Lanthanide ion-induced isotropic shifts and broadening for nuclear magnetic resonance structural analysis of model membranes. The effects of a series of aquated lanthanide ions on the nuclear magnetic resonance spectrum of phospholipid bilayer suspensions are reported. The ability of these ions to provide a spectral distinction between morphologically exterior resonances and their interior counterparts was confirmed. Measurements of the relative shifting and broadening capabilities of these ions are reported, and their correlation with solid-state magnetic susceptibility anisotropies is shown to implicate a dipolar (pseudocontact) mechanism as the source of this effect. The potential for the use of dipolar shifts as structural probes is discussed and an alternative method using dipolar shifting and broadening reagents simultaneously is presented.


Genic variability and strategies of adaptation in animals. Levels of genic heterozygosity, as measured by surveys of allozymic variation, are much lower in populations of large, mobile animals (most vertebrates) than in those of small, relatively immobile animals (most invertebrates). This difference is not consistent with theories relating variability to population size (species number) or dispersal ability (gene flow), but it is predicted by Levins' theory of adaptive strategies in relation to environmental uncertainty ("grain"). Mobility and degree of homeostatic control apparently are important factors influencing levels of genic heterozygosity in natural populations. The results argue indirectly that at least a major proportion of allozymic variation is maintained by natural selection.


Rates of induction of specific translatable messenger RNAs for ovalbumin and avidin by steroid hormones. In the chick oviduct, injections of estrogen and progesterone induce synthesis of the specific proteins ovalbumin and avidin, respectively. We have studied the rate of induction of the specific messenger RNA molecules for these proteins after a single injection of estrogen or progesterone. The mRNAs were extracted, partially purified, and quantified in vitro in a heterologous protein-synthesizing system. Single injections of estrogen in chicks previously withdrawn from all steroid hormones for 2 weeks led to rapid increases in ovalbumin mRNA with 3 hr, which coincided with increases in the rate of ovalbumin synthesis. Maximal ovalbumin mRNA activity occurred by 18-20 hr. The half-life of the mRNA was estimated to be 8-10 hr and corresponded to the half-life for cessation of intracellular ovalbumin synthesis after a single injection of an estrogen. Similarly, after an injection of progesterone into chicks first treated with estrogen, appearance of avidin mRNA preceded demonstrable accumulation of this specific protein in oviduct cells. The mRNA for avidin was first apparent at 6 hr, and reached maximal concentrations between 18 and 24 hr after injection. These data confirm that both estrogen and progesterone act on oviduct to induce rapid accumulation of specific mRNAs before and coincident with the appearance of the cell-specific induced proteins. The overall results of these experiments are compatible with the hypothesis that the production of mRNA is a rate-limiting step in the steroid hormone-mediated induction of protein synthesis.


The effect of controlled hyperventilation on cerebral blood flow and oxygen uptake in patients with brain lesions.


The syndrome of ordinary grief.

The syndrome of ordinary grief.


Secretion of lithium in human parotid saliva in manic depressive patients treated with lithium carbonate.


The effects of catecholamines, acetylcholine and bradykinin on gingival circulation in dogs.


The contribution of oral minor mucous gland secretions to the volume of whole saliva in man.


The composition of human lip mucous gland secretions.


Significance of gravity on the passage of bolus through the human pharynx.


Actinobolin as an inhibitor of the periodontal syndrome in race rats.


Properties of tongue and jaw movements elicited by stimulation of the orbital gyrus in the cat.


Deciduous incisor teeth of the mouse (Mus musculus).


Formation of glycoside-hydrolases by oral streptococci.


The circadian rhythm of mitotic activity in the incisor pulp and the cornea of Rattus norvegicus.


Responses of oral epithelium to the influence of whisker dermal papillae in the adult rat.


Production of bactericidal concentrations of hydrogen peroxide by Streptococcus sanguis.


Penetration of pit and fissure sealants into conditioned human enamel in vivo.


Human prismless enamel and its influence on sealant penetration.


Morphological evidence for the presence of contractile elements in secretory ameloblasts of the rat.


Possible phagocytosis by keratinocytes: ultrastructural evidence from the study of human oral mucosa in organ culture.


A histochemical investigation into the presence and role of glycogen in human odontogenic cysts and periapical granulomas.


Effect of diet deficient in essential fatty acid on fatty acid composition of enamel and dentine of the rat.


The reduction of the solubility of hydroxyapatite in acid by adsorption of phytate from solution.


Effects of light and darkness on human parotid salivary flow rate and chemical composition.


Negro-Caucasoid differences in permanent tooth emergence at a constant income level.


A (3H)-thymidine autoradiographic study of cell proliferative activity of injured parodontal tissues of 5-week-old mice.


Trace element effects on enamel pigmentation, incisor growth and molar morphology in rats.


Effect of yttrium on dental caries in rats.


Circadian pattern of the use of the incisor teeth by laboratory rats.


Ultrastructure of the attachment device between coccal and filamentous microorganisms in "corn cob" formations of dental plaque.


Prevalence of epilepsy in children.

Prevalence of epilepsy in children.


Long-term prognosis of 150 cases of "West syndrome".


Serum concentrations of free diphenylhydantoin and their relationship to clinical intoxication.


The effects of some anticonvulsant drugs on cobalt-induced epilepsy.


The epileptogenic effect of ouabain (g-strophanthin). Its action on the EEG and cortical morphology.


Effects of penicillin on evoked potentials of excised prepiriform cortex of guinea pig.


Involvement of lymphoid and nonlymphoid cells in the production of beta2-microglobulin-a homologue of the constant domains of IgG.


Equilibrium dialysis of ions in nystatin-treated red cells.


A trial of premixed gases with methoxyfluorane as a possible method of anaesthesia in small animal practice.


Mechanical aid to ventilation in the home: use of volume-limited ventilator and leaking connections.


Irradiation of C.N.S. in leukaemia.

Irradiation of C.N.S. in leukaemia.


Gas-chromatographic measurement of urinary polyamines in cancer patients.


Colony-forming ability of a lymphoid and a myeloid murine leukemia.


The use of a plastic isolator for the prevention of infection in patients with acute leukaemia.


Immunosuppressive drugs and acute leukemia.


Skeletal location of radiation-induced and naturally occurring osteosarcomas in man and dog.


Tumour-associated transplantation antigens of neoplasms induced by a naturally occurring murine sarcoma virus (FBJ-MSV). FBJ osteosarcoma virus (FBJ-MSV) isolated originally from a spontaneously arising osteosarcoma in a CF1 mouse is the only known naturally occurring murine sarcoma virus (MSV). It is unique among strains of MSV in producing primarily sarcomata in mice. The capacity of tumour cells transformed in vivo by this agent to elicit specific transplantation immunity in syngeneic hosts was investigated. A low level of resistance (10(4)-10(5) cells) was consistently induced by implantation of x-irradiated (15,000 rad) tumours or surgical excision of developing subcutaneous grafts. By contrast intraperitoneal inoculation of virus containing cellfree extracts of FBJ-MSV sarcomata was a far less effective immunization procedure. Confirmatory evidence for the antigenicity of these neoplasms was obtained in tests in which preincubation of tumour cells with lymphoid cells from specifically immune donors inhibited in vivo outgrowth of the FBJ-MSV cells in untreated syngeneic recipients. The induction of host resistance to FBJ-MSV cells by immunization with identical and independently-induced FBJ-MSV tumours established that FBJ-MSV cells possess common cell surface antigenic specificities in a manner analogous to those of experimental neoplasms induced by other oncogenic DNA and RNA viruses. Since FBJ-MSV cells release infectious virus it was not possible in this system to establish whether the tumour-rejection antigen was cellular or virion in nature. The antigenic weakness of FBJ-MSV cells in syngeneic hosts is comparable with that of virus-induced murine leukaemias of the Gross (G) or "wild" type subgroup to which category FBJ-MSV also belongs. These features suggest that FBJ-MSV exemplifies naturally occurring sarcomagenic viruses more closely than those of the Friend-Moloney-Rauscher-Graffi (FMRGr) subgroup which in general induce highly antigenic neoplasms.


The rate of mutation of L5178Y asparagine-dependent mouse leukemia cells to asparagine independence and its biological consequences.


Acute myeloid leukemia with two Philadelphia chromosomes in forty-six stemline. Remarks on the karyotypic analysis and chemotherapy.


Leukemia in southern Iran.

Leukemia in southern Iran.


An approach to research.

An approach to research.


The aluminium band provisional splint.

The aluminium band provisional splint.


Congenital intermaxillary fibrous bands.


Periodic observation of the relapse of upper incisors which had been rotated by an appliance.


Occlusion and malocclusion in Lagos.

Occlusion and malocclusion in Lagos.


Facial profiles in different occlusal categories.


Subacute bacterial endocarditis in an edentulous patient.


Pathogenesis of disturbed extraction wounds.


Medical evaluation of the ambulatory oral surgery patient.


Sensitivity to succinylcholine.

Sensitivity to succinylcholine.


Expanded split-thickness mucosal grafts.


Case 2. Part 2. Synovial chondromatosis of the temporomandibular joint.


Changes in mandibular morphology after surgical correction of prognathism: report of case.


An ameloblastoma and a hamartoma of the dental lamina in two siblings.


Bilateral cutaneous sinus tracts of dental etiology: report of case.


A destructive giant cell lesion of the mandible.


Large calculus of the submandibular gland: report of case.


Eosinophilic granuloma of bone: report of case.


Metastatic carcinoma of the mandibular condyle: report of case.


A lipoma in the floor of the mouth: report of case.


Percutaneous drilling technique for upper border wiring of fractures of the angle of the mandible.


Unexpected obstruction of a nasotracheal tube: report of case.


The health and welfare of immigrants.

The health and welfare of immigrants.


Venereal disease: case and contact finding.


Syphilis in pregnancy supervening on yaws: case report.


Bubonic plague.

Bubonic plague.


Placenta percreta causing spontaneous perforation of the uterus: case report.


Bacterial contamination of drip sets.

Bacterial contamination of drip sets.


The economics of the general medical services benefit.


The danger of giving tetracyclines to patients with kidney disease.


Abortion.

Abortion.


Omissions in advertising.

Omissions in advertising.


Hospital resident salaries.

Hospital resident salaries.


Acute leukemia in pregnancy.

Acute leukemia in pregnancy.


Acute dextropropoxyphene hydrochloride (Darvon) poisoning.


Sentics: biocybernetics of emotion communication.


Observations on the aetiology of supernumerary upper incisors in the albino ferret (Mustela putorius).


Tooth development in the albino ferret (Mustela putorius) with special reference to the permanent carnassial.


An autoradiographic investigation of the developing rat periodontal membrane.


Somatotopic organization of the trigeminal ganglion in the rat.


Histochemical disclosure of endogenous and H2O2-dependent reducing enzyme activities in leukocytes and other cytological entities from the human oral cavity.


Deciduous dentition in the rabbit (Oryctolagus cuniculus). A roentgenographic study.


Quantitative microradiography of intact and worn human coronal dentine.


Invertase activity in Streptococcus mutans and Streptococcus sanguis.


A proposed classification for heritable human dentine defects with a description of a new entity.


Changes in Streptococcus mutans and lactobacilli in plaque in relation to the initiation of dental caries in Negro children.


Recovery of Streptococcus mutans and Streptococcus sanguis from a dental explorer after clinical examination of single human teeth.


Effect of castration and androgen supplementation on sialic acid levels in rat submandibular gland.


Reflections on dental education.

Reflections on dental education.


Application of precedence graphs as descriptive tool in development of "independent study" dental curriculum.


Ergonomics: new entity in dental education and research.


Survey of existing mechanisms for faculty governance at AADS member institutions.


Dentist's role as team manager--developing administrative skills.


Influence of elective predental chemistry courses on grades in biochemistry.


Dental management profiles and practice management characteristics.


Correct spelling a vanishing art.

Correct spelling a vanishing art.


II. Audit Report: Dental Education, 1971-72, 1972-73.


Attitudinal differences in senior dental students at University of California and Cairo University, Egypt.


Clinical trial of a new semi-synthetic cephalosporin cephradine upon staphylococci and gonococci.


Measles in Auckland, 1971-1972.

Measles in Auckland, 1971-1972.


Dextran 70 in the prevention of post-operative deep-vein thrombosis with observations on pulmonary embolism: report on a pilot study.


The assessment of abdominal aortic aneurysms.


An electrocardiogram radiotelemetry monitoring system for hospital patients.


The place of fetal heart rate monitoring.


Thrombocytopenic purpura in infectious mononucleosis.


Traumatic liver cyst.

Traumatic liver cyst.


Methadone and opiate addiction again.

Methadone and opiate addiction again.


Medical ethics.

Medical ethics.


Behavioural sciences at Otago.

Behavioural sciences at Otago.


Police offences Act (1927).

Police offences Act (1927).


Cor pulmonale.

Cor pulmonale.


Comments on preventive health--collective and individual responsibility.


Twenty-four year old girl with recurrent abdominal pain.


Thermoregulation by social wasps: behavior and pheromones.


Catecholamines and monoamine oxidase activity in turkeys with high or low blood pressure.


Nitrogen balance, plasma amino acid levels, and amino acid requirements.


The treatment of class II facial deformity. Orthondontic considerations.


The treatment of class II facial deformity. Maxillary operations.


The treatment of class II facial deformity. Segmental surgery.


Oral manifestations of leprosy.

Oral manifestations of leprosy.


Immune concepts and the oral surgeon.

Immune concepts and the oral surgeon.


An unusual complication of lower third molar removal.


Adrenal crisis in a dental patient having systemic corticosteroids.


The adenoameloblastoma.

The adenoameloblastoma.


Coronoid process enlargement.

Coronoid process enlargement.


The production of a bone resorbing factor by dental cysts in vitro.


Perphenazine side-effects presenting in oral surgical practice.


Tuberculosis causing bilateral oroantral fistulae.


Exfoliative cheilitis.

Exfoliative cheilitis.


Overcoming the disadvantages of a halo.

Overcoming the disadvantages of a halo.


Amalgam carrier for retrograde apical fillings.


The effect of erythrose and related compounds on the growth and acid production of streptococci and lactobacilli.


A simple abrasion test for composites.

A simple abrasion test for composites.


Odontodysplasia. A case report.

Odontodysplasia. A case report.


Morphological variations between English population samples.


Cancer Programs in New Jersey.

Cancer Programs in New Jersey.


Radiation legislation.

Radiation legislation.


A Brief look at fissure sealants.

A Brief look at fissure sealants.


Fluoridation commission conclusions.

Fluoridation commission conclusions.


Cherubism. A case report.

Cherubism. A case report.


Sialolith.

Sialolith.


Mechanism of action of pancreozymin and acetylcholine on pancreatic acinar cells.


Basophilic leukaemia in the albino rat and a demonstration of the basopoietin.


Non-synchronized suppression of postnatal activity in non-allelic genes which synthesize the Ggamma chain in human foetal haemoglobin.


Binding of catecholamines to receptors in cultured myocardial cells.


Time-course of phenotypic expression of Escherichia coli gene Z following transgenosis in haploid Lycopersicon esculentum cells.


Quantitative release of live microorganisms from infected macrophages by sodium dodecyl sulphate.


Isolation of the sugar-binding protein from rat taste buds.


What price glory?

What price glory?


Choosing an analgesic medium.

Choosing an analgesic medium.


Guiding occlusal development.

Guiding occlusal development.


Professionals and consumers: antagonists or synergists?


Traumatism of upper incisors.

Traumatism of upper incisors.


Effect of carbon and nitrogen sources on the production of L-asparaginase by Erwinia aroideae.


Effect of salivary supernatant on the glycolytic activity of the bacteria in salivary sediment.


An x-ray line-broadening study of turkey leg tendon.


Phosphoenolpyruvate carboxylase and ammonium metabolism in oral streptococci.


Inhibitory effects on jaw muscle activity of innocuous and noxious stimulation of facial and intraoral sites in man.


Immuno-electrophoretic and chemical analyses of human parotid saliva.


Evaluation of a new transport medium for the preservation of oral streptococci.


Mineralization in the roots of human deciduous teeth demonstrated by tetracycline labelling.


Correlated morphometric and biochemical analysis of gingival tissue in early chronic gingivitis in man.


Histochemical localization of selected dehydrogenases in frozen sections of human dental plaque.


In-vitro culture of periodontium of young adult mouse.


Inbreeding in the Great Tit.

Inbreeding in the Great Tit.


Frequency-dependent sexual selection as a result of variations in fitness at breeding time.


Equilibrium potentials of membrane electrodes. A simple thermodynamic theory of the equilibrium potentials of membrane electrodes is formulated and applied to the glass electrode for measurement of pH. The new formulation assumes the selective adsorption or binding of specific ions on the surface of the membrane which may or may not be permeable to the ion, and includes the conventional derivation based on reversible ion transport across membranes as a special case. To test the theory, a platinum wire was coated with a mixture of stearic acid and methyl-tri-n-octyl-ammonium stearate. When this coated electrode was immersed in aqueous phosphate solution, its potential was found to be a linear function of pH from pH 2 to 12 with a slope equal to the theoretical value of 59.0 mV per pH unit at 24 degrees .


A rat mammary carcinoma in vivo and in vitro: establishment of clonal lines of the tumor. Clonal cell lines from a pituitary hormone-dependent rat mammary carcinoma were established. The growth of these cell lines in vitro is markedly stimulated in the presence of prolactin. The cells grow well in a medium supplemented with fetal-calf serum (generation time: 9-10 hr), but do not grow with calf serum. Fetal-calf serum supports little growth when the serum is subjected to anti-prolactin-affinity chromatography. Gel filtration of fetal-calf serum indicates that the growth stimulatory activity is in a large molecular weight material (close to 100,000), suggesting that prolactin is associated with another serum component. A variant of the original tumor, which does not require hormone for growth, was obtained, and clonal cell lines of this tumor were also established. These cells, in contrast to the hormone-dependent ones, grow well with either fetal-calf serum (with or without anti-prolactin treatment) or calf serum.


Restoration of hypoxanthine phosphoribosyl transferase activity in mouse 1R cells after fusion with chick-embryo fibroblasts. Fusion of the 1R mouse cell, which lacks activity of hypoxanthine phosphoribosyl transferase (EC 2.4.2.8), with chick-embryo fibroblasts yielded progeny cells that survived in hypoxanthine-aminopterin-thymidine selective medium. This property and the failure of the progeny to survive in 8-azaguanine indicated that hypoxanthine phosphoribosyl transferase activity was present. Electrophoretic analysis revealed that the enzyme was of mouse, not chick, origin. These observations are consistent with the operation of a regulator gene responsible for the absence of hypoxanthine phosphoribosyl-transferase activity in the 1R cell and its presence in the progeny.


Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate. Etorphine, the most potent narcotic analgesic known, was labeled with tritium by catalytic exchange. This drug exhibits stereospecific, saturable binding to rat-brain homogenate. At saturation, the stereospecific binding is 0.1-0.15 pmol/mg of protein. Specific binding is inhibited high salt concentrations, sulfhydryl reagents, and proteolytic enzymes, but is unaffected by phospholipases A and C, sodium azide, sodium fluoride, and prostaglandins E(1) and E(2). Competition for binding of [(3)H]etorphine correlates with agonist and antagonist potencies. The stable, stereospecific binding of an active narcotic analgesic supports the existence of opiate receptors.


Purification and properties of ribonuclease H of calf thymus. Ribonuclease H of calf thymus has been purified better than 3000-fold to yield an almost homogeneous preparation. The enzyme, which comprises about 0.03% of the total protein in the initial extract, is a slightly acidic protein (pI = 4.95) of molecular weight of about 64,000, possibly composed of subunits. The enzyme requires a metal ion for activation; the conditions for activation by Mg, Co, and Mn are described. It is inhibited by S-adenosylmethionine. The substrates cleaved were poly(dT).poly(rA) and the DNA-RNA hybrid made from phage f1 DNA; ribosomal RNA was not attacked.


Genetic analysis of developmental stages of the cellular slime mold Dictyostelium purpureum. 71 Mutants of Dictyostelium purpureum, unable to carry out normal development, were isolated. These mutants fall into three phenotypic classes. The mutants of the first class do not aggregate. Those of the second class develop a little further and form conical aggregates. The mutants of the third class progress still further, and the conical aggregates are transformed into finger-shaped masses, but no fruiting bodies are formed. Mutants of each class were able to form fruiting bodies when mixed with mutants of other classes. Pairs of mutants belonging to the same class, however, never responded synergistically. This result indicates the presence of three distinct developmental stages in the process of the fruiting-body formation. Experiments with actinomycin D suggested that genes controlling the developmental process of D. purpureum were divided into three groups which were identical to those identified by the analysis of synergism.


Contact inhibition of movement in the cultures of transformed cells. Results of cell-cell collisions were studied with the aid of time-lapse microcinematography in primary cultures of normal mouse-embryo fibroblast-like cells and in cultures of transformed mouse cells of two types: (a) primary fibroblast-like cells transformed by Moloney mouse sarcoma virus; (b) neoplastic fibroblasts of the CIM strain. Collisions of normal fibroblast-like cells and CIM cells in mixed cultures were also analyzed. Classification of the results of collisions was based on observation of the movements of the active cell edge during the first hour after the moment when this edge had contacted another cell. Three types of collision results were detected: halt of the active edge, overlapping, and underlapping. The relative number of overlappings was not higher and that of halts not lower in the cultures of transformed cells as compared with those of normal cells. Analysis of the collisions of normal fibroblasts with transformed cells gave similar results. Thus, the altered morphology of the cultures of these transformed cells cannot be explained by loss of contact inhibition of movement leading to increased ability of cells to move over the surfaces of other cells after collision.


Conformations of arsanilazotyrosine-248 carboxypeptidase A alpha, beta, gamma, comparison of crystals and solution. The spectra of the alpha, beta, and gamma forms of zinc monoarsanilazotyrosine-248 carboxypeptidase A are indistinguishable. At pH 8.2 their crystals are yellow, while their solutions are red, lambda(max) 510 nm. Absorption and circular dichroism-pH titrations of the modified zinc and apoenzymes demonstrate that the absorption band at 510 nm is due to a complex between arsanilazotyrosine-248 and the active-site zinc atom. Two pK(app) values, 7.7 and 9.5, characterize the formation and dissociation of this arsanilazotyrosine-248.Zn complex. On titrations of the apoenzyme, the absorption band at 510 nm is completely absent at all pH values. Instead, there is a single pK(app), 9.4, due to the ionization of the azophenol, lambda(max) 485 nm. Substitution of other metals for zinc results in analogous intramolecular coordination complexes with absorption maxima and circular dichroism extrema characteristic of the particular metal. Similar data and conclusions have been derived from studies of heterocyclic azophenol.metal complexes. The present studies demonstrate that the conformation of the crystals of all generally available alpha, beta, and gamma forms of the arsanilazoenzyme differs from that of their solutions. The spectra of the modified x-ray crystals, however, differ from those of all other carboxypeptidase forms and crystal habits studied. The internal consistency of their data, their interpretation, and the conclusions of Lipscomb and coworkers [Proc. Nat. Acad. Sci. USA (1972) 69, 2850-2854] are examined. Dissimilar chemical modification or conformation is thought to underlie these differences. The arsanilazotyrosine-248.zinc complex is a sensitive, dynamic probe of environmental conditions. Its response to changes in pH and physical state of the enzyme suggest different orientation of the arsanilazotyrosine-248 side chain in solution from that in the crystal. This finding calls for reexamination of the basis of the substrate-induced conformation change which has been thought to be critical to the mechanism, postulated on the basis of the x-ray structure analysis performed at pH 7.5.


The role of a tyrosyl residue in the mechanism of action of carboxypeptidase B: luminescence studies. The luminescence spectra of carboxypeptidase B indicate specific differences between the zinc and apoenzyme due to the state of tyrosyl residues presumably at the active site. These differences disappear when enzyme-substrate or enzyme-inhibitor complexes are formed, suggesting that they may reflect the interaction of a tyrosyl residue in the native enzyme with the catalytically essential zinc atom. An interpretation of the role of that tyrosyl residue in the mechanism of action of carboxypeptidase B is presented.


Synthesis of globin ribonucleic acid from duck-reticulocyte chromatin in vitro. The proteins of chromatin serve to restrict the transcription of DNA. The relevance of these findings to the control of gene expression is contingent upon the demonstration that this restriction is specific and mirrors the patterns of RNA synthesis observed in vivo. In this study we demonstrate by RNA-DNA hybridization that the vast majority of the chromatin-directed RNA is synthesized from the unique regions of the reticulocyte genome. Furthermore, by use of the DNA complement of globin mRNA as a probe in annealing reactions, de novo synthesis of globin RNA was detected in RNA transcripts from duck reticulocyte chromatin. No globin sequences were detected in similar preparations of RNA in vitro either from liver chromatin or from DNA freed of protein. These results show that the proteins of chromatin serve to restrict transcription in a very specific manner and provide convincing evidence for the existence of transcriptional control factors in eukaryotes.


A differential effect of heavy water on temperature-dependent and temperature-compensated aspects of circadian system of Drosophila pseudoobscura. D(2)O is the only "chemical" agent that consistently affects the frequency of circadian oscillations: its effect is now known to be so widespread and predictable that its action merits closer study as a potential clue to the currently obscure concrete nature of circadian oscillators. The great diversity of D(2)O effects on biological systems in general is briefly reviewed and the need for rejectable hypotheses concerning the action of D(2)O on circadian clocks is stressed because current speculation on its action yields "predictions" expected from almost any hypothesis. We consider the hypothesis that it "diminishes the apparent temperature" of the cell and proceed to test this by examining the effect of D(2)O on temperature-dependent and temperature-compensated aspects of the circadian system in Drosophila. We find these components respond as differentially to D(2)O as they do to temperature; we conclude, however, with a warning that this result may be equivocal if, as we now suspect, the frequency of circadian oscillations is generally homeostatically conserved-not only in the face of temperature change, but change in any variable to which it is sensitive. More crucial tests of the temperature-equivalence hypothesis for D(2)O action are defined.


Delayed removal of N-terminal methionine from nascent globin chains in sickle-cell anemia reticulocytes. Synthetic alphaT1 and betaT1, the N-terminal tryptic peptides of alpha-chain and beta-chain of hemoglobin, and MetalphaT1 and MetbetaT1, peptides in which N-terminal methionyl residues are peptide-bonded to alphaT1 and betaT1, were prepared by the solid-state method of Merrifield. These synthetic peptides were used to establish conditions for chromatographic purification and analysis. When tryptic digests of nascent globin chains from rabbit and sickle-cell anemia reticulocytes incubated with (35)S- and (3)H-labeled amino acids were analyzed, radioactivity not present in tryptic digests of labeled hemoglobin appeared at the elution positions of MetalphaT1 and MetbetaT1. The fraction of nascent chains with N-terminal methionine was higher in sickle-cell anemia reticulocytes than in rabbit reticulocytes. If rate of peptide-chain elongation in polysomes is uniform, nascent human chains must attain a greater length before removal of the initial methionyl residue. Length of nascent chain at time of removal was calculated from two independent sets of data, one obtained from [(35)S]methionine incorporation into MetalphaT1, MetbetaT1, alphaT5, and betaT5, and the other obtained from [(3)H]lysine and [(3)H]valine incorporation into MetbetaT1 and betaT1.


Action of rifamycin derivatives on RNA polymerase of human leukemic lymphocytes. The mechanism of inhibition of human RNA polymerase by four rifamycin derivatives was investigated. Derivative AF/013 (3-formyl rifamycin SV:O-n-octyloxime) with strong hydrophobic side chains prevents the polymerase from binding to DNA and also affects the size of RNA synthesized. Derivative PR/19 (3'-acetyl-1'-benzyl-2'-methylpyrrolo[3,2-c]-4-desoxy-rifamycin SV) only affects RNA synthesis when RNA polymerase has been previously incubated with the drug or when the reaction was performed at high salt concentration [0.14 M (NH(4))(2)-SO(4)]. Our results suggest that these drugs exert their inhibitory actions by binding to the enzyme instead of DNA.


Conformational studies of oxytocin, lysine vasopressin, arginine vasopressin, and arginine vasotocin by carbon-13 nuclear magnetic resonance spectroscopy. Oxytocin, arginine vasopressin, lysine vasopressin, arginine vasotocin, as well as their cyclic and acyclic analogs, were studied by carbon-13 nuclear magnetic resonance spectroscopy in deuterium oxide and deuterated dimethylsulfoxide. Fourier-transformed spectra were obtained at 25.16 MHz. The resonances of all carbon atoms have been assigned in both solvent systems; this includes tentative assignments of the carbonyl carbons. The spectra of arginine vasopressin and lysine vasopressin are essentially identical when compared in D(2)O or dimethylsulfoxide, but they differ from those of oxytocin. The spectrum of arginine vasotocin in D(2)O is intermediate between those of oxytocin and the vasopressins. These spectral differences are not only due to variations in constituent amino acids but are also a reflection of conformational differences of oxytocin, arginine vasotocin, and the vasopressins. All hormones are sensitive to changes in hydrogen ion concentration in both solvents; this was not observed with deamino analogs, which lack the terminal amino group.


Mouse lambda-chain sequences.

Mouse lambda-chain sequences. Amino-acid sequences of the variable regions of three lambda chains produced by plasmacytomas of BALB/c mice are compared. Two are almost certainly identical and one differs from these by three amino acids. These findings extend our earlier conclusion on the relative uniformity of sequences in this type of immunoglobulin light chain. With amino-acid sequence data on two additional lambda chains, eight mouse lambda chains studied to date are indistinguishable and four probably differ from these by one, two, or three amino acids.


Genetic mapping of the inversion loop in bacteriophage Mu DNA. An inversion loop seen in heteroduplex mapping of the DNA of mature Mu phage induced from a lysogen is observed also in defective lambda phage carrying one end of Mu. 14% of the DNA of Mu, including this region, designated the G loop, is shown to be to the right of all known genes in the prophage map. The inhomogeneous ends of Mu are observed as a separate phenomenon and appear in all mutants investigated. The recA and recBC functions of the host are not needed for the inversion responsible for the G loop to take place. Deletions of Mu DNA in the G-loop region have been isolated and are under study.


Acceleration of the rate of deamidation of GlyArgAsnArgGly and of human transferrin by addition of L-ascorbic acid. Experiments on the model peptide, GlyArgAsnArgGly, and the protein, human transferrin, have shown that hydrolytic deamidation of these molecules is markedly accelerated by addition of physiologically significant concentrations of l-ascorbic acid. Since hydrolytic demidation has been suggested as an important timer of biological events, the effects on hydrolytic deamidation of substances that are normally present in living organisms and are subject to nutritional control are of special relevance.


HL-A-linked human immune-response genes. Genetic control of the response to specific natural-product antigens has been documented in three informative families. Families were selected on the basis of probands with tuberculosarcoidosis, chronic cutaneous moniliasis, and rheumatoid arthritis. An increased incidence of delayed cutaneous unresponsiveness was observed in each family. Positive associations were identified between HL-A haplotypes and immediate cutaneous hypersensitivity responses to 5, 8, and 11 of 23 test antigens in the three respective families. HL-A-associated differences in averaged responses of cutaneous hypersensitivity were excluded. These significant associations are consistent with linkage between HL-A haplotypes and genes responsible for the immune response to various natural-product antigens.


Difference between functional and structural integrity of messenger RNA. Messenger RNA molecules that are structurally stable, as measured by their ability to hybridize to DNA, may nevertheless be considerably less stable in retaining their ability to function in protein synthesis. The structure of the majority of the mRNA of phage S13 decays with a half-life of 10.6 +/- 0.5 min. In contrast, much of the function of the mRNA that is involved in synthesis of a capsid protein (product of the F gene) decays rapidly with a half-life of 1.4 +/- 0.8 min; a residual amount of function decays with a half-life of 14.0 +/- 4.0 min. The measurements were made in the presence of rifampicin, which was used to prevent the formation of new mRNA. A proposed model for the functional decay is based on the polycistronic nature of the mRNA. Degradation of the mRNA would proceed in two steps: the first step would be a fast attack at a region near the 5'-terminus of each molecule that would eliminate the function of the proximal message; the second step would be a slow attack on the remaining messenger molecule precipitating a subsequent rapid degradation of the physical structure.


Evaluation of 216 four-year survivors of acute leukemia.


Refractory leukemia treated with cytosine arabinoside and cyclophosphamide.


An immunological approach to the treatment of malignant disease.


Evaluation of dental procedures on hemophilic patients in a comprehensive program for the care of hemophilia. 1.


A preliminary study on the peritubular structure of human dentinal tubules by scanning electron microscopy.


Studies on the antidotal action of drugs. 6. The relation between terpin hydrate compound and nicotine.


Incorporation of sodium acetate-1-14C into fatty acid-14C in the gingiva of scorbutic guinea pigs.


Preservation of palatal mucosa. I. Ultrastructural changes and freezing technique.


Preservation of palatal mucosa. II. A sequential histopathologic healing study.


The periodontium of the human tooth in the scanning electron microscope (stereoscan).


Periodontal distribution of occlusal forces photoelastic study.


The prevalence of root surface caries in selected populations.


Computer analysis of oral hygiene habits.


Experimental giant cell granulomas (tumors) in jaws of albino rats.


The treatment of an unusual case of incipient gingival recession exhibiting a familial tendency: a case report.


Cytologic diagnosis of malignant melanoma.


Presidential address. Twentieth annual scientific meeting, American Society of Cytology.


The effects of radiation upon the cytology of benign and malignant bladder epithelia.


Status of cytology in undergraduate medical education.


Electron microscopic studies of mononuclear cells from DMBA-induced tumors in the rat.


Cytology of synovial fluids.

Cytology of synovial fluids.


Regeneration of the ectocervical epithelium after its destruction by electrocauterization.


Studies on the permeability of human oral mucosa. V. The inflow of water through dehydrating oral mucosa.


Ultrastructural changes in pressure zones of human periodontium incident to orthodontic tooth movement.


The effect of tetracyclines on socket healing.


Pregnancy and fluorine in hard tissues. A preliminary report.


The effect of increasing the morphologic face height in full denture restorations on the width of the intra-articular space in the temporomandibular joint.


Studies on the permeability of human oral mucosa. IV. Regional changes in outflow of water from hydrated and dehydrating oral mucosa.


Harmonization of respirator standards in Europe.


Effect of facial hair on respirator performance.


Histochemistry of early oral cancer.

Histochemistry of early oral cancer.


The dental student--what he expects, how he studies, and how he looks at his professional career.


The objectives of dental practice.

The objectives of dental practice.


Report of working group on objectives of curricula--October, 1972.


The influence of dental practice upon dental teaching.


Dental health service and manpower planning in Eastern Europe.


Methods and techniques for the evaluation of courses.


National dental health survey in England and Wales.


National dental health survey in England and Wales and its implications for dental education.


New types of auxiliaries in Australia.

New types of auxiliaries in Australia.


Global epidemiology and aetiology of oral cancer.


Carcinoma-in-situ of the oral mucosa.

Carcinoma-in-situ of the oral mucosa.


Some observations arising from a survey of undergraduate dental curricula in 26 countries.


Design of a curriculum in view of expected and desirable changes in the practice of dentistry.


Early preventive measures in children suffering from inherent lip and palate clefts.


The general practitioner and preventive orthodontics.


"To treat or not to treat".

"To treat or not to treat".


The role of dental health education and auxillary personnel in the prevention of periodontal disease.


Public health aspects of the prevention of dental caries in children.


Report of the Commission on the Armed Forces Dental Services 1971-1972.


The role of the immune response in the development of periodontal disease.


Elements of dietetics for the general practitioner.


Sugar, sugar substitutes and noncaloric sweetening agents.


Advanced education of dental officers--a survey.


Report of the Commission on Dental Education 1971-72.


Report of the Commission on Classification and Statistics for Oral Conditions 1971-72.


Report of the Commission of Public Dental Health Services 1971-1972.


Annual Report of the Asian Pacific Regional Organization of F.D.I. 1971-1972. The Asian Pacific Dental Federation.


Annual Report of the Commission on Dental Materials, Instruments, Equipment and Therapeutics, 1971-72.


Report of the European Regional Organization of the Federation Dentaire Internationale. June 1971 to October 1972.


Erythroplakia of the mouth and carcinoma-in-situ of the oral mucosa.


Small communities and fluoridation; three case-studies.


Working conditions and satisfaction with one's job in programs of preventive and community dentistry.


Gingival hyperplasia during dilantin-therapy; a survey of 312 patients.


Patterns of utilization of dental services in an urban neighborhood health center.


The sparkle in scientific reporting.

The sparkle in scientific reporting.


The Association in action. 1. Report of the Committee on Manpower and Education.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1973.


The role of host tissue in skin carcinogenesis. An investigation with skin-tumor-resistant and skin-tumor-susceptible mice.


The lumbar disc herniation. A computer-aided analysis of 2,504 operations.


Tentorial notch and adjacent major vessels in carotid angiography.


Professional responsibility in a changing world.


The uses of hypnotically produced emotional responses in therapy.


Schizophrenia or antiphrenia?

Schizophrenia or antiphrenia?


Alcoholism and drug dependence as factors in psychiatric hospital admissions.


The age of ageing.

The age of ageing.


Charting.

Charting.


The dental auxiliary and oxygen-nitrous conscious sedation.


An analysis of a preventive dentistry program.


The time course of functional alterations in degenerating dorsal column afferents to lateral cuneate nucleus.


The new torqued appliance.

The new torqued appliance.


Practice administration and investment for professional people.


Factors influencing calculus formation. I. Study plan and selected screening results.


Ultrastructure of the dental plaque and acquired pellicle formed on the artificial tooth surface (Araldite plate).


Variability of leeway space.

Variability of leeway space.


Differentiation in the presence of bromodeoxyuridine id "all-or-none".


Poly (A)-containing molecules in heterogeneous nuclear RNA of normal PHA-stimulated lymphocytes and acute leukaemia blast cells.


Size of the BUdR sensitive targets for differentiation.


Effect of hypoxia on the change in membrane conductance evoked by illumination in arthropod photoreceptors.


Small proportion of opposite geometric isomer increases potency of synthetic pheromone of oriental fruit moth.


Induction of a specific isoenzyme of glutamate dehydrogenase by ammonia in oat leaves.


X-ray diffraction of muscle labelled with antibody to C-protein.


Electron paramagnetic resonance evidence that copper is complexed in humic acid by the nitrogen of porphyrin groups.


Tetanus toxin inhibits amino acid release from nerve endings in vitro.


Multiple cancers of the oral cavity.

Multiple cancers of the oral cavity.


Replantation of avulsed teeth.

Replantation of avulsed teeth.


Effects of vitamin D on developing bones and teeth.


Endodontic implants. IV.

Endodontic implants. IV.


Maintenance of retained deciduous teeth.


Simplified construction of stable custom clutches for pantographic tracing. II.


Extreme overbite occlusions.

Extreme overbite occlusions.


Rehabilitation. Restoration of a partially edentulous mandible allowing for future denture extension.


Late results of irrigation therapy of infected root canals and chronic periapical periodontal disease.


Rehabilitation. Cosmetic reconstruction of cariously eroded, partially edentulous maxilla allowing for future denture extension.


Resorption of an impacted tooth.

Resorption of an impacted tooth.


Radiation injury of connective tissue. A biochemical investigation with experimental granuloma.


Philadelphia chromosome-negative, lysozyme-positive chronic myeloid leukemia.


Importance of a stable maxillomandibular relation.


Orofacial dyskinesia: effective prosthetic therapy.


A comparative evaluation of masticatory efficiency of fixed and removable restorations replacing mandibular first molars.


Investigation of resistance to stress of screw-threaded crown posts.


Masticatory movements of the jaw measured at angles of approach to the occlusal plane.


A qualitative study of the interface between different dental amalgams and retentive pins.


A technique for the easy removal of tight castings from Dentoform teeth.


Cyanoacrylates in pin retention.

Cyanoacrylates in pin retention.


Cavity treatment with a microbicidal fluoride solution: growth of bacteria and effect on the pulp.


Radiographic interpretation of calcified stylomandibular and stylohyoid ligaments.


Heart-lung reanimator.

Heart-lung reanimator.


Inhibition of post-decapitation convulsions by reserpine.


Evaluation: manually operated infant resuscitators.


Hazard: Ambu baby resuscitator.

Hazard: Ambu baby resuscitator.


Analysis of axoplasmic RNA from invertebrate giant axons.


A wobbly double helix.

A wobbly double helix.


Neuronal responses to 5-hydroxytryptamine resulting from membrane permeability decreases.


Inhibition of haemopoietic colony growth by interferon preparations from different sources.


Anatomical location of cells which mediate contact sensitivity in the lympho nodes and bone marrow.


Changes in aldolase isoenzymes of adipose tissue induced by diabetes and ATP.


Effects of GABA and bicuculline on conductance of crayfish abdominal stretch receptor.


Neonatal 6-hydroxydopamine sympathectomy reduces foot shock-induced suppression of water-licking in normotensive and hypertensive rats.


Foetal antigens cross-reactive with tumour-specific transplantation antigens.


The choice of code words in phage MS2 RNA.


Pharmacological implications of the conformation of the methadone base.


Effect of spinal transection on the metabolism of 5-hydroxyindoles formed in vivo from 3H-tryptophan in the rat spinal cord.


Efficient canine retraction with the universal appliance.


Factors that affect the alignment of the mandibular incisors: a longitudinal study.


Necrotizing mediastinitis secondary to descending cervical cellulitis.


Appendix: some anatomic aspects of the Gow-Gates technique for mandibular anesthesia.


Mandibular conduction anesthesia: a new technique using extraoral landmarks.


Personality and response to treatment of the temporomandibular joint pain dysfunction syndrome.


The influence of hyperthyroidism on dental erosions.


Radiographic changes in the mandible associated with leukemic cell infiltration in a case of acute myelogenous leukemia.


Autosomal recessive pigmented hypomaturation amelogenesis imperfecta. Report of a kindred.


Regional odontodysplasia: an ultrastructural and histochemical study of the soft-tissue calcifications.


Premalignant DNA synthesis in hamster pouch.


Inverted oral papilloma.

Inverted oral papilloma.


Traumatic granuloma of the tongue.

Traumatic granuloma of the tongue.


Combined endodontic-orthodontic treatment of transverse root fractures in the region of the alveolar crest.


An evaluation of a zinc oxide and eugenol cement containing o-ethoxybenzoic acid on the human deciduous dental pulp.


Endodontic litigation.

Endodontic litigation.


Evaluation of an S. S. White Panorex x-ray machine.


Idiopathic internal resorption.

Idiopathic internal resorption.


Foreign bodies in nasal fossae of children.


Foreign body simulating a fracture.

Foreign body simulating a fracture.


A comparative evaluation of topical application and iontophoresis of sodium fluoride for desensitization of hypersensitive dentin.


Self-setting acrylic as an immobilizing agent in mandibular fractures.


Uterine cytology: changes in concept of diagnostic interpretation (1952-1973).


Strictly posterior myocardial infarction. (Case report).


Medullary sponge kidney. (Review of the literature and presentation of four cases).


What's new in psychiatry? Plenty.

What's new in psychiatry? Plenty.


Unusual intra-abdominal calcification.

Unusual intra-abdominal calcification.


Prostaglandins.

Prostaglandins.


Fructose and liver protein synthesis.

Fructose and liver protein synthesis.


Effects of fructose, glucose and glyceraldehyde on the toxicity of ethanol in hyperthyroid rats.


The corticoid, insulin and growth hormone responses to intravenous fructose in men and women.


Effect of sucrose feeding on glucose tolerance.


Metabolism of fructose in diabetes.

Metabolism of fructose in diabetes.


Does dietary fructose affect the control of diabetes in children?


Clinical and metabolic aspects of fructose. Concluding remarks.


Effects of dietary fructose and sucrose on plasma triglyceride metabolism in patients with endogenous hypertriglyceridemia.


Fructose metabolism in adipose tissue.

Fructose metabolism in adipose tissue.


Aspects of fructose metabolism in normal man.


Hepatic accumulation of metabolites after fructose loading.


Fracture of the patella. A study of 422 patellar fractures.


Tomography of the temporomandibular joint. Correlation between tomographic image and histologic sections in a three-dimensional system.


Dental prepayment. Delta Dental Plans Association. DSPIC reaches full capitalization; intensifies admittance efforts to aid Delta system.


Milk and prevention.

Milk and prevention.


Asparaginase in combination chemotherapy for remission induction of childhood acute lymphocytic leukemia.


Delivery of dental services in New Zealand and California. Summary of a report to the California Dental Association and the Southern California Dental Association.


Style, efficiency, and convenience in a home-office.


Effect of pins on some physical characteristics of composite resins.


Development of the ultrasonic toothbrush.


Economic implications of adding two expanded-duty dental assistants to a practice.


Selection of teeth for extraction as an adjunct to orthodontic treatment.


Relationship of bacteremia to toothbrushing in patients with periodontitis.


A four-year study of the utilization of dental assistants with expanded functions.


Pulpal response to pin placement.

Pulpal response to pin placement.


Immediate complete dentures--a starting point.


Vital tooth transplants: report of cases.


Expanded-duty dental practice acts: who knows them?


Infarct of the mandible in sickle cell anemia: report of case.


Use of the American Dental Association Dental Health Care Plan during 1969, 1970, 1971, and 1972. Bureau of Economic Research and Statistics.


Survey of recent dental graduates. I. Profile of respondents. Bureau of Economic Research and Statistics.


Aetna Life & Casualty statement of claim practices and procedures with respect to dental expense benefits.


Course listing for September 1973 through January 1974.


Criteria for a recommended standard. Occupational exposure to beryllium and its compounds.


Central nervous system lesions in childhood leukaemia.


Differences in inducing activity for human bone marrow colonies in normal serum and serum from patients with leukemia.


Comparison of two methods of preventing central nervous system leukemia.


Immunologic response of patients with acute leukemia to platelet transfusions.


Lymphoblastic leukemia with marked eosinophilia: a report of two cases.


Headache with particular relationship to nasopharyngitis.


New life for the elderly.

New life for the elderly.


Advances in psychiatric nursing.

Advances in psychiatric nursing.


Communication.

Communication.


A look at the Briggs Report.

A look at the Briggs Report.


President's address: work reaches fruition.


Fluoride in human saliva after ingestion of aluminium chloride and sodium fluoride or sodium monofluorophosphate.


EMF measurements across hydroxyapatite membranes.


The effects of vitamin A and tetracycline on a mouse tooth anomaly.


Determination of fluoride in superficial enamel biopsies from human teeth by means of gas chromatography.


Variations in measurements of human periapical structures in radiographs.


Electron microscopy of human carious dental enamel.


The re-incorporation in calcified tissues of tetracycline released following its deposition in the bone of rats.


Evidence of intracranial deposits at the onset of myelomonoblastic leukaemia.


Ventilatory function and electrocardiographic pattern of cor pulmonale in pulmonary tuberculosis.


Coarctation of the aorta. A follow-up examination of an operated material.


Estimation of the number of narcotic addicts in an urban area.


Hypercalcemia during the diuretic phase of acute renal failure.


Hepatitis virus B infection in an alcoholic with cirrhosis.


Severe multisystem allergic reaction to sulfisoxazole.


The influence of medical school on selection of career specialties.


A conceptual model for rehabilitation.

A conceptual model for rehabilitation.


The View Box: meningioma.

The View Box: meningioma.


Respiratory acariasis caused by Sternostoma tracheacolum in aviary finches.


Effect of staphylococcal contamination of the bovine udder on milk yield.


Liver fluke, Fasciola hepatica in New Zealand. 2. A slaughterhouse survey.


Infectious bronchitis in New Zealand chickens.


Chronic granular rhinitis (nasal catarrh) of cattle.


Clinical investigations with the Makari tumor skin test in France.


Studies with the Makari tumor skin test in Japan.


Studies with the Makari tumor skin test in the United Kingdom.


The geometric mobility sequence in polyacrylamide gel electrophoresis of polymeric proteins: its significance for polymer geometry and electrophoretic theory.


A new hypothesis on the epidemiology of blastomycosis and the ecology of Blastomyces dermatitidis.


Irradiation of C.N.S. in leukaemia.

Irradiation of C.N.S. in leukaemia.


Assessment of binocular vision utilizing the Pulfrich and Venetian blind effects.


Contact angle measurements on hard contact lenses.


Lighting an examination room to avoid error.


Chemical strengthening of ophthalmic lenses.


Proper selection and testing of laser protective materials.


Myopia and dental caries.

Myopia and dental caries.


A binocular refraction procedure.

A binocular refraction procedure.


The N & N soft contact lens.

The N & N soft contact lens.


Iron kinetics in man: new studies with mouse hemoglobin.


Arsenic, oxymetholone, and leukemia.

Arsenic, oxymetholone, and leukemia.


Minor anesthesia.

Minor anesthesia.


Structure of dinoflagellate chromosomes.


Clinical application of jet injection to comprehensive pain control.


Emergency treatment of adverse effects of intravenous premedicants.


Effects of low-dose x irradiation on the chromosomal non-disjunction in aged mice.


Sex pheromones of two noctuid moths.

Sex pheromones of two noctuid moths.


Characterization of a new lymphoid cell type detected in the irradiated mouse.


The role of the dentist in anesthesia.

The role of the dentist in anesthesia.


Sequential disappearance of cell surface components during dedifferentiation in lens regeneration.


Muscle transplantation in the aetiological elucidation of murine muscular dystrophy.


Cytidine deaminase in human lymphocytes.


Antigibberellins of the Cucurbitaceae.

Antigibberellins of the Cucurbitaceae.


Validity of the quadratic fitness function.


Environmentally induced changes in rRNA gene redundancy.


Purification and sequence of messenger RNA for immunoglobulin light chains.


Amino acid sequence of a beta chain of AII component of adult chicken haemoglobin.


Relation of lysosomal fragility in CLL lymphocytes to PHA reactivity.


Age dependent changes in synaptosome buoyant density.


Molecular conformations of chondroitin-4-sulphate.


Stimulation of release of lipoprotein lipase activity from isolated fat cells by rat serum.


Effects of conductive hearing loss on auditory evoked potentials and audiogenic seizures in mice.


Reversing "sudden death".

Reversing "sudden death".


Topical therapy of burns in children with silver sulfadiazine.


Carcinoma of prostatic origin. Metastatic to cervical lymph nodes.


Acute renal failure. Principles of management.


Large abdominal mass after trauma.

Large abdominal mass after trauma.


Pneumogastrography in early diagnosis of perforated gastroduodenal ulcers.


Spontaneous aortic rupture through atheromatous plaque.


Community committee on child abuse. A step toward better understanding and cooperation.


Death following electroshock.

Death following electroshock.


A survey of predental chemistry.

A survey of predental chemistry.


Dental health education; a challenge to the profession.


Acoustic middle ear reflexes: a sensory-control system.


A one visit pulpotomy technique.

A one visit pulpotomy technique.


A survey of the dental status of partially dentate geriatric patients.


Factors influencing recording centric jaw relation.


The dynamic occlusion.

The dynamic occlusion.


A survey of oral pathology present in 300 patients of geriatric age.


Relative analgesia.

Relative analgesia.


Are you a "prophy queen"?

Are you a "prophy queen"?


Chronic lymphocytic leukaemia associated with acute myelomonocytic leukaemia.


Treatment of acute myeloid leukaemia according to the Hammersmith protocol: preliminary report. A preliminary report is given of a trial of the T.R.A.P. regimen (thioguanine, rubidomycin, cytosine arabinoside, and prednisolone) for the treatment of acute myeloid leukaemia. Out of 27 patients treated 13 (48.1%) obtained complete remission. The treatment was well tolerated and produced especially good results in elderly patients.


Psychological cconsiderations in the treatment of thumbsucking.


Facts on fluoridation.

Facts on fluoridation.


Applied psychology course for dental hygiene students.


Approach for dental auxiliaries to teach dental health.


Fissure sealants: practical notes.

Fissure sealants: practical notes.


Community health centre project.

Community health centre project.


Prevention of central nervous system leukemia by irradiation.


Analgesia for modern dentistry. II.

Analgesia for modern dentistry. II.


Methoxyflurane (penthrane) analgesia in dentistry.


The disjunct partial denture.

The disjunct partial denture.


Diazepam...a comparison with other sedative drugs.


The role of the tonsils in streptococcal throat infection.


Hypnosis through the medium of an interpreter.


An experiment in dream telepathy with "The Grateful Dead".


Dental hygiene faculty: demand, sources of supply and recruitment.


Early diagnosis and the periodontal patient.


The management of furcation involvement.


Endodontic and periodontic inter-relationships.


Maxillo-mandibular surgery for correction of dentofacial deformities. 5. Mandibular retrusion (retrognathia).


Factors related to cholesterol formation in cysts and granulomas.


Using mercury safely.

Using mercury safely.


The supervising dentist; an instrument for implementation of a school dental health program.


Replacement of silver amalgam restorations by 50 dentists during 246 working days.


The characteristics of maturity in dental hygiene.


The one-phase mandibular subperiosteal implant denture; an office procedure.


New evidence that private office care costs less.


The stainless steel crown: a clinical guide.


Dental implantations: a review of the literature.


Disadvantages of HMOs and capitation.

Disadvantages of HMOs and capitation.


Editorial: give and you shall receive.

Editorial: give and you shall receive.


Chemical alterations of enamel surfaces by single and sequential treatment with fluorides.


Maxillary nerve block: a useful technique.


The problem-oriented health record.

The problem-oriented health record.


Case 3, Part 1.

Case 3, Part 1.


Intraoral implantation of methyl methacrylate for the restoration of facial contour in old fractures of the malar complex.


Contact stomatitis associated with a dentifrice. Report of four cases.


Radiolucent lesions in the globulomaxillary region.


Movement of permanent incisors following fracture.


Dentistry in the European Economic Community.


Blue nevi of the oral cavity: review of the literature and report of two cases.


Nasopalatine cyst of unusual size: report of case.


Limitation of mandibular movement secondary to coronoid impingement.


Selective grinding of the dentition as an adjunct to orthodontic therapy.


Traumatic displacement of a tooth into the nasal fossa: report of case.


Ludwig's angina infection: report of case and associated systemic complications.


Pseudoankylosis from fusion of coronoid process and zygomatic arch.


Outward displacement of zygomatic arch fractures.


Human bites: review of the literature and report of case.


The significance of serum studies (SMA-12).


Trabecular adenocarcinoma of salivary gland origin: review of the literature and report of case.


Prostaglandin F and progesterone concentrations in the utero-ovarian venous plasma of the ewe during the oestrous cycle and early pregnancy.


Inhibitors of implantation.

Inhibitors of implantation.


Hormones and contraception in the male and the relative merits of hormonal control and vasectomy.


The maturation of spermatozoa in the human epididymis.


A quest for the elusive chemical male contraceptive.


Gonadotrophins in the ovine oestrous cycle.


Survey of preventive dental services now being provided to the school-age population of Tennessee.


Current regulations on dental x-ray units.


Sealants in caries prevention.

Sealants in caries prevention.


Restoration of chromosome aberrations of irradiated tumor cells by DNA and its precursors.


Providing dental care for the disadvantaged.


Normal processing shrinkage in complete maxillary denture construction.


Intensive American anatomy teaching.

Intensive American anatomy teaching.


The present status of composite resins.

The present status of composite resins.


The use of silver points in root canals should be discouraged.


The dental department of a comprehensive health care program could be self-supporting...fact or fiction.


Stress, some of its relationship to dental disease.


Hysterography and diagnostic curettage in carcinoma of the uterine body. An evaluation of diagnostic value and therapeutic implications in stages I and II. A review of 764 patients who were irradiated for carcinoma of the ut erine body, stages 1 and 2, 5-14 years earlier, was undertaken.  The inv estigation was conducted to determine: a) the value of hysterography and diagnostic curettage for determining the local spread of the tumor; b) the risk of dissemination of the infectious and malignant material by hysterography and  curettage in association with intracravitary radium treatment; and c) whether residual carcinoma frequency and recurrences in the uterus and of metastases to the pelvis changes with the local spread and histologic grade of the tumor making it  useful in treatment planning.  606 patients were examined with curettage and hysterography, and 158 with curettage only.  It was found that hysterography does give more detailed information than curettage as to the uterine extent of the tumor and on cervical involvement, but it does not give information on infiltration into the myometrium.  In 92% of the patients examined by hysterography, no infectious complications occurred.  No infectious complications occurred in 90% of those not examined by hysterography.  The findings indicated that the risk of complication in hysterography in association with radiating therapy is very small.  Patients with highly differentiated inoperable uterine adenocarcinoma appear to require more aggressive irradiation of the primary tumor.  Hysterography is useful in assessing whether the primary uterine tumor also involves the cervix.  Knowledge of the histologic grade of the tumor is useful for planning therapy.


Pathologic considerations associated with partial dentures.


Periodontal treatment for the removable partial prosthesis patient. Another half-century?


Comparison of base metal alloys and Type IV gold alloys for removable partial denture frameworks.


Maintenance of the partially edentulous mouth and care of the denture.


Neighborhood health center--an expensive alternative. Council on Dental Care Programs.


That licensure issue.

That licensure issue.


High blood pressure.

High blood pressure.


Electric pulp testers.

Electric pulp testers.


National licensure--a symposium.

National licensure--a symposium.


Frequency of two mesiobuccal root canals in maxillary permanent first molars.


Nonsurgical therapy for the perforative defect of internal resorption.


A profile of clinical preventive practice.


Processing results with a new dental x-ray monobath.


Expanded-duty assistants: attitudes of Army dentists.


Effective interpersonal and management skills in dentistry.


The etiological factors and clinical implications of pica: report of case.


Repair of fractured incisal angles with an ultraviolet-light-activated fissure sealant and a composite resin: two-year report of 60 cases.


Garré's osteomyelitis of the jaws: a review and report of two cases.


Unsuspected ameloblastoma: report of case.


Growth in population and number of dentists to 1985. Bureau of Economic Research and Statistics.


Survey of recent dental graduates. II. Factors related to selection of a practice location.


Emergency kits. Council on Dental Therapeutics.


Neuropathy in McArdle's syndrome.

Neuropathy in McArdle's syndrome.


The President's address. The crisis.

The President's address. The crisis.


Two orders of priority.

Two orders of priority.


The health of workers: a public health perspective of occupations.


Induction of parturition in cattle with corticosteroids: an analysis of field trials.


Treatment of bovine mastitis with rifamycin SV.


An unusual case of neonatal jaundice in a throughbred foal.


Inhibited development of Haemonchus contortus in naturally acquired infections in sheep.


Weight loss, impaired mentation, and anemia.


Clinico-pathological observations on paramonochlorophenol compounds in endodontics. I. Result of direct application to exposed human vital pulp.


Studies in calcification in the interglobular dentin.


A clinico-pathological study of pulp protection with various indirect pulp capping methods prior to silicate cement filling.


Epidermoid cyst of the upper lip: report of a case.


Pin retained amalgam cores for crowns.

Pin retained amalgam cores for crowns.


Your investments Q/A.

Your investments Q/A.


Practice administration Q/A.

Practice administration Q/A.


Collections ... keep more of your dollar.


Corporate practice ... avoiding the pitfalls. 3.


Work smarter...get home earlier.

Work smarter...get home earlier.


Watch out for leaky tax shelters.

Watch out for leaky tax shelters.


Management aids to help boost your earnings.


Office equipment: the real bargains.

Office equipment: the real bargains.


Occlusion.

Occlusion.


The role of the F.D.I. in international dentistry.


Safety standards in the dental surgery.

Safety standards in the dental surgery.


The development of teeth and jaws in tissue culture.


Diagnosis please. Benign follicular hyperplasia of a submandibular lymph node and chronic sialadenitis.


The dental 'vitality' test and pulp status.


Cancer and the dentist.

Cancer and the dentist.


The periodontal health in Thailand on the basis of available data.


Healing of large chronic periapical rarefying osteitis with suppuration by apicoectomy treatment.


Refractory sideroblastic anemia (chronic erythremic myelosis).


Acceptable levels for breathing resistance of respiratory apparatus.


Dental auxiliaries.

Dental auxiliaries.


Quinsy tonsillectomy: a safe procedure.

Quinsy tonsillectomy: a safe procedure.


The value of routine bone marrow and cerebrospinal fluid cultures in patients with cancer--a negative report.


Your security.

Your security.


Maxillo-mandibular surgery for correction of dentofacial deformities. 6. Apertognathia (open bite).


An examination of root canal anatomy of primary teeth.


Effect of priming on interferon inhibition of con A induced spleen cell blastogenesis.


Possible role of phytohaemagglutinin in Phaseolus vulgaris L.


Serotonin metabolism in rat brain after surgical diversion of the portal venous circulation.


Dopamine antagonism and antischizophrenic potency of neuroleptic drugs.


Two proteins of gene A of psiX174.

Two proteins of gene A of psiX174.


An audiometric method for determining the length of root canals.


Peritonsillar abscess: a rationale for treatment.


Synthesis in vitro of anti-Lepore haemoglobin.


Differential activation of maternal and paternal loci in seed development.


New drugs in New Zealand.

New drugs in New Zealand.


Syphilis and yaws: diagnostic difficulties and case report.


Medical research in a growing community.


Biennial conference of the Medical Association. Rotorua, June 11-16, 1973. An opening address.


Non-consummation of a marriage and its legal effect.


Presidential address.

Presidential address.


Thirteenth memorial oration.

Thirteenth memorial oration.


The New Zealand Hospital Service.

The New Zealand Hospital Service.


Adverse drug reactions in a general hospital.


Prospects for hereditary disease control.


Medical research funding in New Zealand 1952-1972.


The evolving role of the American College of Surgeons in peer review and the PSRO legislation.


Vibrio parahemolyticus in Narragansett Bay.


Misuse of heroin and methadone in the city of Oxford.


Marihuana use among adults in Toronto.

Marihuana use among adults in Toronto.


The heroin overdose as a method of attempted suicide.


High dose methadone maintenance: an evaluation.


Psychological differentiation and the response of opiate addicts to pharmacological treatment.


Drug use among schoolchildren in Helsinki 1970.


Drug taking amongst emotionally disturbed university students.


Psychometric signs of cerebral dysfunction in alcoholics.


Attitude manipulation in restricted environments. IV. Psychologically addicted smokers treated in sensory deprivation.


The effect of noxious subliminal stimuli on the modification of attitudes toward alcoholism: a pilot study.


Alcoholism as a social fact: notes on the sociologist's viewpoint in relation to a proposed study of referral behaviour.


The effect of metronidazole on the human taste threshold to alcohol.


A cross-cultural study of attitudes about marijuana smokers.


The Medical University of South Carolina Tumor Registry.


Strength developed in the joint established between 2 different gypsum--water mixtures.


Concepts of schizophrenia among mental health professionals.


Laparotomy and splenectomy as a routine staging procedure in Hodgkin's disease.


Neurotoxicity and elevated cerebrospinal-fluid methotrexate concentration in meningeal leukemia.


In vivo discontinuous DNA synthesis in Ehrlich ascites tumours.


Riampicin insensitive replication of dimer lambda-dv DNA.


Two proteins are bound to most species of polysomal mRNA.


Mobility of concanavalin A receptors in myelin and synaptic membranes.


Suppression of lymphoma development in tetraparental AKR mouse chimaeras derived from ovum fusion.


Effect of pH and surface charge on cell uptake of auxin.


Decreased beta globin mRNA activity in bone marrow cells in homozygous and heterozygous beta thalassaemia.


Steroid therapy in ophthalmology.

Steroid therapy in ophthalmology.


Iron deficiency and its control in U.S. population.


Diseases and their remedies.

Diseases and their remedies.


Biassociation of superior vena caval obstruction and spinal-cord compression.


Pigmented villonodular synovitis. Localized tumor on dorsum of hand.


Ulcerative radiation dermatitis secondary to radon seeds.


Enamel changes in permanent teeth after trauma to their primary predecessors.


A method for radiographic assessment of periodontal bone support following orthodontic treatment.


Silicate cement in a cell culture system.


Residual mercury and amalgam quantity in conventional and wet techniques.


Leukocyte transfusion therapy for patients with host-defense failure.


Effects of chemotherapeutic agents on cell cycle and cellular proliferation: basic and clinical considerations.


Antagonistic action of alpha haemolytic streptococci on Neisseria elongata.


Studies on mannitol-fermenting strains of Streptococcus bovis.


Serological investigations indicating the existence of tick-borne encephalitis virus foci along the Norwegian coast.


Sensitized sheep red cells as a reactant for Staphylococcus aureus protein A. Methodology and epidemiology with special reference to weakly reacting methicillin-resistant strains.


Sero-typing of mycobacteria by a new technique using antibody globulin adsorbed to staphylococcal protein A.


Mycoplasmosis: experimental seminal vesiculitis electron microscopy of infected tissue.


Human parathyroid adenomata maintained in immunosuppressed mice.


Action of Co and Ni at the frog neuromuscular junction.


X chromosome inactivation in X-linked hypohidrotic ectodermal dysplasia.


Dopamine receptors in cockroach salivary gland cells.


Polyadenylate polymerase from vaccinia virions.


Interferon mediates enhancement of tumour growth and virus-induced sarcomas in mice.


Cellobiose phosphorylase in Fomes annosus.


B chromosomes and chromosome pairing in Lolium perenne X Festuca arundinacea hybrid.


Configuration and conformation of bicuculline, a GABA antagonist.


Analogues of gamma-aminobutyrate on rat hippocampal neurones.


Chloroplast growth and division during the greening of spinach leaf discs.


Repeated DNA synthesized during pachytene in Lilium henryi.


Long-term in vitro culture of leukocyte lines LAHL 1, 2, 3.


Our experience with cytosine arabinoside in the treatment of acute haemoblastoses.


Serum alkaline phosphatase in malignant bone tumours (osteosarcoma, chondrosarcoma, fibrosarcoma, Ewing's sarcoma).


The Dental Service Corporation--a pressing need.


A report on dental care programs. A report on prepayment.


The role of local dental societies in the improvement of television nutritional education.


Reciprocity--when?

Reciprocity--when?


Prognathism--orthodontic and surgical management.


Surgical removal of a nasophalatine cyst. Report of a case.


The diagnostic decision: how do our patients view it?


Letter: applying for licensure in Florida.


Respirator cartridge filter efficiency under cyclic-and steady-flow conditions.


Decreased hepatic histidase activity induced by diphenylhydantoin administration as a cause of decrease in urinary formiminoglutamic acid in rats.


Osteoarthrosis of the mandibular condyle.


The relationship between periodontal disease and a metacarpal bone index.


The effect of friction on the keratinising epithelia of the oral mucosa and skin of rodents.


The selection and properties of materials for dental practice. 6. Dental alloys and associated materials.


Evolution of dentitions: an exhibit.

Evolution of dentitions: an exhibit.


The indefinite article.

The indefinite article.


The career commitment of female dental graduates.


Dyschondroplasia and haemangiomata (Maffucci's syndrome). Report of a case with oral and intracranial lesions.


Radiography and radiology for the dental practitioner. 4. Technique--occlusal and extra-oral radiography, and methods of localisation.


An unusual salivary calculus.

An unusual salivary calculus.


Dental manpower in Tasmania.

Dental manpower in Tasmania.


Nystatin in denture liners--an alternative treatment of denture stomatitis.


The organic films on enamel surfaces. 1. The vestigial enamel organ.


Radiography and radiology for the dental practitioner. 5. The principles of radiographic anatomy.


Influencing community decisions on fluoridation.


Peripheral vascular disease today.

Peripheral vascular disease today.


A critical analysis of induced abortion.


Halothane hepatitis: fact or fallacy.

Halothane hepatitis: fact or fallacy.


Virus-like particles in acute lymphoblastic leukemia.


Human rights: biogenetic frontier and beyond.


Human spleen inhibitor of leukaemic cell growth.


Limited intermaxillary opening--an inherited trait.


Familial occurrence of Bell's palsy.

Familial occurrence of Bell's palsy.


Focal epithelial hyperplasia in an Israeli family.


Hereditary hemorrhagic telangiectasia, Raynaud's disease, and the C.R.S.T. syndrome.


Nevoid basal-cell carcinoma syndrome. Report of a pedigree with electron microscopy of skin lesions.


The transmission of pathologic changes between the pulp and the periodontal structures.


Patent accessory canals: incidence in molar furcation region.


Periapical actinomycosis.

Periapical actinomycosis.


Incidence of bifurcations in mandibular incisors.


A radiopaque internal prosthetic acrylic resin.


Self-induced air emphysema of the face and neck.


Large median palatal cyst.

Large median palatal cyst.


An unusual case of tooth migration.

An unusual case of tooth migration.


Effect of anatomic curvature in real-time intraoral thermography.


Leukemia cutis masquerading as guttate psoriasis.


A new factor in urolithiasis: long-term effects of severe respiratory poliomyelitis.


Dare we compromise with the quality of medical care?


Methyltestosterone in constitutional growth delay and familial short stature.


The management of malignant tumours affecting the maxillary and ethmoidal sinuses.


Further experience with new test of pulmonary function.


Treatment of drug addiction in two different communities. Comparative review.


Computer-assisted medical instruction.

Computer-assisted medical instruction.


Fundamentals of computers and their applications to medicine. Inpatient information system.


Opportunistic infections with Erwinia-like species.


Giant-cell myocarditis.

Giant-cell myocarditis.


Long survival with complete transposition of great vessels.


Ounces of prevention. I.

Ounces of prevention. I.


Community response to free vasectomy.

Community response to free vasectomy.


Overeating and obesity from damage to a noradrenergic system in the brain. A discrete, ascending fiber system that supplies the hypothalamus with most of its noradrenergic terminals was destroyed at midbrain level, both electrolytically and with local injections of 6-hydroxydopamine, a destructive agent specific for catecholaminergic neurons. The result was hyperphagia leading to obesity. Fluorescence histochemical analysis showed that loss of noradrenergic terminals in ventral bundle termination areas such as the hypothalamus was necessary for hyperphagia. Damage to dorsal bundle or dopaminergic projections was not. Prior treatment with desmethylimipramine to selectively block uptake of 6-hydroxydopamine into noradrenergic neurons prevented both hyperphagia and loss of norepinephrine fluorescence. The lesions that produced hyperphagia also reduced the potency of d-amphetamine as an appetite suppressant. It is concluded that this noradrenergic bundle normally mediates suppression of feeding, thereby influences body weight, and serves as a substrate for d-amphetamine-induced loss of appetite.


Dark, localized discolorations in the oral mucous membrane. A histopathologic and microradiographic study.


Studies in dentifrices. VII. Fluoride dentifrices and remineralization of dental enamel surfaces. An in vivo study.


The concentration of zinc in subcellular fractions of malignant melanocytes.


Success of endodontically treated anterior teeth in young and adult patients.


Problems with mechanical ventilators.

Problems with mechanical ventilators.


Endodontic radiographic technics.

Endodontic radiographic technics.


Analytical study of some important hallucinogens by a combined fluorimetric and phosphorimetric method.


Optimum dentistry through oral photography.


Sublingual epidermoid cyst.

Sublingual epidermoid cyst.


Editorial: the new dental service corporation.


Dental cleansing tape.

Dental cleansing tape.


The semantics of "Doctor-Dentist" and other symbolic language.


Oral cancer: an example of a descriptive epidemiologic approach to disease.


Functions of dental auxiliaries.

Functions of dental auxiliaries.


Dummy- and finger-sucking habits with special attention to their significance for facial growth and occlusion. 3. Weaning.


The teaching of endodontics in Scandinavia. Treatment of permanent teeth.


Frequency of malocclusion and need of orthodontic treatment in 10-year old children in Gothenburg.


A pilot-study concerning the relation between manifest anxiety and bite force.


The concentration of copper and zinc in the oral mucous membrane. A neutron activation analysis study.


Stenosed parotid duct.

Stenosed parotid duct.


Distribution of muramidase (N-acetyl muramide glycanohydrolase) from different salivary glands.


Function and dysfunction of the masticatory system in Lapps in northern Finland. Preliminary report of an epidemiological investigation.


Actinomycosis--cervico-facial.

Actinomycosis--cervico-facial.


Effect of a cooked starch solution on the pH of dental plaque.


Psychophysical investigation of bite force. 3. Perceived and physically recorded bite force.


Psychophysical investigation of bite force. 4. A clinical assessment of bite force in patients with full dentures.


Studies in dentifrices. 5. The effects of grinding and non-gringing dentifrices on enamel surfaces. An in vivo study.


Distortion in the pantomogram due to object movement.


Sulcus-extension surgery as preprosthetic treatment in the front region of the lower jaw. A clinical roentgenographic evaluation.


The cephalometric profile in intercuspal and retruded contact position in children with excellent occlusions.


A clinical investigation of bite force and chewing habits in patients with total maxillary denture and partial mandibular denture.


Prolongation of the sucking habit as a result of emotional disturbances. A comparative study of groups of children with and without prolonged sucking habits, with reference to personality traits and to emotionally disturbing or prohibitive factors in the environment.


Prolonged sucking habits related to the child's place in line of siblings.


In what situations are sucking habits practiced?


Tomography in diagnosis of incisive canal cysts.


Apparatus for recording of bruxism during sleep.


Mandibular neck fractures. A clinical and radiographic follow-up study.


Hyoid bone position in relation to head posture.


Endodontic treatment of traumatic root perforations in man. A clinical and roentgenological follow-up study.


Endodontic treatment of resorbtive peripical osteitis with fistula. A clinical and roentgenological follow-up study.


Malignant lymphoma with primary mandibular lesions.


Studies in dentifrices. 6. The inhibitory effect of some grinding and non-grinding fluoride dentifrices on dental caries. Including tests of a new, non-grinding manganese-fluoride dentifrice.


Dimensional stability of a rubber impression material. The effect of storage time prior to pouring of the stone die.


Dummy- and finger-sucking habits with special attention to their significance for facial growth and occlusion. 4. Effect on facial growth and occlusion.


Dummy- and finger-sucking habits with special attention to their significance for facial growth and occlusion. 5. Improvement of malocclusion after termination of the habit.


The predictability of hypersensitivity to anti-tuberculous drugs.


Effect ot trimethoprim on folate metabolism in human bone marrow.


Effect of smoking on gastric acid secretion.


The increased rate of loss, and non-exponential excretion of bile salts in patients with tropical sprue and ileoctomy.


Fatal diarrhoeal disease in Australian aboriginal children.


Acute alcoholic hepatitis in Singapore: a comparison with Western series.


A prospective survey of the incidence of cardiac intoxication with digitalis in patients being admitted to hospital and correlation with serum digoxin levels.


Use of porcine calcitonin in osteoporosis.


Postgraduate medical education for general practitioners.


Hypersensitivity to anti-tuberculous drugs.


Lymphoid tumours of eyelids.

Lymphoid tumours of eyelids.


Spontaneous development of macrophage-like cells in a culture of myeloid leukemia cells.


Giardiasis in young adults.

Giardiasis in young adults.


An epidemiologic study of gonorrhea and cancer of the prostate gland.


Psychological problems in the care of the institutionalized aged: a look at D.C. Village.


A case of severe varicella in an adult.

A case of severe varicella in an adult.


An alternate method of treating chronic fissures-in-ano.


Soft contact lenses in the treatment of corneal disease.


The treatment of seizure disorders.

The treatment of seizure disorders.


Recruitment of the West Virginia medical graduate: recognition and approach to the problem.


Actions of morphine on the segmental reflex of the decerebrate-spinal cat. 1. The actions of morphine were studied on the segmental reflex of the decerebrate-spinal cat. Morphine decreased arterial blood pressure.2. Morphine inhibited mono- and polysynaptic reflexes. The influence of morphine on monosynaptic reflexes was more obvious at stimulation of the dorsal root at a frequency of 12.5 Hz than at 0.5 or 2.5 Hz.3. The total amount of activity recorded from the ventral root after morphine depended on whether or not the evoked reflex was maximal or submaximal.4. These actions of morphine were antagonized by naloxone.


Platelet aggregation induced by arachidonic acid is accompanied by release of potential inflammatory mediators distinct from PGE2 and PGF2.


Erythrocyte pooling and sequestration in enlarged spleens. Estimations of splenic erythrocyte and plasma volume in splenomegalic patients.


Cytogenetic studies during remission of blastic crisis in a patient with chronic myelocytic leukaemia.


Intragastric photography in the postgastrectomy patients.


Air pollution in Taipei city.

Air pollution in Taipei city.


The detection of midline echo shift in intracranial diseases by ultrasonic techniques. A clinical review of 425 cases.


A survey on parasitic infections among aborigines in remote mountain area of Chien-Shih District, Hsinchu County, Taiwan.


Stress ulcer.

Stress ulcer.


Clinicopathological conference. Fifty four year old woman with anemia and splenomegaly for several months.


Radiologic case presentation no. 10.

Radiologic case presentation no. 10.


Investigation of women admitted to hospital with abortion.


A case of transexualism exhibiting intersexuality, having a possible XXY--sex determining mechanism.


Sensory confusion through hypnosis: A technique of rapid patient control during dental treatment.


Excerpts from Criteria for a Recommended Standard--Occupational Exposure to Coke Oven Emissions.


Commentary: the Criteria Document for Coke Oven Emissions.


Anteriovenous shunts and fistulae for haemodialysis. A one year review.


What the non-ophthalmologist physician should know about the eye.


Tracheal stenosis. Warning. Danger.

Tracheal stenosis. Warning. Danger.


W. K. Kellogg Health Sciences Library. MEDLINE.


Febrile convulsions in children.

Febrile convulsions in children.


Transfusion reactions. Their recognition and management.


Ultrastructure of sheep osteosarcoma.

Ultrastructure of sheep osteosarcoma.


Short shafts on wheezy kids. Diet control-fact or fancy?


International Medical Student Organization on Population.


Senior citizen. Grow old along with me, the rest much worse may be.


Canoeing as a hobby.

Canoeing as a hobby.


Environmental influences upon time of arrival at puberty.


Problems of emerging sexuality and their management.


Drug disposition in the fetus and newborn infant.


Organ transplants.

Organ transplants.


Cow's milk allergy: prevalence and manifestations in an unselected series of newborns.


A photographic method of measuring eruption rates of rat mandibular incisors.


In vivo transplantation of the mandibular joint of the rat; an autoradiographic investigation into cellular changes at the condyle.


Submerged human deciduous molars and ankylosis.


Histological and ultrastructural observations on the keratinizing epithelia of the palate of the rat.


Changes in the dentition of the guinea-pig following partial section of the inferior alveolar nerve.


The pore structure of human dental enamel.


Vascular leakage resulting from topical application of endotoxin to the gingiva of the beagle dog.


Oral reflexes elicited by mechanical stimulation of palatal mucosa in the cat.


Manual and oral stereognosis in patients with hypogeusia and hyposmia.


The degree of bilateral symmetry in the distribution of plaque bacteria and dental caries in Wistar rats.


A preliminary report of scanning micrographs on the interglobular space in human dentin.


On the morphology of occlusal grooves of the deciduous teeth and their measurement.


Evaluation of dental procedures on hemophilic patients in a comprehensive program for the care of hemophilia. 2.


Effects of arsenite on incorporation of mevalonate-2-14C into squalene-14C in rabbit dental pulp.


Coronary care in the State of Franklin.

Coronary care in the State of Franklin.


Revival of a Federal Prison Hospital Project: the Federal Center for Correctional Research at Butner, N.C.


Dr. Jerome L. Reeves on the new sexuality.


The breeding performance of ewes after hysterotomy.


The anthelmintic efficiency of haloxon in horses.


The anoestrous syndrome in New Zealand dairy cattle. 1. A preliminary investigation.


Kikuyu poisoning of cattle. 2. Epizootiological aspects.


The significance of inhibition in the parasitic development of abomasal nematodes in New Zealand sheep.


Fungus flora of black and white pepper (Piper nigrum L.).


Refractive index of the cornea as a function of its thickness.


Studies of spectral sensitivity as measured by a procedure of flicker threshold.


Visual effects of subfusional rates of high-intensity intermittent photic stimulation.


Effect of accommodative stimulation on galvanic skin response.


A comparative clinical and microscopic study of conjunctivae among institutionalized aged.


Spectral transmission of a new aviation and skiing filter.


A report on the refitting of successful Griffin naturalens wearers with Bausch & Lomb soflens-tm contact lenses (Polymacon).


A new method for determining the tension set of elastomeric impression materials.


Radiography and radiology for the dental practitioner. 6. The principles of radiographic interpretation.


Tuberculosis of the mandible.

Tuberculosis of the mandible.


Care and maintenance of dental X-ray equipment.


Fluoride in the prevention of dental caries. A tentative cost-benefit analysis.


Malpractice...reducing the odds.

Malpractice...reducing the odds.


The dental firing line. Tabulation.

The dental firing line. Tabulation.


Baby bottle caries. Diagnosis and treatment.


Why third-party dentistry is inevitable. The economic facts of life.


Some patients need a "Dear John" letter.


Denenberg vs. the doctors.

Denenberg vs. the doctors.


How to decode your patient.

How to decode your patient.


So you want to build a building. 3.

So you want to build a building. 3.


Continuing education must be compulsory.


Estate planning: what it's all about.

Estate planning: what it's all about.


How to probate your estate without really dying.


If you died yesterday....

If you died yesterday....


Will your will be done?

Will your will be done?


The last love letter.

The last love letter.


2 cases of pycnodysostosis with special emphasis on maxillo-facial findings.


Radiologic examination of the base of the skull and temporal bone in relation to the facial skeleton.


Radiological examination of the upper jaw in patients with cleft lip, alveolus and palate.


Quantitative isotope diagnostic method of the salivary glands in Sjogren's syndrome.


Diagnostic problems with tumors located in the retromaxillary space.


Isobaric sialography.

Isobaric sialography.


Stereometric cephalometry in the diagnosis and survey of dento-facial relationships.


Instrument sterilisation in Glasgow Dental Hospital with some suggestions for general dental practice.


Sixes and orthodontics.

Sixes and orthodontics.


The optimum fluoride content of domestic salt.


Bilateral impaction of lower third molars in association with bilateral dentigerous cyst formation. A case report.


Transfusions of platelets and white cells obtained from single donors.


Colony-stimulating activity. Association with effect of hemodialysis on neutrophil granulocytes.


Medical education. Tranquility or bedlam.


Incidence of plumbism and pica in accidentally poisoned children.


Treatment of early breast cancer. Survey of surgeons.


Subsequent health of former carriers of hemolytic streptococci.


Central nervous system infections in New York State.


Death during intravenous urography. Overdosage syndrome in young infants.


Role of consultation psychiatry in teaching psychopharmacology in the general hospital.


Hepatic alterations in Hodgkin's disease.


Electrocardiograms of the month.

Electrocardiograms of the month.


Dirofilaria infection. Occurrence in northeastern New York.


Massive hemorrhage and death during treatment with clofibrate and warfarin.


Linguistic exploration in time and space. Medicine-doctor-physician-surgeon.


Women in medicine in New Zealand.

Women in medicine in New Zealand.


The effects of vagotomy on the human pancreas: preliminary communication.


Registered and student psychiatric nurses' opinions about mental illness.


Accident surgery in a small hospital.

Accident surgery in a small hospital.


The use of liberal salt diet in pre-eclamptic toxaemia and essential hypertension with pregnancy.


Acute atropine poisoning from ingestion of Datura rosei.


Tetanus occurring in spite of active immunisation.


Surreptitious vomiting causing severe hypokalemia: case report.


The student and negligence.

The student and negligence.


The thick-file patient in England.

The thick-file patient in England.


Adoption: practical aspects and problems.


Women in medicine.

Women in medicine.


Drug addiction.

Drug addiction.


Abortion.

Abortion.


Infant feeding and speech.

Infant feeding and speech.


Blood alcohol in motorists.

Blood alcohol in motorists.


Irradiation effects.

Irradiation effects.


Words for support.

Words for support.


Familial disseminated sclerosis.

Familial disseminated sclerosis.


The effects of the bite of a spider.

The effects of the bite of a spider.


Gas chromatographic-mass spectrometric isotope dilution determination of N,N-dimethyltryptamine concentrations in normals and psychiatric patients.


Recognition of early peridodontal pathology.


Do we need a political action committee?


Tooth mortality. An analysis of etiological factors.


Psychology of dental persuasion in practice administration.


The Filipino dentist and his chances in America.


Adrenal insufficiency in the dog: two case reports.


Oncocytic adenomatous hyperplasia of the larynx: a case report.


Appointment control in a team practice.

Appointment control in a team practice.


Thoughts in transplantation of teeth and a plan for future studies.


Educational dental cubicle design.

Educational dental cubicle design.


Surgical approach to treatment of arthritic diseases.


Experimental study on abnormal habits and malocclusion--disappearance of finger habits.


Resiratory failure after ventral spinal surgery: a clinical and experimental study.


Pseudoaneurysm after angiography.

Pseudoaneurysm after angiography.


Complications of cardiac pacemakers.

Complications of cardiac pacemakers.


Postoperative abdominal wall necrosis.

Postoperative abdominal wall necrosis.


Primary carcinoma of the vagina. Case report and review of the literature.


Sporotrichosis of the thumb. A case report.


Are women's fashions necessary? Reflections following a visit to the People's Republic of China.


Azotemic malignant hypertension: clinical course and survival with vigorous anti-hypertensive regimen and intermittent dialysis.


What the government bestows the government can take away.


Hasty health.

Hasty health.


Denial of insurance benefits.

Denial of insurance benefits.


What happened to the fine art of consultation?


Membrane expansion by vinblastine and strychnine.


Health care, human rights and government intervention: a critical appraisal.


Needed: a rational approach to preventive dentistry.


A practical and economical correction of a lower protrusive denture.


Minnesota medical information service.

Minnesota medical information service.


Update on the multi-state public information program.


New Minnesota dental school will meet critical needs.


Kikuyu poisoning of cattle. 1. Clinical and pathological findings.


Purposes of World Veterinary Congresses.


Values for certain blood and urine constituents of normal young lambs.


Plasma mannosidase activity as a means of detecting mannosidosis heterozygotes.


Salivary enzymes and oral health.

Salivary enzymes and oral health.


Sickle cell anemia.

Sickle cell anemia.


Life insurance facts for dental students and dentists.


Organ distribution of the 99mTc-labeled white cells.