Two distinct groups of immunoglobulin A(IgA) revealed by peptic digestion. Serum IgA M-components, secretory IgA separated from colostrum, and IgA from serum of patients with cirrhosis of the liver were digested with pepsin at pH 4.1. The IgA M-components segregated into two groups on the basis of their relative rates of peptic digestion. Serum and colostral IgA were digested at a total rate intermediate to that of the two groups of IgA myeloma proteins. It appeared, however, that colostral IgA may have been initially more resistant to peptic digestion than serum IgA. The variability in the rate of peptic digestion was not related to electrophoretic mobility, light-chain type, or IgA subclass. Experimental conditions related to enzyme to substrate ratio or to the pH of the reaction mixture did not appear to explain the differences found.These findings indicate that (a) two groups of IgA proteins can be distinguished on the basis of susceptibility to proteolysis with pepsin, and (b) secretory piece confers, at most, only a minor increase in stability to the IgA molecule against the digestive action of pepsin.


Alkali blue 5B--a rapid stain for elastin.


Kiton rhodamine B staining of fungi and bacteria in tissues for examination in visible and ultraviolet light.


Influences of an anti-ovulatory compound on the expression of vitamin D deficiency signs in laying hens.


Attempted experimental induction of amyloidosis in chickens.


Differentiation of live from dead spermatozoa in cock semen.


Effect of (-)-5-vinyl-2-oxazolidinethione on the radioiodine metabolism in growing chicks.


The influence of environmental temperature on the plasma proteins of domestic fowl.


Evidence for multiple gene control of a single polypeptide chain: the heavy chain of rabbit immunoglobulin. To determine the chemical basis for rabbit heavy chain allotypes, amino acid analyses were carried out on IgG and IgM antibodies isolated from rabbits which were homozygous a1 or a3 for the gamma chain locus and homozygous b4 for the light chain locus. The compositional differences between a1 and a3 IgM antibodies were found to be identical to those between their IgG counterparts. The identity of the allotypic amino acid replacements showed that the same genetic markers were present in the variable sequences of IgG and IgM heavy chains. Since the constant sequences of these heavy chains are controlled by different loci, these data demonstrated that rabbit heavy chains are coded by two separate germ-line genes, one producing the variable region and a second one of various genes producing the constant regions. The use of two antibodies, antiazophenylarsonate and antiazophenyl-beta-lactoside, permitted the compositions to be compared also on the basic of immunological specificity. The specificity amino acid replacements were found to be identical in the IgM and IgG heavy chains whether the two antibodies were isolated from and individual animal of a1 or a3 allotype. These results further support the conclusions of the allotype measurements that at least two genes code for the rabbit heavy chain.


Osmium tetroxide-zinc iodide reactive sites in the photoreceptor cells of the retina of the rat.


On the composition of the nucleolus with special reference to its filamentous structure.


Localization of carboxyl groups in gastric mucosa as possible sites of gastrin.


Degeneration and regeneration in the insect central nervous system. II.


The sensory papilla X-organ in Boreomysis arctica (Kroyer) (Crustacea Malacostraca Mysidacea).


Formation of alpha- and beta-type keratin in lizard epidermis during the molting cycle.


Degeneration and regeneration in the insect central nervous system. I.


Improvement of detection limits of flame-spectrophotometric determination of chlorinated organic pesticide residues.


Myocardial necrosis and mineralization in normal and Aleutian disease mink fed dexamethasone. Focal myocardial necrosis with mineralization occurred in mink fed the synthetic corticosteroid, dexamethasone, as a treatment for aleutian disease. Cardiac lesions occurred with equal frequency in steroid-fed controls and appeared to be related only to feeding of dexamethasone. Possible pathogenetic mechanisms are considered.


Liver biopsy in mink with Aleutian disease.


Giant neutrophil granules in the Chediak-Higashi syndrome of man, mink, cattle and mice. The percent of conventionally stained circulating neutrophils containing abnormal giant granules in Chediak-Higashi mink, cattle and mice is highly variable and strikingly less than the 100% found in neutrophils from similarly affected humans. In contrast, using either peroxidase or Sudan Black, it can be demonstrated that 100% of circulating neutrophils in all affected individuals of the four species studied contain the abnormal granules. Minor species differences in the shape of the granules were noted. The significance of these findings as well as the variations in granular staining by the several techniques employed are discussed.


An azure and eosin rapid staining technique.


The antibody molecule: structure and function.


Interaction of water-soluble amyloid fibrils with Congo Red and thioflavine T.


Studies on the phenotyping of hyperlipoproteinemias. Evaluation of cellulose acetate technique and comparison with paper electrophoresis.


Antigenic composition of hen's (Gallus domesticus) egg white.


A clinical trial with gamma benzene hexachloride in scabies.


Hematology, blood chemistry and protein polymorphisms in the white-tailed deer (Odocoileus virginianus).


Growth and reproductive performance of bulls and heifers fed purified and natural diets. 3. Blood proteins, glucose, amino acids and hair amino acid analysis (42-210 days of age).


Thin-layer chromatography of some acetylated adrenaline derivatives.


Stilphostrol therapy in 100 cases of prostatic carcinoma.


Screening for homozygous and heterozygous alpha 1-antitrypsin deficiency. Protein electrophoresis on cellulose acetate membranes.


Ultrastructure of human renal obsolescent glomeruli.


Increased plasma-free-fatty-acid concentrations and their significance in patients with acute myocardial infarction.


Sterilisation by ovariotexy. A reversible technique.


Creatinine clearance in patients with proteinuria.


The measurement of glomerular filtration-rate in renal disease.


Kidney preservation for transportation. Initial perfusion and 30 hours' ice storage.


Dietary fibre and serum-lipids.

Dietary fibre and serum-lipids.


Spontaneous evolution of ventribular septal defect into isolated pulmonary stenosis.


Smoking habits of oral contraceptive users.


Cardiac arrhythmias due to hypersensitivity. A report of ten ces.


Related disease--related cause?

Related disease--related cause?


Variable-height examination couch.

Variable-height examination couch.


Analgesic abuse and tumours of the renal pelvis.


A pure gene.

A pure gene.


Ectopic alkaline-phosphatase production by tumours.


The eosinophilic pneumonias.

The eosinophilic pneumonias.


Symptoms v. signs.

Symptoms v. signs.


Pharmacokinetic drug interactions.

Pharmacokinetic drug interactions.


Atheroma in a transplanted heart.

Atheroma in a transplanted heart.


Dental anaesthesia.

Dental anaesthesia.


Thrombocytopenic purpura as the only manifestation of rubella.


Polymyalgia rheumatica, temporal arteritis, and contact with birds.


Presymptomatic diagnosis of hepatitis.

Presymptomatic diagnosis of hepatitis.


A.L.S. and reticuloendothelial blockade.


Screening for neonatal hypoglycaemia.

Screening for neonatal hypoglycaemia.


Relapses during lithium therapy.

Relapses during lithium therapy.


Fluorouracil and radiotherapy in gastrointesinal cancer.


Should haemophilic haemarthroses by aspirated?


Rhesus-antibody development after abortion.


Creatinine excretion.

Creatinine excretion.


Hazard of vacu-drain system.

Hazard of vacu-drain system.


Control of anticoagulant treatment.

Control of anticoagulant treatment.


Immunosuppression and fatal measles.

Immunosuppression and fatal measles.


Abnormal forms of factor X.

Abnormal forms of factor X.


Intrathecal methotrexate.

Intrathecal methotrexate.


Treatment of early cancer of the breast.


Thrombocytosis induced by citrovorum factor.


Alexander Louis Wingfield, M.D. Lond., F.R.C.P.


John Stanley Arkle, O.B.E., M.B. Durh., F.R.C.S., F.R.C.S.E.


University freedom.

University freedom.


A simple extrasystole counter.

A simple extrasystole counter.


The immunology of Rh-haemolytic disease: a review.


Titres, activity or survival? The quantitation of anti-Rh (D) gamma globulin.


Alterations of and tissue reaction to polyvinyl alcohol sponge implants.


Periodontal disease in hypothyroid adult rats.


The isolation of nuclei from the yeast Schizosaccharomyces pombe.


A critical review of current clean air legislation.


Changes in electrical activity of the cockroach Blatta orientalis L. brain induced by anti-lobster brain antibody.


Cyanocobalamine as a support of the in vitro cell growth-promoting activity of serum proteins.


Demonstration of post-hypophysectomy changes in the neurosecretory system of a fish with in situ staining technique.


Localization of rhodopsin antibody in the retina of the frog.


The break-down of 131-I-gamma-globulin in the digestive tract of the new-born pig. 1. The intestinal absorption of [(131)I]porcine and bovine serum gamma-globulin after oral administration has been investigated in conscious pigs less than 20 hr old. Absorption was measured by the concentration of (131)I in venous blood during the 6 hr after feeding and also by the distribution of (131)I between homogenates of the alimentary tract and the rest of the animal at the end of the experiment.2. The concentration of (131)I in the blood was always low after feeding [(131)I]gamma-globulin, although a large proportion of the isotope fed was found to have left the alimentary tract. This indicated that much of the [(131)I]-gamma-globulin had been hydrolysed into fragments of low mol.wt. which were not retained in the plasma. There were no significant differences between results obtained with homologous and heterologous gamma-globulin.3. Examination by gel-filtration confirmed that, after feeding [(131)I]-serum gamma-globulin, much of the (131)I in the plasma was associated with material of mol.wt. less than 12,400 and demonstrated that the break-down of bovine gamma-globulin was comparable with that of homologous gamma-globulin.4. Comparison of the absorption of [(131)I]serum gamma-globulin from colostrum with that from a chloride solution with a similar Na(+) and K(+) concentration showed that, although the blood concentration remained low, colostrum reduced the hydrolysis of the labelled protein.5. This effect of colostrum could be simulated by the addition to the chloride solution of either the synthetic trypsin inhibitor Trasylol or a higher concentration of unlabelled protein.6. Gel-filtration of samples of the contents of the stomach, duodenum and terminal ileum after feeding [(131)I]serum gamma-globulin showed that proteolysis occurred at all these sites.


Proteolytic activity during the absorption of 131-I-gamma-globulin in the new-born calf. 1. Proteolytic activity within the small intestine of unsuckled calves less than 20 hr of age, anaesthetized with sodium pentobarbitone, has been assessed from the break-down of [(131)I]bovine serum gamma-globulin infused into the duodenum.2. Absorption of [(131)I]gamma-globulin was measured by analysis of venous blood, the levels of radioactivity attained in which were comparable with those when [(131)I]PVP K.60 (mean mol.wt. 160,000) was administered. When lymph collected from the thoracic duct during the absorption of [(131)I]gamma-globulin was injected into the femoral vein, the levels of radioactivity in the blood were close to those expected if the labelled material in the lymph had been retained within the plasma. These observations suggested that [(131)I]gamma-globulin was absorbed into the circulation of the anaesthetized young calf without significant break-down.3. Gel-filtration of lymph and plasma from calves fed [(131)I]gamma-globulin has confirmed that proteolysis before and during absorption was slight, since little (131)I labelled material of low mol.wt. was found.4. Gel-filtration of the contents of the alimentary tract from calves fed [(131)I]gamma-globulin showed that some hydrolysis occurred in the abomasum and duodenum and that this was reduced by barbiturate anaesthesia. Protein break-down in the terminal ileum was slight both in the conscious animal and in animals anaesthetized with sodium pentobarbitone.


Metachromasia elaborated.

Metachromasia elaborated.


Argyrophile and argentaffin reactions in individual granules of enterochromaffin cells of the Rhesus monkey, with a discussion on the identity of the "active" cells of the 5-hydroxytryptamine producing cell system of the gastrointestinal tract.


Alanine and alanine dehydrogenase in Streptomyces erythreus.


Lead-haematoxylin as a stain for endocrine cells. Significance of staining and comparison with other selective methods.


Thyroid function and blood thyroxine.

Thyroid function and blood thyroxine.


The role of thyroxine binding in the establishment of thyroid status.


Tinea granulomatosa cruris.

Tinea granulomatosa cruris.


Schiff and hematoxylin reactions of mammalian arterial elastica.


Indian childhood cirrhosis. The nature and significance of cytoplasmic hyaline of hepatocytes.


Chronic hepatitis. A clinicopathologic study of 75 cases.


Alpha cell granules in a pancreatic neoplasm. Association with peptic ulcers.


Release reactions of human platelets induced by thrombin and other agents.


Regulation of glycogen metabolism in liver by the autonomic nervous system. II. Neural control of glycogenolytic enzymes.


The incidence and structure of bronchopulmonary arteries in infancy and early childhood.


The development of thyroid function in the rat.


Morphological-biochemical correlations in rabbit red cell precursors synchronized by actinomycin administration.


The application of microbial enzymes which inactivate antibiotics: a review.


Implantation of sterile electrodes in chronic animals.


First clinical result with Depakine. Study of 30 cases.


A neurite-receptor complex in the avian lung: electron microscopical observations.


Demonstration of molecular size differences between closely related antigens by a simple gel diffusion tes.


Periodic acid-Schiff reaction combined with quantitative autoradiography of 3H-thymidine- or 35S-sulfate-labelled epithelial cells of colon.


Periodate oxidation of acid polysaccharides. 3. A PAS method for chondroitin sulphates and other glycosamino-glycuronans.


Kinetics of glucose 6-phosphatase in pancreatic islets as revealed by staining histochemistry.


Air quality criteria--toxicological appraisal for oxidants, nitrogen oxides, and hydrocarbons.


Epidemiological bases for possible air quality criteria for lead.


Application of eosin for differential staining of buffalo spermatozoa. IV. Use of opal blue-eosin.


Some effects of a single injection of chlormadinone acetate or methallibure on sexual function in the pubescent male animal. II. The rabbit.


Identification of the midpiece and tail of the spermatozoon during fertilization of human eggs in vitro.


Some effects of a single injection of chlormadinone acetate or methallibure on sexual function in the pubescent male animal. I. The ram.


A study on the permeability barriers between Disse's space and the bile canaliculus.


An electron microscopic study of single-cycle infection of chick embryo fibroblasts by influenza virus.


Electron microscopic study on the structure of septate and comb desmosomes.


Anaphylactic shock elicited by topical administration of bacitracin.


Isozyme genotype-environment relationships in natural populations of the harvester ant, Pogonomyrmex barbatus, from Texas.


Electrophoretic heterogeneity of mouse erythrocyte peptidases.


Immunodiffusion studies on the myxoviruses. II. Identification of influenza A-PR8 precipitins in the serum of normal rabbits.


Aflatoxin B1 carcinogenesis in lipotrope-deficient rats.


Formation of a sigma complex as a hypothetical rate-determining step in the carcinogenic action of unsubstituted polycyclic aromatic hydrocarbons.


Use of phenazine methosulphate (PMS) in the histochemical localization of lactic acid dehydrogenase (LDH) in the retina.


Differentiation of a cell line of myeloid leukemia.


The effect of thyroxine on peripheral thyroid hormone metabolism.


Studies on the local immunity of intestinal tract of chickens after oral administration of Newcastle disease virus.


The sites of antigen formation in different developmental stages of Clonorchis sinensis.


On some morphologic changes in the reticulo-endothelial system under the influence of Vitestrol, a synthetic estrogen.


Nasal polyposis.

Nasal polyposis.


Immunoelectrophoretic analysis of sheep serum using guinea-pig antisera to particulate antigens treated with sheep antiserum.


Dithizone and sulphide silver staining of the amygdala in the cat.


On the PAS reaction in acute paraerythroblastic hemoblastoses.


Chronology of the mitotic cycle of acute leukemia cells.


Lanthanum staining of the epidermal intercellular spaces. An electron microscopic study.


Further microscopic observation of molluscum contagiosum virus.


Ethanol in prevention of hyperbilirubinaemia in the newborn. A controlled trial.


Cell-mediated (delayed) hypersensitivity in patients with summer hay-fever.


Massive proteinuria associated with vesico-ureteral reflux.


Photosensitive dermatitis and renal tubular acidosis after ingestion of calcium cyclamate.


Mental-hospital admissions and aircraft noise.


In-utero detection of type-II glycogenosis (pompe's disease).


Effect of corticotrophin on plasma levels of human growth hormone.


Role of kidney in regulation of plasma-calcium.


Improved liver-biopsy needle.

Improved liver-biopsy needle.


More should mean different.

More should mean different.


Management of the abdominal surgical wound.


In prison.

In prison.


Biliary oesophagitis.

Biliary oesophagitis.


Supply of L-dopa for treatment of parkinsonism.


London noises.

London noises.


Familial cancer.

Familial cancer.


Fenfluramine overdosage.

Fenfluramine overdosage.


The art of setting multiple-choice questions.


Recruiting to general practice in England and Wales, 1961-69.


Atheroma in a transplanted heart.

Atheroma in a transplanted heart.


The course.

The course.


Growth hormone responses to saline and L-arginine.


The omohyoid syndrome.

The omohyoid syndrome.


Cyclamates.

Cyclamates.


Virus from baboons.

Virus from baboons.


Acute phenothiazine dystonia.

Acute phenothiazine dystonia.


Receptivity and the pill.

Receptivity and the pill.


Hypertension and the pill.

Hypertension and the pill.


Mydriatic responses to sympathomimetic amines in patients treated with L-dopa.


Dental anaesthesia.

Dental anaesthesia.


Iron-binding capacity of gastric juice.

Iron-binding capacity of gastric juice.


Oral lignocaine.

Oral lignocaine.


The changing British drug scene.

The changing British drug scene.


Models for histocompatibility in man.

Models for histocompatibility in man.


P.A.S. in the pan.

P.A.S. in the pan.


Care of the mentally subnormal.

Care of the mentally subnormal.


Fenfluramine overdosage.

Fenfluramine overdosage.


Depression of interferon production after A.L.S. treatment.


Induction of in-vivo resistance of trichomonas vaginalis to metronidazole.


Platelet-function tests.

Platelet-function tests.


Skin-grafting leg ulcers.

Skin-grafting leg ulcers.


B.C.G. vaccination and asparaginase.

B.C.G. vaccination and asparaginase.


Studies on the fine structure of the rat liver inner mitochondrial membranes negatively stained.


A cyclic variation in the exfoliation of cells from the urethra of the male mouse.


Psychiatric consultations for psychiatrists.


Carcinoma of the breast in women under thirty years of age.


Current concepts of tetanus prophylaxis.


Staging of surgical treatment of tetralogy of Fallot.


Serum antibody response in experimental human gonorrhoea. Immunoglobulins G, A, and M.


Detection of T. vaginalis in women. Comparison of "wet smear" results with those of two cervical cytological methods.


Nose-drop intoxication in an infant.

Nose-drop intoxication in an infant.


Talking books for the blind.

Talking books for the blind.


Antihistamine activity of the eosinophil.


Hexagonal lattice of subunits in the thick luminal membrane of the rat  urinary bladder.


Radioisotopes in clinical practice.

Radioisotopes in clinical practice.


Hypothyroidism.

Hypothyroidism.


Hyperfibrinogenaemia after ECIB in calves.


Treatment of benign prostatic hyperplasia by phenol injection.


Correlation of potential and fiber type in extraocular muscle.


Human corneal endothelium. I. Normal morphology.


Studies of antilymphoblast globulin.

Studies of antilymphoblast globulin.


The corticosteroid intraocular pressure response: thyroid function and phenylthiourea taste test.


Surface localization of Escherichia coli 5'-nucleotidase by electron microscopy. The 5'-nucleotidase of Escherichia coli was shown to be located at the cell wall surface by histochemical techniques utilizing the deposition of inorganic phosphate. Penetration of the 5'-nucleotidase in the periplasmic space was seen only in cells treated with ethylenediaminetetraacetic acid (EDTA)-tris(hydroxymethyl)aminomethane (Tris). The 3'-nucleotidase of E. coli was also found to have a surface location, and periplasmic precipitation of inorganic phosphate was seen only after EDTA-Tris-sucrose exposure.


Staining of intercellular material in reaggregating chick liver and cartilage cells.


Spectral properties of hemospexin-heme. The Schumm test.


On alterations of myocardial lactic dehydrogenase isozyme by coronary lition.


Hepatitis virus and renal dialysis.

Hepatitis virus and renal dialysis.


Observations of small blood vessels in human nondiabetic and diabetic gingiva.


Future of postgraduate medical education.


Epidemiology of drug abuse.

Epidemiology of drug abuse.


Hazard of Vacu-Drain system.

Hazard of Vacu-Drain system.


Topical treatment of burns.

Topical treatment of burns.


Neurological disturbances and minor burns.


Heterotopic-bone formation in two males with the 47,XYY karyotype.


Another contaminant affecting serum-protein-bound-iodine.


Inheritance of chronic granulomatous disease.


Phenformin and ethyloestrenol for Raynaud's disease.


Intestinal methylation of folates.

Intestinal methylation of folates.


Public health in Latin-America.

Public health in Latin-America.


Serum immunoelectrophoresis in patients with Ewing's sarcoma.


Fibrin and renal disease.

Fibrin and renal disease.


The genetic factor in pernicious anaemia.


Plasma aminoacids and oral contraceptives.


Hypertension and the pill.

Hypertension and the pill.


ABO blood-groups in patients with septal defects.


Accumulations of phytanic acid in Refsum's disease.


Dipyridamole and rejection reactions.

Dipyridamole and rejection reactions.


Carbenicillin-resistant pseudomonas.

Carbenicillin-resistant pseudomonas.


Induction of tolerance in man to horse-IgG.


Lawrence Henry Morris.

Lawrence Henry Morris.


William Gordon Smith.

William Gordon Smith.


A simple method of relaxation.

A simple method of relaxation.


Treatment of essential hyperlipidaemia.

Treatment of essential hyperlipidaemia.


Verbal desensitisation in the treatment of bronchial asthma.


Multiple sclerosis in immigrant and native populations of Israel.


Polyunsaturated fatty acids and myocardial infarction. Follow-up of patients with aortoiliac and femoropopliteal atherosclerosis.


Cadmium content of cigarettes.

Cadmium content of cigarettes.


Association between elevated hepatic water-soluble protein-bound cadmium levels and chronic bronchitis and-or emphysema.


Effect of blood-bank storage on leucocyte function.


Does lithium depletion cause atherosclerotic heart-disease?


Relaxation on record.

Relaxation on record.


Renal-artery stenosis and hypertension.

Renal-artery stenosis and hypertension.


Urticaria.

Urticaria.


Oestrogen content of oral contraceptives.


Cadmium.

Cadmium.


St. Louis encephalitis.

St. Louis encephalitis.


Isolated trigeminal neuropathy.

Isolated trigeminal neuropathy.


Hyperbaric oxygen and senile psychosis.

Hyperbaric oxygen and senile psychosis.


Sharing the care of the elderly between community and hospital.


Dr. Watson's war wounds.

Dr. Watson's war wounds.


Ampicillin rashes.

Ampicillin rashes.


The emergency laboratory assay.

The emergency laboratory assay.


Decline in U. S. childhood leukaemia mortality.


Towards an improved medical curriculum.

Towards an improved medical curriculum.


L-asparaginase and blastogenesis.

L-asparaginase and blastogenesis.


Immunosuppressive action of L-asparaginase.


Phenylbutazone and pulmonary oedema.

Phenylbutazone and pulmonary oedema.


Atheroma in a transplanted heart.

Atheroma in a transplanted heart.


Health centres: facts and figures.

Health centres: facts and figures.


L-dopa for progressive supranuclear palsy.


Immunological enhancement of rat kidney grafts.


Glycosuria in alkaptonuria--a dilemma.

Glycosuria in alkaptonuria--a dilemma.


Anaphylactic reaction to A.L.G. after induction of tolerance.


Non-pulmonary tuberculosis.

Non-pulmonary tuberculosis.


Induced metabolic alkalosis in hepatic encephalopathy.


Immunoglobulin deficiency and polyploidy.


Drugs for typhoid fever.

Drugs for typhoid fever.


Treatment of early cancer of the breast.


Diabetes and coeliac disease.

Diabetes and coeliac disease.


Fenfluramine overdosage.

Fenfluramine overdosage.


ABO blood-groups in patients with septal defects.


Transmission of 47, XYY karyotype?

Transmission of 47, XYY karyotype?


Iodine-125 treatment for thyrotoxicosis.


Delirium induced by a combination of anti-arrhythmic drugs.


Oral contraceptives containing oestrogens.


Hepatic reaction to nitrofurantoin.

Hepatic reaction to nitrofurantoin.


Diagnosing rubella.

Diagnosing rubella.


An evaluation of the haemagglutination inhibition test as an aid to the diagnosis of rubella.


Nursing behind bars. 2. The surgical unit at Wormwood Scrubs.


Gavin goes to hospital.

Gavin goes to hospital.


Smog eye irritation: effect of air pollution on the tear protein pattern.


S.L.E.: a model for the study of immunology.


Immunoglobulin production: method for quantitatively detecting variant myeloma cells. Mouse myeloma cells in continuous culture were cloned in soft agar. The clones were assayed for their ability to synthesize heavy and light chains of gamma globulin by immunoprecipitation directly in the agar. A minor population secreting only light chains was identified. The two cell types were recloned and a low incidence of conversion of 7S to light-chain production was demonstrated. This technique can be used to isolate rare variants of cells secreting specific macromolecules.


Definition and objective for clinical practice of professional operating room nursing.


VIP's.

VIP's.


As I see it: O.R. education.

As I see it: O.R. education.


One-way ticket to never-never land.

One-way ticket to never-never land.


Mission improbable.

Mission improbable.


Member in the spotlight (Margaret Perdue).


Cardiac transplantation and the OR nurse.


The transplant nurse.

The transplant nurse.


OR nursing research.

OR nursing research.


A literature review.

A literature review.


Teacher unaware.

Teacher unaware.


REeport from headquarters...a meeting with AORN's executive director.


A message from the president.

A message from the president.


U. S. Public Health Service National Medical Audiovisual Center.


Biomedical communications service established at the dental school.


Why not a set of slides on nursing?

Why not a set of slides on nursing?


Nursing care of the cardiac surgery patient.


Controlled cord traction.

Controlled cord traction.


Evaluation of Silastic 616 as a liner for the mandibular denture for problem patients.


Prison dentistry in Pennsylvania.

Prison dentistry in Pennsylvania.


Early diagnosis of periodontal disease: radiographic examination.


Snuff. The habitual use of snuff thought to be a factor causing anterior overbite.


Governor names Deputy Secretary of Health.


A clinical evaluation of patients with periodontosis.


Get set children at Temple.

Get set children at Temple.


Enzymatic and chemical changes in human lymphocyte cultures.


The morphology of the lateral cervical nucleus in the hedgehog.


The molecular layer of the adult cat cerebellar cortex after lesion of the parallel fibers: an optic and electron microscope study.


Zinc iodide-osmium tetroxide impregnation of nerve terminals in the spinal cord.


Scleromyxoedema--a variant of lichen myxoedematosus (papular mucinosis).


Management of herpes zoster.

Management of herpes zoster.


Pregnancy and chlormadinone acetate.

Pregnancy and chlormadinone acetate.


Primary 'acquired hypogammaglobulinaemia': a suggested mode of inheritance.


Reflex sympathetic dystrophy. A clinical, histological, histochemical and experimental study.


A morphological study on the mechanism of diazoxide-hyperglycemia (clinical and experimental investigation).


Identification of absorbed protein films by exposure to antisera and water vapor.


Some negative contrast staining features of a protein from erythrocyte ghosts.


A case of leucine-induced hypoglycaemia.


Human skeletal muscle fibre type grouping and collateral re-innervation.


Bound iodine and binding protein.

Bound iodine and binding protein.


Evidence for a toxic substance of bacterial origin in the blood of irradiated mice.


Early experience effects upon cortical dendrites: a proposed model for development. We studied the effects of environmental stimulation on the development of rat cortical pyramidal cell synaptic loci (dendritic spines) and the number of such cells staining by the rapid Golgi technique. Stimulation three to five times a day from the day of birth increased the number of spines per micrometer in 8-day-old animals and increased the number of neurons stanining at 8 to 16 days of age. This effect of afferent input upon development of the dendritic spine may represent the neuroanatomical basis for the influence of early experience on subsequent behavior. The number of neurons staining by the rapid Golgi technique appears to be related to those that are functionally involved at the time of tissue preparation.


Changes in connective tissue in sarcoid granuloma: hyalin, paraamyloid and fibrinoid. Electron microscopic study of 11 cases.


Stability of immune serum globulin during storage: effects of prior heating.


Rapid clearance of Rh positive blood during experimental Rh immunisation.


Stability of immune serum globulin during storage: effects of modifications in the fractionation scheme.


Immunofixation electrophoresis: a technique for the study of protein polymorphism.


Efferent pathways of the optic tectum in the frog.


Mechanism of the formation of mast-cell granules. II. Cell-free model.


Mechanism of the formation of mast-cell granules. 3. Self-regulating system of granule formation.


An iron-alum method for elective demonstration of acid mucopolysaccharides. I.


Demonstration of acid mucopolysaccharides by benzidine reactions.


Teacher assessment of Project Hurdle.

Teacher assessment of Project Hurdle.


Antibody deficiency syndrome and autoimmune haemolytic anaemia in a boy with isolated IgM deficiency dysimmunoglobulinaemia type 5.


Mechanisms of ventricular arrhythmias associated with myocardial infarction.


Ventricular vulnerability during acute coronary occlusion.


Waldenström's macroglobulinemia with increased serum IgG levels treated with low doses of cyclophosphamide.


Fibrous and granulomatous compartments in the otosclerotic focus.


Cyclical changes in nasal resistance.

Cyclical changes in nasal resistance.


Serum immunoglobulin levels in twins.

Serum immunoglobulin levels in twins.


Immunoglobulin analysis in families of macroglobulinaemia patients.


Immunoglobulin-containing cells in the liver.


Structure and function of identified nerve cells in the crayfish.


Fungicides in perspective.

Fungicides in perspective.


Can the brain be improved?

Can the brain be improved?


Anaphylactic reaction in the cat following intraventricular and intravenous injections of antigen.


The sheathed flagellum of Pseudomonas stizolobii.


Anergy, dysimmunoglobulinemia, and unexplained inflammation. A new therapeutic approach with a chemically defined diet.


Separation of human serum-alkaline-phosphatase isoenzymes by polyacrylamide gel electrophoresis.


Catecholamines and myocardial infarction.


Hospital milk kitchen.

Hospital milk kitchen.


Estimating drug-dosage regimens.

Estimating drug-dosage regimens.


The omohyoid syndrome.

The omohyoid syndrome.


Testicular endocrine function in males with Nooman's syndrome.


Inhibition by sympathomimetic amines of histamine release by antigen in passively sensitized human lung.


Refsum's disease: defective oxidation of phytanic acid in tissue cultures derived from homozygotes and heterozygotes.


Some biochemical and serological aspects of primate evolution.


Fatty liver in kwashiorkor.

Fatty liver in kwashiorkor.


Blood-fibrinolysis and activity of rheumatoid arthritis.


Malignancy and mortality in subacute rheumatoid arthritis in old age.


Immunoglobulins in the serum and mucus of the plaice (Pleuronectes platessa).


Isolation of human beta1A-globulin by modern techniques. 1. Human beta(1A)-globulin was isolated from serum by precipitation with ammonium sulphate, gel filtration and electrophoresis in polyacrylamide gel. 2. The product was found by ultracentrifugation, analytical electrophoresis in polyacrylamide gel and two-dimensional immunoelectrophoresis to be of satisfactory quality for further study. 3. The amino acid composition of beta(1A)-globulin was determined. 4. In ordinary dilute buffers near neutrality, beta(1A)-globulin had S(0) (20,w) 6.42s and M 131 000, but some reversible aggregation occurred at lower pH. In neutral 6m-guanidine hydrochloride the molecular weight was not measurably different from that in dilute buffer.


The effect of inhibitors on the formation of phosphoenolpyruvate by rat liver mitochondria. 1. Rat liver mitochondria oxidizing malate produce PEP (phosphoenolpyruvate) without the addition of ATP or other nucleotides. 2. The addition of oligomycin in the presence of 2,4-dinitrophenol did not abolish PEP formation and in some instances stimulated its formation. 3. Formation of PEP was inhibited by arsenate. 4. Arsenite decreased PEP formation and caused accumulation of pyruvate. 5. Added GTP and ITP had no effect on PEP formation. 6. PEP formed from malate in the presence of GTP and labelled P(i) had a specific radioactivity approximately the same as the P(i) with no contribution from the phosphate of the added GTP. 7. There was no parallelism between the effects of inhibitors on PEP formation from malate and their effects on the assayed activity of PEP carboxykinase. 8. In a direct comparison it was shown that the PEP carboxykinase content of mitochondria was insufficient to account for the PEP formation from malate. 9. Consideration of the kinetic characteristics of PEP carboxykinase and mitochondrial content of oxaloacetate and GTP show that this enzyme cannot account for the PEP formed from malate by mitochondria.


A simple method for staining and counting isolated adipose tissue fat cells.


Phosphoprotein synthesis in epidermis during acantholysis.


Excretion of pigeon serum proteins in pigeon droppings.


The dentato-olivary pathway. Somatotopic relationship between the dentate nucleus and the contralateral inferior olive.


Selective and nonselective susceptibility of muscle fiber types. A new approach to human neuromuscular diseases.


The effect of rifamycin on RNA synthesis in the rat liver mitochondria.


Herman Boerhaave, 1668-1738.

Herman Boerhaave, 1668-1738.


The use of snail neurons in neurophysiological studies.


The specificity and functional role of individual cells in a simple central nervous system.


Carcinogenic nitrogen compounds. LXVII. 6-substituted derivatives of 4,10-diazachrysene.


The structure of the collagen fibril.

The structure of the collagen fibril.


DNA polymerase activity as an index of lymphocyte stimulation: studies in Down's syndrome. The ability of peripheral blood lymphocytes to respond to phytohemagglutinin (PHA) in vitro was studied in patients with Down's syndrome. The response was measured by the increase in DNA polymerase activity and the rate of incorporation of tritiated thymidine by the cultured lymphocytes. These activities were significantly lower in PHA-stimulated lymphocytes from patients with Down's syndrome compared with age- and sex-matched, mentally retarded patients without Down's syndrome from the same institution and the normal healthy volunteers. The impairment in response to PHA does not seem to be related to the presence of Australia antigen in patients with Down's syndrome or to institutionalization itself. In contrast to DNA polymerase activity and thymidine-(3)H uptake, there was no significant difference in the percentage of blast transformation in the three groups studied. The poor response of the lymphocytes from patients with Down's syndrome to a mitogenic stimulus could reflect an impairment of cellular immune functions in these patients which may be one of the factors contributing to the vulnerability of these patients to repeated or persistent infections.


Immunoglobulin synthesis by salivary gland lymphoid cells in Sjögren's syndrome. The synthesis of immunoglobulins by cells infiltrating the labial salivary glands has been studied by radioimmunoelectrophoresis in 20 patients with Sjögren's syndrome (SS) and in 14 control patients with related disorders. The patients with SS were producing significantly greater quantities of IgG, IgM, and IgA. Synthesis of IgG and IgM correlated with the degree of lymphoid infiltration but not with serum immunoglobulin concentration. Patients with SS and rheumatoid arthritis (RA) showed greater synthesis of IgG and IgM than those with uncomplicated RA. The only extensive lymphoid infiltration was seen in patients with SS. One patient with SS and primary macroglobulinemia was synthesizing the paraprotein in the lip biopsy as well as in the bone marrow. These results establish the immunologic competence of the infiltrating lymphoid cells and suggest their origin from an extrasalivary source.


Disposal of plasma heme in normal man and patients with intravascular hemolysis. The clearance of plasma protein-bound heme, its sites of removal, and the reutilization of hemeiron were studied by radioisotopic techniques in normal human subjects and in patients with intravascular hemolysis. In normal subjects, injected heme-(59)Fe was bound immediately by albumin and the beta(1)-globulin, hemopexin. Its clearance from the plasma was descr bed by a single exponential equation, and the half-life in plasma was 7-8 hr. Removal was largely by the liver. Iron reutilization began promptly, and half the injected heme-iron was incorporated into circulating red cells within one cell life-span. In patients with intravascular hemolysis, hemopexin was depleted, and injected heme was bound solely to albumin. Plasma clearance was described by a double exponential equation of the form: y = Ae(-k1t) + Be(-k2t). The half-lives of the two components averaged 3.9 and 22.2 hr, respectively. Removal was by the liver in at least some of the patients, and iron reutilization was variable, depending on the state of body iron stores. When hemopex'n was depleted in a normal subject by repeated heme injection, clearance mimicked that observed in the patients.


Functional morphology and histochemistry of structural proteins of the genital cone of Cooperia punctata (von Linstow, 1907) Ransom, 1907, a nematode parasite of ruminants.


Insulin secretion following myocardial infarction with particular respect to the pathogenesis of cardiogenic shock.


Nursing posture after acute myocardial infarction.


Risks of ischaemic heart-disease in familial hyperlipoproteinaemic states.


Post-exercise ketosis.

Post-exercise ketosis.


Use of human-placental-lactogen radioimmunoassay to predict outcome in cases of threatened abortion.


Effect of synalbumin of lipolysis.

Effect of synalbumin of lipolysis.


Radioimmunoassay of gastrin in human serum.


Fenfluramine in obese patients on various antihypertensive drugs. Double-blind controlled trial.


Hair-root adaptation to marasmus in Andean Indian children.


Inhibition of drug metabolism by chloramphenicol.


Amenorrhoea and galactorrhoea associated with hypothyroidism.


Pharyngeal leeches.

Pharyngeal leeches.


Management of penicillamine nephropathy in Wilson's disease: a new chelating agent.


Thigh cannula: a femoral saphenous cannula for use in maintenance haemodialysis.


Human placental lactogen.

Human placental lactogen.


Man and his pesticides.

Man and his pesticides.


Death penalty and violent crime.

Death penalty and violent crime.


Sterility of eye-drops.

Sterility of eye-drops.


Infection and serum-lipids.

Infection and serum-lipids.


Controlling foot-and-mouth disease.

Controlling foot-and-mouth disease.


Test-battery to measure ageing-rate in man.


Rabies in England.

Rabies in England.


Dietary prevention of atherosclerosis.

Dietary prevention of atherosclerosis.


Aorto-iliac haemodynamics in renal transplantation.


Hodgkin's disease: a possible experimental model in rats.


Prevention of bacterial endocarditis.

Prevention of bacterial endocarditis.


Fenfluramine overdosage.

Fenfluramine overdosage.


Neurological disturbances following minor burns.


Peritoneal dialysis in maple syrup urine disease.


Rifamycin antibiotics in chronic bronchitis.


Haemolytic-uraemic syndrome: failure to demonstrate circulating endotoxin.


Dental anaesthesia.

Dental anaesthesia.


Two children with diabetes insipidus and diabetes mellitus.


Gentamicin-resistant Staphylococcus aureus.


Prevention and treatment of allergic reactions.


N.B.T. tests in premature infants.

N.B.T. tests in premature infants.


Simian herpesvirus SA8 from a baboon.

Simian herpesvirus SA8 from a baboon.


Jejunal absorption of aminoacids in nutritional rickets.


Homocystinuria and organic aciduria in a patient with vitamin-B12 deficiency.


Frank Wild Holdsworth.

Frank Wild Holdsworth.


Edward Lincoln Williams.

Edward Lincoln Williams.


Haemophilus influenzae meningitis in an adult. A study of bactericidal antibodies and immunoglobulins.


The occurrence of blood group substances A and B in proprietary gamma globulin of placental origin. Rep No 807.


Human serum anti-globulins and immunization. Rep No 804.


New staining technique for spleen nodules. A comparison of Do's. NRDL-TR-69-5.


Slow reacting substance of anaphylaxis.

Slow reacting substance of anaphylaxis.


Enzymic and histochemical changes in fast and slow muscles after cross innervation.


Prevention of the "failure syndrome" in the primary grades: implications for intervention.


The effect of clomiphene citrate in anosmic hypogonadotrophism.


Cardiac arrhythmias resulting from tracheal suctioning.


The measurement and significance of the urinary flow rate.


Immunofluorescent antibody studies in dermatitis herpetiformis.


EEG and cerebral blood flow following cortical application of strychnine and mescaline.


TSH and dibutyryl-cyclic-AMP stimulation of hormone release from rat thyroid glands in vitro.


Effect of progesterone and other steroids on PMS-induced ovulation in the immature rat.


Immunorheophoresis.

Immunorheophoresis.


The immunoglobulins of the dog. II. The immunoglobulins of canine secretions.


Indirect immunoenzyme techniques for the intracellular detection of antigens.


Microheterogeneity of L-amino acid oxidase. Separation of multiple components by polyacrylamide gel electrofucusing.


Impaired lymphocyte transformation in ataxia-telangiectasia in part due to a plasma inhibitory factor.


The production in chickens of antibody by spontaneous escape following immunologic tolerance.


Effect of chlormadinone on amount of human cervical mucus and its glycogen content.


The reaction of immunoglobulin-coated bentonite and radioiodinated antigen as a basis for antibody detection and antigen binding.


Immunoglobulins, antibodies and the bursa of Fabricus: induction of agammaglobulinemia and the loss of all antibody-forming capacity by hormonal bursectomy.


Antiphagocytic effects of staphylococcal protein A.


Elevated IgG antiglobulins in patients with seronegative rheumatoid arthritis.


Measurement of gastric emptying time with a gamma camera.


Small-intestinal lesion of chronic diarrhoea and marasmus in Iran.


An investigation of traveller's diarrhoea.


Diagnosis of intrauterine disease by sponge biopsy technique.


Simple method for increasing reliability in diagnosis of urinary infection.


Mr. Crossman at a crossroads.

Mr. Crossman at a crossroads.


Genetics of schizophrenia.

Genetics of schizophrenia.


Cell-mediated immunity in hay-fever.

Cell-mediated immunity in hay-fever.


Travellers' diarrhoea.

Travellers' diarrhoea.


Syphilis and hepatic cirrhosis.

Syphilis and hepatic cirrhosis.


Cell cytoplasm and mitosis.

Cell cytoplasm and mitosis.


Psychiatric services and the young offender.


Influenza.

Influenza.


The use and abuses of drugs in psychiatry.


Teaching of medicine in the London schools.


Cyanocobalamin: a case for withdrawal.

Cyanocobalamin: a case for withdrawal.


Contamination of blood stored in plastic packs.


Oral contraceptives and low antithrombin-3 activity.


Cadmium.

Cadmium.


In prison.

In prison.


Ethanol infusions.

Ethanol infusions.


Function of the transplanted thymus.

Function of the transplanted thymus.


Creatinine excretion.

Creatinine excretion.


Anaesthetics: time to delegate?

Anaesthetics: time to delegate?


Skin-grafting leg ulcers.

Skin-grafting leg ulcers.


Occult blood in faeces.

Occult blood in faeces.


An appeal to doctors.

An appeal to doctors.


Pseudomonas in ventilators.

Pseudomonas in ventilators.


Combined surgery and chemotherapy for carcinoma of bronchus.


Abnormal forms of Factor X.

Abnormal forms of Factor X.


Plasma-lignocaine levels after intravenous and intramuscular injection.


Fenfluramine overdosage.

Fenfluramine overdosage.


Primary sex-ratio and size of family.

Primary sex-ratio and size of family.


Analgesic abuse and tumours of the renal pelvis.


Mycotoxins in aplastic and proliferative blood-diseases.


Gonococcal arthritis after treatment of gonorrhoea.


Arm circumference in children.

Arm circumference in children.


Efficient, cheap, and simple electrodes for E.C.G. monitoring.


Fatal case of agranulocytosis due to chlorpromazine.


Odd inguinal swelling.

Odd inguinal swelling.


Roney Moore Patterson.

Roney Moore Patterson.


Patrick Wensley Clarkson.

Patrick Wensley Clarkson.


Importance of pneumococcal typing in pneumonia.


Proinsulin content of pancreas in human fetuses of healthy mothers.


Fusidic acid and lincomycin therapy in staphylococcal infections in cystic fibrosis.


Oesophageal cancer in Africa.

Oesophageal cancer in Africa.


Nephrotic syndrome and spherocytosis.

Nephrotic syndrome and spherocytosis.


Intestinal perforation, exchange transfusion, and P.V.C.


Peptide formation in the presence of linear or cyclic polyphosphates.


Anti-nucleic acid specificites of mouse myeloma immunoglobulins.


Lead accumulation in roadside soil and grass.


Hormonal iodine determinations in thyroid disorders.


Possible postganglionic adrenergic effect of angiotensin in the isolated perfused cat intestinal segment.


The effect of glucose injections on the 24 hour urinary output of histamine in normal female rats.


On the chemical components of the stink of "Chrysocoris stolli" Wolf. (Heteroptera: Pentatomidae: Insecta).


Action of some sugars on the secretion of chitinase.


Effects of alkalemia on myocardial performance.


Effects of imidazole and cyanide upon rat adipose tissue lipolysis.


Biosynthesis of fatty acids and cholesterol in a fresh-water carp, "Scardinius erythrophthalmus" from sodium acetate-1-14C.


Protein nutrition of "Tenebrio molitor" L. IX. Replacement caseins for the reference diet and a comparison of the nutritional values of various lactalbumins and lactalbumin hydrolysates.


Chemical differences in the blood of yellow and silver phases of the european eel ("Anguilla anguilla" L.).


Blockade of membrane calcium fluxes by lanthanum in relation to vascular smooth muscle contractility.


Synthesis of macromolecules in epithelial cells of the cultured amphibian lens. 3. Involvement of protein synthesis in mitotic activation.


Simultaneous sensitization to metabolic and cardiovascular effects of noradrenaline.


Protein nutrition of "Tenebrio molitor" L. X. Improvement of the nutritional value of lactalbumin by supplementation with amino acids.


Phosphatide metabolism in the axis of mung bead seedlings "Phaseolus aureus".


Lacticodehydrogenase release from perfused rat heart under the effect of abnormal media.


The changes of the binding properties of plasma proteins to thyroxine as measured by the thyroxine-precipitation test.


Plasma thyrotrophin levels in thyroid disease and effect of treatment.


Pituitary and ovarian function in women on continuous low dose progestogens; effect of chlormadinone acetate and norethisterone.


Metaplasia of cartilage into bone. A study by slain historadiography.


A rapid method for lipoprotein electrophoresis using cellulose acetate as support medium.


Glucose, insulin, and growth hormone studies in long-term users of oral contraceptives.


Rho(D) immune globulin: a double blind clinical trial.


Effect of sympathetic nerve activity on labeling and release of histamine in the cat.


Reversible dissociation of ferritin and its subunits in vitro.


Quantitation of secretory immunoglobulin A in chronic pulmonary disease.


Clinical evaluation of Rho(D) immune globulin (human) in Canada. -During 1966, clinical trials were conducted in three Canadian centres to determine the safety and efficacy of Rh(0)(D) immune globulin (human) in preventing isoimmunization by the Rh(0)(D) antigen in Rh-negative women delivering ABO-compatible Rh-positive infants.The candidates were randomly divided into control and treated groups; the treated mothers received an intramuscular injection of 300 mug. of anti-Rh(0)(D) within 72 hours of delivery. Follow-up antibody screening tests were conducted on the sera of all patients six to nine months post partum.Of the 175 control patients, 11 or 6.2% became actively immunized to the Rh antigen, whereas complete protection against maternal Rh immunization was observed in the 191 treated patients.


Interaction between signal and noise in evoked potentials.


Susceptibility to audiogenic seizure induced by thiosemicarbazide.


A system designed to extract information on seizures.


An alternative to the time series method for the analysis of averaged evoked potentials.


EEG correlates of learning in sleep experiments with humans.


Factoring analysis of the evoked response, a form of data reduction.


A non-parametric method of determining general EEG changes due to the administration of drugs.


EEG patterns with minimal alterations in consciousness in man.


Detection of magnetic fields outside the human head produced by alpha rhythm currents.


A system for sensing and transmitting EEG.


WAIS IQ as related to EEG rrequency scores.


The role of EEG in the diagnosis of coma: Introduction and technical problems.


Mass lesions and vascular disease.

Mass lesions and vascular disease.


The electroencephalogram in the investigation of metabolic comas.


The EEG in anoxic coma.

The EEG in anoxic coma.


Coma and seizures.

Coma and seizures.


The EEG in coma-toxic causes.

The EEG in coma-toxic causes.


Hippocampal EEG correlates of behavior.

Hippocampal EEG correlates of behavior.


Inter-individual differences in hippocampal theta activity during habituation.


A comparative sleep study of two Cercopithecinae.


Evoked cortical responses to checkerboard patterns: effect of check-size as a function of visual acuity.


Developmental study of photic evoked responses in premature infants.


Septum after-discharge effects upon cortical photic-evoked responses.


An attempt to analyze multi-unit recordings.


A discriminator and integrator device for multi-unit neural activity analysis.


Thalamic stereo-encephalography.

Thalamic stereo-encephalography.


Neuro-physio-pathological comments on stereotaxic operations for intractable chronic pain.


Functional stereotaxic exploration (SEEG) of epilepsy.


Presentation and practical value of a programme of information processing in electroencephalography.


EEG study of physiological sleep by spectral analysis in two children.


Unusual late components of the averaged sensory evoked response and multisensory disturbances.


Rheo- and arteriographic correlations in cervical arterial pathology.


Deprivation of REM sleep in chronic schizophrenic patients.


A study of jactatio capitis during night sleep.


EEG and visual deprivation.

EEG and visual deprivation.


Visual evoked potentials in sighted and partially sighted children.


The EEG of acute necrotizing encephalitis.


Partial attacks facilitated by peripheral stimulation: a polygraphic record in one case.


Problems raised by cerebral electrical silence in toxicology with reference to one observation during an acute intoxication.


Findings on the regional cerebral circulatory deficit in cerebral vascular pathology (a recent technique by inhalation and external counting of a radioactive gas).


Electromyographic study of extension of the middle finger.


Electromyographic investigation of serratus magnus.


Modifications of the curve of recruitment of the Hoffman reflex by vibration or sinusoidal stretching of the sural triceps.


Polysynaptic and monosynaptic reflexes evoked in the short head of the femoral biceps in normal man.


The value of stimulus detection for long periods in the diagnosis of spasmophilia.


Clinical and electroencephalographic correlates in patients hospitalized with psychiatric disorders.


Special characteristics of EEG activity accompanying deep spiking in a patient with schizophrenia.


Electroencephalogram in patients with palatal myoclonus.


Somato-sensory evoked potentials in patients with unilateral cerebral lesions.


Selective inhibition of patterned vision in amblyopia ex anopsia.


The cerebral somato-sensory response induced by passive joint movement.


The CNV and the "late positive wave"--two sides of the same coin.


Evoked response variations in relation to the preceeding EEG.


Evoked potential components and paired flash measures of visual reactivity cycles.


Morning-evening differences in the EEG and cerebral evoked response; relations to 17 hydroxycorticosteroid levels.


Enhancing evoked responses by optimum a posteriori filtering.


Paroxysmal electroencephalographic abnormalities experimentally induced by electrolyte alterations.


Metrazol-valium combination for EEG activation.


Acute effects of Dilantin on the EEG of epileptic patients: a quantitative study.


EEG's during open heart surgery.

EEG's during open heart surgery.


"Small sharp spikes" (SSS): electroencephalographic characteristics and clinical significance.


Depth EEG findings in epileptics with generalized spike-wave complexes.


Epileptiform discharges in the various stages of sleep.


Automatic processing of sleep EEG's.

Automatic processing of sleep EEG's.


Relationships of cortical glial cell depolarizations to electrocortical surface wave activity.


Inhibitory mechanisms during tonic-clonic seizures.


The influence of cortical steady potentials on evoked potentials and neuron activity.


Changes in action potential forms during cell penetration in tissue culture.


Hemi-cerveau isolé: a model for study of spontaneous EEG activity.


Neurophysiological and psychological studies of electrically induced seizures.


Thalamic somato-sensory evoked potential in Parkinsonian patients--corelation with unit responses and thalamic stimulation.


Evoked responses and neuronal activity.

Evoked responses and neuronal activity.


Maturation of the contingent negative variation.


Computer analysis of the EEG during sleep deprivation in the monkey.


Convulsive excitability in partially deafferented cortex.


Mitosis in Aspergillus nidulans.

Mitosis in Aspergillus nidulans.


Observations on the central pair of microtubules from the cilia of Tetrahymena pyriformis.


Thyrotoxicosis and collagen-like disease in three sisters of American Indian extraction.


The Achilles reflex time in thyroid disorders.


Granuloma inguinale. A clinical, histological and ultrastructural study.


Traffic pollution and mental efficecy.

Traffic pollution and mental efficecy.


Synthetic polypeptides related to corticotrophin acting as histamine liberators.


Chronic neutropenia and abnormal cellular immunity in cartilage-hair hypoplasia.


Impaired phagocytosis by peripheral blood granulocytes in systemic lupus erythematosus.


Atmospheric photochemistry.

Atmospheric photochemistry.


Annual oration on evaluation of methods of treatment of cancer.


On the development of bone marrow innervation in new-born rats as studied with silver impregnation and electron microscopy.


Organ transplantation. The present position and future prospects of organ transplantation.


Reactive dyes as vital indicators of bone growth.


Regeneration of synapses in vitro.

Regeneration of synapses in vitro.


Leishmania donovani: antibody response to chicken ovalbumin by infected golden hamsters.


Protective action of passively transferred immune serum and immunoglobulin fractions against tissue invasive stages of the dwarf tapeworm, Hymenolepis nana.


Catabolite repression in antibiotic-limited streptomycin-dependent Escherichia coli B.


Interactions between gamma-globulins and adenovirus virions.


Action of uranyl acetate on the murein of Spirllum serpens.


Effects of antibiotics on bacterial lysis and intracellular ribosomes.


Synthetic myosin filaments from vertebrate smooth muscle.


Regulation of protein synthesis directed by coliphage MS2 RNA. I. Phage protein and RNA synthesis in cells infected with suppressible mutants.


Effect of prednisolone on anaphylactic reaction of peritoneal mast cells of the rat.


Localization of polysaccharides, -SH and SS groups in the oocytes of Anabas scandens (Cuvier).


Studies on morphology, nucleic acids and polysaccharides of mesencephalic trigeminal neurons in developing rat.


An unusual ultrastructural association of smooth membranes and glycogen particles: the glycogen body.


An unusual immunoproliferative disorder.


Transrectal prostatography: its use in prostatic hypertrophy.


[Heterogeneity of the thyroid gland and its impact on the interpretation of radioiodine tracer studies].


Acid alcoholic brilliant cresyl blue stain for gastric and other mucins.


Differential staining of catecholamines, 5-hydroxytryptamine and related compounds in aldehyde-fixed tissues.


The survival rate of patients with advanced rectal cancer.


Some recent advances in the clinical pathology of infectious mononucleosis.


The binding of lithium carmine to alpha2-macroglobulin.


Instructions for preparation of slide material for projection.


A comparison of serum immunoglobulin concentrations in sarcoidosis and tuberculosis.


Microradiography and histology of decalcified human teeth following experimental intrusion; with emphasis on resorption.


Vascular lesions in women taking oral contraceptives.


Rheumatoid arthritis, dysproteinemic arthropathy, and paraproteinemia.


Procainamide-induced serologic changes in asymptomatic patients.


Experimental murine amyloid. 3. Amyloidosis induced with endotoxins.


Transcutaneous measurement of arterial flow velocity with a Doppler flowmeter in normal subjects and in patients with cardiac dysfunction.


The spatial characteristics of atrial activation in ventriculo-atrial excitation.


Elevated levels of gamma-E (IgE) in conditions other than classical allergy.


Studies on the site of action of oral contraceptive steroids. II. Plasma LH and FSH levels after administration of antifertility steroids and LH-releasing hormone(LH-RH).


A tri-axial classification of mental disorders in childhood. An international study.


A serologic response in human pseudomonas infection.


Immunoglobulin synthesis in lower urinary tract infection.


The role of polymorphonuclear leukocytes in the lesion caused by the venom of the brown spider, Loxosceles reclusa.


Effect of combined oestrogen-progestogen oral contraceptives on serum-levels of alpha 2-macroglobulin, transferrin, albumin, and IgG.


Cryofibrinogenaemia in women using oral contraceptives.


Prognosis of chronic persistent hepatitis.


Metabolic and clinical effects of glibenclamide.


Toxicity of folic acid given in pharmacological doses to healthy volunteers.


Enzyme inhibition by lead under normal urban conditions.


Dissecting microscopy of rectal mucosa.

Dissecting microscopy of rectal mucosa.


Superior intelligence in recessively inherited torsion dystonia.


Reduced muscle alpha-glucosidase (acid-maltase) activity in hypothyroid myopathy.


Antitrypsin deficiency in chronic obstructive lung disease.


Mental health services.

Mental health services.


Plasma-proteins and oral contraceptives.


Protein-binding of drugs.

Protein-binding of drugs.


Student casualties.

Student casualties.


Coliform organisms in the pharynx.

Coliform organisms in the pharynx.


Natural history of cerebrovascular disease.


Misdirected money-raising.

Misdirected money-raising.


Repeated stimulation of the reticuloendothelial system and the development of plasma-cell dyscrasias.


Appeal to doctors.

Appeal to doctors.


Thyrotoxicosis in a father and two sons.


Treatment of severe cutaneous herpes.

Treatment of severe cutaneous herpes.


Creatinine excretion.

Creatinine excretion.


Asymptomatic malaria.

Asymptomatic malaria.


Antenatal diagnosis and treatment of the adrenogenital syndrome.


Antenatal diagnosis of the adrenogenital syndrome.


A chemical method for the antenatal diagnosis of mucopolysaccharidoses.


A technique for culturing cells from amniotic fluid.


Hypertension during imipramine treatment.


Buying hospital furniture.

Buying hospital furniture.


Tegretol for pain in the Guillain-Barré syndrome.


Bleeding abdominal stomal varices.

Bleeding abdominal stomal varices.


The Committee and the pill.

The Committee and the pill.


Immunological enhancement of rat kidney grafts.


Computers and priorities.

Computers and priorities.


Miliary tuberculosis, tuberculosis of ribs, and heroin addiction.


Hospital staffing structure.

Hospital staffing structure.


Affective illness and cyclic-A.M.P. excretion.


Setting multiple-choice questions.

Setting multiple-choice questions.


Serum alpha-1-fetoprotein in liver disease.


Microsomal-enzyme stimulation in man by B.H.T.


Occult blood in faeces.

Occult blood in faeces.


Vasectomy and A. I.H.

Vasectomy and A. I.H.


Congenital malformations of the limbs.

Congenital malformations of the limbs.


Death penalty.

Death penalty.


Fetal audiometry.

Fetal audiometry.


Viruses and Hodgkin's disease.

Viruses and Hodgkin's disease.


Artists and photographers.

Artists and photographers.


Bone abnormalities and XXYY.

Bone abnormalities and XXYY.


Oral lignocaine.

Oral lignocaine.


The changing British drug scene.

The changing British drug scene.


Inheritance of Down's syndrome: fact and theory.


Subluxation of the sacroiliac joint.

Subluxation of the sacroiliac joint.


Dietary prevention of atherosclerosis.

Dietary prevention of atherosclerosis.


Anaesthetics: time to delegate?

Anaesthetics: time to delegate?


Anaesthesia in the dental surgery.

Anaesthesia in the dental surgery.


Invalidensport.

Invalidensport.


Duncan Macmillan.

Duncan Macmillan.


Cardiac transplantation, coronary atheroma, and ischaemic heart-disease.


Cytological features of three fiber types in human striated muscle.


Electron microscopy of human coronal dentine. A methodological study with emphasis on the "aspiration" of odontoblast nuclei.


A stereotaxic atlas of the brain of the marmoset (Hapale jacchus).


Some histochemical characteristics of tracheobronchial tree and pulmonary neoplasms.


The excretion of chlorinated hydrocarbon insecticides in human mother's milk.


Changes in histochemical staining of brain tumor blood vessels associated with increasing malignancy.


Ammoniacal silver staining of degenerating axons.


Infectious hepatitis. Gamma-globulin prophylaxis in a community outbreak.


The perirenal P sign: a new roentgenogram index to the cause and treatment of urinary ascites in babies.


Comparison of three methods for human growth hormone immuno-assay.


Reaction in vitro of synthetic oxytocin and lysine-vasopressin with the pseudoisocyaninchloride technique used for the demonstration of neurohypophysial neurosecretory material.


Quintuplet pregnancy diagnosed and assessed by ultrasonic compound scanning.


Hepatic allografts and xenografts in primates.


Proline-hydroxylase activity in human blood.


Spontaneous remission of the defect in urinary acidification after cadaver kidney homotransplantation.


Renal biopsy in clinical management of renal transplantation. A light-microscopy study.


Cutaneous hypersensitivity reactions to autologous extracts of malignant melanoma cells.


Detection of bacteriuria at room-temperature.


Chromosome studies on 3500 newborn male infants.


Servo regulation of environmental oxygen concentration in neonatal period.


A double-action button crusher.

A double-action button crusher.


Rubella vaccines.

Rubella vaccines.


Sex, intersex, and the law.

Sex, intersex, and the law.


The image of clinical pharmacology.

The image of clinical pharmacology.


Oxygen therapy.

Oxygen therapy.


Persistence of treponemes and the infectivity test in syphilis.


New light on Creutzfeldt-Jakob disease.

New light on Creutzfeldt-Jakob disease.


Brucellosis.

Brucellosis.


Emergency ward.

Emergency ward.


Who benefits?

Who benefits?


Chance, mental illness, and crime.

Chance, mental illness, and crime.


Accidents at work.

Accidents at work.


Inflation in the laboratory.

Inflation in the laboratory.


John, 17 months.

John, 17 months.


Immunoresistant tetraploid lymphoma cells.


Vasectomy.

Vasectomy.


Another hazard of smoking?

Another hazard of smoking?


Deficiency.

Deficiency.


Hepatitis-associated antigen in chronic liver disease.


Serum alpha 1-fetoprotein in liver disease.


Cell cytoplasm and mitosis.

Cell cytoplasm and mitosis.


Misdirected money-raising.

Misdirected money-raising.


18-trisomy syndrome in a girl of eight.

18-trisomy syndrome in a girl of eight.


Oral contraceptives and low antithrombin-3 activity.


Changing British drug scene.

Changing British drug scene.


Calcium cyclamate and renal tubular acidosis.


Creatinine excretion.

Creatinine excretion.


Can E.B. virus affect the fetus?

Can E.B. virus affect the fetus?


Unwanted pregnancies.

Unwanted pregnancies.


Sharing the care of the elderly.

Sharing the care of the elderly.


Asystole during pacemaker operations.

Asystole during pacemaker operations.


Unusual cause of palatal pain.

Unusual cause of palatal pain.


New biopsy needle.

New biopsy needle.


Travellers' diarrhea.

Travellers' diarrhea.


The eye and measurement of ageing-rate.

The eye and measurement of ageing-rate.


Dangers of decimals.

Dangers of decimals.


Sterility of eye-drops.

Sterility of eye-drops.


Press and profession.

Press and profession.


Growth of phenylketonuric children on chemically defined diets.


Ethel Browning. M.D. L'pool.

Ethel Browning. M.D. L'pool.


Experimental reproduction of intracellular granules from heparin and neomycin in cultivated normal and leukaemic leucocytes.


Immunisation of schoolchildren with rubella (RA27-3) vaccine. Intranasal and subcutaneous administration.


Problems in intraarterial chemotherapy. I. Drug dilution.


Now and in the future.

Now and in the future.


Don't play our requiem.

Don't play our requiem.


The effect of non-paralytic doses of D-tubocurarine on individual motor end-plates in man, studied with a new electrophysiological method.


A correlation of EEG, reticular multiple unit activity and gross behavior following various antidepressant agents in the cat. IV.


Effects of antidepressant drugs on wakefulness and sleep in the cat.


Primary auditory evoked potentials after section of brachium of the inferior colliculus.


Effects of lowered body temperature on hyperoxic seizures.


A test of an "efferent model" of the function of inferotemporal cortex in visual discrimination.


The Klein-Levin syndrome with intermittent abnormality in the EEG.


The EEG in a case of periodic hypersomnia.


Abnormal connections between skeletal muscle fibers.


Micro-electrode tip position marking in nervous tissue: a new dye method.


A stereotaxic frame assembly for investigating the cat auditory system.


Mechanisms of origin of the EEG.

Mechanisms of origin of the EEG.


Mixing excitatory and inhibitory components in poly-synaptic post-synaptic potentials.


The action of raised CO2 pressure on the excitability of spinal motorneurones.


Experimental single-cell investigations of a summatory excitatory picutre (with reference to genesis of the EEG).


Findings in regard to spread of excitation in spinal motorneurones and motor cortex cells.


Cortical recruiting and desynchronization by stimulation of the putamen and pallidum of cats.


On inter-hemispheric transfer in "corpus callosum cats".


Optokinetic and vestibular ear nystagmus in rabbits.


Stimulation experiments on the tectum opticum of freely moving decorticate cats.


On extension of the diagnostic power of the EEG by micromotor tone recording.


Results of micromotor tone research in the clinical neurological field.


Electronic analysis of EEG and other curves.


EEG and cerebral circulation.

EEG and cerebral circulation.


Correlation between regional cerebral flow (rCBF) and EEG frequency spectrum.


On hyperventilation changes in the EEG and their relationships to blood gases, hydrogen-ion concentration and electrolytes.


On the development of the EEG in the course of treatment of diffuse cerebral vascular and atrophic processes.


Serial studies of cerebral vascular processes by means of interval analysis.


EEG changes in cerebral vascular occlusions. Differential diagnostic considerations.


Influence of hyperbaric oxygenation on the recovery of the rabbit brain after cerebral ischaemia.


EEG flattening and spinal reflex excitability.


The role of electroencephalography in resuscitation.


Experimental investigations on newborn and young kittens, especially on animals with chronic epileptogenic foci in different locations.


Neurophysiological and biochemical investigations on cats with epileptic seizures.


A twilight state or focal sensory attack?


The significance of extremely fast beta waves (less than 30c per sec) in conventional surface EEG in man.


Syndromes of hypochondriasis and the EEG.


Supplementary investigations on the question of the influence of hypothyroidism on the central nervous system.


The "trace alternant" of the sleeping EEG in full-term, premature and hypotrophic neonates.


Polygraphic recording in children with phenylketonuria.


Electroencephalographic manifestations of cerebral attacks and intellectual development in phenylketonuria.


Investigations on the genetics of photosensitivity.


Hypsarrhythmia, spike and wave variants and petit mal status in childhood.


Electrocerebral findings in closed head injuries in childhood.


The regulation of the heart rate during sleep.


Differential diagnostic applicability of the EEG in comatose patients.


The periodicity of erection during sleep in healthy men.


The behaviour of alpha rhythm under defined motor and pharmacological conditions.


Considerations on the relationship between alpha rhythm and so-called expectancy waves.


EEG changes under different conditions.

EEG changes under different conditions.


EEG frequency analysis in the examination of groups. A study of the EEG of old people.


Frequency analysis of the flat EEG.

Frequency analysis of the flat EEG.


Comparison of the Fourier and aperiodic interval analysis of EEG tracings.


Automatic recognition of pattern groups in the EEG.


Visual evoked potentials in epilepsy.

Visual evoked potentials in epilepsy.


Digital amplitude interval analysis. A new method of quantitative analysis of the EEG.


EEG analysis using the signal comparator procedure.


The possibilities of telemetry of physiological data.


EEG and reanimation.

EEG and reanimation.


EEG investigations in aircraft crews.

EEG investigations in aircraft crews.


EEG contributions to problems in industrial medicine.


Critical view on the possibility of using the rheoencephalogram in medico-aeronautical expertise.


Certain electroencephalographic aspects in accidental poisoning with Ecatox in children.


Electroencephalographic investigations of workers in a chemical coke plant.


The electroencephalogram in medico-legal assessment.


Clinico-electroencephalographic correlations in psychiatric expertise of juvenile delinquents.


Penicillin epilepsy in man.

Penicillin epilepsy in man.


A 7-year-old boy with akinetic mutism after cerebral contusion.


The value of electrophysiological investigations in the rehabilitation of former tuberculous patients.


The significance of EEG anomalies refractory to treatment in epileptic children.


Gammaencephalographic investigations in cerebral tumour diagnosis.


Motor, electrographic and vegetative reactivity to slight vestibular stimulation.


EEG aspects in craniostenosis.

EEG aspects in craniostenosis.


Electro-clinical considerations on some cases of van Bogaert's subacute leukoencephalitis.


A case of epilepsia partialis continua.

A case of epilepsia partialis continua.


The role of the central monamine oxidase systems in the determination of EEG alterations in Graves disease.


Polygraphic investigations of sleep in nocturnal ambulatory automatisms.


EEG investigations on the action of Chlordelazine, Oxypertin and Fluanxol in chronic schizophrenia.


Contributions to the EEG study of W. Y. 3498.


The significance of minor EEG abnormalities focal in the left temporal region.


EEG data in intracranial metastases.

EEG data in intracranial metastases.


The place and the importance of EEG and rheoencephalography in the pathology of the operated stomach.


ERG and EEG changes in Steinert myotonic dystrophy.


EEG study of hypophyseal dwarfism.

EEG study of hypophyseal dwarfism.


Clinical EEG and polygraphic investigations of sleep in children with simple enuresis or associated with other non-convulsive nocturnal episodic manifestations.


Electroencephalograms in meningitis.

Electroencephalograms in meningitis.


Cerebral electrical investigations in raised blood pressure in children and youths.


The applications of electromyography in stomatology.


Electromyography in the determination of certain aetiopathogenic aspects of scoliosis.


The EMG picture of diuretic therapy in hypothyroidism.


Study of the latency of the response in chronic tetany.


Study of conduction velocity in motor fibres of peripheral nerves in toxic polyneuritis produced by carbon disulphide.


Effects of noise in EEG latency changes in an auditory vigilance task.


The effects of suppressing the paradoxical phase of sleep on the metabolism of cerebral ammonia.


Induced depressant influences from the centrum medianum (Luys) upon the evoked activity of the amygdalo-hippocampal complex.


Transistorized neuro- and myostimulator with impulse memory.


EEG alterations in athletes in the barochamber at 5000m altitude.


Interaction between the stubstantia nigra and nucleus caudatus in evoking recruiting-like cortical responses.


Polygraphic method of investigation of the complex reactivity to slight caloric vestibular stimulation.


EEG in rabbits following glucose infusion. Simple quantitative analysis.


EEG investigations with micro-electrodes in the primary acoustic areas.


The transmission pathways of acoustic stimulation to the anterior sigmoid gyrus.


Electrocortical and autonomic balance induced by vegetative afferents.


The effects of chronic occipital epileptogenic lesions (cobalt-alumina) in Papio papio.


Correlations between electrophysiological activity from the human olfactory bulb and the subjective response to odoriferous stimuli.


Determining occupancy at various admission rates, lengths of stay.


Antiphagocytic effects of staphylococfcal protein A.


Fat embolism syndrome. Premortem diagnosis by cryostat frozen sections.


At the receiving end--a DOCTOR's personal recollections of cardiac-valve replacement.


Control of anticoagulant treatment.

Control of anticoagulant treatment.


Carcinoma of breast.

Carcinoma of breast.


The treatment of thyroid disease.

The treatment of thyroid disease.


Sudan Black B staining of Cryptococcus neoforman in smears.


Phytanic acid in patients with Refsum's syndrome and response to dietary treatment.


The place of radiotherapy in the management of the squamous cell carcinoma of the supraglottic larynx.


Extradural metastasis in medulloblastoma 10 years after treatment. Report of a case.


The extra-adrenal neuroblastoma:  high radiocurability and diagnostic accuracy.


Percutaneous cordotomy. A simplified approach to the management of intractable pain. Cordotomy for palliation of intractable pain was simplified by the use of a stereotactic percutaneous technique. The procedure is performed at the high cervical level and has been found to give good results for pain in the upper as well as the lower extremity and the trunk. Respiratory complications are the major hazard, but they may be reduced by careful selection and evaluation of patients.


On the electroencephalogram of man. Fourth report.


On the electroencephalogram of man. Sixth report.


On the electroencephalogram of man. Fifth report.


On the electroencephalogram of man. Seventh report.


Hans Berger and the discovery of the electroencephalogram.


On the electroencephalogram of man. Ninth report.


On the electroencephalogram of man. Eighth report.


On the electroencephalogram of man. Tenth report.


On the electroencephalogram of man. Eleventh report.


On the electroencephalogram of man. Twelfth report.


On the electroencephalogram of man. Thirteenth report.


On the electroencephalogram of man.

On the electroencephalogram of man.


On the electroencephalogram of man. Fourteenth report.


On the electroencephalogram of man. Second report.


On the electroencephalogram of man. Third report.


Cellular changes in lymph nodes of the guinea pig during sensitization and elicitation of DNCB contact dermatitis.


Anaphylatoxin tachyphylaxis and anaphylactic histamine release.


Immunofluorescencetudies in penicillin hypersensitivity.


Application of standard micro-anatomical staining methods to epoxy resin-embedded sections. Staining of semi-thin sections of osmium-fixed epoxy resin (Epon or Araldite)-embedded tissues with haematoxylin and acid dyes as counterstains (eosin or phloxin) was successfully achieved after intense oxidation using hydrogen peroxide as the oxygen donor. Results are closely similar to those obtained with paraffin sections (haematoxylin and eosin): nuclei stain blue, cytoplasm and extracellular structures (eg, collagen, elastica, basement membranes) stain with varying shades of red. Preliminary studies show that similarly good results, comparable with standard paraffinembedded histological materials, can be obtained, using H(2)O(2) pretreatment, with Weigert's iron haematoxylin, Mallory's phosphotungstic acid haematoxylin, Alcian blue, PAS reaction, Sudan III, Sudan black, oil red, Gomori's aldehyde fuchsin, and Baker's acid haematein.


Nature of Bowman's layer.

Nature of Bowman's layer.


The artery of the sinuatrial node (Keith-Flack) of the human heart. (Anatomo-roentgenological study).


Metabolic dependence of fast axoplasmic transport in nerve. Fast axoplasmic transport, shown in cat sciatic nerves by a crest of labeled activity after injection of the L7 ganglion with [(3)H]-leucine or [ (3)H]-lysine, was stopped within 15 minutes after death of the animals by bleeding. If the sciatic nerves were removed from the animals and placed in a chamber supplied with oxygen at 38 degrees centigrade, fast transport was sustained. Transport was rapidly blocked in similar in vitro preparations when the nerves were kept in a nitrogen environment. Fast axoplasmic transport is closely dependent upon oxibdative metabolism.


Studies on rat liver ribonucleases. 3. Studies on biological functions of rat liver ribonuclease. ANL-7409.


On the occurrence and histochemistry of granules in the optic nerve of Punctius ticto (Gunther).


Studies in pollen allergy. I. A method for estimating histamine release from sensitised leucocytes in the presence of serum.


Heparin and histaminase release by anaphylatoxin in guinea pigs.


Nonmast-cell histamine kinetics. 3. Uptake, metabolism and decline of H3-histamine in the female rat and effects of endogenous histamine release.


A vibrophonocardiogram cardiac-output computer.


Digitizing records of cardiovascular studiesj--the graph digital reader.


Distribution of protein-bound zinc in normal and cirrhotic serum.


Studies in myoclonus epilepsy (Lafora body form). II. Polyglucosans in the systemic deposits of myoclonus epilepsy and in corpora amylacea.


Operating room nursing in the basic curriculum: an opinion.


Studies on burns. XI. Immunoglobulin and alpha 2 macroglobulin patterns and bacterial flora during treatment of burns with warm dry air.


Electron microscopy of neoplasms in the lung with special emphasis on the alveolar cell carcinoma.


Recurrent respiratory infections in a family with immunoglobulin A deficiency.


Genetic control of immunoglobulin allotypes in the fowl.


Immunoglobulin E in "healed" atopic dermatitis and after treatment with corticosteroids and azathioprine.


Investigations on eosinophilia. The influence of histamine, antigen-antibody complexes containing gamma-1 or gamma-2 globulins, foreign bodies (phagocytosis) and disrupted mast cells.


Methimazol induced aplastic anemia.

Methimazol induced aplastic anemia.


Continuity of fantasy: dreams and dreaming in the arts.


Drug research and the meaning of dreams.


Further studies on the process of histamine release from sensitized guinea-pig bone marrow basophils by antigen.


Studies in pollen allergy. II. Comparison of leucocyte sensitivity and levels of blocking antibody in hay fever subjects administered allpyral or pollaccine.


Studies on the levels of immunoglobulins in normal human urine with particular reference to IgE.


Lanthanum staining of developing chick cartilage and reaggregating cartilage cells.


Gel-electrofocusing in combination with immunodiffusion.


Increased susceptibility to infection associated with abnormalities of complement-mediated functions and of the third component of complement (C3).


Critical periods and cognitive development in the first 2 years.


Transplacental passage and persistence in serum for 6 9/12 years of lophenoxic acid (teridax) in a child.


Cretinism in rats: enduring behavioral deficit induced by tricyanoaminopropene. Rats reared on diets containing tricyanoaminopropene, the antithyroid compound that stimulates RNA synthesis, showed a deficit in performance on automated closed-field maze tests many weeks after discontinuation of the drug. The rats were also tested while still receiving the drug, and performance deficits were indicated in tests of Y-maze reversal and manual closed-field maze performance; rats treated with the drug and with thiouracil behaved in a highly similar fashion on several tasks. No evidence of facilitation by tricyanoaminopropene appeared in any of the eight learning situations used. Exposure to tricyanoaminopropene before and after birth, at doses sufficient to produce anatomical cretinism, apparently induces an enduring behavioral deficit which is similar to that of neonatal thyroidectomy-induced cretinism in rats and which parallels the mental retardation associated with human cretinism.


Airborne lead and carbon monoxide at 45th Street, New York City. Daily business-day traffic determines the diurnal lead concentration as well as diurnal carbon monoxide concentration. Daily averages of 7.5 micrograms per cubic meter for lead and 13 parts per million of carbon monoxide were found for the 10-week period of the study. Correlations were demonstrated for lead and traffic and lead and carbon monoxide.


The presence of nerves in original and regenerated synovial tissue in patients synovectomised for rheumatoid arthritis.


Study on the effect of actinomycins in tissue cultures from human brain tumours.


Immunoglobulin levels during childhood, with special regard to IgE.


Nevus anemicus.

Nevus anemicus.


Effects of diphenylhydantoin on canine atria and A-V conduction system.


Changes resembling lupus erythematosus after prolonged treatment with Ro-4-4602, a potent inhibitor of 5-HTP-carboxyliase, in white rats.


The effect of benzethonium chloride on the antigens of pertussis vaccine.


Immunoglobulins in nasal polyp fluid.

Immunoglobulins in nasal polyp fluid.


Absorption of reagin by human tissues in vitro.


Electron chemistry and collagen structure.


Collaborative analysis of long-term anticoagulant administration after acute myocardial infarction. An international anticoagulant review group.


Coeliac infertility: an indication for dietary gluten restriction?


Children of mothers with phenylketonuria.


Case of self-poisoning with multiple antidepressant drugs.


Prenatal determination of fetal sex and chromosomal complement.


Increased levels of serum-creatine-phosphokinase after transient limb ischaemia in patients with muscular dystrophy.


A genetic relationship between diabetes and cancer.


Distance marker rings on endotracheal tubes.


Long-term anticoagulants after acute myocardial infarction.


Prostaglandins.

Prostaglandins.


A contribution to the aetiopathogenesis and treatment of acute thrombophlebitis.


Approved names.

Approved names.


Intermittent thyroid treatment?

Intermittent thyroid treatment?


Glioma of the optic nerve.

Glioma of the optic nerve.


L-dopa in chronic manganese poisoning.

L-dopa in chronic manganese poisoning.


Antibiotic-resistant Staphylococcus aureus and hospital antibiotic policies.


War prevention and the doctor.

War prevention and the doctor.


Human placental lactogen.

Human placental lactogen.


Inflation in the laboratory.

Inflation in the laboratory.


Delayed hypersensitivity in hay-fever.

Delayed hypersensitivity in hay-fever.


Emergency ward.

Emergency ward.


Group homes for recovered psychiatric patients.


Bacteria in suction machines.

Bacteria in suction machines.


Pseudomonas in ventilators.

Pseudomonas in ventilators.


Case of apparent reinfection with rubella.


Institute of gerontology.

Institute of gerontology.


Detection of bacteriuria.

Detection of bacteriuria.


Drug names.

Drug names.


Tropical high-altitude peripheral oedema.


Isolated trigeminal neuropathy.

Isolated trigeminal neuropathy.


Death penalty.

Death penalty.


Bleeding abdominal-wall varices.

Bleeding abdominal-wall varices.


Renal function after transplantation.

Renal function after transplantation.


Dangers of decimals.

Dangers of decimals.


Artists and photographers.

Artists and photographers.


Coronary disease presenting as cardiomyopathy.


Primary sex-ratio and size of family.

Primary sex-ratio and size of family.


Ampicillin rashes.

Ampicillin rashes.


Vascular factors in acute pancreatitis.

Vascular factors in acute pancreatitis.


Brucellosis.

Brucellosis.


Deficiency.

Deficiency.


Rapid technique for chromosome examination.


Spider bites.

Spider bites.


Haemolytic-uraemic syndrome following mumps vaccination.


Haemolytic-uraemic syndrome and heparin therapy.


Skin-grafting leg ulcers.

Skin-grafting leg ulcers.


Insulin stimulation of cholesterol synthesis by arterial tissue.


Man and his pesticides.

Man and his pesticides.


Seasonal variations of plasma-cortisol in haemophilia-A.


Intrathecal methotrexate.

Intrathecal methotrexate.


Resuscitation ambulances.

Resuscitation ambulances.


Direct male-to-male transmission of the XY Turner phenotype.


Rectal bleeding from gastric tissue in the rectum.


Precipitins to aqueous extracts of flour in coeliac disease.


The changing British drug scene.

The changing British drug scene.


Assessing the sputum.

Assessing the sputum.


Treatment of scopolamine-induced delirium.


Measuring folate absorption.

Measuring folate absorption.


Terence Cawthorne, Kt, Hon. M.D. Uppsala, Hon. LL.D. Syracuse, F.R.C.S.


Robert Wilfred Scarff, C.B.E., M.B. Lond., F.R.C.S., F.R.S.E.


Kenneth Fraser, O.B.E., M.D., Edin., D.P.H., F.R.S.E.


Oral methotrexate therapy of gastrointestinal carcinoma.


Management of tumors of the liver.

Management of tumors of the liver.


Synthesis of new hydrazidines with vasoconstrictor activity.


Anthropological record for congenital developmental defects of the face (especially clefts).


A case of structural chromosomal anomaly in D (13-15) group.


Method of repair of upper lip defects with a wedge-shaped flap taken from the lower lip.


Surgical treatment of deformations of the upper lip and nose after plasty of the lip in adults with unilateral hare lip.


On the problem of favourable age and the most favourable method for palatinal surgery in bilateral total clefts.


Repair after vulvectomy for giant condylomata acuminata.


Possibilities of the reconstruction of the thumb injure-loss-accident.


Some methods of plastic reconstruction of tendons of the finger flexors.


Lesions of finger aponeurosis at the level of the distal interphalangeal joint.


Experiences with the surgical treatment of elephantiasis.


Cytologic studies after insertion of intrauterine contraceptive devices.


The effect of antigen competition on both the primary and secondary immune capacity in mice.


The clonal nature of antibody formation. I. Clones of antibody-forming cells of poly-D-alanine specificity.


Binding properties of anti-dinitrophenylated-bacitracin A antibodies produced in guinea pigs.


Isolation and characterization of IgA produced by an established human lymphocytoid cell line.


Demonstration of viral antibody activity in two immunoglobulin G subclasses in patients with varicella-zoster virus infection.


Pyrrolidonecarboxylic acid at the N-terminal positions of polypeptide chains from leopard shark immunoglobulins.


Intracellular "monoclonal" immunoglobulin in non-secretory human myeloma.


Concanavalin A-induced release of skin-reactive factor from lymphoid cells.


Contribution of the b and c light chain loci to the composition of rabbit gamma G-immunoglobulins.


Radioisotope studies of thyroid function in progressive muscular dystrophy.


Development and duration of mumps fluorescent antibodies in various immunoglobulin fractions of human serum.


Histamine liberation into the cerebrospinal fluid by the drugs applied intraventricularly.


The incidence of residuals of infectious hepatitis.


Identification of enterochromaffin cells in adjacent epon-embedded sections at light and electron microscopic levels.


Purification and binding properties of nurse shark antibody.


Circulating siderocytes in human subjects.


Gel filtration studies of serum B 12 binding: an abnormal pattern in patients with vitamin B 12 deficiency.


Type I hypersensitivity and the skin.

Type I hypersensitivity and the skin.


Generalized cytosiderosis in two cases of progressive myoclonic epilepsy with Lafora inclusion bodies. Histopathological and ultrastructural studies.


Antibodies to Toxocara in the sera of visceral larva migrans patients: the significance of raised levels of IgE.


Immunoconglutinin and complement changes in children with acute nephritis.


Immunoglobulin classes of antibodies produced in the primary and secondary responses in man.


Immunoglobulin synthesis by human peripheral lymphocytes and thymocytes in vitro. Specificity of immunochemical methods and stimulation by phytohaemagglutinin.


Changes in the histochemical nature of neurosecretory materials during axonal transport in the crab Paragrapsus gaimardii.


Nucleolar structure in root-tip cells of Allium cepa.


Distribution of the sulphur-35-labelled goitrogen L-5-vinyl-2-thio-oxazolidone in the rat.


The corticotroph cells of the anterior pituitary gland of a reptile: Cnemidophorus l. lemniscatus (Sauria, Teiidae).


Dual localization of acid hydrolases in endoplasmic reticulum and in lysosomes. I. Beta-glucuronidase staining reactions and cytochemical studies on kidney in androgen-stimulated mice.


Mechanisms of chromation hematoxylin stains.


On the use of eosin as a fluorescent dye to demonstrate mucous cells and other structures in tissue sections.


Use of propranolol in the treatment of angina pectoris and cardiac arrhythmias.


Electrocardiographic changes following blood transfusion.


Occurrence of the Inv genetic markers in the subgroups of human kappa chains.


Studies on bronchial asthma, concerning histamine release reaction.


Current concepts in management of thyroid disease.


New findings regarding autoimmune factors in skin disease.


Modified sequential oral contraception employing mestranol with chlormadinone.


Move away from mediocrity.

Move away from mediocrity.


The operating room nurse and continuing education.


A new nurse becomes a patient-centered nurse practitioner in the operating room.


Look out law suits.

Look out law suits.


Investigation of endemic goitre in Sudan.


Prevention of maternal Rh sensitization: anti-Rh immune globulin.


A modified Holzer technic for staining glial fibers in paraffin sections.


In vitro effects of heterologous antibodies on the metabolism and fine structure of Yoshida ascites hepatoma cells.


IMC dedicated to serving the needs of exceptional children.


Postnatal development of tetraploid DNA content in rat purkinje cells: a quantitative cytochemical study.


Application of dispersion staining to the study of refractive index of dental enamel.


Immunoglobulins of intact epithelium.

Immunoglobulins of intact epithelium.


Acid-reacting stains, softening, and bacterial invasion in human carious dentin.


Shikarpur--West Pakistan.

Shikarpur--West Pakistan.


The future for NATN.

The future for NATN.


Prevention of Rh-haemolytic disease.

Prevention of Rh-haemolytic disease.


Audiovisual techniques in the USA. 1.

Audiovisual techniques in the USA. 1.


Two methods of teaching in the OR.

Two methods of teaching in the OR.


Aseptic nursing technique.

Aseptic nursing technique.


Glaucoma: recent endocrine studies.

Glaucoma: recent endocrine studies.


Angiographic-histologic correlation of eye vessel permeability with protein-bound fluorescent dye.


Histopathology of ischemic optic neuropathy.


Palliative intubation for malignant strictures of the esophagus.


Selection of an optimal procedure for decompression of the obstructed common bile duct. Experimental and clinical observations.


A new mitochondrial myopathy in a patient with salt craving.


Problems in the surgical treatment of pain in malignancies of the head and neck.


Glycogen accumulation following brain trauma.


A new proprietary decalcifying agent: comparison with established methods and use in routine histopathology.


The ultrastructure of metachromatic bodies in cultured fibroblasts in Hunter's syndrome.


Rheumatoid arthritis in the aged.

Rheumatoid arthritis in the aged.


The surgical suite. OR unit manager.

The surgical suite. OR unit manager.


Genetics of the phosphoglucomutase (PGM) system of human red cells. Family-, mother-child- and association-studies.


Segregation and linkage analyses of twelve blood and serum group systems.


Structure of Escherichia coli after freeze-etching. Survival of Escherichia coli, quick-frozen under conditions similar to those employed for freeze-etching, is close to 100%. For determination of cell shrinkage, the diameters of freeze-etched E. coli cells (average, 0.99 mum) were compared with those of preparations after negative staining and after ultrathin sectioning. Negatively stained cells measured from 0.65 to 1.0 mum in diameter, and ultrathin sections showed average cell diameters of 0.70 mum. Freeze-etched replicas of logarithmically growing, as well as stationary, E. coli B cells revealed a smooth, finely pitted cell surface in contrast to cell surfaces seen with other preparative methods. The frozen cell wall may cleave in two planes, exposing (i) a smooth fracture face within the lipid layer and (ii) in rare instances an ill-defined particulate layer. Most frequently, however, cleavage of the envelope occurred between wall and protoplasmic membrane; large areas of the membrane were then exposed and showed a surface studded with predominantly spherical particles, an appearance which did not significantly change when the cells were fixed in formaldehyde and osmium tetroxide before freeze-etching. The distribution of these particles differed between logarithmically growing cells and stationary cells.