduce the strain's reversion to streptomycin-independence, and to determine the relative effectiveness of different immunization dosages and schedules.


Olivary projections to the cerebellar nuclei in the cat.


Spinal projections to the cerebellar nuclei in the cat.


Axoplasmic transport of acetylcholinesterase and choline acetyltransferase in the vagus and hypoglossal nerve of the rabbit.


Plasma levels of growth hormone, insulin and plasma protein-bound iodine in finishing cattle.


Serum immunoglobulins in the differential diagnosis between intrahepatic viral jaundice and extrahepatic obstructive jaundice.


Modern educational aids for simplified explanations of handwriting comparisons.


Immunologic response of young patients with asthma and-or recurrent respiratory infections to aerosol influenza immunization.


Experimental pyelonephritis. A light and electron microscopic study of the periodic acid-Schiff positive interstitial cell.


Induction of hypotension in rhesus monkeys and rabbits by intravenous thrombin infusion.


Mutants of Neurospora deficient in aryl sulfatase.


Histochemical studies of the hepatic monoamine oxidase activity in rats treated with carbon tetrachloride.


Immunohistological studies on surgically bursectomized chickens.


Effect of hormone administration on the hypothalamic neurosecretory system of rats after pituitary stalk section.


Thyroid function tests: the chemical thyroid profile.


Laboratory findings in rheumatoid arthritis.


The comparative biochemistry of collagen: the structure of rabbit skin colllagen and its relevance to immunochemical studies of collagen.


The accumulation of cerebroside sulfates by fibroblasts in culture from patients with late infantile metachromatic leukocystrophy.


The nature of the striae of Retzius as seen with the optical microscope.


Changes in the serum proteins pattern in adults following electric burns.


Factors influencing cure in the radiotherapy of post cricoid carcinoma.


Organization of spinal motoneuron dendrites in bundles.


Postnatal changes in the concentration and distribution of cholinesterase in the cerebellar cortex of rats.


Regional distribution of isozymes of D-amino-acid oxidase and acetylesterase in developing primate brain.


Long term effect of medroxyprogesterone acetate in human ovarian morphophysiology and sperm transport.


The sperm- and seminal plasma-specific antigens of human semen.


Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness.


Genetic control of the specificity of anti-DNP antibodies. I. Differences in the specificity of anti-DNP antibody produced by mammalian species.


Genetic control of the specificity of anti-DNP antibodies. II. Differences in the specificity of anti-DNP antibody produced by several inbred strains of mice.


Interrelationships of tolerance and immunity. I. Induction of immunologic tolerance in adult mice to bovine gamma globulin purified in vivo.


Quantitative and qualitative studies of antibody to streptococcal M-protein.


Synthesis of the ninth component of complement by a clonal strain of rat hepatoma cells.


Immunosuppressive effect of serum from CBA mice made tolerant by the subernatant from ultracentrifuged bovine gamma globulin.


Treatment of premature cardiac contractions.


Transvesical prostatectomy; a nursing care study.


Plasma protein alterations accompanying cardiac and general surgical procedures.


Factors regulating the immune response. Report of a WHO scientific group.


Serum thyroxine in the early phase of subacute thyroiditis.


Death following a test injection of dihydrostreptomycin.


Nephrotoxicity due to cephaloridine: a light- and electron-microscopic study in rabbits.


Causes and conditions for the creation of nucleolar morphological changes with adenosine.


Comparison of swallow and chick embryos with regard to the progress of shoulder and hip joint differentiation.


Developmental stages of the prenatal spinal cord in man.


Progress in blood transfusion and immuno-haematology.


Structure of the anterior nucleus in the hypothalamus of the guinea-pig (Cavia aperea f. porcellus L.).


Overall staining of connective tissue and the muscular layer of vessels.


Various methods of staining tissue cultures in electron microscopy.


Immunoglobulin synthesis by blood lymphocytes--method of quantitation and the effect of phytohemagglutinin.


Intractable pain.

Intractable pain.


Diagnostic import of virus-like particles in the glomerular endothelium of patients with systemic lupus erythematosus.


Healthy IgE-deficient person.

Healthy IgE-deficient person.


Thyrotoxicosis. 2. Treatment.

Thyrotoxicosis. 2. Treatment.


A special-purpose analog computer for vectorcardiography.


Serum proteins in mentally retarded patients.


The use of performic acid oxidation to facilitate differential staining of epoxy-embedded adenohypophysis.


Metabolism, distribution and excretion of the thiophthalane lu 5-003, a bicyclic thymoleptic.


A study of the molecular types of immunoglobulin. I. Antibody response of rabbits to immunization with Salmonella typhosa antigens.


A study of the molecular types of immunoglobulin. II. Mouse protection study of Vi antibody against typhoid infection.


Immunofluorescent detection of foot-and-mouth disease virus in the esophageal-pharyngeal fluids of inoculated cattle.


Immunochemical quantitation of ovine immunoglobulins.


Electron microscopy of vascular barrier in thymus, tonsil, and lymph node of beagle pups.


Cytochemical approach to leukocytes, normal and leukemic.


Thermal analysis of polyanion metachromasy: effect of temperature on metachromatic solutions of nucleic acids and acid mucopolysaccharides.


Thermal analysis of polyanion metachromasy: temperature effects on stained cells, tissues and models.


Histochemical demonstration of sulfated mucosubstances and cationic proteins in human granulocytes and platelets.


Visualization of peroxisomes (microbodies) and mitochondria with diaminobenzidine.


Further observations on the peroxidatic activities of microbodies (Peroxisomes).


Comparison of bethanidine, alpha-methyldopa, and reserpine in essential hypertension.


Surgical correction of Ebstein's anomaly.


Possible role of Mycoplasma fermentans in pathogenesis of rheumatoid arthritis.


An encephalitogenic virus (Langat) in mice. Isolation and persistence in cultures of brains after intraperitoneal infection with the virus.


Gastric emptying of starch meals in the newborn.


Septicaemia and pulmonary embolism complicating use of arteriovenous fistula in maintenance haemodialysis.


Different Australia-antigen determinants in acute viral hepatitis.


Decline in blood activity of 125-I-fibrinogen in venous thrombosis.


Thyroid involvement in juvenile amaurotic family idiocy (Batten's disease).


Screening for hypertension.

Screening for hypertension.


Burkitt lymphoma and malaria.

Burkitt lymphoma and malaria.


Subphrenic abscess: a changing pattern.

Subphrenic abscess: a changing pattern.


Classification of infantile malnutrition.


Atlantic trends.

Atlantic trends.


Aetiology of rheumatoid arthritis.

Aetiology of rheumatoid arthritis.


The red tide.

The red tide.


A study of consultants.

A study of consultants.


Successful new medical school.

Successful new medical school.


Architects look at health and welfare.

Architects look at health and welfare.


Dip inoculation media.

Dip inoculation media.


Syndrome of the sea-blue histiocyte.

Syndrome of the sea-blue histiocyte.


Familial metaphyseal dysplasia.

Familial metaphyseal dysplasia.


Ketamine.

Ketamine.


Milk-bottle problem.

Milk-bottle problem.


Au-antigen particles.

Au-antigen particles.


Agent transmissible from Crohn's disease tissue.


Effect of L-dopa on seborrhoea of Parkinsonism.


Effect of L-dopa on seborrhea of Parkinsonism.


Carpometacarpal osteoarthritis of the thumb.


Transfusion malaria.

Transfusion malaria.


Homeless men.

Homeless men.


Plasma-calcitonin in man.

Plasma-calcitonin in man.


Cerebral atrophy in drug addicts.

Cerebral atrophy in drug addicts.


Portable heparin injector.

Portable heparin injector.


Rosette tests in autoimmune haemolytic anaemias.


Sex ratio in phenylketonuria.

Sex ratio in phenylketonuria.


Is lyonisation total in man?

Is lyonisation total in man?


Gene-frequencies in Jews.

Gene-frequencies in Jews.


Lithium depletion and atherosclerotic heart-disease.


Convulsion during lithium therapy.

Convulsion during lithium therapy.


Eliminating red blood-cells from amniotic-fluid samples.


Intensive-coronary-care units.

Intensive-coronary-care units.


Relative hypoglycaemia?

Relative hypoglycaemia?


Exercise-sandals and metatarsalgia.

Exercise-sandals and metatarsalgia.


Emanuel Miller. M.A. Cantab., F.R.C.P., D.P.M.


The rational use of anticoagulants.

The rational use of anticoagulants.


Prenatal assessment of blood group antibodies against "public" antigens. An example of anti-Ve (Vel) in pregnancy.


Modified surface staining of cardiac valve leaflets.


Increased opsonic capacity of serum in chronic heroin addiction.


Apathetic thyrotoxicosis: A distinctive clinical and laboratory entity.


Prolonged immunological disorder terminating in hematological malignancy: A human analogue of animal disease?


Occupational exposure to aldrin: clinical and laboratory findings.


Occupational exposure to lindane: clinical and laboratory findings.


Spermiogenesis in an iceryine coccid, Steatococcus tuberculatus Morrison. An electron microscopic study.


The response in toxic diffuse goitre to a short course of antithyroid therapy.


Stimulation of cell growth in vitro by serum with and without growth factor. Relation to contact inhibition and viral transformation.


Localization of mouse satellite DNA in constitutive heterochromatin.


Nucleolar segregation by adenosine 3'-deoxyriboside (cordycepin) in root-tip cells of Allium cepa.


The "symbodies". A factor in the pathogenesis of ulcerative colitis?


First case of a nonallelic interaction product as a species-specific red cell antigen.


The unconscious fantasy of infanticide manifested in resistance.


The terms "mother" and "father" as a defense against incest.


Apparent movement detection in the pigeon. Pigeons were trained to discriminate between the presence and absence of apparent movement in visual displays. Generalization gradients obtained on the dimension of speed indicated a broad range of movement detection. Extremely accurate discrimination performance on displays varying in direction of movement suggested formation of a "movement concept".


Transient visual obscurations in chronic rheumatic heart-disease.


Prophylactic lithium: double blind discontinuation in manic-depressive and recurrent-depressive disorders.


Sarcoidosis, thyroiditis, and Addison's disease.


Effect of oral contraceptives on lipoprotein lipase activity and platelet stickiness.


Long-acting thyroid stimulator in Graves' disease.


Complication of bone-marrow transplantation. Graft-versus-host disease resulting from chronic-myelogenous-leukaemia leucocyte transfusions.


Protein synthesis by the liver after transplantation.


More about Australia antigen and hepatitis.


L.A.T.S.

L.A.T.S.


Control of lymphocyte level in the blood.


Vibration syndrome.

Vibration syndrome.


Light on obscurations.

Light on obscurations.


Fluorides and human health.

Fluorides and human health.


After all that.

After all that.


Malabsorption in the tropics.

Malabsorption in the tropics.


ABC of endocrinology. 8. Insulin and glucose homoeostasis.


Sterilisation of women.

Sterilisation of women.


An immunological approach to ageing.

An immunological approach to ageing.


Criteria of rheumatic fever.

Criteria of rheumatic fever.


Medical care in the United States.

Medical care in the United States.


Treatment of nocardiosis.

Treatment of nocardiosis.


And histoplasmosis.

And histoplasmosis.


Perforated Crohn's.

Perforated Crohn's.


Venereal disease.

Venereal disease.


Multiple tumours.

Multiple tumours.


Plasma-catecholamine estimations.

Plasma-catecholamine estimations.


Suicide prevention.

Suicide prevention.


Serotonin levels in infant hypothyroidism.


Renpenning's syndrome--X-linked mental retardation.


Pulmonary oedema after pleural aspiration.


Iatrogenic cystinuria.

Iatrogenic cystinuria.


Mycoplasma in urogenital tract.

Mycoplasma in urogenital tract.


Alcoholism and colour-vision: are there familial links?


Rapid detection of Australia antigen by cross-over electrophoresis.


Diabetes and migraine.

Diabetes and migraine.


Detection of Gaucher's disease and its carrier state from fibroblast cultures.


Prenatal detection of Pompe's disease.

Prenatal detection of Pompe's disease.


Increased IgA in schizophrenic patients.


Severe childhood hypertension following central-nervous-system infection.


Gonadotrophins and testosterone in the XYY syndrome.


Free-cyanide levels in tropical ataxic neuropathy.


Digestion in the newborn.

Digestion in the newborn.


Retention fee demand by G.M.C.

Retention fee demand by G.M.C.


Ronald Henry Gorrill, M.D. Lond., F.R.C. Path.


Prednisolone treatment of lupus nephritis: Effect of high doses on course of disease, renal function, histological lesions, and immunological reactions.


Renin inactivation by human plasma.

Renin inactivation by human plasma.


Malum perforans in a young girl with spina bifida.


Mitochondrial RNA from cultured animal cells. Distinctive high-molecular-weight and 4 s species.


Attachment of cells cultured in vitro to enamel.


Epidemiological approach to assessment of health.


Oral contraceptives and low antithrombin-3 concentration.


The toluidine blue test in lesions of the oral cavity.


Hepatitis-associated (Au-SH) antigen determination in 10,000 patients in a Copenhagen general hospital.


Australia antigen in west of Scotland and north of England.


Clinical significance of renal haemodynamics in acute myocardial infarction.


Acute dilatation of colon in Crohn's disease.


Early post-concussional headache.

Early post-concussional headache.


Leucocyte glutaminase in familial protein intolerance.


Diabetes, diabetic angiopathy, and growth hormone.


Mobile coronary care.

Mobile coronary care.


Simple indwelling cannula for repeated peritoneal dialysis.


Removal of swallowed neonatal endotracheal tube.


Glucagon in cardiac failure.

Glucagon in cardiac failure.


Homeless men.

Homeless men.


Cancer research campaign.

Cancer research campaign.


The carotid body.

The carotid body.


Rh immunisation and abortion.

Rh immunisation and abortion.


Retirement of Prof. Ritchie Russell.

Retirement of Prof. Ritchie Russell.


Hepatitis-associated antigen. To test or not to test?


De malariae morbo. Obiter dicta.

De malariae morbo. Obiter dicta.


Cheese and 'parnate'.

Cheese and 'parnate'.


An inquest quashed.

An inquest quashed.


Mistaken identity.

Mistaken identity.


Ototoxic antibiotics.

Ototoxic antibiotics.


The threat of Rh immunisation from abortion.


Specialisation within pathology.

Specialisation within pathology.


Work of the anaesthetist.

Work of the anaesthetist.


Ketamine.

Ketamine.


Modification of donor lymphocytes for transplantation in lymphopenic immunological deficiency.


Use of antacids in patients on chronic dialysis.


Sex ratio in phenylketonuria.

Sex ratio in phenylketonuria.


Orange palms in Lancashire.

Orange palms in Lancashire.


Treatment of phobias.

Treatment of phobias.


Contamination of blood stored in plastic packs.


Virus-like particles in serum of an apparently healthy Au-SH-antigen-positive blood-donor.


Smoking habits and laboratory tests.

Smoking habits and laboratory tests.


Ampicillin rashes.

Ampicillin rashes.


Acetazolamide and renal stone formation.


Urinary oestrogen profiles and aetiology of breast cancer.


Triethylene tetramine.

Triethylene tetramine.


Effect of L-dopa on seborrhoea of parkinsonism.


Amantadine versus L-2 dopa and amatadine plus L-dopa.


Rattlesnike bite.

Rattlesnike bite.


Herpes encephalitis treated with idoxuridine.


Alan Henderson Hunt, D.M.,M.Ch. Oxon. F.R.C.S.


Characterization of cell types in the parenchyma of Schistosoma mansoni.


Treatment of acute myocardial infarction. 2. Ventricular ectopic arrhythmias.


Structure and evolution of immunoglobulins.


Purification and electron microscopy of sowthistle yellow vein virus.


Acylation and deacylation reactions catalyzed by kynurenine formamidase.


Immunochemical quantitation of acute phase reactive proteins in myocardial infarction.


Inflammatory bowel disease in a family. Observations related to pathogenesis.


Electron microscope observations on the chemical component of the sheath of the middle piece of atypical spermatozoa of the pond snail, Cipangopaludina malleata Reeve.


Electron microscope autoradiography with special reference to the problem of resolution.


The correlative light and electron microscopy of the islets of Langerhans in some lower vertebrates.


Electron microscope studies on the release of histamine from rat peritoneal mast cells.


Examination of histochemical techniques for demonstrating histamine in mast cells.


Transurethral resection.

Transurethral resection.


Less common types of arthritis.

Less common types of arthritis.


Cell types in the pituitary of the medaka, Oryzias latipes.


Biochemical differentiation of equine anemias.


Excretory micturition cystourethrography (EMCU) in the adult age group.


The stability of deviant behavior over time: a reassessment.


Decline of tissue noradrenaline under the influence of a mitotic inhibitor.