Effect of aflatoxin on germination and growth of lettuce. The relative susceptibility of 30 cultivars of lettuce to inhibition by aflatoxin was studied. Seed germination was not inhibited by concentrations as high as 1,000 mug/ml in cultivar Imperial 44 or by 100 mug/ml in the remaining cultivars. Hypocotyl elongation was inhibited by 46 to 68% at a concentration of 100 mug of aflatoxin per ml. Seedlings exposed to aflatoxin did not become chlorotic. The similarity between the morphological reaction of plants to coumarin and aflatoxin suggests a common mode of action, but further studies of the physiological basis for the inhibitory reactions induced by these compounds will be necessary before such conclusions will be valid.


Effect of phosphate and other anions on trimethylarsine formation by Candida humicola. Phosphate inhibited the formation of trimethylarsine from arsenite, arsenate, and monomethylarsonate, but not from dimethylarsinate, by growing cultures of Candida humicola. Phosphite suppressed trimethylarsine production by growing cultures from monomethylarsonate but not from arsenate and dimethylarsinate, and hypophosphite caused a temporary inhibition of both proliferation and the conversion of these three arsenic sources to trimethylarsine. Resting cells of C. humicola derived from cultures grown in arsenic-free media generated the volatile arsenical only after a lag phase. High antimonate concentrations reduced the rate of conversion of arsenate to trimethylarsine by resting cells, but nitrate was without effect.


Synthesis of glycols by microbial transformation of some monocyclic terpenes. The transformation of three monocyclic terpenes by three soil microorganisms have been studied. The organisms were isolated on, and grew rapidly in, mineral salts medium containing the appropriate terpene substrates as sole carbon sources. These organisms belong to the class Fungi Imperfecti, and two of them have been tentatively identified as Cladosporium species. A Cladosporium species designated T(1) was isolated from terpene-soaked soil, using 1-menthene as the sole source of carbon. The major catabolic product isolated from the growth medium of this organism was found to be a cyclic 1,2-diol identified as trans-p-methane-1,2-diol. A similar but biochemically distinct Cladosporium sp. designated T(7) was isolated on D-limonene. After growth, the medium of this organism contained 1.5 g/liter of the analogous product, trans-limonene-1,2-diol. Minor quantities of the corresponding cis-1,2-diol were also isolated. The third organism, designated as laboratory culture T(8), was isolated on 3-menthene and yielded a diol identified as trans-p-menthane-3,4-diol. From these results it is concluded that the formation of diols is a common intermediate in the fungal metabolism of monocyclic terpenes.


Optimum temperature for enterotoxin production by Staphylococcus aureus S-6 and 137 in liquid medium. The temperature for maximum toxin yield by Staphylococcus aureus S-6 and 137 in liquid medium cultured under aerobic conditions was determined to be 40 C.


Morphological, biochemical, and growth characteristics of pseudomonas cepacia from distilled water. Studies were conducted on three strains of Pseudomonas cepacia isolated and maintained in distilled water and on a laboratory-subcultured strain transferred to distilled water. Optimum growth rates and maximum population yields of the four strains in distilled water were obtained at 37 C, although high population levels (10(6)-10(7)/ml) were reached and maintained over extended incubation periods at temperatures from 18 C to 42 C. Two strains were able to grow in distilled water at temperatures ranging from 12 C to 48 C and to survive 48 h and 21 days at 50 C and 10 C, respectively. Cells from distilled water cultures inoculated into Trypticase soy broth showed an immediate two- to three-log drop at upper and lower temperature limits; survivors were able to initiate logarithmic growth. Results obtained in morphological, biochemical, and antibiotic tests affirmed the strain differences noted in growth studies.


Magnesium metabolism in the laying fowl.


Effects of different light regimes on the sexual maturation of the Fayoumi fowl.


Diencephalic stimulation and mouth movements in the chicken.


Biological fly control in deep-pit poultry houses.


The micro-fauna of Californian-system poultry houses in Britain.


The expanded role of the nurse: a joint statement of CNA-CMA.


What will happen to Mr. Lang?

What will happen to Mr. Lang?


Idiopathic edema.

Idiopathic edema.


The influence of cholesterol on the activity of phospholipids in blood coagulation: requirement for a liquid-crystalline lipid phase.


Enzyme reactions in a membrane model. 1. A new technique to study enzyme reactions in monolayers.


The clinical pharmacology of pentazocine.


Paradoxical quantitative electroencephalographic changes in rats stressed osmotically.


Drug prescribing--therapy or threat.

Drug prescribing--therapy or threat.


Postoperative pain and its management.

Postoperative pain and its management.


Intraepidermal squamous cell carcinoma (Bowen's disease) of the nail bed.


HMO: the way to go?

HMO: the way to go?


Abortion in New Zealand.

Abortion in New Zealand.


Postsurgical signs of systemic disease. A case report.


Motivational factors and socio-economic characteristics of vasectomized males.


Family planning in Yugoslavia with special reference to the province of Vojvodina.


Urban-rural differences in the relationship between women's employment and fertility: a preliminary study. A statistical study of data from the Egyptian census for 1960 points up the influence of the employment of women on their fertility.  Results show that the child/woman ratio rises with the level of female employment in the rural areas, but falls as the level of employment rises in the urban areas.  Subject to confirmation by more detailed methods, it seems that, in urban areas, provision of opportunities for women to work is of major importance in attempting to reduce national fertility levels, but this will have the opposite effect to what is intended in rural areas.  Rural and urban fertility levels appear to be similar at a low level of economic activity; however, when this economic activity surpasses 10%, a noticeable fertility differential appears.  Industrial or commercial work opportunities change a woman's pattern of living, and are essential to the permanent lowering of fertility to replacement levels.


The social impact of human reproduction.


CIBA foundation symposium. Legal and other aspects of artificial insemination by donor (AID) and embryo transfer.


Biosocial aspects of life in Britain. The effects of modern living.


Biosocial aspects of life in Britain. Nature and distribution of genetic abnormalities.


Biosocial aspects of life in Britain. Social mobility and the genetic structure of populations.


Biosocial aspects of life in Britain. Biological effects of current patterns of occupation.


Biosocial aspects of life in Britain. The geography of life and death.


Conditional mutants in Chlamydomonas reinhardtii blocked in the vegetative cell cycle. I. An analysis of cell cycle block points. Conditional "cycle-blocked" (cb) mutants of Chlamydomonas reinhardtii have been detected and isolated. These mutants exhibit normal vegetative growth at permissive temperature but are unable to complete a cell cycle (or a specified number of cell cycles) at restrictive temperature. A simple technique has been devised to determine the cell cycle stage in each mutant when the defective gene product, which ultimately affects cell division, completes its function. This stage is called the "block point", and is determined by scoring the residual cell division in an exponentially growing population after shift to temperature restrictive conditions. In the cb mutants isolated so far, block points representing many stages throughout the cell cycle have been found. Two categories of cb mutants are described here: one set which prevents the subsequent cell division when the cell encounters the block point after a shift to restrictive temperature, and another set which permits an additional round of cell division after the block point is encountered. The general applicability of block point analysis to other cell systems is presented.


Ultrastructural changes in the mitochondria of cerebellar Purkinje cells of nervous mutant mice. The maturation of cerebellar Purkinje cells of normal and nervous (nr/nr) mutant mice has been studied by light and electron microscopy. In the mutant, 90% of Purkinje cells selectively degenerate between postnatal days 23 and 50. Losses are greater in lateral than medial regions. Other cerebellar neurons appear normal. The first morphological abnormality recognized is the presence of rounded mitochondria in perikarya of some Purkinje cells of the mutant at 9 days after birth. By 15 days, all nr/nr Purkinje cells contain spherical mitochondria and begin to deviate from the normal maturational sequence. Elaboration of the extensive dendritic tree halts midway and newly formed axon collateral fibers degenerate. In the perikaryon, the basal polysomal accumulation and climbing fiber-somatic spine synapses are sometimes abnormally retained. Cisternae of the Golgi apparatus and rough endoplasmic reticulum cease to form aligned stacks, and decrease in number, while polysomes dissociate into free ribosomes. These changes are progressive, culminating in cell death. Although every nr/nr Purkinje cell demonstrates spherical mitochondria, some cells survive the critical period, retain a near-normal complement of organelles, and reacquire normal-appearing mitochondria. The disorder appears intrinsic to Purkinje cells since all major classes of synapses were identified before cell death.


Repetitive procurement of mature gametes from individual sea stars and sea urchins.


The organization and projections of the paleostriatal complex in the pigeon (Columba livia).


Isolation of cytoplasmic and chloroplast ribosomes and their dissociation into active subunits from Chlamydomonas reinhardtii. A mixture of cytoplasmic (80S) and chloroplast (70S) ribosomes from Chlamydomonas reinhardtii was freed of contaminating membranes by sedimentation of the postmitochondrial supernatant through a layer of 1.87 M sucrose. The purified ribosomes were separated into 80S and 70S fractions by centrifugation at a relatively low speed on a 10-40% sucrose gradient containing 25 mM KCl and 5 mM MgCl(2). Both the 80S and 70S ribosomes were dissociated into compact subunits by centrifugations in 5-20% high-salt sucrose gradients. The dissociations of both ribosomal species under these conditions were not affected by the addition of puromycin, indicating that the ribosomes as isolated were devoid of nascent chains. Subunits derived from the 80S ribosomes had apparent sedimentation coefficients of 57S and 37S whereas those from the 70S ribosomes had apparent sedimentation coefficients of 50S and 33S. In the presence of polyuridylic acid and cofactors, the 80S and 70S ribosomes incorporated [(14)C]phenylalanine into material insoluble in hot TCA. The requirements for incorporation were found to be similar to those described for eukaryotic and prokaryotic ribosomes. Experiments with antibiotics showed that the activity of the 80S ribosomes was sensitive to cycloheximide, whereas that of the 70S ribosomes was inhibited by streptomycin. The isolated subunits, when mixed together in an incorporation medium, were also active in the polymerization of phenylalanine in vitro.


Some factors affecting C 14 -acetate incorporation into polyunsaturated fatty acids of skin.


Genetic control of two esterase enzymes in Peromyscus leucopus.


Chromium-amino acid conjugates as elicitors in chromium-sensitized guinea pigs.


Conformational changes in the -fibrous protein of epidermis.


Effects of vasopressin on sweat rate and composition in patients with diabetes insipidus and normal controls.


Additional data for linkage group X of the German cockroach.


Genetics of rose, an allele of the white locus in a mosguito.


Time course of lateral inhibition in the human visual system.


Disassembly of melanosomes in detergents.


Synthesis of 2-aminomethylpyrroles and related lactams.


The Canadian hairless of Sphinx cat.

The Canadian hairless of Sphinx cat.


C-glycosyl nucleosides. II. A facile synthesis of derivatives of 2,5-anhydro-D-allose.


C-glycosyl nucleosides. 3. A facile synthesis of the nucleoside antibiotic showdomycin.


New alkaloids and related artifacts from Cyclea peltata.


Chromosome complement of Zaprionus multistriatus.


The isolation and structural elucidation of liatrin, a novel antileukemic sesquiterpene lactone from Liatris chapmanii.


A third Donald Duck beak anomaly in the fowl.


Nor steroids. X. Synthesis of A-nor steroids via the Dieckmann condensation.


DDT-induced chromosomal damage in mice.

DDT-induced chromosomal damage in mice.


A new prognostic score and clinical evaluation system for cystic fibrosis.


Possible pathogenetic factors in neonatal hypocalcemia of prematurity. The role of gestation, hyperphosphatemia, hypomagnesemia, urinary calcium loss, and parathormone responsiveness.


Glycemic response to 24 hour fast in normal children and children with ketotic hypoglycemia.


Erythrocyte and leukocyte phosphoglycerate kinase deficiency with neurologic disease.


A familial syndrome of deafness, alopecia, and hypogonadism.


A syndrome characterized by congenital ichthyosis with atrophy, mental retardation, dwarfism, and generalized aminoaciduria.


Inorganic phosphate (laxative) poisoning resulting in tetany in an infant.


Coma in an infant due to hypertonic sodium phosphate medication.


Glucose disappearance rate in neonatal infection.


Normal development in an infant of a mother with phenylketonuria.


Measurement of blood pressure in the brachial and posterior tibial arteries using the Coppler method.


Systemic cyclopentolate (Cyclogyl) toxicity in the newborn infant.


Adverse reactions to drugs: a clinicopathologic survey of 200 infants and children.


Serum alkaline phosphatase activity during adolescence.


Metabolic alkalosis and salt depletion in cystic fibrosis.


Further speculation on the pathogenesis of Leigh's encephalomyelopathy.


Hemoglobin and hematocrit values: what is normal?


Survival of an infant of a mother dependent upon hemodialysis.


Serum levels of digoxin.

Serum levels of digoxin.


Ketotic hypoglycemia. A tale (tail) of Gauss?


Identical progression of juvenile hereditary nephronophthisis in monozygotic twins.


Meningococcal purpura: report of 19 patients treated with heparin.


Circulating fibrin in meningococcemia.

Circulating fibrin in meningococcemia.


Intellectual deficits in children born with subclinical congenital toxoplasmosis: a preliminary report.


Measles IgM response during reinfection of previously vaccinated children.


A clinical and serologic study of 103 children with measles vaccine failure.


Possible relationship between spontaneous hypoglycemia and the "maternal deprivation syndrome": case reports.


Iron deficiency anemia and scholastic achievement in young adolescents.


Changes in total, nondiffusible, and diffusible plasma zinc and copper during infancy.


Serum ionized calcium valves in relation to exchange transfusion.


Supravalvular pulmonary stenosis.

Supravalvular pulmonary stenosis.


Hemoglobin levels according to age, race, and transferrin saturation in preschool children of comparable socioeconomic status.


Nitroblue tetrazolium dye test and differential diagnosis of meningitis.


Congenital lobar emphysema documented by serial roentgenograms.


Hemophilia home transfusion program: effect of cryoprecipitate utilization.


Severe rickets in infancy and childhood in Ethiopia.


Hepatosplenomegaly, pancytopenia, and fever.


Office screening for bacteriuria in infants: collection of the voided specimen by the parent at home.


Need for smallpox vaccination in high-risk groups.


Screening tests for sugar malabsorption.


Heparin therapy in acute meningococcemia.


Age-related changes in copper and the biological transport of copper: a commentary.


Failures of protection by measles vaccine. Insufficient immunization is the major factor accounting for the failure to eradicate measles in the US; over 70,000 measles cases were reported in 1971, predominantly in previously vaccinated children.  4 reasons have been suggested for these apparent vaccine failures:  1) improper storage or handling of vaccine, leading to inactivation of the live virus; 2) inhibition of the active response to live virus by maternally transmitted or artificially administered passive antibody; 3) a 5% seroconversion failure rate; and 4) development in some children of modified illness and a secondary type of antibody response.  If a 10% failure rate is assumed for a given population, 7% of the vaccinees will be in the primary nonresponse category and 3% may be considered to have responded originaly but to have lost their immunity.  All children vaccinated before the age of 1 year should be revaccinated.  An additional 5-15% of children are in need of a booster; however, until a skin test for immunity is developed, it is not practical to test or revaccinate every child.


Population and politics.

Population and politics.


pH-partition behavior of amino acid-like  -lactam antibiotics.


GLC assay for 5-fluorouracil in biological fluids.


Pharmacokinetics of trichloroethanol and metabolites and interconversions among variously referenced pharmacokinetic parameters.


Kinetics of dehydration and isomerization of prostaglandins E 1  and E 2 .


Ergoline alkaloidal constituents of Hawaiian baby wood rose, Argyreia nervosa (Burm. f.) Bojer.


Clindamycin dose-bioavailability relationships.


UV spectrophotometric method for determination of phenacetin in biological specimens.


Microcapsules. XIV. Effects of membrane materials and viscosity of aqueous phase on permeability of polyamide microcapsules toward electrolytes.


Drug permeation through membranes. I. Effect of various substances on amobarbital permeation through polydimethylsiloxane.


Relationship between CNS depressant and enzyme inhibitory properties of substituted quinazolone 1,3,4-oxadiazoles.


Solubility and dissolution of triamcinolone acetonide.


Preformulation studies. I. Molindone hydrochloride.


Colorimetric determination of aromatic compounds by hydroxylation.


Trichloroacetic acid-induced binding of phenylthiourea to erythrocytes.


Kinetics of synthesis of d 4 -succinic anhydride from succinic anhydride and d 1 -acetic acid.


Prazepam metabolism in the rat.

Prazepam metabolism in the rat.


Structure side-effect sorting of drugs. I. Extrapyramidal syndrome.


Interaction of dextroamphetamine sulfate with dextrates in solution.


UV spectrophotometric analysis of aminobenzoic acid tablets.


Potentiometric determination of overlapping dissociation constants.


Fluorometric determination of epinephrine in low dosage injections and in lidocaine hydrochloride-epinephrine combinations.


Design and evaluation of a rotating filter-stationary basket in vitro dissolution test apparatus. I. Fixed fluid volume system.


Phytochemical investigation of Convolvulus arvensis (Convolvulaceae).


Transport cell for examining solute transfer across biological membranes.


Biochemical interactions of dimethyl sulfoxide. I. Respiratory inhibition.


Effect of vehicle viscosity and an anticholinergic agent on bioavailability of a poorly absorbed drug (phenolsulfonphthalein) in man.


Flowmeter for pharmaceutical powders.

Flowmeter for pharmaceutical powders.


Identification of trimethoprim 3-oxide as a new urinary metabolite of trimethoprim in man.


Participation of micelle at crystal-solution interface in rate-determining step for cholesterol gallstone dissolution in unsaturated bile media.


OTC's: end the dual standard.

OTC's: end the dual standard.


Product dissolution methods.

Product dissolution methods.


Bleeding after snakebite.

Bleeding after snakebite.


Education for primary doctoring.

Education for primary doctoring.


Health information in the mass media: the case of chorionic gonadotropin and obesity.


Lithium as a prophylactic agent in recurring affective disorders.


Sickness absence. An analysis of the problem.


A survey of amputations for degenerative vascular disease.


Gallbladder disease and the heart.

Gallbladder disease and the heart.


Review of maternal deaths in New South Wales from eclampsia and severe preeclampsia--1961 to 1969.


Ovarian tumours in pregnancy.

Ovarian tumours in pregnancy.


Psychiatric sequelae to legal abortion in South Australia.


Haemoglobin D Punjab in a European family in Australia.


Bone-marrow depression in childhood.

Bone-marrow depression in childhood.


Practical renal physiology with an added incentive.


The effect of postmaturity on the developing child.


Mental illness as a metaphor.

Mental illness as a metaphor.


Observations on lake sediments using fallout  137 Cs as a tracer.


Crystal structure elucidation by the Crystal Data Centre.


Cell-mediated "immunostimulation" induced by mammary tumour virus-free Balb-c mammary tumours.


RNA in coliphage T5.

RNA in coliphage T5.


Chromosome pairing.

Chromosome pairing.


Senescence of human cells in culture.

Senescence of human cells in culture.


Circadian variation of the lethality of methadone.


Liquid crystals in human bile.

Liquid crystals in human bile.


Toxicology of fluoro-olefins.

Toxicology of fluoro-olefins.


Are mosquitoes monogamous?

Are mosquitoes monogamous?


Inhibition of lectins by antifreeze glycoproteins from an Antarctic fish.


Gestation period for Australopithecus.

Gestation period for Australopithecus.


Measurement of the diffusion coefficient in the concentrated phases of the soap-water system by nuclear magnetic resonance.


Spotting the smallpox.

Spotting the smallpox.


Carcinomatosis.

Carcinomatosis.


Iron deficiency anaemia.

Iron deficiency anaemia.


Your specialist course.

Your specialist course.


A multidisciplinary approach to psychiatric nursing.


Psychiatry or people.

Psychiatry or people.


Teach-in. Joint Board of Clinical Nursing Studies. 1. The philosophy.


Aspects of community care.

Aspects of community care.


Teach-in. Joint Board of Clinical Nursing Studies. 2. Curriculum planning.


Comparison of the accuracy of different types of dissolution rate methods.


Pimozide (orap, R 6238) in residual schizophrenia. A clinical evaluation with long-term double-blind follow-up.


Attitudes of psychiatric patients towards different movement situations in movement therapy.


Agenesis of the corpus callosum, chorioretinopathy and infantile spasms (Aicardi syndrome).


Monoamine metabolism and depression in Parkinson patients.


Meditations on the future of clinical neurology.


The epimeric 20-hydroperoxy-5-pregnen-3 -ols: thermal and enzymatic decomposition.


Effect of estradiol on the metabolism of testosterone by rat prostate.


The effect of human chorionic gonadotropin on plasma steroid levels in young and old men.


Competitive protein-binding assay of estrone, estradiol-17  or estradiol-17  in human or ruminant plasma.


Characterization of an androgen binding protein (ABP) in rat testis and epididymis.


Towards an ecdysone synthesis. 20 -acetoxy-5 -pregna-2,7-dien-6-one.


Hearing defects in cystic fibrosis.

Hearing defects in cystic fibrosis.


The Lesch-Nyhan syndrome. Metabolic studies during administration of adenine.


Arthro-dento-osteo dysplasia (Hajdu-Cheney syndrome). Review of a genetic "acro-osteolysis" syndrome.


Animal and vegetable fats in milk replacers for veal calves. 6. Chemical analysis of muscle tissues.


The measurement of "available lysine" in protein foods. A comparison of chemical, biological and microbiological methods.


Selection of stroke patients for arterial reconstructive surgery.


Combined pancreaticoduodenal trauma.

Combined pancreaticoduodenal trauma.


Incidence of elevated serum amylase levels and pancreatitis after upper abdominal surgery.


Chronic alcoholic pancreatitis. Treatment by ductal obstruction.


Correlation between clinical aspects and location of lesion in carcinoma of the head of the pancreas.


Resuscitation with hypertonic lactate saline in thermal injury.


Studies in the management of the contaminated wound. IX. Quantitation of the Evans blue dye content of open and primarily closed surgical wounds.


The open door in the operating room.

The open door in the operating room.


Surgical treatment of regional enteritis.


Perforation of the colon associated with adynamic ileus.


Survey of cecal and ascending colon injuries among Vietnam casualties in Japan (1967-1970).


Use of silastic tube and capillary sampling technic in the measurement of tissue PO 2  and PCO 2 .


Massive pulmonary embolism.

Massive pulmonary embolism.


Primary carcinoma of the male breast.

Primary carcinoma of the male breast.


Congenital familial anorectal anomaly.

Congenital familial anorectal anomaly.


Discontinuance of respiratory assistance after pulmonary insufficiency. Indications and results.


Late onset small bowel fistula due to tantalum mesh.


Self-inflating parachute cuff. A new tracheostomy and endotracheal cuff.


Embedding human skull bones in perspex blocks.


Surgical jaundice. Aspects of pathogenesis and diagnosis.


Effects of patulin and method of application on growth stages of wheat. When a single, 100-mug/ml application of patulin, produced by Penicillium urticae Bainier, was applied to growth stages 7, 9, 10, and 10.1 (Feekes scale) of Lee spring wheat (Triticum aestivum L.), decreases in internodal elongation, floret number, seed weight, and seed number were observed. Yields were reduced according to the proximity of application prior to heading. Application of patulin to the soil in crystalline form and dissolved in aqueous solution were also investigated, and the solution method of application was found to be the treatment of choice. A single exposure of growing wheat plants to patulin can produce yield reductions similar to those observed in stubble-mulch farming.


Microbial phospholipid synthesis as a marker for microbial protein synthesis in the rumen. Phosphate uptake into intracellular inorganic phosphorus and cellular phospholipids and the relationship between cell growth and phospholipid synthesis were studied with suspensions of washed ruminal bacteria in vitro with (33)P-phosphorus. It was shown that ruminal bacteria accumulated inorganic phosphate at a low rate when incubated without substrate. Upon the addition of substrate, the rate of inorganic phosphorus uptake into the cells increased markedly, and phospholipid synthesis and cell growth commenced. There was a highly significant relationship (r = 0.98; P < 0.01) between phospholipid synthesis and cell growth. The specific activity of the intracellular inorganic phosphorus did not equilibrate with phosphorus medium. When ruminal contents from sheep fed a high or low protein diet were incubated in vitro, the rate of (33)P incorporation into microbial phospholipids was higher for the high protein diet. Since there was a high relationship between phospholipid synthesis and growth, rumen contents were collected before and various times after feeding and incubated with (33)P-phosphorus in vitro. The short-term, zero time approach was used to measure the rate of microbial phospholipid synthesis in whole rumen contents. In these studies the average specific activity of the intracellular inorganic phosphorus was used to represent the precursor pool specific activity. Microbial phospholipid synthesis was then related to protein (N x 6.25) synthesis with appropriate nitrogen-to-phospholipid phosphorus ratios. Daily true protein synthesis in a 4-liter rumen was 185 g. This represents a rate of 22 g of protein synthesized per 100 g of organic matter digested. These data were also corrected for ruminal turnover. On this basis the rate of true protein synthesis in a 4-liter rumen was 16.1 g of protein per 100 g of organic matter digested. This value represents a 30-g digestible protein-to-Mcal digestible energy ratio which is adequate for growing calves and lambs.


Octene epoxidation by a cold-stable alkane-oxidizing isolate of Pseudomonas oleovorans. The isolation of an alkane-oxidizing strain of Pseudomonas oleovorans which maintains its viability at 5 C is described. This strain epoxidates 1-octene at a rate five times that of the parent strain. The most efficient substrates for induction of the epoxidase are C(7), C(8), and C(9), although C(5) to C(12) also serve as growth substrates and inducers. The greater rate may be attributed to an enhanced general stability of the cells as opposed to a modification of the enzyme system involved.


Some properties of acid protease from the thermophilic fungus, Penicillium duponti K1014. A purified acid protease from a true thermophilic fungus, Penicillium duponti K1014, was most active at pH 2.5 for milk casein and at pH 3.0 for hemoglobin. The enzyme was stable at a pH range of 2.5 to 6.0 at 30 C for 20 h. The acid protease retained full activity after 1 h at 60 C at a pH range between 3.5 and 5.5. At the most stable pH of 4.5, more than 65% of its activity remained after heat treatment for 1 h at 70 C. These thermal properties show the enzyme as a thermophilic protein. The enzyme activity was strongly inhibited by sodium lauryl sulfate and oxidizing reagents such as potassium permanganate and N-bromosuccinimide. No inhibition was caused by chelating reagents, potato inhibitor, and those reagents which convert sulfhydryl groups to mercaptides. Reducing reagents showed an activating effect. The enzyme showed the trypsinogen-activating property at an acidic pH range; optimal trypsinogen activation was obtained at a pH of approximately 3.0. The isoelectric point of the enzyme was estimated to be pH 3.89 by disk electrofocusing. By using gel filtration, an approximate value of 41,000 was estimated for the molecular weight.


Production and purification of acid protease from the thermophilic fungus, Penicillium duponti K1014. A thermophilic fungus, Penicillium duponti K1014, produced an acid protease in a submerged culture. Maximum enzyme production, in a 30-liter fermentor at a preselected optimum growth temperature of 50 C, occurred after 3 days. The productivity of the enzyme was associated with changes of viscosity and pH of culture broth during the growth. The acid protease was isolated from the culture filtrates and was purified ninefold by alcohol precipitation, column chromatography on O-(diethylaminoethyl)cellulose, batchwise treatment with O-(carboxymethyl)cellulose, and by gel filtration. The purified enzyme was homogeneous on disk electrophoresis and sedimentation analysis. The sedimentation constant s(20.w), calculated at a concentration of 0.64%, was 3.98S.


Production of D-alanine by Corynebacterium fascians. A strain identified as Corynebacterium fascians was found to accumulate extracellular D-alanine from glycerol. Cultural conditions for the accumulation of D-alanine were investigated and, as a result, a yield of 7 g of D-alanine per liter was obtained after a 96-h incubation in a medium containing 5% glycerol, 4% (NH(4))(2)HPO(4), and 0.3% corn steep liquor. Optical purity of D-alanine was dependent upon the concentration of corn steep liquor. At the optimal condition, almost optically pure D-alanine was formed and readily isolated (5 g/liter) from the fermentation broth. The product was not contaminated with any detectable amount of other amino acids, except for glycine which was present at a concentration of less than 1 percent.


Microbial hydroxylation of 5-anilino-1,2,3,4-thiatriazole. Two hundred eighty-five fungi, including 100 basidiomycetes and 35 yeasts, 75 actinomycetes, and 40 bacteria were screened for their ability to convert 5-anilino-1,2,3,4-thiatriazole (AT) to 5-(p-hydroxyanilino)-1,2,3,4-thiatriazole (p-HT). Eleven cultures were found that formed p-HT, which was isolated and whose structure was determined. Aspergillus tamarii NRRL 3280 formed 8.6 g of p-HT/liter from 10 g of AT/liter (78.9% conversion) in shaken flasks and 4.57 g of p-HT/liter from 6 g of AT/liter (69.8% conversion) in 30-liter fermentors. Washed cells of A. tamarii NRRL 3280 also carried out this conversion. 5-(o-hydroxyanilino)-1,2,3,4-thiatriazole (o-HT) was identified as a second product formed by Aspergillus terreus NRRL 1960.


Preparation of metabolites of spironolactone by microbial oxygenation. It has been postulated that 3-(3-oxo-7alpha-methylthio-4-androsten-17alpha-yl)propionic acid gamma-lactone (I) is a key intermediate in the metabolism of the anti-aldosterone agent, spironolactone (3-[3-oxo-7alpha-acetylthio-17beta-hydroxy-4-androsten-17alpha-yl] propionic acid gamma-lactone). In the present study it was found that microbial oxygenation of I by Chaetomium cochloides QM 624 gave three metabolites which retained sulfur in their molecules and were found to be identical to the human metabolites of spironolactone.


Production of  -endotoxin by Bacillus thuringiensis as a function of glucose concentrations. The insect pathogen Bacillus thuringiensis was cultured at different glucose concentrations. Size, protein content, and insecticidal activity of the parasporal inclusions, which are formed during the sporulation process, were measured. Increased glucose concentrations led to bigger crystalline inclusions with a higher content of protein and insecticidal activity. Maximum yields of protein and endotoxin were obtained in a semisynthetic medium that contained glucose concentrations of 6 to 8 g/liter.


Biological and chemical detection of trichothecene mycotoxins of Fusarium species. The procedure for biological and chemical detection of trichothecene-type mycotoxins and its application to the screening of Fusarium for toxic strains were described.


Distribution of steroid 1-dehydrogenation and side-chain degradation enzymes in the spores of Fusarium solani: causes of metabolic lag and carbohydrate independence. The spores of a strain of Fusarium solani 1-dehydrogenate ring A and cleave the 17beta-acetyl side chain of 17alpha-hydroxypregn-4-ene-3,20-dione (17alpha-hydroxyprogesterone) to give 17alpha-hydroxypregna-1,4-diene-3,20-dione (the 1-dehydro analogue) and little androsta-1,4-diene-3,4-diene-3,17-dione (androstadienedione). A 4-h lag period is observed in the course of metabolism, and there are no requirements for external additives. Exoenzymes or surface enzymes bound to the cell outside the plasma membrane, either in the periplasmic space or bound to the cell wall, cannot be detected. The spore activity is not destroyed by treatment with aqueous HCl (pH 1.50), indicating that the 1-dehydrogenation and side-chain degradation enzymes are located away from the surface of the spores. Phenethyl alcohol destroys the spore permeability barriers, and it is also likely that it exposes its enzymes to acid inactivation. The action of phenethyl alcohol is reversible at low concentrations and irreversible at high concentrations. This investigation shows that: (i) the spore 1-dehydrogenating and side-chain-degrading enzymes appear to be bound to, or imbedded in, the plasma membrane; (ii) the lag period observed in the course of metabolism of the steroid by the spores might be required for enzyme activation or diffusion of the substrate through the cell wall; and (iii) the internal metabolities of the spores, that might be required for the conversion process, appear to be present in a nondiffusible form or bound to intrasporal macromolecules.


Structural properties of acetylcholinesterase from eel electric tissue and bovine erythrocyte membranes.


The  -chymotrypsin-catalyzed hydrolysis of N-acetyl-L-tryptophan p-nitrophenyl ester in dimethyl sulfoxide at subzero temperatures.


Mechanism of warfarin resistance. Warfarin and the metabolism of vitamin K 1 .


Inactive enzyme molecules in aging organisms. Nematode fructose-1,6-diphosphate aldolase.


Helix-coil transition in nucleoprotein-chromatin structure.


Actinomycin D-mononucleotide interactions as studied by proton magnetic resonance.


Crystal structure of an antiviral agent 5-(N-(L-phenylalanyl)amino) uridine.


Isolation of a protein containing tightly bound 5-methoxybenzimidazolylcobamide (factor 3m) from Clostridium thermoaceticum.


Preparation, assay, and partial characterization of a neutral endopeptidase from rabbit brain.


Ribonuclease from human granulocytes.

Ribonuclease from human granulocytes.


Guinea pig brain acetylcholinesterase: partial purification by affinity chromatography.


A second form of arylsulfatase A in human urine.


Preparation and some properties of human pancreatic amylase including a comparison with human parotid amylase.


Effects of  -irradiation on the enzymatic properties of lysozyme.


Subsite affinities of glucoamylase: examination of the validity of the subsite theory.


Neutral hetero- -galactosidase from rabbit small intestine.


Beta-L-arabinosidase from Cajanus indicus: a new enzyme.


Synthesis and cleavage of L-lactylpuromycin and other lactyl derivatives by leucine aminopeptidase.


Rate enhancement of pyruvate aldolization by divalent cations: a model for class II aldolases.


Competitive inhibition of pancreatic elastase.


Synthesis of p-coumaroyl coenzyme a with a partially purified p-coumarate:CoA ligase from cell suspension cultures of soybean (Glycine max).


The physiological response of the estuarine clam, Rangia cuneata (Gray), to salinity. II. Uptake of glycine.


Regeneration in the African lungfish, Protopterus. 3. Regeneration during fasting and estivation.


Muscular activity underlying ventilation and swimming in the horseshoe crab, Limulus polyphemus (Linnaeus).


Bio-medical engineering at the University of Utah.


Reactions to Althesin.

Reactions to Althesin.


Metabolic changes after injury.

Metabolic changes after injury.


Blocked or non-functioning cannulae.

Blocked or non-functioning cannulae.


Compatibility of drugs with blood.

Compatibility of drugs with blood.


Clutton-Brock J,+CLUTTONAABROCK J:Static electricity and rotameters.


Nurse practitioners in primary care. 3. The southern Ontario randomized trial. A group of nurses who formerly had performed office functions received a special university-based educational program designed to prepare them to assume much of primary care management as nurse practitioners. The associated family physicians would shift their role to general supervision and attention to difficult clinical problems. To test this new form of practice, two complementary randomized trials have been conducted in south-central Ontario. The particular trial reported here was intended to assess the influence of the educational program on the changing roles of the professional personnel. The nurses of 14 family medical practices, with the physicians' support and commitment to participation, applied for the new training. Seven applicants were randomly selected to receive the training and their corresponding practices became the experimental group, while the remaining nurses and practices were retained as controls. During the subsequent year of investigation important changes occurred in professional roles of the experimental group. Nurse practitioners spent more time in clinical activities than conventional office nurses. The shift was not at the expense of time devoted to clinical work by physicians. Doctors delegated more professional activities to nurse practitioners than to conventional nurses. Except for remuneration (affected by legal constraints) job satisfaction among experimental physicians and nurses remained high after one year of experience with the new method.


Retroperitoneal fibrosis associated with Riedel's struma. A case of retroperitoneal fibrosis with bilateral ureteral obstruction in association with Riedel's struma of the thyroid is reported. There has been a definite increase in incidence of retroperitoneal fibrosis, but with prompt recognition and adequate treatment the mortality rate has been decreased from the original 14%. The association of Riedel's struma with retroperitoneal fibrosis has been noted in the past and its association with sclerosing cholangitis has also been mentioned. It is not known whether Riedel's thyroiditis originates in the thyroid gland and spreads or whether true thyroiditis is part of a generalized process. The temporal relationship of thyroiditis and retroperitoneal fibrosis suggests an extension of fibrosis from the thyroid, but one cannot be sure which condition occurred first. Whatever the cause, the treatment remains the same as for retroperitoneal fibrosis from other causes.


Designating your principal residence.

Designating your principal residence.


Retroperitoneal fibrosis in three siblings with the sickle cell trait. Three West-Indian black siblings with the sickle cell trait developed retroperitoneal fibrosis, a previously unreported association. Other well known renal manifestations associated with the sickle cell trait were also present in some of these cases and included renal medullary necrosis and spontaneous hematuria. It is postulated that the sickling of the erythrocytes in the periureteral vessels resulted in thrombosis, ischemia, reactive scarring and progressive fibrosis indistinguishable from the known histological picture of retroperitoneal fibrosis. The finding of fibrin thrombi in the small veins of the fibrotic tissue of one of these patients would support this explanation.


The nurse practitioner--to be or not to be?


Varicella and congenital defects.

Varicella and congenital defects.


Bioavailability.

Bioavailability.


Retroperitoneal fibrosis.

Retroperitoneal fibrosis.


The future of the local health department in Canada.


PKU screening.

PKU screening.


Nurse practitioners in primary care. I. The McMaster University educational program. In 1971 McMaster University offered an educational program for nurse practitioners sponsored jointly by the Faculty of Medicine and the School of Nursing. Priority in the pilot program was given to nurses employed in family practice settings and to those participating in related McMaster studies. Because of the implications of a change in role for both nurse and physician, one requirement for acceptance of a nurse in the program was participation of the physician-associate in the educational program.The program prepares registered nurses to extend their responsibilities in primary health care activities for the assessment and management of patients in family practice. The current evaluations of the pilot-study results suggest that such programs can contribute effective resources towards meeting expectations of ready access to primary care by the people of Canada.


Nurse practitioners in primary care. II. Prior attitudes of a rural population. A household survey in a medically underserviced rural population of south-central Ontario was conducted in early 1971 to ascertain attitudes about nurses as providers of primary care. The population sampled had not been exposed to nurse practitioners or family practice nurses before the survey was concluded. The results demonstrate favourable views about nurses giving services in health maintenance and sickness surveillance situations. Personal primary care rendered in homes was highly acceptable to respondents. Physician services were preferred in worry-inducing situations.


Energetics of muscular contraction.

Energetics of muscular contraction.


Thermal and biochemical changes in normal and diseased human muscle.


Energy metabolism in human muscle.

Energy metabolism in human muscle.


Studies on the physiology of skeletal muscle regenerates.


Morphological studies on transplanted muscle between normal and dystrophic animals.


The functional morphology of regenerating and transplanted mammalian muscles.


Isolation of human parathyroid hormone and determination of the amino-acid sequence of the amino-terminal part of the molecule.


A comparison of the control of intracellular pH in cardiac and skeletal muscle.


Factors affecting the viability of heart muscle exposed to anoxia and subsequent reoxygenation.


Effect of posture on bronchial dimensions in the dog.


A method for estimating pulmonary capillary blood flow from the rate of change of alveolar CO 2  pressure during rebreathing.


Action of levodopa on the blood pressure of conscious rabbits.


The role of central and peripheral mechanisms in the maintenance of experimental hypertension in the rabbit.


Glyceride-fatty acid and free fatty acid uptake by human adipose tissue in obesity.


Factors promoting intestinal hyperplasia in lactating rats.


Experimental expansion of the bile acid pool.


Effect of drugs which cause megaloblastosis on the free intracellular pools of DNA precursors.


The effect of dietary fat on platelet function.


Comparative release of enterokinase and other small intestinal enzymes following secretin and pancreozymin in man.


The effect of lead on   and   chain synthesis in vitro and in vivo.


Potentiation of platelet aggregation and adhesion by heparin both in vivo and in vitro.


The direct interconversion of glucose and fructose in human skeletal muscle with special reference to childhood muscular dystrophy.


Urinary Tamm-Horsfall glycoprotein in certain kidney diseases and its content in renal and bladder calculi.


The relationship of height and weight velocities of adolescent boys to the total hydroxyproline: creatinine ratio in their random urines.


Chloride titration in the dog: the influence of extracellular fluid expansion on the pattern of chloride reabsorption.


Renal control of changes in the compliance of the interstitial space: a factor in the aetiology of renoprival hypertension.


Plasma catecholamine and dopamine  -hydroxylase amounts in phaeochromocytoma.


The community adaptation schedule and the adjective check list: A validational study with psychiatric impatients and outpatients.


The mobile unit: a new approach in mental health.


Institutions and community mental health: the paradox in Wyatt V. Stickney.


Local participants in planning for comprehensive community mental health centers: The Colorado experience.


Problems and challenges for the mental health professional consulting to a community action organization.


Contextual approach to assessment.

Contextual approach to assessment.


Advanced training in community psychology: the role of training in community systems.


An educational program in mental health statistics.


Regional blocks for the relief from pain.


Treatment of pain due to malignancy in the head and neck.


Pain following peripheral nerve injuries.


Pain problems of significance in the head and face, some of which often are misdiagnosed.


Pain in the thoracic and abdominal viscera.


Endoscopic retrograde cholangiography. Experience of 168 examinations.


Gastric and duodenal ulceration associated with aspirin ingestion.


Correlation between gastroscopic and direct vision biopsy findings.


Lymphoreticular hyperplasia of the stomach (pseudolymphoma).


Psychological preparation for an endoscopic examination.


Clinical analysis of reflux esophagitis in symptomatic patients.


Gastric and esophageal telangiectasia: a case report.


Carcinoma of the esophagus developing in progressive systemic sclerosis.


Removal of an intragastric foreign body using the flexible fiberoptic esophagosscope.


European society of gastrointestinal endoscopy.


A "tip" on passing the 'scope'.

A "tip" on passing the 'scope'.


Fiberoptic stomoscopy.

Fiberoptic stomoscopy.


Endoscopic removal of an intragastric segment of retained nasogastric tube.


Endoscopic removal of a duodenal adenoma.


The effects of Methallibure (I.C.I. 33,828) and thiourea on gametogenesis in the firetail gudgeon, Hypseleotris galii.


Fine structure of the normal, transplanted and postmetamorphic pars distalis of the Mexican axolotl, Ambystoma mexicanum.


Hypothalamic-hypophysial relationships in the South American lungfish Lepidosiren paradoxa.


Variations in the in vitro production of corticosteroids by the herring gull (Larus argentatus) adrenal glands.


Secretion of 17-deoxycorticosteroids by herring gull (Larus argentatus) adrenals.


Histological observations on bone and cartilage of growing turtles treated with calcitonin.


Circadian variation in activity of the duck (Anas platyrhynchos) adrenal gland.


Adaptive variations in prolactin secretion in relation to external salinity in the teleost Poecilia latipinna.


Daily rhythms of plasma corticosterone in the common pigeon, Columba livia.


The biosynthesis of adrenal steroids by the 15-day-old chick embryo.


The role of the thyroid in testicular function in the gecko, Coleonyx variegatus.


Correlation of gamete shedding with presence of neurosecretory granules in asteroids (Echinodermata).


Incorporation of cysteine into the cerebral neurosecretory system of adult desert locusts.


The pituitary gland and calcium metabolism in Fundulus diaphanus (teleosteii).


Foccicle boundary cells in the adenohypophysis of the chondrostean and holostean fishes: an ultrastructural study of their relationship to the follicular lumen, to endocrine cells, and to the hypophysial cleft.


Glycolytic and lipolytic effects of ovine FSH and estradiol-17  in the lizard Anolis carolinensis.


Chromatographic separation of urotensins.


Transmigration and infiltration of leucocytes in human junctional epithelium.


Periodontal probing: interinvestigator discrepancies and correlations between probing force and recorded depth.


The influence of methyl groups on toxicity and drug metabolism.


Rapidity of penetration of radiolucent areas through mesial enamel of first permanent molars.


Implications of patients missing medication visits on a methadone program.


Uncontrolled study with pipothiazine palmitate.


Nicotinic acid and catechol-O-methyl-transferase activity in schizophrenia.


Effects of chronically administered   1 -tetrahydro-cannabinol on adrenal and gonadal activity of male rats.


Low dosage methadone maintenance: a re-examination.


Some remarks on the influence of lithium carbonate on patients with temporal epilepsy.


Simultaneous mesoridazine and psychodrama in neurotics.


Automatic determination of the pain threshold to electroshock and the effects of 9 -THC.


Simplified screening test for phenotyping of isoniazid inactivators.


Cephacetrile--a new cephalosporin antibiotic.


Rheumatoid arthritis of the foot.

Rheumatoid arthritis of the foot.


Calcaneal osteotomy for valgus and varus deformities of the foot. Further experience.


Square nailing and immediate use of the limb in forearm fractures.


Proteolytic enzymes for minimizing deformities associated with Colles' fracture.


Nonmetastatic abdominal presentation of bronchogenic carcinoma.


Intralobar pulmonary sequestration.

Intralobar pulmonary sequestration.


Female sterilization by culdoscopy.

Female sterilization by culdoscopy. This is a 1 year study on the use of a culdoscopic sterilization technique on 250 patients aged 25 or more with at least 4 children and at least 6 weeks Postpartum.  Clinical examination was made to exclude tumors, infections, or endometriosis.  The laparoscope was used for transvaginal female sterilization employing a culdoscopic technique.  Under direct vision the fallopian tube is brought to the vagina with the aid of long handled forceps.  The tube is crushed at a point and 2 transfixing linen, silk or nylon sutures are tied 3 mm. on either side of the crushed point.  The method is simple and effective.  Gaseous distention occurred in 12.0%, menstrual upsets in 4.4%, and vaginal discharge in 7.0%.  12 patients developed granulation tissue at the operation site.  Advantages include use of local anesthetic, no abdominal scars and discharge the following day.


Late recurrent gastric carcinoma.

Late recurrent gastric carcinoma.


Antro-oral fistula.

Antro-oral fistula.


5th Western Hemisphere Congress.

5th Western Hemisphere Congress.


The arthritic hip.

The arthritic hip.


Surgical lesions of the head of the pancreas in lithiasis.


The case report.

The case report.


Surgical therapy of renovascular hypertension in subjects with one kidney.


Genesis, diagnosis and treatment of vascular complications after intervertebral disk surgery.


Bioengineering analysis of sutureless wound closure.


Localization of the vulnerable period.

Localization of the vulnerable period.


Osteosynthesis with screwed plates in maxillofacial surgery. Experience with 500 satellite plates.


Desmoid tumor and laparotomy scars.

Desmoid tumor and laparotomy scars.


Deep femoral artery-saphenous vein shunt for hemodialysis.


Myelodysplasia and the neurogenic bladder in the Nigerian neonate.


Accidental rupture of the pregnant uterus.


Gastric syphilis. A note on a forgotten disease.


Dichotic speech perception: an interpretation of right-ear advantage and temporal offset effects.


Study of U.S. medical school applicants, 1971-72.


External fiscal controls on the teaching hospital: the Philadelphia experience.


Psychological problems associated with sleep deprivation in interns.


The effectiveness of simulation devices in teaching selected skills of physical diagnosis.


Programmed learning strategies in tropical parasitology.


A new trend in career interests among University of Michigan medical school graduates.


Use of the problem-oriented record by junior medical students in pediatric ambulatory care.


Book prices.

Book prices.


COTRANS: a progress report.

COTRANS: a progress report.


Role of pharmacology in physician education.


The teaching laboratories.

The teaching laboratories.


Fetal movements and Werdnig-Hoffmann disease.


Cerebral and pontine myelinolysis. Two cases with fluid and electrolyte imbalance and hypotension.


Chronic benign lymphocytic meningitis.

Chronic benign lymphocytic meningitis.


The distribution and frequency of spontaneous fasciculations in motor neurone disease.


Excess dietary methionine and pregnancy in the rat.


Changes occurring in the head of boar spermatozoa: vesiculation or vacuolation of the acrosome?


Evidence for the penetration of the vitelline membrane of the hen's ovum by a trypsin-like acrosomal enzyme.


Ovarian venous blood PO 2 , PCO 2  and pH in women.


The absence of any effect of maternal-fetal incompatibility at the H-2 and H-3 loci on pregnancy in the mouse.


Recovery of spermatogenesis in patients with lymphoma after treatment with chlorambucil.


Persisting structural alterations in the uterus and ovaries of rats induced by intrauterine devices.


Sexual dimorphism in the submaxillary gland of the pig.


Some aspects of the composition of buffalo semen.


Chemical sympathectomy of the rabbit oviduct using 6-hydroxydopamine.


Post-fertilization maternal effects on sperm dimensions of inbred mouse strains.


Reproductive efficiency in aged female rabbits given supplemental progesterone and oestradiol.


Electrophoresis of protein fractions from boar seminal plasma, vesicular secretion and epididymal plasma.


Steroid metabolism by the chin gland of the male cuis, Galea musteloides.


Effects of hysterectomy on corpus luteum activity in the cyclic, pseudopregnant and pregnant mouse.


Continuous measurement by radio-telemetry of vaginal pH during human coitus.


Effects of avian and mammalian pituitary preparations on induction of ovulation in the domestic fowl, Gallus domesticus.


Influence of water deprivation on adrenocortical rhythms.


Sex-dependent increase in pineal hydroxyindole-O-methyl transferase activity after a single intraventricular injection of 6-hydroxydopamine to newborn rats.


Role of hypothalamus on development of adenohypophysis: an electron microscopic study.


Treatment of chronic obstructive pulmonary disease.


Pituitary-adrenal activity and depletion of brain catecholamines after central administration of 6-hydroxydopamine.


Blockade of vasoconstriction by isoxsuprine (vasodilan) in the isolated perfused rabbit kidney.


Electrocardiographic changes induced by some phenothiazine derivatives.


Spectroscopic observations of synaptosomal membranes: the effect of morphine.


Free amino acids of plasma in the acute phase of experimental necrotic liver damage.


Influence of microcrystalline collagen in wound healing. II. Comparison of several collagen dressings on excised wounds of pigs and rabbits.


Depression of enzymic esterification of N-hydroxy-AAF in the liver during aminoazo dye carcinogenesis in the rat.


Species variations in binding of  63 NI(II) by serum albumin.


Rat kidney acid hydrolase and glycoprotein:glycosyltransferase activity in lead intoxication.


Inhibition of protein synthesis in rat liver by D-galactosamine.


Dose dependent inhibition of  59 Fe incorporation into erythrocytes after a single dose of benzene.


Steady state glucose dynamics in hyperthyroid rabbits.


Prostaglandins and synaptosomal transport of  3 H-norepinephrine and  3 H-5-hydroxytryptamine.


A neuroanatomical study of the brainstem auditory system of the rabbit. II. Descending connections.


The early developmental stages of the chondrocranium of Agama pallida.


Some hazards of aquatics.

Some hazards of aquatics.


Salicylate poisoning. Comparison of acetazolamide administration and alkaline diuresis in the treatment of experimental salicylate intoxication in puppies.


Phantom breathing in monitored infants.

Phantom breathing in monitored infants.


Hydrocephalus. A definition of its progression and relationship to intellectual function, diagnosis,  and complications.


Use of the nitroblue tetrazolium dye test. An aid in managing patients with cystic fibrosis.


Bubble formation in the roller infusion pump.


Radiological case of the month.

Radiological case of the month.


Brachmann-de Lange syndrome. Report of two cases in a sibship.


Endocardial fibroelastosis and aneurysmal dilatation of the left atrial appendage.


Cervical aortic arch.

Cervical aortic arch.


Thyroid acropachy.

Thyroid acropachy.


Systemic venous anomalies and partial heterotaxia with normal heart.


Hyperglycemic nonketotic coma in a postpancreatectomy diabetic infant.


Protein uptake by rat preimplantation stages.


An electron microscopic analysis of the nerve of the pterygoid canal in the mouse.


The ultrastructure of intradental nerves in developing mouse molars.


Preliminary studies on in vitro and in vivo effects of 50 per cent hypaque on coagulation in man.


The effect of sodium dextrothyroxine on serum cholesterol and mortality rates in cardiac patients.


Ebstein's anomaly of the tricuspid valve associated with persistent left superior vena cava draining into the left atrium.


Ventricular septal defect following nonpenetrating trauma. Case report and review of the surgical literature.


A phlebographic study of the soleal sinuses.


Characteristics of the dicrotic notch of the arterial pulse wave in coronary heart disease.


Seeing the world through a new sense: electroreception in fish.


Tryptophan to niacin pathway in scleroderma and in dermatomyositis.


Acantholysis through washing powder enzymes. The effect of proteolytic washing powder enzymes on surviving skin.


Basal system of the ethmoidal labyrinth in man. I.


Structural pattern of the ethmoidal labyrinth in adult man. II.


Vocal rehabilitation with a tracheo-esophageal shunt.


Radical neck dissection. Mortality and morbidity.


Simultaneous bilateral radical neck dissection. Preservation of the external jugular vein.


Thyroid gland in the management of laryngopharyngeal cancer.


Malignant melanoma of the nasal cavity and paranasal sinuses.


Plasmacytoma of paranasal sinuses and nasal cavity.


Familial carotid body tumors.

Familial carotid body tumors.


Cancer of the laryngopharynx and cervical esophagus. Radical resection with repair by colon transplant.


Surgical treatment of carcinoma of the pyriform sinus.


Simultaneous malignant tumors in patients with head and neck cancer.


The effects of a new coronary vasocilator (BAY-a-1040, Nifedipine) on the coronary and systemic haemodynamics in the anaesthetized dog.


Nasopharyngeal reflexes: integrative analysis of evoked respiratory and cardiovascular effects.


A systems approach to baroreceptor reflex control of the circulation.


Central nervous resetting of baroreceptor reflexes.


Components in the regulation of salt balance: salt appetite studied by operant behaviour.


Energy charge control of the Calvin cycle enzyme 3-phosphoglyceric acid kinase.


Self-induced crosslinking of factor XIII.


Solubilization from skeletal muscle of two components that specifically bind  -bungarotoxin.


Incorporation of eel electroplax acetylcholinesterase into black lipid membranes. A possible model for the cholinergic receptor.


The absence of saturated pyrimidine bases in chromatin-associated RNA from avian reticulocytes and mouse ascites cells.


Studies towards the complete sequence determination of proteins by mass spectrometry: derivatisation of methionine, cysteine and arginine containing peptides.


Side reactions of hydrogen fluoride on peptides containing glutamic acid in or near the C-terminus in solid phase synthesis.


Thermodynamical analysis of oxygen equilibrium of stripped hemoglobin.


Evidence for detection of AT 32 P bound at the coupling sites of mitochondrial oxidative phosphorylation.


Effect of chloramphenicol and cycloheximide on the synthesis of nitrate reductase and nitrite reductase in rice leaves.


The effect of indomethacin on the response of thyroid tissue to thyrotropin.


Nuclear and cytoplasmic receptors for 1,25-dihydroxycholecalciferol in intestinal mucosa.


Electrophoretically homogeneous myeloma light chain mRNA and its translation in vitro.


A protein related to immunoglobulin light chain detected in mouse myeloma cells.


Selectivity in aqueous peptide synthesis by  1 -ethyl- 3-(3- Dimethylaminopropyl) carbodiimide. A model for primordial processes.


An evaluation of gradient acrylamide gel electrophoresis and acrylamide gelisoelectric focusing for the primary separation of complex mixtures of proteins: comparison of one- and two-dimensional analytical procedures.


Use of serum albumin microspheres as a reversible adsorbent for studying protein-small molecule interactions.


Comparison of the oxygen and proton binding behavior of human hemoglobin A and A 2 .


Protein binding of small molecules. II. Role of electrostatic forces for binding of phenol red by human serum albumin.


Two new hemoglobin variants with deletion. Hemoglobin tours: Thr   8 7  (F 3 ) deleted and hemoglobin St Antoine: Gly-Leu   74-75 (E 18-19 deleted. Consequences for oxygen affinity and protein stability.


Physical chemical properties of chick cartilage collagen.


Circular dichrosim of visual pigment analogues containing  3 -dehydroretinal and 5,6-epoxy-3-dehydroretinal as the chromophore.


Simple procedures for the separation and identification of bovine milk whey proteins.


Receptor hydrophobic protein fraction from intestinal smooth muscle binding muscatinic ligands.


Phosphorylation of rabbit reticulocyte ribosomal proteins in vitro.


Insulin degradation. IV. Sequential degradation of insulin by rat kidney, heart and skeletal muscle homogenates.


Osmoregulation of ribosomal function in mouse liver.


DNA polymerase from mitochondria of rat intestinal mucosa.


Polyribosomes from maize leaves. Isolation at high pH and amino acid incorporation.


Control of globin synthesis by hemin. Effect of temperature on globin synthesis by the reticulocyte cell-free system and the activity of translational repressors formed in the absence of hemin.


Physical bases for mental illnesses.

Physical bases for mental illnesses.


Diagnosis of thyrotoxicosis.

Diagnosis of thyrotoxicosis.


Management of coeliac disease.

Management of coeliac disease.


Profits from drugs.

Profits from drugs.


Full strength to extra mild.

Full strength to extra mild.


Gallstone composition.

Gallstone composition.


Lithium and pregnancy. II. Hazards to women given lithium during pregnancy and delivery. The renal lithium clearance of a manic-depressive woman rose when she became pregnant and fell to the prepregnancy level when she gave birth. The lithium clearances of four healthy women were higher during pregnancy than after delivery. This emphasizes the need for frequent determinations of the serum lithium concentration and appropriate dosage adjustments during pregnancy and delivery.


Lithium and pregnancy. 3. Lithium ingestion by children breast-fed by women on lithium treatment. Children breast-fed by women on lithium treatment ingested lithium with the milk. Their serum lithium concentration was one-third to one-half the concentration in the nursing women's serum. Bottle-feeding should be considered for children of women on lithium treatment.


Relation of abnormal cytological smears and carcinoma of cervix uteri to husband's occupation. An analysis of the cytological records of almost 300,000 women in the Manchester area shows that the rates of positive/suspicious findings from population screening are highly correlated with the rates of mortality from cancer of the cervix when both are distributed according to the occupation of the husband. The correlation holds for various occupational groupings and for all the individual occupation units in which there are more than 1,000 women. This evidence strengthens the case for believing that the condition revealed by a positive smear is a stage in the development of invasive cancer of the uterine cervix.


Gastric acid secretion and diagnosis of Zollinger-Ellison syndrome. One hundred and fifty patients suspected of having Zollinger-Ellison syndrome were investigated. High plasma gastrin levels were found in 23 and in 16 a diagnosis of Zollinger-Ellison syndrome was confirmed. Measurement of the basal and maximal acid outputs showed that these simpler investigations have considerable value as screening tests for the selection of those patients in whom gastrin studies are indicated.


Induction of labour in sheep and in humans by single doses of corticosteroids. In sheep the administration of single intramuscular injections of dexamethasone into the fetus was shown to be an effective method of initiating parturition. In a controlled trial in women who had gone beyond the 41st week of pregnancy 20 mg betamethasone in saline (six patients) or saline alone (five patients) was injected into the amniotic fluid. In the betamethasone-treated group delivery occurred 78.9 +/- 10.2 (S.D.) hours after injection while in the control group it occurred 323 +/- 62 (S.D.) hours after injection (P < 0.01). In one woman with an anencephalic pregnancy intra-amniotic injection failed to initiate parturition but delivery occurred 88.5 hours after intramuscular injection of betamethasone into the fetus.


Strongyloidiasis of respiratory tract presenting as "asthma".


A case of hydrocolpos.

A case of hydrocolpos.


Anaesthetic contamination.

Anaesthetic contamination.


Malaria risk to travellers.

Malaria risk to travellers.


Fibreoptic endoscopy and the barium meal--results and implications.


Bone marrow in infectious mononucleosis.


Strychnine-containing tonics.

Strychnine-containing tonics.


Camphor poisoning in children.

Camphor poisoning in children.


Biological availability of digoxin.

Biological availability of digoxin.


Grades of hypothyroidism.

Grades of hypothyroidism.


Intestinal motility and absorption.

Intestinal motility and absorption.


Postoperative empyema and survival in lung cancer.


Cubital tunnel external compression syndrome.


Injury on the football field.

Injury on the football field.


Bacteroides infections.

Bacteroides infections.


Poultry diseases diagnosed in Canadian laboratories for the year 1971.


Gastrointestinal parasites in cattle in Ontario.


Granular stomatitis in dogs due to Burdock.


Complications of ovariohysterectomies.

Complications of ovariohysterectomies.


Studies in the ganglioside series. VII. Total synthesis of Tay-Sachs' globoside.


Carbon-13 and proton nuclear magnetic resonance of unsonicated model and mitochondrial membranes.


A specific assay for plasma oxalate.

A specific assay for plasma oxalate.


Use of confidence intervals to assess precision of normal range estimates.


Use of data from patients in assessing interlaboratory proficiency and for quality control.


An automated method for the determination of estrogens in pregnancy urine.


Automated determination of serum cystine aminopeptidase.


The molecular structure of human ceruloplasmin: a proposed model.


The fluorometric determination of uric acid by use of the uricase-peroxidase system and 3,5-diacetyl-1,4-dihydrolutidine as secondary substrate.


Nephelometric determination of pancreatic enzymes. II. Lipase.


A simple and rapid method for the determination of 4-hydroxy-3-methoxymandelic acid (HMMA) in urine.


An improved amylase assay using dyed amylopectin.


Identification and quantitative determination of urinary bile acids excreted in cholestasis.


Effects of oral contraceptives and obesity on carrier tests for phenylketonuria.


Clinical chemistry of 3-methoxy-17-epioestriol (epimestrol).


Creatine phosphokinase level in neuromuscular disorders. Effect of dilution and dialysis.


Hb-Genova (  2   2 28(B10)Leu leads to Pro ); methods for detection and analysis of unstable hemoglobins.


A kinetic method for the estimation of pseudocholine esterase using naphthyl acetate substrate.


The determination of copper and zinc in biological materials. A comparison of atomic absorption with spectrophotometry and neutron activation.


A semi-automated reaction rate analysis for D- -hydroxybutyrate in blood.


Comparison of dipeptide arylamidase I and II. Amino acid arylamidase and acid phosphatase activities in normal and pathological human sera.


Loss of catecholamine derivatives during gas-liquid chromatography.


Interference from citrate using Mann's dye method for magnesium determination.


Non-operative removal of residual common duct stones.


Ischemic gastroenterocolitis in infants: clinical aspects and thoughts on its etiology.


Approach to pancreatic trauma.

Approach to pancreatic trauma.


The myth of legal liability.

The myth of legal liability.


Locating the city Health Director at the hospital.


Informed consent.

Informed consent.


What the clinician needs to know about radiology.


What the clinician needs to know about electrocardiography.


Diet and coronary heart disease.

Diet and coronary heart disease.


Queuing and rosette molting in Automeris io (Lepidoptera: Saturniidae).


Androgens in skin surface lipids.

Androgens in skin surface lipids.


17- -Hydroxy-steroid-dehydrogenases in hair follicles of normal and bald scalp: a histochemical study.


Sebaceous gland secretion in Parkinson's disease during L-dopa treatment.


Inhibition of Staphylococcus aureus lipase by tetracycline.


Properties of RNA polymerases from B16 melanoma.


Wegener's Granulomatosis.

Wegener's Granulomatosis.


Contracting cecal lesion.

Contracting cecal lesion.


Prophylactic clipping of the inferior vena cava.


Characteristics of vasectomy patients utilizing a mobile unit in Georgia.


Summary of medical legislation 1973 Georgia General Assembly.


The clinical importance of the trifascicular conduction concept.


Medical records: an attorney's view.

Medical records: an attorney's view.


Ethyl palmitate-induced bartonellosis as an index of functional splenic ablation.


Reticuloendothelial system function. VI. Experimental alterations influencing the correlation between portal blood flow and colloid clearance.


Diagnosis of adrenal hypertension. I. Selective adrenal venography and pharmacological evaluation using catheter technique for detecting pheochromocytoma.


Development of humoral and cellular aspects of macrophage function in fostered and nonfostered neonates.


Nephralgia due to an aberrant renal capsular vessel: case report.


The use of intraoperative renal arteriography in evaluating renal injuries.


Injuries associated with renal trauma.

Injuries associated with renal trauma.


Traumatic renal artery thrombosis.

Traumatic renal artery thrombosis.


Extended pyelolithotomy (Gil Vernet's pyelotomy).


A malleable nephrostomy sound and a technique for its use.


Renal carbuncle: antibiotic therapy governed by ultrasonically guided aspiration.


Renogastric fistula: case report and review of the literature.


Spontaneous rupture of the kidney: a complication of anticoagulation--report of 2 cases.


The pathophysiology of primary megaloureter.


Ureteral avulsion from blunt trauma.

Ureteral avulsion from blunt trauma.


Transureteroureterostomy: a neglected procedure.


An intestinal valve in urinary diversion.


A new flexible fibercystoscope for visualization of the bladder neck.


Youssef's syndrome: a case report.

Youssef's syndrome: a case report.


Study and diagnosis of bladder tumors by triple contrast cystography.


Silicone granuloma of the penis.

Silicone granuloma of the penis.


Urethral extrusion of a penile prosthesis associated with urethritis.


Spongiosograms and cavernosograms: a study of their value in priapism.


Plasma gonadotropins in germinal cell aplasia (Sertoli-cell-only syndrome).


Adenocarcinoma of the rete testis: report of a case.


Estrogen dosage and suppression of testosterone levels in patients with prostatic carcinoma.


Transpubic radical prostatectomy: report of a case.


A new office test for bacteriuria.

A new office test for bacteriuria.


Hereditary xanthinuria and xanthine urolithiasis: an additional 3 cases.


Critical evaluation of uroflowmeters and analysis of normal curves.


A new apparatus for cystoscopic photography with interchangeable lens groups: available for endocinematography and endotelevisionoscopy.


Malignant hyperthermia: a catastrophic complication.


Vesicoureteral reflux in children: a computerized review.


A technique for preconditioning the peristomal skin for ileal loop urinary diversion.


Megalourethra.

Megalourethra.


Surgical correction of male epispadias with total incontinence.


Psychological aspects of vasectomy. 1. Helping the patient decide. In early 1972 a form of consent for vasectomy was approved by New South Wales Medical Defense Union which calls the patient's attention to the possibility of a change in his sexual life but points out the psychological effect of the procedure  is under the command of the patient.  Vasectomies have increased considerably since the possibility of this occurrence has been brought out.  Physicians are more aware of the two types seeking vasectomies, normally adjusted persons and a much smaller group who may have neurotic motives.  They must be prepared to answer all questions pertaining to vasectomy and recognize those patients with neurotic intentions, in order to assure themselves of the foresight to ask for a psychiatric exploration of the patient before performing  the vasectomy.  The major objection to a vasectomy is permanence.  In the United States sperm banks have been set up and have functioned effectively as a deposit method for prevasectomy patients.  99% of the depositors never call upon their specimen.


Purulent meningitis and sensitivity tests.


Malignant hyperpyrexia.

Malignant hyperpyrexia.


Transport across the intestine.

Transport across the intestine.


Malignant hyperpyrexia in Australia and New Zealand.


Study of casualty patients at an urban hospital.


Total avulsion of the scalp.

Total avulsion of the scalp.


Mountain sickness in the Australian alps.


Microbiopsy of the urinary bladder--a method involving minimal traumatization.


Saving the amputated digit and hand.

Saving the amputated digit and hand.


Pregnancy at 40 years and over.

Pregnancy at 40 years and over.


Hexachlorobenzene pesticides and porphyria.


Asymptomatic gonorrhoea in women: a prevalence survey in Sydney.


Standards and the Australian Medical Association.


Platelet survival and adhesiveness in recurrent venous thrombosis.


The BMA and the organization of medicine.


Effects of "free" medical care on medical practice--the Quebec experience.


Ambulatory-care data.

Ambulatory-care data.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-1973.


Emergency treatment of angiography-induced paraplegia and tetraplegia.


Thymoma and red-cell aplasia.

Thymoma and red-cell aplasia.


Smoking and coronary heart disease.

Smoking and coronary heart disease.


Dollar costs of nonsupport of research.

Dollar costs of nonsupport of research.


Certificate-of-need laws.

Certificate-of-need laws.


The vanishing training grant.

The vanishing training grant.


Action of black widow spider venom on an aminergic synapse.


Elevated ozone levels in the air of Central London.


Maintenance of lactational diestrum in the postpartum rat through tactile stimulation in the absence of suckling.


Electrodermal activity as an index of arousal in schizophrenics.


Moral conduct and moral character: a psychological perspective.


Socioeconomic status and traditional treatment approaches reconsidered.


The effects of oxygen on intestinal crypt survival in cobalt-60-irradiated mice.


The biophysical properties of 3.9-GeV nitrogen ions. II. Microdosimetry.


Effects of metabolic inhibitors on giant cell formation in Oedogonium cardiacum.


Lethal damage after x- and uv-irradiation and its modification by hypoxia and cycloheximide.


Effects of chronic environmental radiation on a natural population of the aquatic snail Physa heterostropha.


Radiation-induced change in serum and urinary amylase levels in man.


Review and evaluation of molecular weight calculations from the sedimentation profiles of irradiated DNA.


Dosimetric properties of neutron beams produced by 16-60 MeV deuterons on beryllium.


Enzymatic changes in beta-irradiated epidermis of guinea pigs: extracellular and intracellular deoxyribonuclease I--A correction.


Egg production in hens continuously irradiated as embryos.


Reactions in micellar systems.

Reactions in micellar systems.


Gangrenous large bowel proximal to gangrenous sigmoid volvulus.


The use of plaster of Paris to fill large defects in bone. An experimental study to determine the ultimate fate of a measured amount of plaster of Paris inserted into the bone of a living animal.


Congenital antral membrane.

Congenital antral membrane.


Ileosigmoid knot and sigmoid volvulus.

Ileosigmoid knot and sigmoid volvulus.


Diffuse eosinophilic gastro-enteritis with granuloma formation.


Florid post-inflammatory polyposis of the colon.


Thrombosis of the renal artery due to trauma.


Conn's syndrome.

Conn's syndrome.


Eosinophilic infiltration of the gastro-intestinal tract. (A review of the literature with three additional cases).


Pancreatic tumour in infants.

Pancreatic tumour in infants.


Bacterial endocarditis.

Bacterial endocarditis.


Septic abortion and septic shock.

Septic abortion and septic shock.


Treatment of advanced carcinoma of the larynx.


Obstruction of the left main coronary artery--the artery of sudden death.


The South African child in hospital.

The South African child in hospital.


Pectus excavatum: a modified technique of internal fixation.


Successful treatment of hepatic coma, complicated by renal failure, with exchange transfusion and peritoneal dialysis.


The hereditary nature of adult-onset heart block.


Parathyroid hormone concentrations in postgastrectomy patients.


Septal perforation after myocardial infarction.


Today's youth.

Today's youth.


Nutritional status survey of Pretoria schoolchildren from four racial groups.


Potentiation by previous drug therapy of hepatotoxicity following paracetamol overdosage.


The effect of vagotomy and drainage on the composition of bile.


Detection of carriers of classic haemophilia.


The inhibition of liver regeneration by the intraportal infusion of fresh serum after partial hepatectomy in the rat.


Recent changes in expected family size: some panel results from Rhode Island.


Population growth, contraception, and the high school student in the rural Punjab. To determine attitudes toward contraception, population growth, and the role of women, a questionnaire was administered to 317 high school students in India's rural Punjab during May 1969.  Average age for the sample group was 15, and it included 157 girls from 21 home villages and 160 boys from 22 in the Ludhiana District.  66% of the male population within the district were illiterate while 35% of the respondents ahd illiterate fathers.  Maternal illiteracy was 73% for the sample, 92% for the overall district (ages 35-59).  83% of the respondents felt their village population to be increasing, 89% knew India's population was growing.  13% of the sample cited concern that growth exacerbates the food shortage.  88% of the lower caste girls compared to 75% of the upper Jat caste girls were aware of local population growth.  The majority of the respondents favored small family size while boys were more likely to see the advantages of large family.  17% of the sample (22% of the boys, 13% of the girls) noted the availability of extra labor; 6% (11% of the boys, 1% of the girls) mentioned the military defense advantages of a large family.  Girls with less exposure tended to more progressive on population issues than those with more nontraditional backgrounds.  88% of 40 girls living more than 12 miles outside of Ludhiana City compared to 71% of 118 girls living nearer cited child educational benefits in a small family.  This tendency was reversed among the boys with 3% of 78 from townsize villages compared to 20% of 79 from smaller villages noting the labor advantages of a large family.  The total sample desired a mean of 2.71 children (girls 2.39, boys 3.04).  6.7% of the girls wanted 0 children compared to none of the boys.  Both sexes wanted more sons than daughters but the larger number of children desired by males reflects their desire for more sons and a lower estimation of females.  Girls from more traditional backgrounds displayed more contraceptive knowledge than the other females.  55% of those with fathers in nonmodern jobs compared to 31% of those whose fathers were teachers, businessmen or clerks, and 72% of 39 girls living more than 12 miles from Ludhiana City compared to 42% of 116 living nearer reported contraceptive knowledge.   This difference may be due to a modesty inculcated by the social milieu of girls from less traditional backgrounds.  83% of the girls and 34% of the boys knew of family planning from some form of government-sponsored propaganda.  These educated teenagers display a high awareness of population growth and a low reproductive goal in comparison to the older generation.  Development of a more positive evaluation of female capabilities than is traditional in rural Punjab migh reduce the strong male desire for sons and ideal family size would diminish accordingly.


Some species of Lecithaster Lühe, 1901 (Digenea: Hemiuridae) and related genera from fishes in the northern Gulf of Mexico.


A Colombian view of the condom.

A Colombian view of the condom.


Hatching and in vitro cultivation of the nematode Ascaridia galli to the third-stage larva.


Nematodes of Nevada ground squirrels, with description of two new species.


Studies on the host-specificity and development of the adult striged trematode Cotylurus flabelliformis.


Helminths from terrestrial molluscs in Nebraska. I. New host and locality records for Cosmocercoides dukae (Holl, 1928) Travassos, 1931 (Nematoda: Cosmocercidae).


Monogenetic trematodes from the bluespot sunfish Enneacanthus gloriosus (Holbrook) in North Carolina.


Some internal parasites of the California gull Larus californicus Lawrence, in Wyoming.


Eimeria banffensis n. sp. (Protozoa: Eimeriidae) from the pika Ochotona princeps from Alberta.


Redescription of Porrocaecum sulcatum (Rudolphi, 1819) from the sea turtle Chelone mydas.


A comparison of the effect of sodium diethyldithiocarbamate on the central nervous system of young and adult domestic fowl.


Intracranial mesenchymal chondrosarcoma.


Low-set ears.

Low-set ears.


Cerebral vascular accidents in cyanotic congenital heart disease.


Androgens and athletes.

Androgens and athletes.


Silver-Russell dwarfism and cystic fibrosis in a twin. Endocrine, chromosomal, dermatoglyphic, and craniofacial studies.


Vascular tumors of the liver in newborns. A pediatric emergency.


Intermittent arthritis following rubella vaccination. A three-year follow-up.


Health screening in school-age children. The physician and paramedical personnel.


Radiological case of the month.

Radiological case of the month.


Recurrent folic acid deficiency in sickle cell disease.


Metaphyseal and epiphyseal dysplasia with unusual facies and cataract.


Severe pulmonary involvement in visceral larva migrans.


Pseudohypertrophic muscular dystrophy. A report of two generations in a Thai family.


Hysterical dermatitis factitia.

Hysterical dermatitis factitia.


Swyer-James syndrome. (Unilateral hyperlucent lung) in children.


The upper limb cardiovascular syndrome.

The upper limb cardiovascular syndrome.


Triglyceride abnormality in infantile hypothyroidism.


Holt-Oram syndrome.

Holt-Oram syndrome.


Transferrins, haptoglobins, and ceruloplasmins among tribal groups of Madagascar.


Diagnosis of streptococcal diseases.

Diagnosis of streptococcal diseases.


Immunoglobulins in the Eastern Carolines.


Bioassay of kinship in Micronesia.

Bioassay of kinship in Micronesia.


Red cell isozymes in the Eastern Carolines.


Decreased odontometric sex difference in individuals with dental agenesis.


Morphologic characteristics of the Alaskan Eskimo dentition. 3. Number of cusps on the upper permanent molars.


Study on some genetic traits of Tibetans at Chandragiri, District Ganjam, Orissa.


A-B-O groups of Chacma baboons (Papio ursinus, Kerr) in South Africa.


Effect of timing and duration of the syncardial pressure pulses of skin temperature and plethysmogram of the legs.


Device for controlled rapid localized cooling.


The future of psychiatric education.

The future of psychiatric education.


Western humanism, modern liberal politics, and psychiatric training; friends or foes?


A comprehensive alcoholism program in the Army.


Male transsexualism: uneasiness.

Male transsexualism: uneasiness.


Playroom setting for diagnostic family interviews.


The effect of interview language on the evaluation of psychopathology in Spanishh-American schizophrenic patients.


Psychiatric treatment for nursing home patients: drug, alcohol, and milieu.


The teaching of psychiatry to medical students.


A unified system of care: blueprint for the future.


Medical students view clinical psychiatry.


Psychiatry in the undergraduate medical curriculum.


A test of clinical learning by medical students.


Psychiatry in the functionally organized undergraduate curriculum.


A medical interviewing course: objectives, techniques, and assessment.


Teaching communication skills in medical school.


Psychiatry in undergraduate medical education.


Evaluation of the SAID teaching program.


Amnesia and competency to stand trial.

Amnesia and competency to stand trial.


Legal services as a tool in treating the addict.


Computer assignment of psychotropic drugs.


Use of alcohol by addict and nonaddict populations.


The 24-hour serum lithium level as a prognosticator of dosage requirements.


Contradictions in the alcoholism criteria.


Lobotomies defended.

Lobotomies defended.


Viet Nam: the Board of Trustees steps out of bounds.


Compulsive water drinking.

Compulsive water drinking.


The weed system and psychiatry.

The weed system and psychiatry.


On being useful: the nature and consequences of psychological research on social problems.


A science of the South Pacific. Analysis of the character structure of the Peace Corps volunteer.


Baccalaureates in psychology 1969 and 1970.


National Board of Examiners in psychology.


Behavioral adaptations and biometrical genetics.


Tracheal stenosis following cuffed tube tracheostomy. Anatomical variation and selected treatment.


Replacement of superior vena cava with autogenous tissue. An experimental study.


Hemodynamic observations during and after pulmonary artery banding.


Superior vena caval obstruction secondary to fibrosing mediastinitis.


Serial ejection times in patients requiring multiple aortic valve replacements.


A simple, safe, and rapid technique for the management of recurrent coarctation of the aorta.


Multiple transections of the thoracic aorta secondary to blunt trauma.


Use of the ulnar artery for monitoring arterial blood pressures and blood gases.


Tube milking device.

Tube milking device.


The importance of defining location and staging of superior pulmonary sulcus tumors.


Empyema of the thorax then and now. A study of 122 cases over four decades.


Anaerobic empyema thoracis. The role of anaerobes in 226 cases of culture-proven empyemas.


Booster immunization against rubella in adult women.


Long-term low dose melphalan treatment of multiple myeloma.


Scleroderma-like lesions and the carcinoid syndrome.


Versatility of adrenal photoscanning. Diagnosis of unilateral adrenal failure.


Disseminated intravascular coagulation in trypanosomiasis.


Statement on hypoglycemia.

Statement on hypoglycemia.


Simultaneous block proximal and distal to His bundle. An example of concealed "concealed conduction".


Atrioventricular dissociation.

Atrioventricular dissociation.


Renovascular hypertension.

Renovascular hypertension.


The national need for research training.


Drugs and the doctor-patient relationship.


Standards for graduate medical education.


Microdetermination of mesitylenic acid in human urine.


Manganese binding in rat bile.

Manganese binding in rat bile.


Developmental changes in microtubule protein of chick brain.


Flavine specificity of enzyme-substrate intermediates in the bacterial bioluminescent reaction. Structural requirements of the flavine side chain.


Analysis of oxygen equilibrium of hemoglobin and control mechanism of organic phosphates.


Accessibility of the carbohydrate moiety of rhodopsin.


Light-stimulated incorporation of N-ethylmaleimide into coupling factor 1 in spinach chloroplasts.


Adenosine diphosphate translocation in mitochondria. Nature of the receptor site for carboxyatractyloside (gummiferin).


Initial reactions in the oxidation of ethylbenzene by Pseudomonas putida.


N-terminal sequence of the eucaryotic in vitro product made upon translation of satellite tobacco necrosis virus ribonucleic acid.


Hybridization studies with nucleic acids from murine myeloma. Comparison of pulse-labeled ribonucleic acid prepared from four different tumors.


Structure and activity in chemical carcinogenesis. Comparison of the reactions of 7-bromomethylbenz(a)anthracene and 7-bromomethyl-12-methylbenz(a)anthracene with mouse skin deoxyribonucleic acid in vivo.


A thermostable enolase from the extreme thermophile Thermus aquaticus YT-1.


Effect of proteases and of crude phospholipases on steroid glycosyltransferases from rabbit liver.


Properties of a stable cell-free esterase from soil.


L-phenylalanine ammonia-lyase (maize and potato). Evidence that the enzyme is composed of four subunits.


Intrinsic optical activity of retinal isomers. Implications for the circular dichroism spectrum of rhodopsin.


Carbon-13 nuclear magnetic resonance spectroscopy of oxytocin, related oligopeptides, and selected analogs.


The use of exogenous  -aminolaevulinic acid for the studies of the regulation of haem synthesis in rabbit reticulocytes.


The effect of heterologous transferrin on the uptake of iron and haem synthesis by bone marrow cells.


Isolation of D-erythro-neopterin 2':3'-cyclic phosphate from Photobacterium phosphoreum.


Glycoprotein biosynthesis. VI. Regulation of uridine diphosphate N-acetyl-D-glucosamine metabolism in bovine thyroid gland slices.


The presence of lipid-soluble selenium compounds in marine oils.


Secretion and protein metabolism in the rat pancreas in vitro.


Formation of electrophilic N-acetoxyarylamines in cytosoles from rat mammary gland and other tissues by transacetylation from the carcinogen N-hydroxy-4-acetylaminobiphenyl.


Scoliosis.

Scoliosis.


Studies on phytohemagglutinins. 8. A phytohemagglutinin receptor from human erythrocytes.


Safe prescribing in liver disease.

Safe prescribing in liver disease.


Chemical contamination of stored blood.

Chemical contamination of stored blood.


Safer motoring.

Safer motoring.


A ball in the eye.

A ball in the eye.


Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. Six female patients with systemic lupus erythematosus (S.L.E.) have been treated with chlorambucil. In five the decision was taken after failure by corticosteroids to control progressive renal disease in the face of unacceptable corticosteroid toxicity. After the introduction of chlorambucil renal function improved and all patients remain well six, six, five, three, and two-and-a-half years later, respectively. On renal biopsy five had focal proliferative glomerulonephritis. Repeat biopsy in two cases showed quantitative improvement. The sixth patient was treated with chlorambucil because of failure by corticosteroids to control peripheral vascular lesions and haemolysis and she remains well four years later. In four patients is it probable that amenorrhoea was related to chlorambucil treatment, but there were no other important side effects although one patient developed a degree of marrow depression during treatment. Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis.


Plasma renin levels and vascular complications in hypertension. Plasma renin levels, measured in 39 untreated patients in 1967, under conditions of sodium loading and sodium depletion have been related to the incidence of stroke and myocardial infarction. Renin levels were not significantly different in patients with or without vascular complications. Out of 13 patients with persistently low renin levels 6 had suffered either a stroke or a myocardial infarction and 7 had not. Plasma renin levels were also measured in 116 treated hypertensive patients. There was no relation between plasma renin level and vascular complications. It is concluded that levels of plasma renin are not a reliable index of the probability of hypertensive patients suffering a stroke or myocardial infarction.


Effects of clonidine withdrawal: possible mechanisms and suggestions for management. A severe rebound rise in blood pressure with agitation and insomnia had been noted in five patients when they had previously ceased clonidine (Catapres) This has been shown to be reproducible in these patients and to be associated with a significant increase in urinary catecholamine excretion. The blood pressure can be controlled and the symptoms alleviated promptly by alpha and beta adrenergic receptor blockade using intravenous phentolamine and propranolol.


Bacteroides infection among hospital patients. In an 18-month period a total of 118 isolates of Bacteroides species, mainly Bacteroides fragilis, were grown from 112 hospital patients with various conditions. The infections were severe and were associated with serious operations such as intestinal surgery for carcinoma and postpartum hysterectomy. Blood cultures were often found to be positive too late in the course of infection for prompt and successful antibiotic therapy to be given. All the Bacteroides species tested were sensitive to clindamycin and co-trimoxazole. We suggest that clindamycin should be added to an empirical antibiotic regimen for the treatment of patients prone to the infection.


Amiloride in primary hyperaldosteronism with chronic peptic ulceration.


Unilateral renal hypoplasia with hypertension (Ask-Upmark kidney).


Diverticulitis of the transverse colon.

Diverticulitis of the transverse colon.


Serum lithium estimations.

Serum lithium estimations.


Effect of respiration on Parkinsonian tremor.


Acute pancreatitis in mycoplasma pneumoniae infections.


Anaesthetic contamination.

Anaesthetic contamination.


Treatment of depression in general practice.


Coeliac disease and schizophrenia.

Coeliac disease and schizophrenia.


Pruritus vulvae.

Pruritus vulvae.


Social workers and family doctors.

Social workers and family doctors.


Dangers of gas fires.

Dangers of gas fires.


Contraceptives on the N.H.S.

Contraceptives on the N.H.S.


Pityriasis rosea in sisters.

Pityriasis rosea in sisters.


Chondromalacia patellae.

Chondromalacia patellae.


Mute of malady.

Mute of malady.


Assessment of acid-base disturbances.

Assessment of acid-base disturbances.


Post-neonatal sudden unexplained death in a California community. To gain further insight into the problem of infant sudden death, a study was undertaken to investigate a complete series of cases of infant sudden unexplained death that occurred during a seven-year period in Sacramento County. Needed information was abstracted from autopsy records, Medical Examiner's records and death certificates. The average death rate for the seven-year period was 1.7 for 1,000 live births. Average age at time of death was 2.8 months. There were no records of sudden death among infants over the age of eight months. Higher than average death rates were observed within many of the low socioeconomic areas of Sacramento County. Also, sudden unexplained deaths appeared to occur more frequently in the winter months than in the spring, summer or fall. In over half the cases the infants had a cold, the sniffles, or other respiratory tract congestion within two weeks of the date of death, which seems to support the oft-quoted contention concerning the possibility of nasal obstruction which could initiate the fatal apnea. An additional notable finding was the very frequent occurrence of petechial hemorrhage in the thymus, heart, and lung tissues. The unique age distribution of these deaths in combination with the high frequency of low socioeconomic groups and the frequency of minor respiratory ailment would suggest approaches that can be taken to identify infants at high risk and thus initiate effective community health programs for prevention.