Alterations of the cortical oxygen pressure in generalized seizures.


Further results of stimulation experiments in kittens.


Psychological findings in cases with 4-5 c-sec rhythm.


Side to side comparison of acoustic evoked potentials in patients with unilateral intracerebral processes, especially with aphasia.


Fourier analysis of on- and off-effects of evoked potentials.


Human cortical evoked potentials in dichoptic stimulation.


Artefacts in the "silent" EEG.

Artefacts in the "silent" EEG.


The development of sleep spindles during the first 2 years of life.


The value of the EEG recorded with open eyes for differential diagnosis of intracerebral processes: behaviour of physiological and pathological activity.


The reaction of alpha activity during exercise.


Experiments on cholinergic mechanisms for the control of tonic and phasic components of REM sleep.


EEG changes in Jakob-Creutzfeldt's disease under the influence of diazepam.


Demonstration of technical novelties in the field of clinical electroencephalography.


EEG changes with facial injuries.

EEG changes with facial injuries.


A study of axon reflexes in some neurological disorders.


Auditory evoked responses. The basis for a promising objective audiometric test.


The effect of diazepam (Valium) and nitrazepam (Mogadon) on picrotoxin induced seizures in rabbits.


The size of the ventricular system. A comparative study between echoencephalography and pneumoencephalography.


The epileptogenic effect of water-soluble contrast media. A search for less toxic substances.


Mitochondrial RNA from cultured animal cells. II. A comparison of the high molecular weight RNA from mouse and hamster cells. Discrete RNA fractions sedimenting slightly slower than 18s ribosomal RNA have been found in mitochondrial preparations from both hamster (BHK-21) and mouse (L-929) cells. This RNA could be separated into two components, present in approximately equimolar amounts, by prolonged zonal centrifugation or acrylamide gel electrophoresis. The hamster components had sedimentation constants averaging 16.8 and 13.4, and molecular weights (estimated by gel electrophoresis) averaging 0.74 and 0.42 x 10(6) daltons. Mixed labeling experiments showed that the mouse components sedimented and electrophoresed 3-6% more slowly than the corresponding hamster components. The RNA from both cell lines resembled mitochondrial ribosomal RNA from yeast and Neurospora in being GC poor, and in addition the larger and smaller components resembled each other in base composition. These results, taken with those of other recent studies, are compatible with the idea that our high molecular weight mitochondrial RNA is ribosomal; such RNA would then constitute a uniquely small size-class of ribosomal RNA.


Osmium staining of endoplasmic reticulum and mitochondria in the rat adrenal cortex. The zona fasciculata of the rat adrenal cortex synthesizes and secretes glucocorticoids. As observed after aldehyde fixation, the cells in this zone contain an extensive endoplasmic reticulum (ER), a small Golgi apparatus, a moderate number of lipid droplets, and abundant mitochondria with tubulovesicular cristae. Numerous areas within the endoplasmic reticulum and mitochondrial cristae appear clear. In addition, a small percentage of mitochondria encompasses large, clear areas. After immersion of finely minced adrenal cortex in unbuffered 2% OsO(4) (40-48 hr at 40 degrees C), deposits of osmium are seen within the Golgi apparatus, the entirety of the ER, and occasionally within mitochondria. In some mitochondria, the deposits are within cristae; in others, within vacuoles; in still others, in both cristae and vacuoles. These localizations correspond best to the clear areas found in aldehyde-fixed tissue. Osmium is not deposited in lipid droplets, in bar-containing inclusions, in mitochondrial matrix inclusions, or in the peripheral, outer mitochondrial spaces. Addition of zinc-iodide to OsO(4) increases the amount of Golgi apparatus and mitochondrial staining. Adrenocorticotropin (ACTH) does not affect the localization of deposits; hypophysectomy decreases mitochondrial staining. This study (a) emphasizes the necessity for electron microscopic confirmation of osmium localization when this technique is used as a Golgi apparatus stain; and (b) suggests that the ER-staining pattern may be consistent in cells actively synthesizing steroids or steroid-like compounds.


Cytologic specificity of response to Moloney murine sarcoma virus as evident in a transplantable epithelioid neoplasm of the rat.


Transformation and virus production in normal rat thymus cells and those infected with Moloney leukemia virus.


Immunoferritin and immunofluorescent studies with Epstein-Barr virus and herpes simplex virus by use of human sera and hyperimmune rabbit sera.


Characteristics of a new inbred strain of mice (PBA) with a high tumor incidence: preliminary report.


Studies on the antigenic activities of yeasts. V. Effect of alpha-mannosidase digestion on the immunochemical properties of the mannan of Saccharomyces cerevisiae.


Pituitary radiotherapy.

Pituitary radiotherapy.


A theory of self-nonself discrimination. 1) Induction of humoral antibody formation involves the obligatory recognition of two determinants on an antigen, one by the receptor antibody of the antigen-sensitive cell and the other by carrier antibody (associative interaction). 2) Paralysis of antibody formation involves the obligatory recognition of only one determinant by the receptor antibody of the antigen-sensitive cell; that is, a nonimmunogenic molecule (a hapten) can paralyze antigen-sensitive cells. 3) There is competition between paralysis and induction at the level of the antigen-sensitive cell. 4) The mechanisms of low- and high-zone paralysis, and maintenance of the unresponsive state, are identical. 5) High-zone paralysis occurs when both the carrier antibody and the receptor antibody are saturated, so that associated interactions cannot take place. 6) The mechanisms of paralysis and induction for the carrier-antigen-sensitive cell are identical to those for the humoral-antigen-sensitive cell. 7) The formation of carrier-antigen-sensitive cells is thymus-dependent, whereas humoral-antigen-sensitive cells are derived from bone marrow. Since carrier antibody is required for induction, all antigens are thymus-dependent. 8) The interaction of antigen with the receptor antibody on an antigen-sensitive cell results in a conformational change in an invariant region of the receptor and consequently paralyzes the cell. As the receptor is probably identical to the induced antibody, all antibody molecules are expected to be able to undergo a conformational change on binding a hapten. The obligatory associated recognition by way of carrier antibody (inductive signal) involves a conformational change in the carrier antibody, leading to a second signal to the antigen-sensitive cell. 9) The foregoing requirements provide an explanation for self-nonself discrimination. Tolerance to self-antigens involves a specific deletion in the activity of both the humoral- and the carrier-antigen-sensitive cells.


Neoplasia of the solitary kidney.

Neoplasia of the solitary kidney.


The antibody deficiency syndrome--clinical considerations.


The place of cryoprostatectomy.

The place of cryoprostatectomy.


The newer anti-allergic agents.

The newer anti-allergic agents.


The distribution of characters considered to be microforms of cleft lip and-or palate in a population of normal 18-21 year old subjects.


An attempt to treat children with Pierre Robin syndrome orthopaedically.


Surgical treatment of palmar and plantar keratosis.


Pseudohermaphroditism.

Pseudohermaphroditism.


Hypospadias and a new method of its surgical treatment.


One-stage operation for hypospadias.

One-stage operation for hypospadias.


Contribution to the re-hydration of freeze-dried grafts. I. Re-hydration of rib bone grafts (short report).


The revascularization of a free skin autograft.


Experiment with many-layered skin grafts.


The surgical treatment of skin damaged by radiation.


The viability of cartilage transplants.

The viability of cartilage transplants.


A histochemical study on the histogenesis of the mixed tumours of the human salivary glands.


Phage-like particles from a lysogenic Thermomonospora.


The action of visible radiation on the formation and properties of Saccharomyces ascospores.


Enhancing effect of DEAE-Dextran on inclusion counts of an ovine Chlamydia (Bedsonia) in cell culture.


Starch-iodide as a stain for peroxidases.


Combined treatment of parkinsonism with L-dopa and amantadine.


Electron microscopical and immunological observations on the serum-hepatitis (S.H.) antigen in primary biliary cirrhosis.


Autologous transfusions in uraemic patients.


"Free" iron loss in atrophic gastritis, post-gastrectomy states, and adult coeliac disease.


Urinary steroid-excretion patterns after acute myocardial infarction.


Long-term hepatic support by intermittent multi-species liver perfusions.


Detection of thrombosis with iodine-125 fibrinogen. Data reassessed.


Control of tuberculosis.

Control of tuberculosis.


Liver disease in ulcerative colitis.

Liver disease in ulcerative colitis.


Direction for social science.

Direction for social science.


Screening for breast and gynaecological lesions.


Cholera on the Caspian.

Cholera on the Caspian.


Design of skin flaps.

Design of skin flaps.


Septic thrombophlebitis and venous cannulas.


Screening for breast cancer.

Screening for breast cancer.


Child care in Czechoslovakia.

Child care in Czechoslovakia.


Abortion analysis.

Abortion analysis.


"Central" venous pressure.

"Central" venous pressure.


Carrageenan and the human gut.

Carrageenan and the human gut.


Carrageenan: effects in animals.

Carrageenan: effects in animals.


Medical care in the United States.

Medical care in the United States.


Sterilisation.

Sterilisation.


Burkitt lymphoma and malaria.

Burkitt lymphoma and malaria.


Hepatitis-Associated antigen.

Hepatitis-Associated antigen.


Streptokinase for pulmonary embolism.

Streptokinase for pulmonary embolism.


Intracranial venous thrombosis complicating oral contraception.


Prevention of venous thrombosis.

Prevention of venous thrombosis.


Animal sources of Escherichia coli in food.


Spoons and dip-slides.

Spoons and dip-slides.


Swallowed neonatal endotracheal tube.

Swallowed neonatal endotracheal tube.


Plasma-catecholamine estimations.

Plasma-catecholamine estimations.


Glucagon and the heart.

Glucagon and the heart.


Coxsackie myocarditis of the newborn.

Coxsackie myocarditis of the newborn.


Comparsion of antihypertensive agents.

Comparsion of antihypertensive agents.


Dialysis circuit monitors.

Dialysis circuit monitors.


Carbenicillin in renal failure.

Carbenicillin in renal failure.


Serum-enzymes in dialysis patients.

Serum-enzymes in dialysis patients.


48-hour kidney storage.

48-hour kidney storage.


Sputum viscosity in cystic fibrosis.

Sputum viscosity in cystic fibrosis.


Etiology of Crohn's disease.

Etiology of Crohn's disease.


Diabetes, diabetic angiopathy, and growth hormone.


Atypical reactions to bromsulphthalein (B.S.P.).


Stereostethoscope.

Stereostethoscope.


Bedside diagnosis of the myasthenic syndrome.


Birth control and sex ratio.

Birth control and sex ratio.


Anticonvulsant drugs and chromosomes.

Anticonvulsant drugs and chromosomes.


Cytostatic drugs and inflammation.

Cytostatic drugs and inflammation.


James Harkness Margerison, M.B. St. And.


John Marshall, M.C., T.D., M.B. Glasg., F.R.C.P.G., D.O.M.S.


Some considerations dealing with the role of the graft in the pathology of clinical transplantation.


Genetical aspects in experimental induction of the cleft palate by cortisone in inbred strains of mice. A study of the segregation of the cleft palate and some of the genetically conditioned markers.


Epidemiologic studies on congenital malformations. Critical review and new conceptions.


Contribution to the etiopathology of the cleft lip and palate.


Application of tube pedicle flap for covering defects of the conjunctival sac.


Classification of scarred neck contractures and their surgical therapy by methods of local plastic operation.


Treatment of hypospadias.

Treatment of hypospadias.


Proteinaceous cysts of the ciliary epithelium. II. Their occurrence in nonmyelomatous hypergammaglobulinemic conditions.


Dendritic fields of the retinal ganglion cells in the cat.


Continued studies on the axonal transport of nerve proteins to muscle.


The effect of hydrocortisone on immunoglobulin metabolism. The serum concentration of all subclasses of IgG (gamma(2)A, gamma(2)B, and gamma(1)) as well as IgA and IgM were reduced in normal and low pathogen mice receiving hydrocortisone acetate. Turnover studies using (131)I-labeled gamma(2)A subclass of IgG demonstrated that high dose corticosteroids cause a significantly shortened survival (increased catabolic rate) which contributes to the observed hypogammaglobulinemia. This increase in fractional catabolism is not due to excess loss in the urine or stool but reflects an increase in endogenous catabolism.


Dihydrotestosterone in prostatic hypertrophy. I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man. To explore the relation between androgens and prostatic hypertrophy in man, the concentrations of testosterone, dihydrotestosterone, and androstenedione and the rate of conversion of testosterone to dihydrotestosterone have been measured in normal and hypertrophic prostate tissue. First, a double isotope derivative technique was adapted for the measurement of tissue androgen content in 15 normal and 10 hypertrophic prostates. Although there was no significant difference in the content of androstenedione and testosterone between the two types of tissue, the content of dihydrotestosterone was significantly greater in the hypertrophic tissue (0.60 +/-0.10 mug/100 g) than in the normal glands (0.13 +/-0.05 mug/100 g). Second, a regional study was performed in three normal prostates and four glands with early hypertrophy, and it was demonstrated that the dihydrotestosterone content was two and three fold greater in the periurethral area where prostatic hypertrophy usually commences than in the outer regions of the gland. Finally, the rate of conversion of testosterone to dihydrotestosterone has been measured under standardized conditions in tissue slices from 4 normal and 20 hypertrophic prostates. There was no significant difference in the rate of dihydrotestosterone formation between the two types of gland (6.0 +/-0.8 and 7.8 +/-0.5 mumumoles/15 mg of tissue per hr). While the mechanism by which dihydrotestosterone accumulation occurs remains unexplained, it is possible that the local accumulation of dihydrotestosterone may be involved in the pathogenesis of prostatic hypertrophy in man.


Dihydrotestosterone in prostatic hypertrophy. II. The formation and content of dihydrotestosterone in the hypertrophic canine prostate and the effect of dihydrotestosterone on prostate growth in the dog. Three types of studies have been performed in immature, mature, and hypertrophic prostate glands of the dog. First, the concentrations of testosterone and dihydrotestosterone have been measured in the three types of gland. Dihydrotestosterone was the predominant hormone recovered in all prostates studied and was present in approximately five times higher concentration in the hypertrophic as compared to the other types of dog prostate. Second, pharmacological doses of dihydrotestosterone were administered to castrated dogs for 9 months and resulted in a distinct acceleration of prostatic growth as compared to testosterone treatment. Third, the rates of formation and degradation of dihydrotestosterone were measured in normal and hypertrophic tissue and were found to be essentially the same. These observations suggest that dihydrotestosterone accumulation may be causally linked to the development of canine prostatic hypertrophy. However, the mechanism by which dihydrotestosterone accumulates in the prostate remains to be determined.


Immunoglobulin allotypic determinants on rabbit lymphocytes.


Promising trends in neuroscience.

Promising trends in neuroscience.


Electromechanical correlations in the mammalian heart muscle.


Behaviour of mast cells in the skin of mice treated with benzpyrene.


Biological variables associated with mothers of children affected with the G1-trisomy syndrome. (Down's syndrome).


Multiplication of fowlpox virus in chicken embryo fibroblastic cell cultures.


Cross-reactions between human and animal plasma proteins. II. The influence of structural and functional factors.


Observations on the immune globulin levels of neonatal calves and their relationship to disease.


Effects of Escherichia coli on germ-free and gnotobiotic pigs. II. Serum proteins and antibodies.


Hyaline arteriolosclerosis in wild animals.


Effect of histomoniasis on the serum proteins of the fowl.


Microprobe analysis of Protargol stain deposition in two protozoa.


Elongated structures present in cells infected with influenza viruses.


A research standard for human serum immunoglobulins IgG, IgA and IgM. A pooled human serum, partly diluted, has been distributed into ampoules and freeze-dried in several batches. The freeze-dried material has been examined in an international collaborative assay and certain properties have also been estimated in individual laboratories.On the basis of these tests this material was considered to be suitable for use as a standard for the estimation of IgG, IgA and IgM for clinical purposes using the single-radial-diffusion or similar techniques. Greater uniformity of results than is obtained at present should be achieved if this material were in general use.Estimates of immunoglobulins from different laboratories using this material as a standard showed small but significant variability. This variability was probably related to the heterogeneity of immunoglobulins and of antisera, and it limits the precision of immunoglobulin estimations by techniques at present in use.Batches of this material have been distributed to various centres. 67/68 has been established as the British research standard for human serum immunoglobulins IgG, IgA and IgM for which the unit of potency is defined as the activity present in 0.8147 mg of dry powder. The average activity per ampoule of 67/86 is 100 units of IgG, IgA and IgM. The average activities of other related preparations have been estimated.


Lack of seasonal variation in protein-bound iodine.


Iodine metabolism in autoimmune thyroiditis.


Indications for prostatectomy.

Indications for prostatectomy.


Studies on cytophilic antibodies. A mouse serum "antibody" having an affinity for macrophages and fast alpha-globulin mobility.


Chemical linkage of polycyclic hydrocarbons to deoxyribonucleic acids and polynucleotides in aqueous solution and in a buffer-ethanol solvent system.


Characteristics of antigenic determinants of intact cell surfaces.


Volume changes accompanying the antibody-antigen reaction.


Ultraviolet absorbing dyes as histochemical reagents.


Juvenile rheumatoid arthritis--a serologic survey of 200 consecutive patients.


Spontaneous renal carcinoma in a New Zealand white rabbit.


Appearance and distribution of ectromelia virus inclusion bodies in experimentally infected mice.


Two ways to protein.

Two ways to protein.


Measles.

Measles.


Familial metaphyseal dysplasia.

Familial metaphyseal dysplasia.


Blood-groups and nasopharyngeal carcinoma.


Prevention of venous thrombosis.

Prevention of venous thrombosis.


Drastic cures for obesity.

Drastic cures for obesity.


Side-effects of insulin contaminating commercial glucagon.


Smoking, air pollution, bronchitis, and population mobility.


Hydroxylysinuria.

Hydroxylysinuria.


Cryotherapy in head and neck cancer.

Cryotherapy in head and neck cancer.


Early diagnosis of lung cancer by cytology.


Electrophoresis and immunodiffusion techniques on cellulose acetate membrane.


Some morphological features of bluetongue virus.


Diagnosis of hyperthyroidism. Statistical evaluation of laboratory and clinical criteria.


Simple method for quantitive densitometry of polyacrylamide gels using fast green.


The genetically determined binding of alcian blue by a minor fraction of yeast cell walls.


The dissociation in vitro of the alpha- and beta-lipoprotein components of human and rat very low density lipoproteins.


The wheezing patient. Problems in the differential diagnosis of allergic bronchial asthma.


Selecting content in medical-surgical nursing for the associate degree nursing program.


Selective gamma-g globulin deficiencies in patients with recurrent pyogenic infections.


Synthesis of immunoglobulin heavy and light chains by the free ribosomes of a mouse plasma cell tumor. Free and membrane-bound ribosomes have been isolated from a mouse plasma cell tumor secreting immunoglobulins, and allowed to synthesize proteins under cell-free conditions. Analysis of the products of synthesis by autoradiography of immunoelectrophoresis and peptide maps indicates that both types of ribosomes synthesize heavy and light immunoglobulin chains.


Thyroidal iodine and proteins in autoimmune thyroiditis.


Implications of heavy chain disease protein sequences for multiple gene theories of immunoglobulin synthesis. The sequence of the amino-terminal 34 amino acids of gamma-heavy chain disease (gamma-HCD) protein Hi is homologous with the amino-terminal region of immunoglobulin heavy chains. gamma-heavy chain disease is smaller than a normal gamma-chain, but has the carboxy-terminal composition expected for gamma-chains and must, therefore, contain an internal deletion. Comparison of the Hi sequence with that of gamma-heavy chain disease Zu, which also has an internal deletion, indicates that the site of internal deletion is not a constant characteristic of gamma-heavy chain disease proteins. Heavy chains can be assigned to subgroups on the basis of variable region sequences. The variable regions of Hi and one other protein differ significantly from those determined for other heavy chains, and these two proteins are assigned to a new heavy chain variable region subgroup, V(HIV). It has been suggested that single immunoglobulin heavy chains are the products of two separate structural genes and that variable region genetic information is translocated and integrated into common region information. These multiple gene theories make no prediction as to whether DNA or RNA is translocated. gamma-heavy chain disease proteins provide unique information that indicates that if translocation is required for the production of immunoglobulin heavy chains, it is DNA, not RNA, that is translocated.


The serum proteins identified by means of the Laurell crossed electrophoresis.


Metabolism of bence jones proteins in non-myeloma patients with normal renal function.


Electron microscope studies of sperm incorporation into the golden hamster egg.


Immunoglobulin E-mediated respiratory responses of subhuman primates. Reproducibility and effect of certain pharmacologic agents.


Pulmonary responses to inhaled particles. Role of vasoactive substances.


Evaluation of laboratory methods for detecting acute TRIC agent infection.


Metabolic activities of thyroid glands from tapazole treated rats.


Evaluation of the triiodothyronine suppression test in the treatment of Graves' disease.


A whole-mount cholinesterase technique for demonstrating corneal nerves: observations in the albino rabbit.


Further experimental studies of dynamic propositions in psychoanalysis. On the function and meaning of regressive thinking.


The development of the child's sense of his sexual identity.


The extent of ischemic damage in the myocardium of the cat after permanent and temporary coronary occlusion.


Effect of water pressure irrigation on stainable material on the teeth.


Palliative esophagogastrostomy for inoperable carcinoma of the esophagogastric junction.


Plasma protein changes in mild thermal trauma.


Pick's disease with compound intraneuronal inclusion bodies.


Benign fibro-osseous lesions of the mandible and maxilla. A review of 35 cases.


Mesonephroma ovarii (hypernephroid carcinoma). Light microscopic and ultrastructural study of a case.


Adult-type Gaucher's disease: a secondary disorder of iron metabolism.


A study of the late form (type Lundborg) of progressive myoclonic epilepsy.


Discharge of the terminally-ill patient.


Astrocytes in formalin-fixed paraffin sections. A new modification of Cajal's technic and comparison with the hematoxylin and eosin method.


Guinea pig ovary and testis: demonstration of common gonad specific antigens in the ovary and testis.


Myocardial necrosis induced by isoproterenol in rats. Changes in serum protein, lipoprotein, lipids and glucose during active necrosis and repair in arteriosclerotic and nonarteriosclerotic animals.


The judgment of vowel quality.

The judgment of vowel quality.


Localization of Treponema pallidum immobilizing antibody in human immunoglobulins.


The management of terminal carcinoma with oral potassium permanganate. Oral potassium permanganate has been used in the management of terminal carcinoma in three patients. Symptomatic improvement occurred in all three, with elimination of oral foetor in one patient and diminished requirement of analgesics in the other two. The mental state of each patient was improved and normal activities were resumed.


Excretion of immunoglobulins in Burkitt's lymphoma. IgM was detected in the urines of 4 out of 17 patients with Burkitt's lymphoma. This IgM emerged from Sephadex G 200 column in two different peaks strongly suggesting sub-units of the intact molecule. IgM was not detected in any of the control urines. The total protein excreted in the urine of Burkitt's lymphoma patients is higher than in controls and may be due to renal involvement. Intact IgA and IgG as well as fragments of IgG were present in the urines of all Burkitt patients as well as in controls. Six of 16 Burkitt's lymphoma patients had reduced serum levels of IgG. Four of these also had reduced serum IgM. The low mean concentration of serum IgM confirms our previous studies.


The effect of tumour growth on immune competence. A study of DMBA mammary carcinogenesis in the rat. Circulating antibody response to flagella antigen has been measured in three groups of Sprague-Dawley rats after feeding with 7.12.DMBA in an attempt to differentiate carcinogen and tumour growth as causative agents in the depression of immune response seen in these animals. DMBA fed female rats developing tumours had progressive depression of both primary and secondary response as compared to control animals, and 7S and 19S antibody fractions were equally affected. Removal of tumours did not result in recovery of response. Attempts to prevent tumour development by mammectomy after DMBA feeding were unsuccessful, but the similar number of tumours found in this group was associated with an equal degree of antibody depression to that seen in the first experiment. Male animals fed DMBA did not develop malignant tumours, and showed no depression of immune response. Results suggest that tumour development plays a part in the depression of circulating antibody response seen in these animals, but that it is not directly related to the number of tumours, and is not reversible by tumour excision.


A staining technique to demonstrate erythrocyte refractile bodies in cat blood.


The effect of haemoglobin on the detection of immunoglobulins in calf sera.


Preparation and purification of horse antihuman lymphocyte globulin (ALG).


Palliative treatment of dysphagia in advanced carcinoma of stomach.


Cardiac transplantation in man. 8. Survival and function.


Controlled trial of cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood.


Ovulation stimulation. Problems of prediction of response to gonadotrophins.


Coronary prognostic index for predicting survival after recovery from acute myocardial infarction.


Hypercholesterolaemia in borderline hypothyroidism. Stage of premyxoedema.


Iron therapy in patients on maintenance haemodialysis.


Further observations on Kveim test in Crohn's disease.


Hyperaluminaemia from aluminum resins in renal failure.


Subacute sclerosing panencephalitis: a zoonosis following aberrant measles.


Further assessment of the venous-compression test in hyperparathyroidism.


Immunosuppression in nephritis.

Immunosuppression in nephritis.


Semiautomatic electrocardiographic monitoring.


Laryngeal strombomicroscope.

Laryngeal strombomicroscope.


Pneumatic intermittent-compression legging simulating calf-muscle pump.


Treatment of infertility.

Treatment of infertility.


Epidemiology of gallstone disease.

Epidemiology of gallstone disease.


Children in isolation units.

Children in isolation units.


Hopeful regulations.

Hopeful regulations.


Injuries to knee ligaments and hypermobility.


Initiation of protein synthesis.

Initiation of protein synthesis.


Housewives' hands.

Housewives' hands.


Drift from science.

Drift from science.


Revolution in community welfare.

Revolution in community welfare.


A group home project.

A group home project.


Medical care in the United States.

Medical care in the United States.


Intermittent complete heart-block.

Intermittent complete heart-block.


"Renpenning" syndrome.

"Renpenning" syndrome.


Effect of anticonvulsant drugs on insecticide residues.


Phenobarbitone in posthepatitic unconjugated hyperbilirubinaemia.


Portable heparin injector.

Portable heparin injector.


Beta-hydroxyisovaleric aciduria and beta-methylcrotonylglycinuria: a new inborn error of metabolism.


Screening for phenylketonuria.

Screening for phenylketonuria.


An unusual case of rabies.

An unusual case of rabies.


Immunoglobulins in schizophrenic patients.


Lithium distribution in the brains of two manic patients.


Congenital chromosome abnormalities and leukaemia.


Great corn mystery.

Great corn mystery.


The E.E.G. in herpes-simplex encephalitis.


Treatment of primary polycythaemia.

Treatment of primary polycythaemia.


Early effect of humanae vitae?

Early effect of humanae vitae?


Studies from the hair.

Studies from the hair.


Smoking and frusemide diuresis.

Smoking and frusemide diuresis.


Tetanus: new treatment and prophylaxis.

Tetanus: new treatment and prophylaxis.


Corticotrophin-induced growth-hormone release.


Is lyonisation total in man?

Is lyonisation total in man?


Multiply resistant staphylococci.

Multiply resistant staphylococci.


Accelerated nucleic-acid synthesis in uraemic lymphocytes.


Transformation of xerodermapigmentosum cells by SV40.


G.M.C. retention fee.

G.M.C. retention fee.


Hypocholesterolaemia in anaemia.

Hypocholesterolaemia in anaemia.


The diagnosis and treatment of children with learning and developmental problems. A community service for medical group practice.


Albumin metabolism and gastrointestinal protein loss in children with nephrotic syndrome.


Atypical changes in thyroid follicular cells secondary to radioiodine.


Experimental atherosclerosis in normal and subdiabetic rabbits. I. Short-term studies.


Angiotoxic activity of 4'fluoro-10-methyl-1,2-benzanthracene in the rat.


Lysosomal site of crystalline deposits in cystinosis as shown by ferritin uptake.


Spectrum of aging changes in temporal arteries. Its significance, in interpretation of biopsy of temporal artery.


Naturally occurring human antibodies to pepsin-digested IgA.


Benign prostatic hypertrophy and uraemia. A review of 315 cases.


Recurrence of hyperthyroidism shortly after return of normal suppressibility by triiodothyronine.


Argyrophilic cells of the dog pancreas following different silver stains.


Detection and characterization of DNA in mixed (IgG-IgM) cryoglobulins.


The measurement of serum immunoglobulin E levels in healthy adults and children and in children with allergic asthma.


A study on the detection of human reagins with rat peritoneal mast cells.


Serum lipoproteins of rats bearing transplanted Morris hepatoma 7777.


The immune responses and lymphoid tissues of neonatally thymectomized, X-irradiated mice.


Hematologic findings in certain small cetaceans.


Naturally occurring cutaneous streptothricosis in a white-tailed deer (Odocoileus virginianus).


Type A enterotoxemia in captive wild goats.


The disposition of proteinpolysaccharide in the epiphysial plate cartilage of the young rabbit.


Subacute sclerosing panencephalitis-like syndrome in the adult baboon (Papio sp.).


A multiple-choice audio-visual discrimination apparatus with quick interchange display and response panels.


Medullary tractotomy. A surgical procedure providing relief from severe pain due to cancer of head and neck.


A comparative study of blood fibrinolytic activity in normal women, pregnant women and women on oral contraceptives.


Gastric cytology.

Gastric cytology.


Assessing immunization procedures.

Assessing immunization procedures.


Endocrine profile of a new progestational steroid. 4,6-dichloro-17 alpha-hydroxy-pregna-4,6-diene-3,20-dione, acetate (Ro 7-2133).


Successes and failures in the search for antibiotics.


Recent progress in pharmacogenetics.

Recent progress in pharmacogenetics.


In vivo histamine levels with hypoxia and compound 48-80.


Demonstration of the fenesrated membrane (membrana fenestrata) in the human arterial wall by stained tissue segment.


Rapid method for separation of blood cells.


The basis of differential staining of ascospores and vegetative cells of yeasts.


Studies on the immunogenicity of antigen-antibody precipitates. II. The suppressive effect of anti-carrier and anti-hapten antibodies on the immunogenicity of dinitrophenylated human gamma G globulin.


Cytochemical detection of cytochrome oxidase activity in bacteria.


Morphology and entry of enveloped and deenveloped equine abortion (herpes) virus. Selective removal of the envelope of equine abortion (herpes) virus was accomplished by utilizing the nonionic detergent Nonidet P-40 followed by sonic treatment. The deenveloped particles differ significantly in size and buoyant density from the enveloped form. The cellular entry of purified enveloped and purified deenveloped virus was examined by electron microscopy during critical time periods. Both forms appeared to enter cells by a viropexis mechanism in which particles were engulfed by pseudopodia which either surround the virus and fuse with the cell membrane or to other pseudopodia, forming fusion vacuoles containing from one to numerous viral particles. This mode of entry was noted extensively at 5 min postinoculation. Deenveloped particles were apparently infectious only for hamsters, with a large inoculum being required. Contamination by enveloped forms was not noted after exhaustive search by electron microscopy.


Physical and biological properties of dengue-2 virus and associated antigens. Dengue virus suspensions from mouse brain and cell culture were fractionated into three components by rate zonal centrifugation in sucrose gradients. Infectious virus sedimented in a single zone and possessed hemagglutinating (HA) and complement fixing (CF) activity. Electron micrographs showed the virion to be a spherical particle 48 to 50 nm in diameter with 7-nm spherical structures on its surface. Buoyant density in CsCl of virions from mouse brain was estimated at 1.22 g/cm(3) and from cell culture at 1.24 g/cm(3). During centrifugation of virions in CsCl, an additional HA component appeared with a buoyant density of 1.18 g/cm(3). It was shown in electron micrographs to consist of virion fragments. A noninfectious component with HA and CF activity sedimented in sucrose more slowly than intact virus, had a buoyant density of 1.23 g/cm(3) in CsCl, and appeared as "doughnut" forms measuring 13.8 to 14 nm in diameter. A third component, with CF activity and no HA activity, sedimented very little in sucrose gradients. Particles of the same size and shape as the spherical subunits on the surface of the virion were observed in electron micrographs.


Treatment of Gilbert's syndrome with phenobarbitone.


Cancer prevention.

Cancer prevention.


Excess male false-positives among infants with phenylketonuria.


Parathyroid hormone and experimental osteosclerosis.


ABC of endocrinology. VI. The thyroid gland.


Availability of candidates for consultant posts in chemical pathology.


Prevention of leucocyte-antibody formation.


Reed-Sternberg-like cells in lymphocytic lymphoma and chronic lymphocytic leukaemia.


Cataract surgery and intraocular implants.


Heterotopic ciliated epithelium--müllerian origin?


Effect of corticotropin on plasma-growth-hormone.


Growth hormone in acute myocardial infarction.


Cytogenic analysis of cord-blood lymphocytes.


Relationship of diabetic retinopathy to blood-sugar.


The electrocardiogram in males with the 47,XYY karyotype.


Orange soles.

Orange soles.


Myalgia and bird-keeping.

Myalgia and bird-keeping.


House-dust, mites, and asthma.

House-dust, mites, and asthma.


Repair of the perineum.

Repair of the perineum.


Frederick Cecil Wray Capps, F.R.C.S.

Frederick Cecil Wray Capps, F.R.C.S.


Kidney function after transplantation.

Kidney function after transplantation.


Opening of the cardia.

Opening of the cardia.


Remarks on the nomenclature of cardiac arrhythmias.


The electrocardiogram in complicated acute myocardial infarction.


Primary and secondary male characteristics: the hairiness and large penis stereotypes.


Whipple's disease: newer concepts of therapy.


Pulmonary hyaline membranes in adults receiving oxygen therapy.


Morphology of transmissible gastroenteritis virus of pigs. A possible member of coronaviruses. Brief report.


Characteristics of transducing group A streptococcal bacteriophages A 5 and A 25.


Comparative immunofluorescent studies on measles, canine distemper, and rinderpest viruses. Immunofluorescence of measles, distemper, and rinderpest viruses.


Ultrastructural organization of spheroplasts induced in Mycobacterium sp. smegmatis by lysozyme or glycine.


Compensatory hormonogenic hyperactivity of thyroid homo- and autografts, as well as of regenerates in situ, in the thyroidectomized guinea pig--comparative chemical and radiobiological study.


Effects of adhesive drapes on contamination of operation wounds.


The fist as an external cardiac pacemaker.


Intracranial-pressure changes following head injury.


Comparison of fenfluramine and metformin in treatment of obesity.


Discriminant function based on steroid abnormalities in patients with lung cancer.


Sleep-walking in twins.

Sleep-walking in twins.


Treatment of chronic hepatic encephalopathy.


Dystrophia myotonica: identification of heterozygotes.


A new line on age pigment?

A new line on age pigment?


Selection of housemen.

Selection of housemen.


Finding the typhoid carrier.

Finding the typhoid carrier.


A living wage.

A living wage.


Reserpine in Raynaud's phenomenon.

Reserpine in Raynaud's phenomenon.


One year's experience in a drug-dependence clinic.


Continuity of clinical training.

Continuity of clinical training.


Appointment of provisionally registered house-officers by computer match.


Population policy.

Population policy.


Immunological approach to ageing.

Immunological approach to ageing.


Sterilisation of women.

Sterilisation of women.


Ketamine.

Ketamine.


Variants of alpha-fetoprotein.

Variants of alpha-fetoprotein.


Medical care in the United States.

Medical care in the United States.


Absence of alpha-1-fetoprotein antigen or antibody in maternal sera.


Alpha 1-fetoprotein in Spain.

Alpha 1-fetoprotein in Spain.


Screening blood donors for Au antigen.

Screening blood donors for Au antigen.


Australia antigen and hepatitis.

Australia antigen and hepatitis.


Phenobarbitone in intrahepatic biliary atresia.


Free-radical damage in retrolental fibroplasia.


Battered babies.

Battered babies.


Headache and the eye.

Headache and the eye.


Psychogeriatric assessment unit.

Psychogeriatric assessment unit.


L.A.T.S. and Graves' disease.

L.A.T.S. and Graves' disease.


Blood activity of 125-I-fibrinogen in venous thrombosis.


Catecholamine metabolisn in sympathetic-tumour cells.


L-dopa in progressive supranuclear palsy.


Effects of withdrawing dopa in Parkinson's disease.


An epidemic of dysentery in Nicaragua.

An epidemic of dysentery in Nicaragua.


Role of artificial lighting in decreasing the age of menarche.


Growth hormone and diabetic angiopathy.

Growth hormone and diabetic angiopathy.


Dialysis circuit monitors.

Dialysis circuit monitors.


Death attributed to kidney failure in communities with endemic urinary schistosomiasis.


Systemic nocardiosis treated with trimethoprim and sulphamethoxazole.


Detection of bacteriuria.

Detection of bacteriuria.


Mycoplasma and the urogenital tract.

Mycoplasma and the urogenital tract.


Junior hospital staff in training.

Junior hospital staff in training.


Against vagotomy.

Against vagotomy.


Direction for health service research.

Direction for health service research.


Familial metaphyseal dysplasia?

Familial metaphyseal dysplasia?


Digestion in the newborn.

Digestion in the newborn.


ABO blood groups and Huntington's choera.


Molar absorbance coefficient of rhodopsin.


Clinical value of liver function appraisal by means of 131-I-rose bengal. II. Comparison of the results of 131-I-rose bengal test with other biochemical tests.


Biochemical abnormalities associated with turkey syndrome '65.


Studies on the thyroid activity in the mouse. 2. The effects of stress and other changes in corticotrophin secretion.


Immunologic and electron microscopic studies in Goodpasture's syndrome.


Development and organization of periodontal membrane and physiologic tooth movement.


Interaction of antibiotics with deoxyribonucleic acid. I. Sensitivity of the complexes to nucleolytic enzymes.


The spoken word: delivering a lecture, reading a paper, and giving a demonstration at congresses and meetings.


A unopette for eosinophil counts.

A unopette for eosinophil counts.


A staining technic for differentiating yeast cells from squamous epithelial nuclei on clinical smears.


Iodine and thyroxine metabolism in anephric patients receiving chronic peritoneal dialysis.


Specific demonstration of the human hypophyseal cells which produce adrenocorticotropic hormone.


Thyroglobulin and thyroid acid protease activity in thyroid disease.


Thyroid function in euthyroid Jamaicans.


Studies on tryptophan metabolism in male subjects treated with female sex hormones.


9alpha-halogenated progestagens in the maintenance of pregnancy.


Response to synthetic thyrotropin-releasing hormone in man.


The effect of dose level of intravaginal progestagen on sperm transport, fertilization and lambing in the cyclic Merino ewe.


Severe myositis during recovery from influenza.


An electron-microscope study of bacteria in two cases of Whipple's disease.


Effect of age on calcium absorption.

Effect of age on calcium absorption.


Failure of corticosteroid therapy to correct the hypercalcaemia of malignant disease.


Presentation of cadaveric kidneys for transplantation.


Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin.


Serum-insulin or plasma-insulin?

Serum-insulin or plasma-insulin?


Gastric secretion in a healthy man, 1949-69.


Immunological studies with papain and mexicain. II.


Rapid correction of acidosis and dehydration of cholera with oral electrolyte and glucose solution.


A waste-trap-sterilising method.

A waste-trap-sterilising method.


How many people?

How many people?


Recurrent bacteriuria.

Recurrent bacteriuria.


At what temperature should you keep a baby?


Adding drugs to intravenous infusions.

Adding drugs to intravenous infusions.


Left ventricular hypertrophy and ischaemic heart-disease.


Biological age of man.

Biological age of man.


Corticosteroids and corticotrophins.

Corticosteroids and corticotrophins.


Prospects for social work in general practice.


Contamination of meat carcasses by antibiotic-resistant coliform bacteria.


What about the colleges?

What about the colleges?


Combined treatment of parkinsonism with L-dopa and amantadine.


Registrar General's supplement on abortion.


Battered babies.

Battered babies.


Tests for syphilis in children for adoption.


Ageing.

Ageing.


Animal sources of Escherichia coli in food.


Treatment of chronic moniliasis with lymphocyte transfusions.


Ketamine and polyneuropathy.

Ketamine and polyneuropathy.


Precordial thumping.

Precordial thumping.


Gastrin secretion in the pancreas?

Gastrin secretion in the pancreas?


Red-cell triosephosphate isomerase and chromosome 5.


Diabetes and migraine.

Diabetes and migraine.


Painful deep-vein syndrome.

Painful deep-vein syndrome.


Hyperparathyroidism in chronic renal failure.


Role of artificial lighting in decreasing the age of menarche.


Aetiology of Crohn's disease.

Aetiology of Crohn's disease.


B.C.G. treatment in Crohn's disease.

B.C.G. treatment in Crohn's disease.


Control of tuberculosis.

Control of tuberculosis.


Syndrome of the sea-blue histiocyte.

Syndrome of the sea-blue histiocyte.


Infectious hepatitis and Down's syndrome.


Medical care in the United States.

Medical care in the United States.


Control of lymphocyte level in the blood.


Effect of psychotomimetic agents on sex ratio?


Regular haemodialysis and renal transplantation.


Occult blood.

Occult blood.


Platelet adhesiveness in Hageman trait.

Platelet adhesiveness in Hageman trait.


Milk-bottle problem.

Milk-bottle problem.


Design of skin flaps.

Design of skin flaps.


Severe hypoglycaemia after glibenclamide.


Robert Francis Jack Henry, M.B. Dubl., F.R.C.S.I.


Automatic hand viewers and cassette play-back units.


Learning carrels in a clinical course.

Learning carrels in a clinical course.


Individualized instruction for the college curriculum.


Diffuse cutaneous leishmaniasis in Ethiopia. 3. Immunological studies. IV. Pathogenesis of diffuse cutaneous leishmaniasis.


Remarks to the haemogram of the pheasants.


Effect of macrophage engulfment and temperature on the transformation process of Leishmania donovani.


The fine structure of human somatic chromosomes studied by  scanning electron microscopy and the replica method.


Inactivation of "Arvin" by plasma proteins.


Studies on comparison of staining of Treponema pallidum with that of Borrelia recurrentis as seen from long-term preservation of the specimen. I. Positive staining.


A contribution to staining of Treponema pallidum in tissue. II. Concentration of silver nitrate solution suitable for staining of Treponema pallidum in tissue.


Fluorescence in skin cancer showing verruca senilis in appearance.


A contribution to staining of Treponema pallidum in tissue. I. Staining of Treponema pallidum in tissue using silver staining solution with surface-active agents.


A contribution to staining of Treponema pallidum in tissue. 3. An evaluation of surface-active agents for staining of Treponema pallidum in tissue.


Application of fluorescent dyes to dermatological investigation. V. Fluorescent microscopial study of squamous cell carcinoma.


A contribution to staining of Treponema pallidum in tissue. IV. Staining of Treponema pallidum in tissue of syphilid in test-rabbit and man.


Application of fluorescent dyes to dermatological investigation. VI. Fluorescent microscopical study of precancerous state and basal cell carcinoma.


Symbolic interaction: analysis of listening.


Comparison of video-tape and face-to-face interviewing.


Computerized data analysis of hemodialyzers by a standard protocol shows true effective membrane area.


Multiple antibody response following busulfan therapy.


Desmosomes and hemidesmosomes in the flagellate Crithidia fasciculata.


Ultrastructural studies of spontaneous spermiation in the guinea pig.


Fine structure of pars neuro-intermedia of the loach, Misgurnus fossilis L.


Fine structure of the vessels of the hypophysial portal system of the white-crowned sparrow, Zonotrichia leucophrys gambelii.


I-125 labelled thyroid hormones in cultured mammalian nerve tissue.


On surgical treatment of prostatic hyperplasia.


Malaria: host-defense mechanisms and complications.


Methodological observations on the histochemical demonstration of glycogen phosphorylase activity.


The bile canaliculi in experimental liver disorders. A cytochemical study in guinea pigs.


Effect of anaesthesia on the behaviour of exogenous 5HT in area postrema of rat and mouse brain studies by fluorescence microscopy.


Sarcoidosis with atrophic lesions and ulcers and the presence in some sarcoid granulomata of orceinophil fibres.


An unusual variant of lupus erythematosus or lichen planus.


The cell surface coat of normal keratinocytes and of acantholytic keratinocytes in pemphigus. An electron microscopic study.


Symbolism in the treatment of schizophrenia.


Human fascioliasis in Shropshire.

Human fascioliasis in Shropshire. Five patients with fascioliasis presented with malaise, pruritus, and pain in the right hypochondrium. Eosinophilia, increase in serum gamma globulin, and pyrexia were other features. Four patients treated with oral bithionol recovered completely and it is suggested that this is an effective form of therapy. The double diffusion precipitin test, being speedy and simple, was used as a screening procedure for diagnosis. The source of infection was wild watercress growing in a farm ditch.


Propranolol and serum calcium in thyrotoxicosis.


A controlled trial of three regimens of self-administered and supervised chemotherapy for pulmonary tuberculosis. A. General report.


Emetine myopathy.

Emetine myopathy.


Investigation of the symbolic self using the concentric circles method and animal metaphor.


Authoritarianism among white and black deaf adolescents: two measures compared.


Antineuronal antibodies in patients having myasthenia gravis.


Biosynthesis of gramicidin S.

Biosynthesis of gramicidin S.


Electron microscopy of enzymes.

Electron microscopy of enzymes.


The cell population in pancreatic islets of Amphisbaenidae--a light and electron microscopic study.


Clinicopathologic study of 53 cases of Brenner's tumors of the ovary.


Morphology of alveolar lining layer.

Morphology of alveolar lining layer.


Fine structural study of rat molar cementum.


A histochemical and fine structural study of early extracellular connective tissue in the chick embryo.


Brunner's glands of the echidna.

Brunner's glands of the echidna.


Advances in asthma. Hypersensitivity mechanisms.


Immunospecificity of fluorescein-conjugated anti-human beta 1C-globulin method for detection of cell-bound antibody.


Specific inhibition of acid phosphatase-3 in pollen of maize by the diazonium salt fast garnet GBC.


Histochemical azo coupling reactions of the pigments of obstructive icterus and of hematoidin. I. Diazonium salts used.


Exogenous cytochrome c as an ultrastructural tracer.


Fluorescent nuclear staining with europium thenolytrifluoroacetonate.


An introduction to electrocardiography by an automatic audio-visual technique.


Measles (rubeola) in previously immunized children.


Am(1), the first genetic marker of human immunoglobulin A. The genetic markers of human immunoglobulins have significantly contributed to the understanding of the molecular biology of antibody synthesis. Like the Gm markers of IgG, the first genetic marker of serum IgA, a major immunoglubulin of exocrine secretions, has now been defined and termed Am(1). It is inherited as a Mendelian dominant trait and is independent of the Gm and Inv allotypes. Am(1) is localized in the alpha-chains of the gammaA(2) subclass and is independent of the serum gammaA(2) levels. Its polymorphism makes it suitable for studies in population genetics and the molecular biology of IgA globulin.


Properties of halves of immunoglobulin light chains. Light polypeptide chains from both normal human gammaG immunoglobulin and Bence-Jones proteins can be cleaved into halves by limited proteolysis with trypsin, pepsin, or papain. The fragments were obtained in yields of up to 22 per cent, had molecular weights of 10,000 to 11,000, and were shown by amino acid analysis and antigenic analysis to correspond to variable or constant regions of light chains. Starch gel electrophoresis in urea suggested that each half consisted of a single polypeptide chain. A fragment from the urine of a myeloma patient corresponded almost exactly to the constant half of a gamma-chain and had a compact shape (Stokes radius of 16 A; frictional ratio of 1.1). Similar Stokes radii were estimated both on fragments from normal urine and fragments produced by proteolysis of normal light chains. The results are consistent with the view that most urinary fragments have a catabolic origin and suggest that there is a small stretch of polypeptide chain between the compact V and C regions of light chains which is particularly susceptible to proteolysis. This lends support to the hypothesis that immunoglobulin chains consist of globular domains connected by more extended stretches of polypeptide chain.


Allergic protein-losing gastroenteropathy: report of an unusual case.


Intracellular staining of physiologically identified interneurones in the cat spinal cord.


Suppurative parotitis in children.

Suppurative parotitis in children.


Sudden unexpected death (SUD).

Sudden unexpected death (SUD).


The effects of d-tubocurarine on spontaneous postganglionic sympathetic activity and histamine release.


Dual staining of some sulfated mucopolysaccharides with alcian blue (pH 1.0) and ruthenium red (pH 2.5).


A simplified benzoylation-diazonium coupling sequence for demonstrating conjugated proteins.


Effects of low concentrations of thyroid stimulating hormone: pharmacological experiments in vitro.


Treatment of toxic nodular and diffuse goitre with radioactive iodine. Late results and use of carbimazole.


Effects of continuous daily administration of 0.3 mg of norehtindrone on the plasma levels of progesterone and on the urinary excretion of pregnanediol and total oestrogens.


Demonstration of splenic metallophilic cells in bacterial infectious disease.


Selective injury of mitochondria with Janus green B and ruby laser light--enzyme morphological and ultrastructural study.


Experimental amyloidosis induced by immune complex or heat denatur ed DNA. I. An electron microscopic observation.


Interaction, a teaching tool in chemistry education.


Simplified method for estimation of serum and plasma viscosity in multiple myeloma and related disorders.


Albumin and IgG turnover studies in patients with cirrhosis.


Immunoglobulin M (IgM) turnover in hepatitis.


The effects of azathioprin in patients with cirrhosis of the liver.


Alcoholic hepatitis in the spectrum of ethanol-induced liver injury.


Modeling and transfer of composed bone autograft in tubed flap--in experiment.


Neurofibromatosis of the head.

Neurofibromatosis of the head.


New method of plastic operation of pharyngoesophageal tract in case of extensive laryngectomy because of cancer.


Contribution to the research of malformations on the hands.


The task of sex and age in formation of Dupuytren's contracture.


Results of tubed pedicle flap plasty in large and complicated eyelid defects.


Transplantation of homologous cartilage sterilized in formalin vapours. (Preliminary report).


In memoriam Frantisek Burian, the founder of the Czechoslovak plastic and reconstructive surgery.


Histamine release inhibition in anti-inflammatory mechanism.


Binding of photosensitizing dyes with some biopolymers.


Ultrastructure and distribution of neuronal and glial elements on the motoneuron surface in the lumbosacral spinal cord of the adult cat.


Diagnosis of beta thalassaemia in the newborn by means of haemoglobin synthesis.


Fetoprotein and albumin levels in the blood serum of developing neonatal pigs.


Comparative circular dichroism studies of individual eel and human antibodies.


Immunoglobulin formation and function in different tissues.


Special aids for the 1971 National Children's Dental Health Week. Bureau of Dental Health Education.


Perfusion of the superior cervical ganglion of the cat with anti-permeable substance.


The assessment of thyroid function by in-vitro techniques. A comparison of commercial kits.


The bile canaliculi in cytological aspiration biopsies from patients with liver disorders.


Rheumatoid-factor-like substance and antistreptolysin O antibody in leprosy serum. Significance in erythema nodosum leprosum.


Method for permanent in situ display of retinal nerve fiber layer anatomy.


Leprosy. II. IgA and IgM immunoproteins in leprosy sera.


Acute schistosomiasis Mansoni in 10 boys. An outbreak in Caguas, Puerto Rico.


Thyrotoxicosis presenting as choreoathetosis.


Leprosy. 3. A comparison of IgA and IgM immunoproteins of patients with pulmonary tuberculosis and leprosy.


Cytochemical electron microscopic localization o esterase activity in Lactobacillus casei. Enzymes capable of hydrolyzing thiolacetic acid in two strains of Lactobacillus casei were localized by the formation of electron-opaque PbS deposits in vivo in the presence of Pb(NO(3))(2). By electron microscopy, the deposition of PbS appeared primarily at the plasma membrane and at the outer surface of the cell wall.


Nuclear distribution in the mycelium of Claviceps and the problem of strain selection. Cytological studies of the developing mycelium of Claviceps suggest that genetic uniformity may be obtained in strains derived from single spores.


Infiltrative diseases of the small bowel and malabsorption.


Application of freeze-etching method to the study of reovirus-infected LLC-MK2 cells. A continuous cell line of rhesus monkey kidney cells, LLC-MK(2), was infected with reovirus type 1 (Lang). The cells were freeze-etched as a method for observing the structural details of the reovirus-induced cytoplasmic inclusion. Information on maturation may be obtained by preparing infected cells for electron microscopy by freeze-etching.


Volutin granules in Zoogloea ramigera.

Volutin granules in Zoogloea ramigera. Zoogloea ramigera, a gram-negative bacterium found in activated sludge, formed volutin granules when excess orthophosphate was added to a phosphate-starved culture. These volutin granules were stainable by hydrogen sulfide after lead acetate treatment and extractable by N-perchloric acid but were not adsorbed by activated charcoal. They appeared to consist of inorganic polyphosphate. Optimum granule formation in the arginine broth required 10 g of glucose, 3 mg of phosphate, and 1 to 20 mg of magnesium per liter of medium. At an Mg(2+) concentration of 1 mg/liter, very large granules appeared which often appeared to fill the cell. An excess of glucose, orthophosphate, or magnesium reduced granule formation. In the absence of sulfate, moderate granulation occurred in arginine broth before the addition of excess orthophosphate; granulation did not increase after the addition of phosphate.


Lanthanum staining of Langerhans' cell. Communication of Langerhans' cell granules with extracellular space.


Formalin pigment in skin.

Formalin pigment in skin.


Macromolecular assemblies of lipid in bile.


Immunofluorescent localization of mammary tumor virus antigens in mammary tumor cells in culture.


Localization of two species specific antigenic determinants on the peptide chains of calf skin collagen.


Role of erythrocyte destruction products in the mechanism of erythropoiesis autoregulation.


Antigenicity of polypeptides (poly alpha amino acids): calcium-dependent and independent antibodies.


Independence of allotypic determinants and antibody specificity.


Delayed hypersensitivity to insulin and its component polypeptide chains.


Quantitation of canine immunoglobulins.

Quantitation of canine immunoglobulins.


Structural studies of immunoglobulin E. II. Amino terminal sequence of the heavy chain.


The evolution of the immune response. VII. Antibody to human "O" cells and properties of the immunoglobulin in lamprey.


Measurement of IgA levels in human cord serum by a new radioimmunoassay.


Senate wins clean car race.

Senate wins clean car race.


Iodination and the biological activity of gastrin.


Anthropological significance of gamma globulin (Gm and Inv) antigens in Bougainville Island, Melanesia.


Mixed lymphocyte cultures and HL-A identity in unrelated subjects.


In vitro sensitization of mouse peritoneal mast cells with reaginic antibody.


Conservative management of genial tubercle fractures.


A phantom head for teaching dental radiography.


Bubble chamber pictures as a means of demonstrating radiation distribution in biological systems.


Silver staining of micro- and oligodendroglia by means of physical development.


Silver staining of fibrous neuroglia by means of physical development.


Morphological studies of the neural spread of herpes simplex virus to the central nervous system.


Comparison of various drug regimens in domiciliary chemotherapy.


Pneumocystis carinii infection. A cytologic, histologic, and electron microscopic study of the organism.


Histochemical staining of normal and Mycoplasma-infected turkey sinus epithelial cells.


Renal transplantation: present status.

Renal transplantation: present status.


The effect of the carrier protein on the immune response and on the induction of tolerance in mice to the 2,4-dinitrophenyl determinant.


Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. II. Studies with fluorescent antibody technique.


Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. I. Light microscopic study.


Antibody production in vitro. The effects of anti-allotypic serum on the secondary response of rabbit spleen cell suspensions to sheep erythrocytes (SRC).


The recovery of immunological reactivity to some synthetic polypeptides containing proline after the induction of specific immunological tolerance.


Studies on intravitreal initiation of the immune response.


Auto-allergic reactions following internal irradiation of the liver.


The archetypes in Peter Pan.

The archetypes in Peter Pan.


The symbolic attitude in psychotherapy.

The symbolic attitude in psychotherapy.


The acid-base surface: a three-dimensional visual model for analysis of acid-base information.


Changing morphology of the uterine tubes of the domestic pig (Sus scrofa domesticus) with age.


Non-production of interfering substances by serum from patients with infectious hepatitis.


The significance of intermediate fibres in reinnervated human skeletal muscle.


Effects of maternal dietary lipotropes on prenatal and neonatal rats.


Ultrastructural and histochemical correlations of experimental muscle regeneration.


Detection of a new serum-antigen in three epidemics of short-incubation hepatitis.


Care and management of a chimpanzee after cross-circulation with a hepatitis patient.


HL-A matching in treatment of burned patients with skin allografts.


Prenatal observations on the incisive fissure and the frontal process in man.


Central venous pressure in clinical management of acute gastrointestinal bleeding.


Stimulation of pancreatic secretion by intraduodenal infusion of bile-salts.


Hypokalaemia in megaloblastic anaemias.

Hypokalaemia in megaloblastic anaemias.


Short-term anaphylactic IgG antibodies in human sera.


Amitriptyline and cardiac disease. Risk of sudden death identified by monitoring system.


Leucocyte antigens and placental sponge.


The at-risk register.

The at-risk register.


Lymphoid stimulation and lymphoid neoplasia.


Urinary oestrogens in pill-users may be artefacts.


Amyloidosis of Alzheimer's disease: a clue to ageing?


Compartmentalisation of ascitic fluid.

Compartmentalisation of ascitic fluid.


Neuromuscular disorders in rheumatoid arthritis.


Cutting the cost of health care.

Cutting the cost of health care.


Coordinated care of the child with spina bifida.


Emergency call service.

Emergency call service.


Epidemic Shiga dysentery in Central America.


Population policy.

Population policy.


Sterilisation of women.

Sterilisation of women.


Royal College of Physicians of Edinburgh.


Contamination of operation wounds.

Contamination of operation wounds.


Australia antigen and hepatitis.

Australia antigen and hepatitis.


Junior hospital staff in training.

Junior hospital staff in training.


Thrombolytic therapy in pulmonary embolism.


Prostaglandins in fertility control.

Prostaglandins in fertility control.


Carrageenan and galactosaemia.

Carrageenan and galactosaemia.


Autoimmunity in diabetes mellitus.

Autoimmunity in diabetes mellitus.


Children in isolation units.

Children in isolation units.


Selection of housemen.

Selection of housemen.


The fist as external cardiac pacemaker.

The fist as external cardiac pacemaker.


L-tryptophan in depression.

L-tryptophan in depression.


L-dopa, parkinsonism, and depression.

L-dopa, parkinsonism, and depression.


Exercise and urinary excretion of cyclic A.M.P.


Cheese reaction during debrisoquine treatment.


Post-vagotomy dysphagia.

Post-vagotomy dysphagia.


Vitamin-D treatment in hypoparathyroidism.


Tolbutamide test in pituitary disease.

Tolbutamide test in pituitary disease.


Metabolism of progestagens.

Metabolism of progestagens.


N.B.T. test stimulated.

N.B.T. test stimulated.


Haemoglobin and cholesterol.

Haemoglobin and cholesterol.


Assessing the nutritional status of children.


Stool trypsin assay.

Stool trypsin assay.


Vaccum extraction following cord prolapse.


Milk-bottle problem.

Milk-bottle problem.


Patricia Troy, L.R.C.P.I.

Patricia Troy, L.R.C.P.I.


Influence of ototoxic drugs on acetylcholine-induced depression of the cochlear N1 potential.


Maternal and child health nursing. Nursing therapy in a combined treatment approach to rumination.


Allergy techniques: methods and mechanisms.


Ethanol infusions.

Ethanol infusions.


The overhead projector as a blackboard.

The overhead projector as a blackboard.


Sim: the perfect patient.

Sim: the perfect patient.


Annex I. New agglutination methods for the diagnosis of brucellosis using stained antigens.


Carcinoma of the stomach.

Carcinoma of the stomach.


Ringless needle holder. An aid in training of surgery residents and scrub nurses.


Vibrios from fish pen slime which mimic Escherichia coli on violet red bile agar. Organisms from fish pen slime which mimicked coliforms and Escherichia coli on Violet Red Bile Agar were identified as members of the genus Vibrio on the basis of metabolic and morphological characteristics.


Plaque size heterogeneity: a genetic trait of lymphocytic choriomeningitis virus. All of the ten strains of lymphocytic choriomeningitis virus assayed on BHK 21/13S cells showed various degrees of plaque size heterogeneity. The amount of virus released from these plaques was usually very small because of rapid photodynamic inactivation by neutral red. When virus from large and small plaques of a specific strain was plated, the same distribution of plaque size was obtained from each clone. Although it was shown that surface virus could possibly be randomly distributed at the time of addition of neutral red overlays, no virus could be isolated from nonplaque areas. Two different strains of virus (CA1371 and WE) with markedly different plaque size ranges were separated by plaque excision from plates infected with a mixture of both viruses.


A novel technique for in situ demonstration of cell viability and cell injury on the respiratory surface of trachea explants. Brief report.


Morphological studies on equine arteritis virus.


Guinea pig ovary and testis: localization of common gonad specific antigens.


Detection and some characteristics of foot-and-mouth disease (FMD) antibodies in bovine saliva. Brief report.


Polybenzoid hazards.

Polybenzoid hazards.


Thin-layer chromatographic identification of estrogens and progestogens in oral contraceptives.


Investigations on the fine structure of staphylococcus in relation to its multiplication phases.


Pituitary-adrenal responsiveness during prolonged administration of estrogen and 17-acetoxy-progesterone derived progestin.


Eosinophil leukocytes in inflammatory exudate.


Immunosuppressive treatment of bronchial asthma.


Electron microscopy study of the pox-like virus of Melolontha melolontha L(Coleoptera, Scarabeidae). Virus morphogenesis.


Physicochemical studies of equine infectionus anemia virus. 3. Purification and electron microscopic observation of the virus.


Characterization of bovine viral diarrhea viruses. V. Morphology of characteristic particles studied by electron microscopy.


Electron microscopic studies on bovine ephemeral fever virus.


Electron microscopic observations of equine infectious anemia (EIA) virus in cultivated horse leukocytes. (Brief report).


A respiratory syncytial virus of bovine origin.


Selective staining of degenerating axons in the central nervous system by a simplified silver method: spinal cord projections to external cuneate and inferior olivary nuclei in the cat.


Virus-like particles occurring in cultures of stable pig kidney cell lines. Brief report.


Disappointments in the management of patients with malignancy of pancreas, duodenum, and common bile duct.


Ultrastructural localization of acid phosphatase in synaptic terminals of the rat substantia gelatinosa Rolandi.


Methods in pancreatitis research using living acinar cells.


Presence of gammaE in nasal washings and sputum from asthmatic patients.


Hypersensitivity responses in monkeys. IV. Sensitization to human serum and nonacceptance of reagin.


Immunologic studies on aspirin. Clinical studies with aspiryl-protein conjugates.


Corneal immune globulin distribution.

Corneal immune globulin distribution.


Toxicity of the cyanoacrylates.

Toxicity of the cyanoacrylates.


Slow evoked cortical potentials and temporal features of stimulation.


Dynamic characteristics of visual evoked potentials in the dog. I. Cortical and subcortical potentials evoked by sine wave modulated light.


Dynamic characteristics of visual evoked potentials in the dog. II. Beta frequency selectivity in evoked potentials and background activity.


Chemical sensitivity of neurons in long-isolated slabs of cat cerebral cortex.


Inhibition and paroxysmal activity in long-isolated cortical slabs.


Naso-ethmoidal electrode for recording the electrical activity of the inferior surface of the frontal lobe.


EEG analysis based on time domain properties.


A digitally controlled constant current stimulator.


An improved write-out system for low frequency wave analysers.


Electroencephalographic features of posterior fossa tumours in children.


Changes in the ventricular system and the EEG 24 hours after pneumoencephalography.


Traumatic generalized changes in the EEG.


Unusual EEG findings with subdural hematoma in a child.


Frequency analysis studies on the sleep EEG of older infants.


Treatment of tetanus.

Treatment of tetanus.


A method to determine the efficiency of anti-epileptic drugs on experimental cortical seizures.


Narcotic and excitatory phenomena influenced by the analgesic Fentanyl.


The EEG of congenitally blind adults.

The EEG of congenitally blind adults.


A micro-electrode technique for the comparison of micro-electroencephalograms.


Evoked potentials of different sense modalities in the human thalamus.


Fatigue as a neurological syndrome.

Fatigue as a neurological syndrome.


Pseudomyotonia.

Pseudomyotonia.


Ultrasound measurements.

Ultrasound measurements.


Movements of cerebral structures.

Movements of cerebral structures.


Surface marking cerebral structures in echo-encephalography.


Reflex amplitudes and increasing mental load.


Depth electrographic observations in an epileptic patient.


Effects of acute marijuana smoking on the EEG.


Interrelationships of form and latency of spike discharge from small areas of human cortex.


The EEG in deaf children.

The EEG in deaf children.


EEG study of maturation in the puppy: photic stimulation and CO2.


Analysis of hippocampal influence on units of mammillary region in awake, sitting squirrel monkeys.


Focal high voltage beta activity: clinical correlations.


Cerebellar induced effects recorded in the cochlear nucleus of the cat.


Regional permeability changes in experimental convulsive disorder.


Phasic changes in level of the integrated dark discharge during spontaneous saccades.


Simultaneous bilateral summated cortical responses to single and to variably delayed median nerve stimulation.


Evoked responses in Down's syndrome of young adults.


Lateralized EEG changes after induced convulsions.


EEG in Kleine-Levin syndrome.

EEG in Kleine-Levin syndrome.


XYY and XXY inmates of security prison: EEG findings.


EEG findings in hydrocephalic patients with shunt procedures.


Hypsarrhythmic EEG patterns in the first year of life: a 6-12 year clinical outcome.


Late brain recovery processes after drug overdose.


Occipital spikes during photic stimulation and their relation to visual evoked responses in photosensitive epilepsy.


The use of the autoregressive model in EEG analysis.


The effect of stimulus context on evoked responses in human frontal cortex.


Electro-clinical features of 50 children with tuberose sclerosis.


Investigations for the development of a model of an epileptic process.


Polarity and distribution of human visual evoked potential (VEP) components as clues to cortical topography.


The dendritic tree of spinal neurons.

The dendritic tree of spinal neurons.


Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans.


Effects of gamma-globulin with vaccines used with routine immunizations.


The effects of various physical activity levels and dietary carbohydrate source on rat cholesterol levels.


Sarcomas after inoculation of newborn hamsters with Herpes virus hominis type 2 strains.


Iron in the lactating mammary gland of the rat.


Reactions of proinsulin and its derivatives with antibodies to insulin.


Antibodies to homologous RNA in the rabbit following stimulation by exogenous RNA.


Production of heparin related mucopolysaccharides by mammalian cells in culture.


Diffusion of epsilon aminocaproic acid to the joints.


Antibody-forming cells in five organs of hyperimmunized guinea pigs.


Metabolic neuropathies and myopathies in infancy and childhood.


Uraemic polyneuropathy.

Uraemic polyneuropathy.


Virus-specific immunofluorescent and precipitin antigens and cell-free virus in the tissues of birds infected with Marek's disease.


Correlation of thyroid-function studies.


The regeneration gradients and the effects of budding, feeding, actinomycin and R Nase on reconstitution in Hydra attenuata Pall.


Monoclonal immunoglobulins.

Monoclonal immunoglobulins.


Immunoglobulins in asthma.

Immunoglobulins in asthma.


Cell-mediated immunity. Antigenic specificity.


Antibodies. Structure and function of immunoglobulins.


Antigenic determinants and antibody complementarity.


Animal models of allergic diseases. Monkeys.


The allergic response of rabbit leukocytes and platelets.


Coagulation and fibrinolytic studies during continuous use of low dose gestagen.


Bedside diagnosis of arrhythmias.

Bedside diagnosis of arrhythmias.


Esophagogastrectomy versus radiation therapy for midesophageal carcinoma.


Mechanism of drug action in the therapy of respiratory allergy.


Extracorporeal circulation for support of palliative cardiac surgery in infants.


Proposed guidelines for protocol studies. II. Plasma cell myeloma. Prepared by a Committee of the Chronic Leukemia--Myeloma Task Force, National Cancer Institute.


Development of new instructional materials in the IMC network.


Combinations of agents which induce ATP energized mitochondrial volume changes.


Immunochemical studies on the serum, intestinal secretions and intestinal mucosa in patients with adult celiac disease and other forms of the celiac syndrome.


Aminoalkenylbenzenesulfonamides with hypotensive and histamine-releasing properties.


The demonstration of recent myocardial injury: a simple method suitable for routine use.


Hepatitis-associated antigen in Ugandan patients with hepatocellular carcinoma.


Measurement of rectal electrical potential difference as an instant screening-test for hyperaldosteronism.


Extraskeletal calcification complicating oral neutral-phosphate therapy.


Impaired fibrinolytic response to exercise in patients with type-IV hyperlipoproteinaemia.


Leucocyte phenotypes in Hodgkin's disease.


Duplication of alpha-thalassaemia gene in three Greek families with haemoglobin H disease.


B.C.G. vaccination and leukemia mortality.


To weigh and to consider.

To weigh and to consider.


Amyloidosis: an expression of immunological tolerance?


Screening outpatients for hyperaldosteronism.


Uneasy present, uncertain future.

Uneasy present, uncertain future.


Renal disease in old people.

Renal disease in old people.


Psychological effects of subarachnoid haemorrhage.


The patient's tight.

The patient's tight.


The world's poliomyelitis.

The world's poliomyelitis.


Preoperative and postoperative physiotherapy.


Paying for medical care. Need for debate.


Intradermal test and serological tests in suspected brucella infection in man.


Coping with incontinence in the home.

Coping with incontinence in the home.


Deaths in United Kingdom opioid users 1965-69.


Screening for breast and gynaecological lesions.


Legal abortion and social class.

Legal abortion and social class.


Ineffectiveness of L-dopa as supplement to penicillamine in a case of Wilson's disease.


Side-effects of L-dopa in postencephalitic parkinsonism.


L-dopa plus decarboxylase inhibitor in depression.


Smoking and frusemide diuresis.

Smoking and frusemide diuresis.


Epidemic shiga dysentery in Central America.


Long-term hepatic support.

Long-term hepatic support.


The beta-blocking effect of practolol in asthmatics.


Maternity service.

Maternity service.


Medical care in the United States.

Medical care in the United States.


Fetoprotein in pregnant African women.

Fetoprotein in pregnant African women.


Contamination of meat carcasses.

Contamination of meat carcasses.


Sleep-walking in twins.

Sleep-walking in twins.


Effect of tyrosine on plasma-I.R.I.

Effect of tyrosine on plasma-I.R.I.


Circulating heparin-like anticoagulant following portacaval anastomosis.


Criteria of rheumatic fever.

Criteria of rheumatic fever.


Silastic sheeting for abdominal-wall defects.


Pingelap eye disease.

Pingelap eye disease.


46, XY female: anti-androgenic effect of oral contraceptive?


Fluid-balance charts.

Fluid-balance charts.


Glucose-6-phosphate-dehydrogenase deficiency and age.


Pathogenesis of the glomerular lesions in acute pancreatitis.


Lithium depletion and atherosclerotic heart-disease.


Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin.


Down's syndrome and presbyacousis.

Down's syndrome and presbyacousis.


Acute myeloid leukaemia after treatment with cytostatic agents.


Evolution of an atypical case of Burkitt lymphoma.


The at-risk register.

The at-risk register.


Venereal disease.

Venereal disease.


Tests for syphilis in children for adoption.


Epidemiology of gallstone disease.

Epidemiology of gallstone disease.


Variability in urinary creatinine.

Variability in urinary creatinine.


Negative Coombs tests in Chinese on methyldopa.


Arthur Doyne Courtenay Bell, D.M. Oxon., F.R.C.P.


Amino acid sequence similarities in two human anti gamma globulin antibodies. Certain individuals with hypergammaglobulinemic purpura contain in their serum anti gamma globulins of restricted heterogeneity. These antibodies, characteristically of the gammaG type, were isolated from two unrelated individuals and their light polypeptide chains were subjected to amino acid sequence analysis. Although these anti gamma globulin antibodies conform to the basic VK(1) sequence, substitutions not previously encountered were found in five positions. The two antibodies were identical with each other up to residue 40 from the N-terminus of the light chains.


Correction of celluar metachromasia in cultured fibroblasts in several inherited mucopolysaccharidoses. Cultured fibroblasts from the genetic mucopolysaccharidoses store higher than normal amounts of the polyanionic glycosaminoglycans (mucopolysaccharides); histochemical staining with the cationic dyes toluidine blue O and Alcian blue detects such intracellular accumulation. With these stains as phenotypic markers, correction of the cellular abnormality by fibroblasts derived from different patients and their heterozygous parents has been observed among several genetic types of mucopolysaccharidoses. In this way, syndromes previously considered clinically homogeneous have been separated into distinct groups.


An ultrastructural investigation of calcium-dependent granules in the rat neuropil.


Demonstration of degenerating climbing fibres in the molecular layer of the cerebellum.


Staining of experimentally-induced chorio-retinal lesions with Disulphine blue and Evans blue.


New data and concepts concerning the ventricular gradient.


Effect of r-epinephrine-impregnated retraction cord on the cardiovascular system.


Improved methods for calcium and magnesium in epidermis.


Cognitive factors in perceptual dysfunction.


Developmental dyslexia: a constitutional disorder of symbolic perception.


The cardio-thoracic unit. Tan Tock Seng Hospital.


Kinins, kininogen and kininogenase activity in pregnancy and hepatic failure.


The Golgi apparatus in chick corneal epithelium: changes in intracellular position during development. The intracellular position of the Golgi apparatuses in the basal cell layer of the corneal epithelium in embryonic and hatched chicks has been studied in the light microscope by impregnating the Golgi apparatus with silver. During two distinct periods in development the Golgi apparatuses in the basal cells shift from an apical to basal position. Each of these periods correlates in time with the appearance of an acellular collagenous matrix beneath the epithelium. Examination of the basal epithelial cells in the electron microscope confirms the intracellular shifts in position of the Golgi apparatus. The results suggest that the Golgi apparatus shifts to the basal cell pole of the corneal epithelium in order to excrete connective tissue materials into the developing corneal stroma.


Low-resistance junctions between cancer cells in various solid tumors. Electrical coupling, which reveals the presence of specialized low-resistance intercellular junctions, has now been found in four types of tumors, Sarcoma 180, Novikoff hepatoma, and Morris hepatomas 3924-A and 7777. Coupled cancer cells were distinguished from coupled normal cells by intracellular marking techniques. Although the evidence suggests that coupling may be extensive in some cases, it is not possible to say that the coupling was normal. In particular, the results do not exclude less obvious defects in the specialized junctions, such as abnormal distribution or decreased permeability to molecules other than small inorganic ions. The results are discussed in relation to previous studies of coupling in Novikoff hepatomas and in cultures of S1801 and II cell lines.


The structure of collagen--an X-ray study.


Substructure of microtubules in brain nerve cells as revealed by ruthenium red.


What price non-touch technique?

What price non-touch technique?


The ultrastructure of the skin of human embryos. VII. Formation of the apocrine gland.


Epidermal multinucleated giant cell in parapsoriasis guttata and eczematous dermatitis.


Experimental pruritus in the unaffected skin of patients with different itching dermatoses.


Plethysmographic recordings of skin pulses. II. Piezoelectric and photoelectric measurements in psoriasis.


Studies on histamine release from skin and from peritoneal mast cells of the rat induced by heat.


Skin clearance of iontophoretically administered chromium (51Cr) and sodium (22Na) ions in the guinea pig.


Lymph-node permeability factor: a mediator in delayed hypersensitivity? Experiments using the skin window technique.


Delayed reactivity to bacterial and viral extract(s) in different dermatoses.


Terminology of contact dermatitis.

Terminology of contact dermatitis.


Lupus erythematosus. Analysis of the sex- and age-distributions of the discoid and systemic forms of the disease in different countries.


The use of standard serological tests for syphilis in screening for auto-immune connective tissue disease. Chronic biological false-positive reactions and anticomplementary activity.


Linear telangiectasia.

Linear telangiectasia.


Benign gonococcal sepsis. A report of 36 cases.


Sensitivity to antibiotics of N. gonorrhoeae isolated in 1966 and 1968 from patients in North Sweden.


Non-venereal sclerosing lymphangitis of the penis. A clinicopathologic treatise.


The American Association of Orthodontists Audio-Visual Library.


Studies on the serum binding of vitamin B 12 in the newborn human infant.


Effect of epsilon aminocaproic acid (EACA) on lysis of subcutaneous clots.


The neural control of the contractile mechanism in skeletal muscle.


Totipotency, variation and clonal development of cultured cells.


The pineal gland.

The pineal gland.


OR technicians. 1.

OR technicians. 1.


Morphactins.

Morphactins.


Fetal erythrocytes in maternal circulation after spontaneous abortion.


The mechanism of action of gonadotrophic hormones in amphibians: the stimulation of delta5-3beta-hydroxysteroid dehydrogenase activity in testes of Xenopus laevis Daudin.


Electron microscopic study of intranuclear glycogen.


Functional autonomy in multinodular goiter.


Mycoplasma and rheumatoid arthritis.

Mycoplasma and rheumatoid arthritis.


Studies of histamine release from human leukocytes.


Role of the thyroid hormone system in suppression of anaphylaxis due to electrolytic lesion of the tuberal region of the hypothalamus.


Nonspecific passive desensitization. XVI. Type O gamma globulin prevents desensitization by types A, B and AB gamma globulins.


Abnormal eosinophils, eosinophilia and basophilia in methimazole neutropenia.


Effectiveness of topical nasal decongestants.


The role of audio-visual aids in education.


The relationship of complement to allergic disease.


Reliability and convergent validity of a symbolic test for authoritarianism.


Development genetics of the lactate dehydrogenase isozymes of fish.


Prevention of posttransfusion hepatitis by gamma-globulin. Preliminary report.


Sheep, minks, savages and presenile dementia. The story of slow viruses.


Structures of schizophrenic forms of expression.


Typical findings in pathological grief.

Typical findings in pathological grief.


Human secretory immunoglobulins. I. Salivary secretions from individuals with normal or low levels of serum immunoglobulins.


Analysis of results of the 1969 comprehensive chemistry survey of the College of American Pathologists.


Invasion of cartilage by an experimental rat tumor.


Low protein intake and response to Escherichia coli 055 infection in patas monkeys.


Microspectrofluorometric comparison of acridine orange dye binding in meristematic and parenchymal nuclei of the orchid embryo.


Microscopic evaluation of the effects of some vital staining agents on growing bone in rabbits.


A new virus in a spontaneous mammary tumor of a rhesus monkey. This study investigated the ultrastructure and development of virus particles detected in a spontaneous mammary tumor of an 8 year old rhesus monkey.  During a 3-month period of tumor growth, several biopsies were performed.  Thin section electron microscopy of the tumor tissue revealed 2 types of particles:  1) an intracytoplasmic, electron-dense, ring-shaped particle, and 2) an extracellular particle with an outer unit membrane and a central dense nucleoid.  The intracytoplasmic development and virus maturation by a process of budding at the level of the cell membrane was reconstructed.


Histological staining properties of procion yellow M4RS.


Chlorphenesin: a new inhibitor IgE-mediated histamine release.


Cytoplasmic inclusions and nuclear changes in cells infected with influenza-B viruses.


The experimental infection of calves with bacteriaemia-producing strains of Escherichia coli: the influence of colostrum.


The laboratory diagnosis of vaginal infections caused by Trichomonas and Candida (Monilia) species.


The pathogenesis of Sendai virus infection in the mouse lung.


Substructure in negatively stained flagella of Pteridium spermatozoids.


Fine structure of early cartilage calcification.


Structural differences between old and young negatively stained red cell membranes.


A study of the anatomy of the prostate, prostatic urethra and the urinary sphincter system.


Lethal freezing temperatures of the surgical capsule and cryosurgery of the prostate.


The transurethral resection reaction secondary to intraperitoneal extravasation of irrigating solution.


Cellular compartmentalization of herpesvirus antigens during viral replication. HEp-2 cells infected with herpes simplex virus develop five distinct immunofluorescent elements. Three (small nuclear granules, large nuclear granules, and an amorphous mass filling the nucleus) contain antigens which react with a rabbit serum prepared against boiled infected cell debris. A labeled pool of human antibody revealed antigens making up cytoplasmic granules and those responsible for a diffuse cytoplasmic fluorescence. All five immunofluorescent elements are demonstrable with a rabbit serum prepared against unheated infected cell debris. Viral antigens are segregated in the nucleus or in the cytoplasm; within the limits of detection, each antigen accumulates in one compartment only. The antigens responsible for the diffuse cytoplasmic fluorescence and for the amorphous nuclear mass are synthesized early in infection; they are formed in arginine-deprived cells and exist in a form which does not sediment on centrifugation at 79,000 x g for 2 hr. The antigens comprising the nuclear and cytoplasmic granules arise relatively late in infection; they are not formed in arginine-deprived cells, and they are readily sedimented on centrifugation at 79,000 x g for 2 hr. Heating (60 C for 2 hr) confers on one or more cytoplasmic viral antigens a new specificity; the altered antigens are demonstrable with labeled rabbit anti-boiled infected cell serum which normally does not combine with cytoplasmic antigens.


A histochemical and ultrastructural study of intimal bodies of horse arterioles.


Levitation in treatment of large-area burns.


Reovirus-directed ribonucleic acid synthesis in infected L cells. Reovirus replication in L-929 mouse fibroblasts was unaffected by 0.5 mug of actinomycin per ml, a concentration which inhibited cell ribonucleic acid (RNA) synthesis by more than 90%. Under these conditions of selective inhibition, the formation of both single-stranded and double-stranded virus-specific RNA was detected beginning at 6 hr after infection. The purified double-stranded RNA was similar in size and base composition to virus RNA and presumably was incorporated into mature virus. The single-stranded RNA formed ribonuclease-resistant duplexes when annealed with denatured virus RNA but did not self-anneal, thus indicating that it includes copies of only one strand of the duplex. The single-stranded RNA was polyribosome-associated and may function as the virus messenger RNA. Production of both types of virus-induced RNA required protein synthesis 6 to 9 hr after infection. At later times in the infectious cycle, only double-stranded RNA synthesis was dependent on continued protein formation.


Long-term results with iodine-125 treatment for toxic diffuse goitre.


Long-term continuous intracranial-pressure monitoring by means of a modified subdural pressure transducer.


Probability of a woman with advanced breast cancer responding to adrenalectomy or hypophysectomy.


Rapid diagnosis of influenza by immunofluorescent techniques.


Lead and delta-aminolaevulinic acid dehydratase levels in mentally retarded children and in lead-poisoned suckling rats.


Natural gas: friend or foe?

Natural gas: friend or foe?


Occupational health: the next move?

Occupational health: the next move?


Treatment of chronic hypoxaemia.

Treatment of chronic hypoxaemia.


Experiments on living animals.

Experiments on living animals.


Impasse.

Impasse.


Cytological examination of endometrium.

Cytological examination of endometrium.


Printing of The Lancet.

Printing of The Lancet.


After the earthquake.

After the earthquake.


Regional service for acute and chronic dialysis of children.


Ten years of boarding-out in Somerset.

Ten years of boarding-out in Somerset.


Immunosurveillance and cancer.

Immunosurveillance and cancer.


Increasing frequency of a syndrome of multiple osseous defects?


Therapeutic abortion by local administration of prostaglandin.


Social work in general practice.

Social work in general practice.


S.H. antigen and chronic liver disease.

S.H. antigen and chronic liver disease.


Liver disease in ulcerative colitis.

Liver disease in ulcerative colitis.


Muscle relaxation during anaesthesia.

Muscle relaxation during anaesthesia.


Caesarean section under local anaesthesia.


Fatal massive liver necrosis after repeated methoxyflurane anaesthesia.


Severe myositis during recovery from influenza.


Treatment of Parkinsonism with L-dopa and amantadine.


Mental symptoms in parkinsonian patients treated with L-dopa.


L-asparaginase and pancreatitis.

L-asparaginase and pancreatitis.


In-vitro cytotoxicity of L-asparaginase on rodent and human neoplastic cells.


Detection of bacteriuria.

Detection of bacteriuria.


Blood-groups, cholesterol, and myocardial infarction.


Effect of dietary fats and carbohydrates on serum-lipids in the rat.


Amitriptyline and cardiac disease.

Amitriptyline and cardiac disease.


Tropical sprue in the Caribbean.

Tropical sprue in the Caribbean.


Chronic diarrhoea and marasmus.

Chronic diarrhoea and marasmus.


Lymphocyte transformation in coeliac disease.


Lactose intolerance following measles.

Lactose intolerance following measles.


Carrageenan and the human gut.

Carrageenan and the human gut.


The at-risk register.

The at-risk register.


Glomerular lesions in acute pancreatitis.


Recurrence risks for cleft lip and cleft palate in British Columbia Indians.


Medical care in the United States.

Medical care in the United States.


The handless and footless families of Brazil.


Long-term remission in acute leukaemia.

Long-term remission in acute leukaemia.


Toxicity of dithiothreitol.

Toxicity of dithiothreitol.


Adam Patrick.

Adam Patrick.


Hypothalamo-pituitary-adrenal function in asthmatic patients receiving long-term corticosteroid therapy.


Acetone in diabetic ketoacidosis.

Acetone in diabetic ketoacidosis.


Small blood-vessels in migraine.

Small blood-vessels in migraine.


Delayed psychosis due to L.S.D.

Delayed psychosis due to L.S.D.


Familial sideroblastic anaemia: problem of Xg and X chromosome inactivation.


Serum gamma-glutamyl transpeptidase as a diagnostic aid.


Heparin treatment for post-partum renal failure with microangiopathic haemolytic anaemia.


Role of myocardium in the modern epidemic of ischaemic heart-disease.


Combined treatment of leukaemias and reticuloses.


Lung cancer in haematite miners.

Lung cancer in haematite miners.


Like gout.

Like gout.


Amantidine and influenza in general practice.


The McMaster medical school at Hamilton, Ontario.


Trimethylaminuria: the fish-odour syndrome.


Burkitt lymphoma and malaria.

Burkitt lymphoma and malaria.


E.B. virus and lymphomas.

E.B. virus and lymphomas.


Leucocyte phenotypes in Hodgkin's disease.


Human lymphoid cell lines: potential hazards to laboratory workers.


Intranuclear aggregates in the liver of a patient with serum hepatitis.


Iron therapy for haemodialysis patients.


Acute myeloid leukaemia after treatment with cytostatic agents.


Coagulation abnormalities in generalised herpes-simplex infection of newborn.


Triethylene tetramine dihydrochloride in Wilson's disease.


Sea-blue-histiocyte syndrome.

Sea-blue-histiocyte syndrome.


L-tryptophan in depression.

L-tryptophan in depression.


Contaminated antiseptic solutions.

Contaminated antiseptic solutions.


The choroid plexus in African sleeping-sickness.


Beta-blocking effect of practolol in asthmatics.


Perinatal mortality.

Perinatal mortality.


Plasticisers from P.V.C.

Plasticisers from P.V.C.


Tetraploidy in cells cultured from amniotic fluid.


Sympathomimetic agents and serum-lipid levels.


Intrauterine administration of prostaglandins.


Lactic acidosis in diabetic coma.

Lactic acidosis in diabetic coma.


Solutions for kidney storage.

Solutions for kidney storage.


Amyloidosis, Alzheimer's disease, and ageing.


Phenformin and blood-urea.

Phenformin and blood-urea.


Rubella and rheumatoid arthritis.

Rubella and rheumatoid arthritis.


Trisomy 18.

Trisomy 18.


Epileptic death due to suffocation during sleep.


Treatment of nephroblastoma and neuroblastoma: M.R.C. trials.


Leg-vein thrombosis following myocardial infarction.


Klebsiella in faecal flora of renal-transplant patients.


Seasonal incidence and mortality of ischaemic heart-disease.


Sciatica caused by sacral-nerve-root cysts.


Metabolic findings in hyperosmolar, non-ketotic diabetic stupor.


Bacteria in faeces and food.

Bacteria in faeces and food.


Fundamental physiological role of parathyroid hormone in acid-base homoeostasis.


Thyroid-function tests.

Thyroid-function tests.


Making plans.

Making plans.


Delayed overture.

Delayed overture.


Safer roads?

Safer roads?


The last of the sixties.

The last of the sixties.


Apathetic thyrotoxicosis.

Apathetic thyrotoxicosis.


More than enough.

More than enough.


Tasmania's medical school.

Tasmania's medical school.


The relief operation in former Biafra.

The relief operation in former Biafra.


Audiovisual aids in medical schools.

Audiovisual aids in medical schools.


Experiments on living animals.

Experiments on living animals.


Blood-groups and hypopharyngeal cancer.

Blood-groups and hypopharyngeal cancer.


Immune responses in malaria.

Immune responses in malaria.


Social work in general practice.

Social work in general practice.


Use of the casualty department.

Use of the casualty department.


Emergency call service.

Emergency call service.