Antibodies to type III and type VIII pneumococcal polysaccharides: evidence for restricted structural heterogeneity in hyperimmunized rabbits.


Properties of structurally restricted antibody to type VIII pneumococcal polysaccharide.


Specificity of antibody produced in the bullfrog (Rana catesbeiana).


Immunoglobulins of the hamster. I. Antibody activity in four immunoglobulin classes.


Species comparison of antigenic determinants of the variable region of light chains of immunoglobulins.


Immunogenicity of human gamma globulin bound to macrophages after inhibition of RNA synthesis.


Goldfish immunoglobulins and antibodies to bovine serum albumin.


Common antigenic determinants in Fd fragments of guinea pig gamma 1, gamma 2 and gamma M immunoglobulins.


An antigen density effect on the hemolytic efficiency of complement.


Ontogenetic development of C1q synthesis in the piglet.


Thyrotoxicosis: a clinical and laboratory study.


Application of a modified technique to study urinary immunoglobulin light chain and whole IgG excretion in normal human subjects and patients with immune-related disorders.


Research issues in child health. A head start research seminar. 3. Some socio-anthropologic and organizational issues.


In vitro sensitization of rat peritoneal cells by ragweed atopic sera.


Studies on the impulse conducting pathways in the atrium of the mammalian heart.


Mixed papillary and follicular carcinoma of the thyroid gland with stromal amyloid.


Macrophages of the rectal lamina propria in children.


Gangrene of the female breast with anticoagulant therapy: report of two cases.


Laboratory suggestion: a practical stain for routine use with the automatic hematology slide stainer.


Histochemical demonstration of purine nucleoside phosphorylase activity.


Immunological studies on human thyroid glands, especially on antigenicity of epithelial cells in various diseases.


A rapid method for the diagnosis of equine virus abortion. Smears and imprints were made from the liver of 27 equine fetuses, believed to have aborted as a result of Equine Virus Abortion (EVA) infection. Several different fixatives and staining techniques were employed for the demonstration of typical intra-nuclear inclusion bodies in these preparations, and the following conclusions were reached. Methanol proved to be the best fixative and Pappenheim's panoptic method was the best staining technique, giving good contrast and definition of the inclusion bodies. Cytological methods provided a simple and rapid means of diagnosis, but histological sections provided evidence of lesions which was most useful when inclusion bodies were very difficult to find. However, cytological methods proved better than histological sections for the demonstration of EVA intranuclear inclusion bodies.


Basic mechanism of hypersensitivity reactions.


Cardiovascular effects of some phenothiazine derivatives following intracoronary injection in dogs.


Complex effects of antibodies to polypeptide hormones.


Comparison of the metabolic effects of chlormadinone acetate and conventional contraceptive steroids in man.


Thyroid auto-immune disease and thyroid function in families of subjects with Down's syndrome.


Localization of choline acetyltransferase.


Localization of choline acetyltransferase. Ultrastructural localization in spinal neurones.


Infantile metachromatic leukodystrophy.

Infantile metachromatic leukodystrophy.


I-Cell Disease.

I-Cell Disease.


Myocardium stabilization by diphenylhydantoin.


A natural inhibitor of lymphocyte stimulation produced by human thymus.


A new efficient method for preparation of immunoelectrophoretically pure horse antihuman antilymphoblast globulin.


Synergistic effects of cytosine arabinoside combined with antilymphocyte globulin for suppressing xenograft rejection.


Allograft stimulated immunoglobulin synthesis by regional node cells.


The immunologic consequences of lymph lymphocyte depletion.


Medroxyprogesterone antilymphocyte globulin, prednisone, and azathioprine in the treatment of dog renal allografts.


Serum immunoglobulin patterns after burns.


Studies of homograft sex and of gamma globulin phenotypes after orthotopic homotransplantation of the human liver.


Patterns of medical and social research in pediatrics.


Circulating reticulocytes in normal adults as determined y the new methylene blue method.


Dorsal root projections to nucleus cuneatus of the cat.


Immunohistochemistry of glomerulonephritis using horseradish peroxidase and fluorescein-labeled antibody: a comparison of two technics.


The metabolism of different immunoglobulin classes in irradiated mice. 3. Effects of supra-lethal doses of x-rays.


Histochemical and quantitative analysis of muscle biopsies.


Qualitative and quantitative histological study of neuromuscular biopsies from healthy young men.


Lymphocytes: cooperating populations.

Lymphocytes: cooperating populations.


Programmed synthesis and export of immunoglobulin by synchronized myeloma cells.


Evaluation of thyroid function in patients with iodine contamination.


The retention of different plasma proteins in wound tissue.


Effects of different types of oral contraceptives on the protein-bound iodine and the 125I-triiodothyronine uptake on sephadex.


Diagnostic studies of thyroid function. Statistical evaluation of results from the standard radioiodine test and a procedure for fractionation of plasma radioactivity.


Plasma proteins after continuous, oral use of a progestogen--chloromadionone acetate--as a contraceptive.


Genetic polymorphisms in Kenya.

Genetic polymorphisms in Kenya.


Further data on the Gm and Inv allotypes of the Ainu: confirmation of the presence of a Gm2,17,21 phenogroup.


Gamma-globulin for contacts of infectious hepatitis?


An experimental and theoreticl investigation of boundary spreading in gel chromatography.


Oderkerk CH: Isolation and preliminary characterization of corpora amylacea from human brain.


Staining methods and histochemistry of normal gastric mucin.


Histologic staining of contrast-filled blood vessels in microangiographed tissues.


Profile analysis of the oviductal wall in rabbits and cattle.


Biotin deficiency in Arthrobacter globiformis: fine structure and effect of physical stress.


Conidial size and contents in Verticillium as affected by environmental factors.


Detection of latent murine nosematosis and growth of Nosema cuniculi in cell cultures.


'Upper' A-V nodal parasystole.

'Upper' A-V nodal parasystole.


Differential effects in the rat thyroidectomy, propylthiouracil and other goitrogens on plasma insulin and thyroid weight.


Immunoglobulin determinants on the lymphocytes of normal rabbits. I. Demonstration by the mixed antiglobulin reaction of determinants recognized by anti-gamma, anti-mu, anti-Fab and anti-allotype sera, anti-As4 and anti-As6.


Sulphated acid mucopolysaccharide metabolism in the rabbit intervertebral disc.


Antibacterial-agent sensitivity of bacteria isolated from dogs and cats.


Studies of immune mechanisms in leprosy. II Quantitative relationships of IgG, IgA, and IgM immunoglobulins.


Edward Paul Fitton, M.B. Leeds, F.F.A.R.C.S.


John Reginald Alexander Madgwick, M.D. Lond., D.P.M.


Experimental corneal calcificiation: a radioautographic and histochemical study.


Alpha thythm of the electroencephalogram.


An unusual form of diabetes mellitus in ataxia telangiectasia.


Cellular sites of immunologic unresponsiveness. The reconstitution of the immune response of lethally irradiated mice to human gamma-globulin is dependent on the synergistic action of bone marrow with thymus cells. Immunologic unresponsiveness appears to involve a functional defect at each of these cellular levels, inasmuch as neither bone marrow nor thymus cells from unresponsive donors are capable of demonstrating synergism in combination with their normal counterpart.


Heterophile antibodies in mice grafted with syngeneic tumors.


Carcinoma of the esophagus.

Carcinoma of the esophagus.


Structural effects in the action of antibiotics on the ion permeability of lipid bilayers. I. Tyrocidine B.


Transurethral resection of the prostate in patients with cardiac pacemakers.


A cytochemical and ultrastructural analysis of in vitro maturation in amphibian oocytes.


Synthesis of macromolecules in early mouse embryos cultured in vitro: RNA, DNA, and a polysaccharide component.


The development of Ostertagia circumcincta in lambs.


Studies on cryoprecipitation. IV. Enzymic fragments of a human cryoglobulin.


On Cardiofilaria nilesi in experimentally infected chickens with a note on the morphology and periodicity of the microfilariae.


Isolation and characterization of antibodies from sera of humans infected with Echinococcus granulosis.


Some aspects of the pharmacology of oral anticoagulants.


Acridine orange in the staining of blood parasites.


Calcium phosphate in osteogenic cells. A critique of the glyoxal bis(2-hydroxyanil) and the dilute silver acetate methods.


Monthly health specials resource kit.

Monthly health specials resource kit.


Fine structure of the apex of absorptive cell from rat small intestine.


Kinetics of the anticoagulant effect of bishydroxycoumarin in man.


Effect of negative stains used in electron microscopy on some biochemical parameters of the mitochondrial activity.


Primary and secondary response in relation to the initial detection of anti-Rho (D) in Rh-negative mothers at risk.


Booms banned; exhausts exempted.

Booms banned; exhausts exempted.


In pursuit of the Y chromosome.

In pursuit of the Y chromosome.


Blocking of the lymphocyte antigen receptor site with anti-immunoglobulin sera in vitro.


Definitive evidence for the short arm of the Y chromosome associating with the X chromosome during miosis in the human male.


The Y chromosome in human spermatozoa.

The Y chromosome in human spermatozoa.


CAI: technological misconceptions.

CAI: technological misconceptions.


Cones of living amphibian eye: selective staining. The outer segments of cones are selectively stained by the chlortriazinyl dye Procion Yellow injected into the vitreous humor. Since the dye does not cross nerve cell membranes, the selective staining of cones is further evidence for structural differences between rod and cone outer segments. Specifically, it is believed that cone saccules are open to extracellular space whereas rod saccules are not.


Micropunctate fluorescein vital staining of the cornea.


The gonadotropic cells in the adenohypophysis of the blind Mexican cave fish, Anoptichthys jordani.


Alkaline phosphatase activity in the efferent nervous system of the inner ear.


The transsexual boy: mother's feminized phallus.


Whipple's disease: a review of 19 patients from one hospital and a review of the literature since 1950.


Histochemical identification of sulfated and non-sulfated mucopolysaccharides in regenerating forelimbs of adult urodeles.


Sensitization and testing of guinea pigs with potassium bichromate.


Halibut liver poisoning in 11 fishermen.


Neomycin sensitivity in atopic dermatitis and other eczematous conditions.


Fixed drug eruption due to tetracycline.


Aquarium-borne infection with Mycobacterium marinum.


Thalassemia minor and painful ulcers of lower extremities.


Analysis of etiological factors of squamous cell skin cancer of different locations. 2. The trunk and the head.


Disseminated granuloma pyogenicum.

Disseminated granuloma pyogenicum.


Treatment of scleroderma by Rheomacrodex.


Current status of the in vitro sensitivity of gonococci to penicillin in Finland.


Antituberculous treatment of erythema induratum Bazin.


Rolitetracycline by injection and tetracycline phosphate complex by mouth given in a single session in the treatment of gonorrhoea in males.


Gonorrhoea in 1968.

Gonorrhoea in 1968.


Coexistence of lupus erythematosus and scleroderma in light of immunopathological investigations.


Studies on the ultrastructure of keratoacanthoma in man.


The nature of discoid lupus erythematosus.


Blister fluid in bullous pemphigoid.

Blister fluid in bullous pemphigoid.


A study of secondary response in allergic contact sensitivity in the guinea-pig.


Reaming of the medullary cavity and its effect on diaphyseal bone. A fluorochromic, microangiographic and histologic study on the rabbit tibia and dog femur.


Autoradiographic studies on the incorporation of H-uridine into the adrenal glands of mice with spontaneous adrenocortical lipid depletion. A comparison with C57B1 mice.


A cytochemical method for the study of bile canaliculi in fine needle aspirates of the liver.


The ultrastructure of beta cell islet tumour in a dog.


Millipore filter as support for fresh frozen sections of peroral biopsy specimens of small intestine.


Mucosubstances of mixed tumours of the human lacrimal gland. Histochemical and histogenetic aspects.


Fine needle biopsy diagnosis in nodular pulmonary amyloidosis.


A histochemical study of epithelial mucosubstances in endometrial and cervical adenocarcinomas. With reference to normal endometrium and cervical mucosa.


Palliative procedures in congenital heart disease in infants.


The serum alanine aminotransferase activity and the two-hour sulphobromophthalein retention test during daily low-dose gestagen oral contraceptive treatment. Serum alanine aminotransferase activity was measured in 78 women before and after 1-6 months of continuous treatment with .5-mg norethindrone and in 98 women before and after 1-6 months of treatment with .5-mg chlormadinone acetate.  2-hour sulphobromophthalein (BSP) retention was performed on 3 and 11 women taking .4- and .5-mg norethindrone, respectively, and on 19 women taking chlormadinone acetate.  There were no significant differences (p more than .05) between before and after aminotransferase activities.  All BSP retention tests, except for 1 woman who took chlormadinone acetate, were normal.  It is concluded that low doses of norethindrone and chlormadinone acetate have a low tendency to influence liver function as compared with combined oral contraceptives.


A stool survey for enteric organisms in Aspen, Colorado.


Cache Valley virus in the Del Mar Va Peninsula. 3. Serologic evidence for natural infection of dairy cattle.


Electrophoretic analysis of acidic glycosaminoglycans and its application to the developing chick embryo.


Inhibitors of adrenal steroid biosynthesis.


Studies on cytochrome oxidase. II. Ultrastructure of cytochrome oxidase.


Persisting human blastocysts. A preliminary report.


The human serum immunoglobulins.

The human serum immunoglobulins.


Serum lactate dehydrogenase isoenzyme changes in carcinoma of the prostate.


The effect of muscle relaxants on peripheral blood flow.


Surgical treatment of esophageal carcinoma.


Transcription and translation in the lactose operon of Escherichia coli studied by in vivo kinetics.


Evaluation of the "prostate test" in checking the administration of oestrogens in the calf.


Modified tecnique of muscle biopsy.

Modified tecnique of muscle biopsy.


Combined staining of alcian green and picro-fuchsin for the investigation of regenerative enchondral ossification (callus formation).


Historadiographic study of exfoliated cells of the oral mucosa. A method for comparison of historadiograms and Papanicolaou staining.


A selective method for the isolation of Haemophilus in material from the respiratory tract.


Immunochemical studies of oral fusobacteria. 6. Distribution of a group reactive antigen among some bacteria and occurrence of antibodies in human sera to this antigen.


Transmission of Toxoplasma gondii. Further studies on the morphology of the cystic form in cat faeces.


Dikaryotic fruiting in Schizophyllum commune fr.: morphology of the developing basidiocarp.


ctothiorhodospira halophila: a new species ofthe genus Ectothiorhodospira.


Relationship of thermal environment and caloric intake to growth and resting metabolism in the late neonatal period.


Inclusions in terminal air spaces of fetal and neonatal human lung.


Immunoglobulin levels and gestational age.


Inhibiting effect of actinomycin C on the appearance of delayed hypersensitivity in guinea pigs.


Behavior of Leishmania in Panamanian phlebotomine sandflies fed on infected animals.


Radiation dose effects in relation to obstetric x-rays and childhood cancers.


Wound infection with Pseudomonas multivorans. A water-borne contaminant of disinfectant solutions.


Skin-reactive soluble antigen from intestinal cancer-cell-membranes and relationship to carcinoembryonic antigens.


Suprapubic aspiration of urine in diagnosis of urinary-tract infections during pregnancy.


Antigen-binding lymphocytes in human fetal thymus.


Serum immunosuppressive activity due to azathioprine and its relation to hepatic function after liver transplantation.


Hexachlorophane for treating carriers of Staphylococcus aureus.


Epsilon-aminocaproic acid in preoperative correction of haemostatic defect in cyanotic congenital heart-disease.


Viruses in the treatment of cancer.

Viruses in the treatment of cancer.


Plasma-insulin in diabetes.

Plasma-insulin in diabetes.


Training of anaesthetists.

Training of anaesthetists.


The work of W.H.O.

The work of W.H.O.


Diphtheria.

Diphtheria.


Standardisation of heparin.

Standardisation of heparin.


Pollution.

Pollution.


Another pseudomonas.

Another pseudomonas.


A matter of weeks.

A matter of weeks.


Psychiatric day hospital and community.

Psychiatric day hospital and community.


Brucellosis and the British public.

Brucellosis and the British public.


Diphtheria today. Some experiences in Iran.


Plight of E.E.G. technicians.

Plight of E.E.G. technicians.


Medical care in North Vietnam.

Medical care in North Vietnam.


Arrhythmias during acute myocardial hypoxia.


Neurological complications of tuberculosis.


Kidney preservation.

Kidney preservation.


Organ exchange and tissue typing.

Organ exchange and tissue typing.


The Veterans Administration.

The Veterans Administration.


Contamination of blood stored in plastic packs.


The recurrent laryngeal nerves at thyroidectomy.


Bone pain from tumours.

Bone pain from tumours.


L-tryptophan in depression.

L-tryptophan in depression.


The errors of medicine.

The errors of medicine.


Sex ratio in phenylketonuria.

Sex ratio in phenylketonuria.


Rabies vaccines.

Rabies vaccines.


Prevention of leucocyte-antibody formation.


Gene-frequencies in Jews.

Gene-frequencies in Jews.


Effects of L-dopa in patients with dementia.


L-dopa with MK 485 for depression.

L-dopa with MK 485 for depression.


Use of test strips with colour meter to measure blood-glucose.


L-dopa and non-emission of semen.

L-dopa and non-emission of semen.


Inflation in the laboratory.

Inflation in the laboratory.


Topical treatment of burns.

Topical treatment of burns.


Lithium in pregnancy.

Lithium in pregnancy.


Crossed lines.

Crossed lines.


Antibiotics in surgical treatment of septic lesions.


The distending force in the production of communicating syringomyelia.


Significance of HL-A cytotoxic antibodies in Rh haemolytic disease.


Alpha rhythm: an artefact?

Alpha rhythm: an artefact?


L-asparaginase and blastogenesis.

L-asparaginase and blastogenesis.


Dermatoglyphics in children with leukaemia.


William Alexander Low M.C., M.B. Lond., F.F.A. R.C.S.


Nuala Crowley L.R.C.P., F.R.C.Path.

Nuala Crowley L.R.C.P., F.R.C.Path.


Clinical trials of application of paired pulse stimulation in heart failure after cardiac surgery.


Cross-reactivity and antigenic structure of the C 5 component of human complement.


Serum immunoelectrophoresis in myocardial infarction.


Skin tests in patients with chronic disseminated lupus erythematosus with particular consideration of tests with so-called nuclear factors.


Medical grand rounds from the University of Alabama Medical Center.


Adverse responses due to allergy and drug interactions during otorhinolaryngologic procedures.


The treatment of thyroid crisis.

The treatment of thyroid crisis.


The embryolethality and localization of antikidney serum in the pregnant mouse, Mus musculus.


A postulated mechanism for the insulin synergistic and insulin antagonistic action of growth hormone.


States of immune deficiency.

States of immune deficiency.


The response of ponies to Myxovirus influenzae A-equi 2. II. Immunoglobulin classes of antibody to the virus in serum and nasal secretions. Nasal secretions and serum were collected from ponies in order to determine the types of immunoglobulins responsible for antibody activity against Myxovirus influenzae A-equi 2. Using specific antisera to remove each immunoglobulin, the antiviral activity of serum was shown to be a property of IgG globulin, whereas in nasal secretions activity was found in both IgG and IgG(T) globulins. However in secretions the predominant activity was attributed to IgG(T) globulin. Because of its sensitivity to 2 mercaptoethanol, early serum antibody was assumed to belong to the IgM class of immunoglobulins. From its behaviour in sucrose density gradients and on Sephadex G 200 columns, the antibody in nasal secretions was assumed to be of 7S mobility not 11S such as is found in man.


Evidence for a mutational event at the B blood group-histocompatibility locus in chickens.


Immunoglobulin production and allograft rejection in the fetal lamb.


Prognosis in Hodgkin's disease with special reference to histologic type. Results of treatment predominantly by cytostatics.


The structure of Uukuniemi virus.

The structure of Uukuniemi virus.


6-Azauridine as an inhibitor of the synthesis of Herpesvirus hominis.


Multiplication of Tribec arbovirus in L cells.


Some physical and chemical properties of Kemerovo virus; a comparison with group A and B arboviruses.


Fluorescence and ultrastructural features of amine-storing cells in the human gastric mucosa.


Corpora amylacea--probable modal relationship to alveolar septal cells.


Immunoglobulins with activity of rheumatoid factor in patients with ulcerative colitis.


Search of quick method of contrast staining of Trichinella spiralis larvae in muscles.


The importance of the biopsy in the diagnosis of the Trichinella spiralis infection.


Selective staining of the ultra-structural components of cortical granules and golgi cisternae of sea urchin eggs.


Occurrence of the neurosecretory substance during the embryonic development of the guinea pig.


Separation of ECHO virus type 6 antigens by centrifugation in caesium chloride density gradients. I. Infectivity and antigenic activities.


Morphological changes in nuclei of BSC-1 cells infected with measles virus.


Interaction between SV 40 and other viruses in tissue culture: interference and double infection.


Electron optical studies of bovine viral diarrhea-mucosal disease virus (BVDV).


Immunofluorescent localization of toxoplasma antigens in the salivary glands of rats during infection with Toxoplasma gondii.


Axonal reaction of the optic nerve following heat coagulation. Histochemical evidence for antidromic convection.


A population study on serum immunoglobulin levels.


The cross striation pattern of the fibrin fibril.


The occurrence of serum 7S IgM in diseases associated with immunoglobulin abnormalities.


Reaginic antibody in adult and young mice. Production and biological properties.


Immunochemical studies of selected subjects with wheat intolerance.


The potency and antigen E content of commercially prepared ragweed extracts.


Inclusion bodies and tubular structures in Chenopodium amaranticolor plants infected with strawberry latent ringspot virus.


Electron microscopy of the RNA of foot-and-mouth disease virus.


Dissection of vesicular stomatitis virus into the infective ribonucleoprotein and immunizing components.


Direct cell to cell transfer of Bittner virus.


Congenital goitre and hypothyroidism produced by maternal ingestion of iodides.


Chronic liver disease and primary liver-cell cancer with hepatitis-associated (Australia) antigen in serum.


Urinary protein excretion in climbers at high altitudes.


The painful deep-vein syndrome.

The painful deep-vein syndrome.


Hereditary blindness among Pingelapese people of Eastern Caroline Islands.


ABO blood-groups and venous thromboembolic disease.


Lymphocyte abnormality in chronic mucocutaneous candidiasis.


No cue for passion.

No cue for passion.


Spread of Hodgkin's disease.

Spread of Hodgkin's disease.


Routine smallpox vaccination: a dilemma.


Health in the Third World.

Health in the Third World.


Treatment of phenylketonuria.

Treatment of phenylketonuria.


Skeletal tuberculosis.

Skeletal tuberculosis.


Dangers of iodides in pregnancy.

Dangers of iodides in pregnancy.


Thoracic-duct drainage in renal transplantation.


ABC of endocrinology. V. Adrenal cortex.


Paediatrics and the district general hospital.


Cholera.

Cholera.


Battered babies--how many do we miss?

Battered babies--how many do we miss?


Effect of corticotrophin on plasma-growth-hormone.


Circulating heparin-like substance after liver injury.


Determination of death.

Determination of death.


Oral contraceptives, depression, and aminoacid metabolism.


Malignant hyperpyrexia.

Malignant hyperpyrexia.


Deformities in a child whose mother took L.S.D.


Dexamphetamine: a possible environmental trigger in cardiovascular malformations.


Septo-optic dysplasia.

Septo-optic dysplasia.


Methohexitone for phobias.

Methohexitone for phobias.


Influence of age on alpha-fetoprotein incidence.


Psychogeriatric assessment units.

Psychogeriatric assessment units.


Gastrointestinal bleeding.

Gastrointestinal bleeding.


The duration of pregnancy.

The duration of pregnancy.


Nucleated red-cells in the newborn.

Nucleated red-cells in the newborn.


Treatment of congenital thymic aplasia by graft of fetal thymus.


Zinc in psoriasis.

Zinc in psoriasis.


Mycoplasma and the urogenital tract.

Mycoplasma and the urogenital tract.


Immunopathology of acute leukemia in childhood.


A new histophysiological concept of the striated tubules based on a very simple and new method for staining of mitochondria.


Effects of glacial acetic acid on the extraction, chemical stability, and biological activities of beta-LPH.


The serum immunoglobulin level in Down's syndrome.


Effect of methanol on exhaust composition of a fuel containing toluene, n-heptane, and isooctane.


The addition of cava pulmonary artery shunts to patients with existing systemic pulmonary artery shunts.


Complete heart block complicating hyperthyroidism.


The role of immunoglulins in the mechanism of mucosal immunity to virus infection.


Hypergammaglobulinemia in swine infected with African swine fever virus.


Effects of freezing on marrow stem cell suspensions: interactions of cooling and warming rates in the presence of PVP, sucrose, or glycerol.


Factors affecting the binding of retinol to serum and its components.


Intraphagosomal pH of human polymorphonuclear neutrophils.


Serum complement in acute bronchiolitis.


Labelling nuclei of progressively developing pollen mother cells and pollen with tritiated thymidine in Tradescantia.


Evaluation of pollen viability by enzymatically induced fluorescence; intracellular hydrolysis of fluorescein diacetate.


A simple method to demonstrate lipids in epon-embedded ultrathin sections.


Selective skeletal staining in whole chicken embryos; a rapid Alcian blue technique.


Histochemical localization in animal tissues of a special peroxidase which generates the free radical of ascorbic acid.


In vitro, cell protective effects by certain antiproteases of human serum.


Studies on closure of the ductus arteriosus. V. Microradiographical observations with ultrasoft x-rays on closure of the ductus arteriosus in the rat and the guinea-pig.


Arteriolar permeability and destruction of elastic membrane in hypertension.


Effects of simultaneous thyroidectomy and oestrone treatment on the pituitary cytology in the mouse. A light and electron microscopic study.


The intrarenal vascular alterations in experimental chronic pyelonephritis and their relationship to the development of hypertension.


Anatomical injections.

Anatomical injections.


Biochemical and histochemical localization of invertase in Neurospora crassa during conidial germination and hyphal growth. The intracellular localization of Neurospora invertase, an enzyme partially secreted and partially retained by Neurospora at the cell periphery, was investigated. A cell wall fraction was isolated, to which 24% of the cell-bound invertase was firmly attached. A sensitive osmiophilic stain for invertase was developed and used in conjunction with the technique of indirect immunofluorescence to follow the pattern of invertase localization during the development of Neurospora from the germination of conidia to the mature hypha. These studies revealed that: (i) conidial invertase was uniformly distributed along the cell periphery; (ii) growing hyphal tips of germinating conidia showed pronounced invertase activity as the rest of the conidial cell wall lost its peripheral activity; (iii) hyphae in early log-phase growth had strong enzyme activity associated with the cell wall, and in late log phase the activity became associated with the plasma membrane and points where new hyphal branches were being formed; and (iv) hyphae in early stationary phase had strong fluorescence at incipient branching points, in "dots" close to the plasma membrane, and in the cytoplasm.


Ultrastructure of Mycoplasma laidlawii during culture development. Mycoplasma laidlawii B has been studied by phase-contrast and electron microscopy (thin-section and negative staining). Exponential-phase cells are filaments with the following structures: surface unit membrane, nuclear material, ribosomes, and intracellular granular region. These cells appear to reproduce by binary fission. In stationary phase, the filamentous cells have numerous constrictions, giving them a beaded appearance. Nonviable death-phase cultures contain cellular debris: swollen cells, granular bodies, and other aberrant forms.


Association of the crystalline inclusion of Bacillus thuringiensis with the exosporium. Thin sections of sporulating cells of Bacillus thuringiensis show a marked association between the crystalline inclusion and the exosporium.


Immunological memory in mice. I. Physical separation and partial characterization of memory cells for different immunoglobulin classes from each other and from antibody-producing cells. Plaque forming cells (PFC) of different immunoglobulin classes producing antibodies against sheep erythrocytes were separated according to their buoyant densities by means of equilibrium centrifugation in a stepwise BSA gradient. In the period of 7-10 days after immunization gammaM PFC are markedly enriched in fractions of low density and relatively depleted in fractions of high density. The distribution of total gammaG PFC shows less enrichment in the lower density fractions and less depletion in the higher density fractions. The density profile for gammaG(2a) PFC is even flatter, with a significant difference (depletion) relative to the unseparated spleen cells only in the highest density fraction. The density gradient distributions of cells able to transfer an adoptive immune response of the various immunoglobulin classes are markedly different from the PFC distribution. Cells obtained 7-10 days after immunization able to transfer an IgM response are present in the same proportions across the density gradient, whereas memory cells for gammaG(2a) obtained at this time are markedly enriched in fractions of low density and virtually depleted from high density fractions. With increasing time after primary immunization, the gammaG(2a) memory cells increase progressively in density and by 6 weeks the higher and lower density fractions have the same proportions of gammaG(2a) memory cells. The total gammaG (mainly gammaG(1)) memory cells by 7-10 days show slight enrichment in low density fractions and no depletion in high density fractions. The conclusions were reached that (a) memory for gammaG(1) develops earlier than memory for gammaG(2a) and (b) that memory for anti-SRBC antibodies of different classes is carried in separate cells. When gradient fractions enriched for PFC and memory cells for all classes were completely depleted of PFC using glass bead columns, the ability of this fraction to transfer memory for all classes was not diminished. This shows that memory cells are not identical with cells secreting antibodies.


Immunological memory in mice. II. Cell interactions in the secondary immune response studies by means of immunoglobulin allotype markers. Congenic mice, differing genetically only at the loci coding for immunoglobulin H chain (or Fc) structures, have been used to study cell interactions in the 7S (gammaG(2a)) antibody response to sheep erythrocytes (SRBC), as detected by the Jerne plaque-forming cell (PFC) method. The interaction between thymus and bone marrow cells was studied in adult thymectomized irradiated recipients, protected with syngeneic bone marrow and injected with thymus cells from the partner congenic strain. All of the gammaG(2a) PFC detected in the spleens of these mice were of bone marrow allotype. Adoptive secondary immune responses were then studied to determine whether a similar interaction between memory cells and bone marrow derived cells could be detected. Primed spleen cells from the partner congenic strain, or a subpopulation of these cells obtained by BSA density gradient fractionation, were injected into irradiated recipients alone, or together with syngeneic nonimmune spleen or bone marrow cells. All gammaG(2a) PFC detected in these experiments were of primed cell allotype. There was no evidence that antibody forming cell precursors in normal spleen or bone marrow participate in the adoptive secondary immune response detected 7 days after transfer of primed spleen cells. This was true regardless of whether the bone marrow cells were injected at the time of transfer, or were injected 1-2 wk earlier and allowed to become established in the spleens of recipient mice. Although no specific cell interaction was seen, bone marrow (and, to a lesser degree, normal spleen) cells were found to have a nonspecific enhancing effect on the adoptive secondary response when they were injected together with the primed spleen cells. This enhancement was not evident if the bone marrow cells were injected 1 or 2 wk prior to primed cell transfer.


The emergence of antibodies with either identical or unrelated individual antigenic specificity during repeated immunizations with streptococcal vaccines. Electrophoretically monodisperse antibody components in rabbit antisera to the carbohydrates of the Groups A and C streptococci have been examined for their individual antigenic specificity. In these antibody components which were isolated by preparative electrophoresis, individual antigenic specificity was confined to the specific antibody and was absent in the nonantibody gamma-globulin. Radioprecipitation experiments and the use of immune absorbent columns constructed from goat anti-antisera, which had been absorbed with fraction II, revealed that all the specific antibody in an electrophoretically monodisperse component was reactive with the homologous anti-antibody. Antibodies with either identical or distinct individual antigenic specificities may occur in the same rabbit with repeated immunizations. Antibodies with identical antigenic specificity had identical electrophoretic mobility, whereas antibodies with unrelated antigenic specificities had distinct electrophoretic mobilities. In the interval between immunizations, if antibody to the carbohydrate antigen was absent, there was no detectable antibody with individual antigenic specificity.


Induction of immunologic tolerance in older New Zealand mice repopulated with young spleen, bone marrow, or thymus. Newborn, 7-9 day, and 16-18 day old NZB and B/W mice were, unlike older New Zealand mice, rendered tolerant to single doses of 8-10 mg of soluble BGG. After challenge, this tolerance was of short duration and escape occurred rapidly. Age-matched and similarly treated C3H, Balb/c and C57Bl mice did not escape from tolerance. Partial tolerance could be maintained by repeated injections of BGG. Biofiltration ruled out hyperphagocytosis as an explanation for this resistance to tolerance. Tolerance could be induced in older B/W mice if they were thymectomized, irradiated, and repopulated with young (12-15 day), but not old (2-3 month), spleen or bone marrow cells. Old bone marrow cells gave a non-tolerant response even when combined with young thymic grafts. Young bone marrow gave a tolerant response which was followed by the expected rapid escape only if a young thymus graft was also present. Escape was retarded if old thymus, or old irradiated thymus, was combined with young bone marrow. These results are best explained by abnormalities of both lymphoid precursors and thymic regulation.


Characteristics of a non-complement-dependent C3-reactive complex formed form factors in nephritic and normal serum. When serum from a patient with membrano-proliferative glomerulonephritis and normal serum are mixed at 37 degrees C, C3 is rapidly broken down to two more rapidly migrating components. In the mixture, a heat-labile pseudoglobulin, designated as the C3 nephritic factor or C3NeF, reacts with a pseudogolbulin in the normal serum, designated as cofactor, to form a C3 inactivator. By analogy with the cobra venom factor, the C3 inactivator is most likely a complex of the nephritic factor and cofactor. The complex has been designated as the C3 lytic nephritic factor or C3LyNeF. The reaction which results in the Formation of C3LyNeF requires the presence of Mg(++), is highly temperature sensitive but occurs very rapidly at 37 degrees C. In 20 min at 37 degrees C, C3LyNeF can break down over 80% of the C3 in a mixture of normal and nephritic serum. The two-step reaction which leads to C3 breakdown has an optimum pH ranging from 6.0 to 9.0. Experiments employing serum depleted of C4 and C2, as well as certain characteristics of the C3NeF system provide evidence that C3 breakdown with nephritic serum is not dependent on complement-inactivating immune complexes or on the action of convertase (C4, 2). Data relating rate of C3 breakdown to the concentrations of C3NeF, C3, and C3LyNeF in the reaction mixture are similar to those for the reaction of enzyme with substrate. The biological significance of C3LyNeF in the production of glomerular inflammation has not been established.


Immunochemical relationships of certain capsular polysaccharides of Klebsiella, pneumococci and Rhizobia.


Antigenic release of histamine from rabbit leukocytes.


Some observations on the phylogeny of serum inhibitor of C1 esterase.


Studies on tetanus antitoxin. I. Isolation of two neutralizing antibodies from tetanus antitoxin.


Repression of the synthesis of immunoglobulins in newborn mice by antibodies directed against the variable region of light chains.


The second reported kindred with hereditary resistance to oral anticoagulant drugs.


Human dentinogenesis with special regard to the formation of peri-tubular crown dentine and zones in fetal deciduous and unabraded permanent teeth. A morphologic, microradiographic and histochemic study.


Toxicological studies on beryllium oxides and beryllium-containing exhaust products. AMRL-TR-68-148.


A cardiac vector indicator.

A cardiac vector indicator.


Results of palliative procedures for tetralogy of Fallot in infants and young children.


Selection of palliative procedures in transposition of the great vessels.


Clinical trial on a new combination of hepatoprotecting agents.


Histochemistry of a cotylocercous cercaria. I. Glandular complex in Plagioporus lepomis.


Toxoplasma: seroreactions with antibody fragments.


Trypanosoma cruzi: preference for brown adipose tissue in mice by the Tulahuen strain.


Ascaris suum and Toxocara canis: radioautographic detection of DNA in Feulgen-Negative muscle nuclei.


A PAS reaction in erythrocytes of formalin-fixed tissue treated with Holt's hypertonic gum sucrose.


Histochemical investigations on the nature of large blood vessel endothelial and medial argyrophilic lines and on the mechanism of silver staining.


Digitonin reaction in electron microscopy.


Effect of exercise on skeletal muscle. I. Biochemical and histochemical properties.


Permeability of human and rat dental calculus.


Reflex sympathetic dystrophy. Review of 140 cases.


Effect of hypophysectomy, adrenalectomy, and thyroidectomy on the beta--cells of the islets of Langerhans of the pancreas.


Effect of salicylate treatment on fetal and maternal prothrombin time in the mouse.


Ultrastructural studies with influenza viruses. I. Effect of some reagents on the fine structure of the virion.


Nature of iodinated substances released onto the paper strip from in vivo 131I-labelled whole rat thyroid lobes during electrophoresis.


Correlation of renal blood-flow indices and histamine metabolism after canine renal allografting.


The function of ubiquinone in Escherichia coli. 1. The function of ubiquinone in Escherichia coli was studied by using whole cells and membrane preparations of normal E. coli and of a mutant lacking ubiquinone. 2. The mutant lacking ubiquinone, strain AN59 (Ubi(-)), when grown under aerobic conditions, gave an anaerobic type of growth yield and produced large quantities of lactic acid, indicating that ubiquinone plays a vital role in electron transport. 3. NADH and lactate oxidase activities in membranes from strain AN59 (Ubi(-)) were greatly impaired and activity was restored by the addition of ubiquinone (Q-1). 4. Comparison of the percentage reduction of flavin, cytochrome b(1) and cytochrome a(2) in the aerobic steady state in membranes from the normal strain (AN62) and strain AN59 (Ubi(-)) and the effect of respiratory inhibitors on these percentages in membranes from strain AN62 suggest that ubiquinone functions at more than one site in the electron-transport chain. 5. Membranes from strain AN62, in the absence of substrate, showed an electron-spin-resonance signal attributed to ubisemiquinone. The amount of reduced ubiquinone (50%) found after rapid solvent extraction is consistent with the existence of ubiquinone in membranes as a stabilized ubisemiquinone. 6. The effects of piericidin A on membranes from strain AN62 suggest that this inhibitor acts at the ubiquinone sites: thus inhibition of electron transport is reversed by ubiquinone (Q-1); the aerobic steady-state oxidation-reduction levels of flavins and cytochrome b(1) in the presence of the inhibitor are raised to values approximating those found in the membranes of strain AN59 (Ubi(-)); the inhibitor rapidly eliminates the electron-spin-resonance signal attributed to ubisemiquinone and allows slow oxidation of endogenous ubiquinol in the absence of substrate and prevents reduction of ubiquinone in the presence of substrate. It is concluded that piericidin A separates ubiquinone from the remainder of the electron-transport chain. 7. A scheme is proposed in which ubisemiquinone, complexed to an electron carrier, functions in at least two positions in the electron-transport sequence.


Light and electron microscope studies on the conidium and germ tube of Sphaerotheca macularis.


Microorganisms in soil as observed by staining with rhodamine-labeled lysozyme.


Inhibition of cell division in Micrococcus lysodeikticus dis-II.


The normal range and determinants of the intrinsic heart rate in man.


Simultaneous demonstration of adrenergic and non-adrenergic nerve fibres.


A silver-impregnation-toluidine blue technique for demonstration of embryonic skeletal structures in paraffin sections.


The occurrence of neutral and acidic mucins in the reproductive tract of the laying hen.


A modified azo-dye method for identification of seminal stains.


Hapten-carrier relationships of isoantigens. A model for immunological maturation based on the conversion of haptens of carriers by antibody. In chickens, erythrocyte isoantigens have hapten-carrier relationships. Specific anticarrier antibody depresses the immune response to the carrier and enhances the immune response to the hapten. Antigenic determinants of "haptenic" isoantigens behave as carriers if they are coated with specific antibody. It is postulated that every humoral antibody response involves the cooperation of a carrier with a hapten and the progressive conversion by antibody of haptens to carriers. Thus a carrier is viewed as an antigenic determinant which is coated with antibody. The antibody-forming cell only synthesizes antibody to the uncoated haptenic determinants. The consequences of this interpretation for the development of immunological maturity and the secondary immune response are discussed.


Myxoedema in pregnancy.

Myxoedema in pregnancy.


Myxoedema and pregnancy. A case report.

Myxoedema and pregnancy. A case report.


The value of the Nile blue test in estimating fetal maturity in normal and complicated pregnancies.


The use of sodium amino hippurate as an alternative to Coomassie Blue to determine amniotic fluid volume.


Concentration of IgE immunoglobulin in serum of children and its clinical significance.


[Histologic study of polyanions of mast cells using the method of critical electrolyte concentration].


Immunoglobulins in protein-calorie malnutrition.


The biosynthesis of 4-hydroxycoumarin and dicoumarol by Aspergillus fumigatus Fresenius. A strain of Aspergillus fumigatus Fresenius, isolated from spoiled hay, converts melilotic acid (o-hydroxyphenylpropionic acid) and o-coumaric acid into 4-hydroxycoumarin and dicoumarol. The sequence is shown to be melilotic acid (I) [Formula: see text] coumaric acid (IV) [Formula: see text] beta-hydroxymelilotic acid (II) [Formula: see text] beta-oxomelilotic acid (III) [Formula: see text] 4-hydroxycoumarin (VI), on the basis of (1) studies on the formation of postulated intermediates, (2) experiments with isotopically labelled materials and (3) sequential enzyme induction. In the presence of semicarbazide, o-coumaraldehyde is formed from o-coumaric acid: there is no evidence, however, that this lies on the normal metabolic pathway.


The effect of experimental cardiac arrhythmias of a new anticonvulsant agent, Kö 1173, and its comparison with phenytoin and procainamide.


The inhibition of allergic reactions by sympathomimetic amines and methylxanthines.


Propranolol and radioactive iodine in the treatment of thyrotoxicosis.


Trial of etorphine hydrochloride(M99 Reckitt) in carcinoma pain: preliminary report.


Pathology of diabetic retinopathy.

Pathology of diabetic retinopathy.


Chlordiazepoxide (Librium) and tests of thyroid function. The effect of chlordiazepoxide (Librium) on thyroid function was examined in 14 euthyroid patients who required the drug for psychiatric reasons and in six patients with clinically mild thyrotoxicosis. There was no significant difference in results from tests of thyroid iodide trapping (thyroid radioiodine uptake, thyroid clearance, and absolute iodine uptake) or of thyroid hormone release (protein-bound iodine, T3 resin uptake, and free thyroxine index) carried out before and during treatment with the drug over a four-week period. It is suggested that chlordiazepoxide need not be withdrawn before thyroid status and function are assessed in any patient taking the drug.


Prophylaxis against rubella and mumps.

Prophylaxis against rubella and mumps.


Local immunity and persistence of virus in the tracheas of chickens following infection with Newcastle disease virus. I. Organ culture studies.


Local immunity and persistence of virus in the tracheas of chickens following infection with Newcastle Disease Virus. II. Immunofluorescent and histopathologic studies.


Some physical, chemical, and taxonomic features of the soluble antigens of the Brucellae.


Fibrinogen recovery in fibrinolytic dogs. Influence of vitamin K.


Platelet reactions and immune processes. 3. The inhibition of platelet aggregation by chymotrypsin substrates and inhibitors.


Dental illustration: a growing area.

Dental illustration: a growing area.


The progressive development of visual learning aids in oral surgery.


Hepatic composition and metabolism after ethanol consumption in rats fed liquid purified diets.


Biophysical and biochemical characterization of lymphocytic choriomeningitis virus. IV. Strain differences. Biological, biochemical, and biophysical properties of three lymphocytic choriomeningitis (LCM) virus strains were compared. The biological property examined was the concentration range of virus which would, when injected into neonates, cause a carrier state. The dosage range for the CA1371 and Traub strains was found to be as broad as the limits examined (5 to 100 ld(50) units/mouse). The WCP strain, however, would only produce carriers within a 3 to 5 ld(50) range. The biochemical properties examined were the growth rates in tissue culture and the effect of varying the input ratio of virus to cells. With identical input ratios, the Traub strain reached a peak titer 32 hr after infection. The CA1371 and WCP strain reached their peaks at the 40th hr. With a 10-fold decrease in the amount of CA1371 virus per cell, peak titer (as high as in the above experiments) was not obtained until 56 hr postinfection. The biophysical properties examined were stability in density gradients and inactivation rates at 4C. In potassium tartrate gradients, full recovery of the CA1371 and WCP strain could be achieved. However, inactivation kinetics showed that only the CA1371 strain was much more stable than the Traub-LCM. The realization that marked differences in LCM strains exist is discussed in relation to certain inconsistencies in the literature.


Schizophrenia, an immunologic disorder?

Schizophrenia, an immunologic disorder?


Chi-square significances.

Chi-square significances.


Care of the mentally subnormal.

Care of the mentally subnormal.


Electron microscopical evaluation of the osmic acid-zinc iodide nerve staining technique (method of Champy-Maillet) on pulmonary tissue.


Occurrence and ultrastructure of lipid droplets in the developing chick intestinal epithelium.


The circulating immunoglobulins involved in protective immunity to the intestinal stage of Nippostrongylus brasiliensis in the rat.


Studies on "allergoids" prepared from naturally occurring allergens. I. Assay of allergenicity and antigenicity of formalinized rye group I component.


Immune injury of mouse peritoneal mast cells by antibodies to mouse serum and mouse gamma-globulin.


Some normal values of thyroid function in horses.


Mucopolysaccharide in the blood of a patient with neuroblastoma. In a case of neuroblastoma the presence of an abnormal blood constituent was suspected from the raised erythrocyte sedimentation rate, sludging of the red cells, marked rouleaux formation, an atypical Leishman stain, increased plasma viscosity, and a distorted protein electrophoresis pattern. The abnormal constituent was shown to be a mucopolysaccharide which was either hyaluronic acid or chondroitin sulphate.


Immunoglobulin levels in normal pregnancy and pregnancy complicated by hypertension.


Histochemical and autoradiographic investigation of the serous cells of the human bronchial glands.


Long-term plasma infusions in a patient with ataxia-telangiectasia and deficient IGA and IGE.


Peripheral neuropathy. Changing concepts, differential diagnosis and classification.


Tracheobronchiomegaly and acquired cutis laxa in a child. Physiologic and immunologic studies.


Urine screening for disorders of mucopolysaccharide metabolism.


Chemical components and mode of hardening of the cuticle of Collembola.


The histochemical specificity of mucicarmine staining in the identification of epithelial mucosubstances.


A histochemical study of epidermal mucous secretions in Enteropneusta (Hemichordata).


Radiotelemetry of phasic right ventricular blood velocity in man.


The effect of glucagon on arrhythmias due to digitalis toxicity.


Inoculation of animals with anti-D immunoglobulin used for prophylaxis of hemolytic disease of the newborn. I. Titers of immune antiglobulin antibodies in the blood serum of rabbits inoculated with human anti-D immunoglobulin used in serologic incompatibility in the Rh system.


Quantitative evaluation of immunoglobulins in the serum of patients with hepatic cirrhosis.


The immunologic response of AKR mice in different phases of development of transplanted gross leukemia.


The radiomimetic effect of actinomycin C on tumors of glial origin cultured in vitro.


Human immunoglobulin subclasses. Partial amino acid sequence of the constant region of a gamma 4 chain. The heavy chain of a human myeloma protein (Vin) belonging to the gamma4 subclass was subjected to tryptic digestion after reduction and carboxymethylation. Cyanogen bromide fragments were also prepared and all 19 tryptic peptides that account for one of them (the Fc-like fragment) were studied. Selected peptic peptides were isolated and provided evidence for the order of 15 of the tryptic peptides. In addition the sequence of two large peptic peptides derived from two sections of the molecule including all the interchain bridges is presented. Comparison with published data on other chains allows us to propose a sequence of gamma4 chains that extends from just before the presumed starting point of the invariable region (at about residue 113) to the C-terminal end of the chain (approx. residue 446), except for a section of about 50 residues. The results of the comparison suggest that the immunoglobulin subclasses have a recent independent evolutionary origin in different species. Implications for complement fixation and for the evolutionary origin of antibody diversity are also discussed.


Organization of mitochondrial structure as revealed by freeze-etching.


The air we breathe.

The air we breathe.


Specificity of antibodies in single cells after immunization with antigens bearing several antigenic determinants. Study with a new paired staining technique.


Immune complexes in rheumatoid synovitis: a mixed staining immunofluorescence study.


Squamous cell carcinoma of the bladder.

Squamous cell carcinoma of the bladder.


Changes in the blood-testis barrier of the guinea-pig in relation to histological damage following iso-immunization with testis.


The effect of progestagens on amino sugar metabolism in endometrium.


Relationship between stored spermatozoa and the uterine epithelium in the pipistrelle bat (Pipistrellus pipistrellus).


Effects of a hyperthyroid compound on appetite, body weight change and oestrus inhibition in gilts fed a dithiocarbamoylhydrazine (ICI 33828).


A picture identification test for hearing-impaired children.


Hepatocellular changes associated with allylisopropylacetamide-induced hepatic porphyria in rats.


Antibiotics of limited usefulness.

Antibiotics of limited usefulness.


The effect of hypoxia on the renin-angiotensinogen system.


Type B particles in human milk.

Type B particles in human milk.


Fine structure of amyloid-containing livers from white Pekin ducks.


Dopamine sites in the basal ganglia.

Dopamine sites in the basal ganglia.


Identification of a naturally occurring goitrogen in water.


Fetal erythropoiesis: erythropoietin effects on cultured cells.


Acquired hemophilia.

Acquired hemophilia.


Studies on the possible presence of the urate-binding alpha-1-alpha-2 globulin in human erythrocytes.


Electron microscopic study of the tubules in human carious dentine.


Canine copro-immunoglobulins.

Canine copro-immunoglobulins.


Concluding remarks on the cholera workshop.


Comments on immunization.

Comments on immunization.


Reactions of staphylococcal antigens with normal sera, gamma G-globulins, and gamma G-globulin fragments of various species origin.


Orbital hemangiopericytoma or vascular meningioma?


Healing in rat lung after subacute exposure to nitrogen dioxide.


Papillary deposition of fibrin, a characteristic of initial lesions of dermatitis herpetiformis.


Papillary deposition of fibrin in iodide reactions in dermatitis herpetiformis.


SLE-like deposition of immunoglobulins in the skin in rosacea. A clinical and immunofluorescent study.


Auto-immune serum factors and IgA elevation in lymphogranuloma venereum.


An adaptation of the Feldman and MacCulloch approach to treatment of homosexuality by the application of anticipatory avoidance learning.


Immunological and morphological studies on human adenovirus type 31.


Notes on the effect of measles and measles vaccine in a virgin-soil population of South American Indians.


The role of core gender identity in the genesis of perversions.


Evidence against the presence of fibres or chemically distinct layers in the cell wall of Saccharomyces.


Thyroid function in male killifish, Fundulus heteroclitus, adapted to high and low temperatures and to fresh water and sea water.


Effects of lithium on thyroid function. (A review).


Effects of atropine and eserine on the electroencephalogram, on behaviour and on light-induced epilepsy in the adolescent baboon (Papio papio).


On automatic methods of sleep staging by EEG spectra.


Conditioned neuronal responses at various levels in conditioning paradigms.


A comparison of monocular visually evoked potentials in human neonates and adults.


Analysis of somato-sensory, auditory and visual averaged transcortical and scalp responses in the monkey.


Influence of increased local cholinergic activity on discharge patterns of hippocampal foci.


A case of reading epilepsy with observations on the effect of sleep deprivation and fasting on eeg correlates.


The technique and preliminary results of intraventricular EEG recording (brain-stem EEG).


Suppression of electrical activity. Pathophysiological implications.


Effects of haloperidol and trifluperidol on the sleep cycle of the cat.


Autonomic phenomena in the subcortical epilepsies.


Changes of the skin impedance in the spinal cord lesions.


Evoked resistance shifts: acute and chronic experiments at cortical and subcortical structures.


Induced neuron activity and principle of modulation and selectivity.


Epileptic seizures provoked by intermittent photic stimulation in non-epileptic patients.


Sleep disorders in brain lesions.

Sleep disorders in brain lesions.


Significance of the occipital and vertex response.


Effects of the enucleation of an eye upon the cortical visual evoked responses in the albino rat.


Evoked responses and perceptual changes.


Hippocampal theta rhythm in relation with unit discharges in septum and hippocampus.


The vertex non-specific evoked potential and latency of contingent ngative variation.


Somato-sensory evoked responses in patients with unilateral cerebral lesions.


Visual and somato-sensory evoked responses from mongoloid and normal children.


Effects of thalamic stimulation and thalamotomy on the H reflex.


Influence of cortical incisions on synchronization pattern and travelling waves.


Investigation of the amygdaloid and olfactory electrographic response in the cat after toxic dosage of lidocaine.


Volume-conducted potentials in response to auditory stimuli as detected by averaging in the cat.


Orbital cortex of the cat's brain and the orienting reflex to acoustic stimuli.


Simulation of electromyograms showing interference patterns.


Effect of local temperature on the resting membrane potential in rat muscle.


Constant intensity sound stimulation with a bone conductor in the freely moving cat.


A numerical approach to matching amplification for the spectral analysis of recorded EEG.


EEG, epilepsy and precocious puberty.

EEG, epilepsy and precocious puberty.


EEG findings in poisoning by endosulfan (C9H6O3Cl6S).


Benign focal epilepsy in children.

Benign focal epilepsy in children.


The EEG in "acute labyrinthitis".

The EEG in "acute labyrinthitis".


Some studies of rod monochromatism: a dominant pediree.


The influence of anti-psychotic drugs on the EEG of mental patients.


EMG in velo-pharyngeal incompetence.

EMG in velo-pharyngeal incompetence.


Relationships between nucleus lateralis posterior of the thalamus and the superior colliculus in the cat.


EEG evolution of two cases of late Jakob-Creutzfeldt syndrome.


EEG in cardiac surgery: survey of 80 cases.


Somaesthetic evoked potentials recorded on the scalp in six cases of hemispherectomy.


Some difficult problems of interpretation in carotid compression.


Neurological and electrographic high pressure syndrome.


Use of echography with EEG in the diagnosis of cerebral haematomas.


New electrode-carrying spectacles for the recording of ocular movements.


New electronic designs for quantitative EEG.


Quantitative electroencephalography: the limits of individual and collective variability of cerebral electrogenesis in normal man.


The functional epilepsy of maturation: the use of "vertical" montages in EEG in the diagnosis of the form of epilepsy.


Technique of activation of experimental epileptic foci by using local disturbances of the blood-brain barrier.


Formation in man of secondary epileptic foci.


Concerning epileptic attacks of occipital origin.


Study of tonic activity during slow sleep: role of the experimental situation of sensory deprivation.


Experimental deprivation of dreaming sleep in the normal subject.


One of the problems posed by the diagnosis of irreversible coma:the flat EEG and pupil diameter.


EEG study during vaccination against measles with the Schwarz vaccine.


The post-concussional syndrome and the EEG, correlations in 3,100 cases.


EEG investigation of vertebro-basilar circulatory insufficiency due to cervical spondylosis.


Hormonal influences on choline concentrations in rat tissues.


Vaccinia virus infection of synchronized pig kidney cells. Vaccinia virus replication was studied in pig kidney (PK-15) cells synchronized by excess thymidine treatment. It was found that virus replication with concomitant inhibition of mitosis can occur at any period in the life cycle of the cell except for the narrow span of time from late prophase through telophase. Cells infected at this time continue to divide, and vaccinia does not replicate until cell division is complete.


Immunofluorescence and cytochemical studies of visna virus in cell culture. Sequential morphological changes occurring in sheep choroid plexus cells infected with visna virus were studied by direct immunofluorescence, acridine orange, and hematoxylin and eosin staining methods. Specific immunofluorescence was first detected in the perinuclear cytoplasm of solitary cells 24 hr after infection. As the infection progressed, viral antigen appeared in an increasing number of cells, and rounded globular cells with long slender processes harboring intense fluorescence were seen. Nuclear fluorescence was not observed in infected monolayers. Polykaryocytes formed within 6 hr after inoculation due to the direct cell-fusing effect of the virus inoculum did not show specific fluorescence. Viral antigen was found, however, in the cytoplasm of multinucleated giant cells in cover slips harvested after new infective virus had been released, and later in the course of infection circular fluorescent inclusions were seen in the cytoplasm of polykaryocytes. Comparable eosinophilic inclusions were observed in hematoxylin and eosin preparations, and acridine orange staining of infected monolayers demonstrated similar inclusions which fluoresced with the color characteristic of single-stranded nucleic acid and were susceptible to digestion with ribonuclease. Visna virus appears to be a ribonucleic acid virus which replicates in the cytoplasm.


Histochemical investigation of epithelial mucosubstances in the uterine isthmus.


Dengue virus plaque development in simian cell systems. II. Agar variables and effect of chemical additives. Dengue type 2 virus, strain New Guinea B, plaqued with equal facility and titer under overlays containing six different grades of commercial agar in the LLC-MK(2) cell system. Doubling the agar volume on LLC-MK(2) cell monolayers increased the plaque development time of dengue type 1, strain Hawaii. Storage of agar at 56 C reduced or totally abolished dengue type 4, strain H-241, plaque titer in LLC-MK(2) cells. The influence of six known virus plaque-enhancing compounds on plaque development of all dengue virus serotypes was studied in two continuous simian kidney cell lines, LLC-MK(2) and Vero. In the absence of any chemical additive, plaque development of all dengue serotypes was more rapid (4 to 10 days) in the LLC-MK(2) line than in the Vero line (6 to 13 days). Increased plaque development time of type 1, strain Hawaii, by pancreatin and plaque-size doubling of dengue types 1 and 4 was the only advantage conferred by the addition of six chemical additives in the LLC-MK(2) cell system. Dengue types 1 and 6 failed to plaque in the Vero cell system unless aided by a plaque-enhancing compound; plaques of dengue types 2, 3, 4, and 5 appeared sooner (2 days) and were increased in plaque diameter. The optimal DEAE concentration for plaquing dengue type 1, strain Hawaii, was 100 mug/ml; plaque development either failed at lower concentrations or was inhibited at higher (200 mug/ml) concentrations.


Histopathology of Listeria monocytogenes after oral feeding to mice. Ingestion by mice of Listeria monocytogenes in drinking water induced micro-abscesses of the liver and ulcerative enteritis. In pregnant mice, these lesions were larger and more extensive than in nonpregnant female and male mice. Pregnancy is interrupted by a purulent panmetritis and necrotizing placentitis. The early microabscess is unique in that it consists of monocytic cells with bizarre-shaped nuclei. The experimentally induced pathological changes in livers and intestines of mice used in this study are similar to those observed in listeric neonatal septicemia of human infants.


Knops-Helgeson (Kna), a high-frequency erythrocyte antigen.


Accuracy of smallpox diagnosis by immunfluorescence with a purified conjugate. A direct fluorescent-antibody test for smallpox is described which utilizes a conjugated antivaccinia serum that was purified by diethylaminoethyl fractionation. The purity of the conjugate was analyzed by density gradient centrifugation, and specific staining of smallpox and nonsmallpox specimens was measured quantitatively by a photovoltmeter. Variola elementary bodies were identified in all of the specimens of vesicular and pustular fluid collected from 50 smallpox patients, and no false-positive diagnoses were made on specimens from 27 patients with varicella or other nonpox viral exanthems. However, 63.8% of the specimens of vesicular and pustular fluid smeared on slides in the field were unusable because of bright nonspecific fluorescence. For this reason, the fluorescent-antibody test does not compare favorably with other routine laboratory tests for smallpox.


Degradation of endrin, aldrin, and DDT by soil microorganisms. Twenty microbial cultures which had been shown to degrade dieldrin were tested to determine their ability to degrade endrin, aldrin, DDT, gamma isomers of benzenehexachloride (gamma-BHC), and Baygon. All isolates were able to degrade DDT and endrin, whereas 13 degraded aldrin. However, none of them was able to degrade Baygon or gamma-BHC.


Cerumen gland neoplasia.

Cerumen gland neoplasia.


Suppression of primary Rh-immunization by anti-Rh.


Ekbom's syndrome and burning paraesthesiae. A biopsy study by vital staining and electron microscopy of the intramuscular innervation with a note on age changes in motor nerve endings in distal muscles.


The Jackdaw series on the History of Medicine and Science.


Morphological abnormalities of the terminal neuromuscular apparatus in recent juvenile diabetes.


Pathological changes in the central and peripheral nervous system of young long-term diabetics. The terminal neuro-muscular apparatus.


Methodological approaches to studies on the pancreatic islets.


Prophylaxis and clinical evaluation concerning measles virus for distemper immunization.


The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes.


Isolated histone fractions and the alkaline fast green reaction.


Glucose 6-phosphatase and thiamine pyrophosphatase activities in the jejunal epithelium of the mouse.


Neurosecretion in the scorpion Heterometrus swammerdami.


Role of thymus-derived lymphocytes in the secondary humoral immune response in mice.


Structural heterogeneity of kidney basement membranes.


Prevention of pregnancy in the rabbit by subcutaneous implantation of silastic tube containing oestrogen.


Air pollution: CO not ok in Europe.

Air pollution: CO not ok in Europe.


Histochemistry of motor neurons and interneurons in the cat lumbar spinal cord.


Axoplasmic flow rates in the monkey optic system.


Alpha 1-antitrypsin deficiency.

Alpha 1-antitrypsin deficiency.


Antimycotics in hypertrophy of the prostate.


Serologic specificity of platelets.

Serologic specificity of platelets.


Comparative studies of anti-Lp sera.

Comparative studies of anti-Lp sera.


The sclerotia of Coprinus lagopus.

The sclerotia of Coprinus lagopus.


Practical nurse training for Chicago students--a multi-media approach.


The use of fluorescence microscopy in oral diagnosis.


Lupus erythematosis. A case report.

Lupus erythematosis. A case report.


Current trends in oral therapeutics.

Current trends in oral therapeutics.


Preventive aspects of endodontics.

Preventive aspects of endodontics.


"Two small pimples on my tongue".

"Two small pimples on my tongue".


Dental health education.

Dental health education.


Effect of thyroid activity on fatty acid composition of serum lipids.


Seven-year-old gets new dentures.

Seven-year-old gets new dentures.


Investigations on the effect of laser radiation on the dental pulp in rabbits.


Studies on the etiology and pathogenesis of epidermodysplasia verruciformis Lewandowski--Lutz.


Preliminary report on a new aversion therapy for male homosexuals.


Immunofluorescence of epithelial skin tumors. I. Patterns of intercellular substance.


Immunofluorescence of epithelial skin tumors. II. Basement membrane.


Malignant hepatoma in the Bantu.

Malignant hepatoma in the Bantu.


Determination of renin in the corpuscles of Stannius of the teleost.


Inhibition of metamorphosis in Ambystoma tigrinum by prolactin.


P.B.I. and R.A.I. studies in thyroid diseases.


Localization of lactate dehydrogenase activity in the cells of the fish (Xiphorphorus helleri) eye.


Morphological and biophysical identification of fibrous proteins in the amniote epidermis.


Oral dosage form design and its influence on dissolution rates for a series of drugs.


A study of immunoglobulin levels in Singapore infants and children.


Human cell cultures. Their use in the investigation and diagnosis of disease.


Histamine liberation and histamine formation in traumatic shock and in shock-resistance. I. Histamine release.


Alpha-fetoprotein: occurrence in certain malignant diseases and review of clinical applications. Several large studies have established the usefulness of alpha fetoprotein (AFP) detection as a diagnostic test in patients suspected of having primary hepatoma.  in the current study, 65% of patients from Hong Kong and 50% of eastern U.S. patients with hepatocellular carcinoma had AFP in their sera.  AFP was not found in normal adult sera in any of the reported series.  In this series, AFP was not detected in sera of patients with other hepatic diseases, often associated with AFP occurrence, or in sera of 6 patients with embryonal cell carcinoma of the testis though that disease has also been associated with AFP detection in sera.  However, the occurrence of AFP in various tissue extracts was detected in 1/2 extracts of primary hepatoma and in 2/6 extracts of embryonal cell carcinoma of the testis, but not in other tumors.  The hepatoma extract containing AFP was from a patient with AFP in serum;  the serum from the other patients with hepatoma was negative.  Sera from the patients with testicular cancer were not available for testing.  Theories on the function of AFP and its relationship to carcinogenesis are also discussed.


Histamine liberation and histamine formation in traumatic shock and in shock-resistance. II. Histamine formation.


Double contrast cystography in inverted position for radiographic demonstration of prostatic enlargement.


Factors influencing platelet function: adhesion, release, and aggregation.


Chemistry and drug allergy.

Chemistry and drug allergy.


Aetiology and pathogenesis of peptic ulcer.


Plasma histamine and coagulation time of the blood in dogs after administration of different histamine releasers.


Dogs refractory to compound 48/80 and sinomenine.


The present position of thyroidectomy.

The present position of thyroidectomy.


Structure and function of mucosal antibodies.


Chemical causes of pain and itch.

Chemical causes of pain and itch.


Treatment of ventricular extrasystoles and tachyarrhythmias in acute myocardial infarction.


Salient features of nonsaccharolytic and weakly saccharolytic nonfermentative rods.


Ultrastructure of Vi phages I to VII of Salmonella typhi.


Epizootic hemorrhagic disease virus of deer: an electron microscopic study.


Renal acidification and hypergammaglobulinemia. A study of rheumatoid arthritis.


Ankle jerk estimation and the thyroid function in a health survey.


Electron microscopy of adenosine triphosphatase in Escherichia coli cells.


Urinary excretion of serum proteins in renal disease.


Renal interstitial cells: prostaglandins and hypertension. A pathophysiological review of the renal medullary interstitial cells and their medullary interstitial cells and their relationship to hypertension.


Morphogenesis and ultrastructure in Dictyostelium.


Migraine as a cyclic disease with latent and overt components--effects with an antaminic drug.


BC-105--a new serotonin antagonist in the treatment of migraine.


Techniques for controlling the oxides of nitrogen.


Deactivation of automobile exhaust control catalyst.


Kinetics of initiation of germination of Bacillus pumilus spores by hydrostatic pressure. The kinetics of initiation of germination and inactivation by hydrostatic pressure of phosphate-buffered Bacillus pumilus spores is shown to be a consecutive first-order process at 25 C. The effect of increasing pressure at constant temperature was studied, and rate constants were derived by using the criteria of heat resistance, refractility, and stainability. The calculated volume change of activation (DeltaVdouble dagger) was -139 +/- 6 cm(3)/mole for loss of heat resistance, -158 +/- 8 cm(3)/mole for the loss of refractility, and -153 +/- 4 cm(3)/mole for the change in permeability to dilute stains for the pressure range 800 to 1,010 atm at 25 C. It is suggested that the spore exists as a Donnan phase and that pressure triggers germination by influencing the equilibrium.


Relation between deoxyribonucleic acid and intracytoplasmic membranes in Escherichia coli O111a. The possibility of a relationship between intracytoplasmic membranes and deoxyribonucleic acid (DNA) in Escherichia coli O111a(1) has been investigated. To facilitate this investigation, a simple enzymatic assay for the amount of internal membrane present in a culture was developed. This assay was then used to show that the appearance of intracytoplasmic membranes is accompanied by an increase in the DNA content of the cells. Electron micrographs have confirmed this observation and have shown DNA to be in contact with the intracytoplasmic membranes. Extensive membranes were observed at sites of apparently unsuccessful attempts at cell division. These observations led to the conclusion that the internal membrane formed by strain O111a(1) represents "extra" membrane, which is functional in that it contains sites for DNA replication, but is produced in excess because the organism is somehow defective in its regulation of membrane synthesis.


Comparative effects of four uncouplers on the enthalpy change for mitochondrial oxidation of succinate by ferricyanide.


Premature formation of glucokinase in developing rat liver.


Cystic prostatic hypertrophy in 2 inbred lines of Syrian hamsters.


Antimicrobial defense mechanisms in the Salmonella typhimurium associated ex-germfree rat.


Uveitis and intraocular treponemes.

Uveitis and intraocular treponemes.


Clinical test for evaluating donor corneas.


The vector potential of Demodex folliculorum.


On the spread of the blood-group-incompatible married couples in Bulgaria.


False blood group determination after massive incompatible blood transfusions.


Etiology and prophylaxis of immunological haemolytic transfusion reactions.


A new electrocardiographic evidence of pulmonary embolism.


Experience with large-dose intravenous antithymocyte globulin in primates and man.


Immunosuppressive assay of antilymphoblast globulin in man: effect of dose, histocompatibility, and serologic response to horse gamma globulin.


Glomerular events during the initial phase of rat Masugi nephritis.


Ultrastructure of cells stained with acridine orange.


Glycogen in normal human iris pigment epithelium.


Histopathology of melanotic sheep liver. 1. Histology and non-enzymic histochemistry.


Histopathology of melanotic sheep liver. 2. Enzymic histochemistry.


Appearance, characteristics and malignancy of somatic hybrid cells between L and Ehrlich ascites tumor cells formed by artificial fusion with UV-HVJ.


Japanese encephalitis purified vaccine. II. Purity of the mouse brain vaccine purified by ultracentrifugation.


Ruthenium red staining of rat glomerulus. Perfusion of ruthenium red into normal and nephrotic rat kidney.


Sodium rhodizonate staining of the keratogenous zone of the hair follicle and lingual papilla.


The staining of nerves in serial sections.


Innervation of pulmonary and bronchial blood vessels of the dog.


Immunoglobulins in Jamaicans and Nigerians with immunogenetic typing of myeloma and lymphoma in Jamaicans. Serum IgG concentration was lower in Jamaicans than in Nigerians. The maternalfoetal IgG ratio was also lower in Jamaican sera than in Nigerian sera. It is suggested that endemic malaria in Nigeria may be responsible for these differences. The higher IgM concentration in the Nigerian cord sera may be further evidence of this. Eighteen new cases of myeloma were detected in Jamaicans between August 1966 and May 1967. Based on Gm typing, only two of these showed evidence of mixed white ancestry. All the others had the typical Gm groups of Negroes. Similarly, only two patients out of a total of 17 with malignant lymphoma showed evidence of mixed white ancestry. Twelve of the patients with myeloma showed serum proteins of the IgG type, five were IgA, and one had only light chains in the serum. The majority of the patients had myeloma protein of the kappa type. The Gm typing suggested that six patients had myeloma protein of the gamma1 heavy chain subclass, and one patient had a gamma3 subclass heavy chain, the remainder belonging most likely to the gamma2 heavy chain subclass since gamma2 occurs about four times as frequently as gamma4.


Multispot immunofluorescence: a simple semi-automatic method of processing large numbers of tests.


Gram stain modified to improve colour contrast.


Atypical leukaemia of long duration with monoclonal hypergammaglobulinaemia. A patient with atypical acute leukaemia is described. This patient has, in addition, monoclonal IgG hyperglobulinaemia without myelomatous lesions and is living and well three years after diagnosis. The cell types found in the blood and in the bone marrow are atypical, and the histochemical findings are discussed. The relationship between monoclonal hypergammaglobulinaemia and malignant blood diseases is also discussed, and the literature on the subject reviewed.


Immunological and histological studies in primary biliary cirrhosis. Thirty-one patients with primary biliary cirrhosis in whom adequate histological liver material was available were studied by immunological and histological methods. There was no statistically significant correlation between individual histological features and the level of serum mitochondrial antibodies. A relationship between the duration of symptoms and histological stage of the disease supports the present concept of its evolution. However, several stages were often identified in the same specimen. Four cases with negative mitochondrial antibodies were similar to the other 27 clinically and histologically.


Anaesthetics for the student nurse.

Anaesthetics for the student nurse.


Hyalinosis cutis et mucosae: histochemical study of hyaline material.


Progressive multifocal leukoencephalopathy. A virus disease?


Rubella virus: direct fluorescence.

Rubella virus: direct fluorescence.


Malacoplakia of the testis.

Malacoplakia of the testis.


Luteoma of pregnancy. A pseudotumor.

Luteoma of pregnancy. A pseudotumor.


Crystalline inclusion pneumonia following the use of hytrast in bronchography.


Histiocytic medullary reticulosis.

Histiocytic medullary reticulosis.


Cytology of synovial fluid in rheumatoid arthritis.


The use of stereo reels as an aid in the teaching of pathology.


Microanalysis and characterization of acidic glycosaminoglycans in human tissues.


Preparation of immunoglobulin concentrates from human serum by chromatography on controlled pore glass.


Alterations in polyacrylamide gel disc electrophoretic patterns of hemoglobin after exposure to fluorescent light. Electrophoretic separation of some hemoglobin variants on polyacrylamide gels.


Micro gel electrophoresis modification for dilute (protein) solutions.


The significance of secretory immunoglobulins.


Changes in serum proteins due to lesion or resection of the olfactory bulbs of the rat.


Basic proteins of mouse ova and blastocysts.


The influence of iodine-labelling on the non-specific fixation of immunoglobulins to tissues.


Procedures for immunochemical study of histamine release from leukocytes with small volume of blood.


Morphological changes in diencephalic nuclear areas after administration of anterior pituitary hormones in the dog, guinea-pig and rabbit.


Plane xanthomatosis associated with myelomatosis.


Polymorphism of malate dehydrogenase in Ascaris suum.


Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci.


Starch gel electrophoresis of enzymes--a compilation of recipes.


Radiotherapeutic response of plasma cell tumors associated with monoclonal gammopathy.


Pleural pericardial window for palliation of cardiac tamponade due to cancer.


The determination of protein bound iodine by neutron activation analysis.


The royal road to the unconscious: changing conceptualizations of the dream.


The relation of daytime events to the dreams that follow.


Forensic odontology with care report.

Forensic odontology with care report.


Corneal staining prior to contact lens wearing.


A study of three and nine o'clock staining after unilateral lens removal.


Studies of an in vitro binding reaction between thyroid microsomes and long acting thyroid stimulator globulin (LATS). I. Development of solid-state competitive binding radioassay methods for measurement of antimicrosomal and antithyroglobuin antibodies.


Re-evaluation of thyroxine binding and free thyroxine in human serum by paper electrophoresis and equilibrium dialysis, and a new free thyroxine index.


Plasma TSH levels in endemic goiter subjects.


The nature of the reaction of antigen with lymphocytes from rabbits infected with Schistosoma mansoni on the release of histamine from rabbit platelets.


Application of the paired radioiodine-labeled antibody technique (PRILAT) to the detection of adenovirus 12 tumor (T) antigen.


Immunoglobulins of the hamster. II. Characterization of the gamma A and other immunoglobulins in serum and secretions.


Different inherited levels of DNA repair replication in xeroderma pigmentosum cell strains after exposure to ultraviolet irradiation.


A time-specific effect of UV-irradiation on cells progressing from G2 into metaphase.


Staining of mast cells and eosinophiles in the sheep skin.


Antigen receptor molecules: inhibition by antiserum against kappa light chains. Rabbit antiserum against mouse kappa chains, the predominant class of light chains found in mouse immunoglobulins, inhibits the immune response in vitro of mouse spleen cells to erythrocyte antigens. The inhibition becomes irreversible if the mouse spleen cells are treated briefly with both antiserum to kappa chains and complement.


Immunoglobulins: structure, function and relation to the eye.


Isolation of an arginine-rich protein from particles of adenovirus type 2.


Some properties of hybrid viruses reassembled in vitro.


Biophysical studies of the normal nail.

Biophysical studies of the normal nail.


Studies of common baldness in the stumptailed macaque. 3. DNA synthesis in regrowing hair.


The relationship of esters and free fatty acids in the skin surface lipids in persons with some dermatoses. An infra red spectroscopic study.


Acid protease activity in human fetal skin.


Aryl sulfatase activity in human fetal skin.


Contact dermatitis in the atopic.

Contact dermatitis in the atopic.


Passive transfer of chromium allergy in guinea-pigs.


Eosinophilic pustular folliculitis.

Eosinophilic pustular folliculitis.


Further histological investigations on malignant degeneration of cutaneous lesions in epidermodysplasia verruciformis.


Coagulation and fibrinolysis in chronic panniculitis.


Basal cell carcinoma in association with acrodermatitis chronica atrophicans herxheimer.


Angiokeratoma of the scrotum (Fordyce). A case report on response to surgical treatment of varicocele.


Antipruritic effect of urea solutions. An experimental and clinical study.


A double-blind controlled trial of Whitfield's ointment and Variotin in ringworm infections with a two year "follow-up".


Plastic film as protection against primary irritants.


Coverage of cutaneous ulcers in Werner's syndrome.


Dendritis (herpetic) keratitis. 3. Follow-up examination of the percorneal film. Fischer-Schweitzer's fluorescein pattern, and vital staining.


Audio-visual speech perception. A preliminary report.


Electrical activity from single neurons in Auerbach's plexus.


Cytoplasmic synthesis of RNA in the sea urchin embryo.


Radioimmunological studies on the long-acting thyroid stimulator.


Effect of prolactin, growth hormone and ACTH on the urea excretion of bullfrog tadpoles during normal and induced metamorphosis.


Separation of malignant cells from transplantable rodent tumors.


The turtle bladder. I. Morphological studies under varying conditions of fixation.


The turtle bladder. II. Observations on the epithelial cytotoxic effect of amphotericin B.


Histochemical demonstration and localization of sialoproteins in the glomerulus.


Staining of tissue polycations by anionic dyes in salt solutions with special reference to gingiva.


Secretion of iodoalbumin and iodoprealbumin by a congenital goiter containing thyroglobulin and the iodoalbumins.


A comparison of Alcian Blue-aldehyde fuchsin and peroxidase-labeled antibody staining techniques in the rat adenohypophysis.


Phosphotungstic acid not a stain for polysaccharide.


Phosphotungstic acid as a specific electron stain for complex carbohydrates.


Salivary glands of heteromyid rodents, with a summary of the literature on rodent submandibular gland morphology.


Diagnosis of Graves' ophthalmopathy without hyperthyroidism: long-acting thyroid stimulator (LATS) determination as laboratory adjunct.


Jejunal biopsy.

Jejunal biopsy.


Good signs can help control visitor and staff traffic.


Penicillin skin tests as predictive and diagnostic aids in penicillin allergy.


Kidney tissue activator of fibrinolysis in relation to pregnancy.


Cast-off endometrial cilia in vaginal smears.


Schiller negative or Schiller positive?

Schiller negative or Schiller positive?


Fibrinolytic activity of the pregnant uterus, decidua, and placenta in rat.


Endometrial morphology and polyethylene intrauterine devices. A study of 200 endometrial biopsies.


Antibodies of Rh isoimmunization.

Antibodies of Rh isoimmunization.


Binding of AET by serum proteins.

Binding of AET by serum proteins.


The isolation of picornaviruses from cats with respiratory disease.


Virus diseases of the respiratory tract of cats. 1. Isolation of feline rhinotracheitis virus.


Abnormal extracellular components in Wilms' tumor.


Evidence for the presence of anti-Burkitt tumor globulins in pooled human immune globulins.


Malignant mixed tumor of the lung.

Malignant mixed tumor of the lung.


Effect of oncolytic anaerobic spores on animal cell cultures.


Studies on IgA. II. Isolation of IgA from small volumes of human serum by immunoabsorption.


The distribution and renewal of RNA in retinal rods.


The relationship between antibody affinity and the efficiency of complement fixation.


Early mast cell responses in mouse popliteal lymph nodes to localized primary antigenic stimuli.


The assessment by immunofluorescence methods of humoral anti-myelin antibodies in man.


Cells involved in the immune response. XVII. The elution of antigen by antigen-reactive cells from antigen-sensitized glass bead columns. The high affinity of these cells for the glass bead-adsorbed antigen.


Some characteristics of anti-dinitrophenyl antibody of the gray snapper.


Physicochemical and antigenic studies on human gamma E in respiratory fluid.


An immunogenic polysaccharide-protein conju- gate.


Further electron microscopic observations of bacteriochlorophyll protein crystals.


Suppression of IgM and IgG synthesis in young rabbits by 6-methyl mercaptopurine treatment.


The role of histamine and catecholamines in anaphylatoxin shock as compared to the anaphylactic shock.


Coincidence of pernicious anaemia and IgA-K myeloma. A clinical model of the relation between autoimmune disease and tumour from immunocompetent tissue.


Histophysiological examination of the optic tentacle of pulmonates. II. Cytochemistry of the special and secretory cells.


Renal transplantation in the inbred rat. XVI. Effects of salicylates and anticoagulant drugs on rejection.


The morphology of the pineal organ in the teleost, Clarias lazera, C.V.


Morphological and histochemical studies on the secretion of the vitelline gland of trematodes.


Cytochemical studies of acute leukemias.


Daily and intermittent regimens: third IUAT chemotherapy investigation. A controlled trial of three regimens of self-administered and supervised chemotherapy for pulmonary tuberculosis. Clinical aspects.


Pathogenesis of anemia in Costa Rica. Epidemiologic study of hemoglobin and serum protein levels and hookworm infection in children.


Three initial streptomycin supplements to standard isoniazid-thiacetazone chemotherapy. East African-British Medical Research Council investigation.


A further contribution on the incidence of ring shaped nucleoli and micronucleoli in mature human lymphocytes.


Analysis of the role of the professional staff nurse in the operating room.


Average variation of the blood components of four fish.


A concept of allergy with reference to oral disease.


Erythrocyte membrane proteins.

Erythrocyte membrane proteins.


Effects of immune reactions on the red cell membrane.


Experimental model of massive pulmonary embolism in the rat.


Experiments upon the reflex mechanism of massive pulmonary embolism.


Precipitating antibody in the sera of patients treated cryosurgically for carcinoma of the prostate.


Haemodynamic effects of the auxiliary ventricle and left heart bypass with subsequent metabolic and morphological changes in the myocardium.


Conformational changes in chymotrypsin detected with antibodies. 3. On the antigenic determinant groups of chymotrypsins.


Detection of fibrinogen degradation products by use of antibody coated latex particles. The possibilities and limits of the method.


Production site of bleeding factor. (Acquired morbus von Willebrand).


Ultrastructure of Debaryomyces hansenii.


Streptococcal A-carbohydrate antigen in granulomata of mouse liver after intravenous injection of heat-killed group A streptococci.


The histopathology of caviar tongue. Ageing changes of the undersurface of the tongue.


Isolation and chemical characterization of gas-vacuole membranes from Microcystis aeruginosa Kuetz. emend. Elenkin.


Virus hepatitis.

Virus hepatitis.


Hepatitis-associated antigen in chronic liver disease.


Children of mothers who took L.S.D. in pregnancy.


Rosette tests in autoimmune haemolytic anaemias.


Unimpaired mucociliary clearance in the lung of a centenarian smoker.


Routine operative cholangiography.

Routine operative cholangiography.


An edge on the Lancet.

An edge on the Lancet.


Diagnosis of respiratory infections by an immunofluorescent technique.


Flocculation tests, oral contraceptives, and malaria.


Lymphocyte abnormality in chronic mucocutaneous candidiasis.


Plasma-calcitonin in man.

Plasma-calcitonin in man.


Detection of bacteriuria.

Detection of bacteriuria.


Work of the anaesthetist.

Work of the anaesthetist.


Ketamine.

Ketamine.


Gastrointestinal bleeding.

Gastrointestinal bleeding.


Fibreoptic colonoscopy.

Fibreoptic colonoscopy.


Training in gastroenterology.

Training in gastroenterology.


Cyclic A.M.P. in depression and mania.

Cyclic A.M.P. in depression and mania.


Oral contraceptives and vascular anomalies.


Chest pain in the carcinoid syndrome.

Chest pain in the carcinoid syndrome.


Metachromasia in fibroblasts from a patient with Lafora's disease.


Leucocyte G.-6-P.D. deficiency.

Leucocyte G.-6-P.D. deficiency.


Pustular psoriasis.

Pustular psoriasis.


Old age at 86.

Old age at 86.


Australia antigen serology in the Holy Cross football team hepatitis outbreak.


Au-SH antigen in viral hepatitis in West of Scotland.


Validity of plasma-catecholamine estimations.


Influence of beta-blockade on myocardial threshold in patients with pacemakers.


In-vitro screening test for human malignant tumours before chemotherapy.


Two cases of transfusion malaria.

Two cases of transfusion malaria.


Sea-blue histiocyte disease in siblings.


Lymphocyte cytotoxicity: a possible in-vitro test for contact dermatitis.


Histocompatibility testing for leucocyte transfusion.


Different types of alpha-thalassaemia and significance of haemoglobin Bart's in neonates.


The respiratory jacket. A new method for measuring respiration.


Training of chemical pathologists.

Training of chemical pathologists.


Surgical treatment of bullous emphysema.


A new approach to the treatment of hypertension.


Paratyphoid.

Paratyphoid.


Hospital building maintenance: a priority.


The longshoreman's life.

The longshoreman's life.


A promising centenarian.

A promising centenarian.


The state of the union.

The state of the union.


Post-vagotomy dysphagia.

Post-vagotomy dysphagia.


Sex ratio in phenylketonuria.

Sex ratio in phenylketonuria.


Diagnosis of pneumocystis carinii infection.


Mnemonic for reporting bacteriocin and bacteriophage types.


Myalgia and bird-keeping.

Myalgia and bird-keeping.


Extra chromosome in "cat eye" syndrome.

Extra chromosome in "cat eye" syndrome.


"Cat eye" syndrome with normal chromosomes.


Rapid and sensitive assay for D.N.A. synthesis in leucocyte cultures.


Contamination of antiseptic solutions.

Contamination of antiseptic solutions.


Lithium depletion and atherosclerotic heart-disease.


Multiple frequency diagrams as table entries.


Spurious resistance to ethambutol.

Spurious resistance to ethambutol.


Attempts to augment thyrotropin secretion. Effects of methimazole, methimazole-iodide, vasopressin, and glucagon.


Attachment of carbohydrate to the variable region of myeloma immunoglobulin light chains. Approximately 15 per cent of the light chains from homogeneous immunoglobulins in patients with multiple myeloma contain an oligosaccharide group. Five human myeloma light chains that contained carbohydrate were studied. The sequence Asn-[unk]-Ser/Thr was at the site of carbohydrate attachment in all light chains. The carbohydrate group was attached to the asparagine residue of this triplet sequence which in all five light chains was located in the variable region. The occasional occurrence of carbohydrate in myeloma light chains is seen as the consequence of a variable region mutation creating an Asn-[unk]-Ser/Thr sequence to which carbohydrate is attached by an enzyme capable of recognizing the characteristic triplet sequence.


Atrial myxoma. An evaluation of clinical and laboratory manifestations.


Actinomycin-D and chiasma frequency in Schistocerca gregaria (Forskål).


On the function of the germ line chromosomes in the oogenesis of Wachtliella persicariae (Cecidomyiidae).


Developmental changes in the major inclusion bodies of polytene nuclei from larval tissues of the blowfly, Calliphora stygia.


Identification of human chromosomes by DNA-binding fluorescent agents.


The influence of DNA content and nuclear volume on the frequency of radiation-induced chromosome aberrations in Bufo species.


The localisation of radiation induced chromosome aberrations in relation to the distribution of heterochromatin in Secale cereale.


Quantitative histochemistry of acetylcholinesterase in rat hippocampal region correlated to histochemical staining.


The incidence and probable origin of melanin in the prostate.


Urinary tract infections following transurethral prostatectomy: with special reference to the use of antimicrobials.


Alteration of skin reactivity to local anesthetic drugs in guinea pigs.


[Indirect hemagglutination reaction in Northern Asiatic tick-borne rickettsiosis with antigen obtained from tissue culture].


A modified pyridine-silver stain for teased preparations of motor and sensory nerve endings in skeletal muscle.


Comparative spectroscopy of basic fuchsin, Schiff reagent, and a formalin-Schiff derivative in relation to dye structure and staining.


The host-parasite interface of strigeoid trematodes. VII. Ultrastructural observations on the adhesive organ of Diplostomum phoxini Faust, 1918.


The optic tracts of Rana pipiens.

The optic tracts of Rana pipiens.


Cerebroside and other polar lipids of the cerebrospinal fluid in neurological diseases.


Lactate dehydrogenase isoenzymes in muscular development of man and in nerve degeneration.


The effect of staphylococcal enterotoxin on the epithelial mucosubstances of the small intestine of rhesus monkeys.