Effects of progesterone and related compounds on fertilization, transportation and development of rabbit eggs.


Effects of perchlorate and other anions on thyroxine metabolism in the rat.


Charge and size of the conversion products of serum beta-1C-globulin.


Value of isoniazid-thiacetazone combination in unsupervised ambulatory cases of pulmonary tuberculosis.


A comparative radiological study of costal cartilage calcification in rheumatoid arthritis and in osteoarthrosis.


Intracellular biosynthesis of rabbit antibody.


Localization and characteristics of hexose 6-phosphate dehydrogenase (glucose dehydrogenase).


The effect of antibody on the induction of tolerance to human gamma-globulin in ICR albino mice.


Effect of heterologous antibody on tolerance to bovine gamma-globulin in CBA mice.


Synthesis of immunoglobulins by human cell lines in tissue culture.


Antigenic structure of gamma-E-globulin and reaginic antibody.


Histochemical study of bone in hydrocortisone- and fluoride-treated rats.


Chromic chloride: a coupling reagent for passive hemagglutination reactions.


Hemolytic plaque formation by mouse spleen cells producing antibodies against rabbit immunoglobulin G.


The effects of methionine and ethionine on antibody formation in primates.


Binding of albumin to gamma-A-myeloma proteins and Waldenström macroglobulins by disulfide bonds.


Immunoglobulins after surgical bursectomy in chickens.


Serum autoantibodies in myasthenia gravis and thymoma: selective affinity for I-bands of striated muscle as a guide to identification of antigen(s).


Canine nonprecipitating and rabbit precipitating antisera against the dinitrophenyl group.


Adsorption of proteins by polystyrene particles. I. Molecular unfolding and acquired immunogenicity of IgG.


Study of autoimmune disease in New Zealand mice. II. Immunologic and parabiotic studies of NZB-NZW F1 hybrids.


Histochemical studies of the relationship of chromaffin cells and adrenergic nerve fibers to the cardiac ganglia of several species.


Some uses of fluorescence in prosthodontics.


Operating room forum: skin care before operation prevents infection after.


Dose-dependence of drug plasma level decline in dogs.


Postnecrotic cirrhosis and pneumococcal peritonitis.


Growth and growth hormone. II. A comparison of isolated growth-hormone deficiency and multiple pituitary-hormone deficiencies in 35 patients with idiopathic hypopituitary dwarfism.


Guinea pig complement: two active forms of first component. By solubility chromatography at pH 7.5 and low ionic strength, a partially purified preparation of the first component of guinea pig complement was separated into two fractions of different solubility under these conditions. On rechromatography, each fraction emerged in the same position as it had originally.


Cryotherapy of benign and neoplastic tumors of the prostate.


Identification of immunocompetent cells in tissue culture.


Riboflavin and mouse hepatic cell structure and function. I. Ultrastructural alterations in simple deficiency.


Radioactive phosphorus in normal and pathological prostate.


Sodium deprivation and renin secretion in unanesthetized dogs.


A simplified Mallory's phosphotungstic acid-hematoxylin stain.


Effects in long bones distal to an arteriovenous fistula elicited by oxytetracycline labelling.


A simplified toluidine blue stain for mast cells.


Ultrastructure of synovial membrane in human hemarthrosis.


Improved technique of gastric aspiration.


Lack of relation between plasma-growth-hormone levels and small decrements in blood-sugar.


Ampicillin in the treatment of Listeria monocytogenes meningitis.


Extreme leucocytosis in accidental electric shock.


Testing of anti-human lymphocyte sera in chimpanzees and lower primates.


Spiramycin the the prevention of postoperative staphylococcal infection.


Prostaglandin secretion by medullary carcinoma of the thyroid. A possible cause of the associated idarrhoea.


Lesions in the vasa recta in experimental analgesic nephropathy.


Device for single-handed opening and closing of an arm shunt in independent haemodialysis.


Inheritance of fibrin-stabilising-factor deficiency.


Flying sparks.

Flying sparks.


Prostaglandins.

Prostaglandins.


Gastroenteritis due to Escherichia coli.


Dangers of asbestos.

Dangers of asbestos.


Pityriasis rosea.

Pityriasis rosea.


Adipose tissue and insulin.

Adipose tissue and insulin.


Obstruction of cervical arteries.

Obstruction of cervical arteries.


Obstetrics and gynaecology.

Obstetrics and gynaecology.


Physical ill-treatment of children.

Physical ill-treatment of children.


Cigarette smoking, respiratory symptoms, and anti-smoking propaganda. An experiment.


Overvisiting of hospital patients.

Overvisiting of hospital patients.


The epileptic in the bath.

The epileptic in the bath.


The community-care unit.

The community-care unit.


Bedsores.

Bedsores.


Pain after head injury.

Pain after head injury.


Water and electrolytes in muscle.

Water and electrolytes in muscle.


Treatment of fractured clavicle.

Treatment of fractured clavicle.


Acute respiratory failure in asthma.

Acute respiratory failure in asthma.


Availability of bromethol.

Availability of bromethol.


Clofibrate in glaucoma.

Clofibrate in glaucoma.


Cephaloridine toxicity.

Cephaloridine toxicity.


A dermatological drug sheet.

A dermatological drug sheet.


Systemic infections in heroin addicts.

Systemic infections in heroin addicts.


Hyperosmolar non-ketotic coma.

Hyperosmolar non-ketotic coma.


Insulin response to glucagon.

Insulin response to glucagon.


Vitamin B 12 and fertility.

Vitamin B 12 and fertility.


Allwork SP: Fibrinolysis and bleeding in open-heart surgery.


Neuropathy in porphyria.

Neuropathy in porphyria.


Bleeding time after aspirin ingestion.

Bleeding time after aspirin ingestion.


Venous stasis and fibrinolysis.

Venous stasis and fibrinolysis.


Emptying the Kill kidney.

Emptying the Kill kidney.


Peritoneal dialysis in malaria.

Peritoneal dialysis in malaria.


Bacterial endocarditis.

Bacterial endocarditis.


Conjunctiva in vitamin B deficiency.

Conjunctiva in vitamin B deficiency.


Effects of beta-blockade on coronary flow.


Synchronising cell division before cytotoxic treatment.


Nephrotic syndrome after treatment with D-penicillamine.


Humoral factors in canine renal allograft rejection.


Pentagastrin snuff. A new means of stimulating gastric secretion.


Leucopenia and fever in the "Jarisch-Herxheimer" reaction of louse-borne relapsing fever.


Blocking and binding autoantibody to intrinsic factor.


Perforating injuries of the bowel complicating peritoneal catheter insertion.


Focal sensory-motor seizures of spinal origin.


Alteration of superficial bacterial flora in severely ill patients.


Does deconjugation of bilirubin glucuronide occur in obstructive jaundice?


Effect of ethanol on liver delta-aminolaevulinate synthetase in rats.


Genetic susceptibility and somatic mutation in the production of freckles, birthmarks and moles.


Episiotomy.

Episiotomy.


A cryoprecipitate pooling set.

A cryoprecipitate pooling set.


Malignant melanomas.

Malignant melanomas.


Neurological complications of carbon-monoxide poisoning.


Amoebiasis.

Amoebiasis.


Intramedullary neuromas and spinal cord regeneration.


Still Q fever.

Still Q fever.


Formulation and absorption of drugs.

Formulation and absorption of drugs.


Infective hepatitis.

Infective hepatitis.


Control of feedstuffs for laboratory animals.


Medical students and general practice.

Medical students and general practice.


Problems of compulsory emergency admissions.


Fallacies in medical education.

Fallacies in medical education.


Doctor as manager.

Doctor as manager.


A national chemical-pathology service?

A national chemical-pathology service?


The community-care unit.

The community-care unit.


A national chemical pathology service?

A national chemical pathology service?


Viability of frozen lymphocytes.

Viability of frozen lymphocytes.


Lymphocyte culture in agar.

Lymphocyte culture in agar.


Phytohaemagglutinin in aplastic anaemia.


Microangiopathic haemolytic anaemia.

Microangiopathic haemolytic anaemia.


Free fatty acids in diabetes.

Free fatty acids in diabetes.


Hyperosmolar non-ketotic coma.

Hyperosmolar non-ketotic coma.


Insulin response to glucagon.

Insulin response to glucagon.


Growth hormone in African pygmies.

Growth hormone in African pygmies.


Intrinsic factor theory of Castle.

Intrinsic factor theory of Castle.


Physiological tremor.

Physiological tremor.


A special fluoridated school milk?

A special fluoridated school milk?


Heart-block in myocardial infarction.

Heart-block in myocardial infarction.


Bacteriology in the surgery.

Bacteriology in the surgery.


Venous stasis and fibrinolysis.

Venous stasis and fibrinolysis.


Hyperblastic response to dilute P.H.A. in Down's syndrome.


Withdrawal fits.

Withdrawal fits.


Histamine and overdosage of methaqualone and diphenhydramine.


Hypothyroidism after sulfphonulurea.

Hypothyroidism after sulfphonulurea.


Teaching aids for the mentally retarded child.


Methotrexate in psoriasis.

Methotrexate in psoriasis.


Quantitative immunoglobulin assays in patients with lymphatic neoplasms.


Gustav Giemsa (1867-1948).

Gustav Giemsa (1867-1948).


The inner speech of psychotherapy.

The inner speech of psychotherapy.


Some aspects of the vascularization and chemical histology of the pineal gland in Gallus.


Isolation and properties of a specific bacterial ribonuclease inhibitor.


Improved impregnation of degenerating boutons in Nauta-Laidlaw preparations.


A method for selective staining of damaged yeast cells.


Separation of mast cells from the peritoneal fluid of the rat with a GE nucleopore filter.


Alterations in human serum beta-1C-gobulin (C'3) in renal transplantation.


Hypergammaglobulinemia in ferrets with lymphoproliferative lesions (Aleutian disease).


The effect of ethchlorvynol on the drug-metabolizing enzymes of rats and dogs.


Studies on the properties of a human fetal serum protein.


Complement and lysozyme requirements for spirochetolysis in guinea pig serum. During experiments on the immunological immobilization of treponemes, several cultured strains were lysed in the guinea pig serum used as a source of complement. In further studies employing Borrelia vincentii, lysis, observed by darkfield, appeared as swelling and some beading of the cells. Complete disruption eventuated. Untreated guinea pig serum was strongly lytic, whereas little or no lysis occurred in bentonite-adsorbed samples. Activity was restored to these samples by adding commercially obtained crystalline egg-white lysozyme. Serum samples which had been heated, absorbed with aggregates of human gamma-globulin, or treated with ethylenediaminetetraacetate to remove, or inactivate, complement also lost spirochetolytic activity.


Association of experimental chronic arthritis with the persistence of group A streptococcal cell walls in the articular tissue. A single injection of isolated fragments of group A streptococcal cell walls into the joints of rabbits stimulated an initial acute reaction which was followed by a prolonged inflammatory process. The chronic process was characterized by hyperplasia of the synovial cells, diffuse infiltration of the villi by macrophages, and focal collections of lymphocytes in the stroma of the villi. These histological changes were similar to those seen in the early stages of rheumatoid arthritis. Antibodies specific for the mucopeptide and group-specific C polysaccharide antigens of group A streptococcal cell walls were labeled with either fluorescein or (125)I, and were used to demonstrate antigen in the synovial tissues. The antigens persisted within macro-phages for at least 5 weeks. Their presence correlated with the evolution of the chronic inflammatory process.


Replacement of ascitic fluid or rabbit serum requirement of Treponema dentium by alpha-globulin.


Filament ultrastructure and organization in vertebrate smooth muscle. Contraction hypothesis based on localization of actin and myosin. Using a variety of preparative techniques for electron microscopy, we have obtained evidence for the disposition of actin and myosin in vertebrate smooth muscle. All longitudinal myofilaments seen in sections appear to be actin. Previous reports of two types of longitudinal filaments in sections are accounted for by technical factors, and by differentiated areas of opacity along individual filaments. Dense bodies with actin emerging from both ends have been identified in homogenates, and resemble Z discs from skeletal muscle (Huxley, 1963). In sections, short, dark-staining lateral filaments 15-25 A in diameter link adjacent actin filaments within dense bodies and in membrane dense pataches. They appear homologous with Z-disc filaments. Similar lateral filaments connect actin to plasma membrane. Dense bodies and dense patches, therefore, are attachment points and denote units analogous to sarcomeres. In glycerinated, methacrylate-embedded sections, lateral processes different in length and staining characteristics from lateral filaments in dense bodies exist at intervals along actin filaments. These processes are about 30 A wide and resemble heavy meromyosin from skeletal muscle. They also resemble heads of whole molecules of myosin in negatively stained material from gizzard homogenates. Intact single myosin molecules and dimers have been found, both free and attached to actin, even in media of very low ionic strength. Myosin can, therefore, exist in relatively disaggregated form. Models of the contraction mechanism of smooth muscle are proposed. The unique features are: (1) Myosin exists as small functional units. (2) Movement occurs by interdigitation and sliding of actin filaments.


The Kveim-Siltzbach test. Report of a new British antigen.


Influence of sex in immunoglobulin levels.


Influence of some immunological procedures on experimental atherosclerosis in rabbits.


Adsorption of globulin to the cuticle of larvae and adults of Trichinella spiralis.


Haemolytic complement level and ragocyte (R A cell) concentration in synovial fluid.


Carboxyhemoglobinemia in parking garage employees.


Studies on transmissible gastroenteritis of swine. 3. The effect of selective inhibitors of viral replication on a cytopathogenic virus from transmissible gastroenteritis. The effect on the plaque production of the Purdue strain of cytopathogenic virus from transmissible gastroenteritis of swine by 5-bromo-2'-deoxyuridine (BUDR), 5-iodo-2'-deoxyuridine (IUDR), actinomycin-D, puromycin, and amantadine-HCI (Symmetral) has been studied.Amantadine-HCI reduced the plaque-forming units of virus per ml by approximately 98%. Puromycin prevented almost all virus reproduction while actinomycin-D caused approximately a 22% reduction. Both IUDR and BUDR produced approximately a 20% increase in plaque-forming units of virus per ml. Swine testis cells stained with acridine orange early in the course of infection contained brick-red particles in the cytoplasm, indicative of a ribonucleic acid (RNA) type virus.


Practical applications for perceptual training.


The accuracy of fluorescence microscopy for the diagnosis of cancer.


Membrane immunofluorescence reactions of Burkitt lymphoma cells from biopsy specimens and tissue cultures.


The specificity of the staining of amyloid deposits with thioflavine T.


Discrepancies in analyses of deoxyribonucleic acid in rabbit spermatozoa, involving Feulgen staining (Feulgen-DNA) and ultraviolet light absorption (UV-DNA) measurements.


Cyanotic congenital heart disease: new trends in management of transposition of the great arteries.


Composite carcinoid tumor (argentaffinoma-adenocarcinoma) of the colon: report of 2 cases.


The cytologic diagnosis of lymphnode punctures.


Evidence for a "governor" on protein synthesis in animal cells: positive signals in serum.


A seminar on child care as a facet of community psychiatry.


Control of synthetic activity in differentiating cells.


Homoreactant: a new serum factor in "normal" rabbits.


Branching pattern of amacrine cell processes.


Catecholamines in the carotid body of the cat.


Microglobulin synthesized in cell culture of the lymph nodes and spleen of the rabbit.


Absence of allotype b4 in the heavy chains of rabbit gamma-G-immunoglobulin.


Acute febrile anaemia associated with Bartonella-like erythrocytic structures.


Factors influencing lysis of whole blood clots.


Serum proteins in liver disease.

Serum proteins in liver disease.


Morphological changes following ultraviolet microbeam irradiation of parts of nuclei of living cells.


Uptake of protein by mammalian cells: an underdeveloped area. The penetration of foreign proteins into mammalian cells can be measured and their functions explored. Although it is accepted on the basis of biological and morphological evidence that mammalian cells will take up macromolecules, little is known about the kinetics, the specificity, and the functions of this uptake. With labeled proteins used as models, it is found that the transport proceeds at very low rates, requires little energy, and is markedly enhanced by polybasic compounds. Molecular charge and size are important factors: cells clearly favor cationic macromolecules of large molecular weights. Neither factor, however, can fully account for the selectivity detected in the uptake of different proteins. Ingested albumin undergoes rapid and extensive degradation. This fact suggests that macromolecules have only a limited chance to express their biological activity in target cells, a finding that is relevant also to the role of foreign nucleic acids and the possibility of achieving genetic transformation in animal cells. There are concrete indications, however, that in spite of their short half-life, proteins can act as carriers, as precursors of active agents, and as regulators of metabolic functions in host cells. They may also be important in the control of growth and differentiation. These functions of exogenous proteins are still largely unexplored.


Two-stage procedure for the quantitative determination of autoprothrombin 3 concentration and some applications.


Does preoperative instruction make a difference?


Measuring the coagulability of fibrinogen in plasma by isotopic means. Method and principles of its use for in vivo studies.


Vital staining of the cornea and conjunctiva; with a mixture of fluorescein and rose bengal.


The distribution, structure, origin and nature of the dental cuticle of Gottlieb.


Perceptual inconstancy in early infantile autism. The syndrome of early infant autism and its variants including certain cases of childhood schizophrenia.


The physiological role of the lymphoid system. IV. The separation of gamma globulin into physiologically active components by cellulose phosphate chromatography.


The physiological role of the lymphoid system. V. The binding of autologous (erythrophilic) gamma globulin to human red blood cells.


The physiological role of the lymphoid system. VI. The stimulatory effect of leucophilic gamma globulin (leucokinin) on the phagocytic activity of human polymorphonuclear leucocyte.


Fluorescent probes for the study of the antibody-hapten reaction. II. Variation in te antibody combining site during the immune response.


Use of an immunoadsorbent for the isolation of anti-immunoglobulin antibodies.


Synthesis of serum albumin, embryo-specific alpha-globulin and conalbumin by the chick yolk sac.


Preparation of a glycopeptide from an immunoglobulin kappa polypeptide chain from the mouse.


The diagnosis of prostatic cancer: cytological and biochemical studies using the franzen biopsy needle.


An evaluation of routine cytological examination of the urine.


Structure of the rat testis after the administration of 2-thio-6-azathymine.


Chlorinated hydrocarbon pesticides in cosmetics.


Congenital indifference to pain. Report of a case.


Multiple myeloma and macroglobulinemia cases in Hawaii.


Evaluation of the short child.

Evaluation of the short child.


Thyroxine and pyridoxine interactions on cholesterol metabolism in the chick.


Interpolated extrasystoles.

Interpolated extrasystoles.


The structure of antibodies. The basic pattern of the principal class of molecules that neutralize antigens (foreign substances in the body) is four cross-linked chains. This pattern is modified so that antibodies can fit different antigens.


Scrapie in the rat: an electron-microscopic study. II. Glial inclusions.


Acid phosphatase and non-specific esterase in normal and reactive glia of human nervous tissue. A histochemical study.


Interview interaction behavior of nurses with task versus person orientation.


Electron microscopic study of an ectopic pinealoma.


Glutaraldehyde fixation in routine histopathology.


Acidophilic bodies. Their chemical and physical nature in patients with Bolivian hemorrhagic fever.


Canine histiocytic ulcerative colitis. A condition resembling Whipple's disease, colonic histiocytosis, and malakoplakia in man.


Rubella: a method for rapid diagnosis of a recent infection by demonstration of the IgM antibodies.


Stimulatory effect of polycyclic hydrocarbons and aromatic azo derivatives on the metabolism of 7,12-dimethylbenz(alpha)anthracene.


Myocardial cell and sarcomere lengths in the normal dog heart.


Hepatic synthesis and secretory release of plasma alpha-2 (acute phase)-globulin appearing in malignancy.


An automated method for the determination of serum organic iodine.


Desensitization in vitro--the specific inhibition, by antigen, of the passive transfer of delayed hypersensitivity by peritoneal exudate cells.


Evidence for the independence of human immunoglobulin class levels.


Interaction of IgG and its fragments with red cells.


Studies on the mechanism of immunoglobulin binding to red cells.


Macrophage-like properties of some guinea-pig transformed cells.


Antigen in tissues. IV. The effect of antibody on the retention and localization of antigen in rat lymph nodes.


Antibacterial activity of human prostatic fluid.


Heterogeneity of skin-sensitizing antibodies.


Disappearance of intradermally administered plasma immunoglobulins and skin-sensitizing antibodies.


Antibody response following immunotherapy in ragweed hay fever: Allpyral vs. whole ragweed extract.


Ascaris hypersensitivity in the rhesus monkey. I. A model for the study of immediate type thypersensitity in the primate.


Thyroxine secretion rate in the horse in various physiological states.


Student sets of color slides as an aid in teaching microscopic anatomy.


Measles immune globulin. Proposed standard dose given with liver attenuated measles virus vaccine.


Urban haze: the extent of automotive contribution. Observation of the correlation between nitrogen oxides and the extinction coefficient of atmospheric air suggests that the automobile exhaust aerosol (nonphotochemical) may be important to visibility in cities.


Perspective of human cell culture.

Perspective of human cell culture.


Fatal herpes simplex infection in the newborn. Caesarean section as a prophylactic measure.


Paraproteinaemia and unusual dys-gamma-globulinaemia in a case of Wiskott-Aldrich syndrome. An immunochemical study.


Survival times after treatment of pathologic fractures.


Validation of an indicator of mammalian retinal receptor response: recovery in the dark following exposure to a luminous stimulus.


A morphological comparison of Bittner and influenza viruses.


The mechanism of appearance of immunoglobulin A in nasal secretions in man. Experiments were done to investigate mechanisms of appearance of both 7 S and 11 S IgA in nasal secretions. Three IgA preparations, (a) 11 S IgA from nasal secretions, (b) 7 S IgA from homologous serum, and (c) 7 S IgA from autologous serum, were isolated, labeled, and injected intravenously into volunteers. The rate of disappearance from plasma and the extent and nature of their appearance in nasal secretions were examined in detail. After intravenous injection, 11 S IgA from nasal secretions disappeared rapidly from plasma. However, only negligible amounts of 11 S IgA were detected in nasal secretion, which suggested that rapid selective secretion of circulating 11 S IgA does not occur as a mechanism of IgA accumulation in nasal secretions. Both the homologous and autologous 7 S IgA preparations disappeared from plasma at a normal rate, and both appeared in nasal secretions unchanged in sedimentation behavior. The specific activity of IgA in nasal secretions, when related to the total IgA concentration, was about 30-fold less than that in serum. When related to only the 7 S IgA concentration of nasal secretions, the specific activity was about one-half that of serum. These studies are consistent with the following hypotheses: (a) circulating 7 S IgA is a source of part of the 7 S IgA found in nasal secretions. The remainder of the nasal secretion 7 S IgA may be synthesized locally in the tissues of the upper respiratory tract; (b) 11 S IgA in nasal secretions is not assembled from serum 7 S IgA components; and (c) 11 S IgA in nasal secretions is synthesized de novo in the tissues of the upper respiratory tract.


Susceptibility to infection and IgA deficiency in the infant.


Sex-linked thymic epithelial hypoplasia in two siblings. Attempt at treatment by transplantation with fetal thymus and adult bone marrow.


Palliative pituitary ablation.

Palliative pituitary ablation.


Study of the effect of experimentally induced endocrine insults upon pregnant and nonpregnant ewes. 3. ACTH and propylthiouracil administration and the production of polycystic ovaries.


Syndrome of cyanosis, digital clubbing, and hepatic disease in siblings.


Electron microscopical studies on the prostatic epithelium. II. Fine structures of the human prostatic cancer.


The diesel engine and atmospheric pollution.


Serum protein and immunoglobulin levels in tuberculosis.


A simplified procedure for serum butanol-extractable iodine.


Prostaglandins and nasal blood flow.

Prostaglandins and nasal blood flow.


Ileal conduit.

Ileal conduit.


Skeletal rearrangements of atisine derivatives.


Inhibition of the actinomycin-induced nucleolar change by thioacetamide in mouse hepatic parenchymal cell.


Diverse diseases, globulins, plasma cells, Russell bodies, Foà-Kurloff bodies, and the thymus: a unifying concept.


Simplified periodontal charting.

Simplified periodontal charting.


Ultrastructural features of in vitro propagated rat liver cells.


Progress in immunology in relation to clinical medicine.


Serum immunoglobulin levels in blood donors implicated in transmission of hepatitis.


Anaphylactic reaction to gamma-globulin.


Disulphide bridges of immunoglobin G-1 heavy chains.


Disulphide bridges of a human immunoglobulin G protein.


Plasma protein kinetics of the early transcapillary refill after hemorrhage in man.


The efffct of hormones on the sebaceous glands.


Pemphigus foliaceus presenting as dermatitis herpetiformis.


Photosensitive epilepsy: relationships between the visual evoked responses and the epileptiform discharges induced by intermittent photic stimulation.


Effect of thiocyanate, perchlorate and other anions on plasma protein-thyroid hormone interaction in vitro.


Studies on the mechanism of the inhibitory action of excess iodide on the release of radioiodine from the rat thyroid gland.


An essential role of thyroxine and triiodothyronine balance in establishing normal pituitary-thyroid feedback control in goitrogen-treated rats.


Action of snake venom on Rauscher virus.


Mucin histochemistry of human gallbladder: changes in adenocarcinoma, cystic fibrosis, and cholecystitis.


Is rubella an arbovirus?

Is rubella an arbovirus?


The hospital clinician's role, from two standpoints. 1. As a clinician sees it.


Lead in drinking water.

Lead in drinking water.


James Francis MacMahon, M.A., M.D. Dubl., D.P.M.


Elizabeth Whatley, M.B., B.Sc. Lond.

Elizabeth Whatley, M.B., B.Sc. Lond.


Edward Lewis, M.R.C.P.G.

Edward Lewis, M.R.C.P.G.


Positive results to serological tests for rheumatoid factor in New Guinea.


Maternofoetal transfer of gamma G immunoglobulins.


Some observations on pyroninophilic bodies in the gingivae.


Effect of histamine liberators on rat peritoneal mast cells and influence of antirheumatic agents.


Studies on several genetic hematologic traits of Mexicans. XV. The Gm allotypes of some Indian tribes.


The lethal effect of ethionine administered to guinea pigs.


Electron microscopical observations on the organization of artificial thrombi in the rabbit pulmonary artery.


Mucopolysaccharides of atherosclerotic plaques and platelets.


Blood coagulation and the effect of warfarin treatment on renal disease in NZB-NZW mice.


The coronary canalized thrombus: provenance, structure, function and relationship to death due to cornary artery disease.


Observations on the immunochemical analysis of human immunoglobulins.


Visual aid for drug identification.

Visual aid for drug identification.


Comparative studies of two models of allergic respiratory disease.


Improving inspector performance through training and visual aids.


X-chromosome linked inheritance of elevated thyroxine-binding globulin.


Suppression of human thyroid function by antibodies to bovine thyrotropin.


Inhibition of organic binding of iodine with graded doses of iodine in euthyroid men.


Cortisol production rate. VII. Hypothyroidism and hyperthyroidism in infants and children.


Studies on circulating immune complexes. 3. Factors governing the ability of circulating complexes to localize in blood vessels. The relationship between certain physicochemical properties of circulating immune complexes and their ability to localize in vessel walls during a state of increased permeability was studied. The ability to become deposited was related to the large size of complexes, rather than to their net charge or to a specific affinity between complexes and structures of vessel walls. Soluble complexes with sedimentation rates greater than 19S were capable of being entrapped along the vessel wall membranes, while complexes smaller than this were not. These large complexes were removed rapidly from the circulation, while smaller complexes persisted. Minimal levels of total complexes in the circulation necessary for detectable vascular localization were found to be as low as 15 microg antibody N/ml plasma. In experimental serum sickness, a disease known to be induced by circulating immune complexes, the development of vascular and glomerular lesions occurred almost exclusively in rabbits having large (greater than 19S) circulating immune complexes. Animals with smaller complexes did not show deposition of complexes in glomeruli or development of glomerulonephritis. Their incidence of vasculitis was markedly reduced.


Immunological analysis of rabbit anti-antibody systems. A study has been made of the production of antiidiotypic antibodies (anti-antibodies) arising during the immunization of 39 rabbits with 19 individual samples of rabbit anti-Proteus vulgaris x 19 antibodies adsorbed onto bacilli. In addition to the regular demonstration of antiidiotypic antibodies attention is drawn to the frequent occurrence of antiallotypic antibodies against molecules of immunoglobulin classes other than IgG, especially macroglobulins, which may arise during such immunization. In four cases attempts to raise autoantiidiotypic antibodies were unsuccessful, as expected. The idiotypic specificities (antigenic determinants) have been found mainly on IgG but also sometimes on IgM molecules. The individual specificity of the antiidiotypic antibodies appears to be absolute, as long as the antiallotypic antibodies are recognized and excluded; e.g., each idiotypic specificity is characteristic of only one single rabbit and of a single kind of antibody within that rabbit. These principles hold even when antibodies of rabbit families are examined: the parental idiotypic determinants could not be found in the offspring. In two samples tested the idiotypic specificities were found on the Fab fragment of IgG molecule but not on its antibody-combining site.


Immunoglobulins in NZB-BL mice. I. Serum immunoglobulin levels and immunoglobulin class of erythrocyte autoantibody. Determination of serum immunoglobulin levels in NZB and normal mice has indicated that an elevation of the gammaM-globulin level occurs in NZB mice. This can be demonstrated in young NZB mice well before other autoimmune manifestations are observed. A slight elevation of gammaM-globulin was also observed in NZB hybrid mice. Erythrocyte autoantibodies were analyzed by the direct Coombs' test with specific antiimmunoglobulin reagents. Autoantibodies in NZB mice can be of all immunoglobulin classes, although predominantly of gammaG(1)-class. In (NZB x NZC)F(1) hybrid mice, although Coombs' positivity develops around the same age as in NZB mice, there is a greater restriction of the autoantibodies into gammaM- and gammaG(1)-classes. Preliminary attempts to quantitate immunoglobulins coating NZB red cells have shown that there are approximately 400 molecules of gammaM and 5000 molecules of gammaG-globulin per NZB mouse red cell.


The gastrointestinal epithelium and its autochthonous bacterial flora. Colonization of the gastrointestinal tract by bacteria of the normal flora was followed by bacteriological and special histological techniques in mice from several colonies. These histological techniques were designed to preserve the intimate associations that become established between particular strains of microorganisms and the epithelium of the mucosa of certain areas of the gut. The findings were as follows: 1. The various strains of bacteria of the normal flora became established in the different areas of the guts of infant mice according to a definite time sequence. 2. The first types of bacteria that could be cultured from the gut were lactobacilli and Group N streptococci. Within the first day after birth, these bacteria colonized the entire digestive tract and formed layers on the stratified squamous epithelium of the nonsecreting portion of the stomach and of the distal esophagus. 3. The bacterial types that appeared next were coliforms and enterococci. From about the 9th to the 18th day after birth, these bacteria could be cultured in extremely high numbers from the cecum and the colon. Histological sections of those organs taken during the first 2 or 3 days of that interval revealed microcolonies of Gram-positive cocci in pairs and tiny Gram-negative rods embedded in the mucous layer of the epithelium. The microcolonies were well separated from the mixture of digesta and bacteria that occupied the center of the lumen; they may have consisted of the coliforms and enterococci mentioned above; but this possibility remains to be proved. 4. Histological sections also revealed that, at about the 12th day after birth, long, thin Gram-variable rods with tapering ends were present, side by side, with the small Gram-negative rods and Gram-positive cocci in the mucous layer. By the 15th day after birth, the fusiform bacteria formed thick layers in the mucus, and seemed to be the only bacteria remaining in that location. It has not yet been possible to enumerate these tapered rods by culture methods, but as judged by visual appearances in the histological sections, they seemed to outnumber all other bacteria in the cecum and the colon by a factor of as much as 1000. It must be stressed that these bacterial layers are readily disrupted and even washed away by conventional histological techniques; their discovery was largely due to the use of the special histological techniques described in the text. The bacteriological and histological findings described here constitute further evidence for the hypothesis that symbiotic associations exist between microorganisms and animals, and that a very large percentage of the bacteria in the gastrointestinal tract constitutes a true autochthonous flora. The constant occurrence of several distinct associations of bacteria with the special histological structures of the animal host renders obsolete the notion that the intestine constitutes a chemostat in which the bacterial populations are randomly mixed. For a full understanding of the ecology of the normal microflora, it is necessary to think of body surfaces as distinct microenvironments in which virtually pure cultures of a few species of microorganisms interact with their host and the adjacent microbial populations. Experiments based on this hypothesis are admittedly difficult to design, but on the other hand studies based on the assumption that microorganisms exist as mixtures in the gastrointestinal tract will be only of limited value and may often be misleading.


Thayer lectures.

Thayer lectures.


Studies on the control of antibody synthesis. II. Effect of antigen dose and of suppression by passive antibody on the affinity of antibody synthesized. The effect of antigen dose on the kinetics of circulating antibody synthesis and on antibody affinity was studied in a haptenic system. High doses of antigen resulted, early in immunization, in higher concentrations of antibody followed later in the immune response by decreased serum levels of antibody as compared with lower doses of antigen. The affinity of the initial antibody synthesized was very similar over a wide antigen dose range. Subsequently, however, a rapid rise in affinity was seen in animals immunized with low doses of antigen, while relatively little change in affinity was seen in animals immunized with higher antigen doses. Suppression of active antibody formation by passive antiserum led to an increase in antibody affinity. The results are discussed in terms of the mechanisms involved in the selection of a population of cells to participate in the immune response and the mechanisms whereby antigen dose and circulating antibody function to control antibody synthesis.


Thyrotropin deficiency in a child resulting in secondary growth hormone deficiency.


Comparison of serum protein bound iodine and thyroxine binding globulin saturation capacity values in Negro and white school children: ethnic difference.


Radioiodine uptake in subacute thyroiditis developing in an environment of endemic goitre.


Inhibition by human serum of the adipokinetic effect of a human pituitary lipid-mobilizing factor (LMF) in rabbits.


The lipid-mobilizing effect of some pituitary gland preparations. I. Evidence for a lipotrophic contamination with rabbit serum calcium-lowering effect in adrenocorticotrophin and human growth hormone preparations.


A study of endocrine function in the treatment of benign prostatic hypertrophy with megestrol acetate.


Protein-bound iodine variations. A study in some populations of the Western Pacific.


Renal tubular acidosis.

Renal tubular acidosis.


Nemaline myopathy: report of a fatal case, with histochemical and electron microscopic studies.


Myotonic dystrophy: its occurrence in childhood.


Nasal decongestant therapy.

Nasal decongestant therapy.


Rapid staining of Treponema pallidum in tissue.


Corneal vital staining.

Corneal vital staining.


Ultrastructural autoradiographic studies of keratohyalin granule formation.


Atypical gammaglobulinemias.

Atypical gammaglobulinemias.


Ultrastructure of the red blood cell.

Ultrastructure of the red blood cell.


Histamine binding capacity related to the supply of histamine.


Hydronephrosis as a cause of pleural effusion.


Subcellular localization of Entamoeba histolytica antigen.


A dependable silver impregnation for astrocytes in frozen and parafiin sections.


Specific DNA amounts and nuclear size in fish hepatocytes and erythrocytes.


Antibodies to folic acid and methotrexate obtained with conjugates of synthetic polypeptides.


Nodular lymphoid hyperplasia of the small intestine and hypogammaglobulinemia: theoretical and practical considerations.


Some immunologic properties of jackbean urease and its antibody.


Chromatographic and electrophoretic studies on PAS-positive components of serum macroglobulins.


Failure to detect alpha 1-acid glycoprotein by normal staining methods after zone electrophoresis.


A method for the rapid estimation of serum haptoglobin levels.


Initial axon collaterals from nerve cells in the lateral cervical nucleus.


Iodine kinetics in organification defect.


Trial of some dyes for wet staining of amoebae in cultures.


Effect of histamine liberators on peristaltic reflex.


Treatment of inoperable carcinoma of the bronchus by megavoltage X rays.


Some histophysiological aspects of Paneth's cells of mice as shown by histochemical and radioautographical studies.


Vaccination against leptospirosis: protection of hamsters and swine against renal leptospirosis by killed but intact gamma-irradiated or dihydrostreptomycin-exposed Leptospira pomona.


Half-periods of serum proteins in the dog.


Blood chemical and cellular changes in canine dirofilariasis.


Histamine in the cow: effect of histamine and estradiol administration on protein concentrations in milk.


Antibodies to papain. A selective fractionation according to inhibitory capacity.


The mechanism of inhibition of papain by its specific antibodies.


The interchain disulfide bonds of a human pathological immunoglobulin.


The inhibition of terminal oxidation by porphyrinogenic drugs.


Action verb materials developed for deaf children.


Attentional process in reading: the effect of pictures on the acquisition of reading responses.


Learning verbal and symbolic statements of mathematical rules.


The effects of heterologous immune globulins upon human cancer in vivo.


A family with sudanophilic leucodystrophy.


Electron microscopic studies of metachromatic leucodystrophy. II. Compound nature of the inclusions.


Immunoglobulin levels in healthy children.


Hereditary ectodermal dysplasia of anhidrotic type with increased protein-bound serum thyroxine.


Biochemical and histochemical observations on Krabbe's disease. (Globoid body diffuse sclerosis).


Bronchial asthma and recurrent pneumonia in children. Clinical evaluation of 14 children.


Quantitative evaluation of mongoloid gamma-globulins.


Ectopic ventricular tachycardia, hypokalemia and convulsions in alcoholics.


Aminosugars in cases of gastric ulcers. I. The amount of glucosamine and galactosamine in the human gastric mucosa.


Histoenzymatic demonstration of GGTP distribution in biobtic specimens from human gastrointestinal tract.


Psychopathological disorders in childhood: theoretical considerations and a proposed classification.


A rapid method for estimation of thyroxine secretion rate of cattle.


Induction of metaplastic secretory cells in pulmonary alveoli.


Serum enzyme changes after hepatic dearterialization in man.


Fluorescein-labeled beta-glucosidase as a bacterial stain. Fluorescein isothiocyanate-labeled beta-glucosidase was used as a simple staining reagent with selected gram-positive and gram-negative organisms. Staining in situ appeared to be dependent on the presence of accessible glycosidic-type linkages in the bacterial cell wall. Extensive wall damage or lysis did not occur when stained cells were suspended in washing and mounting solutions. The apparent specificity of labeled enzyme for wall substance was tested by blocking reactions, staining of isolated cell walls, and failure to stain substances lacking appropriate glycosidic linkages. Severe cell wall lesions were produced after prolonged contact with labeled enzyme, and this phenomenon may also be related to staining specificity. Gram-negative organisms and spores were poorly stained unless protected glycopeptide substrate was previously exposed by treatment of cells with thioglycolic acid or dilute alkaline sodium hypochlorite solution. A potential for staining tissues and cell lines may also exist. Some possible applications of labeled enzymes are briefly discussed.


Splenic ultrastructure in rats treated with methylcellulose.


Pulmonary capillary thrombosis in experimental pneumococcal septicemia.


Atriogenic mitral valve reflux: diastolic mitral incompetence following isolated atrial systoles.


Group psychotherapy and symbol formation.


Photochemical reactivities of exhausts from 1966 model automobiles equipped to reduce hydrocarbon emissions.


Hypothyroidism in diabetics.

Hypothyroidism in diabetics.


Large doses of radioiodide in Graves' disease: effect on ophthalmopathy and long-acting thyroid stimulator.


Action of streptomycin, dihydrostreptomycin, neomycin and kanamycin on the ampullar receptors of the frog.


The inhibitory effect of 6-azauridine on reovirus multiplication.


Pyrrolid-2-one-5 carboxylic acid involvement in the biosynthesis of rabbit immunoglobulin.


A histochemical study of immune destruction of the lymphopoietic system.


A new method for fluorescently labelling and staining trypanosomes.


A rapid staining modification of Guard's sex chromatin technic.


Rheumatoid arthritis with secondary amyloidosis and malabsorption syndrome. Effect of D-penicillamine.


Sequence of immunoglobulin changes resulting from an attack of infectious mononucleosis.


Comparative cellular and immunochemical studies of two cases of pyroglobulinemia.


A reappraisal of Kartagener's syndrome.

A reappraisal of Kartagener's syndrome.


Immunoglobulins in infectious mononucleosis.


Generalized Pneumocystis carinii infection with severe idiopathic hypoproteinemia.


Effect of renal hemotransplantation on the metabolism of the light chains of immunoglobulins.


Quantitation of conformational changes on chemical modification of proteins: use of succinylated proteins as a model.


Viability of human eye bank cornea.

Viability of human eye bank cornea.


The lipolytic action of human placental lactogen on isolated fat cells.


Cyclophosphamide-induced chimerism.

Cyclophosphamide-induced chimerism.


Leucine incorporation in axonal swellings of vitamin-E-deficient  rats.


Antigens in immunity. XV. Ultrastructural features of antigen capture in primary and secondary lymphoid follicles. This paper describes the trapping of antigen in lymphoid follicles of rat popliteal lymph nodes as revealed by electron microscopic radioautographs following injection of (125)I-labeled Salmonella adelaide flagella and other materials. The antigen was taken up vigorously, and to an approximately equal extent, by both primary and secondary follicles. The rate of uptake was faster in preimmunized than in virgin adult rats. The bulk of the antigen in follicles was extracellular, and persisted in this location for at least 3 wk. Label was most frequently found at or near the surface of fine cell processes. Many of these were branches of dendritic follicular reticular cells. Such processes interdigitated with equally fine processes of lymphocytes, creating an elaborate meshwork. In some cases, antigen was found between lymphocytes which appeared to be in close apposition. Occasionally, a few grains appeared over lymphocyte nuclei and study of serial sections suggested that this probably represented true entry of small amounts of antigen into lymphocytes. The characteristic "tingible body" macrophages (TBM) of germinal centers appeared to play only a secondary role in follicular antigen retention. They showed degrees of labeling over their phagocytic inclusions varying from negligible to moderately heavy. Moreover, follicles lacking or poor in TBM retained antigen just as effectively as those containing numerous TBM. The hypothesis is advanced that TBM may be derived from monocytes that migrate down from the circular sinus. Follicular localization of three other materials was also studied, though not in such detail. These were (125)I-HSA complexed to anti-HSA: (125)I-labeled autologous IgG; and (125)I-monomeric flagellin. All of these showed the basic features of intercellular, membrane-associated deposition noted with (125)I-flagella. The role of follicular antigen depots in immune induction is discussed. The tentative conclusion is reached that follicular antigen in a primary follicle encounters natural antibody on the surface of certain antigen-reactive lymphocytes. The resultant reaction causes blast cell transformation and eventually the genesis of a germinal center.


[On the reaction of phenanthridine with alkylmagnesium halide].


Confirmation of the freudian psychosexual stages utilizing sexual symbolism.


Arthritis of rats inoculated with granuloma pouch exudate.


Protein concentrations in the umbilical cord plasma of premature and mature infants.


Clinical observations on hay fever due to Japanese cedar pollen.


The specific inhibition of in vitro anaphylaxis and histamine release by dialyzable material from ragweed pollen.


Effect of 6-aminonicotinamide and of added vitamin A on fusion of embryonic rat palates in vitro.


Iodine deficiency, a permissive condition in the development of endemic goiter.


Immunogenic properties of babesial serum antigens.


The ultimobranchial origin of calcitonin.


Immune imbalance in dysgammaglobulinaemia type IV.


A third allele at the phenylalanine-hydroxylase locus in mild phenylketonuria (hyperphenylalaninaemia).


Effect of malnutrition on activity of two enzymes concerned with aminoacid metabolism in human liver.


Amiloride ('MK 870') in patients with ascites due to cirrhosis of the liver.


A new endocrine gland.

A new endocrine gland.


Comparison of chlorpropamide and metformin treatment on weight and blood-glucose response of uncontrolled obese diabetics.


The cow as a model for investigating natriuretic activity.


Cadmium and metabolism of albumin.

Cadmium and metabolism of albumin.


99mTc:a versatile isotope.

99mTc:a versatile isotope.


Plasma phospholipids and platelet stickiness in multiple sclerosis.


Rheumatoid pleuritis?

Rheumatoid pleuritis?


Control of anticoagulant treatment.

Control of anticoagulant treatment.


Carcinogen in jute processing.

Carcinogen in jute processing.


Hospital admissions and investigations.

Hospital admissions and investigations.


The clinician and the computer.

The clinician and the computer.


Bedsores.

Bedsores.


Unusual reaction to B.C.G.

Unusual reaction to B.C.G.


X-ray inactivation of histamine.

X-ray inactivation of histamine.


Purpura with hypogammaglobulinaemia.

Purpura with hypogammaglobulinaemia.


Gastroenteritis due to Escherichia coli.


Bacteriology in the surgery.

Bacteriology in the surgery.


A national chemical-pathology service.

A national chemical-pathology service.


Snowburn.

Snowburn.


Splenic cultures in leukaemia and septicaemia.


A non-carcinogenic cigarette?

A non-carcinogenic cigarette?


Venous stasis and fibrinolysis.

Venous stasis and fibrinolysis.


Hiccup.

Hiccup.


Death from paraquat in a child.

Death from paraquat in a child.


Insulin response in chronic alcoholism.

Insulin response in chronic alcoholism.


Bacterial endocarditis.

Bacterial endocarditis.


Renal allograft rejection.

Renal allograft rejection.


Medical students and general practice.

Medical students and general practice.


Folic acid and neuropathy in epilepsy.

Folic acid and neuropathy in epilepsy.


Pain after head injury.

Pain after head injury.


Insulin response to glucagon.

Insulin response to glucagon.


A special fluoridated school milk?

A special fluoridated school milk?


Foetal blood-glucose level.

Foetal blood-glucose level.


Methotrexate and lymphocyte/target-cell interaction.


M.C.Q. and the membership.

M.C.Q. and the membership.


Insulin in urine.

Insulin in urine.


Prostaglandins and platelets.

Prostaglandins and platelets.


XYY males in a Melbourne prison.

XYY males in a Melbourne prison.


Platelet behaviour and plasma phospholipids in multiple sclerosis.


Cerebral gigantism.

Cerebral gigantism.


Commercial varieties of nuclear fast red; their behaviour in staining after autoradiography.


Correlation of crystal growth with the staining of axons by the Golgi procedure.


Thin-layer lactose agar for pollen-tube culture of Tradescantia to enhance planar distribution of chromosomes.


Straight OsO4 versus glutaraldehyde-OsO4 in sequence as fixatives for the granular vesicles in sympathetic axons of the rat pineal body.


Enhancement of the affinity of nucleoli and chromosomes for zinc by treatment with chromic acid.


A simple toluidine blue--basic fuchsin stain for spermatozoa in epoxy sections.


Staining of Paneth cells with Best's carmine after methylation.


Leukocyte alkaline phosphatase.

Leukocyte alkaline phosphatase.


Some problems on the leuco-dye-peroxide reaction. The 31st report of histochemical study of peroxidase.


Effect of daylight projection of film loops on learning badminton.


Cliical aspects of lymphogranulomatosis maligna.


Histological and histochemical observations on the eosinophilic vesicles found in the head eidermis of Blepsias cirrhosus (Pallas). A preliminary report.


The specificity of uptake of foreign proteins by coelomocytes of the purple sea urchin.


A new stain for bile canaliculi.

A new stain for bile canaliculi.


On the behaviour of leucocytes in immature leukaemias in short-term cultures.


The human immunoglobuins.

The human immunoglobuins.


Serum protein-bound iodine and resin uptake of triiodothyronine during normal pregnancy.


Changes in the vascular bed of the thyroid gland in dogs under the influence of thymidazol.


Histochemical demonstration of spermatozoa in spots by the method of Feulgen.


Palliative treatment of inextirpable esophageal cancer.


New approaches to the physiology of histamine.


Auto-interpretation of dreams and art productions. Hypoanalysis of a case of amnesia.


Attenuation of anticipation: a therapeutic use of lysergic acid diethylamide.


Which shall it be: mass education or mass persuasion for health?


The second look operation for carcinoma of the colon after administration of 5-fluorouracil.


Comparison of IgG and IgM antibodies specific for uridine.


Source of the histamine released during damage to the gastric mucosa by acetic acid.


Evidence for the IgG nature of complement-fixing (CF) antibodies to adenovirus type 12 hamster tumor neoantigens.


Properties of highly purified human properdin.


Passive anaphylaxis in mice with gamma-G antibodies. I. PCA and RPCA reactions with homologous and heterologous antibodies.


A cellulose mercurial: preparation, properties and use in antibody purification.


Reactivity of human immunoglobulins in amebiasis.


Immune lytic transformation: a state of irreversible damage generated as a result of the reaction of the eighth component in the guinea pig complement system.


Influenza virus neutralizing antibody in human respiratory secretions.


Cadaveric renal transplantation.

Cadaveric renal transplantation.


Abnormal serum immunoglobulins occurring with reticular neoplasms in a inbred strain of mouse.


YY syndrome in an American Negro.

YY syndrome in an American Negro.


Changes in the cancer risk associated with obstetric radiography.


Outcome for the foetus of mothers receiving prednisolone during pregnancy.


Urinary steroid excretion pattern in diabetes mellitus.


The community-care unit.

The community-care unit.


Live, attenuated mumps-virus vaccine.

Live, attenuated mumps-virus vaccine.


Hereditary alpha-1-antitrypsin deficiency.


Effect of 1-methyl-2-mercaptoimidazole (methimazole-tapazole on DNA content of the chicken thyroid gland.


Effect of Moloney virus on protein-bound iodine levels in CFW mice.


Hypergammaglobulinemia in experimental liver injury.


A DEAE-cellulose chromatographic separation of Co 57 vitamin B12 binders in normal human serum.


Steroid treatment of the nephrotic syndrome in adults.


Mixed IgA-IgG cryoglobulinemia. Immunological studies and case reports of three patients.


Plasma cell dyscrasias. Current clinical and biochemical concepts.


Macroglobulinemia with bone destruction.


Creation of atrial septal defects by catheter as palliation of complete transposition.


Isolation and continuous cultivation of Trypanosoma theileri in media containing tissue culture fluids.


The cytologic diagnosis of cerebrospinal fluid.


Mode of action of anti-lymphocyte globulin. I. The distribution of rabbit anti-lymphocyte globulin injected into rats and mice.


Mode of action of anti-lymphocyte globulin. II. Changes in the lymphoid cell population in rats treated with anti-lymphocyte globulin.


Studies on the control of antibody synthesis. Effect of antibody affinity upon its ability to suppress antibody formation.


The immune response to influenza virus. 3. Changes in the avidity and specificity of early IgM and IgG antibodies.


Fowl antibody. IX. The different responses to the hapten and carrier moieties of 2,4-dinitrophenyl-bovine gamma-globulin.


Fowl antibody. X. The purification and properties of an antibody to the 2,4-dinitrophenyl group.


Studies on synthetic polypeptide antigens. XIX. Immunogenicity and antigenic site structure of intramolecularly cross-linked polypeptides.


Hepatocellular carcinoma in association with a specific fetal alpha-1-globulin, fetoprotein.


Infusion excretory urography. Report of 100 cases using Renografin 60.


Hyperthyroidism attributable to a hyperfunctioning thyroid carcinoma.


The development of immunoglobulin levels in man.


Lactate dehydrogenase isoenzymes in hyperplasia and carcinoma of the prostate: a clinical study.


Human infection acquired in the laboratory.


Haemolytic efficiency of rabbit IgG anti-Forssman antibody and its augmentation by anti-rabbit IgG.


Effects of dehydration on blood viscosity and on distribution of plasma proteins in experimental macroglobulinaemia.


Immunohistochemical study of allergic encephalomyelitis.


The clinical significance of plasma thyroid-stimulating ctivity in hyperthyroidism.


An audio visual teaching unit for radiology.


The acquisition of electrophysiological data for use in a digital computer.


EEG activation of epileptics following sleep deprivation: a prospective study of 114 cases.


Electrocortical recruiting responses during classical conditioning.


The nature of sleep attack and other symptoms of narcolepsy.


Cortical polarization and experimentally produced delta waves in the cat.


Frequency and phase of hippocampal theta activity in the spontaneously behaving cat.


Hippocampal responses evoked by stimulation of the prepyriform cortex in the rat.


The relative incidence of the B-mitten EEG pattern in process and reactive schizophrenia.


A technique for recording activity of subcortical neurons in moving animals.


Studies concerning the value of photic stimulation in different types of eilepsy.


The duration of bilaterally synchronous 3 c/sec spike and wave rhythms.


Development of the EEG in health infants during the first year of life, illustrated by frequency analysis.


Vegetative changes in response to electrical brain stimulation.


Polygraphic recordings during syncope.

Polygraphic recordings during syncope.


Methods for studying the modifications in frequency spectrum of myo-potentials at slow and fast muscle contractions.


Frequency analysis of the interference pattern during voluntary effort.


Frequency analysis of the EMG in neuromuscular disorders.


The effects of subparalytic doses of D-tubocurarine on neuromuscular transmission.


Variability in propagation velocity in human single muscle fibres.


Thalamo-cortical relations during spontaneous barbiturate spindles.


Patterns of spontaneous barbturate spindle activity within the thalamus.


Localization of subcortical barbiturate spindles.


Sensitivity of cortcal and thalamic barbiturate spindles to hypoxia.


Sympathetic inhibition of the urinary bladder.


Electromyographic studies of facial muscle activity in speech.


EMG changes in a patient with adynamia episodica familiaris.


A comparison of the electrically induced stretch reflex in normals, spastics and Parkinsonians.


The isoelectric electroencephalogram.

The isoelectric electroencephalogram.


Electrosleep and brain function.

Electrosleep and brain function.


EEG computer audiometry.

EEG computer audiometry.


Concerning myotonic reactions.

Concerning myotonic reactions.


Fast spindled activity in the waking EEG.


Studies on CNV: interest of recording its progressive construction during summation.


Experimentally induced intracranial hypertension and the EEG.


Hypoglycemic (Tolbutamide) provocation compared with the Bemegride provocation method.


Neurophysiological identification of thalamic nuclei during stereotactic thalamotomy for pain.


Sensory control of cortical excitability: neurophysiological mechanisms in the prepiriform cortex of the cat.


EEG in dialysis.

EEG in dialysis.


Some properties of the stimulatory effect of thyroid hormones on amino acid transport by embryonic chick bone.


Studies on the preservation and organization of DNA-containing regions in a blue-green alga, a ctochemical and ultrastructural study.


Staining of basement membranes and assocated structures by the periodic acid-Schiff and periodicacid-silver methenamine techniques.


Free thyroxine in serum in relation to thyroid function.


Obstetric determinants of rhesus sensitisation.


Cyclophosphamide treatment of renal disease in (NZB x NZW) F1 hybrid mice.


Direct immunofluorescent identification of respiratory syncytial virus in throat swabs from children with respiratory illness.


Failure of endogenous stimulation of secretin and pancreozymin release to influence serum-insulin.


Encephalopathy and visceral fatty infiltration of probable toxic aetiology.


Interferon inducers.

Interferon inducers.


Cystic fibrosis o the pancreas. A generalised disturbance of water and electrolyte movement in exocrine tissues.


The problems of trawlermen.

The problems of trawlermen.


The biological bomb.

The biological bomb.


Food from abrod.

Food from abrod.


Schizophrenia en famille.

Schizophrenia en famille.


Pleural mesothelioma in an asbestos worker.


Outcome of pregnancy when legal abortion is readily available. An evaluation of the effect of the fairly liberal Swedish abortion law on the incidence of criminal abortions and of deliveries was conducted.  The outcome of all notified pregnancies in Stockholm from 1950-1965 was registered.  From 1950-1961, the incidence of deliveries varied inversely with the incidence of legal abortion; from 1961, the relationship between the 2 variables was not as clear.  The percentage of ectopic pregnancies, missed abortions, and hydatidiform moles remained constant at 1 until 1959, after which time ectopic pregnancies declined due to treatment of salpingitis with antibiotics.  The criminal abortion rate remained constant during the period; in the last 4 years, it has declined somewhat.  This fact would indicate that the abortion law in its present form does not contribute to a reduction in criminal abortion.  The figures also show that women whose abortion requests are denied do not regard criminal abortion as an acceptable alternative.  It is still too early to conclude that there is an association between the substantial increase in legal abortions between 1962-1965 and the decline in criminal abortions.  Only the development of a safe, simple, and cheap contraceptive will help to reduce the illegal abortion rate further.


The super-consultant system.

The super-consultant system.


Antibiotics and the common cold.

Antibiotics and the common cold.


Assessing the chronic bronchitis.

Assessing the chronic bronchitis.


A non-carcinogenic cigarette?

A non-carcinogenic cigarette?


Splenic aspiration in acute leukaemia.

Splenic aspiration in acute leukaemia.


Escalator injuries.

Escalator injuries.


Risks of peritoneal catheter insertion.

Risks of peritoneal catheter insertion.


Carbohydrate metabolism in the newborn.

Carbohydrate metabolism in the newborn.


Diazepam for treatment of phobias.

Diazepam for treatment of phobias.


Infectious mononucleosis.

Infectious mononucleosis.


Anatomic methods for study of the bulbus oculi.


A technique for staining and separating corneal endothelium.


Immunologic competence of thymectomized neonatal calves.


Posttherapeutic myxedema. Relative occurrence after treatment of hyperthyroidism by radioactive iodine (131-I) or subtotal thyroidectomy.


Hyperthyroidism and renal tubular acidosis.


Uptake of radioiodinated protein and amino acid by mouse glioma and brain.


Content of polycyclic hydrocarbons in crude vegetable oils.


The occurrence of polycyclic aromatic hydrocarbons in coconut oil and their removal.


Fetal and neonatal toxicity of drugs.

Fetal and neonatal toxicity of drugs.


Monitoring cerebral blood flow, metabolism and EEG.


Comparison of EEG correlates of reinforcement, internal inhibition and sleep.


Alterations in the non-specific cortical afference during hyperventilation.


Electrophysiological studies of learning in split brain cats.


Correlation of reticular and cochlear multiple unit activity with auditory evoked responses during wakefulness and sleep. I.


Effects of caudate nucleus stimulation and lesions on single cell activity in the anterior hypothalamus.


Effects of carbon dioxide on the alpha frequency and reaction time in humans.


Human cerebral evoked responses to odorous stimuli.


A new electrode material for multipurpose bio-medical application.


Pattern reading of the clinical electroencephalogram with a digital computer.


A thermode for rat brain.

A thermode for rat brain.


An electrically operated micro-tap.

An electrically operated micro-tap.


Practical applications of quantitative electroencephalography: changes in the spontaneous variability of the EEG provoked by cerebral tumors.


Quantitative electroencephalography: topographic differences in the responses in cerebral electrogenesis provoked by overbreathing.


A theoretical model of the alpha average.


Study of the average alpha rhythm in the child: attempt at clinical application.


Maturation of somatosensory evoked potentials in man.


Visual evoked potentials and frequency of stimulation.


Variations in the average visual response in relation to the alpha phase ("autostimulation").


Evaluation of the depth of coma in the child by the evoked potential technique.


Preliminary findings concerning the expectancy wave and the visually deficient child.


Investigation of evoked potentials of vestibular origin in man.


Radiotelemetric recordings of the electroencephalograms of civil aviation pilots during flight.


Electro-clinical pharmacological "focalization" of certain experimental epilepsies; effect of a product related to Gaba.


Influence of cortical topectomies on penicillin epilepsy.


Effects of intravenous Valium on the EEG changes caused by intravenous injection of Cardiazol; proposals for perfecting "Cardiazol activation".


Multiple focal origin of certain cortical epilepsies.


A case of oculoclonic attacks with surgical verification.


The EEG in major softenings and hemispheric cerebral hemorrhages.


An EEG study of cases with mixed ictal and somatic manifestations.


The EEG in complicated and symptomatic migraine.


Clinical and EEG changes in tetanus during intensive and prolonged treatment with diazepam.


Preliminary results of an EEG study of the effects of hyperbaric treatment of experimental carotid gas embolism in Papio papio.


Tonic activity and the stages of sleep in the mental patient.


Ocular paroxysmal state. Influence on the vestibular caloric responses.


Value of monocular oculography in nystagmography.


Further data on directional preponderance in nystagmography.


Electronystagmography and psychiatry.

Electronystagmography and psychiatry.


Comparison of electronystagmography (ENG), photoelectronystagmography (PENG) and special devices with contact lenses for oculography.


Electronystagmographic aspects of tumours of the cerebello-pontine angle.


Nystagmographic study of the galvanic vestibular response.


A proposed vestibular electronystagmographic (ENG) semiology.


Nystagmography of the caloric responses in cranial trauma.


Vestibular and nystagmic thresholds. Value of the study of tonic movements of the eyeballs by DC recording.


The value of vector oculography in the study of disturbances of perceptive structuration.


Viral diseases of the vestibular apparatus and electronystagmography.


Symposium on the use of sinusoidally modulated light for the study of visual mechanisms in normal subjects, patients and animals (dogs).


Developmental analysis of EEG abnormalities in juvenile delinquents.


EEG changes in patients with heart block.


An unsuccessful attempt at the extinction of photogenic epilepsy.


EMG study of a patient with myasthenic syndrome, small cell carcinoma of the lung.


EEG in Addison's disease.

EEG in Addison's disease.


Relationship between the EEG and employment status of epileptic patients.


Sex differences in the phase analysis of the human EEG.


Left-sided predominance of temporal foci.


A survey of enigmatic EEG patterns in psychiatric practice.


The six per second spike and wave pattern: further observations.


"Spike-waves" in brain tumors and other disorders without and with seizures.


Correlative EEG and mercury scan findings in 80 cases of brain tumor suspect.


ON, OFF and "following" responses to visual stimulation in the full-term human newborn.


Evaluation of computer technics in EEG analysis.


A diffusion theory of membrane excitation.


Electrocortical phase patterns in the semi-isolated cortex.


Multiple epileptogenic foci revealed by depth recording.


Amygdaloid influences on diencephalic and mesencephalic reticular systems.


The effect of motivation on the contingent negative variation (CNV).


Respiratory effects on the contingent negative variation.


Eye movements during the alert state (psychophysiological correlations under resting conditions).


Chronic sclerosing osteomyelitis of the mandible: report of case.


A human pigmentary dilution based on a heritable subcellular structural defect--the Chediak-Higashi syndrome.


Studies on blisters produced by friction. II. The blister fluid.


Cordotomy: 1967.

Cordotomy: 1967.


Hepatitis among missionaries in Ethiopia and Sudan. Susceptibles at high risk.


Impaired delayed hypersensitivity in an aging population. Association with antinuclear reactivity and rheumatoid factor.


The ultrastructure of normal and otosclerotic human stapes. (Preliminary studies).


Combined growth hormone and thyroid deficiency in a child.


Audio-visual aids in medical teaching.

Audio-visual aids in medical teaching.


A comparison of the findings from the corneal epithelium of the normal and the buphthalmic rabbit eye.


Monoamine oxidase activity in the various structures of the mammalian eye. Histochemical staining and quantitative chemical study.


The formation of synaptic junctions in developing rat brain: a quantitative electron microscopic study.


The effect of iodination on antifibrinogen antibodies with respect to precipitating and adsorption activities.


The synthesis of fluorescent penicilloyl haptens and their use in investigating 'penicillin' antibodies by fluorescence polarization.


Structural characteristics of the Fc' fragment of human gamma-G-globulin.


Sub-groups of G-myeloma globulins of type K and type L.


Further studies on the adsorption of antibody by guinea pig lung and the subsequent fixation of antigen.


Muskegon Medical Society begins use of video tape recorder for education.


Structure and function of immunoglobulins. Relation to allergy.


Inhibitory properties of serum proteins on the enzymatic sequence leading to lysis of red blood cells by snake venom.


Maternal-foetal iodine metabolism in the rabbit, 3. 131-I storage by foetal organs.


On the mode of action of UV-light: effect of UVA-rays on mast cells in vivo.


Characteristics of Cytophaga psychrophila (Borg) isolated during outbreaks of bacterial cold-water disease. Characteristics of 10 strains of Cytophaga psychrophila isolated during a number of epizootics of bacterial cold-water disease were compared. Morphological, cultural, biochemical, and serological data showed that the organisms were very closely related. The isolates exhibited gliding motility, formed neither fruiting bodies nor microcysts, were actively proteolytic, and grew only at low temperatures. Data presented extend the description of C. psychrophila.


Insulin sensitivity and 131-I insulin metabolism in juvenile-type diabetics.


Hypofibrinogenaemia in acute leukaemia with extensive fibrinous pericarditis.


Comparative lipid biochemistry. V. The neutral lipid plasmalogens and other lipids of some specializwdspecialized sebaceous glands.


An electrophysiological and pharmacological study of visceral smooth muscle and its innervation in a mollusc, Poneroplax albida.


Studies on plasma membranes. IV. The ultrastructural localization and content of sialic acid in plasma membranes isolated from rat liver and hepatoma.


Fine structure of gametes of Nereis limbata (Annelida) before and after interaction.


Factors influencing steroid hydroxylases in liver microsomes.


Effect of drugs on mast cells.

Effect of drugs on mast cells.


Role of local gamma-A-immunoglobulins in immunity.


Sex chromatin in cervical smears.

Sex chromatin in cervical smears.


Endometrial cytologic study in asymptomatic postmenopausal patients.


Study of developmental anomalies in the spontaneously aborted fetus.


Enzyme cytochemistry of benign and malignant cells in pleural and peritoneal fluid.


Influence of thalidomide on fertility and on reproductive organs in rats. Preliminary communication.


Analysis of quaternary ammonium compounds and hexachlorophene by thin-layer chromatography and agar diffusion bioautography.


Individual study and educational technology.


Projectors.

Projectors.


The importance of the two halves of human immunoglobin light chain in recombination with the heavy chain.


The biochemistry of affective disorders.


Cytochemical studies of polyoma virus infection. II. Lipids.


Histochemical studies of KB cell cultures infected with parainfluenza 3 virus. I. General evaluation of cytopathic changes in cell cultures.


A hemolytic plaque technique for enumeration of cells producing antibody against penicillin.


Actions of anaphylatoxin on circulation and respiration of the guinea pig.


Immunologic aspects of ataxia-telangiectasia.


Bacterial endocarditis in a dog.

Bacterial endocarditis in a dog.


The ultrastructure of normal and pathological IgM immunoglobulins. Free IgM immunoglobulins were examined in the electron microscope using the negative contrast technique. Normal human and rabbit IgM and Waldenström macroglobulins were indistinguishable from one another and revealed flexible spider-like particles with five appendages joining a central ring. The average total span of the molecules was 300 A. The appendages were about 125 x 30 A; the central ring had an outer diameter of approximately 100 A and an inner diameter of 40 A. Some purified 19S IgM preparations tended to form massive aggregates (>/=50S) which, when examined in the electron microscope, revealed enormous clumps of IgM molecules whose appendages were entangled with one another. Electron microscopy of reduced-alkylated IgM revealed total absence of intact spider-like molecules. The predominating structure observed was a round electron-dense knob about 50 A in diameter which in some cases had a fine fiber-like extension with approximate dimensions 100 x 15 A. Rabbit and human IgM molecules with antibody activity to poliovirus dried in sodium tungstosilicate on a carbon film as in preparation for electron microscopy were shown to retain nearly 100% of their poliovirus neutralizing activity after redissolving in a physiological buffer.


Papain digestion fragments of human IgM globulins. Papain digestion of two Waldenström IgM globulins produced a high amount of small peptides and resulted in the formation of two end products, the Fabmicro and Fcmicro fragments. The Fcmicro fragment is characterized by a fast electrophoretic mobility, a high content in carbohydrate, and a high molecular weight. It was demonstrated that this fragment is made of heavy chain pieces belonging to several disulfide-linked monomeric subunits, presumably representing the carboxy-terminal end of the micro-chains. Fc fragments from the two macroglobulins could not be distinguished immunologically. An appreciable proportion of IgM molecules apparently underwent degradation without the formation of a stable Fc fragment. An Fc-like fragment, analogous to the reduced Fc fragment, was obtained at early stages of papain digestion of the IgM subunits. The Fabmicro fragment, with slow and individually distinct electrophoretic mobility, bears many physicochemical and immunological similarities to the Fabgamma fragment. It consists of one light chain and one Fd piece, both of which were isolated. The interaction of these two constituents was demonstrated by gel diffusion studies. Fab fragments of both IgM globulins were resolved into two subpopulations with different electric charges. In addition to these fragments, intermediary split products were observed at early stages of the degradation process, together with a high yield of small peptides mainly derived from the papain-sensitive region of the heavy chains. Immunologic data strongly suggested that this segment of micro-chains is situated between the Fd piece and the portion included in the Fc fragment. Several experiments indicated the importance of conformational antigenic specificity in both Fab and Fc regions of the IgM globulins.


Pathogenesis of the glomerulonephritis of NZB/W mice. The development of glomerulonephritis in NZB/W mice is closely related to the formation of antinuclear, particularly anti-DNA, antibodies. The developing inflammatory glomerular lesions are characterized by the deposition of gammaG- and beta(1C)-globulins plus DNA and possibly other nuclear antigens, presumably as complexes, in a granular to lumpy pattern along the capillary walls and in the mesangia. Elution studies revealed the gammaG-globulin in the glomeruli to be largely gammaG(2A)-type antibody to soluble nuclear antigens. Enhancement of the antinuclear antibody response by active immunization of young NZB/W mice with DNA-methylated BSA hastens the development and increases the severity of the glomerulonephritis. Similarly, injections of soluble DNA into NZB/W mice with circulating anti-DNA antibodies but with as yet little nephritis causes rapid progression of nephritis.


The response of cultured mammalian cells to diphtheria toxin. II. The resistant cell: enhancement of toxin action by poly-L-ornithine. We have investigated the response of the resistant mouse L cell to diphtheria toxin. Intact cells and cell-free systems were studied. It was determined that the cell-free system is as sensitive to toxin as those from sensitive reticulocyte, HeLa, and KB cells previously studied. Poly-L-ornithine, reported to stimulate macromolecular uptake, enhanced toxin activity under conditions which also stimulated acid phosphatase activity. Resistance, in the L cell, appears to be linked to the cell membrane and the process of macromolecular uptake, and not to any intrinsic property of either the polyribosomes or associated protein synthesizing factors. Because of the unique way in which diphtheria toxin inhibits protein synthesis, the ability of poly-L-ornthine to enhance this action provides convincing evidence that poly-L-ornithine stimulates a true absorption of macromolecules and not just increased surface adsorption.


Autologous immune complex nephritis induced with renal tubular antigen. II. The pathogenetic mechanism. The pathogenetic mechanism involved in a form of experimental allergic glomerulonephritis induced by immunization of rats with renal tubular antigen has been investigated. A single immunization with less than a milligram of a crude renal tubular preparation, probably containing less than 25 microg of the specific nephritogenic antigen, is effective in the induction of this form of chronic membranous glomerulonephritis. In the nephritic kidney autologous nephritogenic tubular antigen is found in the glomerular deposits along with gamma-globulin and complement. When large amounts of antigen are injected during induction of the disease the exogenous immunizing antigen can also be detected in the glomerular deposits. It appears that this disease results from the formation of circulating antibodies capable of reacting with autologous renal tubular antigen(s) and the deposition of these antibodies and antigen(s) plus complement apparently as immune complexes in the glomeruli. This pathogenetic system has been termed an autologous immune complex disease and the resultant glomerulonephritis has been similarly designated.


Heterogeneity of rabbit IgM antibody as detected by C'1a fixation. The C'1a-fixing properties of purified rabbit IgM anti-benzenearsonate antibody were determined. When tested with sheep erythrocytes to which hapten had been coupled by diazo linkage, the number of C'1a molecules fixed was 21% of the number of IgM antibody molecules bound to the erythrocyte surface. This was not due to loss of C'1a-fixing capacity during the purification procedure. Preparative electrophoresis of the antibody concentrated C'1a-fixing molecules in the anodal region so that antibody fractions with greater C'1a-fixing capacity were obtained. The demonstration that C'1a fixation is a property of a subpopulation of IgM molecules provides evidence for previously unrecognized micro-chain heterogeneity.


Diet and infrequent peritoneal dialysis in uremia.


Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers. The composition of various isolated antibodies was determined by quantitative analyses for heavy chain subgroups and light chain types. Certain antibodies such as anti-tetanus toxoid and anti-A isoagglutinins were predominantly of the major gammaG1-type. However, a high preponderance of molecules of the minor gammaG2-subgroup was found for antibodies to dextran, levan, and teichoic acid. These findings explain some unusual features previously noted for anti-dextrans such as weak PCA reactions and lack of Gm antigens. Studies of several isolated antibodies from single heterozygous individuals showed a selective absence of genetic markers in certain antibodies and their presence in others. The "allelic exclusion" principle was clearly evident in the isolated antibodies of two different individuals. Large differences in the ratio of kappa to lambda light chains were observed for the same type of antibody from different individuals. Subfractionation of dextran antibodies by affinity for specific glycosidic linkage or combining site size produced marked changes in the ratios. The isomaltohexaose eluates of the dextran antibodies from two subjects were primarily kappa and the isomaltotriose eluates were predominantly lambda. The one anti-levan antibody studied was uniquely homogeneous, consisting exclusively of gammaG2-heavy chains and kappa light chains. By these criteria as well as others, it closely resembled myeloma proteins.


Urinary lysozyme, ribonuclease, and low-molecular-weight protein in renal disease.


Quinine therapy and peritoneal dialysis in acute renal failure complicating malarial haemoglobinuria.


Placental transfusion-rate and uterine contraction.


Precipitins to Klebsiella and other enterobacteria in the serum of patients with chronic respiratory disorders.


Arrhythmias and late sudden death after myocardial infarction.


Gastric acid production in jaundice.

Gastric acid production in jaundice.


Epileptic fits as a probable side-effect of amitriptyline. Report of seven cases.


Severe hypothermia as a result of barbiturate overdose complicated by cardiac arrest.


Neuropsychiatric aspects of anticonvulsant megaloblastic anaemia.


How the Scots feed their babies.

How the Scots feed their babies.


Epilepsy and schizophrenia: relationship and biochemistry.


Pharmacology of the carcinoid syndrome.

Pharmacology of the carcinoid syndrome.


Measurement of blood-glucose levels.

Measurement of blood-glucose levels.


Soccer hooliganism.

Soccer hooliganism.


Biochemical profiles and genetic polymorphism.


Alcoholic myopathy.

Alcoholic myopathy.


Ischaemic heart-disease in children.

Ischaemic heart-disease in children.


Infection by anaesthetic apparatus.

Infection by anaesthetic apparatus.


Redeployment of hospital resources.

Redeployment of hospital resources.


Routine measles vaccination in Oxford. Effect on the 1967 epidemic.


Injuries caused by wild animals.

Injuries caused by wild animals.


Results of compression sclerotherapy.

Results of compression sclerotherapy.


Bone-marrow culture in infectious diseases.


Dysgammaglobulinemia type IV.

Dysgammaglobulinemia type IV.


The Aberdeen typhoid epidemic.

The Aberdeen typhoid epidemic.


Paralysis in echovirus-3 infection.

Paralysis in echovirus-3 infection.


Another amitriptyline side-effect?

Another amitriptyline side-effect?


Nucleotide-sugar enzymes in scrapie.

Nucleotide-sugar enzymes in scrapie.


The Coombs test and methyldopa.

The Coombs test and methyldopa.


Settlement of claims of thalidomide families.


Immunopathologic observations in subacute sclerosing panencephalitis.


Production of antibody by the central nervous system in subacute sclerosing panencephalitis.


Subacute sclerosing panencephalitis: brain immunoglobulin-G, measles antibody and albumin.


Treatment of subacute sclerosing panencephalitis with 5-bromo-2-deoxyuridine and pyran copolymer.


Immunologic evidence of measles virus as an etiologic agent in subacute sclerosing panencephalitis.


Light and electron microscopy observations on the development of viral particles in the inclusions of Dawson's encephalitis (subacute sclerosing panencephalitis).


Serological studies of measles and subacute sclerosing panencephalitis.


Lysergic acid diethylamide.

Lysergic acid diethylamide.


Hyperamylasemia from the binding of serum amylase by an 11S IgA globulin.


"Autoimmune" gamma A globulin.

"Autoimmune" gamma A globulin.


The use of 'Hirudoid' cream in general practice.


Treatment of traumatic conditions with 'Hirudoid' cream.


Improving the acceptability of oral continuous progestogens in microdosage for fertility control.


Action of various compounds on the glucose-induced swelling of protoplasts from Streptococcus faecalis.


Electron microscopy of bacteriophage phi R: a comparison of negatively stained and untreated particles.


An assessment of negative staining in the electron microscopy of low molecular weight proteins.


Studies on the pyrogen. IV. Some factors influencing the production of leucocytic pyrogen from polymorphonuclear leucocytes in vitro.


Accelerating effect of Cu++ chelate of kanamycin on oxidation of L-ascorbic acid.


Coexistence of energy-dependent and non-dependent processes in the histamine release mechanism of compound 48-80 and sinomenine: experiments on skin from various animal species.


Effect of anti-lymphocyte serum on responses of human peripheral-blood lymphocytes to specific and non-specific stimulants in vitro.


Cyclic leucocytosis as evidence for retention of normal homoeostatic control in chronic granulocytic leukaemia.


Effect of oral contraceptives on the variations in serum-iron during the menstrual cycle.


Urinary coproporphyrin excretion and hepatic function in women taking oral contraceptives.


effect on performance of reducing blood-alcohol with oral fructose.


Starch-iodic-acid paper in prediciting plasma-thiocyanate concentrations. A possible screening test for chronic cyanide exposure.


Increased resistance developing in Holter valves.


Growth hormone and protein-calorie malnutrition. Impaired suppression during induced hyperglycaemia.


Hypoglycaemia and hyperinsulinaemia in response to raised free-fatty-acid levels.


Masking of antigens on the Landschütz ascites tumour.


Chromosomal aberration in lymphocytes from an extracorporeally irradiated patient.


Oxytocin administration by a variable-speed infusion pump.


Cell substrates for virus vaccines.

Cell substrates for virus vaccines.


Spinal-fluid pH.

Spinal-fluid pH.


A twenty-five-year follow-up of congenital rubella.


Drug dosage for children.

Drug dosage for children.


Aflatoxin content of groundnuts sold for human consumption in Uganda.


Penicillin and orientation.

Penicillin and orientation.


Some aspects of the first recorded case of multiple myeloma.


Paromomycin and Taenia saginata.

Paromomycin and Taenia saginata.


Corticosteroids in aseptic meningitis.

Corticosteroids in aseptic meningitis.


Guanidine in botulism.

Guanidine in botulism.


Treatment of early Hodgkin's disease.

Treatment of early Hodgkin's disease.


Histamine intoxication after cheese.

Histamine intoxication after cheese.


X-ray inactivation of histamine.

X-ray inactivation of histamine.


Hypolipidaemia in anemia.

Hypolipidaemia in anemia.


P.V.P. and platelet adhesiveness.

P.V.P. and platelet adhesiveness.


Infections in heroin addicts.

Infections in heroin addicts.


A comfortable brace.

A comfortable brace.


An Anglo-American cardiovascular comparison.


Measurement and interpretation of hypercalciuria on twenty-four-hour urine series.


Management of complete heart block complicating acute myocardial infarction.


Prognosis of the neurological complications of acute hypernatraemia.


Haemorrhages in posterior-root ganglia in patients dying from head injuries.


Painful sensory disturbance in cervical dermatomes after head injury.


Diagnosis of diarrhoea in general practice. Bacteriological "self-help".


Dextrostix in the diagnosis of neonatal hypoglycaemia.


New antigens in human leukaemic cells and antibody in the serum of leukaemic patients.


Cardiorespiratory comparisons.

Cardiorespiratory comparisons.


Control of heart-rate in healthy young men.


World-wide viruses.

World-wide viruses.


Community-care units and inpatient units as alternatives to the district general hospital.


The case for a national chemical-pathology service.


Signs of heroin usage detected by drug users and their parents.


Postgraduate medical training in Kenya.

Postgraduate medical training in Kenya.


Treatment of tuberculosis overseas.

Treatment of tuberculosis overseas.


Drug rashes in glandular fever.

Drug rashes in glandular fever.


Prophylaxis against tuberculosis.

Prophylaxis against tuberculosis.


Turkey, tryptophan, and psoriasis.

Turkey, tryptophan, and psoriasis.


Combating insecticides in food.

Combating insecticides in food.


Food production in A. D. 2000.

Food production in A. D. 2000.


Lead in drinking water.

Lead in drinking water.


Frusemide renography.

Frusemide renography.


Liver perfusion and blood-pressure.

Liver perfusion and blood-pressure.


Peristalisis and sympathetic activity.

Peristalisis and sympathetic activity.


Loci of human hemoglobin genes.

Loci of human hemoglobin genes.


Silent gene for serum-cholinesterase.

Silent gene for serum-cholinesterase.


Individual satellite-association patterns.


Snowburn.

Snowburn.


Severe respiratory distress in babies.

Severe respiratory distress in babies.


Twins with Klinefelter's syndrome.

Twins with Klinefelter's syndrome.


Antibodies to gastrin.

Antibodies to gastrin.


Microangiopathic hemolytic anemia.

Microangiopathic hemolytic anemia.


Whipple's disease.

Whipple's disease.


The effect of thyroid replacement therapy on the plasma protein bound iodine levels.


Role of gamma globulin for immunoprophylaxis in multiple myeloma.


Sources of error in the determination of phenytoin (Dilantin) by Svensmark & Kristensen's method.


Release of histamine from sensitized rat peritoneal cells by specific and unspecific antigens.


Symposium on research and utilization of educational media for teaching the deaf. Report from captioned films for the deaf.


Symposium on research and utilization of educational media for teaching the deaf. The Instructional Materials Center: a changing concept.


Symposium on research and utilization of educational media for teaching the deaf. Educational Media Center--the Library's new look.


Symposium on research and utilization of educational media for teaching the deaf. Quantitative personnel, materials and equipment standards for audiovisual programs.


Symposium on research and utilization of educational media for teaching the deaf. Media production facilities in schools for the deaf.


Symposium on research and utilization of educational media for teaching the deaf. The idea of the school library and communication.


Symposium on research and utilization of educational media for teaching the deaf. The small school Instructional Materials Center; its diffusion of innovations for learning.


Symposium on research and utilization of educational media for teaching the deaf. Report on library programs in schools for the deaf.


Symposium on research and utilization of educational media for teaching the deaf. Implementing the media program in schools for the deaf.


Symposium on research and utilization of educational media for teaching the deaf. Media personnel at schools for the deaf.


Symposium on research and utilization of educational media for teaching the deaf. In-service education program for teachers of the deaf.


Symposium on research and utilization of educational media for teaching the deaf. The purpose of educational media in the learning process.


Symposium on research and utilization of educational media for teaching the deaf. Symposium discussion summary.


Examination of magnesium binding to serum proteins by ultracentrifugal analysis.


Separation of C'4 from C'1 inactivator and purification of both substances.


Immunoelectrophoretic studies on beta-1-E-globulin in human serum.


Audiovisual systems planning.

Audiovisual systems planning.


A.V. communication, the constant renewal.


Studies in fluorescence histochemistry. II. The demonstration of periodate-reactive mucosubstances with pseudo-Schiff reagents.


Caliban's dream.

Caliban's dream.


The evocation of a genie: a study of an 'as if' character type.


The ampicillin concentration in prostatic tissue and prostatic fluid.


A retional concept of endodontic case presentation.


Improved wound healing with a new intraoral bandage.


Dentists need more drug information.

Dentists need more drug information.


The dental profession and the dental laboratory industry.


Changing trends in health care.

Changing trends in health care.


Cardio-pulmonary resuscitation.

Cardio-pulmonary resuscitation.


Dental school to close; financial burden too great.


Pennsylvania revises curriculum.

Pennsylvania revises curriculum.


Fluoridation and the oral surgeon.

Fluoridation and the oral surgeon.


1967 Annual Award. Presentation address.


The Leon Levy Library.

The Leon Levy Library.


Electrophoresis: application and interpretation.


New treatment program for students.

New treatment program for students.


A profile in dental medicine.

A profile in dental medicine.


The clinical manifestations and treatment of primary and recurrent herpetic infections.


Antrectomy after staining with Congo red and transillumination (Moe's test).


Mucous gland system of the conjunctiva. A quantitative normal anatomical study.


Heterochromatic stabilized images: a classroom demonstration.


Reactivity of human immunoglobulins in echinococcosis and trichinosis.


A general study on the adsorption of protein by tissue.


Studies on low molecular weight peptides derived from human gamma-G-globulin. Identification of rheumatoid factor-reactive peptides in proteolytic digests.


Virus-specific proteins in Escherichia coli infected with some amber mutants of phage MS2.


The composition of human gall-stones.

The composition of human gall-stones.


The ultrastructure of antigen localization and viruslike particles in mouse spleen germinal centers.


Laboratory diagnosis of plague infection.


Assessment of the heterogeneity of reagins according to individuals and/or the kind of allergens.


Properties of two chromatographically distinct reagins in the sera of ragweed atopic individuals.


Transferrin genotypes and their relationship with blood constituents, fertility and cow productivity.


Mechanisms of reflex vasodilation: assessment of the role of neural reuptake of norepinephrine and release of histamine. The mechanisms of reflex vasodilation were studied in an innervated canine hindlimb preparation which was perfused at a constant rate. Reflex vasodilation was produced by suddenly increasing the pressure in the trunk by the intravenous injection of norepinephrine, with consequent stimulation of the baroreceptors. When the basal vasoconstrictor tone exerted by the sympathetic nervous system on the systemic arterial bed was minimized, either by pretreatment with the alpha adrenergic blocking agent phenoxybenzamine or with reserpine, which depletes endogenous catecholamine stores, reflex vasodilation was virtually abolished. Administration of cocaine, a drug which blocks reuptake of norepinephrine by the nerve terminals, significantly reduced reflex vasodilation, the response after cocaine averaging 47% of the vasodilator response in the control period. Cocaine also potentiated the vasoconstriction caused by intra-arterially administered norepinephrine but attenuated the vasoconstriction induced by tyramine. The antihistamine, tripelennamine, had effects similar to those of cocaine. It is suggested, therefore, that reflex vasodilation results from a sudden decrease in the level of norepinephrine at the neuroeffector junction, which is a consequence of the cessation of norepinephrine secretion, together with continued and possibly augmented uptake. When the uptake mechanism is impaired, either by the administration of cocaine or tripelennamine, the magnitude of reflex vasodilation is diminished. It does not appear necessary to postulate active secretion of a vasodilator substance to account for reflex vasodilation.