A comparative epidemiologic study of fractures among Indian, Malay and Swedish children.


Uric acid diathesis as met with in Kuala Kangsar district hospital.


Religion and physical disability.

Religion and physical disability.


Human and veterinary medicine.

Human and veterinary medicine.


The role of the pharmacist in the community.


MEND, a rehabilitation program.

MEND, a rehabilitation program.


An energy-dependent hydrogen-evolution from dithionite in nitrogen-fixing extracts of Clostridium pasteurianum.


Symptoms and pathology produced by toxic Microcystis aeruginosa NRC-1 in laboratory and domestic animals. Toxicity tests with lyophilized M. aeruginosa NRC-1 cells have been conducted using mice, guinea pigs, rabbits, chickens, ducks, two calves and one lamb as the test animals. The symptoms and pathological changes are described. On an equivalent weight basis it required three to five times the oral dosage to kill the large animals and birds as it did to kill the laboratory animals. The symptoms were less pronounced and the survival times were longer in the more resistant animals. Enlargement and congestion of the liver with necrosis of the hepatic cells were constant and pathognomonic. These findings are in general agreement with the observations of other workers who have examined the toxicity of naturally occurring Microcystis waterblooms. The toxicities and structures of microcystin and of six other biologically active cyclic polypeptides are summarized. The pathological effects produced by microcystin in laboratory and domestic animals resemble those produced in man but differ from those produced in animals by the toxic peptides of Amanita phalloides.


Effects of parathyroid hormone and other proteins in vitro on mitochondrial metabolism.


Preliminary bluetongue Transmission with the sheep ked Melophagus ovinus (L.). Five experiments indicated that the sheep ked MELOPHAGUS OVINUS (L.), can transmit bluetongue virus (BTV) in sheep. It was not determined whether these were mechanical or biological transmissions, although the results suggested mechanical transmission. Sheep keds were manually transferred from a BTV-host sheep to 18 susceptible test sheep. Of these, 10 were positive (5 with mild reactions), 6 questionable, and 2 negative for BTV. Three of the mildly reacting sheep and 3 of the questionable sheep had highly intensified reactions on challenge inoculation. Five of the positive sheep were immune on challenge inoculation. Blood from 2 positive reactors was subpassaged into susceptible sheep, which reacted with typical disease signs.


Epithelial inclusions of a bovine heart.


Microbiological transformations of terpenes. VI. Studies on the mechanism of some fungal hydroxylation reactions with the aid of model systems.


Hog cholera IV. Detection of the virus in tissue culture preparations by the fluorescent antibody technique. The fluorescent-antibody technique was employed for detection of hog cholera virus in tissue cultures inoculated with spleens of infected animals. As controls, cultures were also inoculated with material from normal swine and from those infected with other agents. In the first series 71 of 73 infected spleens, or 97 per cent, were detected. There were no false positive reactions among the controls. Results obtained with the second series of pigs showed that spleens collected during advanced stages of the disease were more satisfactory specimens than those collected earlier during the high temperature phase of infection. Findings with the third series of older swine indicated that their spleens were less satisfactory as a source of virus than those from young pigs. Tissues from freshly killed animals provided better specimen material than those from animals which had died.


Bacterial metabolism of hydroxyproline. I. Metabolism of L-allohydroxyproline by a Pseudomonas.


Bacterial metabolism of hydroxyproline. II. Metabolism of L-hydroxyproline in Achromobacter.


An occupational therapist's role in oral hygiene for the handicapped.


Distribution of alpha-glucosidase activities in human & monkey small intestine.


Synthesis of serum proteins in carbon tetrachloride injured rat & effect of vitamin B12 protection.


Incorporation of orotic acid-14C in a logarithmically growing culture of Escherichia coli.


A critical study of the conditions for colorimetric estimation of serum transaminases. I. Estimation of small amounts of pyruvic acid in the presence of ketoglutarate using dinitrophenylhydrazine.


Changes in the composition of striated muscle proteins of rat at different stages after birth.


Studies on hepatic glycogenolysis in protein malnutrition.


A comparative study on the release of peptides from buffalo & cow milk caseins by trypsin.


Haemagglutinins of field bean (Dolichos lablab). I. Isolation, purification & properties of haemagglutinins.


Studies on the proteose-peptone fraction of milk: isolation & properties of proteose-peptone & proteose from cow & buffalo milk.


Haemagglutinins of field bean (Dolichos lablab). II. Effect of feeding field bean haemagglutinin A on rat growth.


Essential amino acid requirements of the silkworm, Bombyx mori L.


Finger print patterns of peptic and alpha-chymotryptic digests of ox liver and erythrocyte catalases.


Record of the guinea worm-Dracunculus medinensis in an Alsatian bitch.


Lactic acid & lactic dehydrogenase activity in the blood of patients with essential hypertension.


Effect of plasmin on outflow resistance in the primate eye.


Marquio's disease.

Marquio's disease.


The evaluation of verbal performance in multiply handicapped blind children.


The primary histologic lesion of seborrheic dermatitis and psoriasis.


Occupational disease.

Occupational disease.


Right ventricular hypertrophy at high altitude.


Incorporation of D-[I-14C]galactosamine into serum proteins and tissues of the rat.


Hexosamine and acid glycosaminoglycans in human teeth.


Acid mucopolysaccharides of tadpole tail fin and back skin.


Acid mucopolysaccharide composition of human-heart valve.


Isolation of neutral sugar-containing mucopolysaccharides from cattle retina.


The effect of sulfate deficiency on the mechanical strength of the rat's aorta.


The isolation of a dermatan sulphate-protein complex from bovine heart valves.


The activation of mitochondrial adenosine triphosphatase by calcium.


The interaction of collagen and acid mucopolysaccharides. A model for connective tissue. 1. The interaction of acid mucopolysaccharides of connective tissue with solubilized collagen of native, or near-native, structure was investigated by free solution electrophoresis at pH7.0. 2. Complex-formation was detected by the appearance of a third peak in the ascending limb only, indicating reversible association. 3. Complex-formation was destroyed by prior heating of solubilized collagen, indicating a probable requirement for high molecular weight or internal structure of the protein. 4. Hyaluronate and chondroitin sulphate of mol.wt. 50000 gave complexes with soluble collagen at I 0.4, whereas heparin and chondroitin sulphate of mol.wt. 15000-18000 did not. All mucopolysaccharides yielded complexes at I 0.1. The stability of the complex appears mainly dependent on electrostatic forces and is increased with increase in chain length of the polysaccharide. 5. Solubilized collagen interacted to yield gels with the ;native' chondroitin sulphate-protein macro-molecule from cartilage. 6. A schematic model for the interaction of collagen and chondroitin sulphate-protein macromolecules shows parallel-ordered interaction of collagen fibrils with chondroitin sulphate side chains of the chondroitin sulphate-protein macromolecule. The biological implications of this model are discussed, particularly in relation to the ordered structures and the ionic-network properties of the intercellular components of connective tissue.


An adenosine triphosphatase from frog gastric mucosa.


Histologic changes produced by endotracheal intubation.


The accumulation of sodium and calcium in a specific layer of frog skin.


The painful shoulder. The scapulocostal syndrome in shoulder pain.


Structure of a polysaccharide protein complex.


Variations in lipid intake and their influence on respiration and tricarboxylic acid cycle activity.


A study on dermatitis in rice farmers.

A study on dermatitis in rice farmers.


Meiosis in a male with Down's syndrome.

Meiosis in a male with Down's syndrome.


A new deal for the aged and disabled.

A new deal for the aged and disabled.


Cardiomegaly after repeated application of isoprenalin in the rat.


Heart attacks and workmen's compensation acts.


Model train helps the limbless.

Model train helps the limbless.


The social distance of the exceptional: a study at the high school level.


The role of phosphofructokinase in metabolic regulation.


Effect of changes in hormonal and dietary status of rats and mice on the activity of their liver glutamic dehydrogenases.


The abdominal neourethra.

The abdominal neourethra.


Toxic epidermal necrolysis (the scalded skin syndrome). Its association in two cases with pathogenic staphylococci and its similarity in infancy to Ritter's disease.


A symmetrical simultaneous paried comparison of triamcinolone acetonide ointment and cream.


Electromyographic validation of pain relief: a pilot study in orthopedic patients.


Investigations on a plasminogen activator in two blood-suckers, Rhodnius prolixus Stål and Hirudo medicinalis.


Studies on acid mucopolysaccharides of pig gastric mucin. II.


Modification of breakage and reunion in relation to lethal damage.


A family study of Huntington's chorea with unusual manifestations.


State or Federal Workmen's Compensation--a conflict.


Progress in workmen's compensation.

Progress in workmen's compensation.


Progress in rehabilitation of the injured worker.


Dehydroepiandrosterone in human seminal plasma.


Psychiatry and the rehabilitation of the physically disabled.


Diagnosis of Hurler's syndrome in the hospital laboratory and the determination of its genetic type.


Indication for an allosteric effect of ADP on actomyosin gels and glycerinated fibres from insect fibrillar flight muscle.


Clinical experiences in ureteroileocutaneostomy.


Modern cytogenetic technics. Clinical review of chromosomal analyses in a children's hospital.


The direction of animal care.

The direction of animal care.


Spontaneous tumors in the Mongolian gerbil.


The coronary spectrum. Essentials of the legal issues in workmen's compensation.


A comparison of the growth and fat utilization of Caesarean-derived and conventional albino rats.


Paraldehyde: an anesthesia for recovery experiments in albino rabbits.


Pasteurella pneumotropica: cultural and biochemical characteristics, and its association with disease in laboratory animals.


Normal values for hemoglobin concentration and cellular elements in the blood of Mongolian gerbils.


The sterilisation of laboratory animal diet by ethylene oxide.


The care, handling and anesthesia of the snowshoe hare (Lepus americanus).


The metabolism, pulse rate and body temperature of normal, thyroidectomized and hypermetabolic rats.


Semi-automatic recording and electronic processing of chronic rat toxicity data.


A study of the efficacy of thiabendazole and dithiazanine iodide-piperazine citrate suspension against intestinal parasites in the Macaca mulatta.


Environmental factors influencing stereotyped and allelomimetic behavior in animals.


A comparison of the hemograms of conditioned and non-conditioned laboratory dogs.


A foot-operated watering device for use with special fluids.


The faultless mouse holder.

The faultless mouse holder.


A technique for prolonged infusion of rats.


The mansion on Richmond Hill.

The mansion on Richmond Hill.


Symposium: The handicapped child.

Symposium: The handicapped child.


Neuro-muscular transmission in the kitten. A preliminary note.


Potassium transport and control of glycolysis in human erythrocytes.


Effects of vitamin A on mucopolysaccharides of rat blood platelets.


Studies of enzyme systems utilizing automated methodology.


Burn wound complication.

Burn wound complication.


Twins, probably monozygotic: one mongoloid with 48 chromosomes, the other normal.


The relation of the light-dependent and light-triggered adenosine triphosphatases to photophosphorylation.


An effective oral antifungal for chronic infections in the aged.


Onychomycosis treated with ultrafine griseofulvin.


Care and raising of newborn baboons.

Care and raising of newborn baboons.


The need for a large standard laboratory dog.


The trematodes of laboratory primates.

The trematodes of laboratory primates.


A method for intravenous injection and collection of blood from rats and mice without restraint and anesthesia.


The hematogram of the squirrel monkey (Saimiri sciureus).


The germfree cat.

The germfree cat.


Successful prevention of infantile diarrhea of mice during an epizootic by means of a new filter cage unopened from birth to weaning.


A device to restrain the mouse, rat, hamster and chinchilla to facilitate semen collection and other reproductive studies.


Small laboratory animal feeding technique.


A rat resuscitator.

A rat resuscitator.


Infertility of guinea pigs on sawdust bedding.


Enzyme-histochemical studies on the healing process of split skin grafts. II. 5-Nucleotidase, adenosinetriphosphatase, acid and alkaline phosphatase in autografts.


Nicotinamide content of insects.

Nicotinamide content of insects.


Studies with the ATPase of adrenal medulla.


Lysogenic conversion of staphylococci to loss of beta-toxin.


The autolysis of Clostridium sporogenes.


Heart size after isolated replacement of mitral or aortic valve.


Arthus-like reaction of skin allograft (homograft) induced by serum antibodies.


Panel on medicolegal considerations in workmen's compensation.


Eradication of bovine brucellosis in Moscow region.


The influence of rotation of the trunk on the anatomy of the inguinal canal.


Disorders of the hair and their treatment before the 18th century.


The pesticide problem--return to sanity.


Technical errors in peritoneoscopy.

Technical errors in peritoneoscopy.


Enzyme nomenclature. Recommendations of the International Union of Biochemistry.


Some questions of diagnosis of brucellosis and specific preventive measures in the Kazakh Soviet Republic.


Nicotinamide deamidase from rabbit liver.


Extracellular space in the central nervous system.


The influence of parathyroid extract on phalanges of the embryonic fowl in vitro.


The occurrence of some carbohydrates and collagen in Obeliscoides cuniculi (Graybill, 1923), a nematode parasite of the rabbit.


Congenital defects involving the abdominal wall, sternum, diaphragm and pericardium: case report and review of embryologic factors.


Early loss of teeth in children.

Early loss of teeth in children.


Acrodynia or pink disease.

Acrodynia or pink disease.


Massive melena.

Massive melena.


Diagnosis and treatment of parathion poisoning.


Molecular events resulting in radiation injury, repair and sensitization of DNA.


Annual report: Arkansas State Board of Health.


Appendicitis in pregnancy.

Appendicitis in pregnancy.


The compromised fetus.

The compromised fetus.


Arkansas morbidity--1965.

Arkansas morbidity--1965.


The nursing situation.

The nursing situation.


Application of psychological principles to dental practice.


Premedication for children.

Premedication for children.


The impact of water fluoridation on the practice of dentistry for children.


The effect of appointment length on behavior of the pedodontic patient and his attitude toward dentistry.


The psychological preparation of the child for dental surgery. II.


Activity projects.

Activity projects.


Preparatory training bureau.

Preparatory training bureau.


Banstead Place.

Banstead Place.


Measurement of anxiety in children during routine dental procedures.


What do Georgia dentists think about dentistry for mentally retarded children?


Dental care for children.

Dental care for children.


Dental problems and programs for the chronically ill and aging.


The effectiveness of the electric toothbrush in reducing oral debris in handicapped children.


Independence in a wheelchair; useful booklet for the disabled.


Industrial dermatitis.

Industrial dermatitis.


Dentistry's new horizon--dentistry for the handicapped.


The long struggle against crippling disease.


Dental care for retarded children.

Dental care for retarded children.


John Groom's crippleage.

John Groom's crippleage.


The composition of the cell wall of Lactobacillius bifidus var. pennsylvanicus.


The effect of quinidine on the activity of a sodium-potassium activated, magnesium-dependent ATPase enzyme isolated from toad cardiac muscle.


A cation activated adenosinetriphosphatase in cell membranes of halophilic Vibrio parahaemolyticus.


The effect of carnosine on myofibrillar ATPase activity.


Depression of facilitatory influences on spinal motor activity by carisoprodol.


Staphylococci in man and animals. Distribution and characteristics of strains.


Diagnostic considerations in management of penetrating abdominal wounds.


Experiences with peritoneoscopy at Walter Reed General Hospital, 1964-1965.


The management of gunshot wounds of the extremities.


Neurologic phenomena of leukemia.

Neurologic phenomena of leukemia.


Urinary output of total and individual fractions of 17-ketosteroids in patients with acne.


Massive left atriomegaly.

Massive left atriomegaly.


Thyrocardiac disease--fact or fancy?

Thyrocardiac disease--fact or fancy?


Contact dermatitis caused by the 'manzanillo' (Rhus striata) tree. Report of three cases.


Rupture of the inferior epigastric artery with rectus-sheath hematoma.


Limitations of the electrocardiographic diagnosis of ventricular hypertrophy.


The failure of some aromatic amines to produce hemiglobin in vivo in spite of microsomal N-hydroxylation.


The low activity of aniline in producing hemiglobin in rabbits.


The formation of hemiglobin by p-hydroxylaminobenzenesulfonamide in vivo and in vitro.


How a pharmaceutical manufacturer tests products for sterility.


Clean room garment selection and care.

Clean room garment selection and care.


Emerging problems in oral health care and clinical research in a chronic disease hospital.


Regulation of metabolism in working muscle in vivo. II. Concentrations of adenine nucleotides, arginine phosphate, and inorganic phosphate in insect flight muscle during flight.


Studies on thymidine kinase of human liver cells in culture.


Special schools over a century.

Special schools over a century.


Wheel-chairs on the campus?

Wheel-chairs on the campus?


Cerebral biopsy in the investigation of presenile dementia. I. Clinical aspects.


Salutary effects of prochlorperazine on chronic psychotic choreo-athetosis.


Role of phospholipid in the activation of Na+, Ka+-activated adenosine triphosphatase of beef brain.


Cellular response of seborrheic keratosis following croton oil irritation and surgical trauma with special reference to melanoacanthoma.


Visual discrimination learning in imbecile children with nonreinforcement of irrelevant tendencies.


The nucleoli in mitotic divisions of mammalian cells in vitro. In a number of mammalian cell strains nucleoli persisted through mitosis. This phenomenon was especially pronounced in several cell lines derived from Chinese hamster tissues. All the methods employed, including radioautography with tritiated uridine, cytochemical stains (methyl green-pyronin and azure B), fluorescent microscopy (coriphosphine O), ribonuclease digestion, and electron microscopy, demonstrated that the bodies identified as persistent nucleoli in the mitotic stages had the same characteristics as did the nucleoli in the interphase. Persistent nucleoli may attach to the chromosomes or may be free in the cytoplasm. In cells where no persistent nucleoli as such were noted, nucleolar material was observed to attach to the chromosomes in shapeless masses which moved with the chromosomes during anaphase. At least a portion of the nucleolar material was included in the daughter nuclei, presumably for immediate use for protein synthesis after cell division.


Poison ivy in Melbourne.

Poison ivy in Melbourne.


Density gradient separation of sarcotubular vesicles and other particulate constituents of rabbit muscle. Separation of particulate matter in rabbit muscle extracts by differential centrifugation leads, in first approximation, to the isolation of fraction I (15,000 to 41,000 g) and fraction II (41,000 to 150,000 g). The former consists mainly of sarcotubular material, actively transporting calcium ions, and displaying relaxation factor activity. The latter is heterogeneous, shows little calcium accumulation, and contains factors both inhibiting and activating myofibrillar ATPase. Fraction I is resolved by density gradient centrifugation into 2 main subfractions. The lighter one represents sarcotubular material in the best state of preservation, with biochemical activities stable for weeks in the cold. The heavier one may consist of the same material in a less well preserved form. Upon aging, it develops an activating activity toward myofibrillar ATPase, when the relaxing effect has declined. Fraction II is resolved by density gradient centrifugation into 3 or more fractions, with some variability. Relaxing activity in terms of inhibition of myofibrillar ATPase predominates among the lighter subfractions, increase of ATPase among the heavier. The intrinsic ATPase of fraction II is activated by calcium ions, but there is little or no bulk accumulation of calcium oxalate. Nevertheless, its limited calcium uptake seems to suffice to explain its relaxing activity. The particulate material contains mucopolysaccharide and lipid. Most of the lipid in fraction I is phospholipid; in fraction II this is less than half, if calculated as lecithin. The unfractionated material contains an adenylcyclase. There is no acetylcholine esterase.


Comparative studies on serum lipids and histochemical features of the arterial wall in animal species differently susceptible to experimental atherosclerosis.


Camping for crippled children.

Camping for crippled children.


The effect of hydrocortisone on chondroitin sulfate production and loss by embryonic chick tibiotarsi in organ culture.


Separation of acid polysaccharides by starch gel electrophoresis.


The complex nature of phosphofructokinase - a nucleic acid containing enzyme.


On the functional significance of the nucleic acid - protein complex of phosphofructokinase.


Physical education in a rehabilitation center.


Distribution of mucopolysaccharides in the human vascular tree.


Sulfur mustard: reaction with L-cells treated with 5-fluorodeoxyuridine. After exposure to 5-fluorodeoxyuridine, L-cells are considerably more sensitive to the lethal effect of sulfur mustard than after they have been released from this block by addition of thymidine and allowed to proceed into the G2 phase of the division cycle. Nevertheless, for both populations, the amounts of mustard bound per cell and per nucleus (expressed as the amount of mustard per unit of protein) were the same. Likewise, the amounts of mustard bound per unit of DNA were the same for both populations.


Further studies on the myofibrillar adenosine triphosphatase-inhibitory activity and the Mg++-dependent adenosine triphosphatase of the relaxing granules.


Effect of sample site on fatty acid composition of adipose tissue.


Discharges of semitendinosus fusimotor neurones in the decerebrated and spinalized rabbit.


Uptake of fibrinogen and fibrinolytic enzymes by neoplastic tissue.


Cardiac hypertrophy after muscular stress. Myocardial lipids modifications in rat.


The role of cardiac enlargement in the production of musical pericardial sounds.


Oxidative phosphorylation in Nitrobacter winogradskyi.


The effect of sulphydryl-blocking reagents and of urea on the (Na+ + K+)-activated enzyme system.


The reticulocyte count in mongols.

The reticulocyte count in mongols.


Ovalocytosis in normal and mentally retarded subjects.


The absorption spectra of protoheme and heme a complexes with amino acids and related compounds.


The effect of tripropyltin chloride on myosin A adenosine triphosphatase.


Enzyme histochemistry of skeletal muscle.


Acne vulgaris and systemic antibiotics.

Acne vulgaris and systemic antibiotics.


Antibiotics and the placebo reaction in acne.


Objective evaluation of demethylchlortetracycline hydrochloride in the treatment of acne.


Bacteriophage therapy in infective childhood asthma.


Analysis of the check reflex.

Analysis of the check reflex.


Reproduction in down's syndrome (mongolism): chromosomal study of mother and normal child.


Actin-myosin interaction: inhibition of the myosin adenosine triphosphatase by actin. In the absence of magnesium ion, the addition of actin to myosin in a 1 :4 ratio has a strong inhibitory effect on the adenosine triphosphatase activity, in contrast to the well-known activating effect of actin in the presence of magnesium ion. This finding suggests that both effects result from a conformational change in the active site of the myosin adenosine triphosphatase.


Localization of mitochondrial adenosine triphosphatase activity in cultured human cells.


Diurnal variation in some Krebs cycle enzymes in cactus (Nopalea dejecta) phylloclades.


Studies on enzymic synthesis of cerebroside sulphate from 3'-phosphoadenosine-5'-phosphosulphate.


Oxidative enzymes in Escherichia coli plasma membrane.


Exocellular deoxyribonuclease I of Penicillium chrysogenum: I--Partial purification & properties of the enzyme.


Intracellular localization & characteristics of lactate dehydrogenase activity of Salmonella typhosa (NCTC 8385).


Tricarboxylic acid cycle activity in a pseudomonad.


The biochemistry of Vibrio cholerae: IV--Acid soluble nucleotide constituents.


Effect of ultraviolet radiation on the oxidation of certain Krebs cycle substrates in Vibrio cholerae.


Hormonal effect on certain glycolytic enzymes of rat mammary gland.


Utilization of some amino acids by human malignant cervix uteri.


Tricarboxylic acid cycle activity in human malignant cervix uteri.


Immunochemical characterization of sheep plasma glycoprotein.


Release of sialic acid from caseins of cow & buffalo milk by cow & buffalo rennets.


Biochemical alterations in rat tissue in iron deficiency anaemia & repletion with iron.


Interrelationship of dietary protein & vitamins on metabolism: I--Interdependence of the levels of certain B vitamins & dietary protein.


Mode of action of psoralen in pigment production: 3--Photo-oxidation of dihydroxyphenylalanine in the presence of psoralen.


Fatty acid composition of phosphatidyl ethanolamine of Mycobacterium tuberculosis.


Polyguanylic acid & its effect on amino acid incorporation.


Proteins in human milk.

Proteins in human milk.


Electrophoretic studies on cytoplasmic proteins from human malignant cervix uteri.


Chromosome structure in phage T4, II. Terminal redundancy and heterozygosis.


Additional evidence for two kinds of heterozygotes in phage T4.


The genetic structure of complementation heterozygotes.


Synaptic activity in motoneurons during natural stimulation of muscle spindles. Synaptic activity evoked in cat motoneurons during stretch stimulation of muscle spindles in the homonymous muscle has been studied by intracellular recording. A class of miniature excitatory postsynaptic potentials evoked by such physiologic stimulation results from activity in single group la spindle afferent fibers, and the criterion for identification is a predictable pattern of rhythmic occurrence of the synaptic potentials. Statistical examination of the amplitude distributions of this class of miniature synaptic potentials suggests that some group Ia fibers liberate a relatively large number of quantal excitatory postsynaptic potential units per fiber impulse.


Mucopolysaccharides: N-acetylglucosamine- and galactose-6-sulfates from keratosulfate. Galactose-6-sulfate and N-acetylglucosamine-6-sulfate were obtained pure from a partial acid hydrolyzate of corneal keratosulfate by paper chromatography and electrophoretic fractionation. These sugars were also present in hydrolyzates of skeletal keratosulfate. The distribution of the sulfate groups in the various keratosulfates might depend upon their source, and this distribution probably has important biological significance.


A controlled trial of rehabilitation.

A controlled trial of rehabilitation.


Door handles for the disabled. An assessment of their suitability.


Keratoelastoidosis marginalis of the hands. Synonyms: marginal keratoderma of palms; degenerative collagenous plaques of the hands.


A new antibiotic against gonorrhea.

A new antibiotic against gonorrhea.


Cytogenetic survey of 225 patients diagnosed clinically as mongols.


A survey of attitudes toward the training and employing of physically handicapped speech pathologists and audiologists.


Water extrusion in isolated subcellular fractions. V. Adenosinetriphosphate hydrolysis by mitochondria during the reaction.


The mucopolysaccharides of avian oviduct, egg, skin, and comb, and of porcine skin.


Griseofulvin and lupus erythematosus.

Griseofulvin and lupus erythematosus.


Action and indications for solid carbon dioxide therapy in dermatology.


Vectorcardiographic criteria of left and right ventricular hypertrophy with the Frank system.


Some histochemical observations on tissue of renal hypertensive animals.


Further experiences with guanethidine--a clinical assessment of 103 patients.


Trisomy D1 (13-15) in a Bantu child.

Trisomy D1 (13-15) in a Bantu child.


Neurons of intramural ganglia of the heart in its hyperfunction and hypertrophy.


Relationship between structure, specificity and genes within the ABO and Lewis blood-group systems.


The role of Mg2+ in the contraction and adenosine triphosphatase activity of myofibrils.


Metabolism in vivo of steroids in the canine ovary.


Carbonic anhydrase distribution in rabbit lens.


The chemical specificity of the mucopolysaccharides of the cornea.


Some glycolytic enzymes and intermediates in the rabbit lens.


Motor myoneural junctions on frog intrafusal muscle fibers.


In vitro studies of factors affecting penetration of duck erythrocytes by avian malaria (Plasmodium lophurae).


Demyelination regions of nerve fibers in frog muscle spindle as studied by serial sections for electron microscopy.


Congenital and acquired anatomic variations, including degenerative changes of the lower lumbar spine; role in production of painful back and lower extremity syndromes.


Acid mucopolysaccharides in the Rask-Nielsen transplantable mouse mastocytoma.


3',5'-diesters of 5-fluoro-2'-deoxyuridine: synthesis and biological activity.


Backache due to osteoporosis in an industrial population. A survey of 481 patients.


Children's orthopaedic surgery in the United States: historical trends.


Pedodontics--preventive and personal.

Pedodontics--preventive and personal.


Spondylopathy. A clinical study of backache in the aged.


The 99th Annual Session dedicated to Siskin brothers.


Repression of Staphylococcus aureus in associative culture. The growth of Staphylococcus aureus MF 31 was suppressed when grown in association with Streptococcus diacetilactis and other lactic streptococci. The data indicated that the initial proportion of staphylococci present in the medium was of less importance than the depletion of vital nutrients. Investigation revealed that factors present in Yeast Nitrogen Base medium could reverse the inhibition which was due to antagonism. The major factor found was nicotinamide, and further study revealed that the biological availability of this compound was influenced by the pH of the medium. The addition of nicotinamide to depleted media with careful control of the pH resulted in increased growth of S. aureus in the test system. Further data indicated that additional factors may affect the degree of growth by S. aureus in depleted media.


Bacteriophage inhibition in staphylococci.


Cardiovascular actions of the hypotensive agent, N, N-Diallylmelamine (U-7720).


The preparation of microsomes.

The preparation of microsomes.


A note on "cancer-susceptible" and "cancer-resistant" genotypes: implications for cancer detection and research.


Species differences in the hydroxylation of aniline and N-ethylaniline by liver microsomes.


An epidemiological approach to infant mortality in Omaha and Douglas County 1960-1964.


Beverage electrolytes at the Bishop Clarkson Memorial Hospital, Omaha, Nebraska.


Congenital strictures of the esophagus.

Congenital strictures of the esophagus.


Fluid balance--intake and output charts, a revised form.


The Penrose industrial health centre.

The Penrose industrial health centre.


Effect of glucocorticoids upon the mucopolysaccharide content of human skin.


Quinethazone photosensitivity dermatitis.


Corynebacterium acnes. Presence of complement fixing antibodies to corynebacterium acnes in the sera of patients with acne vulgaris.


Fungi in nails.

Fungi in nails.


Recovery of muscle spindle activity in cats after cerebellar ablation.


Workmen's compensation--a long journey forward.


Proteolytic activity in muscles of old animals.


Rapid separation of mucopolysaccharides by salt-gradient ion-exchange paper chromatography.


Flavin-linked dehydrogenation of ether glycols by cell-free extracts of a soil bacterium. Payne, W. J. (University of Georgia, Athens), and R. L. Todd. Flavin-linked dehydrogenation of ether glycols by cell-free extracts of a soil bacterium. J. Bacteriol. 91:1533-1536. 1966.-Cell-free extracts of bacterium TEG-5 grown on tetraethylene glycol dehydrogenated a variety of ether glycols and nonylphenoxy and secondary alcohol ethoxy derivatives. Nicotinamide nucleotides did not serve as electron acceptors, but ferricyanide was effective. Dialysis of crude extract depressed activity with tetraethylene glycol, which was restored then by flavine adenine dinucleotide (FAD) or boiled extract supernatant fluid (BES) but not by other flavins. Precipitatation of extract protein at pH 4.0 at 80% ammonium sulfate saturation dissociated FAD and yielded an inactive fraction. Activity was restorable by FAD and BES but not by other flavins. Ethylene glycol was not dehydrogenated by the acid ammonium sulfate fraction with FAD. Atabrine inhibited tetraethylene glycol oxidation, and the inhibition was relieved by FAD but not by other flavins. Tergitols which have sulfated ethoxy side chains on secondary alcohols were not dehydrogenated, but those with free ethoxy side chains on identical alcohols were.


Pediatric dentistry under general anesthesia.


Adenosine triphosphatase activity in 2 strains of Staphylococcus aureus differing in radiosensitivity.


Symposium: Analgesia in dental practice. 4. Analgesia in pedodontic practice.


Judicial vs. medical notice: coronary artery disease in industry.


The electromyogram in the evaluation of medicolegal and workmen's compensation cases.


Principles of public health importance in the management of a subhuman primate colony.


Schistosome dermatitis in association with rice growing in the northern territory of Australia.


Wheelchair users--a study in variation of disability.


The pattern of contact dermatitis due to occupation.


Hexosephosphate formation and the regulation of glycolysis in muscle.


Influence of induced tuberculin allergy followed by induced Arthus reaction on each other, in rabbits.


Coupling of ATP-hydrolysis with contraction of isolated myofibrillar fragments.


The effects of ethyl chloride on the muscle spindles of the triceps surae of the rabbit.


Kurloff body formation in the guinea pig lymphocyte.


Influence of rifamycins on glycolysis of rat brain.


Structure of heparitin sulfate in tissues of the Hurler syndrome.


Effects of ethanol on na, K, mg-stimulated microsomal ATPase activity.


Adenosinetriphosphatase activity in synaptic vesicles of rat brain.


Inhibition of testosterone stimulation of microsomal hexobarbital metabolism by 17-alpha-methyl-B-nortestosterone (SK&F 7690).


Preventable occupational dermatoses.

Preventable occupational dermatoses.


The family physician and Workmen's Compensation. Legal aspects.


Disability without disease or accident.

Disability without disease or accident.


Study on frequency of allergic manifestations and skin reactivity in children with Down's syndrome.


Protein metabolism requisite for cell division in Tetrahymena pyriformis.


Lipolytic activity of rat lungs in dependence on age.


The development of arginase and ornithine-transcarbamylase activities in the liver of rats.


Changes of proteolytic activity of proteins following denervation in the anterior and posterior latissimus dorsi of the chicken.


The effect of adrenalectomy and starvation on arginase and ornithine-transcarbamylase activities in the liver of rats during development.


Liberation from and uptake of non-esterified fatty acids into adipose tissue of rats with different work output.


Vesico-ureteral reflux in rabbits.

Vesico-ureteral reflux in rabbits.


The relation between spontaneous rhythmical variation in vasomotor excitability and conditioning of the vasomotor reflex to deep inspiration.


Development of the steady potential and high frequency impedance of the cerebral cortex in guinea-pig embryos.


A contribution to the analysis of the pulse rate during a load and recovery.


The relationship between calcium and chlortetracycline in the body.


Retraction and firmness of the fibrin clot.


Factors affecting the proteolytic activity in denervated muscle.


Rehabilitation of the disabled worker. I. An overall view of rehabilitation and workmen's compensation in New Jersey.


Pathological studies on mucopolysaccharide metabolism: experimental lathyrism and mucopolysaccharides.


Efficacy of 'dequinol' in the treatment of bovine balantidiosis.


Determination of glucosamine and galactosamine by gas chromatography.


Effect of metal-complexing agents on mucopolysaccharide sulfate biosynthesis.


The relation between DNA and protein synthesis in mouse fibroblasts.


Rehabilitation of the elderly patient.

Rehabilitation of the elderly patient.


The impaired aged. A follow-up study of applicants rejected by a voluntary home.


Seborrhoeic dermatitis.

Seborrhoeic dermatitis.


Mucopolysaccharides in synovial fluid detection of chondroitin sulphate.


Effect of a sulfated mucopolysaccharide (R01-8307) on the zona glomerulosa of the rat adrenal gland.


Urinary acid mucopolysaccharides.

Urinary acid mucopolysaccharides.


Influence of a cartilage bone marrow extract on mucopolysaccharide metabolism of cells cultured in vitro.


Comparison of therapeutically important antirheumatics on the basis of experimental results.


Reproductive biology--2000.

Reproductive biology--2000.


The peptides of amniotic fluid.

The peptides of amniotic fluid.


Nebraska history and medicine: A centennial.


The causes of labor.

The causes of labor.


Evaluation of the fetus in utero.

Evaluation of the fetus in utero.


Cellular production of gonadal steroid hormones.


Ultrasound in physiotherapy.

Ultrasound in physiotherapy.


Vitamin C deficiency and connective tissue. V. Fractionation of acid mucopolysaccharides in carrageenan-granulomas.


Our experience with the diagnosis of anomalies of the pulmonary venous return and their surgical treatment.


Vitamin C deficiency and connective tissue. IV. Determinations of mucopolysaccharides and collagen in carrageenan-granulomas.


Isolated (primary) chylopericardium. Diagnosis and surgical treatment.


Dogger Bank itch: survey of trawlermen.

Dogger Bank itch: survey of trawlermen.


Arsenicals for asthma.

Arsenicals for asthma.


An inhibitor of cholesterol biosynthesis and the alveolar macrophages. An accumulation of lipid material was observed in the alveolar macrophages of animals treated per os with an inhibitor of cholesterol biosynthesis (trans-1, 4-bis) (2-dichlorobenzyl-aminomethyl) cyclohexane dihydrochloride: AY-9944). This lipid is probably 7-dehydro-cholesterol which is a precursor of cholesterol and accumulates in various organs, especially in the lungs. In the rats and pigs the reaction is limited to the alveolar macrophages which are expectorated or degenerate. In dogs some of the alveolar macrophages are also expectorated while others continue to collect a cholesterol-like lipid until large crystals form, which provoke the formation of giant cells and later fibrocytes, giving rise to "cholesterol granulomata".


Feed manufacturers and the veterinarian.


The role of the food and drug directorate in the control of veterinary drugs.


Immunofluorescence study of wild rabies virus and antibody. A concentrate of wild rabies antibody was prepared from hyperimmune serums of three dogs refractory to wild rabies. The animals resisted repeated intramuscular injections of large doses of wild rabies virus in emulsions of whole brain, in emulsions of submaxillary salivary glands, and in emulsified mixtures of brain and submaxillary glands taken from naturally rabid dogs. The antibody was conjugated with fluorochrome and then absorbed by a procedure that gave "cell-free" working solutions of fluorescent antibody. The procedure entailed parallel absorption steps with minced pathological canine submaxillary glands from (1) naturally rabid dogs (these glands contained specific, undegraded, natural antigens of live wild rabies virus plus nonspecific substances and antigens) and (2) nonrabid dogs from a rabies endemic region (these glands contained nonspecific substances and antigens). Extracts from submaxillary glands of the three naturally rabid dogs and one nonrabid dog were stained with a cell-free solution of the fluorescent antibody. The glands of the rabid dogs contained fluorescent aggregates of intense green spherical and filamentous particles. When nonfluorescent canine hyperimmune serum was incubated with rabies-containing submaxillary extract, the rabies antigens were quenched. When nonfluorescent equine fixed virus antiserum was incubated with such extracts, the aggregates still retained bright fluorescence.


Psychology of children's dental treatment.


Pedodontics--a graduate discipline.

Pedodontics--a graduate discipline.


Disabled children and rehabilitation.

Disabled children and rehabilitation.


Orthodontics, pedodontics and the general practitioner.


Development of the resistance to general stagnant anoxia (ischemia) in dogs.


Human low-dosage parenteral methotrexate therapy. A controlled toxicity study.


The use of gas-liquid chromatography in the analysis of neutral monosaccharides in hydrolysates of gastric mucopolysaccharides. 1. Conditions are described for the separation and estimation of the neutral monosaccharides obtained on acidic hydrolysis of human gastric mucopolysaccharides. 2. The technique involves the formation of the trimethylsilyl derivatives of the sugars and the analysis of these by gas-liquid chromatography. 3. The monosaccharides estimated in gastric mucopolysaccharides by this technique were l-fucose, d-mannose, d-galactose and d-glucose. 4. The analytical values for glucose and fucose obtained by this method agreed well with values obtained by the glucose oxidase and thioglycollic acid methods respectively. 5. Evidence is presented which clearly indicates that gas-liquid chromatography is a faster, more sensitive and more convenient technique for the measurement of these compounds than any other in use at present.


Why the Apollo contamination control handbook?


Is your cleaning solvent compatible? Asks speaker.


Distribution of sodium-plus-potassium-stimulated adenosine-triphosphatase activity in isolated nerve-ending particles. 1. A rapid method for the isolation of nerve-ending particles from brain is described. This involved the centrifugation of the large-granule fraction over a discontinuous density gradient consisting of 3% (w/v) and 13% (w/v) Ficoll dissolved in 0.32m-sucrose. The results of the biochemical as well as morphological identification of nerve-ending particles are given. 2. Approx. 20% of the (Na(+)+K(+))-stimulated adenosine-triphosphatase activity originally present in the cerebral grey-matter suspension was recovered in the fraction consisting principally of large nerve-ending particles (approx. 1mu in diameter). The activity of the adenosine triphosphatase/mg. of protein in the nerve-ending fraction approximated to that in the small-granule fraction after the treatment with glycol ether diamine-tetra-acetic acid. The conclusion was drawn that the synaptic structure, supposedly the limiting membrane of the nerve-ending particle, is one of the feasible sites of localization of the (Na(+)+K(+))-stimulated adenosine-triphosphatase activity in cerebral tissues. Adenosine triphosphatase in purified cerebral mitochondria was not stimulated by Na(+). 3. No qualitative differences were found between the (Na(+)+K(+))-stimulated adenosine-triphosphatase activities exhibited by the nerve-ending particles and by the cerebral small-granule fraction with respect to pH-dependence, cation requirements and susceptibility to ouabain.


Open-end clean room at Collins Radio flexible, expandable and economical.


Applying "downflow" to dust-fume control in a plastics facility.


Contamination control for a precision photogrammetric lab.


Understanding fluctuations in airborne contamination.


Hospital use of sterile "patient isolators".


Maximizing functional abilities of the disabled.


An endogenous mechanism of increased vascular permeability in allergic inflammation: purification of permeability factors newly isolated from Arthus lesion and their biologic significance.


An endogenous mechanism of increased vascular permeability in allergic inflammation: reproduction of vascular response by Arthus permeability factor in rabbit skin.


p-Aminohippurate and N-methylnicotinamide transport in dog renal slices--an evaluation of the counter-transport hypothesis.


The mechanism of reflex irradiation.

The mechanism of reflex irradiation.


Measurement of plasma 11-deoxy-17-ketosteroid sulfates by gas-liquid chromatography.


Biosynthesis of steroid sulfates by normal human testis.


Changing concepts in pedodontic education.


The production of phage structural proteins in single cells of Escherichia coli infected with phage T4.


Intensive care of the coronary patient.

Intensive care of the coronary patient.


Roentgenologic contrast studies in vascular disease.


Psychoactive drugs: review and overview. Review of sites of action, uses, dosage, side effects and contraindications of psychoactive drugs with proposed classification and suggested rules for prescribing.


The role of pelvic lymphadenectomy in the surgical management of early stage 1 carcinoma of the cervix.


Severe bronchial asthma: its pathology and treatment.


Tetanus.

Tetanus.


Electrocardiogram of the month.

Electrocardiogram of the month.


Blood pressure and toxemia of pregnancy.


Do not despair.

Do not despair.


Pharmacologic interference with mast cell degranulation induced by BW 48/80.


Modern management of hair and scalp disorders.


An investigation into the content of elastic tissue and muscle tissue in the aorta of some big and small mammals.


The influence of new guanidine derivatives on adrenergic nerve endings, ganglionic transmission and neuromuscular junction.


Potentiated premedication with ataraxics prior to stomatologic treatment of children and adolescents with psychiatric symptomatology. (Preliminary report).


Plasminogen-free proactivator B obtained from human plasma.


Stimulation of the coronary collateral circulation by lidoflazine (R 7904).


The antagonistic effects of sodium and calcium on the action potential of guinea pig papillary muscle.


Skin disease in the Venda.

Skin disease in the Venda.


Receptor potentials and impulse generation in the isolated spindle during controlled extension.


Response of the isolated muscle spindle to different rates of stretching.


The dual role of sensory systems: detection and setting central excitability.


Technique for separation and estimation of androsterone, aetiocholanolone and dehydroepiandrosterone by use of thin-layer chromatography.


Some aspects of the aetiology of acne vulgris.


Occupational and nonoccupational exposures to asbestos.


Dust diseases and workmen's compensation. U.S. Department of Labor, Bureau of Labor Standards, August 1964.


Amino acid metabolism in patients with Hurler's syndrome.


Release of plasminogen activator by the isolated perfused dog kidney.


The future of pedodontics.

The future of pedodontics.


Preparation of the specialists in pedodontics.


Hospital procedures in the care of the handicapped child.


An injection procedure for the child dental patient.


Rubber dam technique in pedodontics.

Rubber dam technique in pedodontics.


Stainless steel: its use in pedodontics.


Plastics in pedodontics.

Plastics in pedodontics.


Pulpal therapy in primaryand young permanent teeth.


Traumatized primary teeth.

Traumatized primary teeth.


Pediatric exodontia.

Pediatric exodontia.


Treatment of dentitions affected by hereditary amelogenesis and dentinogenesis imperfecta.


The versatile occlusal dental x-ray film. 3. A new pedodontic survey.


A new cortical area receiving input from group I muscle afferents.


Alkylation of a brain transport adenosinetriphosphatase at the cardiotonic steroid site by strophanthidin-3-haloacetates.


6-alpha-hydroxylation in human placenta perfusion.


Conversion of dehydroepiandrosterone sulfate to androst-5-enediol-3-sulfate by soluble extracts of rat testis.


Natriuretic action of certain adrenocortical androgens.


Some problems encountered in the assay of complement.


Crystallization of the Dick toxin.

Crystallization of the Dick toxin.


Sodium-potassium dependent adenosine triphosphatase of mammalian reticulocytes and mature red blood cells.


In vitro testosterone synthesis by rat testicular tissue.


Newborn organ abnormalities. A guide to abnormal maternal glucose metabolism.


Pedodontic utilization of contributions made by operative dentistry, dental materials, and prosthodontics.


N-Hydroxylation of 2-aminofluorene in the guinea pig and by guinea pig liver microsomes in vitro.


Investigation of certain links in the photoenzymochemical chain of processes in photoreceptors.


The hydrolysis of acetanilide and some of its derivatives by enzymes in the microsomal and soluble fraction prepared from livers of various species.


Local authority welfare services for the handicapped.


Viral-induced bacterial toxins.

Viral-induced bacterial toxins.


Congenital beta-lipoprotein deficiency.

Congenital beta-lipoprotein deficiency.


The XXXXY chromosome anomaly: report of three new cases and review of 30 cases from the literature. The majority of abnormal sex chromosome complexes in the male have been considered to be variants of Klinefelter's syndrome but an exception should probably be made in the case of the XXXXY individual who has distinctive phenotypic features. Clinical, radiological and cytological data on three new cases of XXXXY syndrome are presented and 30 cases from the literature are reviewed. In many cases the published clinical and radiological data were supplemented and re-evaluated. Mental retardation, usually severe, was present in all cases. Typical facies was observed in many; clinodactyly of the fifth finger was seen in nearly all.Radiological examination revealed abnormalities in the elbows and wrists in all the 19 personally evaluated cases, and other skeletal anomalies were very frequent. Cryptorchism is very common and absence of Leydig's cells may differentiate the XXXXY chromosome anomaly from polysomic variants of Klinefelter's syndrome. The relationship of this syndrome to Klinefelter's syndrome and to Down's syndrome is discussed.


Federal legislation and the smaller health care facility. More and better services needed for the physically disabled.


The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man. The mechanisms of the aldosterone-inhibiting and antihypertensive actions of heparin and certain other sulfated mucopolysaccharides were investigated in 13 hypertensive patients. N-formyl chitosan polysulfuric acid (RO 1-8307) was used rather than heparin because of its low anticoagulant activity. RO 1-8307 lowered aldosterone secretion in one patient with proved and one with probable primary aldosteronism; this indicates that the mucopolysaccharide does not inhibit aldosterone secretion via the renin-angiotensin mechanism. In six hypertensive patients RO 1-8307 caused a fall in the secretion of aldosterone and its probable immediate precursor, 18-hydroxycorticosterone; therefore it does not act at the last step in the synthesis of aldosterone. RO 1-8307 produced a prolonged clinical and biochemical remission in the two patients considered to have primary aldosteronism but did not influence blood pressure in five of seven patients in whom excessive aldosterone was probably not a major factor in the hypertension. It is concluded that the antihypertensive action of RO 1-8307, and perhaps of heparin as well, is largely due to suppression of aldosterone secretion.


Enzymes leading to mucopolysaccharide synthesis in granulation tissue.


Histochemical studies on the growing human tibial cartilage.


Silent period in patients with parkinsonian rigidity.


Histological characteristics of mesothelioma associated with asbestos.


Active transport and enzymes of the erythrocyte membrane under protein deprivation. 1. Starvation for 3 days causes membrane damage of the rat erythrocyte manifested by several alterations. The adenosine-triphosphatase activity is decreased but that of acetylcholinesterase is not affected. 2. The ouabain-sensitive adenosine-triphosphatase activity increases at the expense of the non-sensitive enzyme moiety. 3. The Rb(+) uptake is not altered but the galactose transport is accelerated by the stated experimental conditions. 4. The modifications induced by starvation do not recover on re-feeding.


Temperate phages influencing lipase production by Staphylococcus aureus.


Possible relationship between aortic acid mucopolysaccharides and species-susceptibility to experimental atherosclerosis.


Newer fibrinolytic agents.

Newer fibrinolytic agents.


Biochemical studies in Huntington's chorea. II. Composition of blood lipids.


1-Phosphofructokinase from an anaerobe.

1-Phosphofructokinase from an anaerobe.


The occurrence of gamma-aminobutyric acid in human tissues other than brain.


A peculiar mode of muscular innervation in Amphioxus. Light and electron microscopic studies of the so-called ventral roots.


In vitro susceptibility of UC-18 staphylococci.


Action of 5-fluorodeoxyuridine on human chromosomes.


Megaloblastic anaemia developing during treatment of epilepsy.


Mucopolysaccharides as a localized factor of egg-shell stability.


ATP-ase as inhibitor of lysokinase and plasminoplastin activators of fibrinolysis in vitro.


Sulphate conjugation during development, in human, rat and guinea pig.


Sulphate conjugation during pregnancy and under the influence of cortisone.


Compensable psychogenic backache.

Compensable psychogenic backache.


The effect of alum-precipitated pyridine ragweed extract on guinea pigs. II. Comparison of passive cutaneous anaphylaxis with Arthus reactivity after single low dose.


Clinical manifestations of strongyloidiasis.


The Brenner tumor.

The Brenner tumor.


Electrocardiogram of the month.

Electrocardiogram of the month.


The treatment of acne.

The treatment of acne.


Specific reaction of local anesthetics with phosphodiester groups.


7-alpha-hydroxylation of delta-5-pregnenolone and of its conjugates by rat-liver microsomes.


Does squinting matter?

Does squinting matter?


Schooling for the handicapped.

Schooling for the handicapped.


Studying 16,000 children.

Studying 16,000 children.


Research studies in physical fitness as applied to atypical youth.


Comparative responses of regulative and determinate embryos to metabolic inhibitors.


In vitro studies on 35S-sulfate incorporation into the acid mucopolysaccharides of chick embryo cardiac jelly.


Acid mucopolysaccharide content of the cardiac jelly of the chick embryo.


Gene and phenocopy: selection experiments and tests with 6-aminonicotinamide.


Differentiation of transplanted larval salivary glands of Drosophila hydei in adults of the same species.


"One's" therapy of seborrheic dermatitis.


Seborrheic dermatitis.

Seborrheic dermatitis.


Current topical therapy for acne vulgaris.


Fundamentals in acne management.

Fundamentals in acne management.


Current embryology and treatment of gastroschisis and omphalocele.


Correlation between staphylococcal serotypes with 263-1 factor and phage group 1.


Excitation-contraction coupling and control of cardiac contractility.


An attempt at biochemical characterisation of histologically well defined tumours.


Demonstration of intercoronary anastomoses in human hearts with a low viscosity perfusion mass.


Quantitative and qualitative cytochemical studies on the Amphiuma basophil leucocyte.


Stoichiometry of proton translocation through the respiratory chain and adenosine triphosphatase systems of rat liver mitochondria.


Case records of the Massachusetts General Hospital. Case 31-1966.


Assessment of disability.

Assessment of disability.


Compensation to nurse for herniated disk.


Cardiac impulse in hypertrophic obstructive cardiomyopathy.


The effect of bile salts on oxygen consumption, oxidative phosphorylation and ATP-ase activity of mucosal homogenates from rat jejunum and ileum.


An oral digit symbol test.

An oral digit symbol test.


The Knox cubes as a test of memory and intelligence with male adults.


Leukocyte alkaline phosphatase in mongolism.


Control of myocardial contraction: the sensitivity of cardiac actomyosin to calcium ion. The control by calcium ion of the adenosine triphosphatase activity of cardiac actomyosin is similar to that of white skeletal actomyosin. This finding indicates that the slower contraction and relaxation of heart muscle do not reflect different levels to which free calcium ion concentration around the myofibrils must be adjusted during contraction and relaxation and suggests a mechanism whereby myocardial contractility may be regulated.


Low back pain in men receiving workmen's compensation. In Ontario, only about 10% of compensation patients with low back pain are disabled more than six weeks and hence tend to have chronic complaints. Six hundred and twenty-three such patients were studied to determine the distribution of diagnoses and to test the effectiveness of various programs of conservative therapy.Two hundred and thirteen patients were assigned in rotation to one of four treatments. The results were inconclusive. In 70% of these, the pain was due to intervertebral disc degeneration with added trauma.Two hundred and sixteen patients were assigned randomly to a treatment involving mild exercise, or one with vigorous exercise. Neither was found to be superior. In 76% of these, the pain was due to disc degeneration with added trauma.Using 194 patients, the results of treatment in the Compensation Board Rehabilitation Centre were compared with those obtained by treatment at home. Satisfactory improvement was achieved in 15 of 95 treated at home, and in 42 of 99 in the Centre. The failure of treatment in six of each 10 cases indicates that present-day methods of management of such patients are unsatisfactory.


Role of the B-complex vitamins on intestinal activity in dogs.


1965 achievements of Workmen's Compensation Board reviewed.


Effect of vitamin A on mucopolysaccharides in myxovirus-infected cells.


Early developmental staging as a prophecy index in Down's syndrome.


Alzheimer's disease and senile dementia as seen in mongoloids: neuropathological observations.


Mosaicism in Down's syndrome: studies in a child with an unusual chromosome constitution.


Down's syndrome associated with family history of malignancy in mothers of affected children.


Reproductive performance of mothers of mongols.


The role of dental auxiliaries in child dental health.


Skin disease from colour developers.

Skin disease from colour developers.


Inhibition of cell division and cell elongation in higher plants by inhibitors of DNA synthesis.


The nature of inclusions in erythrocytes of turkeys treated with diethylstilbestrol.


Hepatitis attributed to sulfamethoxazole.


Myofibrillar adenosine triphosphatase activity of human heart tissue in congestive failure: effects of ouabain and calcium.


Diagnostic signs in compressive cardiac disorders. Constrictive pericarditis, pericardial effusion, and tamponade.


Inhibition of protein synthesis in cardiac hypertrophy and its relation to myocardial failure.


Studies on the fibrinolytic enzyme system in obesity. Plasma fibrinolytic activity, inhibitors of fibrinolysis, and fibrinogen were estimated in 34 subjects of varying ratio of observed to standard weight. The inverse relationship between fibrinolytic activity and the ratio of observed to standard weight was confirmed. No significant correlation was found between anti-plasmin or anti-urokinase and the ratio of observed to standard weight. It was therefore concluded that the decreased plasma fibrinolytic activity in obese subjects is due to decreased production of plasminogen activator rather than to excessive inhibition.


Combined hypertrophy.

Combined hypertrophy.


Exhaustion of atrial fibrillation in aneurysmatic dilatation of the left atrium.


Philosophy of operation and medical policy of the Meeting Street School.


Special education for handicapped children--where and when to use it.


Massive pulmonary embolism. VI. Prevention by partial occlusion of the inferior vena cava.


Antibody types in experimental animals and their biologic properties.


Histochemical studies on the red, white and intermediate muscle fibers of some skeletal muscles. I. Succinic dehydrogenase activity and physiological function of intercostal muscle fibers.


Histochemical studies on the red, white and intermediate muscle fibers of some skeletal mescles. II. The capillary distribution on three types of fibers of some skeletal muscles.


Electron microscopic studies on the tumor induced by adenovirus type 12.


Physical analysis of the energy transducing reaction in mitochondria.


Multiple keratoacanthomata. Response of a case to systemic chemotherapy.


A simple method for the determination of urinary dehydroepiandrosterone.


Determination of androsterone and dehydroepiandrosterone sulfates in human serum by gas-liquid chromatography.


Microbiological formation of 3-beta,7-alpha,15-alpha-trihydroxyandrost-5-en-17-one.


Chemotherapy studies in an animal tumor spectrum. II. Sensitivity of tumors to fourteen antitumor chemicals.


The enzymic oxidation of thiols.

The enzymic oxidation of thiols.


The uncoupling of respiratory-chain phosphorylation by 4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole. 1. 30mmum-4,5,6,7-Tetrachloro-2-trifluoromethylbenzimidazole (TTFB) uncouples respiratory-chain phosphorylation. The respiration rate of uncoupled mitochondria is significantly greater than the state 3 rate. Neither added orthophosphate nor ATP is required to sustain this rate. The oligomycin- and octylguanidine-induced inhibitions of respiration are relieved by uncoupling concentrations of TTFB. 2. Uncoupling concentrations of TTFB elicit a high adenosinetriphosphatase activity and inhibit the ATP-dependent succinate-linked reduction of NAD catalysed by submitochondrial particles from ox-heart mitochondria. 3. The action of TTFB is similar to that of 2,4-dinitrophenol. Evidence is presented which shows that it is the anionic forms of benzimidazoles and imidazoles, having the negative charge localized on the ring nitrogen atom, which are the effective uncoupling agents.


Pseudodisc--the problem of backache.

Pseudodisc--the problem of backache.


The effect of long-term ethionine treatment on the activity of the serum properdin in rats.


Effects of dinitrophenol and oligomycin on the coupling between anaerobic metabolism and anaerobic sodium transport by the isolated turtle bladder. Dinitrophenol (1 x 10(-5)M) has been found to inhibit anaerobic sodium transport by the isolated urinary bladder of the fresh water turtle. Concurrently, anaerobic glycolysis was stimulated markedly. However, tissue ATP levels diminished only modestly, remaining at approximately 75% of values observed under anaerobic conditions without DNP. The utilization of glucose (from endogenous glycogen) corresponded closely to that predicted from the molar quantities of lactate formed. Thus the glycolytic pathway was completed in the presence of DNP and if ATP were synthesized normally during glycolysis, synthesis should have been increased. On the other hand, the decrease in Na transport should have decreased ATP utilization. Oligomycin did not block sodium transport either aerobically or anaerobically, but ATP concentrations did decrease. When anaerobic glycolysis was blocked by iodoacetate, pyruvate did not sustain sodium transport thus suggesting that no electron acceptors were available in the system. Two explanations are entertained for the anaerobic effect of DNP: (a) Stimulation by DNP of plasma membrane as well as mitochondrial ATPase activity; (b) inhibition of a high energy intermediate derived from glycolytic ATP or from glycolysis per se. The arguments relevant to each possibility are presented in the text. Although definitive resolution is not possible, we believe that the data favor the hypothesis that there was a high energy intermediate in the anaerobic system and that this intermediate, rather than ATP, served as the immediate source of energy for the sodium pump.


Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.


Studies on the alteration of species-specific resistance by ethionine-induced inhibition of protein metabolism. 3. Infection experiments in rats with Teschen-disease virus.


Ganglioside inhibition of blood group antibodies with special reference to blood group I.


On measuring left ventricular volume.

On measuring left ventricular volume.


The allosteric nature of substrate inhibition of insect actomyosin ATPase in presence of magnesium.


Cardiac performance in heart-lung preparations of rats with experimental cardiac hypertrophy.


Plasma enzymes that release kinins.

Plasma enzymes that release kinins.


Camping though handicapped.

Camping though handicapped.


The haemophilic boy in school.

The haemophilic boy in school.


Unbinding the homebound.

Unbinding the homebound.


Influences of public health education.

Influences of public health education.


An improved method for the determination of orthophosphate suitable for assay of adenosine triphosphatase activity.


Controlled clinical trial of "Atromid" (androsterone with ethyl-p-chlorophenoxy-isobutyrate) and "Persantin" (dipyridamole) in cases of myocardial infarction.


Urological management of paraplegic patients.


The protein nutritive quality of ikan bilis (Stolephorus spp.).


A study of the haemolysin test in the identification of V. Cholerae biotype, El Tor.


A study of the psychosomatic aspects of peptic ulcer.


The life cycles of nematodes parasitic in man: an evolutionary sequence.


My aching back.

My aching back.


Evaluation of abdominal decompression during the first stage of labor.


Acid mucopolysaccharides and cirrhosis of the liver.


Studies on reticuloendothelial system and hematopoiesis. II. A study on the morphology and function of erythroblastic islet.


The roentgenographic features of the KS mucopolysaccharidosis of Morquio (Morquio-Brailsford's disease).


Effects of diazoxide administration on plasma glucose, insulin, and lipids in Von Gierke's disease.


Rehabilitative nursing.

Rehabilitative nursing.


Dressing activities for disabled persons.


Federally financed dental care; could Ohio dentists meet the challenge?


Prophylactic odontotomy: a review.

Prophylactic odontotomy: a review.


The enteric surface coat on cat intestinal microvilli. The enteric microvilli of the cat, bat, and man are coated with a conspicuous layer composed of fine filaments radiating from the outer dense leaflet of the plasma membrane. This surface coat is prominent on the absorptive cells but is not so thick on the goblet and undifferentiated crypt cells. In other species the surface coat is poorly developed or inconsistent, but all intestinal microvilli have traces of such a coating over the tips and sides of the microvilli. Tissues prepared by the ordinary sectioning techniques for electron microscopy usually reveal this component when stained with uranyl acetate followed by lead staining. The surface coat is intensely periodic acid-Schiff (PAS) positive and reacts with Alcian blue or Hale's colloidal iron stain for acid mucopolysaccharide. It is also stained by toluidine blue at low pH. Repeated washings or incubation with various chemical agents have failed to remove or markedly alter the appearance of the coating, but extruded cells undergoing autolysis lose their surface coats. The stability, consistent presence, and intimate association of the mucopolysaccharide coat suggest that it may be an integral part of the plasmalemma rather than an "extraneous coat."


Antibacterial management of infection due to gram-negative bacilli. 3. Use of ampicillin, the cephalosporins, spectinomycin, and chemotherapy.


Self-adaptive control and respiratory system.


Nicotinamide mononucleotide pyrophosphorylase activity in ascites cell extracts.


Incidence of disability in 1965.

Incidence of disability in 1965.


Congenital anomalies of the abdominal musculature and urogenital tract in a foal.


Skin eruption in a patient receiving hemineurine.


Sulfhydryl groups involved in the active site of myosin A adenosine triphosphatase. I. Specific blocking of the SH group responsible for the inhibitory phase in "B phasic response" of the catalytic activity.


Testimony of employer's doctor admissible in workmen's compensation case.


A medical history of poison ivy (Rhus toxicodendron).


Microscopic anatomy and histochemistry of glands in the external auditory meatus of the cat (Felis domesticus).


Thin-layer chromatography and the rapid identification of common acidic glycosaminoglycans.


Obesity and heart failure.

Obesity and heart failure.


Sequential experimentation and multivariate analysis in the evaluation of a treatment for postoperative intestinal symptoms.


The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinase. 1. A theoretical appraisal of the alternative pathway mechanism for a two-substrate enzyme shows that this mechanism is capable of giving rise to apparent substrate inhibition or substrate activation (Dalziel, 1958). It has now been shown that these phenomena may occur simultaneously in the following ways. With certain relationships between the kinetic parameters and the constant concentration of one substrate, A, the plot of initial rate, v, against the concentration of the other substrate, B, may show substrate ;activation' at low concentrations of B and substrate ;inhibition' at high concentrations of B. In other circumstances the plot of v against [B], with [A] constant, may be sigmoid (substrate activation), whereas the plot of v against [A], with [B] constant, may pass through a maximum (substrate inhibition). 2. Kinetic data for phosphofructokinase are of the latter type and it is suggested that the mechanism of this enzyme may involve a kinetically preferred pathway. It is emphasized that the phenomena of substrate inhibition and activation need not necessarily involve more than one binding site for each substrate on the enzyme molecule, nor more than one monomer per molecule.


Legal aspects of industrial immunization programs.


Referral to attorneys.

Referral to attorneys.


Audiological assessment of a mongoloid population.


Studies on progressive muscular dystrophy. I. Effects of adenosinetriphosphate and its related compounds on progressive muscular dystrophy.


Another cause of low back pain: lipomata in the sacroiliac region.


Fate of injected dehydroisoandrosterone, testosterone, and dehydroiisoandrosterone sulfate in plasma in the human.


Aryl and steroid sulfatase in the human ovary.


The stabilizing effect of neutral salts on plasmin.


A survey of Salmonella VI-phage types occurring in Federation of Malaya and Singapore.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1966.


Pyogenic abdominal wall and psoas abscesses in children.


Benzoyl peroxide and sulfur: foundation for acne management. One hundred and thirteen consecutive patients with acne were studied by qualified dermatologists during a trial of topical 10% benzoyl peroxide and 2%-5% sulfur cream. The results were considered "good" to "excellent" in both office and clinic situations. The method was remarkably free of undesirable side effects. The program has been adopted as a standard acne regimen at the dermatology clinic of the Royal Victoria Hospital, Montreal.


Applicability of exfolative vaginal cytology in sexual hormonology.


Changing concepts in obstetrics.

Changing concepts in obstetrics.


Comparative study of intrauterine contraceptive devices--spiral, loop, and ring.


Labor management with unlimited clean vaginal examinations; a review of 4,537 cases.


Sex health for college students.

Sex health for college students.


Safety evaluation of an acid powder for routine vaginal cleansing.


Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents.


Vectorcardiographic signs of biventricular hypertrophy.


Fractionation of urinary biocolloids in children and adults by gel filtration.


A lymphocytosis-stimulating  substance in Mongoloid plasma.


Effect of a subcurative dose of TWSb on the levels of phosphate esters in Schistosoma mansoni.


Adenosine-5'-sulfatopyrophosphate, an analogue of adenosine triphosphate. II. Interaction with myosin, actomyosin, and muscle fibers.


Mechanism of the Crabtree effect in yeast grown with different glucose concentrations.


Effect of alloxan on mitochondrial adenosinetriphosphatase activity and the ATP-ADP exchange reaction.


Introduction: mucopolysaccharides.

Introduction: mucopolysaccharides.


Effects of FUdR and thymidine on incorporation of deoxycytidine into DNA of Vicia faba.


Very high molecular weight mucopolysaccharides and mucopolysaccharide-protein complexes--how far can we extrapolate?


Oxidative phosphorylation accompanying oxidation of short-chain fatty acids by rat-liver mitochondria. 1. The factors concerned in the estimation of P/O ratios when fatty acids are oxidized by rat-liver mitochondria have been assessed. 2. The oxidation of butyrate, hexanoate and octanoate is accompanied by ATP synthesis. At low concentrations of the fatty acids, P/O ratios approximately 2.5 are obtained. 3. Oxidative phosphorylation is uncoupled, respiratory control ratios are lowered and respiration is inhibited when the concentration of the fatty acid in the incubating medium is raised (to 5-10mm); octanoate is a more potent uncoupler than either hexanoate or butyrate. 4. Serum albumin and carnitine, either singly or in combination, protect the mitochondria from the effect exerted by the fatty acids. 5. The rate of oxidation of short-chain fatty acids in the presence of ADP is increased in the presence of carnitine.


The early fate of autogenous grafts in the canine femoral vein.


The action of neutral hypochlorite on epithelial mucopolysaccharides. 1. The uptake of dilute neutral hypochlorite by epithelial mucopolysaccharides has been compared with that of proteins, polysaccharides, amino acids and sugars. The uptake has been shown to be related to the protein content of the mucopolysaccharides rather than their polysaccharide content. 2. The destruction of the components of epithelial mucopolysaccharides, certain sugars and polysaccharides after oxidation with dilute neutral hypochlorite at 0-4 degrees has been studied. Very little destruction of the sugar components occurred and in epithelial mucopolysaccharides the only amino acid destroyed specifically was arginine. 3. Oxidation of bovine submaxillary-gland mucoprotein and ovalbumin caused very little destruction of hexosamine and no detectable liberation of this residue as a free reducing group, indicating that the O-seryl galactosaminide and the N-acyl-glycosylamine linkages reported to be present in these compounds were relatively stable to hypochlorite. 4. Depolymerization of epithelial mucopolysaccharides by neutral hypochlorite has been studied by using gel-filtration columns and compared with the depolymerization of polysaccharides and proteins under similar conditions. The polysaccharides examined were relatively resistant to oxidation whereas the proteins were extensively broken down. It is inferred that the extensive depolymerization of epithelial mucopolysaccharides by hypochlorite is related to their protein content rather than their polysaccharide content. 5. Fractionation of the products of oxidation of epithelial mucopolysaccharides by column procedures has revealed that the relative proportions of components in all fractions were similar to those in the original material. 6. Though this study does not provide unequivocal evidence from which the overall structure of this type of epithelial mucopolysaccharide may be deduced, the balance of probabilities now appears to favour a long polypeptide chain to which a large number of oligosaccharide side chains are attached via O-seryl and O-threonyl glycosidic linkages. The results, however, are also consistent with an alternating sequence of short polysaccharide and polypeptide chains and further evidence is necessary before this structure can be ruled out.


The effect of fasting on esterification of palmitate by rat liver in vitro.


Virulence and the biochemical characters of staphylococci.


New, histological and biochemical, researches in experimentally induced arteriosclerosis.


On the pathomorphology of osteomyelosclerosis.


Histochemistry of lipid metabolism in the liver of rabbits treated with chlortetracycline (CTC).


The spread of non-tuberculous pulmonary diseases in Bulgaria.


Susceptibility of tubercle myobacteria to antibacterial drugs and its importance for the clinical course of tuberculosis.


The environment: its role in surgical infections.


Arteriography: an aid in the diagnosis of vascular disease.


Pregnancy and delivery following bilateral ureteral transplant to the bowl for exstrophy of the bladder. Report of a case.


Progress in earlier recognition of breast cancer.


Current acid-fast bacilli in Douglas County.


Neurologic manifestations of hyperpyrexia.


Voluntary service in child health and child care.


Facilities for the blind in Singapore.

Facilities for the blind in Singapore.


Intracellular autogenetic effects of muscular contration on extensor motoneurones. The silent period. 1. Intracellular records have been taken from cat motoneurones belonging to gastrocnemius and soleus or to popliteal synergists during contractions of gastrocnemius and soleus, acting separately or jointly. Such contractions were elicited by brief tetani or single shocks to the peripheral end of the cut ventral roots L7 or S1.2. Hyperpolarization of the motoneurone accompanies rise of tension in contraction. The amount of it increases when at constant extension the contraction of the muscle is increased by increasing stimulus strength, as well as when it is increased by augmenting extension at constant stimulus strength. It is therefore tension-sensitive.3. The duration of the hyperpolarization induced in this manner reflects the duration of the contraction itself, being considerably longer in the slow soleus than in the faster gastrocnemius. It is often preceded by a brief wavelet of depolarization ascribed to the so-called back-response.4. Early in relaxation there occurs a transient ;hump' of membrane depolarization. This corresponds to the moment characterized by phasic bursts from the spindle primaries. The ;hump' terminates hyperpolarization.5. When the cell is stimulated by injected current to maintained repetitive firing, the ;silent period' in contraction begins with the phase of hyperpolarization and ends with the hump of depolarization as described above.6. Later during relaxation, delayed inhibition, may or may not follow often accompanied by hyperpolarizing activation noise and sometimes also visible as an extension of the silent period of a firing cell. There is, however, no marked hyperpolarization of the motoneurone in delayed inhibition.7. In the Discussion the events described above are related to previous studies employing monosynaptic testing or electromyography for the analysis of the variations of excitability caused in extensor motoneurones by autogenetic contractions as well as to known properties of stretch receptors.


Systemic eczematous "contact-type" dermatitis medicamentosa.


Dichlorophene allergy.

Dichlorophene allergy.


Copper poisoning in the snail Helix pomatia and its effect on mucous secretion.


The anterior salivary gland of the octopus (Octopus vulgaris) and its mucous secretion.


The presence of mucopolysaccharides in the hepatopancreas of the isopod, Armadillidium vulgare.


Interagency coordination. A basic need in serving handicapped children.


Activation and inhibition of myosin B adenosine triphosphatase by mg++ and ca++ at low concentration of KC1.


Optical rotatory dispersion and enzymic studies on the tryptic digestion of rabbit skeletal and cardiac myosins and their macromolecular fragments.


Bound adenosine diphosphate and adenosine triphosphate in resting and contracting muscle.


Inhibition of proteolytic enzymes by beta-lipoprotein.


Histochemical investigations on the behaviour of some enzymes in liver cells of the mouse under the influence of oestrogens. I. Alkaline phosphatase (ALP-ase), adenosinetriphosphatase (ATP-ase), acid phosphatase (AP-ase).


Repair of defects after partial resection of the abdominal wall.


Effects of MgEDTA on the mucopolysaccharide metabolism in the atherosclerotic aorta.


Adenosine triphosphatase activity of adrenal medulla catecholamine granules.


Accumulation of Ca2+ and Sr2+ by rat-liver mitochondria: preferential loss of the adenosine triphosphate-dependent mechanism for Sr2+ accumulation.


The right ventricle and pulmonary vascular obstruction in bronchitis with emphysema.


Cytochemical observations on chick liver cell cultures infected with Trichomonas vaginalis. 1. Nucleic acids, polysaccharides, lipids, and proteins.


The electrocardiogram in chronic bronchitis and emphysema.


Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. 1. Androgenic secretion as demonstrated by a bioindicator method.


Psychological correlates of the MFS rehabilitation rating scale.


Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. II. Secretion of androgenic hormone in adrenals and testes during early stages of development.


The occurrence of relaxing granules in the muscle of the locust, Locust migratoria.


Anticoccidial activity of nicotinamide antagonists.


The occurrence and mechanism of P-wave inversion in lead I in right atrial overloading. Report of two cases.


Cardiomegaly in myxedema. Report of a case and review of the literature.


Infant and child mortality in Burma by ethnic group.


Correlative study between electrocardiographic findings and ventricular wall thickness based on cardio-synchronous angiocardiography. I. Comparison of angiocardiographic and postmortem thickness of ventricular wall in normal dogs.


Norepinephrine metabolism in hypertrophied rat hearts.


Effect of carcinolipin on the adenosine triphosphatase activity of isolated cellular fractions.


Delineating the possible for the multi-handicapped child with visual impairment.


Hormonal regulation of cardiac muscle citrate.


Studies on vaccination against cholera. 3. Immune response in man.


Heart size in pregnancy.

Heart size in pregnancy.


Mycologic testing of soil samples from populated areas with endemic nephropathy.


On some metabolic and functional changes of the heart muscle in experimental myocarditis.


Inquiries into the protein composition of the heart muscle in experimental myocarditis of dogs.


Intraparenchymal distribution of the blood vessels of the thyroid gland.


Early results of antibacterial treatment of newly traced consumptive patients.


The use of mathematical model in the study of the properties of the full-surface electrocardiogram. I: Scher generators in a homogeneous torso. II: "Enlarged heart" potentials.


Degradation of mucopolysaccharides by hepatic lysosomes.


Gas-liquid chromatographic separation of C19 and C21 human urinary steroids by a new procedure.


O-t-c anti-acne aids.

O-t-c anti-acne aids.


Inhibition by ergotamine and ergobasinine of Ca2+ uptake from the sarcotubular system.


The thymus and the tolerance function.

The thymus and the tolerance function.


Changes in biochemical properties of isolated human skeletal myofibrils with age and in Myasthenia gravis.


Studies on erythrocyte glycolysis. II. Free energy changes and rate limitings steps in erythrocyte glycolysis.


Studies on erythrocyte glycolysis. 3. The effects of active cation transport, pH and inorganic phosphate concentration on erythrocyte glycolysis.


Superprecipitation of actomyosin reconstructed with F-actin and NEM-modified myosin.


Two-year pedodontic internship residency program is approved.


Pedodontics at Harvard.

Pedodontics at Harvard.


Dental plan for children urged by professor.


The forgotten 3 per cent in the dental office--care of the mentally retarded.


A Head Start to where?

A Head Start to where?


Camping with the chronic sick.

Camping with the chronic sick.


Prosthetic service for pre school children.


Dentistry and the handicapped child.

Dentistry and the handicapped child.


Morphological and histochemical studies of partially and totally deafferented spinal cord segments.


"Fear and anxiety in the dental chair".

"Fear and anxiety in the dental chair".


Water fluoridation--its effect on pedodontics.


The periodic synthesis of thymidine kinase in mouse fibroblasts.


Further observations on the physiology and pharmacology of elasmobranch ventricular fluid.


Studies on sodium-potassium-activated adenosinetriphosphatase. XV. The rectal gland of the elasmobranchs.


A dental care plan for Michigan children.


Key figures in legislation for the handicapped.


PRESCAD--what is it?

PRESCAD--what is it?


Abnormal response to anaesthesia in a case of Huntington's chorea.


Mongolism, leukemia and sex chromatin anomalies.


The fibrinolytic enzyme system in physiological pregnancies at term and during labour.


Studies on hyaine membrane disease.3. Thrapeutic trial of urokinase-activated huma plasmin.


Angiocardiographic determination of the size of the left ventricle in congenital heart disease.


Painless chronic dissecting aneurysm of the aorta. Report of a case.


The pre-steady state of the myosin--adenosine triphosphate system. IV. Liberation of ADP from the myosin--ATP system and effects of modifiers on the phosphorylation of myosin.


The adenosine diphosphate--adenosine triposphate-excange reaction of cerebral microsomes and its relation to he sodium ion-stimulatd adenosine-triphosphatase reaction. Microsomes from guinea-pig cerebral cortex contain a system capable of exchanging ADP with ATP at rates of about 20mumoles/mg. of protein/hr. The ADP-ATP-exchange reaction requires Mg(2+) for activity. The reaction is not stimulated by Na(+) or K(+) and is not inhibited by ouabain, in contrast with the Na(+)-plus-K(+)-stimulated adenosine triphosphatase. The pH optimum also differs from that of the adenosine triphosphatase. The ADP-ATP-exchange reaction is stimulated two- to three-fold by non-ionic, anionic and cationic detergents, even when these agents are inhibiting the adenosine-triphosphatase reaction. This reaction may represent a component of the Na(+)-plus-K(+)-stimulated adenosine-triphosphatase reaction but is more likely to be due to other enzyme systems present in microsomal subfractions.


Calcium-dependent granular adenosinetriphosphatase from glycerinated myofibrils.


Role of ADP bound to F-actin in superprecipitation and enzymatic activity of actomyosin.


Inhibition of gastric secretion by fractionated lymph. Elaboration of gastrone-like substance during digestive phases in dogs.


An antithrombin (maculatin) and a plasminogen activator extractable from the blood-sucking hemipteran, Eutriatoma maculatus.


Studies of erythrocyte spicule formation in haemolytic anaemia.


Endotoxin shock in the New Zealand white rabbit. An evaluation of fibrinolysin therapy.


On some functional and histochemical changes in myocarditis of rabbits induced by streptolysine and A-group streptococci.


Meiosis in trisomic Down's syndrome.

Meiosis in trisomic Down's syndrome.


Hygienic and experimental studies of the conditions of work and occupational morbidity in electric and gas welders.


Intrapericardial fat pads and anomalous development of the septum transversum as a cause of pseudocardiomegaly.


Luetic aneurysms of the aortic valve, sinus of Valsalva, and aorta.


Experimental retinal vein occlusion and treatment with fibrinolysin.


Studies in sickle cell anemia. XXVII. Complications in infants and children in the United States.


Rehabilitation of the injured worker.

Rehabilitation of the injured worker.


Effect of hypertrophy on myocardial distensibility.


Chromosomes of "mongoloid" hamsters.

Chromosomes of "mongoloid" hamsters.


Psychosomatic aspects of acne: a controlled study.


Estimation of dehydroepiandrosterone sulfate in human serum by gas-liquid chromatography.


Estimation of trypsin in presence of plasmin and their separation by gel filtration.


Effects of zinc on adenosine triphosphatase activity and superprecipitation of actomyosin from skeletal muscle of rabbit.


Stimulation of Na+ and K+ dependent adenosine triphosphatase by ouabain.


Effects of preparations of heparin and heparitin sulfate on fibrinolysis.


Immunology and cancer.

Immunology and cancer.


Psychologic aspect of ulcerative colitis in children.


Metabolic and statural response to human growth hormone in juvenile Cushing's syndrome with dwarfism.


Recent advances in treatment of the eye.


Controlled relaxation. I. Quantitation of electromyogram with abdominal relaxation.


The "butterfly" eruption.

The "butterfly" eruption.


Dilatation of the heart.

Dilatation of the heart.


Leftward shift of the terminal P forces in the ECG associated with left atrial enlargement.


Clinical pathologic conference.

Clinical pathologic conference.


The action of ketonic prostaglandins on the guinea-pig myometrium. 1. Prostaglandin E(1) or E(2) has two clearly distinguishable effects on the guinea-pig myometrium in vitro.2. The first of these, the ;direct' effect, is manifested by contraction accompanied by spiking, is readily modified by changes in the concentrations of Mg(2+), Ca(2+) and K(+) in the suspension medium, and does not long outlast the presence of the prostaglandin in the organ-bath. In this respect it resembles the responses to other stimulants.3. The second effect is manifested by ;enhancement' of the responses to non-specific stimulation, whether this be by chemical or electrical means. Enhancement may be demonstrated for up to 20-80 min after the PGE(1) or PGE(2) has been washed out of the organ-bath, and during this time the myometrium shows no consistent changes in electrical activity or in resting mechanical tension that may be associated with the enhancement effect. Enhancement following PGEs is not readily affected by moderate changes in the Mg(2+), Ca(2+) or K(+) concentrations of the suspension medium, and in all these respects it differs markedly from the effects of other stimulants.4. K(+)-depolarized myometrial preparations show feeble direct responses to PGEs, like those to other stimulants. They also show post-PGE enhancement of the responses to other stimulants, but not of the responses to electric field stimulation.5. The empirical method used for measuring the enhancement effect is examined critically.6. The possible mechanisms of the direct and enhancement effects are discussed. It is postulated that they involve actions at two different sites, which may be on two different types of cell but are more likely to co-exist on the same cells. The direct effect is postulated to result from depolarization at the exposed cell membrane, whereas enhancement may result from facilitation of excitation-contraction coupling.


Topical corticosteroids for skin disorders.


The reflex response to sinusoidal stretching of soleus in the decerebrate cat. 1. Soleus muscle in the decerebrate cat was stretched sinusoidally through various distances, at various frequencies while tension and e.m.g. activity were recorded.2. Two patterns of stretch reflex activity were seen. In one, slow stretching led to a large increase in tension, whereas in the other tension increased little during slow stretching, but rose steeply during a more rapid stretch. Intermediate states were also seen.3. Both these reflex patterns were abolished when the fusimotor fibres were blocked with Xylocaine.4. At low frequencies of stretching the e.m.g. activity was greatest at peak muscle length; at higher frequencies the greatest activity was found during lengthening. This angular advance of e.m.g. activity on length was greatest at 3.3-5 c/s. At the higher frequencies the e.m.g. activity was less in advance of muscle length.5. Angular advance of e.m.g. activity was greatest in the preparations that were also the most sensitive to slow stretching.6. Muscle contraction follows an electrical stimulus with a small delay. The delay between the end of stimulation and the end of muscle relaxation is longer, and may exceed 200 msec in cat soleus.7. The timing of the reflex tension during sinusoidal stretching depended on how far the angular advance of the e.m.g. combined with the damping properties of muscle offset the time delays in the reflex pathway.8. Changes in muscle tension generally preceded changes in muscle length. When, however, stretch amplitudes of 1 mm (peak to peak) were used, a phase delay of tension was sometimes seen. This only occurred in preparations that also showed little sensitivity to slow stretching.9. Phase delay of tension was usually found with frequencies of approximately 6-8 c/s, and this corresponds to the clonus frequency for soleus.10. The mechanisms of the two types of reflex behaviour, and the damping properties of the system are discussed.


Organization of neurones in the cat cerebral cortex that are influenced from group I muscle afferents. 1. Neurones in the Group I projection area of the first sensori-motor cortex were investigated with extra- and intracellular technique.2. The majority of the neurones influenced by volleys in Group I afferents of contralateral forelimb nerves received exclusively excitation, but some received exclusively inhibition, and some mixed excitation and inhibition.3. The Group I influenced cells were usually found 500-1500 mu beneath the cortical surface.4. The EPSPs and IPSPs evoked from Group I afferents had a steep rising phase and a slow, approximately exponential decay. The duration was sometimes more than 50 msec. The EPSP evoked by a maximal Group I volley was often formed by a small number of large unitary EPSPs.5. Latency measurements indicate that the majority of the Group I activated neurones were monosynaptically excited from the thalamic fibres, and hence constitute the fourth-order neurones in the Group I projection system. The latencies of the IPSPs suggest a disynaptic linkage with thalamic fibres. Hence, the exclusively inhibited cells would constitute fifth-order neurones. It is suggested that most or all of the fourth-order neurones are inhibitory.6. The convergence of excitation and/or inhibition to individual cells was usually extensive and included effects not only from muscle groups working at different joints but also effects from antagonistic groups at the same joint. In addition cutaneous afferents contributed synaptic actions which had a longer latency than the synaptic actions from Group I afferents.7. The neurones influenced from Group I afferents were not antidromically activated on stimulation of the pyramidal tract.


Congenital heart disease and pheochromocytoma.


Paternal transmission of a D/G translocation of Down's syndrome.


Anodontia in mongolism.

Anodontia in mongolism.


Differential diagnosis of visceral from somatic back pain.


The action of cytostatic agents on the chromosomes of human leukocytes in vitro (preliminary communication).


Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. I. An associated sodium-activated transphosphorylation.


Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. II. Effects of N-ethylmaleimide and other sulfhydryl reagents.


Change in platelet antiplasm in activity following splenectomy.


Development of the steady potential of the brain of chick embryos.


Comparative pathophysiology of the paroxysmal electroencephalogram. Paroxysmal electroencephalogram (spike and wave activity) in the lizard (Lacerta agilis).


Developmental changes in the protein composition of heart muscle in the rat.


Adaptation of rats of different ages to forced intake of a 2 per cent NaC1 solution without the occurrence of salt hypertension.


The incorporation of S35 methionine into proteins of denervated and reinnervated muscle.


Optimum conditions for studying autoiodoproteolysis of 127-I-thyroglobulin in rats.


Changes in the protein content of plasma during blood losses in rats.


Changes in haemoglobin fractions separated on CM-sephadex in normal newborn rats and in newborn rats after repeated blood losses.


Studies on the glycoproteins of human seminal plasma.


Changes in the membrane potential of cortical cells during spreading depression.


Decerebrate control of primary afferent depolarisation evoked by adequate stimulation of cutaneous receptors.


The effect of thalamic spreading depression on electric activity in the caudate nucleus and the hippocampus in rats.


Optic evoked potentials in children, using different stimulation frequencies.