Study of spontaneous resistance to histamine in guinea pigs.


Urinary catecholamines and metabolites in renal hypertensive dogs.


Amnion autografts and allografts as a cover for skin defects in sheep. A preliminary report.


Serum and urinary lysozyme in leukaemia and polycythaemia vera.


Pyridoxine-responsive anemia. A preleukemic manifestation?


Massive preoperative radiation therapy in the treatment of osteogenic sarcoma.


The significance of bone marrow morphology for the diagnosis of polycythaemia vera.


Distinctions between idiopathic ineffective erythropoiesis and di Guglielmo's disease: clinical and biochemical differences.


Short courses of cytosine arabinoside and L-asparaginase in children with acute leukemia.


Ultrastructural studies on the acute leukemic myeloblast.


Treatment of acute leukemia in children.


On the chemical nature of basophilic (mucoid) degeneration of myocardium.


Fibrinolysis and haemostasis.

Fibrinolysis and haemostasis.


Bone marrow necrosis. A study of seventy cases.


Echocardiography in left atrial myxoma: relation to the findings in mitral stenosis.


Traumatic haemolysis after heart valve replacement: a comparison of haematological investigations.


The clinical synopsis.

The clinical synopsis.


Endocardial pacing in heart block due to acute myocardial infarction.


Involvement of the skin and subcutaneous tissue in azotaemic hyperparathyroidism.


The kinetics of 5-fluorocytosine elimination in man.


Pulmonary function in alpha 1 -antitrypsin deficiency.


The regulation of pH in the body and in society a parable of the proton.


A renin-secreting renal tumour associated with hypertension.


Acute disseminated intravascular coagulation in systemic lupus erythematosus.


N-butyl cyanoacrylate as a pulp capping agent.


The effect of a calcium hydroxide-water paste on micro-organisms in carious dentine.


Setting characteristics of lining and cementing materials.


Relative analgesia. An introductory note.


Treatment of the mentally handicapped. A general dental practitioner's experience.


Impression materials as foreign bodies.

Impression materials as foreign bodies.


Roughness discrimination in cats with dorsal column lesions.


A system for continuous measurement of gas exchange and respiratory functions.


A study of indigenously produced heat curing and auto-polymerizing acrylic resins.


DNA synthesis in normal and leucemic cells as related to therapy with cytotoxic drugs.


Relationship of intercanine distance with the distance between the alae of nose.


Comparative use of alcohol and chlorpromazine by experimentally stressed CF-1 mice.


Flucytosine therapy in cryptococcosis. Report of a case.


Hodgkin's disease terminating in acute erythromyeloblastic leukemia with diabetes insipidus. A case report and review.


Ulcerative disease of the colon proximal to a benign neoplasm.


Cardiac tamponade and constrictive pericarditis.


Radionuclide angiocardiography.

Radionuclide angiocardiography.


The physician as witness the problem of dying declarations.


An electron microscopic study of tetracycline-induced enamel defects in rat incisor enamel.


Osteogenesis in the basioccipital bone of the Wistar albino rat.


Location and first appearance of rat incisor pigmentation.


The load dependence in micro indentation hardness testing of enamel and dentin.


Exudation and leukocyte emigration in progesterone and estrogen treated rats. The influence of an altered level of female sex hormones in rats on the inflammatory reaction provoked by factors in human dental plaque was studied at the University of Gothenberg.  40 oophorectomized female rats were used.  The 4 groups (10 rats in each) were adminstered injections of progesterone, estrogen, progesterone and estrogen, and oleum arachidis, the vehicle of the hormone preparations, respectively, for 19 days.  On the fourth day of injection, 4 perforated, cylindrical Teflon wound chambers were placed subcutaneously in the back of each rat.  By the nineteenth day a richly vascularized granulation tissue had formed around each chamber and within the perforations of each chamber wall.  On that day plaque filtrate was injected into 2 chambers in each rat.  Exudates were aspirated, and the effects of plaque filtrate injection on volume of wound fluid and mean number of leukocytes/exudate were determined.  In all groups significantly more (p less than .001) exudate was retained during a 5-hour period following plaque filtrate injection than during a 5-hour period following saline deposition.  The chambers injected with plaque filtrate also had a significantly higher (p less than .001) concentration of leukocytes than the saline-injected chambers.  The development of acute inflammation through mechanical irritation and plaque filtrate injection was markedly enhanced in the progesterone-treated animals.  Estrogen had no effect, while combined progesterone and estrogen showed some effect.


The prenatal effects of maternal vitamin A deficiency on the cranial and dental development of the progeny.


Pitfalls of the Crozat appliance.

Pitfalls of the Crozat appliance.


A remedial program for tongue-thrust.

A remedial program for tongue-thrust.


The impact of interproximal band thickness on treatment and retention.


High-pull headgear versus cervical traction: a cephalometric comparison.


The long-range study committee: a new venture.


Interceptive orthodontics: indications and limitations.


Letter to the editor. Effect of molecular genetics and genetic engineering on the practice of orthodontics.


Mandibular growth and facial height changes in twins.


The influence of maximum perioral and tongue force on the incisor teeth.


The male adolescent facial growth spurt: its prediction and relation to skeletal maturation.


Inheritance of craniofacial morphology.

Inheritance of craniofacial morphology.


Gingival condition associated with orthodontic treatment. II. Histologic findings.


Elongation of the cranial base in girls during pubescence.


A principle of arcial growth of the mandible.


Longitudinal study of dental arch widths at four stages of dentition.


The ability of zinc phosphate and hydro phosphate cements to seal band spaces.


Orthodontics, bacteremia, and the heart damaged patient.


Adverse reactions to local anaesthetic-vasoconstrictor preparations. A study of the cardiovascular responses to Xylestesin and Hostacain-with-Noradrenaline.


Extra-oral anchorage for upper removable orthodontic appliances.


Calcifying odontogenic cyst. A case report.


A post crown for molars with divergent roots.


Interpretation of cyclic leukocytosis.

Interpretation of cyclic leukocytosis.


Specific conformations and interactions in chicken erythrocyte histone F2C.


High capacity chemisorbents for protein immobilization.


Availability of label in  3 H-thymidine for DNA synthesis in cultured macrophages.


C-4 pathway in Pennisetum purpureum.

C-4 pathway in Pennisetum purpureum.


Failure of immunological memory in DMBA-treated mice.


Genetic association between H-2 gene and testosterone metabolism in mice.


Alterations of adrenal cortex and thyroid in mice with congenital absence of the thymus.


The dean talks to the bulletin.

The dean talks to the bulletin.


Transneuronal degeneration as basic mechanism of muscular atrophy of central origin.


Diffusible fraction of serum cholesterol and atherogenesis.


Some public-health aspects of research in mental retardation.


Treatment of fractured or avulsed anterior teeth.


Fetal malnutrition--a problem of parental detection.


V.D. education in Nova Scotia high schools.


The doctor and his leisure: writing as a hobby.


Differential diagnosis of papilloedema by means of fluorescent angiography.


An epidemiological study of retinoblastoma in New Zealand.


Photocoagulation of retinal vascular disease.


A case of glaucoma.

A case of glaucoma.


Inflammatory pseudo-tumour of the orbit.


Soft lenses.

Soft lenses.


South Pacific fundus.

South Pacific fundus.


A disease index for ophthalmic practice.


The ophthalmologist and the community.

The ophthalmologist and the community.


Emergencies during anaesthesia.

Emergencies during anaesthesia.


Inflammatory reaction evoked by zinc polyacrylate and zinc eugenate cements. A comparison.


Gold-amalgam galvanic cells. The measurement of corrosion currents.


An emergency drug cabinet for use in general dental practice.


Quick-release locking plates.

Quick-release locking plates.


Emergency dental service in Medway towns.


Gramicidin S synthetase, an enzyme with an unusually large number of catalytic functions.


Far-infrared bands of amino-acid residues with -helical and -form conformations.


I-DNA suppressed by ethidium bromide and accumulated with dactinomycin.


Linear intermediates in the replication of adenovirus DNA.


Human anti-CEA antibodies detected by radioimmunoelectrophoresis.


Effect of trypsin on cell volume and mass.


Effect of non-narcotic analgesics on membrane permeability of molluscan neurones.


Handling properties of a capsulated spherical particle amalgam. An investigation.


Assessment of the medical status of patients in general dental practice. A comparative survey of a questionnaire and verbal inquiry.


Burkitt's lymphoma. A case in Ireland.

Burkitt's lymphoma. A case in Ireland.


Supernumerary molar teeth. A case report.


A practical guide to assisted operating. 1. Principles of assisted operating.


Biological control of dental disease? A personal view.


The Dental School of the University of Bergen.


Prevention in oral surgery.

Prevention in oral surgery.


Snowmobile injuries and the oral surgeon: survey of snowmobile injuries in central Wisconsin.


The short lingual cut in the sagittal osteotomy.


Prevention and treatment of postoperative pulmonary complications.


Spontaneous healing of a large osteomyelitic defect in the mandible: report of case.


Arthroplasty for bilateral temporomandibular joint ankylosis: report of case.


Submental herniation of sublingual gland: report of case.


Cherubism: report of case.

Cherubism: report of case.


Sialolithiasis of accessory salivary glands: review of 55 cases.


Inhalation of a tooth during maxillofacial injury: report of case.


Solitary myeloma with multiple mandibular lesions: report of case.


Diplopia as a sign of basal skull fracture accompanying a fractured mandible: report of case.


Iatrogenic fracture of the coronoid process: report of case.


Nevoid basal cell carcinoma syndrome: report of case.


Keratocysts of the jaws.

Keratocysts of the jaws.


Congenital unilateral facial hypoplasia associated with dental abnormalities. A case report.


The success rate of anterior crowns.

The success rate of anterior crowns.


Education for general dental practice.

Education for general dental practice.


Proposals for planned change in dental education and practice.


Complete denture construction in dental schools and hospitals of the United Kingdom and Ireland. A survey.


Answer cards. An aid to continuous assessment.


The organisation of joint research projects.


Bristol University Dental Expo'.

Bristol University Dental Expo'.


Teaching departments of community dentistry in the United States of America.


Phosphorus necrosis of the jaw: 'phossy jaw'.


On the loss-of-control phenomenon in alcoholism.


Alcohol consumption and arcus senilis: a search for a significant relationship.


Operant behavior of a chronic alcoholic under fixed ratio and fixed interval schedules of reinforcement using alcohol as a reinforcer.


Alcoholism in industry (U.S.A.).

Alcoholism in industry (U.S.A.).


Drug and alcohol use by young people attending a psychiatric emergency service.


Attitudes towards drug and alcohol addiction: patients and staff.


The social and psychological background of young drug abusers in Dublin.


Drug dependence in psychiatric admissions.


Drugs and their abuse: age groups particularly 'at risk'.


Changes in personality response ratings induced by smoking marihuana.


Psychosis associated with cannabis smoking.


Pyrexia with cytosine arabinoside.

Pyrexia with cytosine arabinoside.


The hazard to the dentist and his staff from dental radiology.


A patient with multiple conical teeth.

A patient with multiple conical teeth.


Self-inflicted gingival injuries. Gingivitis artefacta, factitial gingivitis.


Dentition and nutrition.

Dentition and nutrition.


An improved design of cheek retractor.

An improved design of cheek retractor.


A dental survey of people living in residential homes for the elderly in Cardiff.


Cavernous haemangioma of the cheek.

Cavernous haemangioma of the cheek.


The mechanics of the apron-spring removable orthodontic appliance.


Letter to the editor: licensure and dentistry.


The ecological dentist: a concept for reaching the masses.


Technician scholarship program--AFDE looks back and ahead.


Meharry implements new dental education concepts.


A profession cares for its own: the ADA relief fund.


Laser inhibition of dental caries suggested by first tests in vivo.


Reduction of x-ray dose by variable rectangular collimation and reflex optical direction of dental x-ray beams and by the supine position of the patient.


Leukoedema of the oral mucosa.

Leukoedema of the oral mucosa.


Identification of US Air Force lost in action personnel.


Epidermolysis bullosa dystrophica: report of two cases.


Emergency endodontic therapy: report of case.


Survey of the dental laboratory industry, 1971. IV. Summary and comparison with earlier surveys. Bureau of Economic Research and Statistics.


SMILE composite restorative material classified as provisionally acceptable. Council on Dental Materials and Devices.


Supplement of the list of certified dental materials. Council on Dental Materials and Devices.


Re-orientation about dental manpower concepts.


Training for careers in dental research.


Dental licensure reciprocity.

Dental licensure reciprocity.


Dental services in Indonesia.

Dental services in Indonesia.


Mechanism and control of initiation in the translation of R17 RNA.


Mammalian metaphase chromosomes with high molecular weight DNA isolated at pH 10.5.


Synaptosome antisera affect permeability of synaptosomal membranes in vitro.


Synthesis of human growth hormone fragments with growth-promoting activity.


Function of catecholamine-containing neurones in mammalian central nervous system.


Prolactin release induced by prostaglandin F2  in pregnant rats.


Electroviscous effect in dextran-erythrocyte suspensions.


New type of colony-forming cell located in the pleural cavity.


A rejuvenated hope--The New York Dental Service Corporation.


Blood concentrations of adrenaline in dogs after intravenous administration of 5-hydroxytryptamine.


Dental education.

Dental education.


An up-date on franchised dental practices, denturists, and the ADA Relief Fund.


A need for all views within the dental profession.


Lipoma of the tongue. Case report.

Lipoma of the tongue. Case report.


Supernumerary mandibular bicuspid. Report of a case.


Drug dependence in Glasgow 1960-1970.

Drug dependence in Glasgow 1960-1970.


Amphetamine abuse and government legislation.


The use of heroin and methadone by injection in a new town. Progress report.


The compulsory treatment of narcotic addicts.


Personal observations and impressions on treatment of drug dependency in treatment centres, in-patient units and prisons in the London area.


The role of the voluntary agencies in the various aspects of prevention and rehabilitation of drug abusers.


Treatment of drug addiction: past myths and present problems.


Treatment of drug addiction. Comments.

Treatment of drug addiction. Comments.


Treatment of drug addiction. Afterword.

Treatment of drug addiction. Afterword.


Hereditary inflammatory vasculitis with persistent nodules. A genetically-determined new entity probably related to lupus erythematosus.


Adult acid maltase deficiency. Abnormalities in fibroblasts cultured from patients.


Preferential sensitization of hypoxic cells to radiation in vivo.


Cell density and cell division in the early morphogenesis of the chick wing.


Isozyme specificity to temperature.

Isozyme specificity to temperature.


Accessibility of calcium ions to anionic sites of lipid monolayers.


Persistence of functional chloroplasts in Elysia viridis (Opisthobranchia, Sacoglossa).


Abolition of percentage requirement for accreditation of hospitals. Et tu Brute.


The autopsy--the key to quality control in medical care.


Nasotracheal intubation in infants and children.


Extensive urologic surgery without blood transfusion.


Nonfunctioning kidney.

Nonfunctioning kidney.


Pharmaceutical research.

Pharmaceutical research.


Hemangiopericytoma of central nervous system.


Improvement of medical literature. From the point of view of the author.


Meningioma coexisting with severe hypertension. Problems of diagnosis.


The d.a. Appearances.

The d.a. Appearances.


The people axiom.

The people axiom.


Whatever happened to money?

Whatever happened to money?


Ultraviolet autofluorescence: an aid in oral diagnosis.


New instrument detects jaw malfunction.

New instrument detects jaw malfunction.


Orofacial infections and their management.


Project concern.

Project concern.


A look at the ADA.

A look at the ADA.


National dental health survey of school population in Singapore dental caries.


Some medical conditions in relation to dentistry.


The encouragement of root- end closure in traumatised non-vital young permanent teeth.


A team approach to medical history.

A team approach to medical history.


Oral carcinoma in the fourth decade of life.


A post crown technique.

A post crown technique.


Deviation of the mandible corrected by an acrylic training flange.


Hints from an orthodontist.

Hints from an orthodontist.


Cutting your convention costs.

Cutting your convention costs.


The prevalance of dens invaginatus in maxillary incisors.


Social security: bigger, better...more expensive.


Bridging the generation gap in prevention.


Biting the hand.

Biting the hand.


REITs: right investment for you?

REITs: right investment for you?


Answering mother's questions.

Answering mother's questions.


Marginal leakage of a new restorative material--TD 71.


Helpful hints for aspiring authors.

Helpful hints for aspiring authors.


Acute necrotising ulcerative gingivitis.


The traumatic neurome--a review and case report.


Disorders of the temporomandibular joint and their management.


A cross-sectional study of the growth of the temporalis and masseter muscles.


Bell's palsy.

Bell's palsy.


Approach to the patient as a human being in dental practice.


Witsco dental clinic--a student community project.


Decision making in common denture complaints.


No more cavities.

No more cavities.


Stress and aphthous ulcers.

Stress and aphthous ulcers.


Simplifying the posterior composite resin restoration.


Condenser selection for pure gold compaction.


Medical emergencies and a standardized emergency kit for the dental office.


What are you operative dentistry and why are they saying all those nasty things about you?


Protection of lingual soft tissue when using a cervical rubber dam clamp.


Comparison of various maxillary Class 3 direct gold cavity designs.


Introduction to the universal light arch technique.


Truth in lending.

Truth in lending.


Begg stage 3--a suggestion.

Begg stage 3--a suggestion.


Dental photography: some new benefits.

Dental photography: some new benefits.


Photocopy to protect and audit accounts receivable.


Mini-impactions.

Mini-impactions.


Radiographic technic in the contour dental chair.


Reactions of stannous fluoride with powdered enamel and dentin.


Individualizing instruction in dental hygiene at the University of Hawaii.


The dentist in modern fiction.

The dentist in modern fiction.


Dentistry and the aging.

Dentistry and the aging.


The Mickey Mouse suitcase: a novel dental health education device for children.


[A principle of positioning cephalometric landmarks].


[The determination of nitrite in human whole saliva].


A comparison of the isoenzymic patterns of urinary ribonucleases in healthy subjects and patients with chronic granulocytic leukemia.


The motivation of employees in the dental office.


The significance of physical diagnosis, patient history, data, and medical screening in the dental office.


The temporomandibular joint pain dysfunction syndrome.


Alzheimer's disease: a review of recent studies.


X-ray films of the month.

X-ray films of the month.


The colostomy rehabilitation program.

The colostomy rehabilitation program.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 47-1972. A 65-year-old woman was admitted to the hospital because of dyspnea.  15 years previously biopsy of an enlarged left cervical lymph node revealed giant-follicle lymphoma; the patient received radiation.  7 years before a right radical mastectomy was performed for an adenocarcinoma of the breast; there were metastases to several anxillary lymph nodes.  4 years before, a malignant lymphoma was discovered again and radiation successfully given.  5 months before admission there was an onset of severe dyspnea.  Upon admission, the temperature was 36.9 degrees C, pulse 100, and respirations 32.  Blood pressure was 120/70.  Oxygen, prednisone, furosemide, chlordiazepoxide, and morphine were administered.  The woman died the 2nd day.  Clinical diagnoses showed that the woman died of carcinoma of the breast with metastoses to mediastinal lymph nodes, the chest wall and the lungs, and that lymphoma was inactive.  Radiation may have caused the late malignant tumor.  A late radiation-induced complication may be another malignant tumor.  It is noted that radiation therapy may be a calculated risk in some cases.


Renal failure in McArdle's disease.

Renal failure in McArdle's disease.


Double lip and double lip with blepharochalasis (Ascher's syndrome).


Oral manifestations in Crohn's disease. Report of a case.


Personality and temporomandibular joint dysfunction.


Odontodysplasia. Report of an unusual case and a review of the literature.


Hereditary hemorrhagic telangiectasia. An electron microscopic study.


Epidermal nevus syndrome. Report of a case with unusual oral manifestations.


An unusual dental variant of ovarian teratoma. Report of a case.


Papilliferous ameloblastic fibroma.

Papilliferous ameloblastic fibroma.


A practical method of bleaching tetracycline-stained teeth.


Pantomography today.

Pantomography today.


Dycal therapy for pulp exposures.

Dycal therapy for pulp exposures.


Laser use in endodontics. II.

Laser use in endodontics. II.


Projected artifacts viewed on soft-tissue dental radiographs. Report of a case.


Odontodysplasia.

Odontodysplasia.


Unusual third molar morphology.

Unusual third molar morphology.


Adsorption characteristics of selected commercially available ophthalmic lenses.


Sensitivity of the midbrain to blur.

Sensitivity of the midbrain to blur.


The effect of deep freezing on hamster cheek pouch carcinoma. A preliminary report.


Corneal swelling caused by Allium cepa.

Corneal swelling caused by Allium cepa.


The effects of monocular and binocular intermittent stimulation on stereoscopic judgments.


Contrast sensitivity of the human retina.


Optometric participation in the HMO.

Optometric participation in the HMO.


Dissociated versus monocular cross-cylinder method.


Incidence of glaucoma in optometric practice--an eight year evaluation of 6,580 tonograms.


Central serous retinopathy with transitory monocular hypermetropia--a case report.


A vision census and study of a U.S. Veterans Administration hospital for psychiatric patients.


Mechanical ventilation of newborn infants. II. Effects of independent variation of rate and pressure on arterial oxygenation of infants with respiratory distress syndrome.


Experience using the F. & P. humidifier for pediatric patients.


Primary osteosarcoma of the heart.

Primary osteosarcoma of the heart.


Chronic myelogenous leukemia presenting in blastic crisis.


The high-velocity pulmonary injury. Relation to traumatic wet lung syndrome.


The systemic systolic blood pressure of newborns with low weight. A multiple regression analysis.


A method of three-dimensional analysis of kinematics and co-ordination of equine extremity joints. A photogrammetric approach applying high-speed cinematography.


Psychotherapy with paraverbal therapy in a case of Gilles de la Tourette syndrome.


Bone marrow cytoplasmic buds and their association with hematologic neoplasms.


American College of Dentists sponsors new program for self-assessment and continuing education in dentistry.


Professional conduct and the college.

Professional conduct and the college.


Cytomorphological classification of acute leukaemias.


The American College of Dentists Foundation.


Nutrition teaching in preventive dentistry.


Personality characteristics associated with preventive dental health practices.


Academic performance in dental school: its relation to predental course emphasis.


The dental editor in community dentistry.


Positional signalling along hydra.

Positional signalling along hydra.


Correlation between unrepaired radiation-induced DNA strand breaks and mitotic delay in Physarum polycephalum.


Chemotherapy through lysosomes with a DNA-daunorubicin complex.


Immunoglobulin determinants on lymphocytes of adult, neonatal and foetal pigs.


Role for a 2 -macroglobulin in haemostatic balance.


Myosin light chains of slow twitch (red) muscle.


A possible precursor of immunoglobulin light chains.


Diphasic glucagon release induced by arginine in the perfused rat pancreas.


Regeneration of hydra from reaggregated cells.


Physician care of alcoholics. A survey in central North Carolina.


Sleep insurance: a valid use of hypnotics?


A practitioner's thoughts on our medicine. A challenge for local medical society leadership.


Office management for the dermatologist.


Two stage removal of teeth in orthodontic treatment.


Genital self-mutilation in women.

Genital self-mutilation in women.


The economics of the Begg technique.

The economics of the Begg technique.


Torque application to maxillary incisors.


Color control in staining veneers and jackets.


Chronic granulocytic leukaemia with Ph 1  negative cells in bone marrow and a ten year remission after busulphan hypoplasia.


A comparison of psychomotor and breathalyzer determined alcohol effects of the "cocktail party drinker".


Ketamine anesthesia in ambulatory dental practice.


Baylor Orthodontic Department advises school principals on G.P. Orthodontic qualifications.


Texas dentist answers charges of Baylor orthodontists.


The application of transactional analysis to the orthodontic patient.


A rapid and accurate assessment of the mesial-distal dimensions of any unerupted permanent tooth.


Subtotal transbuccal osteotomy of the face.


Results that count.

Results that count.


Shall we weed out our patients?

Shall we weed out our patients?


The biological effects of a desensitizing solution on the gingival and pulp tissues.


First molar extraction treatment with the Begg technique.


Spare one minute to save one life.

Spare one minute to save one life.


An oral surgeon views dental implants.

An oral surgeon views dental implants.


The "why" and "how" of plaque control.

The "why" and "how" of plaque control.


Mouth protectors for athletes.

Mouth protectors for athletes.


Central hemangioma of the maxilla: case report.


Dentigerous cyst limited to an area below the inferior alveolar canal: case report.


The fashionable tooth.

The fashionable tooth.


Occlusal considerations in preventive care.


Mandibular rest levels with and without dentures in place in edentulous and complete denture-wearing subjects.


Continuous observations of mandibular positions by telemetry.


Silver pins: their influence on the strength and adaptation of amalgam.


The composite resin post and core.

The composite resin post and core.


Law and economics of dental practice.

Law and economics of dental practice.


Prepared and etched enamel walls.

Prepared and etched enamel walls.


Correlation of temporomandibular dysfunction with radiographic findings.


Psychosocial aspects of maxillofacial rehabilitation. II. A long-range evaluation.


A clinical application of practical photography for dentistry.


Menominee County Dental Care Program--6 year summary report.


Health care for all: when, how and how much.


Making a dental plaster case: an introduction to dental technology for fifth and sixth graders.


The potential toxic hazards in the dental laboratory.


Alcohol and highway fatalities. A study of 961 fatalities in North Carolina during the last six months of 1970.


Rehabilitation of patients with spinal cord injuries.


Primary pulmonary aspergillosis. A case report.


Dental education. Henry B. Clark, Jr., Memorial seminar.


An upper midwesterner looks at the American Dental Association.


Alveolar bone loss associated with vascular disease.


Dental management of the irradiated patient.


Periodontal surgery--edentulous area.

Periodontal surgery--edentulous area.


Studies of mice with a balanced complement of 36 chromosomes derived from F 1  hybrids of T1Wh and T1Ald translocation homozygotes. F(1) hybrids with 38 chromosomes, including single T1Wh and T1Ald translocations, resulted when mice homozygous for the Robertsonian translocations T1Wh and T1Ald were crossed. Meiotic studies of the hybrids showed two trivalents, indicating nonhomology of the T1Wh and T1Ald chromosomes. The hybrids had frequent (25%) unbalanced meiotic metaphase II complements; one trisomic mouse resulted from six F(1) crosses. The F(1) crosses also produced one mouse with 36 chromosomes homozygous for both T1Wh and T1Ald, as well as mice with balanced polymorphic complements of 37, 38, 39, and 40 chromosomes. By crossing the F(2), a homogeneous line with 36 chromosomes was established. The line is phenotypically normal, fertile, and has balanced meiotic metaphase II complements. Analysis of the chromosomes of these mice with quinacrine mustard and the Giemsa-banding technique confirmed that T1Wh and T1Ald consisted of chromosomes 5;19 and 6;15, respectively. Crosses between this line and other existing translocation stocks may produce new strains of mice with even further reduction in chromosome number. Accumulation of Robertsonian translocations, a possible evolutionary mechanism in the wild, can be studied in the laboratory. F(1) hybrids from certain crosses are also an important model for human translocation carriers; both have similar meiotic abnormalities and often have aneuploid offspring.


Early contact interactions between mammalian gametes in vitro: evidence that the vitellus influences adherence between sperm and zona pellucida. A study in vitro of interactions between gametes of the golden hamster showed that the spermatozoon associates with the zona pellucida, or outer coat of the ovum, by two successive steps termed attachment and binding. Attachment, apparently the first step in fertilization, is not species-specific; it is insensitive to temperature (2 degrees ) and is reversible. Binding, on the other hand, is species-specific, temperature-sensitive, and irreversible. Experiments with isolated zonae pellucidae indicated that the vitellus (cellular portion of the ovum) influences the interaction between the sperm and the zona pellucida by increasing the time required for the sperm to bind. This effect is exerted on the sperm while they are attached to the zona pellucida.


Intermolecular interaction effects in the amide I vibrations of   polypeptides. Previous perturbation treatments of the Amide I vibrations of beta polypeptides are inconsistent with a detailed normal coordinate analysis of crystalline polyglycine I. This analysis indicates that the D(10) interaction constant is essentially zero, rather than the large value (about 20 cm(-1)) required by the earlier application of the perturbation theory. It is suggested that the previously neglected D(11) term should be included in the perturbation expression, and it is shown that the physical origin of such a term can be accounted for by transition dipole coupling. This mechanism is shown to give a reasonable explanation of splittings of the C=O stretching vibrations in hydrogenbonded carboxylic acid dimers. Its application to beta polypeptides provides a satisfactory interpretation of splittings in the Amide I modes.


Appearance of acetylcholine receptors during differentiation of a myogenic cell line. Acquisition of acetylcholine receptors during differentiation of a clonal myoblast cell line was monitored with a neurotoxin isolated from venom of the Indian Cobra Naja naja. Toxin bound specifically and reversibly to acetylcholine receptors of the differentiated cells. Specificity of the binding reaction was assayed by measurement of the ability of various cholinergic agonists and antagonists to compete with neurotoxin for its binding site. The rate of toxin binding paralleled the rate of inactivation of functional acetylcholine receptors, as measured by iontophoretic application of acetylcholine. Bound toxin was released from the cells with a half-life of about 7 hr. This release was not associated with a decrease in the total number of toxin-binding sites. A slow hyperpolarizing response to acetylcholine seen in myoblasts was insensitive to toxin; the appearance of toxin-binding sites parallels the appearance of fused fibers during differentiation of the muscle cells in tissue culture.


Formation and decay of prelumirhodopsin at room temperatures. We have excited detergent-solubilized bovine rhodopsin at room temperature with 530-nm light pulses from a mode locked laser, and have observed the appearance and decay of a transient species that absorbs more strongly at 560 nm than does ground-state rhodopsin. Our data show that the absorbing intermediate appears in a time that is at least as short as the experimental resolution (about 6 psec) and decays with a life time of about 30 nsec. The extremely fast risetime supports the hypothesis that prelumirhodopsin is the product of the primary photoprocess.


3-hydroxypropionate: significance of  -oxidation of propionate in patients with propionic acidemia and methylmalonic acidemia. [l-(14)C]Propionate administered intravenously was metabolized to methylmalonate, to 3-hydroxypropionate, and to methylcitrate in the urine of a patient with methylmalonic acidemia. L-[U-(14)C]Isoleucine and L-[U-(14)C]valine were also converted to urinary methylmalonate and to 3-hydroxypropionate in the patient. Two patients with propionic acidemia due to a defect in propionyl-CoA carboxylase metabolized [l-(14)C]propionate to uninary methylcitrate and 3-hydroxypropionate. The appearance of radioactive 3-hydroxypropionate in the urine after the administration of these compounds indicates that beta-oxidation of propionyl-CoA through acryloyl-CoA was functioning in these patients. The conversion of valine to 3-hydroxypropionate suggests that valine is oxidized by way of propionate and propionyl-CoA in man.


Induction of avidin synthesis by RNA obtained from chick oviduct. RNA was extracted from oviduct, shell gland, and liver of chicks treated with diethylstilbestrol and a combination of diethylstilbestrol and progesterone. Preparations containing 500 or 2500 mug of RNA were put in the oviductal lumen of diethylstilbestrol-treated chicks for 24 hr, and the avidin content of the oviduct was determined by measurement of [(14)C]biotin binding. The results of the present study demonstrate that oviduct RNA from chicks treated with progesterone induces synthesis of avidin in chick oviduct. In contrast, liver or shell gland RNA from chicks treated with progesterone, and liver or oviduct RNA from chicks treated with diethylstilbestrol are incapable of inducing avidin synthesis. The inducing capacity of oviduct RNA is destroyed when it is treated with ribonuclease. It is hypothesized that progesterone induces the synthesis of new species of oviduct RNA, which serve as messenger(s) for avidin synthesis. This hypothesis is offered in consideration of the findings: (i) that the residual amount of progesterone present as a contaminant in oviduct RNA from chicks treated with progesterone is far too low to account for the induced avidin synthesis; (ii) that such oviduct RNA from chicks treated with progesterone induces a slight synthesis of avidin in chick shell gland, which ordinarily does not produce avidin in response to progesterone administration and; (iii) that such RNA added in vitro to minces of oviductal tissues incubated in biotin-free medium for 24 hr induces synthesis of avidin.


Identification of the cardiac beta-adrenergic receptor protein: solubilization and purification by affinity chromatography. A protein that binds catecholamines with a specificity parallel to that of their in vivo effects on cardiac contractility (isoproterenol > epinephrine or norepinephrine > dopamine > dihydroxyphenylalanine) was solubilized from a microsomal fraction of canine ventricular myocardium. The binding protein was purified 500 to 800-fold by solubilization and subsequent affinity chromatography with conjugates of norepinephrine linked to agarose beads. Purified beta-adrenergic binding protein exists in two forms, corresponding to molecular weights of 40,000 and 160,000. The purified material has a single association constant, 2.3 x 10(5) liters/mol (as compared to two association constants, 10(7) and 10(6) liters/mol, for the binding protein in particulate form) but retains the identical binding specificity for beta-adrenergic drugs and antagonists.


A unifying hypothesis concerning the nature of malignant growth. It is suggested that the crucial change in a malignant cell is an alteration in the cell surface membrane that results in increased internal concentrations of nutrients that regulate cell growth.


Similarities between the conformation of arsanilazotyrosine 248 of carboxypeptidase A    in the crystalline state and in solution. Modification of carboxypeptidase A(gamma) crystals (Anson) with diazotized arsanilic acid specifically labels tyrosine 248; at pH 8.2 the modified enzyme gives yellow crystals, but a red solution. It has been suggested that arsanilazotyrosine 248 forms a complex with the Zn cofactor accounting for the red color in solution, but that a complex is not formed in the crystal. However, the crystal structure of carboxypeptidase A(gamma) is unknown. We show here that crystals of carboxypeptidase A(alpha), whose crystal structure has been determined, are red both in solution and in the crystalline state (at pH 8.2) after modification with diazotized arsanilic acid. These new data are of importance in relating the structure in the crystalline state to the catalytic mechanisms, as based on the x-ray diffraction evidence. The activity of carboxypeptidase A in the crystal and in solution has a ratio of only 1/3 for the alpha form, in contrast to the ratio of 1/300 for the gamma form, with carbobenzoxyglycyl-L-phenylalanine as a substrate.A pH-jump experiment monitored by stopped-flow kinetics in a split-beam apparatus has revealed a single exponential rate when a solution of arsanilazotyrosine 248 carboxypeptidase A(alpha) at pH 6.7 (yellow) is increased to pH 8.5 (red). The rate constants obtained in this experiment are 6.1 sec(-1) at 3.0 mg/ml and 7.2 sec(-1) at 1.6 mg/ml concentration of enzyme.


The rapid turnover of RNA polymerase of rat liver nucleolus, and of its messenger RNA. Turnover rates of the components of systems for RNA synthesis of rat-liver nucleus, nucleolus, and nucleoplasm were investigated. Cycloheximide administered in vivo selectively diminished nucleolar RNA synthesis in vitro. In contrast to the relatively stable nucleoplasmic RNA polymerase, nucleolar RNA polymerase (polymerase I) from rat liver decays rapidly upon cycloheximide administration, following pseudo-first order kinetics with a half-life of about 1.3 hr. Cycloheximide elicits this effect not through direct interaction with nucleolar RNA polymerase itself, nor by alteration of template function, but rather by inhibition of de novo synthesis of one or more of the protein components of nucleolar RNA polymerase. Similarly, when actinomycin-D was administered in vivo to inhibit RNA synthesis, the rate of decay of nucleolar RNA polymerase, assayed in the presence of exogenous poly d(A-T) template, was similar to that observed after cycloheximide administration. Thus, the messenger RNA(s) that codes for one or more of the catalytically essential polypeptide components of this enzyme turn over very rapidly with a half-life considerably shorter than 1.3 hr. The rapidity of turnover of both the enzyme protein and its messenger RNA(s) renders nucleolar RNA polymerase highly responsive to altered transcriptional, translational, or post-translational modulation. The marked differences in turnover rates of nucleolar and nucleoplasmic RNA polymerases indicate that at least certain of the protomeric components of nucleolar RNA polymerase I are distinct from those of nucleoplasmic RNA polymerases II and III.


Specification of positional information in retinal ganglion cells of Xenopus: stability of the specified state. In the normal development of retinotectal connections, the site in the tectum at which an optic fiber synapses is related to the position of its ganglion-cell body in the retina. How and when the ganglion cells acquire information about their positions is unknown, but the positional information that each ganglion cell will ultimately act upon is determined or specified at embryonic stages 28-32 in the clawed frog, Xenopus laevis. Here we report that once positional information has been so specified, it remains stable when the eye is "back-grafted" into the orbit of a stage-28 host, or cultured in vitro for up to 10 days before grafting into the orbit of a stage-38 host. Thus, the ganglion cells of these eyes form tectal connections appropriate to their original positions in the donor orbits and independent of their final positions in the host orbits. We conclude that specification of positional information involves stable changes in the phenotypic properties of the differentiating retinal cells that (i) render the cells refractory to information about changes in their positions after stage 32 and (ii) commit each ganglion cell to the development of a unique property (locus specificity) that predisposes its axon to synapse at a particular locus in the retinotectal map.


Persistence of thymidine kinase activity in mitochondria of a thymidine kinase-deficient derivative of mouse L cells. The cell line LM(TK(-)) Cl 1D, a derivative of mouse L fibroblasts deficient in thymidine kinase (EC 2.7.1.21) that shows very little thymidine kinase activity in extracts of whole cells as compared to the parental line, and that does not incorporate thymidine or 5-bromodeoxyuridine into nuclear DNA, has maintained the capacity to incorporate these precursors into mitochondrial DNA at a substantial rate. The amount of [methyl-(3)H]thymidine incorporated into mitochondrial DNA of LM(TK(-)) Cl 1D cells after long-term labeling has been conservatively estimated in different experiments to be between 30 and 60% of that incorporated into mitochondrial DNA or nuclear DNA of strain A9, an L-cell derivative without any thymidine-kinase dificiency; by contrast, the incorporation of thymidine into nuclear DNA of Cl 1D cells is less than 1% of that in A9 cells. These results strongly suggest that the loss of thymidine kinase activity in the extramitochondrial compartment of LM(TK(-)) Cl 1D cells has not been accompanied by the loss of the mitochondria-associated enzyme activity, pointing to a different genetic or epigenetic control of the extramitochondrial and mitochondrial enzymes.


Inactivator of the third component of complement as an inhibitor in the properdin pathway. Evidence has been obtained that a single protein, known to modulate classical complement activation, also acts as an inhibitor in the properdin or alternate complement pathway. A highly purified inactivator of the third component of complement (C3) from human serum inhibited the proteolysis of Factor B in the properdin system (glycine-rich beta-glycoprotein) by glycine-rich beta-glycoproteinase. The inhibition was by the enzymatic destruction of glycine-rich beta-glycoproteinase activity. The major fragment of C3, C3b, which is the only known substrate of the C3 inactivator, blocked the destruction of glycine-rich beta-glycoproteinase by the C3 inactivator. Thus, in its inhibition of the porperdin pathway, the C3 inactivator destroys both the active form of glycine-rich beta-glycoproteinase and a protein involved in the conversion of the zymogen form of this enzyme (proglycine-rich beta-glycoproteinase) to its active form. The increased susceptibility to infections in a patient homozygous for deficiency of the C3 inactivator demonstrates the biologic significance of this protein.


Configuration of the C(20) epimer of 7,8-dihydrobatrachotoxinin A. 7,8-Dihydrobatrachotoxinin A is an intermediate in the synthesis of batrachotoxin, the extremely potent venom from the Colombian frog Phyllobates aurotaenia. A crystal structure analysis by x-ray diffraction has confirmed that the intermediate is identical with the natural batrachotoxinin A except for the saturation of the C(7)-C(8) bond. There are seven asymmetric carbon atoms in the molecule. The cis A/B and C/D ring junctions cause the molecule to assume the characteristic shape of cardioactive steroids. A cage is formed from the A-ring, atom C(9), and the O atom that makes the ether linkage between C(3) and C(9).


Dog homologue of human  2 -microglobulin. The amino-acid sequence of human beta(2)-microglobulin, a protein of 100 residues, is related to parts of the constant region of IgG heavy chain. The dog homologue of human beta(2)-microglobulin has now been isolated and its amino-acid sequence has been partially determined. The two proteins (human and dog beta(2)-microglobulins) are demonstrably different at only 6 or 7 of the 42 positions examined. Use of the dog should permit experimental investigation of the functional relationships of beta(2)-microglobulin to immunoglobulins and the immune system. beta(2)-Microglobulin has also been detected in serum from a chimpanzee. The gene for beta(2)-microglobulin may correspond to the end portion of an immunoglobulin heavy chain gene.


In vitro aggregation of cytoplasmic microtubule subunits. The colchicine-binding protein in procine-brain tissue is a dimer of molecular weight 110,000 that is believed to be the subunit of neuronal microtubules. Conditions are established under which the dimers aggregate with reproducible kinetics. This aggregation reaction, which is monitored by development of turbidity, has the following characteristics: (a) Colchicine inhibits development of turbidity; (b) the reaction inhibited by colchicine is reversed by long-wave ultraviolet irradiation; (c) the aggregation is temperature-dependent; (d) the reaction is nucleotide triphosphate-specific, being stimulated by 1 mM GTP; (e) the reaction appears to be specific for microtubule subunits since in the presence of other added proteins and in curde cell extracts, only microtubule subunits aggregate. On the basis of these criteria, we conclude that we have established an in vitro system for the aggregation of microtubule subunits that shares some of the properties characteristic of the in vivo assembly of cytoplasmic and spindle microtubules.


Addition of chemical and osmotic free energies through negative interaction of protein-bound ligands. Simple free energy considerations show that an effector ligand, Y, bound to a protein can modify the standard free energy change of the reaction P - X + D - R = P - R + D - X, where P is a protein, D - R a small molecule, and X a group in the protein that interacts negatively with Y. By consideration of a three-compartment system containing the protein, an X-acceptor (A - R), an X-donor (D - X), and the ligand Y present at two different concentrations in the inner and outer compartments, it is shown that the protein can perform under steady-state conditions the addition of the free energy in the Y concentration gradient to that of the chemical reaction A - X + D - R = A - R + D - X. This free energy addition can effectively generate a high energy X-donor from a low energy one and may be of importance in metabolism, particularly in the oxidative phosphorylation of ADP.


Fusion of mammalian somatic cells by microsurgery. Mammalian somatic-cell hybrids can be formed in a direct and precise manner by microsurgery. Fusion of cells brought about in this way permits selection of specific, identifiable cells of the same or different types or species and their fusion at telophase.


An adenosine triphosphate-phosphate exchange catalyzed by a soluble enzyme couple inhibited by uncouplers of oxidative phosphorylation. The sulfenic acid form of glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12), which is an acyl phosphatase, will catalyze an acetyl phosphate-Pi exchange reaction. This exchange reaction is reversibly inhibited by the uncouplers of oxidative phosphorylation, 2,4-dinitrophenol, m-Cl carbonylcyanide-phenylhydrazone, pentachlorophenol, and 5-chloro-3-tert-butyl-2'-chloro-4'-nitrosalicylanalide, and is irreversibly inhibited by cyanide and dicumarol. An ATP-Pi exchange reaction similar to that catalyzed by mitochondria can be simulated by a system composed of oxidized glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase (EC 2.7.1.28), 3-phosphoglycerate, ATP, (32)Pi, and appropriate cofactors. The ATP-Pi exchange is inhibited by uncouplers of oxidative phosphorylation. Higher concentrations of uncouplers will also inhibit the ATPase reaction catalyzed by the coupled enzyme system. The exchange reactions catalyzed by the sulfenic acid form of glyceraldehyde-3-phosphate are consistent with a sulfenyl carboxylate intermediate. On the basis of these observations, a reaction scheme has been postulated for covalent coupling in oxidative phosphorylation that includes a sulfenyl carboxylate as a nonphosphorylated, high energy intermediate and an acyl phosphate as a phosphorylated, high energy intermediate.


Composite resins...for the general practitioner.


Continuing education--free.

Continuing education--free.


A mechanism of action for carboxypeptidase A. In an attempt to gain a better understanding of the mechanism of action of carboxypeptidase A (EC 3.4.2.1), many kinetic studies have been undertaken using numerous substrates-both esters and peptides-that have exhibited substrate linearity, inhibition, activation, and sigmoid-shaped rate plots. Numerous interpretations of the kinetic data have been proposed, none of which are fully in accord both with kinetic data and x-ray crystallographic studies. Much of the kinetic data has been interpreted using multisite binding while the x-ray information seems to severely restrict these possibilities. We have examined the feasibility of a simple model with a single active site, without modifier sites, that allows only one substrate molecule to bind the enzyme at a time. A random-pathway model was identified that simultaneously accounts for the nonlinear kinetic data and meets the restrictions imposed by the x-ray crystallographic studies.


Surgical intervention in the endo-perio complex. A case report.


The follow-up to Flexner.

The follow-up to Flexner.


Adenovirus-2 DNA contains an inverted terminal repetition. Denaturation and renaturation of the adenovirus-2 chromosome (a duplex rod) generates single-stranded circles of unit length. These circles can be opened into linear DNA molecules by digestion with exonuclease III, indicating that hydrogen bonding between the two ends of an adenovirus strand is responsible for maintaining the rod in a circular state.The formation of adenovirus single-stranded circles, and their sensitivity to exonuclease III, indicate that the mature adenovirus-2 DNA molecule contains an inverted terminal repetition. That is, the base sequence at one end of the molecule is inverted and appears again at the other end of the molecule. This is the first example of such a structure, and its function is unknown.


Annual report of the committee on maternal welfare.


Nucleotide sequence at the binding site for coat protein on RNA of bacteriophage R17. The binding of a few molecules [1-6] of RNA bacteriophage coat protein to 1 molecule of RNA represses in vitro translation of the RNA synthetase cistron. Digestion of the complex, R17 coat protein-R17 RNA, by T1 RNase yields an RNA fragment bound to the coat protein. The nucleotide sequence of this fragment (59 residues) reveals that it contains the punctuation signal between the coat protein and RNA synthetase cistrons, suggesting that this is the site on the RNA where the coat protein acts as a translational repressor.


Paroxysmal ventricular tachycardia.

Paroxysmal ventricular tachycardia.


A replicating RNA molecule suitable for a detailed analysis of extracellular evolution and replication. The aim of the present study is to make available a replicating molecule of known sequence. Accordingly, we sought a molecule that has the following properties: (a) replicates in vitro in a manner similar to phage Qbeta RNA; (b) produces antiparallel complementary strands that can be separated from one another; and (c) is small enough to yield its sequence with reasonable effort. We report here the isolation of a replicating RNA molecule that contains 218 nucleotides and possesses the other features desired for a definitive analysis of the replicating mechanism. Despite its small size, this molecule can mutate to previously determined phenotypes. It will, therefore, permit the precise identification of the base changes required to mutate from one phenotype to another in the course of extracellular Darwinian selection experiments.


[Partial jaw resection in central giant cell granulomas].


Studies on the frequency of and reasons for side reactions after regional anaesthesia with mepivacaine with and without vasoconstrictors.


Vascular effects of the isomers of mepivacaine.


Perfusion and diffusion in shock. A study of disturbed tissue-blood exchange in low flow states in canine skeletal muscle by a local clearance technique.


Colony growth of peripheral blood cells from patients with acute lymphocytic leukemia.


Structure and removal of carious dentin.


Assessment of occlusal status the matched-pair similarity technic.


Intensive chemotherapy of acute myelogenous leukaemia.


Neuropsychological test performance before and after symptom removal in a child with Guilles de la Tourette syndrome.


Skill learning and performance. The obtaining and processing of information: some basic issues relating to analysing inputs and making decisions.


Platelet disorders.

Platelet disorders.


Skill learning and performance. Movements to match environmental demands.


Natural vs. unnatural sciences in the healing arts.


Skill learning and performance. Maximizing goal attainment.


Skill learning and performance. Task analysis: a consideration for teachers of skills.


Skill learning and performance. Implications for physical education.


A suggested direction for the study of motor performance by physical educators.


The dry mouth adverse reaction syndrome in the geriatric patient.


Skill learning and performance. Postscript.


The distal wedge operation in periodontal therapy; a two year evaluation.


Treatment of recurrent aphthous ulcers with anabolic drugs. Preliminary report.


Diseases of the maxillary sinus.

Diseases of the maxillary sinus.


Extraosseous osteogenic sarcoma.

Extraosseous osteogenic sarcoma.


Anabolic therapy of recurrent aphthous ulcers.


Medical conditions affecting dental treatment planning.


Caries aetiology in Papua New Guinea. Associations of tooth size and dental arch width.


Water fluoridation in New South Wales, 1956-1971.


Perception: its meaning, significance and control in dental procedures. 3. Clinical aspects.


Electromyography of the masseter and anterior temporalis muscles in subjects with potential temporomandibular joint dysfunction.


The condensation of amalgam by a group of general practitioners.


Sterile storage in dentistry.

Sterile storage in dentistry.


Dental legislation.

Dental legislation.


5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in the treatment of advanced acute lymphocytic leukemia in children.


Prediction of the response of patients with acute nonlymphocytic leukemia to cytosine arabinoside (NSC-63878) therapy.


Intermittent therapy with 6-mercaptopurine (NSC-755) and methotrexate (NSC-740) given intravenously to adults with acute leukemia.


Different neoplastic response of mice and rats to infection by murine sarcoma virus (Moloney).


Establishment of a virus-persistent cell line and deviation of malignant cell clones from rat osteosarcoma induced by a murine sarcoma virus (Moloney).


Gingival reattachment after surgery in man: an electron microscopic study.


Alteration of mast cell densities in experimentally inflamed human gingivae.


Preserved sclera in periodontal surgery.


The relationship between the width of keratinized gingiva and gingival health.


Pedicle and free mucosal grafts--a case report illustrating these procedures.


Differential diagnosis of Gilles de la Tourette's syndrome.


Laryngeal and pharyngeal edema of obscure origin.


Combination therapy of acute lymphocytic leukemia of children.


Total therapy of acute lymphocytic leukemia.


Morphologic discordance in acute leukemia.


Topography of membrane concanavalin A sites modified by proteolysis.


Origin of concatemeric T7 DNA.

Origin of concatemeric T7 DNA.


Methylation of bovine rhodopsin.

Methylation of bovine rhodopsin.


Tetrodotoxin interference of CNS excitation by glutamic acid.


Natural human antibodies to "hidden" membrane components.


Selection pressures on homologous proteins of varied activities.


Reaginic antibody to tumour and alloantigens in mice.


Inhibition of adenosine uptake by platelets.


Adenosine inhibition of human platelet aggregation by ADP.


Selective uptake of 5-hydroxytryptamine by axonal processes in Helix pomatia.


Radioimmunoassay of an antibiotic: gentamicin.


Dynamics of insulin action on mammary epithelium.


Genetic control of chromosome pairing in hexaploid oats.


Externally suppressible +1 "glycine" frameshift: possible quadruplet isomers for glycine and proline.


Strep. sanguis, Strep. mutans and Strep. salivarius in saliva. Prevalence and relation to caries increment and prophylactic measures.


The effect of physical training on temporomandibular joint clicking.


The importance of an even shoulder preparation in porcelain crowns.


Evaluation of healing following experimental pulpotomy of intact human teeth and capping with calcium hydroxide.


Improvement of stone dies by imbibition of methyl methacrylate under vacuum.


Leukocyte alkaline phosphatase. Fluctuations with disease status in chronic granulocytic leukemia.


Skin thickness and collagen content in some endocrine, connective tissue and skin diseases. A roentgenographic and biochemical study.


Lymphocytotoxins in leukaemia.

Lymphocytotoxins in leukaemia. Fifteen out of 51 patients with leukaemia have produced a lymphocytotoxin in their serum which reacts with their own and a high percentage of all other lymphocytes. This is probably a protein, but not an antibody. It has been detected only before or early during cytotoxic treatment, or during a relapse. It is postulated that the lymphocytotoxin is a specific protein produced by the leukaemic cells, which may facilitate their spread in the body.


Helping dentists to help the people.

Helping dentists to help the people.


Ribonuclease-sensitive endogenous DNA polymerase activity and DNA-directed DNA polymerase in human tissue culture cell lines.


Lymphocyte blastogenesis to human leukemia cells and their relationship to serum factors, immunocompetence, and prognosis.


Your security.

Your security.


Expenditures on personal health care (a) Canada 1965-70.


The multiple gutta percha point technique for filling anterior root canals.


Women dentists: some circumstances about their choice of a career.


Expectations of "sick role" exemptions for dental problems.


Continuing education in dentistry: an attitude survey in British Columbia.


The use of rubber dam in endodontics.

The use of rubber dam in endodontics.


Utilization of ( 3 H)-serine by ameloblasts of rats receiving sub-mottling doses of fluoride.


Cellular hypersensitivity in guinea pigs immunized with BCG vaccine through the gingival crevice.


Mucocele formation in cats by glandular duct ligation.


Effect of diet in West Africa on human salivary amylase activity.


A fluorimetric study of  -glucuronidase and  -acetylgalactosaminidase from the pulp of the rat incisor.


The effects of chlorhexidine and fluoride combinations on the potassium, sodium and phosphorus content and acid production of cariogenic streptococci.


The effect of iron salts on experimental dental caries in the hamster.


Structure of approximal human dental plaque as observed by scanning electron microscopy.


The effects of surgical desalivation of the rat upon taste acuity.


Effect of particle size on reactions of powdered sound human enamel and dentine with stannous fluoride solution.


Fabry's disease (ceramide trihexosidase deficiency): diagnostic confirmation by analysis of dental pulp.


The recovery of microorganisms from the fissures of rat molar teeth.


Sensitization of rabbits with chlorhexidine-protein complexes.


Reaction of dextrans with antisera to teichoic acids.


Lymphosarcoma terminating in acute myelogenous leukemia.


Unions for physicians?

Unions for physicians?


Examination, "Is that all there is" to medical licensing?


Managerial characteristics of dentists. I. Styles of management inventory.


Preparing dental hygiene students for expanded functions.


Student research in the dental curriculum.


Location and evaluation of prospective faculty members.


Some characteristics of postgraduate dental education programs.


Affiliations in dental auxiliary education.


Statistical analysis of predictive and achievement variables for dental hygiene students.


Dental studies in Poland.

Dental studies in Poland.


NIDR reviews progress of five dental research institutes.


1972 thoughts on "Why not a Department of Social Dentistry"?


Clinico-pathological studies on snakebites in Taiwan.


A study on social characteristics of health personnel and their training needs in three health bureaux and 49 health stations in northern part of Taiwan Province.


Aberrant pancreas in a case of intussusception.


A retrospective study on bronchial asthma in Shulin township, Taipei County, Taiwan.


A sympathetic reflex elicited by distension of the mesenteric venous bed. 1. The proximal ends of the distal portions of severed nerves coming from the small intestine were monitored for nerve impulses. When the mesenteric venous pressure was increased by mechanical obstruction of the portal vein there was a proportional increase in the frequency of afferent action potentials, the frequency falling immediately the venous pressure was reduced. The stimulus for the increased rate of nerve discharge appeared to be pressure within the mesenteric venous bed and not anoxia, for obstruction of the arterial supply to the gastrointestinal tract did not activate the same fibres.2. Obstruction of the portal vein led to an increased efferent nervous discharge to the intestines. The reflex increase persisted after bilateral vagotomy, after transection of the spinal cord at the level of C7 and after section of the hepatic nerves, but was abolished by section of the intestinal nerves.3. It is suggested that the spinal reflex is concerned with local distribution of blood and that the mesenteric venous ;volume' or ;stretch' receptors which initiate the reflex are similar to those described elsewhere in the body.


Isolation and hybridization kinetics of messenger RNA from Dictyostelium discoideum.


Function of peptide antibiotics in sporulation.


Distinction between two types of beta-thalassaemia by inducibility of the cell-free synthesis of beta-chains by nonthalassaemic soluble fraction.


Synthesis of mouse haemoglobin and globin mRNA in leukaemic cell cultures.


Nucleolar RNA synthesis during meiosis of lily microsporocytes.


Evidence for close linkage of human amylase loci.


Effect of prostaglandins E 1  and F 1   on biosynthesis of collagen.


Release of prostaglandins in ocular inflammation in the rabbit.


Specific noradrenergic neurones destroyed by 6-hydroxydopamine injection into newborn rats.


Application of a new model of species competition to Drosophila.


Effect of metabolic depletion on the membrane permeability of smooth muscle cells and its modification by La 3+ .


Enhancement of overall plant growth, a new response to brassins.


Tissue ageing as a factor in juvenile cancers.


A case of Gilles de la Tourette's syndrome in a brain-damaged child.


Fatal pulmonary leukostasis following treatment in acute myelogenous leukemia.


Early complications of long-term respiratory support.


Precision attachments.

Precision attachments.


The semi precision snap lock partial denture.


Observations on the evolution of crown post design.


Modern trends in dental jurisprudence.

Modern trends in dental jurisprudence.


Oral physiotherapy and its meaning in general dental practice.


Dental materials science in education and practice--its past and future.


The assessment of a patient for orthodontic treatment in general pracitce.


Essential features of complete denture construction.


Cystic ameloblastoma: a case report.

Cystic ameloblastoma: a case report.


Complications which may be encountered in wound healing.


Simple "endo' preps".

Simple "endo' preps".


Hereditary aspects of the etiology of the oral tori. (Literature review).


Growth of leukemic cells in culture.

Growth of leukemic cells in culture.


Minnesota Dental Association's efforts to identify and remedy dental health manpower problems.


The Air-Viva resuscitator and a discussion on the diagnosis and treatment of respiratory emergencies.


Dentistry's role in developing dental health manpower data and strategies at the state and local level.


Some aspects of drug allergy.

Some aspects of drug allergy.


The foundation and introduction of dental anaesthesia in Australia.


The research worker and MEDLARS.

The research worker and MEDLARS.


The toxic potentialities of imipramine.

The toxic potentialities of imipramine.


A summary of dental anaesthesia and sedation techniques.


How safe is your office?

How safe is your office?


Your fees: down she goes.

Your fees: down she goes.


Dear Juli: when you need a way with children.


Acupuncture in dentistry.

Acupuncture in dentistry.


Updating knowledge.

Updating knowledge.


ASDA goes on its own.

ASDA goes on its own.


The ecology of the dental suite.

The ecology of the dental suite.


New money for student loans.

New money for student loans.


What makes a good dental teacher?

What makes a good dental teacher?


Inside story--dentistry behind prison walls.


A comparative study of the functionally generated path and techniques utilizing a semi-adjustable articulator in the construction of a fixed bridge.


Sickle cell anemia and the dentist.

Sickle cell anemia and the dentist.


Distribution and toxicity of  230 Pu in bone.


Biological effectiveness of  237 Np.

Biological effectiveness of  237 Np.


239 Pu: problems of its biological effect.


Life shortening consequent to internal irradiation from  239 Pu.


Some late effects after a single inhalation of 239 Pu and 241 Am in dogs.


New challenges to medical care.

New challenges to medical care.


Gerodontics.

Gerodontics.


Thoughts on general anaesthesia for periodontal surgery.


A combined restorative and periodontal chart for everyday use.


Tokelau Island dentistry.

Tokelau Island dentistry.


What's your diagnosis? Fibroma.

What's your diagnosis? Fibroma.


A modified form for blade type endosteal implant.


Cement leakage and retention of threaded and non-threaded endodontic implants.


Complications resulting from dento-surgical operations in the area of the maxillary sinus. Surgical closure combined with radical operation in the maxillary sinus. (With changes of the mucosa of the maxillary sinus).


Spinal and supraspinal inhibition of somato-sympathetic reflexes by conditioning afferent volleys.


Contact allergy with Scutan.

Contact allergy with Scutan.


Papilloma of the oral mucosa.

Papilloma of the oral mucosa.


Tooth transplantation: child--mother.

Tooth transplantation: child--mother.


Use of coffin-springs.

Use of coffin-springs.


Oral rehabilitation. (II).

Oral rehabilitation. (II).


Design principles for orthodontic screws. (II).


Clinical photography in the dental practice. (I).


Incorrect diagnosis of a misplaced premolar.


Peritonsillar abscess associated with tonsillar diphtheria.


The Federal Government.

The Federal Government.


Dental community health summer traineeships for MCV students.


Symptomatology of resectable periampullary carcinoma.


Cryosurgery of the oral mucosa: a study of the mechanisms of tissue damage.


Unusual fracture of a lower canine: long-term temporary conservation.


Rampant caries and the salivary glands. A case report.


Modern trends in geriatric medicine.

Modern trends in geriatric medicine.


The horizontally impacted third molar.

The horizontally impacted third molar.


The tooth surface in periodontal disease.


Dimple-hinge attachments for partial dentures.


Osteoblastoma--benign or malignant percursor? Report of a case.


Group psychotherapy: current concepts and styles.


The abortion explosion.

The abortion explosion.


Intrahypothalamic exploration of androgen-sensitive brain loci in neonatal female rats.


Mortality in syngeneic rat parabionts of different chronological age.


Alcohol and alcoholics: a behavioral approach.


New concepts in ultramicro analytic systems for the '70s.


A spectrofluorimetric study of human lysozyme.


Bone and cartilage in malignant tumours of the urinary bladder.


Variation in wild populations of Papaver dubium. V. The application of factor analysis to the study of variation.


Sectoring and recombination in illegitimate di-mon matings of Schizophyllum commune.


Some statistical aspects of partitioning genotype-environmental components of variability.


Developmental variation of chiasma frequency in Chorthippus brunneus.


Busulphan lung.

Busulphan lung.


The acrylics. A brief survey of the acrylics and their properties which lead to success or failure in dentistry.


EDPAC--what and why.

EDPAC--what and why.


Total hip replacement with cement fixation: a preliminary report.


Use of teflon in hypernasal speech.

Use of teflon in hypernasal speech.


Two versions of the 1938 hurricane.

Two versions of the 1938 hurricane.


Dental handicaps: a challenge in mental retardation.


Hearing problems and the cerebral palsy child.


Being different.

Being different.


San Francisco's unloved statues and their dentist-donor Dr. Henry D. Cogswell.


The art of dental assisting. II.

The art of dental assisting. II.


Group practice. II.

Group practice. II.


Chemotaxis of human basophil leucocytes.


Considerations for successful treatment of the blade-vent endosseous implant.


A clinical study of local anesthesia by jet injection.


Construction of a precision attachment retained appliance.


The influence of temperature on compressive, tensile and shear stresses and micro-structure of dental amalgam.


A clinical study on balanced contact at the predetermined functional ranges of mandibular movement.


Microleakage II--factors affecting the sealing efficiency of restoration materials.


Studies in occupational dentistry. The effect of glass-blowing on conditions of the oral cavity.


A positive guide to the selection of anterior teeth.


Oral manifestations in diabetic patients.


Forceps technique.

Forceps technique.


Peer review.

Peer review.


Periapical lesions--types, incidence and clinical features.


Studies in tooth wear.

Studies in tooth wear.


The presence of coliforms in root canals: preliminary findings.


Occlusion and treatment in patients with advanced periodontal disease.


Prophylactic use of antibiotics in periodontal surgery.


Composite restorative materials filled direct filling resin.


A comparative evaluation of the effect of trace elements on rehardening of human dental enamel.


Clinical evaluation of various chemicals and techniques of bleaching of discolored root filled teeth.


Can a freshman dental student identify with the profession?


Tax tips.

Tax tips.


Preventive operative dentistry: polishing amalgams.


Maxillary osteotomy--surgical orthodontics.


Examination and diagnosis in endodontics.


The A.D.A. viewpoint.

The A.D.A. viewpoint.


Thoughts from a district society.

Thoughts from a district society.


The grass-root feeling.

The grass-root feeling.


Dentistry anbd the national health debate: what next?


Adapting preventive dentistry to school programs: report of a conference.


Age changes in the periodontium and oral mucous membranes.


Introducing kindergartners to dental health or the story of Super Brush and the Molars.


Dental education in Missouri--1971-72.

Dental education in Missouri--1971-72.


Acute lymphocytic leukemia. (In remission) with subsequent periapical abscesses of lower central incisor teeth: report of a case.


Reflex firing in the lumbar sympathetic outflow to activation of vesical afferent fibres. 1. Activation of vesical afferent fibres in the Agammadelta range by electrical stimulation of the pelvic nerve or by bladder distension elicited reflex firing in hypogastric nerves and in preganglionic nerves to the inferior mesenteric ganglion.2. The multisynaptic reflex was present in cats with an intact spinal cord and in acute and chronic spinal animals (transections at T10-T12). The reflex pathway was partially crossed in the sacral cord, and in the periphery at the level of the inferior mesenteric ganglia. In contrast, an inhibitory response to raised intravesical pressure was mediated by a supraspinal inhibitory mechanism which was activated in parallel with the micturition reflex.3. Since enhancement as well as depression of sympathetic firing accompanied reflex micturition, it is concluded that at least two distinct populations of lumbar preganglionic neurones are responsive to vesical afferent activity: one population being excited, the other depressed, during micturition. The latter population may be involved in an inhibitory feed-back mechanism on to the bladder.


The chiropody course.

The chiropody course.


Courses at Massey.

Courses at Massey.


The new alliance.

The new alliance.


Mouthful of hot potato.

Mouthful of hot potato.


Nitrous oxide analgesia and endodontic practice.


An experimental analysis of the tachycardia that follows vagal stimulation. 1. Postvagal tachycardia, the transient increase in heart rate that follows the sinus bradycardia elicited by vagal stimulation, was investigated in thirty chloralosed cats. Maximum postvagal tachycardia was elicited by stimulation at frequencies of 20-60 Hz with train durations of 30-90 sec. A positive correlation was demonstrated between the magnitudes of postvagal tachycardia and of the preceding sinus bradycardia.2. Postvagal tachycardia was not affected by either spinal transection at C7 or by administration of propranolol (1.5 mg/kg I.V.), but was abolished by the administration of atropine (2.0 mg/kg I.V.).3. Postvagal tachycardia was observed to follow the vagal bradycardia induced reflexly either by administration of phenyldiguanide (100-300 mug I.V.) or by stimulation of the aortic depressor nerve.4. In the isolated atria-vagus preparations from six rabbits a positive correlation was demonstrated between the magnitude of postvagal tachycardia and of the preceding bradycardia elicited by vagal stimulation.5. Continuous intracellular recordings were obtained from four sinuatrial node pace-maker cells in the isolated atria-vagus preparation of the rabbit before, during and after vagal stimulation. During postvagal tachycardia the slope of the diastolic prepotential, the maximum diastolic potential, threshold potential and the overshoot were found to be increased; these changes are different from those found in pace-maker cells during adrenergic activation.6. These findings demonstrate that postvagal tachycardia is not mediated by sympathetic adrenergic mechanisms, but suggest that it is dependent upon the preceding vagal bradycardia and may be related to an increase in net sodium influx into pace-maker cells initiated by the hyperpolarization of the pace-maker cell membrane during and immediately after vagal stimulation.


Hers was a great era.

Hers was a great era.


Safety...a tutor sister's view.

Safety...a tutor sister's view.


Proposed legislation to create a new dental auxilary. The 'Dental Technologist'.


The present state and development of public health dentistry in Western Europe.


In the spotlight...Canada's oldest Olympic gold medalist.


Let the buyer beware.

Let the buyer beware.


Altered state of consciousness. IV. The relationship between the N20-02 experience and the hypnotic experience.


How (and why) patients choose a dentist--and stay with him.


The role of nutrition in prevention of oral disease.


Medical-dentist histories for use with nitrous oxide-oxygen sedation.


Harold C. Sternlicht...interesting Texan.


Caution--patient disputes.

Caution--patient disputes.


Practice management blind spot.

Practice management blind spot.


Wire whimsies.

Wire whimsies.


Childhood acute lymphocytic leukemia. Initial radiological bone involvement and prognosis.


Familial congenital disorder resembling stiff-man syndrome.


Pets and adult leukemia.

Pets and adult leukemia.


Benign epilepsy of children with centro-temporal EEG foci. Prevalence and follow-up study of 40 patients.


Orbital frontial seizures. An unique electroencephalographic and clinical syndrome.


A method of modifying the rapidity of cobalt-induced epileptogenesis in the cat.


Approach to curriculum content and development in a two-year dental hygiene program.


The effects of spreading depression on penicillin-induced epileptiform activity in rat brain.


Evaluation of method of self-teaching laboratory portion of pathology.


Managerial characteristics of dentists. II. Leadership opinion questionnaire.


National Coordinating Agency for accreditation in Canada.


Effects of selection methods on study satisfaction of dental students in Finland.


Continuous-progress education. I. New concept of flexible dental curriculum.


Separately administered dental school libraries.


AFDE awards 74 dental scholarships to disadvantaged minority students.


Dental education in and for developing countries.


Activism, medical student style.

Activism, medical student style.


Survey of articulators used in fixed prosthodontic teaching programs.


Aptitudes and individualization in dental education.


Survey of attitudes on dental licensing procedures: full disclosure?


Substitution of perceptual-motor ability test for chalk carving in Dental Admission Testing Program.


A method for teaching evaluation of scientific articles in the dental literature.


Leukaemia in the Rhodesian African.

Leukaemia in the Rhodesian African.


Sepsis complicating the acute respiratory distress syndrome.


A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.


The aromatic substrate binding site in subtilisin BPN' and its resemblance to chymotrypsin.


The crystal and molecular structure of DIP-inhibited bovine trypsin at2.7Angstrom resolution.


The importance of orientation factors in enzymatic reactions.


Pancreatic trypsin inhibitor (Kunitz). I. Structure and function.


Pancreatic trypsin inhibitor (Kunitz). II. Complexes with proteinases.


Crystallographic studies of chicken triose phosphate isomerase.


Triosephosphate isomerase: isotope studies on the mechanistic pathway.


Tropomyosin crystal dynamics.

Tropomyosin crystal dynamics.


The structure of a calcium-binding protein from carp muscle.


The crystal structure of rhombohedral 2 zinc insulin.


Views on approximation, orbital steering, and enzymatic and model reactions.


X-ray crystallographic studies of concanavalin A.


The 5.5 Angstrom resolution structure of the regulatory enzyme, asparate transcarbamylase.


The role of distortion in the lysozyme mechanism.


Stereochemistry of cooperative effects in hemoglobin.


The effect of removal of C-terminal residues on cooperative interactions in hemoglobin.


Three-dimensional structure of abnormal mutant human hemoglobins.


An allosteric model of hemoglobin.

An allosteric model of hemoglobin.


Coboglobins: cobalt substitution and the nature of the prosthetic group--apoprotein interaction in hemoglobin and myoglobin.


The structures of lamprey and bloodworm hemoglobins in relation to their evolution and function.


The structure of a non-heme iron protein: rubredoxin at 1.5 Angstrom resolution.


The structure of a clostridial flavodoxin, an electron-transferring flavoprotein. 3. An interpretation of an electron-density map at a nominal resolution of 3.25 Angstrom.


Protein structure, ribonuclease-S and nucleotide interactions.


The structure of cytochrome b 5  at 2.0 Angstrom resolution.


Structure of the iron-sulfur cluster in the Chromatius iron protein at 2.25 Angstrom resolution.


Crystal structure of an immunoglobulin molecule by x-ray diffraction and electron microscopy.


X-ray crystallographic studies of the Fab and Fc fragments of human myeloma immunoglobulins.


Crystallographic studies of an IgG immunoglobulin and the Bence-Jones protein from one patient.


An electron-density map of tobacco mosaic virus at 10 Angstrom resolution.


The disk of TMV protein and its relation to the helical and other modes of aggregation.


The mechanism and control of the assembly of tobacco mosaic virus from its RNA and protein disks.


X-ray diffraction studies of the structure of satellite tobacco necrosis virus.


Enzymatic catalysis and the transition state theory of reaction rates: transition state analogs.


Interpretation of the rotation function map of satellite tobacco necrosis virus: octahedral packing of icosahedral particles.


Three-dimensional image reconstructions of some small spherical viruses.


Structure of tomato bushy stunt virus: three-dimensional x-ray diffraction analysis at 30 Angstrom resolution.


Use of  19 F-nuclear magnetic resonance spectroscopy for detection of protein conformation changes: application to lysozyme, ribonuclease and hemoglobin.


Structural studies on the adenovirus hexon.


On the interpretation of solvent proton magnetic relaxation data with particular application to the structure of the active site of Mn-carboxypeptidase A.


X-ray diffraction and nuclear magnetic resonance dispersion studies on derivatives of carboxypeptidase A.


A neutron diffraction analysis of myoglobin. 3. Hydrogen-deuterium bonding in side chains.


The use of a computer-controlled display system in the study of molecular conformations.


Protein crystallography 1971: coming of age.


Construction of space-filling models of proteins using dihedral angles.


-Chymotrypsin: what can we learn about catalysis from x-ray diffraction?


Conformational equilibria and the salt bridge in chymotrypsin.


Spectrophotometric and structural evidence as to the mechanism of portease catalysis at chemical bonding resolution.


The stereochemistry of substrate binding to chymotrypsin A .


Conformational changes and inhibitor binding at the active site of elastase.


Morphological changes in the large arteries in polymyalgia arteritica.


The outlook for the adult with acute leukaemia, 1972.


Polymyalgia arteritica.

Polymyalgia arteritica.


Treatment of acute lymphoblastic leukaemia.


The crisis of hysterectomy.

The crisis of hysterectomy.


Glycogen storage disease, type 8.

Glycogen storage disease, type 8.


Familial effects in schizophrenia and homosexuality.


Psychotherapy with university students.

Psychotherapy with university students.


Allusive thinking and its physiological correlates.


The Royal College of Psychiatrists.

The Royal College of Psychiatrists.


Censorship. 2.

Censorship. 2.


Censorship. 1.

Censorship. 1.


One to bind them?

One to bind them?


On studying depression.

On studying depression.


The foetus as a personality.

The foetus as a personality.


Bone marrow histoplasmosis associated with acute lymphocytic leukemia.


Paradox in prepayment of plaque control. Council on Dental Care Programs.


Electrical safety.

Electrical safety.


Chimpanzee dentistry.

Chimpanzee dentistry.


Guidelines for dental aspects of Health Maintenance Organizations.


Guidelines on use of radiographs in dental care programs.


Johnson Foundation announces 4 million dollar student grant.


Survey of attitudes on dental licensing procedures. Bureau of Economic Research and Statistics.


Official action of the 1972 House of Delegates with respect to the "Survey of attitudes on dental licensing procedures".


Formocresol pulpotomy on (young) permanent teeth.


The dentist, the forensic pathologist, and the identification of human remains.


Indirect laryngoscopy using fiber optics.


Centrifuging pour resins.

Centrifuging pour resins.


Expanded functions training for dental assistants in the Indian Health Service.


The association of Streptococcus mutans with early carious lesions in human teeth.


Hand-Schüller-Christian disease: report of case.


Pedicle graft repair of an endodontic defect: report of case.


Acute anaphylaxis from orally administered penicillin G: report of case.


1971 survey of dental practice. 13. Summary. Bureau of Economic Research and Statistics.


Prevention of bacterial endocarditis. American Heart Association.


Calcifying and keratinizing odontogenic cyst.


A retractor for use in intraoral osteotomies.


Electrocardiographic changes during outpatient oral surgery.


Supraorbital emphysema: report of case.

Supraorbital emphysema: report of case.


Chronic sclerosing osteomyelitis of maxilla and mandible: review of the literature and report of case.


Acute allergic reaction associated with methohexital anesthesia: report of six cases.


A rare allergic reaction to sodium methohexital.


Unilateral submandibular gland swelling after induction of general anesthesia: report of case.


Guillain-Barré syndrome after mandibular surgery: report of case.


Type 3 glycogenosis: atypical enzyme activities in blood cells in two siblings.


Physiological rationale for medical treatment of duodenal ulcer.


Laurence-Moon syndrome: evaluation of endocrinological function and phenotypic concordance and report of cases.


Current aspects of digitalis therapy.

Current aspects of digitalis therapy.


Gallop rhythm.

Gallop rhythm.


Risk disclosure in experimentation.

Risk disclosure in experimentation.


The mental health committee: report of the Subcommittee on the Problem of Rape in the District of Columbia.


Relative weight of the placenta and perinatal mortality. A retrospective clinical and statistical analysis.


Color and form perception in visual information processing.


Reliability of the laser refraction technique for different refractive groups.


Effect of contact lens on cornea and lid of a 10-year wearer.


Polymethylmethacrylate: measures of hydration.


Aspherical deformation of lenses with variable refractive power.


The prevalence of corrective lenses among black and white junior high school students.


Optometric treatment of post-surgical constant exotropia.


Hyperphoria of large magnitude--a case report.


Large type reading materials and their sources.


Using the mouse eye for teaching biomicroscopy.


Regional lung function in patients with mitral stenosis.


Mucosal enzyme activity as a quantitative index of early functional improvement in the management of coeliac disease and other small intestinal diseases.


Asthma and the Brisbane climate.

Asthma and the Brisbane climate.


Cyclophosphamide, cholinesterase and anaesthesia.


Multiple sclerosis and autoimmune diseases.


Hypergastrinaemia due to an excluded gastric antrum: a proposed method for differentiation from the Zollinger ellison syndrome.


Azathioprin nd acute restrictive lung disese.


Amantadine and L-dopa.

Amantadine and L-dopa.


Regional lung function studies in clinical medicine.


Practical and ethical problems in human genetics.


Legal and social policy issues pertaining to recent developments in genetics.


Interpatient variation and significance of plasma levels of chlorpromazine in psychotic patients.


The cardiotoxic effect of lipids in rats pretreated with 9 -fluorocortisol and sodium phosphate.


Enhancement of experimental metastasis by x-ray: a possible mechanism.


Vasectomy--survey and symposium.

Vasectomy--survey and symposium.


Vagaries of renal cell carcinoma.

Vagaries of renal cell carcinoma.


Multiphasic screening--panacea or wasted effort?


Severe depression resembling severe physical illness.


Future technics of refraction.

Future technics of refraction.


Disaster planning can save lives.

Disaster planning can save lives.


To inherit and to possess.

To inherit and to possess.


Effect of radiopaque contrast material on left ventricular end-diastolic pressure.


Hepatic metastases from rectal and colon cancers. Treatment by infusion of 5-fluorouracil into umbilical vein.


Cuneiform osteotomy in treatment of slipped capital femoral epiphysis.


Complications of preoperative omission of long-term drug therapy.


Electrocardiograms of the month.

Electrocardiograms of the month.


Recurrent ventricular fibrillation treated with countershocks, bretylium tosylate, and rapid cardiac pacing.


Aortic ball degeneration with splenic rupture.


Celiac axis compression.

Celiac axis compression.


Methadone maintenance program. A voluntary hospital's experience.


Need for burn-care facilities in New York State.


Sixty-one year old caucasian female with epigastric pain, weight loss and aching of legs for two months.


A more sensitive hemagglutination test for A2 strains of influenza virus.


Issues and quandaries in developing a national program in drug abuse.


The dilemma of the adolescent in a rapidly changing society.


Changing patterns of drug use among adolescents.


Doctors, detectives and drugs.

Doctors, detectives and drugs.


Effect of progesterone on metastases and local recurrences of carcinoma of the uterine corpus.


Chemical and pharmacological aspects of medroxy-progesterone-acetate.


The endocrine activity of gestagens.

The endocrine activity of gestagens.


Plasma levels of progesterone achieved by different routes of administration.


Medroxyprogesterone in the management of primary and recurrent or metastatic uterine adenocarcinoma.


Effect of progesterone on human endometrial carcinoma in different experimental systems.


On the picture of mental health. A psychiatric approach.


Complications associated with prolonged operation and anesthesia.


Head trauma due to falls--a brief comment.


MEDICHEM.

MEDICHEM.


Advices to travelers.

Advices to travelers.


TOXICON.

TOXICON.


Functional and professional salvage of the foot by arthrodesis.


Left-handed helical polynucleotides with D-sugar phosphodiester backbones.


Fc and Fab fragments from IgG 2  human immunoglobulins characterized.


Cation-impermeable inside-out and right-side-out vesicles from human erythrocyte membranes.


Biphasic retention of one-trial learning in a clonal fish (Poecilia formosa).


Membrane characteristics of bursting pacemaker neurones in Aplysia.


Role of the surface sheath in the control of morphogenesis in Dictyostelium discoideum.


Single RNA polymerase binding site isolated.


Membrane transport of proteins.

Membrane transport of proteins.


Globin  -chain synthesis directed by "supernatant" 10S RNA from rabbit reticulocytes.


Haemoglobin synthesis during erythroid maturation in  -thalassaemia.


Processing of adenovirus RNA before release from isolated nuclei. Nuclei isolated from cultured human cells (KB) infected with adenovirus type-2 were used to study events occurring during the adenosine triphosphate-dependent release of viral RNA. When cells were labeled with [(3)H]uridine for 50 min beginning 18 hr after infection, most nuclear viral messenger RNA was in the form of high molecular weight precursors with sedimentation coefficients greater than 28 S. When nuclei were incubated in the presence of ATP and an ATP-generating system, labeled RNA the size of viral mRNA (10-29 S) was released. Cleavage of viral RNA precursor molecules of high molecular weight occurred during incubation of nuclei. The change in size of viral RNA did not require exogenous ATP and occurred before release of RNA from nuclei. This RNA cleavage seems comparable to processing of mRNA in vivo, for discrete viral species were produced. Cleavage was completed after 10 min of incubation but was not the rate-limiting step in the release reaction, which required about 20 min for completion.


Mammalian cells with altered forms of RNA polymerase II. Mutants of Chinese hamster ovary cells that are resistant to alpha-amanitin can be isolated. At least some of these mutants contain an altered form of DNA-dependent RNA polymerase II, as indicated by its resistance to alpha-amanitin. These results indicate that mutation to alpha-amanitin resistance involves a change of a structural gene.


Competition, competitive repulsion, and coexistence. This manuscript is concerned with concepts rather than abstruse details or mathematics. Discussed are: competition; extended competition, proposed for competition in the strict sense, extended and modified by all related interactions including predation, parasitism, disease, and even cooperation, all of which can be "weapons of competition"; competitive repulsion, proposed for the sum of forces that determine spacings, including ecologic spacings, of individuals and populations; Darwin (biotic) equilibriums; competitive extinction, Gause's principle, limited and limiting resources, and single-resource competition; de facto coexistence of competing species, exemplified by green plants competing for sunlight; niche competition; the two concepts of competitive exclusion; devision of resources and of their utilizers; cause and effect in real situations; and niches, niche overlap, and coexistence. Stressed is the complexity of the real world, and the confusion that can and does arise from modeling it too simply.


Enhancement of RNA polymerase activity by a factor released by auxin from plasma membrane. Using recently developed techniques for solubilization of RNA polymerase from soybean chromatin and isolation of plasma membrane fractions from plants we can show the presence of a transcriptional factor specifically released from the membranes by auxin, 2,4-dichlorophenoxyacetic acid. The nonauxin, 3,5-dichlorophenoxyacetic acid, does not release the factor, but subsequent exposure of the membranes to auxin results in its release. Factor activity could not be demonstrated in fractions devoid of plasma membranes. The presence of a regulatory factor for RNA polymerase associated with plant plasma membrane and specifically released by auxin provides a mechanism whereby both rapid growth responses and delayed nuclear changes could be derived from a common auxin receptor site associated with plasma membrane.


Bidirectional transcription and the regulation of Phage lambda repressor synthesis. There are two promoters for transcription of gene cI in phage lambda, the gene that codes for phage repressor. The promoters, called pre and prm, are located on the distal (pre) and proximal (prm) sides of gene cro, which itself is adjacent to cI. Since cI and cro are transcribed in opposite directions, cI transcription initiating at pre gives rise to an antisense transcript of cro, while cI transcription initiating at prm does not. Pre, active after infection of a sensitive cell, is stimulated by products of phage genes cII and cIII, and may be located at the site defined by the mutant cY. Prm is active in an established lysogen. These conclusions are based on measurements of the rates of synthesis of antisense cro RNA, cI RNA, and repressor protein in infected and lysogenic cells. To measure antisense RNA, an assay based on the formation of nuclease-resistant, double-stranded RNA, specific to the cro region, was developed. These results raise the possibility that bidirectional transcription of cro has a regulatory function in phage lambda.


Induction of neuronal functions: acetylcholine-induced acetylcholinesterase activity in mouse neuroblastoma cells. Addition of acetylcholine to growing cultures of mouse neuroblastoma cells induced a 37-fold increase in the specific activity of acetylcholinesterase (EC 3.1.1.7). Morphological changes, consisting of neurite-extensions, were also observed during the logarithmic phase of growth of cells stimulated with acetylcholine. A histochemical procedure for localization of acetylcholinesterase was used with the following results: (a) Cells differentiating by growth inhibition in serum-free medium do not stain positively for acetylcholinesterase, except when they have extended neurites, whereas all cells induced with acetylcholine, with or without neurites, stain positively for the enzyme. (b) The inverse relation between cell growth and induction of enzyme activity was demonstrated in nondividing cells at the center of a colony that do not incorporate thymidine into DNA and that stain positively for acetylcholinesterase, whereas actively dividing cells on the periphery of the colony do not stain for the enzyme. However, by addition of acetylcholine we were able to dissociate inhibition of cell growth from biochemical and morphological differentiation in mouse neuroblastoma cells.