The need for a national policy for the management of inherited metabolic disease.


Focal seizures, early veins, and increased flow. A clinical, angiographic, and radioisotopic correlation. Prominent early draining veins have been found in angiograms of four patients studied during an acute benign illness characterized by repetitive focal motor seizures and prominent postictal neurologic deficits. Concomitant intravenous radionuclide gamma camera flow and static images showed increased relative perfusion with a slight positive static uptake on the involved side. Follow-up studies showed no evidence of these abnormalities. These angiographic and radioisotopic findings probably correlate with the clinically observed cortical hyperemia as part of, or subsequent to, focal motor seizures. Alternatively, these findings suggest the possibility that vascular occlusions may be the underlying cause of the patients' illness.


Inborn errors of metabolism. Vitamin-responsive genetic disease. The several ways in which vitamin administration may bring about a biochemical response in genetic abnormalities have been discussed. Two major interrelated lessons emerge from what we now know about vitamin-responsive genetic disease. First, it is possible to enhance metabolite flow through partially deficient reactions by suitable manipulation of the environment in which a fixed amount of enzyme functions or by changing the concentration of the enzyme itself. The latter approach may be the most versatile in the long run since there may be agents other than vitamins which increase enzyme concentrations. A striking example of such an effect in mammals is furnished by the work of Pitot and his collaborators, who by administration of casein hydrolysate to rats, increased threonine dehydratase activity several hundred-fold (Peraino and Pitot, 1964) by increasing the rate of enzyme synthesis (Jost, Khairallah, and Pitot, 1968). Other means of enhancing enzyme activities, ranging from tissue transplantation to transfer of genetic material, have been discussed elsewhere (for example, see Brady, 1973). These procedures will not be discussed here, other than to mention a recent report (Mukherjee and Krasner, 1973) who transferred several small plugs of liver tissue (approximately 5% of the liver) from normal rats to the livers of rats genetically deficient in bilirubin uridine diphosphate glucuronyltransferase activity. Twelve weeks later the specific activity of glucuronyltransferase had risen in the livers of the recipient rats to 6-23% of normal, and the serum bilirubin of these rats, which had initially been elevated, had fallen to close to, or within, the normal range. Thus liver grafts between suitably matched individuals, may in the near future, become a means of increasing hepatic activities of deficient enzymes to extents which are therapeutically meaningful. The second lesson to be learned from the review presented here is that enhancement of enzyme activity may be therapeutically beneficial even though the increase is small and the activity attained is still reduced relative to normal. It will be well to bear this in mind in any attempts to treat inborn errors of metabolism.


Research support for diagnostic ultrasound.


Lafora's disease: peroxisomal storage in skeletal muscle. A 17-year-old patient had myoclonic epilepsy caused by Lafora's disease. Biopsy showed polysaccharide accumulations within membrane-bound spaces in skeletal muscle cells. Some of the accumulations were morphologically similar to Lafora bodies as they have been seen in the brain. The histochemical reactions of these membrane-bound spaces suggested that they were peroxisomes. Polysaccharide accumulations also were demonstrated in hepatic cells, where they probably were located in the endoplasmic reticulum. Lafora's disease can be diagnosed by histochemical and electron microscopic study of skeletal muscle.


The localized vasomotor and permeability changes at the site of injury which determine the secondary development of permanent damage: the physical approach (cord cooling).


Ultrasound in the diagnosis of hydronephrosis in infants and children.


The sign of the vena cava: echotomographic illustration of right cardiac insufficiency.


Resuscitation and parenteral nutrition in patients with acute spinal cord injuries and associated injuries.


Quantitative echography--the basis of tissue differentiation.


Light-emitting diode device for display of numerical data on any ultrasound oscilloscope.


Mucopolysaccharidoses and mucolipidoses.


The animal experimental model ischemic injuries.


Indications for ultrasonic scanning in abdominal diagnostics.


Echocardiographic determinations of dimensions of normal newborns at 5,280 feet elevation.


Schlieren study of pulsed ultrasound transmission through human skull.


Different standards of presentation used in ultrasound articles.


Echocardiographic diagnosis of calcific stenosis of a stented aortic homograft in the mitral position.


Ultrasonic B-scanning in rhesus incompatibility.


Enhancement of DNA synthesis in neonatal mouse tibial epiphyses after exposure to therapeutic ultrasound.


Ultrasound in twin gestation.

Ultrasound in twin gestation.


The validity of structure identification for cross-sectional echocardiography.


Transmitted ultrasound for relief of obstruction in ureters and arteries: current status.


Ocular neurofibromatosis.

Ocular neurofibromatosis.


Diabetes mellitus in childhood.

Diabetes mellitus in childhood.


Effect of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis.


Genetics of atopic allergy and reagin production.


Mutation frequency decline following chemical mutagenesis of Salmonella typhimurium.


Vernal kerato-conjunctivitis: an allergic disease of the eyes of children.


The genetics and cytology of a mutator factor in Drosophila melanogaster.


A population approach to the study of repair of genetic radiation damage in mature spermatozoa of Drosophila melanogaster.


Mesangiocapillary glomerulonephritis and persistent hypocomplementemia.


Delivery of medical care to isolated communities.


Virology of germfree rodents.

Virology of germfree rodents.


Decreased rate of cytolysis of Colpidium striatum by cystic fibrosis serum. I. Bioassay and evidence for the possible involvement of a C/F factor--IgG complex.


The effect of bovine growth hormone on growth of mammary tumors in hypophysectomized rats.


Antibody production to choline acetyltransferase purified from human brain.


Evolution of enzyme replacement therapy for lipid storage diseases.


Association of diamine oxidase with microsomal membranes in rabbit liver.


Segmental intramural diverticulosis associated with and confined to a spastic area of muscular hypertrophy in a columnar lined oesophagus.


A study of serum nerve growth stimulating activity in patients with neurofibromatosis utilizing a modified bioassay technique.


Anemia and neutropenia caused by copper deficiency.


Hypersensitivity pneumonitis caused by a contaminated cool-mist vaporizer.


Specificity and molecular features of an insect attractant in a Drosophila mutant.


Genetic transfer of the stable L form state to intact bacterial cells.


A family with two siblings affected by Morquio syndrome (MPS IV). Electrophysiological and psychophysical findings in the visual system.


Myasthenic response to muscle relaxants in von Recklinghausen's disease.


Vertigo.

Vertigo.


Drug treatment of Menière's disease.

Drug treatment of Menière's disease.


Labyrinthine surgery for Menière's disease.


Vestibular neuronitis.

Vestibular neuronitis.


Evaluation of post-traumatic vertigo.

Evaluation of post-traumatic vertigo.


Positional vertigo and nystagmus.

Positional vertigo and nystagmus.


The diagnosis and evaluation of acoustic neuromas.


Labyrinthine tap as a diagnostic test for acoustic neurinoma.


Surgery of acoustic tumors.

Surgery of acoustic tumors.


Menière's disease. Etiology, natural history, and results of treatment.


Central vertigo.

Central vertigo.


Basilar-vertebral artery insufficiency as a cause of vertigo.


Diagnostic evaluation of the patient presenting with vertigo.


The antimotion sickness drugs.

The antimotion sickness drugs.


Basic audiometric findings in Menière's disease.


Audiologic tests in the differential diagnosis of vertigo.


The caloric test and its value in evaluation of the patient with vertigo.


Electronystagmography and its value in the diagnosis of vertigo.


Appropriate standard of care.

Appropriate standard of care.


Breakdown of HB 129, HB 130.

Breakdown of HB 129, HB 130.


Rx for professional nursing: the Irvis Report.


Cost control in the delivery of health care services.


Professional nursing and the abortion decisions.


Why nurses leave nursing.

Why nurses leave nursing.


Conventional radiography of the temporal bone.


Tomographic anatomy of the temporal bone.


Tomographic evaluation of cholesteatomas of the middle ear and mastoid.


Otosclerosis.

Otosclerosis.


The diagnosis of acoustic neuromas.

The diagnosis of acoustic neuromas.


Trauma of the ear.

Trauma of the ear.


Congenital malformations of the ear.

Congenital malformations of the ear.


Normal radiographic anatomy of the paranasal sinuses.


Inflammatory diseases of the paranasal sinuses.


Fractures of the paranasal sinuses.

Fractures of the paranasal sinuses.


Cysts, benign tumors, and malignant tumors of the paranasal sinuses.


Sialography and the salivary glands.

Sialography and the salivary glands.


The temporomandibular joint.

The temporomandibular joint.


Radiology of the larynx.

Radiology of the larynx.


Radiological studies of the lymphatic system of the head and neck.


Bronchography.

Bronchography.


Anatomy of the nasal cavities.

Anatomy of the nasal cavities.


Physiology of the nose.

Physiology of the nose.


Olfaction.

Olfaction.


The nasal vasomotor reaction.

The nasal vasomotor reaction.


The "stuffy" nose.

The "stuffy" nose.


Submucous operations on the nasal septum.


Nasal septoplasty.

Nasal septoplasty.


Septal perforations.

Septal perforations.


Nasal Hemorrhage.

Nasal Hemorrhage.


Minor intranasal procedures.

Minor intranasal procedures.


Septal dermoplasty for hereditary telangiectasia and other conditions.


Cerebrospinal fluid rhinorrhea.

Cerebrospinal fluid rhinorrhea.


Atrophic rhinitis.

Atrophic rhinitis.


Choanal atresia.

Choanal atresia.


Nasal fistulas.

Nasal fistulas.


Neoplasms of the nasal cavity.

Neoplasms of the nasal cavity.


Unusual nasal tumors. Problems in diagnosis and treatment.


Rhinomanometry.

Rhinomanometry.


A public concern--a study of the provision of denture services in the delivery of dental health care in Ontario.


Cholinergic mechanisms in aggressive behaviour.


Monohydroxy bile acids in plasma in intrahepatic cholestasis of pregnancy. Identification by computerized gas chromatography-mass spectrometry.


Effect of ventromedial tegmental lesions on central catecholamine neurons of monkey brain: involvement of dopamine pathways in tremor and involuntary movements.


Energy and protein requirements. Report of a joint FAO/WHO ad hoc expert committee. Rome, 22 March-2 April 1971.


Toxicological evaluation of some enzymes, modified starches and certain other substances. Joint FAO/WHO Expert Committee on Food Additives.


Some aspects of prognosis after severe head injury.


Rehabilitation in severe head injuries.

Rehabilitation in severe head injuries.


Controlled ventilation in the management of patients with severe head injuries.


Translational versus rotational acceleration: animal experiments with measured input.


Hydrocephalus following traumatic head injuries.


Evaluation of mental disturbances after head injury.


Cardiac conditioning and extinction in Macaca mulatta during block of the CR by cardiac pacing.


CS intensity effects on rabbit nictitating membrane conditioning, extinction and generalization.


Psychopharmacologic facilitation of operant conditioning of genetically nervous catahoula and pointer dogs.


The effect of tranylcypromine (parnate) on eyelid conditioning and paired associate learning in depressed patients.


Procedure for operant conditioning of the dog.


Hypothesis on the significance of RNA-directed DNA synthesis for evolution.


The rehabilitation of genetically nervous dogs.


Inability to condition a peripheral activating drug.


Altered development of central noradrenaline neurons during ontogeny by 6-hydroxydopamine.


Studies on the intestinal actions of tyramine.


Observations on the concept of neighbourhood knowledge and the distribution of marriage distances.


A group practice approach to sex education.


Genetic markers in chronic myelocytic leukaemia: evidence opposing autosomal inactivation and favouring 6-PGD-Rh linkage.


Emotions and cardiac contractility as reflected in ballistocardiographic recordings.


Long-term conditioned fear modification in the dog as measured by changes in urinary 11-hydroxycorticosteroids, heart rate and behavior.


Clinical value of nerve conduction studies.


The effect of change in US quality on the blocking effect.


Studies of the density and the properties of the hair in a new inherited syndrome of hypotrichosis.


Current trends in infant feeding.

Current trends in infant feeding.


A survey of symptoms occurring in pregnancy.


The probation officer. Part II.

The probation officer. Part II.


Clinical research in cleft lip and cleft palate: the state of the art.


Paediatric nursing: the crying child.

Paediatric nursing: the crying child.


Mother's milk and other home foods.

Mother's milk and other home foods.


Vasectomy. Safe, simple and trouble-free.


Vasectomy. From a patient's viewpoint.

Vasectomy. From a patient's viewpoint.


Vasectomy. Sounding a note of concern.

Vasectomy. Sounding a note of concern.


The sexual problems of doctors.

The sexual problems of doctors.


Nutrition programs in state health agencies.


Food for the growing brain.

Food for the growing brain.


The evaluation of prison treatment and preventive detention programs: some problems faced by the Patuxent institution.


Variations in hormone concentrations in bovine sera used for tissue culture.


Lysinuric protein intolerance.

Lysinuric protein intolerance. Lysinuric protein intolerance is an autosomal recessive disorder which first appears as failure to thrive, vomiting and diarrhea in the infant after weaning from mother's milk. Later it manifests as failure to grow, muscular weakness and osteopenia associated with aversion to animal protein. Some patients become mentally retarded and have periods of stupor. The disease is characterized by marked lysinuria, and hyperammonemia after protein intake. According to accumulating evidence, the basic defect is deficient transport of diamino acids in the intestine, liver and kidney tubuli. Effective treatment is provided by supplementing protein food with extra arginine.


Building standards for the handicapped.

Building standards for the handicapped.


The cause and treatment of low back pain during pregnancy.


The effect of early feeding on the development of obesity.


An ounce of prevention: the Division of Dental Health.


Maternal dehydroepiandrosterone and estrogen production in late pregnancy.


The haemolytic uraemic syndrome.

The haemolytic uraemic syndrome.


The immediate care of thoracic injuries.


Lactic dehydrogenase levels in pernicious anemia.


Primary malignant tumors of the retroperitoneum.


Progress in medicine--a look ahead.

Progress in medicine--a look ahead.


Neurologic manifestations of electrical injury.


The Hippocratic Treatise Peri diaites oxeon.


Dates in the printed editions of the Lilium Medicinae.


Treatment of allergy in children: a double-blind study.


Intracellular enzyme changes in post-anoxic rat brain.


The antigenicity in man of staphlylococcal leucocidin toxoid, with notes on therapeutic immunization in chronic osteomyelits.


A cooling modification to an apparatus for phage typing of Staphylococcus aureus.


Studies on the role of sulfhydryl groups in the biochemical mechanisms of allergic inflammation. 8. Influence of glutathione reductase on reactivation of Arthus-type inflammation by glutathione.


Autosomal mosaicism occurring in conjunction with Down's syndrome.


The sibships posterior to mongoloids.

The sibships posterior to mongoloids.


Cystic acne of infancy.

Cystic acne of infancy.


Follicular mucinosis (alopecia mucinosa).


"A little child shall lead them".

"A little child shall lead them".


The first appointment--a mutual evaluation session.


An investment for the future.

An investment for the future.


Are you just a dentist?

Are you just a dentist?


An evaluation of the efficacy of hydroxyzine (atarax-vistaril) in controlling the behavior of child patients.


Permanent tooth eruption in children with major physical defect and disease.


A simplified radiographic technique for the difficult patient.


The problem of P.T.B. aggravation in compensation cases .


Acne vulgaris.

Acne vulgaris.


The angiogram and pulmonary artery structure and branching (in the normal and with reference to disease).


The skin of primates. XXVI. Specific and nonspecific phosphatases in the skin of the rhesus monkey.


Plasmin and plasminogen levels in pregnancy.


Genetic analysis of T4D phage heterozygotes produced in the presence of 5-fluorodeoxyuridine.


Sickle-cell anaemia in an Indian family in Johore.


Haemoglobin E--thalassaemia in Kelantan.


Agglutinins in normal sera for the typhoid-paratyphoid group of organism.


A review of virus infections of the respiratory tract.


The clinical features, management and treatment of El Tor cholera.


Nocardia asteroides in Malaya.

Nocardia asteroides in Malaya.


A case of renal tubular rickets with absorption defect of glucose and phosphorus.


Sir Richard Brunel Hawes.

Sir Richard Brunel Hawes.


Interdepartmental Committee on Nutrition for National Defence report. Federation of Malaya nutrition survey September--October 1962.


When do we do a breast biopsy?

When do we do a breast biopsy?


Carcinoma of the cervix in Indian women.


Practical aspects of blood coagulation.

Practical aspects of blood coagulation.


Evacuant suppositories in postpartum care.


Neurologic manifestations of injury by ionizing radiation.


Social class and reaction to physical disability.


Child development projects.

Child development projects.


Planning for their future.

Planning for their future.


The factory day at school.

The factory day at school.


Delayed ontogenesis in human trisomy syndromes.


The cost of public health programs in the Philippines.


An experimental biologic approach to the treatment of neoplastic disease; determination of actinomycin in urine and cultures as an aid to diagnosis and prognosis.


Mass screening for diabetes using a skin-surface test.


The role of women physicians in disaster medicine.


Some unusual features in a case of traumatic rupture of the thoracic aorta.


Orthodontic care for children in general practice.


Reactions to nalidixic acid.

Reactions to nalidixic acid.


Barriers in dental practice--architectural and structural.


Phage type and antibiotic sensitivity of staphylococci isolated from monkeys and their human handlers.


Effect of tetracycline on the composition of sebum in acne vulgaris.


Pathologic coronary vessels and regional systolic narrowing of the coronary arteries in hypertrophic obstructive cardiomyopathy.


Tooth ring analysis in mongolism.

Tooth ring analysis in mongolism.


Sedation in dentistry for children: narcotic action.


Cardiomyopathies in children in the tropics.


Fibrinolytic activity and fibrinogen levels in Papuans and New Guineans.


Health survey on a rural Malay population F.L.D.A., Sungai Tekam, Pahang.


Another periauricular abscess from Sarawak, probably caused by a trematode of the genus Poikilorchis, Fain and Vandepitte.


Chondroitin sulfate: inhibition of synthesis by puromycin. Puromycin reversibly inhibits synthesis of chondroitin sulfate by vertebral chondrocytes from 10-day-old chick embryos. Treatment of these cells with puromycin for 5 hours does not affect viability or capacity to multiply on subsequent release from their matrix. It is suggested that synthesis of this polysaccharide is coupled with that of protein; there may be a feedback control in its synthesis.


Myocardial free nucleotides in cardiac hypertrophy.


Adenosinetriphosphatase (ATPase) in the auricular heart muscle in human patients operated upon because of acquired and congenital cardiac defects.


Glycoside-sensitive ATPase from Arachis hypogaea.


Acne, today.

Acne, today.


Treatment of recurrent furunculosis with staphylococcal bacteriophage-lysed vaccine.


Contact dermatitis due to poison ivy, oak, and sumac.


Chronic heart disease due to obesity.

Chronic heart disease due to obesity.


The case of Bill Bum, the burbling bursitic.


Medical care of compensation cases in Indiana.


The forgotten patient: medical management of the multiple handicapped retarded.


This week's offer.

This week's offer.


How to drill kids without actually shooting them.


Management of children under general anesthesia.


Financial implications of leprosy and tuberculosis control in Thailand.


Evasion of responsibility by physicians in planning health services.


A physiological basis for the surgical management of peptic ulceration.


Social reality: a necessary dimension to program.


Significant legislation passed during the 1965 session of the Arkansas legislature.


Placenta accreta.

Placenta accreta.


Multiple causality in psychiatric illness and personality formation. Experimental causation of deviant behavior.


Resurgence of syphilis.

Resurgence of syphilis.


Effects of freezing on the stability of staphylococcal phages.


Spotlighting advances in special education.


Streptomycin sensitization.

Streptomycin sensitization.


The relation of acid mucopolysaccharides and sulfhydryl groups to diseased oral mucosa.


Functions of the cancer cell.

Functions of the cancer cell.


Fibrinogenolytic dysfibrinogenemias.

Fibrinogenolytic dysfibrinogenemias.


Enzymatic effects of fibrinolysin.

Enzymatic effects of fibrinolysin.


Clearance of infused fibrin.

Clearance of infused fibrin.


On the active principles of croton oil. V. Purification and characterisation of further irritant and cocarcinogenic compounds of the B-group.


Staphylococcal infection in the mouse. 3. The effect of survival in infected animals on the mouse virulence of staphylococci.


Surgical correction of inverted nipples.


Breast feeding in today's world.

Breast feeding in today's world.


Mammography in the diagnosis of breast cancer.


Reduction mammaplasty with preservation of nipple-glandular continuity.


Plastic reconstruction of the small breast.


Spinal cord compression secondary to metastatic mammary carcinoma.


Breast feeding and breast disease.

Breast feeding and breast disease.


Changing patterns in education of women.


"In vitro" biosynthesis of androgens by rat submaxillary glands.


Electrocardiographic P wave and atrial weights and volumes.


Electromyographic studies on reflex activity of the intercostal and abdominal muscles in cervical cord lesions.


A uronic and sialic acid free chick allantoic mucopolysaccharide sulphate which combines with influenza virus hi-antibody to host material. 1. Purification of the substance.


Accessory lobe of liver presenting through a congenital deficiency of anterior abdominal wall.


Studies on fibrinogen fractions isolated from human plasma by precipitation with cold ether. I. Plasma kinin formation by the activation of contained plasminogen.


Rupture of the rectus abdominis.

Rupture of the rectus abdominis.


Learning problems of handicapped children.


The ITPA and Down's syndrome: an exploratory study.


Dietary and nutritional problems of crippled children in five rural counties of North Carolina.


Transduction of drug-resistances in Staphylococcus. II. Transduction of chloramphenicol-resistance in both Staphylococcus aureus and Staphylococcus epidermidis by typing phage 80.


Acne vulgaris. Review of one hundred cases.


Treatment of acne.

Treatment of acne.


Treatment of psoriasis, lichen planus, and seborrheic dermatitis.


Treatment of drug eruptions.

Treatment of drug eruptions.


A model of local fibrinolysis (marked elevation of fibrinolytic activity of blood obtained from vasa efferentia of the uterus).


The metabolism of dehydroepiandrosterone in various organs of the rat.


Muscle metabolism as seen in single-twitch experiments.


Studies on testosterone metabolism. IV. Urinary 5-alpha- and beta-androstanediols and testosterone glucuronide from testosterone and dehydrolsoandrosterone sulfate in normal people and hirsute women.


Basic aspects of muscle contraction.

Basic aspects of muscle contraction.


Abdominal muscle involvement during the performance of various forms of sit-up exercise. An electromyographic study.


A case of Norwegian scabies.

A case of Norwegian scabies.


Industrial rehabilitation.

Industrial rehabilitation.


Staphylococcal "lysates" and vaccines.

Staphylococcal "lysates" and vaccines.


Cement dermatitis. II. Clinical aspects.


Antimony spots.

Antimony spots.


Effect of injectable iron-dextran on dairy calves and lambs. Ten Holstein calves, 10 Jersey calves, 7 single lambs, and one lamb from each of ten sets of twins were injected with an iron-dextran solution shortly after birth. These were paired with an equal number of untreated animals that formed the control groups. Percentage of hemoglobin and body weights were recorded periodically up to 16 weeks of age for the calves and 21 weeks for the lambs. Percentage of hemoglobin in the blood of treated calves was generally higher than that of untreated calves but body weights between groups were not significantly different. In the lambs there was no significant difference in percentage of hemoglobin or body weights between the treated and control groups. The results indicate that under the confined system of management as outlined, there was no advantage in administering iron-dextran to young calves or lambs.


Serum fractions inhibitory to the growth of Leptospires. It is known that the growth inhibitory substance of animal sera on Leptospires exists in the albumin fraction. Since the globulin fraction obtained from animal sera having growth inhibitory property may support, though variable individually, some degree of leptospiral growth, it may be added, with 5% of pooled rabbit serum, to the medium to be used for the propagation of Leptospires.


A study of Toxoplasma infection in chickens and cats on a family farm. Presumptive evidence of toxoplasmosis was obtained following histological and serological studies of tissues from chickens and cats kept on a family farm. This was confirmed by transmission of the infection to experimental laboratory animals and back to chickens. The significance of the low grade serological reaction in one of the persons living on the farm was not clear.


Phage patterns of coagulase-positive Staphylococci isolated from dogs. One hundred and thirty-seven coagulase-positive strains of Staphylococcus aureus, isolated from dogs, were tested against three synthetic penicillins (cloxacillin, dicloxacillin, and ampicillin) and also phage typed using bacteriophages which are employed in typing staphylococci isolated from man.


Recommended criteria for cardiac catheterization in patients with aortic valve disease. Criteria for selection of patients with aortic valve disease for cardiac catheterization are described, based on a study of 81 cases. Children with aortic stenosis warrant catheterization at the time when the clinical diagnosis is made, but in adults this examination may be deferred until symptoms appear or left ventricular hypertrophy is recognized. In patients with pure aortic insufficiency catheterization may be deferred until symptoms appear. When severe stenosis and insufficiency co-exist, the valve is usually heavily calcified. Thirty-seven per cent of patients with aortic valve disease have co-existing mitral lesions and these patients are usually women, are fibrillating and, as a rule, have atrial enlargement in contrast to those with aortic valve disease only. On rare occasions, patients with mitral valve disease have clinically silent but angiographically demonstrable aortic insufficiency; therefore, aortography should precede open-heart correction of a mitral lesion so as to detect minor degrees of aortic insufficiency.


Epilepsy and the law.

Epilepsy and the law.


The federal program in the preparation of professional personnel in the education of handicapped children and youth.


Elementary and Secondary Education Act: implications for handicapped children.


The National Defense Education Act and exceptional children.


Research and demonstration program for handicapped children and youth.


Shortcomings of grant applications to the handicapped children research program.


CEC and legislation--now and in the future.


Clearing house: a significant bill becomes law: the Community Mental Health Centers Act Amendments of 1965.


"Teen Town"--exclusive community for exceptional children.


Aplastic anemia, histiocytosis and erythrodermia in immunologically deficient children. Probable human runt disease.


Progestin-estrogen combinations in management of acne.


Intensity of function of structures of the differentiated cell as a determinant of activity of its genetic apparatus.


Studies on the cornea. IV. Some effects of ouabain on pinocytosis and  stromal thickness in the rabbit cornea.


Studies on the fibrinolysis in tumor bearing mice. IV. Mechanism of ascites retention with special reference to plasmin activity of tumor cell origin.


Psychological aspects of physical disability.


Disturbances of acid-base equilibrium resulting from salicylism in children.


Summer in Siam. Report of a Smith Kline and French foreign fellowship to Thailand, June to September, 1964.


Interference and viral infection in a cell line derived from Burkitt's lymphoma.


Permeability of laparotomy sponges to cancer cells.


Forty years of pediatrics.

Forty years of pediatrics.


Marriage ... and medicine.

Marriage ... and medicine.


Conference on criteria for, and evaluation of, orthopedic measures in the management of deformities of rheumatoid arthritis.


Life-threatening drug eruptions.

Life-threatening drug eruptions.


Eye disorders in handicapped children.

Eye disorders in handicapped children.


Dr. Alvin E. Buckwold. An appreciation.

Dr. Alvin E. Buckwold. An appreciation.


Fibrosarcoma of the anterior abdominal wall.


Parental age in Down's syndrome (mongolism).


Effect of radiation on nuclear phosphorylation in human malignant tumours.


Managing the disabled patient.

Managing the disabled patient.


Bacterial urease. A comparison of urease production with coagulase of Staphylococci and fibrinolysin of Pseudomonas aeruginosa.


Incorporation of sulfate-35S, N-acetylglucosamine-1-14C, glucose-1-14C, and galactose-1-14C into calf and beef corneal glycosaminoglycans.


Effects of 'pre-incubation' on the distribution of different enzymes in extracts of Escherichia coli.


The participation of calcium, adenosine triphosphate and adenosine triphosphatase in the extrusion of the granule proteins from the polymorphonuclear leucocyte.


Natural F-actin. I. Direct isolation of F-actin from myofibrils and its physico-chemical properties.


The R-S ratio in lead V2 in the diagnosis of right ventricular hypertrophy.


Water extrusion in isolated subcellular fractions. IV. Simplified system to study the adenosine triphosphate-dependent reaction.


Plasma viscosity in mental deficiency and Down's  syndrome.


Serum seromucoid and acid mucopolysaccharide in malignant neoplastic diseases.


Pyloroplasty and vagotomy in treatment of duodenal ulcers--a preliminary report.


The real self.

The real self.


Glomerulo-nephritis.

Glomerulo-nephritis.


Preparation for international travel.

Preparation for international travel.


Let's sell Arkansas to our medical students and interns.


Whose chromosomes to count in mongolism?


Thyroid disease among children with Down's syndrome (mongolism).


Attitudes as determinants of behavior.

Attitudes as determinants of behavior.


Changing concepts in pedodontics.

Changing concepts in pedodontics.


The dissimilation of glucose and gluconate by Acetobacter xylinum. 1. The origin and the fate of triose phosphate.


Training the child dental patient.

Training the child dental patient.


Roentgenological manifestations of systematic diseases in children.


The use of gold foil in dentistry for children.


This is how to do it.

This is how to do it.


Conservative dentistry gold in young permanent teeth.


The physician and postmyocardial infarction invalidism.


Idiopathic hypoventilation.

Idiopathic hypoventilation.


Dentistry and the under fives.

Dentistry and the under fives.


Premedicating pedodontic patients.

Premedicating pedodontic patients.


Mucopolysaccharides in kidneys of vertebrates of various classes.


Differentiation of leukocytic fibrinolytic enzymes from plasmin by the use of plasmatic proteolytic inhibitors.


Some observations on the value of the electrocardiogram in patients with chronic cor pulmonale.


Hematoma of the rectus abdominis muscle complicating anticoagulant therapy.


Interdisciplinary classification for the aged.


Alterations in fibrinogen, plasminogen, and inhibitors of plasmin with the growth of V2 carcinoma in rabbits.


Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides.


Effects of heparin, plasmin, dextran, and low molecular dextran on bioelectrically induced thromboses.


Removal of subarachnoid blood by the irrigation method.


Collagen turnover and reorganization in secondary wounds.


Liver dysfunction during protracted hepatic artery infusion of massive doses of fluorinated pyrimidine.


The noble gas ion laser as a light-knife.


A new phage type of Staphylococcus aureus associated with an outbreak of pemphigoid.


Intracutaneous injection of sebum and comedones. Histological observations.


Fixed drug eruption (phenacetin).

Fixed drug eruption (phenacetin).


Down's syndrome and chronic myelogenous leukemia.


Two interconvertible forms of yeast phosphofructokinase with different sensitivity to endproduct inhibition.


Role of inorganic phosphate in stimulating the glucose utilization of human red blood cells.


Erythema multiforme-like eruption due to sulfa.


Speaking fundamental frequency (SFF) characteristics of mongoloid girls.


Studies on digitalis. XI. Effects of digitoxin on the development of cardiac hypertrophy in the rat subjected to aortic constriction.


The release of bound adenosine triphosphatase from isolated bacterial membranes and the properties of the solubilized enzyme.


The metabolism of steroids by tissue from normal and neoplastic rat breast.


Interrelationship of human plasma kallikrein and plasmin in inflammation.


Effect of hydrocortisone on UDPG-dehydrogenase.


Frog gastric mucosal ATPase.

Frog gastric mucosal ATPase.


Kinetics of (Na+ + K+)-stimulated ATPase of rabbit kidney microsomes.


Urinary excretion of testosterone in idiopathic hirsuitism.


Structure and properties of the acetone adducts of 1-n-propyl nicotinamide iodide.


Titration of mitochondrial adenosinetriphosphatase with desaspidin.


Mercury Resistance of Staphylococcus aureus.


Education for the exceptional child.

Education for the exceptional child.


Skin problems in the school-age child.

Skin problems in the school-age child.


Acid mucopolysaccharides in rat skin. An electrophoretic study of dermal and subcutaneous tissue.


Studies on the isolation and composition of interstitial fluid in swine dentine.


A study of rose bengal and sulfhydryl reagents on stromal fragments of rabbit and human erythrocytes.


Valedictory address.

Valedictory address.


Haemorrhagic fever in children in Penang.


Types of C. diphtheriae in Kuala Lumpur.


Leucocyte alkaline phosphatase, leucocyte count and haemoglobin level in malayan new-borns and young infants.


Steady state analysis of BSP distribution between liver and plasma following single injection in intact dogs.


The prepuerin test in pregnancy: report of a trial.


Evaluation of intra uterine contraceptive devices.


Surgical induction of labour in modern obstetrics.


Seminal stains--identification and grouping.


A note of caution on the use of crystalline bovine albumin as a reference standard in the estimation of serum proteins.


The importance of ante-natal ABO-Rh-antibody determination.


Patella cubiti.

Patella cubiti.


Granulomatous peritonitis due to Ascaris eggs.


Maduromycosis of the forearm in a Bajau native of Sabah.


Chromoblastomycosis of the arm in a Chinese in Sabah.


A brief review of the diabetes mellitus, heart disease and blood pressure studies.


Vitamin C deficiency and connective tissue. 3. Determinations of hexosamine, uronic acid, hydroxyproline and uptake of radiosulfate (35S) in granulation tissue.


The natural history of ventricular septal defects in infancy.


The natural history of pulmonary valvular stenosis. Serial cardiac catheterizations in 21 children.


Annulo-aortic ectasia with cystic medial necrosis. Diagnosis and surgical treatment.


Association of pulmonary valvular stenosis and  muscular ventricular septal defect. Report of a case in a patient aged 75 years.


Phosphofructokinase activity of blood cells in leukemia.


Federal employment of the mentally and emotionally restored.


Farmer's lung, a new industrial disease.


Industrial problems relating to the stratum corneum.


The action of thiol inhibitors on the interaction of F-actin and heavy meromyosin.


Alkaptonuria, ochronosis, and low-back pain. A case report.


The pathology of laser irradiation of the skin and body wall of the mouse.


Effects of denervation on normal and dystrophic muscle: DNA and nucleotide enzymes.


Effect of right ventricular hypertrophy on infundibular pressure gradients in dogs.


Activation of thrombolysis by streptokinase in the cat.


Care of staff's back.

Care of staff's back.


The localization of adenosine triphosphatases in morphologically characterized subcellular fractions of guinea-pig brain. 1. The distribution of adenosine triphosphatase was studied in morphologically characterized subcellular fractions of guinea-pig brain. The conditions of homogenization were selected so as to favour the survival of nerve endings as organized structures. 2. A fraction consisting mainly of the external membranes of nerve endings was rich in a ouabain-sensitive Na(+)-K(+)-stimulated adenosine triphosphatase which closely resembled that present in the classical microsomal fraction studied by other workers, but which showed a higher specific activity. 3. A dinitrophenol-stimulated adenosine triphosphatase was located in the nerve-ending mitochondria. 4. The synaptic-vesicle fraction contained a small amount of adenosine triphosphatase that differed in its response to several ions and other compounds from the membrane, myelin and mitochondrial fractions, indicating freedom from contamination by these elements.


Neuromuscular transmission in vivo and the actions of decamethonium: a micro-electrode study.


Constituents of a microsomal fraction from the mammalian brain: their solubilization, especially by detergents.


Determination of oxo steroids as coloured salts of their Girard derivatives.


Staphylococcus bacteriophage patterns.

Staphylococcus bacteriophage patterns.


Antibodies against the various types of skeletal muscle fibres.


Intractable cardiac failure.

Intractable cardiac failure.


Quantitative study of sensitive and lysogenic bacteria surviving infection of a Staphylococcus by a temperate bacteriophage.


Corneal dystrophies associated with abnormalities of mucopolysaccharide metabolism.


Methods of detecting cancer antigens and antitumor antibody.


Study of the provision of dental care for handicapped children.


Use of antimetabolites in the study of normal and abnormal cell structure and function.


The effects of dental treatment on behavior of handicapped patients.


Oxidative phosphorylation. Biochemical effects and properties of trialkyltins.


Ethnocentrism and attitudes toward the physically disabled.


Human position sense and sense of effort.


Inhibition of citrate metabolism by sodium fluoroacetate in the perfused rat heart and the effect on phosphofructokinase activity and glucose utilization.


Vectorial aspects of adenosine-triphosphatase activity in erythrocyte membranes.


Studies in immunochemistry. 23. Some observations on the heterogeneity of preparations of human blood-group-specific substances.


Structural and enzymic aspects of the hydrolysis of adenosine triphosphate by membranes of kidney cortex and erythrocytes.


Cytochemical evaluation of metabolic inhibitors in cell culture.


ATP level and cleavage of sea urchin eggs Strongylocentrotus dröbachiensis (O. F. Müller).


Rate determining step of the coupled reaction system composed of H-meromyosin-adenosinetriphosphatase and creatine kinase.


The introduction and use of eastern drugs in the early middle ages.


Regulation of glucose uptake by muscle. 7. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, on the concentrations of hexose phosphates, nucleotides and inorganic phosphate in perfused rat heart.


Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles.


Chronic disease and employability: the physician's role.


Alcoholism in industry.

Alcoholism in industry.


Scadan lotion--a new preparation in the treatment of seborrhea.


Epidemiologic data on diseases of female workers in Yugoslavia.


Careers.

Careers.


Occupational medicine--the modern view.

Occupational medicine--the modern view.


The pre-steady state of the myosin-adenosine triphosphate system. II. Initial rapid absorption and liberation of hydrogen ion followed by a stopped-flow method.


The pre-steady state of the myosin-adenosine triphosphate system. I. Initial rapid liberation of inorganic phosphate.


The pre-steady state of the myosin-adenosine triphosphate system. 3. Properties of the intermediate.


Effect of thermal treatment on the calcium sensitivity of myosin B at low ionic strength.


ATP-induced contraction of sarcomeres.

ATP-induced contraction of sarcomeres.


Acute liver injury in ducklings as a result of aflatoxin poisoning.


Vitamin C deficiency and connective tissue. II. Determinations of hexosamine, uronic acid and hydroxyproline in guinea pig carcasses.


Fibrinolytic activity of blood in rheumatic fever.


Today's dentistry for today's children.

Today's dentistry for today's children.


The isolation and properties of epithelial-cell "ghosts" from rat small intestine. 1. The preparation of gram quantities of isolated epithelial-cell ;ghosts' from mucosal scrapings of rat small intestine is described. The method involves dispersing the tissue by gentle homogenization in 6% dextran in Krebs-Ringer phosphate, pH7.4, followed by filtration through nylon cloth and sedimentation by low-speed centrifuging. 2. The isolated epithelial-cell ;ghosts' contained all of the DNA, but only 52% of the protein and 53-57% of the RNA of the original homogenate. They contained most of the activity of the following enzymes found in the homogenate: aminopeptidase (71%); alkaline beta-glycerophosphatase (82%); invertase (92%); adenosine triphosphatase (93-116%); acid beta-glycerophosphatase (83%); nonspecific esterase (76%); succinate dehydrogenase (96%). Only small proportions of the total lactate-dehydrogenase (10%) and phosphoglucose-isomerase (2%) activities found in the homogenate were recovered in the isolated cell ;ghosts'. 3. The epithelial-cell ;ghost' preparation did not respire unless cofactors and substrates were added, and did not consume glucose or produce lactic acid from glucose. 4. The effect of varying the composition of the homogenization medium was studied. Concentrations of dextran (mol.wt. 15x10(4)) from 1 to 12%, solutions of dextrans (all at 6%) with mol.wt. varying between 3.6x10(4) and 2x10(6), and a solution of 8% polyethylene glycol (mol.wt. 4000) served equally well for the production of epithelial-cell ;ghosts'. Two of these solutions, however, 12% dextran (mol.wt.15x10(4)) and 6% dextran (mol.wt. 2x10(6)), were too viscous to allow the complete sedimentation of the cell ;ghosts' at low relative centrifugal forces. Omission of either Krebs-Ringer phosphate or dextran from the medium resulted in almost complete cell breakage during the homogenization. 5. The isolated cell ;ghosts' were used as a starting material for subcellular fractionation of rat intestinal mucosa by differential centrifugation. The distributions of protein and succinate-dehydrogenase activity among the fractions were compared with corresponding values in fractions isolated by differential centrifugation of mucosa homogenized in 0.3m-sucrose-5mm-EDTA, pH7.4. The method in which cell ;ghosts' were used as starting material gave a better separation and cleaner fractions than the method in which untreated mucosal scrapings were used.


Incidence of dental anomalies encountered in pedodontics.


Observations on the inhibition of preparations of porcine plasmin by serum and by urinary trypsin inhibitor (mingin).


Idiopathic prepuberal hypertrophy of the male breast. Histochemical evaluation and relation to gynecomastia and other disorders of the breast.


Effects of freezing on the stability of staphylococcal phages.


A study of uterine actn.

A study of uterine actn.


Intestinal transport of glucose in the silkworm, Bombyx mori L.


Effects of metals & reducing agents on the incorporation of amino acids into lens RNA & protein.


Studies in human malignant tissue. I. Protein synthesis in malignant & normal cervix uteri.


Lysophosphatidyl ethanolamine of certain species of mycobacteria.


Carbohydrate metabolism in experimental tuberculosis:  hepatic enzymes related to glycogen metabolism & synthesis of glycogen from labelled glucose.


Pigments of unclassified mycobacteria. I. Nature of pigments in a scotochromogenic strain (P-15) of mycobacteria.


Chromatography of plant lytic enzymes on carboxymethyl cellulose.


Some observations on the properdin system. VI. Preparation and properties of buffalo serum properdin.


N and C-terminal amino acids of collagen and its examination for the blocking of terminal amino groups by hexoses.


Aconitate isomerase in sugar cane.

Aconitate isomerase in sugar cane.


Protein bound hexosamine and hexoses in blood of normal adults and children, and pulmonary tuberculosis patients.


Occurrence of acid-soluble and acid-insoluble polyphosphates in rabbit liver.


Action of tetanus toxin on brain and liver mitochondria of resistant and susceptible animals.


Microbiological transformations of terpenes. V. Origin of 2-nonene, 2,3-dicarboxylic acid anhydride in the fermentation of terpenoid hydrocarbons by Aspergillus niger.


Metabolic activity of starch granules from the tapioca plant. II. Functional activity of starch granules from tuber.


Effect of some chemical modifications on the biological activity of catalase.


Effect of protein depletion on ribonucleic acid metabolism in rat liver.


Role of vitamin A in sulphate metabolism. I. Studies on sulphate incorporation into mucopolysaccharides in vitamin A deficient rats.


Effect of insulin on the resynthesis of glycogen in cerebral cortical slices.


Vitamin B12 & 14C incorporation into cell proteins of Escherichia coli 113-3. I. Incorporation studies with resting cells.


Spontaneous rupture of the rectus abdominis muscle.


Fractionation of mycoplasma cells for enzyme localization.


Respiratory control by an adenosine triphosphatase involved in active transport in brain cortex.


The regulation of kidney respiration by sodium and potassium ions.


Identification of active phosphoprotein in a cation-activated adenosine triphosphatase.


Urocanic acid in keratinizing tissue.

Urocanic acid in keratinizing tissue.


Characteristics of the ATP-ase activity of isolated neurons of rabbit.


A rapid pH-stat assay for phosphofructokinase and the forward reaction of phosphoglucose isomerase.


Adenosine triphosphatase activity in the rod outer segments of the pig retina.


Catalysis in reactions of 1-benzyl-1,4-dihydronicotinamide.


Enzymatic sulfation of steroids by bovine tissues.


Purification, crystallization and properties of activated sheep heart phosphofructokinase.


Highly specific sodium-potassium-activated adenosine triphosphatase from various tissues of rabbit.


Taming the monster in the chair.

Taming the monster in the chair.


Some acyl phosphate-like properties of P32-labeled sodium-potassium-activated adenosine triphosphatase.


The localization of myofibrillar ATPase activity in the flight muscles of the blowfly, Calliphora erythrocephala. The distribution of ATPase activity in the asynchronous flight muscles of Calliphora erythrocephala (Diptera) was studied at a fine structural level, using preparations of teased fibers, both unfixed and after brief fixation in hydroxyadipaldehyde, incubated in a medium for the histochemical demonstration of myosin or actomyosin ATPase. In relaxed fibrils, activity was found confined to the A bands and was absent from the H zones as well as from the Z and I band regions. At high magnification, deposits of final product, lead phosphate, appeared primarily related to the thick filaments, or to short lateral extensions from them. Evidence was gathered which indicated that this enzyme activity was that of a triphosphatase which did not act on dinucleoside or non-nucleoside substrates.


The effect of UV-radiation on HeLa cells infected with adenovirus.


Familiarity, dogmatism, and reported student attitudes toward the disabled.


Sodium, potassium-requiring adenosinetriphosphatase activity. II. Mechanism of inhibition by sulphydryl reagents.


On the presence of mucopolysaccharide material in the labyrinthine epithelium of chick embryo in the first moments of morphogenesis.


Steroid metabolism in the syndrome of testicular feminization.


Feminizing adrenal tumor in a six-year-old boy.


Southeast Asian Haemaphysalis ticks (Ixodoidea, Ixodidae). H. bandicota sp. n. from bandicoot rats in Taiwan, Thailand, and Burma.


The effects of fibrinolysin upon tendon healing in the dog.


Clinical studies on the cardiac performance by means of transseptal left heart catheterization. II. Left ventricular function in high output heart diseases, especially in hyperthyroidism.


The effect of oral potassium chloride on the normal and abnormal electrocardiogram; studies on the ventricular gradient II.


Nucleic acid metabolism in experimentally hypertrophied myocardium.


Blood pressure elevation and renal pathology in rats fed simulated Japanese diets.


Vitamin B6 depletion in man: urinary excretion of quinolinic acid and niacin metabolites.


The enzymatic degradation of heparin and heparitin sulfate. I. The fractionation of a crude heparinase from flavobacteria.


Characterization of the molecular region containing the active sites of myosin.


Partial resolution of the enzymes catalyzing oxidative phosphorylation. V. Properties of coupling factor 4.


Formation of a reactive myosin-phosphate complex as a key reaction in muscle contraction.


Carbon monoxide poisoning.

Carbon monoxide poisoning.


The pattern of innervation of the extrinsic ocular muscles and the intra-orbital ganglia of the albino mouse.


Anxiety--reappraisal of a concept.

Anxiety--reappraisal of a concept.


Breech presentation in the primigravida.


Diagnosis of Cushing's syndrome.

Diagnosis of Cushing's syndrome.


Available services in nutrition and dietetics.


Electrocardiogram of the month.

Electrocardiogram of the month.


Multiple repeat caesarean section.

Multiple repeat caesarean section.


Clinical pathologic conference.

Clinical pathologic conference.


Early atherosclerosis in the pig: a histological and histochemical study.


Fibrinolysin (human) in large therapeutic doses; its effect on hemostasis in wound-healing in dogs.


Back pain: the problems of diagnosis.

Back pain: the problems of diagnosis.


Human dermal fibroblasts in monolayer tissue culture. Effect of ascorbic acid analogues.


Factors influencing the utilization of ketone bodies by mouse adipose tissue. Factors influencing the utilization of ketone bodies by mouse adipose tissue in vitro were studied. Epididymal fat pads can oxidize DL-Beta-hydroxybutyrate-3-(14)C and acetoacetate-3-(14)C to (14)CO(2) as well as convert these compounds to fatty acid-(14)C. An increased output of (14)CO(2) from Beta-hydroxybutyrate-3-(14)C was noted in response to glucose plus insulin, succinate, oxaloacetate, L-asparate, and L-malate. Fatty acid synthesis from Beta-hydroxybutyrate was enhanced by glucose plus insulin, L-aspartate, L-malate, oxaloacetate, and citrate. Nicotinamide stimulated the oxidation of Beta-hydroxybutyrate but not of acetoacetate to CO(2), and did not affect fatty acid synthesis from either ketone body. Nicotinamide increased NAD(+) and NADP(+) levels in epididymal fat pads without affecting the concentration of NADH and NADPH. "Superlipogenesis" caused by fasting the mice for 48 hr and re-feeding them for 24 hr sharply enhanced CO(2) output and lipogenesis from Beta-hydroxybutyrate. The activities of glucose-6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, NADP-malic dehydrogenase, and citrate cleavage enzyme from mouse adipose tissue were increased during "superlipogenesis." Free fatty acid release by epididymal fat pads in vitro was slightly increased by Beta-hydroxybutyrate. The relationship of ketone body metabolism and lipogenesis in adipose tissue is discussed.


A comparative study of the influence of chlorpromazine and imipramine on mitochondrial activity. DNP- and Mg2+-activated ATPase, succinate dehydrogenase and aspartate transaminase.


The possibility of predicting the response of patients with early breast cancer to subsequent endocrine ablation.


Effect of fluoropyrimidines on delayed cutaneous hypersensitivity.


Formation in vitro of dehydroepiandrosterone conjugates in blood.


Interrelation between human chorionic gonadotrophin inhibitory activity in plasma and urine and the rate of urinary gonadotrophin excretion.


Monoamine oxidase activity of blood platelets and their ability to store 5-hydroxytryptamine in some mental deficiencies.


The spine as an indicator.

The spine as an indicator.


Chromosomes in two cases with acute childhood leukemia.


The phosvitin kinase enzyme of cerebral microsomes.


Inhibition of the sodium-ion-stimulated adenosine triphosphatase after treatment of isolated guinea pig cerebral cortex with ouabain and other agents.


Sugar consumption in vitro of the muscle tissue of diabetic patients.


Sodium-potassium activated ATPase from spinal cord of normal and injured rats.


Congenital aplasia of the myocardium of the right ventricle (Uhl's anomaly).


Clinical application of antidepressant agents in disabled and rehabilitation patients.


Fibrinolytic activity in thrombosed veins.


Inhibition of the biosynthesis of sulphurated mucopolysaccharides in metaphyseal cartilage of newborn pigs.


Recombination in bacteriophage T4: a mechanism. Genetic recombination between rIl mutants of T4 bacteriophage grown in Escherichia coli can occur under conditions where DNA synthesis is strongly inhibited by 5-fluorodeoxyuridine. The small amount of DNA synthesized under these conditions cannot account for the observed frequency of recombinants. The major mechanism of recombination in this system is a process of breakage and rejoining.


Influence of thiol-inhibiting substances on the effects of ethyl methane sulphonate (EMS) on chromosomes.


Histochemical study on localization of adenosine triphosphatase and 5-nucleotidase in the olfactory bulb of the rat.


Oral lesions of erythema multiforme. Histologic and histochemical observations.


Demodex folliculorum and rosacea. A clinical and histological study.


An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.


Anomalous origin of the left coronary artery from the pulmonary artery.


Congenital aortic stenosis due to failure of histogenesis of the aortic valve (myxoid dysplasia).


Syndrome of incomplete regional achondroplasia (ilium and ribs) with abdominal muscle dysplasia.


The aromatization of 10-methyl and 10-hydroxymethyl steroids by human placental microsomes.


Comparative anticoagulant effects of coumadin, heparin, and fibrinolysin on direct-current thrombosis of rat mesoappendix vessels.


The frequency of aganglionosis associated with imperforate anus.


Control of the carriage of epidemic phage type staphylococci and recurrent sepsis by biological means.


Dermatoglyphics in translocation Down's syndrome.


Studies of male survivors of myocardial infarction. VI. The electrocardiogram. Electrocardiograms of 101 men who survived myocardial infarction for at least three months and were free of hypertension, heart failure and other significant disease were analyzed. Within the range of 30 to 70 years, age had no apparent influence on the ECG. Six ECGs were borderline, 79 were abnormal and 16 had returned to normal. Of those with the pattern of infarction, 56 were transmural and 22 nontransmural. For all cases, posterior involvement was somewhat more common than anterior (46 to 32), but it was less common in non-transmural infarction. Ventricular premature beats, always unifocal and few in number, were the only abnormality in rhythm. Atrial fibrillation was conspicuously absent. There were four instances of complete left bundle-branch block. No evidence of left ventricular hypertrophy was seen. The clinical significance of these observations is briefly discussed.


The concept of susceptibility to hearing loss.


Medical aspects of invalidity retirement programs in Europe. II.


Compensation for injuries while commuting to and from work.


Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 4. Regression of deciduomata.


Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 3. Formation of deciduomata.


The acid mucopolysaccharides. These essential components of living tissue exhibit demonstrable alterations of diagnostic assistance in certain diseases.


Chromosomal aberrations in acute leukemia.


Comparative biochemistry of keratosulfates.


Mechanism of formation of bovine plasminogen activator from human plasmin.


Adenosine triphosphatase activity of yeast hexokinase and its relation to the mechanism of the hexokinase reaction.


Studies on the secretion and interconversion of the androgens. II. Methods for estimation of rates  of secretion and of metabolism from specific activities of urinary metabolites.


Studies on the secretion and interconversion of the androgens. 3. Results obtained after the injection of several radioactive C-19 steroids, singly or as mixtures.


Physically crippled, but emotionally secure.


Plasma testosterone and estrogen levels, urine testosterone excretion, and sebum production in males with acne vulgaris.


Re-employment or retirement. Background and definitive statement of the problem of disability.


Oral enzyme therapy in treatment of acne: a preliminary report.


Scleredema.

Scleredema.


Lysis of arterial clots. Using fibrinolysin in an isolation perfusion system.


The cardiac pathology of chronic exogenous obesity.


Prolonged bed rest in the treatment of the dilated heart.


The identification of successful teachers of mentally or physically handicapped children.


Effect of irradiation on vascular permeability and on blood mucopolysaccharide and serotonin levels.


Changes in heart muscle and liver proteins in experimental myocardial infarction.


Benzene and dioxane electric moments of N-alkyl-substituted nicotinamides from measurements in mixed benzene--dioxane solutions.


Thyroid function in mongoloid children. Thyroxine-binding capacity.


Management of femoral artery obstruction. Complications of femoral venipuncture.


The management of tube pedicles.

The management of tube pedicles.


The effects of temperature on the isolated muscle spindle.


A bath that folds--from Sweden. To facilitate bathing of very ill or disabled patients.


Motor fibres innervating extrafusal and intrafusal muscle fibres in the cat.


Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Mavilla, Vega Alta, Puerto Rico.


Regulatory mechanisms in carbohydrate metabolism. VII. Hexokinase and phosphofructokinase.


Regulatory mechanisms in carbohydrate metabolism. 8. The regulatory function of phosphate in glycolysis.


Partial resolution of the enzymes catalyzing oxidative phosphorylation. VI. Studies on the mechanism of cold inactivation of mitochondrial adenosine triphosphatase.


Dio-9, an inhibitor of coupled electron transport and phosphorylation in chloroplasts.


In right good company.

In right good company.


Pediatric conditions related to diseases and functions of the placenta.


Birth trends in Nebraska.

Birth trends in Nebraska.


Neurologic manifestations of dysbarism (decompression sickness).


Etiology of carcinoma: genetic determinism.


The acute abdomen complicating pregnancy.


XII. The disabled patient at home.

XII. The disabled patient at home.


Subcutaneous rupture of the rectus abdominus muscle with incarcerated hernia and bowel obstruction.


Reflex discharges in phrenic and abdominal muscle nerves to vagal afferent nerve stimulation.


Low backache.

Low backache.


Differentiation of the skeletal muscle in the chicken. 8. ATPase activity during development.


Platelet agglutination and deagglutination with a sulfhydryl inhibitor, methyl mercuric nitrate: relationships to platelet ATPase.


Nuclear lobe count and incidence of drumsticks in Indian children with Down's syndrome.


Testicular feminization.

Testicular feminization.


Familial male hermaphroditism with delayed and partial masculinization.


Mongolism in newborn infants. An examination of the criteria for recognition and some speculations on the pathogenic activity of the chromosomal abnormality.


An autopsy case of Sézary's reticulosis.


Studies on acid mucopolysaccharides of pig gastric mucin. I.


Biochemical differentiation of trisomic Down's syndrome (mongolism) from that due to translocation.


The orthopedic aspects of low back pain.


Occupational dermatitis.

Occupational dermatitis.


Diagnosis of industrial dermatitis.

Diagnosis of industrial dermatitis.


Handicapped children. The problem and a plan for their rehabilitation.


Current occupational health in Latin America.


Compensation for injuries in fighting.

Compensation for injuries in fighting.


Remediation of learning disabilities in a public school system.


Body image of crippled children as seen in draw-a-person test behavior.


Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. I. Framework: oestrous cycle and pseudopregnancy.


Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. II. Induction.


Acute anemia and abdominal tumor due to hemorrhage in rectus abdominis sheath following anticoagulant therapy.


Chromosome studies on a radiographer and her family. Report of one case of leukemia and two cases of Down's syndrome.


A simple test for inactivation of an enzyme during assay.


Effect of the antimetabolite, 6-aminonicotinamide, on sound-induced seizures in mice.


Vocational rehabilitation service in a general hospital.


The effect of nucleic acid antagonists on cell division and oral organelle development in Tetrahymena pyriformis.


Beryllium disease. Report of the section of nature and prevalence committee on occupational diseases of the chest--American College of Chest Physicians.


Demonstration of 3-beta-hydroxysteroid dehydrogenase in the testis of Tilapia mossambica (Cichlidae, Teleostei).


Intramuscular pressure changes during contraction in relation to muscle spindles.


Effects of heparin, plasmin, dextran and low-molecular-weight dextran on electrically induced thromboses.


The challenge of research in oral pediatrics.


The effect of oligomycin on the respiration of tissue slices.


The effect of long-chain fatty acids on orthophosphate-adenosine 5'-triphosphate exchange activity associated with oxidative phosphorylation.


The role of CA2+ in the adenosine triphosphatase activity of myofibrils.


A method for the demonstration of sulphated mucopolysaccharides in tissue sections.


Cutaneous focal mucinosis. A clinicopathological and histochemical study.


Scleromyxedema. A variant of Lichen myxedematosus.


Tetracycline sun sensitivity.

Tetracycline sun sensitivity.


Oral tetracycline treatment on bacterial flora in acne vulgaris.


The uses and limitations of hypnosis in children's dentistry.


The child, the parent and the dentist.

The child, the parent and the dentist.


How many disabled?

How many disabled?


Activity patterns of purified ATPase from Arachis hypogaea.


Legal implications of the battered child syndrome.


Wilful abuse of children.

Wilful abuse of children.


Response of malignancy to phenylalanine restriction. A preliminary report on a new concept of managing malignant disease.


"Nonparticipation" and the Sherman Act.

"Nonparticipation" and the Sherman Act.


"The role of Blue Shield in the medicare program".


A rapid method for the assay of small quantities of sulfomucopolysaccharides.


The variation of adenosine triphosphate and adenosine triphosphatase in Tribolium confusum, Duval at the different stages of its life cycle.


An address given at the dedication of the Davis Woolf Goldstein Library.


Olfactory groove meningioma: herniation following spinal anesthesia.


Disaccharide intolerance.

Disaccharide intolerance.


Leukoplakia of the vulva.

Leukoplakia of the vulva.


The humoral regulation of erythropoiesis.


Typhoid fever.

Typhoid fever.


The role of lysosomes in hypersensitivity reactions: tissue damage by polymorphonuclear neutrophil lysosomes.


Immunization in virus disease.

Immunization in virus disease.


Targets of population in Singapore.

Targets of population in Singapore.


Factors affecting prognosis of choriocarcioma.


A plea against abdominal hysterotomy in the treatment of hydatidiform mole.


Behaviour therapy.

Behaviour therapy.


A malaria parasite, plasmodium (Vinckeia) booliati sp.nov., from a Malayan giant flying squirrel.


Pudendal block anaesthesia. A new technique in regional anaesthesia with special reference to forceps delivery.


Aflatoxins in unrefined groundnut oil.

Aflatoxins in unrefined groundnut oil.


The oxygen consumption of Plasmodium berghei in the presence of normal rat serum, immune rat serum and chloroquine sulfate.


Systematic and distributional studies of helminths of Malayan mammals.


Studies on the cytology and histology of helminths.


The lymphatic system of a species of amphistome.


Morphological, histological and cytological studies on the nervous system of Ceylonocotyle sp. (Paramphistomata).


The life-history of Echinostoma ilocanum.


Multiple infections of larval trematodes in one snail.


The life cycle of two brachylaimid flukes in Malaysia.


Fascioliasis in cattle near Kuala Lumpur.


A single abnormal proglottid Taenia saginata.


The size of microfilariae in relation to the storage time of unfixed and fixed thick blood films.


Intraocular parasitism.

Intraocular parasitism.


Correlation of habitat to rodent susceptibility with Angiostrongylus cantonensis (Nematoda: Metastrongylidae).


Studies on Hepatojarakus malayae Yeh, 1955 (Trichostrongylidae: Nematoda).


Observations on the presence of immunity in rats to Angiostrongylus cantonensis (Chen).


The American cockroach, Periplanta americana, as an intermediate host of the pentastomid, Raillietiella hemidactyli.


Laboratory observations on the comparative feeding preferences by Aedes schuellaris malayensis from Kuantan and Singapore.


Anopheles maculatus, a new vector of Wuchereria bancrofti in Malaysia (Pulau Aur) and a potential vector on mainland Malaya.


Anopheles philippinensis, a new host record of Coelomomyces sp. in Perlis.


A tracheal mite from Valanga nigricornis Burm. (Orthoptera: Acrididae).


Anopheles balabacensis balabacensis identified as a vector of monkey malaria in malaya.


The unusual life-history of Vatacarus ipoides Southcott (Acarina, Trombiculidae).


Laboratory diagnosis of trachoma.

Laboratory diagnosis of trachoma.


Laboratory diagnosis of haemorrhagic fever.


Rapid typing of dengue viruses by the microprecipitin agar gel diffusion technique.


Mycotic Keratitis.

Mycotic Keratitis.


Coagulation of Malays and caucasians: a comparative study of two groups of young soldiers.


Freeze-dried smallpox vaccine; report of a trial in Kuala Lumpur.


A familial minute isochromosome.

A familial minute isochromosome.


Autoimmunity and chromosomal aberrations.


The bacteriology of tropical pyomyositis in Uganda.


Rhabdomyosarcoma.

Rhabdomyosarcoma.


Tuberculosis: is it compensable or not?

Tuberculosis: is it compensable or not?


More help in the home for the handicapped.


The relaxing incision in the anterior rectus sheath in the operative treatment of inguinal hernia.


The sulfated mucopolysaccharides from human umbilical cord.


The genetic mucopolysaccharidoses.

The genetic mucopolysaccharidoses.


A state department-university approach in providing internship experiences for prospective leadership personnel in special education.


Psychological needs and preferences for teaching exceptional children.


Effectiveness of an academically oriented teaching program with crippled children.


The origin of spontaneous contractions and changes in neuromuscular transmission in barium-treated muscle.


Experimental collagen-like disease induced by repeated injections of papain, with evidence of autoimmune antibodies.


Exchange of cerebrospinal fluid potassium with blood and brain. Study in normal and Ouabain perfused cats.


Effect of quinones on mitochondrial phosphorylation, Pi-ATP exchange, and ATPase activities. II. Vitamin K-2 homologues and K-1 derivatives.


Increased brain radiocopper uptake in Wilson's disease.


The handicapped child and the law.

The handicapped child and the law.


Thrombelastographic patterns produced by fibrinolytic agents incorporated in fibrin.


Fusimotor function during sleep in unrestrained cats. An account of the modulation of the mechanically and electrically evoked monosynaptic reflexes.


Gaps in the nation's services for children.


Alpha-rigidity in reserpinized rats.

Alpha-rigidity in reserpinized rats.


Pediatric dental rehabilitation.

Pediatric dental rehabilitation.


Behavioral patterns of the child patient.


A survey of pediatric dentistry in Cincinnati.


Age changes in content of sulfhydryl groups and adenosinetriphosphatase activity of myosin.


Effect of heavy water D2-O on resistance of plant and animal cells, cell models and proteins to certain denaturing factors.


The role of the public health nurse in the discharge of the handicapped child to the community.


Food and rehabilitation of the handicapped.


Urinary excretion of mucopolysaccharides in normal individuals and in the Marfan syndrome.


Analysis of mucopolysaccharides in partially aqueous media.


Optical rotatory dispersion of mucopolysaccharides and mucopolysaccharide-dye complexes.


A possible mechanism for the anti-inflammatory effects of proteolytic enzymes.


A case of idiopathic cavitation of lung demonstrated at the Postgraduate Medical School of London.


Selenium and rabbit skeletal muscle aldolase and myosin.


A dental service for children with bleeding disorders.


Studies in myocarditis. 3. On the frequency and nature of some common symptoms.


The "dimeric acid product" of 1-methyl-1,4-dihydronicotinamide.


The effect of ouabain on the hydration and the adenosine triphosphatase activity of the cornea.


Hereditary renal disease associated with  deafness; Alport's syndrome.


Two cases of atypical leukoencephalitis.


A contribution to the study of the body axis in mammals with special reference to domesticated dog.


The torsion of the roots in human lower molars.


Finger patterns and ridge counts of the Dogons.


The influence of plasma substitutes on the suspension stability of human blood.


Left ventricular enlargement and hypertrophy. A clinical and angiocardiographic study.


Mucopolysaccharides in sweat.

Mucopolysaccharides in sweat.


A gastroenteritis outbreak of Staphylococcus aureus, type 29.


Lymphoblast transformation in sulphonamide sensitivity.


The dental management of the physically handicapped child.


Fatal case of toxic erythema after chlorpropamide (Diabinese).


Studies on the biological activity of Rhus striata ("manzanillo"). I. Hemolytic activity.


The effect of ovarian hormones on the sulphomucopolysaccharides of the uterus.


On the histochemical nomenclature for sialomucins.


Back pain in a young man.

Back pain in a young man.


Development of activity of 3 beta-hydroxysteroid dehydrogenase in human fetal tissues and in two anencephalic newborns.


The pathogenesis of ocular lesions of infectious canine hepatitis. II. Experimental ocular hypersensitivity produced by the virus.


Metabolic processes in skin.

Metabolic processes in skin.


The effect of progesterone on the sebaceous glands of the rat.


Periodicity of S35 uptake in rat femurs.


Psychologic factors in backache.

Psychologic factors in backache.


Similar cytological effects of hydroxylamine and 5-FUDR, agents with different modes of action. An analysis of chromosome breakage.


Impetigo in the Waikato.

Impetigo in the Waikato.


Basophilic leucocytes and Hashimoto's thyroiditis. Skin reaction upon intradermal injection of thyroid extract studied by skin window technique.


New help for the severely retarded and emotionally disturbed child.


Essential hypertension. A twenty-year follow-up study.


Helpful diagnostic clues for differentiation of atopic dermatitis from seborrheic dermatitis.


Can pedodontics and orthodontics be combined in practice?


Pedodontic care for the deaf and blind.

Pedodontic care for the deaf and blind.


Diabetes screening with Dextrostix in an industrial plant.


New AMWA president--1966.

New AMWA president--1966.


The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods.


Studies on swelling-shrinkage and oxidative phosphorylation of liver mitochondria of rat fed on 3'-methyl-4-dimethylaminoazobenzene.


Biosynthesis of isovalthine.

Biosynthesis of isovalthine.


On the relation between the fatty acid composition and the swelling rate in rat liver mitochondria.


On the carbon origin of isovaleric acid residue of urinary isovalthine.


Growth of interorbital distance and skull thickness as observed in roentgenographic measurements.


Ultrastructure of nasal scleroma (emphasizing the fine structure of Klebsiella rhinoscleromatis within the lesion).


Exchangeable water, sodium and chloride in the skin of mice.


Mechanism of melanophore dispersion. II. Stimulus-reaction-recovery and receptor problem.


The effect of Sr2+ on swelling and ATP-linked contraction of mitochondria.


Endocrine effects on rat cardiac myofibrillar ATPase.


A study of back cases in an outpatient clinic.


Attempts to cultivate Mycobacterium lepraemurium in cell-free media.


Severe respiratory failure. The diagnosis and management of 37 cases.


Clinical relapse in early syphilis: unusual skin lesion following inadequate treatment.


A histochemical and electron microscopic study of skeletal muscle in a case of Pompe's disease (glycogenosis II).


Abdominal electromyography during micturition.


Heart size and prognosis in myocardial infarction.


Dietary production of myocardial fibrosis in the rat.


Clinical pathologic conference.

Clinical pathologic conference.


Disability under Social Security: total-temporary impairments now entitled to benefits.


Increase of serum beta-glucuronidase activity in human diabetes mellitus.


Intramyocardial lesions in patients dying suddenly and unexpectedly.


The handicapped child and the family.

The handicapped child and the family.


Thymidine incoporation into mammalian strain L-cells after the action of 5-fluorodoxyuridine and the effect of uracil.


Separation of adenosine triphosphatase of HK and LK sheep red cell membranes by density gradient centrifugation. Membrane fragments from high potassium (HK) and low potassium (LK) sheep red cells were separated by density gradient centrifugation. Three preparations were studied: (1) HK membranes sonicated for 20 minutes, (2) HK membranes sonicated for 3 minutes, and (3) LK membranes sonicated for 3 minutes. The adenosine triphosphatase (ATPase) activity in the maximally disrupted preparation (1) was not sensitive to Na + K and was recovered in relatively small but heavy (specific gravity 1.19) fragments which made up no more than 8 per cent of the total membrane. Both Na + K-sensitive (S) and Na + K-insensitive (I) ATPase activity were found in the more gently broken up preparations (2) and (3) but the ratio of S- to I-ATPase was much greater in HK than in LK membrane fragments. S-ATPase activity in preparation (2) was about 50 per cent that observed in HK membranes prior to sonication. S-ATPase activity was recovered from the density gradient in relatively large but light (specific gravity 1.10) fragments. As was the case with the maximally disrupted preparation (1), I-ATPase activity in both preparations (2) and (3) was recovered in small but heavy (specific gravity > 1.20) fragments. The possibility that sensitivity of sheep red cell membrane ATPase to Na + K depends on the association between units containing the enzyme(s) and large, light, phospholipid-containing components is discussed.


Let's dress the disabled for living.

Let's dress the disabled for living.


Mongoloids, twins and tolerance.

Mongoloids, twins and tolerance.


On the action of strophanthin G.

On the action of strophanthin G.


Influences of protamine on the na+, K+-dependent ATPase and on the active transport processes of potassium and of L-DOPA into brain slices.


Connection between membrane adenosine triphosphatase activity and potassium transport in erythrocyte ghosts.


Evaluation of the method of rivanol precipitation of [35S] sulphated mucopolysaccharides present in the material obtained from a small group of cells.


Connective and supporting tissues: mucopolysaccharides of connective tissues.


Chromosome abnormalities in a patient suffering from Huntington's chorea.


The care of the physically handicapped child.


The effect of digitalis on the renal tubular transport of glucose in normal and in heartless dogs.


Granulopoiesis in Down's syndrome.

Granulopoiesis in Down's syndrome.


A new radiographic finding in mongolism.


Antimitotic action of cornin as a biologically active polypeptide. II. Physiological effects of cornin on dividing cell.


Immunochemical analysis of antigenic properties of human stomach cancer.


Antimitotic action of cornin as a biologically active polypeptide. I. Biochemical properties of cornin.


A histotopochemical study of the parathyroid gland of the albino rat.


Acne: tetracyline or not?

Acne: tetracyline or not?


The enzymic activity of the outer shell of Lactobacillus arabinosus.


We're too fat.

We're too fat.


What should we tell the patient?

What should we tell the patient?


Brdicka serum filtrate reaction applied to normal and cancerous menstrual fluids.


Obesity and the emotions.

Obesity and the emotions.


Diaphragmatic hernia in a premature infant.


Neurologic manifestations accompanying burns (burn encephalopathy).


Individuality of intellectual development.


The impact of disability on the child.

The impact of disability on the child.


The abnormal child: his impact on the family.


Lack of correlation between natriuretic activity and inhibition of renal Nak-activated ATPase.


Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.


Study of employment of 222 men with spinal cord injury.


Golden anniversary--golden opportunity.

Golden anniversary--golden opportunity.


Psychomotor abilities of familial, brain-injured and mongoloid retarded children.


The chances of reducing the incidence of skin infections of the newborn in a maternity hospital.


Special clothing for the handicapped. Review of research and resources.


Comparative antibiotic sensitivity studies in pustular acne vulgaris, 1954 and 1962.


Problems of terminology in endocrinology.


Studies on the effect of hypophysectomy and of partial hepatectomy on the aminoacid incorporating system from rat liver.


Regulation of protein synthesis: an alternative to the repressor-operator hypothesis.


A radioautographic and radiometric analysis of the influence of parathyroid extract on the proline binding capacity of cultivated mouse radius rudiments.


Progressive brachycephalization: reproduction and headform in the Netherlands. A preliminary report.


Reflectometry of the skin in Dogons.

Reflectometry of the skin in Dogons.


"Doubling" of the palatal root in the second and third upper molars.


The deposition of radioactive Ba and Sr in the aortic wall.


Hemolymph protein and amino-acid composition as influenced by the corpus allatum in Locusta migratoria migratorioides (r. & f.).


Abdominal-wall hematomas.

Abdominal-wall hematomas.


Acid mucopolysaccharides in electron microscopy. The use of the colloidal iron method.


Phosphorus metabolism of intact crab nerve and its relation to the active transport of ions.


A comparison of the phosphorus metabolism of intact squid nerve with that of the isolated axoplasm and sheath.


S35 taurine metabolism in normal and mongoloid individuals.


Concentrations of uric acid in the sweat of control and mongoloid children.


Histochemical and histoenzymological studies on the growing cartilage in the Turner's syndrome.


Congenital malformations produced in chickens by fluorinated pyrimidines.


Massive neurofibrosarcoma of the anterior abdominal wall.


Notes from a visit to the Soviet Union: treatments and studies of alcoholism; education about alcohol; drinking in Georgia.


IUPAC-iub Commission on Biochemical Nomenclature. Tentative rules. Trivial names of miscellaneous compounds of importance in biochemistry.


Experimental tetracycline labeling in avian osteopetrosis. Osteopetrosis was experimentally produced and lesion development in time was studied by fluorescent illumination of tetracycline labels in the bone. Bones from birds 84, 115, 186 and 354 days of age were examined by ground section under ultraviolet light. Periosteal activity of the tibia and femur was present in normal bones at 84 days of age but had stopped at 115 days. Focal periosteal activity of osteopetrotic lesions was present at 186 days but not at 354 days of age. Slight endosteal activity of osteopetrotic bones was present at 354 days of age. Osteopetrotic bone formed at a rate of 1.26 mm. per week or 6 times faster than normal bone in some of these lesions. Tetracycline diffused throughout the 354-day-old osteopetrotic lesion but not normal compact bone indicating that the osteopetrotic bone is porous and spongy.


Amyloidosis in captive anseriformes.

Amyloidosis in captive anseriformes. During the period 1945-1962, percentage deaths of anserine birds (ducks, geese and swans) did not vary remarkably from year to year even though the population has more than quadrupled during the same period. The number of deaths with amyloidosis has increased significantly even though the death rate did not change. The number of deaths due to tuberculosis, mould, renal diseases, hepatitis and infection accompanied by amyloidosis also increased, especially during the second half the study period. Cases of known secondary amyloidosis accounted for 71.4% whereas 28.6% of the remaining cases were classified as "doubtfully" primary. Sites of deposition amyloid in the two categories were the same and it has never been observed in the heart. The amyloid deposits in the birds did not differ from those in man when examined by number of histochemical methods.


Surface temperatures of avian osteopetrotic bones. Body temperatures and surface temperatures of metatarsal bones were recorded in normal and osteopetrotic chickens. Osteopetrotic lesions were 6.5 F warmer than normal bones but there was no corresponding increase in body temperature at a given environmental temperature. This indicates that the temperature elevation in the osteopetrotic lesion is a local phenomenon and not a systemic response. This also supports earlier observations that osteopetrotic bones feel warmer to the touch than normal bones.


Production of antibodies in the mammary gland with especial reference to virus neutralizing antibody.


Volunteers blaze a trail.

Volunteers blaze a trail.


Down's syndrome with unusual karyotype and thyroid autoantibodies.


Enzyme activities and maximal rates of glycolysis in anaerobic myocardium.


A comparison of two antiseptic and steroid creams, illustrating the importance of an "order effect" in such trials.


Genetic interference and recombination in phage T4: the role of heterozygotes.


Study of mechanisms which preserve blood fluidity and the effect of their inhibition on thrombogenesis.


Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections.


The halt and the whole: thoughts on adaptation.


The use of metabolic inhibitors in studies on the mode of replication of vaccinia virus.


Combined oral, topical and surgical treatment of onychomycosis.


Improved griseofulvin therapy for tinea pedis.


The mechanism of calcium and magnesium uptake from sea water by a marine bacterium.


Backache in industry.

Backache in industry.


Civil actions for damages versus workmen's compensation benefits.


Management of atopic dermatitis.

Management of atopic dermatitis.


Office management of acne vulgaris.

Office management of acne vulgaris.


Hexosamine content of callus tissue.

Hexosamine content of callus tissue.


A multidisciplined evaluation clinic for the child with a handicap. A summary of the first year's activities.


Biochemical properties of anti-inflammatory drugs. VI. The effects of chloroquine (resochin), mepacrine (quinacrine) and some of their potential metabolites on cartilage metabolism and oxidative phosphorylation.


Biochemical study of anti-inflammatory and anti-arthritic properties of glycyrrhetic acid.


Molecular mechanisms of genetic recombination of bacteriophage. V. Two kinds of joining of parental DNA molecules.


A model illustrating some aspects of muscle spindle physiology.


Diagnosis and surgical correction of combined congenital defects of supra-umbilical abdominal wall, lower sternum, and diaphragm.


Studies on the adenosine triphosphatase, calcium uptake and relaxing activity of the microsomal granules from skeletal muscle.


Effect of different steroids on lactating rats.


An effect of growth hormone on hexose phosphate metabolism.


Identification of a cytopathogenic agent infectious for puppies as a canine herpesvirus.


Effect of diisopropyl fluorophosphate on gastric secretion and gastric ATPase.


Stimulation of erythrocyte glycolysis by nicotinamide adenylates.


In vitro inhibition of Na+-K+ and Mg2+ ATPases by mono, di and trivalent cations.


Eruption of teeth through the oral mucosa.


Immunological study of rabbit cysticercosis. I. The suitability of agar gel diffusion precipitation and indirect haemagglutination tests.


Correction of the von Krogh equation.

Correction of the von Krogh equation.


Studies on biochemical and metabolic changes of rat and guinea-pig skin following congelation.


Hormone assay studies in patients with anorexia nervosa.


Preparation--properties of A Na+ + K+-activated MgATPase in the rabbit auricle.


The protective influence of substances upon the antimitotic effect of epinephrine and its metabolites in human cell cultures.


Interactions of positive inotropic agents and metabolites on the rat ventricle strip.


Brow presentation.

Brow presentation.


Medical treatment of hypertension.

Medical treatment of hypertension.


Study of the UV-induction of mutations in bacteria.


Iatrogenic acute anemia: primaquine sensitivity.


Hepatitis.

Hepatitis.


Renal glycosuria.

Renal glycosuria.


A simulation study of mammalian phosphofructokinase.


The glycosaminoglycans of the early stage of fracture repair.


The glycosaminoglycans in a pseudarthrosis femoris.


Common nondiscogenic back disorders.

Common nondiscogenic back disorders.


What every doctor should know about workmen's compensation.


The radiological manifestations of the initial phases of rheumatic carditis in childhood.


Dental care for the special patient. (Handicapped--chronically ill--aged).


Diaphragm movements and the diagnosis of diaphragmatic paralysis.


The use of short-induction nitrous oxide and oxygen with penthrane; a new concept in pediatric oral surgical anesthesia.


An investigation by electron microscopy of the nucleoside phosphatase activity of amphibian and mammalian erythrocytes. Amphibian and mammalian blood was washed in isotonic saline, fixed in glutaraldehyde, and then stained in the ATPase medium of Wachstein and Meisel. The blood cells were subsequently postfixed in osmium tetroxide, embedded in epoxy resins, and studied by electron microscopy. The plasma membranes of amphibian erythrocytes, from the newt Triturus cristatus and the frog Rana esculenta, were stained after incubation in media containing ATP or ADP as substrates, but were unstained after incubation in media containing AMP or sodium beta-glycerophosphate. The addition of 0.001 M ouabain to ATP-containing media did not inhibit the staining of the plasma membranes, but the omission of Mg(++) ions from the medium inhibited staining. The plasma membranes of rat and rabbit erythrocytes were never stained after incubation in any of the media used.


Treatment of acne vulgaris with Secomat -S lotion.


Staphylococcal enterotoxin.

Staphylococcal enterotoxin.


Biological attributes of staphylococcal cell walls.


Observations of the staphylococcal nasal carrier state.


Patterns of transmission of staphylococci.


Intracellular phosphate release by the Na+-K+-activated membrane ATPase.


Reduction of dynamic sensitivity of primary muscle spindle endings in experimental tremor.


A method for turbidimetric measurement of heparin: its application to the estimation of heparin in aortic tissue.


Aortic acid mucopolysaccharides and collagen in scorbutic guinea pigs.


Increase in uric acid biosynthesis produced by 2-substituted thiadiazoles.


Separation and characterization of delta-5-3-hydroxy-C19-steroids by thin-layer chromatography.


Management of skin problems in the adolescent.


Chemical analysis and biological activities of fatty acids from the liver of x-ray irradiated rabbit, the antitumor agent so-called OX.


Mechanism of induction of anisocytosis.

Mechanism of induction of anisocytosis.


Cellular antibody in mice bearing Ehrlich cancer. I. A quantitative study on antitumor activity of cellular antibody in vitro.


Acid mucopolysaccharides in the oral epithelium.


Cytochemical studies of adenosine triphosphatase activity in the sarcoplasmic reticulum.


Factors influencing activation of phosphofructokinase.


Unbelievable medico-legal adjudications.


The influence of heating on the morphology and photochemical activity of isolated chloroplasts.


Preparation of rabbit muscle myosin or actomyosin free of 5'-adenylic acid deaminase.


The effect of lipids on enzyme levels in beating rat heart cells.


Left ventricular hypertrophy in chronic bronchitis.


The Graham-Steell murmur re-evaluated.

The Graham-Steell murmur re-evaluated.


Extracts from a lecture delivered by A. Withnell, Esq., B.Sc., M.D., D.P.H. to dental surgery assistants in the employment of the Staffordshire County Council School's Health Service.


Anomalies of the origin of coronary arteries. (Special reference to single coronary artery).


Hog cholera. V. Demonstration of the antigen in swine tissues by the fluorescent antibody technique. The fluorescent antibody technique was employed to detect hog cholera virus in tissue sections of various organs from experimentally infected swine. The method proved to be highly sensitive and infection could be detected in these animals as early as three days after inoculation with the virus. Best results were obtained when tissues were collected from young animals in advanced disease rather than from sows or from pigs in the early febrile phase. Tonsil, spleen and lymph node were the tissues of choice and were most satisfactory when removed from freshly killed animals rather than from those that had died.


Progressive myelopathy in a dog caused by thorium dioxide. A study of the use of Thorotrast as a contrast media in myelograms in dogs is presented, indicating that the material introduced into the cerebro-spinal fluid, will become permanently associated with the meninges, leading to the development of myelopathy.


The physiopathological changes in synovial fluid in arthritic swine. There was produced with Ery. rhusiopathiae a rheumatoid-like arthritis in swine, which passed successively through acute, sub-acute and chronic stages. This was typically a non-suppurative proliferative change with concurrent changes in the joint fluid. The arthritis was shown to persist even though the initial inciting agent could not be isolated from the advanced cases of chronic polyarthritis. This strongly suggests that the pathological process responsible for this arthritis can become autonomic and probably is related to a state of hypersensitivity. The cellular changes observed in the synovial fluid did not differ markedly from those of rheumatoid arthritis in man. Synovial fluid mucinous changes were apparent in the decreased viscosity observed grossly. Definite changes in the character of the precipitate produced by acetic acid treatment of the fluid were also observed.


Observations on a swine herd health program. Observations on a swine herd health program are reported. A primary purpose was to show that such programs could provide economic benefits to swine breeders and sources for breeding stock of minimum disease status. The possible influence of diseases of swine, including atrophic rhinitis and virus pneumonia, on both aspects are discussed. The inadequacy of knowledge of diseases of swine, both specifically and generally, is pointed out. Veterinary supervision of a swine herd will result in economic benefits to an average capable owner. There is both merit and need for such programs, but as to what health standards would be reasonable, practical, and meaningful, is still not clearly defined.


Abnormal bleeding conditions in urologic patients.


Brachial artery puncture: an oft neglected clinical tool in the evaluation of hypertension.


Gas gangrene infection: combined treatment including 3,432,000 international units of polyvalent gas gangrene antitoxin.


Carcinoma of the tongue: the role of chronic irritation.


Studies on reticuloendothelial system and hemaotpoiesis. I. Studies of extramedullary hematopoiesis.


The appearance of perinucleolar halos in cultured cells with 5-fluorouracil.


Neotetrazolium salt (NT) as an electron acceptor in living cell: a study on the JTC-3 and HeLa cells in culture.


A histochemical study on the structural differences of motor endplate in the red, white and intermediate muscle fibers of mouse limb muscle.


Heart weight of Jamaicans. Autopsy study of normal cases and cases of hypertension and chronic lung disease.


On the relationship of vascular wall and connective tissue. Histological, immunological and radiochemical investigations.


Analysis of experience in workmen's compensation for heart cases. Factors influencing the decision re compensability in heart attacks occurring among industrial workers.


You take him as you find him.

You take him as you find him.


Severe mucocutaneous and systemic reactions to drugs occurring in five patients during treatment for pulmonary tuberculosis.


A comprehensive care program for children with handicaps.


The "D" syndrome. Report of four trisomic and one D/D translocation case.


Morphological Philadelphia chromosome. Occurrence in a child with congenital anomalies.


Hepatic ultrastructure in the Hurler syndrome.


Formal discussion: future prospects in leukemia chemotherapy.


Phytohaemagglutinin on maternal and umbilical leukocytes.


Cellular antibody in mice bearing Ehrlich cancer. II. Properties of lymphoid cells from sensitized animal.


Connotative reactions of college students to disability labels.


The control system governing bone growth in response to mechanical stress.


Tuning forks. A diagnostic aid in hearing loss.


A history of the therapy of angina pectoris.


Battered child syndrome.

Battered child syndrome.


Carcinoma of the cervix in young women.

Carcinoma of the cervix in young women.


Obstruction of the superior vena cava.

Obstruction of the superior vena cava.


Dissociation of a complex of F-actin and H-meromyosin by addition of adenosine triphosphate.


Biophysical and biochemical studies of healing fractures, with special reference to glycoaminoglycans.


Cardiovascular abnormalities in infants malnourished before birth.


Dental and facial characteristics in Down's syndrome. (Mongolism).


Management of crushed chest injuries.

Management of crushed chest injuries.


The radioisotope blood pool scan.

The radioisotope blood pool scan.


Evaluation of rehabilitation in home or clinic setting: problems in methodology.


Histochemical studies on the adrenal medullary cells of the marmoset (Callithrix jacchus).


Suggestions for a histochemical terminology of carbohydrate-rich tissue components.


The yaws elimination campaign in Malaya.


The rehabilitation of severely disabled boys.


University education and personality problems of undergraduates.


A report of the incidence of positive tuberculosis skin test reactors and the incidence of active Tuberculosis among school children in the Methodist schools, Kapit district, Sarawak, Malaysia.


Investigation of ophthalmological conditions in Kelantan.


A rapid method for the identification of Candida albicans by the use of a serum--glucose preparation.