Aversion therapy.

Aversion therapy.


Behavior therapy: a clinician's view.

Behavior therapy: a clinician's view.


Combined use of behavioral and psychoanalytic approaches in the treatment of severely disturbed adolescents.


Psychodynamic theory and conditioning therapy.


Biogenic amines and their impact in psychiatry.


Interactions between learned and physical factors in mental illness.


The impact of scientific models on clinical psychopharmacology: a psychiatrist's view.


The impact of scientific models on clinical psychopharmacology: a pharmacologist's view.


Scientific models for psychopathology in the 1970's.


The issues of autonomy and aggression in the three-year-old: the Utku Eskimo case.


Development in middle childhood.

Development in middle childhood.


Pre- and postpubertal personality and adult psychologic functioning.


Coping and growth in adolescence.

Coping and growth in adolescence.


Maternal and child behaviors: a review of data from the Berkeley Growth Study.


The Fels study: some contributions to personality development and achievement in childhood and adulthood.


The levels of sulphobromophthalein (BSP) in thoracic duct lymph and blood serum in patients with cholestasis.


Natural history of male psychologic health. I. The adult life cycle from 18-50.


Personality development from adolescence to adulthood in the Oakland Growth and Guidance Studies.


Associations of pigment markers with antibiotic resistance markers in chromogenic mutants of Staphylococcus aureus.


Analog model of BSP kinetics in the organism of healthy subjects.


Studies on the physiology of the hibernating hedgehog. 15. Effects of seasonal and temperature changes on the in vitro glycerol release from brown adipose tissue.


On the thickness of the Hepatic oil-body membrane.


An electron microscopic study on the thymus epithelium of the snake (Vipera berus L.).


Aseptic cultures of seed plants at various sucrose concentrations with and without gibberellin.


Colchicine effects and colchicine-induced polyploidy in Betula.


Studies on the physiology of the hibernating hedgehog. 16 Variation in the nuclear sizes of cells of the supraoptic nucleus of hedgehog during circadian, hibernation, and annual cycles.


Wax esters: major marine metabolic energy sources.


Relations between lipid composition and permeability of membranes.


The effects of starvation and of cold stress on clearing factor lipase activity and triglyceride fatty acid utilization in rat heart.


Chairman's introduction: remarks on biochemical mapping of the nervous system.


The synthesis of prostaglandins in human platelets.


The acceptability of contraceptive sterilization among U. S. couples: 1970.


Studies on the excretion of a 14C/32P-polyene phosphatidylcholine in the bile.


Condoms--a new look.

Condoms--a new look. There are many advantages to the condom, a contraceptive which is holding its own in the US market.  This is the case although the product is not advertised as much as foam and is hardly promoted at all by physicians.  With a major promotional effort on the part of manufacturers and family planning programs there might be a considerable increase in condom use.  This could be important particularly in the prevention of premarital pregnancies and venereal disease among younger teenagers.  Increased promotion would necessitate changes in current state laws which now restrict the sale, advertising, or display of condoms.  Despite its advantages, the "sensation" objection is unquestionably valid, and more research is required into the potential extended use-effectiveness of thinner, more sensitive condoms compared with the thicker products which are freer from minor defects.  Most of the world's condoms are manufactured in the US, the UK, and Japan.  The Japanese are the world's most innovative and imaginative manufacturers and promoters of condoms.  Thus, the Japanese condoms tend to dominate most markets in which they are freely allowed.  In selecting condoms for use in a family planning program, or for other efforts by family planning professionals to promote condom use, the selection of brands can be critical.  The basic variations in American condoms include differences in the material from which they are made, their shape, whether or not they are lubricated, their color, and their size.  American manufactured condoms are made either of animal membrane or latex rubber.  There are 2 basic variations in common shape in the US:  the reservoir end; and the preshaped condom.  Condoms are available dry and lubricated.  Most users prefer lubricated brands.  The 2 types of lubricants are moist and silicone.  The role of color has been very little investigated.  Evidence from other countries suggests a strong preference for condoms in color rather than plain white or transparent condoms.  There are few significant differences in size among US brands except that skin condoms are larger than latex condoms because they will not stretch.  In the US condom quality control is supervised by the Food and Drug Administration, and its surveillance is strict.  In general, the quality of condoms in America is good.  The packaging factor can have a significant effect on the ultimate effectiveness of condoms, since minor damage to the condom between purchase and use is probably a more significant factor than defects in the manufacturing process.


Public opinion trends: elective abortion and birth control services to teenagers.


Abortion: odyssey of an attitude.

Abortion: odyssey of an attitude.


A philatelic view.

A philatelic view.


Sexual experience of young unmarried women in the United States.


The measurement by serological means of the impact of the Hong Kong/68 influenza virus on a population.


A study on aflatoxins in Turkish pistachio nuts.


Malrotation after femoral shaft fractures.


Haemangioma in the knee-joint.

Haemangioma in the knee-joint.


Results of total arthroplasty of the hip in geriatric patients.


Necrosis of the femoral head occurring in association with corticosteroid medication.


Necrosis and deformation of the femoral head following fracture of the femoral neck--a morphological study.


The results of a modified version of Voss' operation in the treatment of arthrosis deformans for the hip.


Congenital luxation of the knee.

Congenital luxation of the knee.


Discitis in children.

Discitis in children.


The long-term results of intertrochanteric osteotomy of the femur.


Recurrent anterior dislocation of the shoulder.


Disturbed gait caused by an aponeurotic fibroma above the knee.


Thirty years with a complete elbow prosthesis.


The pathogenesis of the complications of medial fractures of the neck of the femur in the light of the results of a follow-up study.


Thymolipoma.

Thymolipoma.


Postsurgical treatment of tracheal of bronchial anastomoses.


Electric stimulation in a case of median-nerve reconstruction.


Haemorrhagic necrosis of the skin as a complication of anticoagulant therapy.


The importance of venous thrombosis in acute intestinal infarction.


How well do autoclaves function?

How well do autoclaves function?


Comments on "febrile convulsions as a problem in waiting times".


Febrile convulsions as a problem in waiting times.


Letters to the editors; Febrile convulsions as a problem in waiting times.


Proceedings: Ultrastructure study of the chronic experimental epileptic focus.


Proceedings: Epileptogenic effects of cobalt in Macca mulatta: unilateral and bilateral cortical foci.


Proceedings: Miniature postsynaptic potentials (MPSPs) in normal and epileptogenic cortex.


Proceedings: Examination of neural mechanism involved in photogenic seizure susceptibility in epileptic Senegalese baboon: Papio papio.


Proceedings: Agenesis of the corpus callosum: an electroencephalographic study.


Proceedings: Studies of "small spikes" with depth electrography.


Proceedings: Epileptic sensitization: acute effect of callosal section on "independent" spikes in man.


Proceedings: Compressed spectral displays in epileptic patients.


Proceedings: The syndrome of acquired aphasia, EEG abnormalities with or without convulsive disorder in children.


Proceedings: The prognosis of convulsive disorders in Rochester, Minnesota 1935-67.


Proceedings: Laminar DC analysis of acetylcholine-induced epileptiform activity in chronically undercut cortex.


Proceedings: Toxic encephalopathy with seizures secondary to ingestion of an explosive material: Composition C-4. A clinical and electroencephalographic study.


Proceedings: A method of modifying the rapidity of cobalt-induced epileptogenesis.


Proceedings: Vagotonic seizures.

Proceedings: Vagotonic seizures.


Proceedings: Spontaneous antidromic spikes from axons in cortical penicillin foci.


Cross-linkage in lymphocyte transformation.


The metabolic activity of bursal and thymic cells.


Effect of DDT on antibody response to typhoid vaccine in rabbits and man.


In vitro regulation of the anamnesic antibody response upon addition of heterologous antigens to primed lymphoid cells.


Expression of H-2 antigens during growth of cultured tumor cells.


Immobilization of lymphocytes at surfaces by alloantibodies.


Ability to smell solution of sodium cyanide in Oraons and Mundas of Ranchi (India).


The efficacy of cambendazole against cestode and nematode infestations in sheep and cattle.


Gonadotrophic hormone activity in female Angora goats exhibiting normal and aberrant reproductive activity.


Further observations on the involution of the post partum uterus of the ewe.


Representative rumen sampling.

Representative rumen sampling.


Pale, soft exudative pork, porcine stress syndrome and malignant hyperpyrexia--an identity?


Immunization of sheep against pasteurellosis.


Morphology of the free-living stages of Nematodirus spathiger with some observations on their development under laboratory conditions.


The use of antibiotics in animal feed.

The use of antibiotics in animal feed.


A contribution towards the diagnosis of trichostrongylosis in flocks of sheep under field conditions.


Today's meat hygiene and inspection.

Today's meat hygiene and inspection.


A representative survey of the pig industry in the Republic of South Africa.


Observations of veterinary interest during a visit to Western Germany.


Some aspects of the treatment of shock in animals.


Some haematological values in five species of game.


Considerations on large scale vaccination of free-living game.


Worm control under flock conditions in the grassveld areas of the eastern Cape and eastern Organge Free State.


Some observations on Crysticercus bovis at Matsapa Abattoir in Swaziland.


Notoedres cati (Hering, 1838) infestation of the cheetah: preliminary report.


Letter to the editor: Some meat inspection findings at Matsapa Abattoir in Swaziland.


Herpesvirus saimiri malignant lymphoma in spider monkeys. A new susceptible host.


Betel quid carcinogenesis in the baboon.


Single placentas in the rhesus monkey.

Single placentas in the rhesus monkey.


Erythrocyte survival in chimpanzees, gibbons and baboons.


Dissociative anesthesia in Macaca mulatta. Clinical evaluation of CI 744.


An observation of long-term experimental obesity and diabetes mellitus in the monkey.


Inhibition of influenza viral glycoprotein synthesis by sugars.


Concentration and purification of the male-inducing substance from Volvox aureus M5.


Sensitivity of amoebae to chloroquine or erythromycin.


Poria weirii-inhibiting and other phenolic compounds in roots of red alder and Douglas-fir.


Electrophoretic indices of serum proteins in healthy newborn infants in Recife.19h.


Study of the bimodal frequency distribution of the relative concentration of hemoglobin S in heterozygous carriers.


Experimental chemotherapy of schistosomiasis. VI. Egg suppressive activity of thiosinamine.


Combined deficiency anemia in chronic disease.


Lecithin cholesterol acyl transferase (LCAT).


Number of segregation classes as a function of number of loci in ordered tetrad analysis.


Microscopical anatomy of the lymphatic circulation of the tendons.


The lymphatic system of the great blood vessels in normal, pathologic and experimental conditions.


Interference with prolactin release and the maternal behavior of female rats.


Androgen modification of behavioral responsiveness to estrogen in the male rat. The behavioral responsiveness of male rats to large doses of exogenous estrogen was investigated through female behavior tests (mean lordosis scores).  The animals were either castrated at birth or 60 days after birth, and exposed to injections of androgens begun either at birth or at 14 days of age.  Estradiol benzoate (EB) was given daily (200 mcq) when the rates were about 90 days old.  All rats in all groups exhibited lordosis responses after EB injections; those rats castrated at birth and receiving no androgens before day 14 exhibited lordosis responses earlier and achieved highest lordosis scores compared with rats  exposed to either endogenous or exogenous androgen during the neonatal period.  High doses of testosterone administered during the differentiation period reduced the quality and frequency of lordosis responses; apparently male estrogen responsivity can be decreased by exposure to androgen(exogenous) during the neonatal  period as well as increased by neonatal castration.  There are 2 distinguishable influences of neonatally present androgen on behavioral responsivity to estrogen: 1) a general suppression of all estrous behaviors, 2) delay in the appearance of these behaviors.


The effect of gonadal hormones in infancy on maternal behavior in the adult rat.


Effects of adrenalectomy on open-field behavior in rats.


Effects of vasopressin on active and passive avoidance behavior.


The effects of estrogen and progesterone on copulation in female quail (Coturnix coturnix japonica) housed in continuous dark.


The effects of progesterone and its metabolites on the induction of sexual receptivity in rats.


Behavioral and other systemic effects of cortisol-21 sulfate.


Overeating induced by progesterone in the ovariectomized, adrenalectomized rat.


Macrophage migration inhibition test: a critical examination of the technique using a polythene capillary tubing micromethod.


Two new species of Toxocara from viverrid hosts.


Life cycle of a new echinostome from Egypt, Echinostoma liei sp.nov. (Trematoda: Echinostomatidae).


Antagonism of Echinostoma liei (Trematoda: Echinostomatidae) against the trematodes Paryphostomum segregatum and Schistosoma mansoni.


Immunity to coccidiosis: maternal transfer in Eimeria maxima infections.


A rational approach to the serial culture of malaria parasites: evidence for a deficiency in RNA synthesis during the first cycle in vitro.


The effects of temperature and other factors upon the establishment and survival of Pomphorhynchus laevis (Acanthocephala) in goldfish, Carassius auratus.


Observations on the envelope surrounding Moniliformis dubius (Acanthocephala) in the intermediate host, Periplaneta americana.


Fine structural changes in Eimeria tenella, from infections in chick embryos and chickens, after exposure to the anticoccidial drug robenidene.


Ultrastructural studies on microfilariae (Nematoda: Filarioidea).


Effects of variations in temperature on infective larvae and their relationship to inhibited development of Obeliscoides cuniculi in rabbit.


[The results of treatment of pituitary dwarfism with human growth hormone (author's transl)].


An investigation of certain factors concerned in the aetiology of depersonalization.


The experienced reality of hallucinations and other psychological phenomena. An empirical analysis.


The reliability of different aspects of the experienced reality of hallucinations in clear states of consciousness.


Transitional phenomena: frequency, forms and functions of specially loved objects.


Varieties of adolescent 'separation conflicts'.


Helplessness in the helpers.

Helplessness in the helpers.


Myth and the democratic process.

Myth and the democratic process.


Pregnancy and motherhood: interaction between fantasy and reality.


Relationship patterns and their expression in the doctor-patient relation in asthmatics.


Compulsive gambling and the family.

Compulsive gambling and the family.


A questionnaire study of risk-taking in psychiatric patients.


The use of the double dyad grid in the clinical setting.


A comparison of adjusted and maladjusted couples using the double dyad grid.


Conceptual changes during recovery from anorexia nervosa.


Editorial: Safety and sanity.

Editorial: Safety and sanity.


Ventricular fibrillation threshold of healthy dogs to 50Hz current in relation to earth leakage currents of electromedical equipment.


A swivel walker for paraplegics: medical and technical considerations.


Standards in surgical implants: the present status.


Digestive endoscopy symposium.

Digestive endoscopy symposium.


Variation in ocular motor dominance.

Variation in ocular motor dominance.


Colour, colour saturation, and pattern induced by intermittent illumination: an initial study.


Pupil size for complex adapting field configurations.


Further studies on the adaptation to artificially-induced aniseikonia.


The influence of detergents on the activity of 5'-nucleotidase (EC 3.1.3.5) in rat liver homogenates.


Effect of vitamin D on brush border alkaline phosphatase in the rat small intestine.


Gd(minus)A variant of glucose-6-phosphate dehydrogenase in an Algerian family.


A rare constellation of serum cholinesterase genetic variants.


Variable starch gel electrophoretic pattern of the enzyme 6-phosphogluconate dehydrogenase in a family of donkeys (Equus asinus L.).


The effect of genic time-factors upon growth and differentiation as observed in certain snail shells, bivalves and plants.


Mitotic and meiotic chromosomes of the variable hare (Lepus timidus L.), the common hare (Lepus europaeus Pall.) and their hybrids.


A case of spontaneous haploidy and notes on triploid-diploid mosaics in rabbit embryos.


The role of chromosomal rearrangement in mammalian speciation with special reference to Cetacea and Pinnipedia.


An analysis of growth capability in full sib families of salmon (Salmo salar L.).


Culling rates in daughters of sires with a translocation of centric fusion type.


A malformed pig with a normal female karyotype.


Chromosome studies of Mustela putorius in tissue culture.


The temperature influence on the spontaneous mutation rate. II. Investigation by the aid of waxy mutants.


Aspects of diapause and its genetics in northern drosophilids.


Genetics of Zoarces populations. II. Three loci determining esterase isozymes in eye and brain tissue.


The effect of cyclamate and saccharin on the chromosomes of a Chinese hamster cell line.


Cytological studies in Atlantic salmon from Canada, in hybrids between Atlantic salmon from Canada and Sweden and in hybrids between Atlantic salmon and sea trout.


The fluorescence pattern of a human Yq Plus chromosome.


The stemline idiogram of the MSWBS tumor of the mouse and the problem of centric fusion.


Comparative chromosome studies in mongooses (Carnivora, Viverridae). I. Idiograms of 12 species and karyotype evolution in Herpestinae.


Studies on spontaneous abortions. Fluorescence analysis of abnormal karyotypes.


Origin of triploidy in human abortuses.

Origin of triploidy in human abortuses.


Considerations on phase-change and decorations in snail shells.


Type of dominance modification in schizophrenia.


A family with 15-22 translocation.

A family with 15-22 translocation.


Condensation of chromosomes during meiotic prophase. Whole mount electron microscopy of the spermatogenesis in Omocestus.


Mortality frequencies in hatchery-reared salmon (Salmo salar L.).


Correlation between Y chromosome length and fluorescence intensity of Y chromatin on interphase nuclei.


Populations in a seasonal environment.

Populations in a seasonal environment.


Synthesis of synaptic glycoproteins. II. Delayed labelling of the glycoproteins of synaptic vesicles and synaptosomal plasma membranes.


Protective effect of mouse 7S nerve growth factor protein and its alpha subunit on embryonic sensory ganglionic cells during dissociation.


A modified erythropoietin bioassay using protein deprived mice.


Schistosomal pulmonary hypertension: a case report.


Veno-occlusive disease of the liver and Australia antigen.


The second heart sound in ventricular septal defect.


Dosage pumps to control flow of ion exchange resin through a column.


Effect of various hormones on red cell production in mice.


A dialysis apparatus for measuring permeation rates through polymer films.


On the mechanism of ion exchange in crystalline zirconium phosphates. VI. The effect of crystallinity of the exchanger on Na+/H+ exchange.


Genetically determined electrophoretic variants of phosphoglucose isomerase and 6-phosphogluconate dehydrogenase in Zoarces viviparus L.


The Finnish population structure. A genetic and genealogical study.


An attempt to estimate the magnitude of additive genetic variation of body size in the guppy-fish, Lebistes reticulatus.


Chromosome breaking effect of a gasoline additive in cultured human lymphocytes.


Isozyme polymorphism in three species of land snails.


Labelling of lymphocyte nuclei and chromosomes with tritiated thymidine in megaloblastic anemia.


Presumptive Y-15 and Y-22 translocation in two families.


Partial specific volume measurements by the density gradient column method.


Measurement of translational and rotational diffusion coefficients by laser light scattering.


The isopiestic method.

The isopiestic method.


Calorimetry.

Calorimetry.


Measurement of protein-small ion interactions with ion-specific electrodes.


High precision capillary viscometry.

High precision capillary viscometry.


Protein polypeptide chain molecular weights by gel chromatography in guanidinium chloride.


Flow birefringence.

Flow birefringence.


Measurement of molecular weights by electrophoresis on SDS-acrylamide gel.


Electric birefringence.

Electric birefringence.


Dielectric dispersion measurement of dielectric constant and conductivity.


The determination of activity coefficients from distribution measurements.


The strength of hydrogen bonding: infrared spectroscopy.


Dilatometry.

Dilatometry.


Hydrogen-tritium exchange.

Hydrogen-tritium exchange.


Potentiometric titrations and conformational change.


Measurements at high pressure.

Measurements at high pressure.


The preparation of guanidine hydrochloride.


Infrared spectroscopy--conformation.

Infrared spectroscopy--conformation.


Raman spectroscopy.

Raman spectroscopy.


Nanosecond fluorescence spectroscopy of macromolecules.


Vapor pressure osmometry.

Vapor pressure osmometry.


Environmentally sensitive groups attached to proteins.


High-resolution proton magnetic resonance spectroscopy of selectively deuterated enzymes.


Magnetic susceptibility.

Magnetic susceptibility.


Magnetic densimetry: partial specific volume and other applications.


Matter and energy balance in normal man.


Considerations on energy requirements in space.


Dietary components that yield energy.

Dietary components that yield energy.


Vitamin and mineral allowances.

Vitamin and mineral allowances.


Immunology of ageing tissue.  Introduction.


Amyloid degeneration and tuberculosis in the aged.


Age-dependent immunophysiologic correlates of chronic respiratory disease.


Iron-deficiency anemia in mink fed raw marine fish. A five year study.


Departure from handwriting system.

Departure from handwriting system.


Quantitative analysis of skin color from melanin content of superficial skin cells.


The use of differential scanning calorimetry in the identification of synthetic fibres.


Statistical treatment of pellet dispersion data for estimating range of firing.


Forensic psychiatry in the legal defense of murder.


Determination of propoxyphene in biological materials by ultraviolet spectrophotometry and gas chromatography.


The determination of excipient sugar diluents in illicit preparations containing heroin by gas chromatography.


Systems analysts look at the crime laboratory.


The medical examination of cases of rape.


Nonanatomic postmortem techniques: postmortem serology.


Dental identification of disaster victims by a dental disaster squad.


Some physical properties of a large number of window glass specimens.


Neutron radiography with 252-Cf in forensic science.


Identification of single-stranded copper wires by nondestructive neutron activation analysis.


Forensic Medicine.

Forensic Medicine.


Suicidal insulin poisoning with nine day survival: recovery in bile at autopsy by radioimmunoassay.


The phenomenon of adolescent addiction.

The phenomenon of adolescent addiction.


Use of chemical determinations on vitreous humor in forensic pathology.


Experimental injuries of the eye caused by a tear gas pen gun loaded with ortho-chlorobenzalmalononitrile.


The establishment of a therapeutic community within a women's correctional facility.


The complexities of identifying the modern typewriter.


A new look at qualifying expert witnesses and the doctrine of privilege for forensic scientists.


Blood alcohol concentrations in drinking drivers in Tucson, Arizona, 1967-1971.


Phenothiazines: metabolism and analytical detection.


A basic training program for forensic drug chemists.


Dangerous drugs: adulterants, diluents, and deception in street samples.


Examination of firing pin impressions by scanning electron microscopy.


Toxicological data for fatalities due to carbon monoxide and barbiturates in Ontario--a 4-year survey, 1965-1968.


Identification and determination of heroin in illicit seizures by combined gas chromatography-infrared spectrophotometry.


The application of scanning electron microscopy to the forensic evaluation of vehicular paint samples.


Determination of chloral hydrate and trichloroethanol in biological tissue.


Methods for the detection and determination of ethchlorvynol in biological tissue.


A general approach to perticide residue analysis.


The specificity of the Duquenois color test for marihuana and hashish.


Tryptic glycopeptides of a mitogenic erythro- and lympho-agglutinating phytohemagglutinin (PPHA) from red kidney beans (Phaseolus vulgaris).


Isopentenyladenosine inhibits transport of purine and pyrimidine nucleosides and growth of mouse embryo cells.


Unusual sulfur-containing amino acids in the urine of homocystinuric patients: III. Homocysteic acid, homocysteine sulfinic acid, S-(carboxymethylthio) homocysteine, and S-(3-hydroxy-3-carboxy-n-propyl).


Cation interaction selectivity sequences for an S37 ascites cell amino acid transport system.


Studies on succinate dehydrogenase: XXI. Quaternary structure of succinate dehydrogenase.


Labeling of brain DNA by 3-H-thymidine during learning.


Electron-transfer factors in psychosis and dyskinesia.


Resonant energy as a mechanism for mental activity.


Autoradiographic study of 3-H-thymidine incorporation into brain DNA during learning.


Stimulatory effect of tricarboxylic acids on ATP formation in mitochondria.


Phospholipid configuration and thermal denaturation of DNA in rat liver nucleus chromatin.


Purification and properties of D-lactate dehydrogenase from Mycobacterium sp. 279.


Effect of divalent metal ions upon the acylation of sn-glycerol-3-phosphate by rat brain microsomes.


Decreasing in vitro cholesterolgenesis by the in vivo administration of the fat soluble vitamins.


The hypochromism of dinucleotides.

The hypochromism of dinucleotides.


Brain DNA changes during learning studied by administration of 5-iodo-2'-deoxyuridine.


Biological significance of serum acid glycoproteins: a hypothesis.


A note of F. W. Cope's paper "Evidence from activation energies for superconductive tunneling in biological systems at physiological temperatures".


Investigation of rabbit aldolase isoenzymes with irradiated fructose-1,6-diphoshate.


Editorial: Roentgen demonstration of coronary circulation.


Interaction of cysteamine oxygenase with tiron.


Coronary arteriography: a perspective for radiologists.


Nonselective coronary arteriography.

Nonselective coronary arteriography.


Biosynthesis of novobiocin by Streptomyces niveus. Streptomyces niveus in a chemically defined medium requires the inclusion of Krebs cycle acids for good growth. These acids are used in preference to glucose, and this results in diauxic growth. Studies with washed cells, cell-free extracts, and mutants of S. niveus were performed to determine the mode of synthesis of the individual ring systems of novobiocin and their linkage. A pathway for novobiocin synthesis is proposed on the basis of these experiments.


Induction of chloramphenicol metabolism by phenobarbital. The induction of hepatic microsomal enzymes leading to more rapid metabolism of antibiotics has been demonstrated in only a few prior studies. We have studied the induction of chloramphenicol metabolism in an isolated rat liver perfusion model and in intact dogs. Using these methods, we have demonstrated that the clearance of chloramphenicol from serum is markedly increased after treatment of animals with phenobarbital. This was demonstrated to be a function of increased clearance of the drug by the liver, accompanied but not paralleled by increases in liver weight and biliary excretion by the rat liver. In intact dogs, small doses of chloramphenicol were not sufficient to demonstrate this fact, whereas a large test dose of 100 mg/kg showed markedly enhanced clearance after 1 week of oral phenobarbital administration. Prolongation of phenobarbital treatment or increased dose did not further increase the clearance, and chloramphenicol could not be demonstrated to enhance its own clearance. Human data on induction of enzymes is to date inconclusive.


Two new antimetabolites of biotin: alpha-methyldethiobiotin and alpha-methylbiotin. Two new antimetabolites of biotin were isolated from culture filtrates of Streptomyces lydicus: beta-methyldethiobiotin and beta-methylbiotin. (14)C-biotin or (14)C-pimelic acid was not incorporated into either of these antimetabolites by the growing culture. Neither of the compounds could substitute for the biotin requirement in Saccharomyces cerevisiae. Both compounds had a strong and rather specific antimicrobial effect against mycobacteria. Their antimicrobial activities were reversed by biotin. Both compounds had an affinity for avidin.


In vitro antimicrobial susceptibility of anaerobic bacteria isolated from clinical specimens. The minimal inhibitory concentrations of 601 clinical isolates of anaerobic bacteria to 10 different antimicrobial agents were determined by an agar-dilution technique. Nearly all strains were resistant to kanamycin and gentamicin, although moderate activity to both drugs was noted with Fusobacterium sp., anaerobic cocci, some strains of Bacteroides melaninogenicus, and nonsporeforming gram-positive bacilli. Chloramphenicol at 12.5 mug/ml inhibited all but three of the strains tested. Tetracycline at 6.25 mug/ml had high activity against all groups tested, with the exception that only 39% of strains of Bacteroides fragilis were inhibited at this concentration. Excluding certain species of Bacteroides, the majority of anaerobes were inhibited by penicillin at 3.1 mug/ml or less and by cephalothin at 12.5 mug/ml or less. Lincomycin at 6.2 mug/ml or less was active against nearly all strains. Erythromycin at a concentration of 3.1 mug/ml was active against B. fragilis; however, erythromycin was less active against the other groups. Most of the minimal inhibitory concentrations of lincomycin exceeded those of clindamycin by fourfold. Rifampin inhibited virtually all strains at 3.1 mug/ml.


Obligate parasitism of trachoma agent: lack of trachoma development in ethidium bromide-treated cells. Trachoma agent failed to develop in eukaryotic cells pretreated with ethidium bromide.


Surface manifestations of antibiotic-induced alterations in protein synthesis in bacterial cells. Scanning electron microscopy of changes in bacteria induced by antimicrobial agents which interfere with cell wall synthesis revealed morphological alterations which correlated well with their mechanism of action. The present studies were undertaken to investigate the presence and characteristics of alterations in surface morphology resulting from the action of antibiotics known to interfere with intracellular protein synthesis. Strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were exposed to kanamycin, chloramphenicol, and tobramycin during various phases of bacterial growth. A spectrum of morphological changes related to concentration of drug and duration of exposure was observed which was similar to those induced by penicillin or cephalothin. Cells were also exposed to sulfamethoxazole with similar results. The morphological abnormalities observed may be surface reflections of specific abnormalities of intracellular protein synthesis or may represent a final common pathway of druAg-induced injury at many sites within or on bacterial cells.


Neutropenia associated with cephapirin therapy. A case of neutropenia associated with cephapirin therapy is described. After discontinuation of cephapirin therapy, the neutrophil count returned to normal. Bone marrow examination revealed a marked reduction of polymorphonuclear leukocytes beyond the metamyelocyte stage and eosinophilia.


Standardized single-disc method for antibiotic susceptibility testing of anaerobic bacteria. A method was developed for determination of the antibiotic susceptibility of anaerobic bacteria by use of a single-disc diffusion technique and incorporation of the inoculum in pour plates. The method was standardized by correlation of zone diameters with minimal inhibitory concentrations determined in broth. Zone diameters could be used to approximate the minimal inhibitory concentrations of the seven antibiotics tested: ampicillin, bacitracin, carbenicillin, cephalothin, clindamycin, penicillin, and tetracycline.


Effect of hemodialysis and renal failure on serum and urine concentrations of cephapirin sodium. Six patients undergoing chronic hemodialysis and 10 patients with chronic renal insufficiency hospitalized for nondialytic therapy received 1.0 g of cephapirin sodium by the intravenous route. The concentrations of cephapirin in arterial and venous plasma, dialysate, venous blood, and urine were measured during the ensuing 6 hr. The serum half-life of cephapirin was 105 to 108 min for the dialyzed patients and 95.9 min for the nondialyzed patients. Dialysis removed 22.8% of the administered dose. Nondialyzed patients excreted 19.5% of the administered dose in the urine. The concentration of cephapirin in the urine of all nondialyzed patients exceeded 50 mug/ml. The recovery of cephapirin in the urine collected for 6 hr after injection was from 34 to 770 mg (mean 195 mg). To maintain a concentration of cephapirin in the blood and urine which exceeds the minimal inhibitory concentration for most gram-positive and gram-negative microorganisms, nondialyzed patients should receive 15 to 18 mg of cephapirin per kg every 12 hr. Dialyzed patients should receive the same dose just prior to dialysis and every 12 hr thereafter.


Pharmacological studies with 5-fluorocytosine. A cylinder plate bioassay for 5-fluorocytosine (5-FC) is described which permits determination of 5-FC concentrations in biological fluids in the presence of amphotericin B. Using this assay, we determined serum concentrations in 12 patients after a single dose of drug and in 8 patients receiving daily 5-FC at 6-hr intervals (4 to 120 days). Drug was detectable in serum as early as 0.5 hr and concentrations were measurable as long as 24 hr after a dose, regardless of renal function. Peak concentrations occurred 6 hr after the initial drug dose, but were seen between 1 and 2 hr after a dose in all patients receiving a minimum of 4 days of therapy. Mild to moderate renal impairment produced marked increases in peak 5-FC concentrations in the serum of a group of eight patients on three different dosage schedules. Five patients were studied before and after amphotericin B-induced renal insufficiency. Peak concentrations increased from 14 to 142% concomitant with the change in renal function. Parallel studies in rabbits confirmed the results in our patients. 5-FC half-life in the serum of 10 rabbits increased from 3.35 +/- 0.27 to 24.63 +/- 0.70 hr after experimentally induced acute renal failure. Concentrations of 5-FC in the cerebrospinal fluid of five patients ranged from 17 to 62 mug/ml and were 74.4 +/- 5.6% of simultaneously determined serum concentrations. The effect of renal function on 5-FC concentrations in cerebrospinal fluid was similar to that seen with serum.


Comparison of clindamycin, erythromycin, and methicillin in streptococcal infections in monkeys. Intravenous inoculation of a group A hemolytic streptococcus caused lethal infections in all of eight untreated monkeys. Intramuscular injections of clindamycin-2-phosphate in a daily dose of 25 mg/kg given in equal morning and afternoon doses for 10 days resulted in survival of all of eight monkeys. Similar results were observed with the same dose schedule of clindamycin hydrochloride given intragastrically; no fatalities occurred among eight monkeys. In monkeys receiving erythromycin stearate intragastrically or methicillin intramuscularly, three of eight and four of eight monkeys, respectively, died. Duration of both illness and positive blood cultures was greater in the erythromycin- and methicillin-treated survivors than in the clindamycin-treated monkeys. The differences in results between clindamycin and erythromycin could not be correlated with serum antibacterial activity levels, which were similar, or with minimal inhibitory concentrations, which were 0.02 mug/ml with both antibiotics. With methicillin, however, the minimal inhibitory concentration was 0.16 mug/ml and serum antibacterial activity varied from titers of less than 1:2 to 1:8. As in previous studies of staphylococcal infections in monkeys with the same antibiotics, in vitro susceptibility data and serum antibacterial activity did not completely correlate with in vivo results.


Thiopeptin, a new feed-additive antibiotic: biological studies and field trials. Thiopeptin is a new antibiotic, produced by Streptomyces tateyamensis and developed solely for animal use as a feed additive. The antibiotic content in animal tissue and feed was assayed in terms of the antimicrobial activity against Mycoplasma laidlawii A. This antibiotic was found to be relatively nontoxic in rats and mice. In chickens, this antibiotic is excreted into feces within 48 hr of administration and is not absorbed in tissue. It is well tolerated in both broilers and swine and is highly stable in animal feed. Thiopeptin-supplemented feed contributes to the improvement of weight gain, feed efficiency in chickens and swine, and the egg performance in layers. Thus, thiopeptin, when used as a feed additive, is quite suitable for supplementing animal nutrition.


Social and psychiatric aspects of impotence and premature ejaculation.


Comparative clinical pharmacology of amoxicillin and ampicillin administered orally. Ampicillin and amoxicillin (alpha-amino-p-hydroxybenzyl penicillin) were administered orally in 500-mg doses to eight fasting volunteers in a comparative study in which pharmacokinetic techniques were used. The absorption of amoxicillin was significantly better, as demonstrated by a higher mean peak serum concentration of 7.6 mug/ml as compared to 3.2 mug/ml for ampicillin, an average "area under the curve" that was approximately double that of ampicillin, and an 8-hr urinary recovery for amoxicillin of 60% as compared to 34% for ampicillin. Serum half-lives were the same for the two antibiotics, with values of 60.3 (+/-3.3) min for ampicillin and 61.3 (+/-5.6) min for amoxicillin. The latter drug gave measurable concentrations in the blood at 8 hr in all of eight volunteers, as compared to only three of eight with ampicillin.


Influence of sexual hormones on the differentiation of neural centers.


The role of masturbation in the treatment of orgasmic dysfunction.


Isolation of Thogoto virus from Rhipicephalus bursa ticks in western Sicily.


Nerves in the exchange area of the avian lung.


Effect of dietary iron on iron absorption in man.


Amino acid metabolism in plants. 3. Purification and some properties of a multispecific aminotransferase isolated from bushbean seedlings (Phaseolus vulgaris L.).


Psychiatric manifestation in pellagra.

Psychiatric manifestation in pellagra.


Obstetrical caudal anesthesia in a community hospital: a satisfactory plan.


Cariostatic effect of glycerophosphate.

Cariostatic effect of glycerophosphate.


The inhibitory effect of two slightly soluble compounds on rat caries.


The effect of acetohydroxamic acid on interdental pH assessed with radio telemetry.


Fluoride level in surface enamel after application of fluoride gels.


Evaluation of rat molar fissure caries, a comparison of two examiners.


Increase of inflammatory cell infiltration in rat gingivae with age.


Synergisms and antagonisms of two bacterial strains superinfected in conventional Osborne-Mendel rats.


Gingival inflammation and plaque accumulation by well-adapted supragingival and subgingival proximal restorations.


Pathophysiology of Heart Failure in Congenital Heart Disease.


Mother-attachment and stranger-reactions in the third year of life.


Relationship Between Coronary Thrombosis and Myocardial Infarction.


Colour scintiscans in the diagnosis of hepatic tumors in children.


Lipolytic activity in human intestinal mucosa.


Renal scintiscanning with 99mTc-iron ascorbate in children.


Analysis of urinary 17-ketosteroids and oestrogens by gas-liquid chromatography, as confirmation of anthropometric studies on the neuter threshold age in childhood.


Surgical treatment of paraplegia.

Surgical treatment of paraplegia.


Normal and superinfection in burns: ecology and therapeutic deductions.


The organisation and running of the Burns Unit of Turin.


Silver nitrate in the dressing of extensive burns.


Adaptation-level theory and context effects on sensory judgments: perception for response?


Extensive burns units: the problems of the isolation of the patient.


The use of mefenide in the local treatment of burns.


Object perception in infants.

Object perception in infants.


A cyclic decision model of perceptual alternation.


Visually preadapted constituents of manipulatory action.


Special problems in the burn treatment of children with special reference to the use of a new dressing.


Neurological findings associated with spatial disorders in children.


Search time as a function of context letter frequency.


Contrast sensitivity and increment threshold.


Stimulus pairing in sequential phi motion.


Kinaesthetic spatial aftereffects from one and two wrists: a problem for neural enhancement theory.


Optical scanning in the lateral eyes of the copepod Copilia.


Perceptual indices of performance: the measurement of 'inspection time' and 'noise' in the visual system.


The effects of shock-induced anxiety on noise in the visual system.


The site of orientational constancy.

The site of orientational constancy.


The Schrödinger equation in binocular brightness combination.


Two empirical tests of informal predictions from Helson's adaptation-level theory.


Electrophysiological and psychophysical responses to modulation of contrast of a grating pattern.


Studies on induced motion in the third dimension.


A new apparatus for visual data sampling.


The basic science of the art of line drawing.


'Interest' and 'pleasure': two determinants of a monkey's visual preferences.


Pictorial recognition in a remote Ethiopian population.


Directional asymmetry in the duration of simple movement aftereffects produced by movement aftereffects contingent on colour.


Salt taste sensitivity: a signal detection approach.


Hearing: individual differences in perceiving.


Interocular transfer in normal humans, and those who lack stereopsis.


Phenomenal rarefaction and visual acuity under 'illusory' conditions.


Workable volume and flow concepts of bio-segments by electrical impedance plethysmography.


A flow-chamber for concentration-step experiments with epithelial membranes.


Evoked cortical responses to dichoptically presented patterned light flashes: interocular interaction.


Heterogeneity of memory components of the skilled escape reaction in the rat.


Proteins and glycoproteins of human myelin and glial cell membrane with special reference to myelin formation.


Determination of potential of brain tissue using compound powder electrodes.


A new automated determination of uric acid.


Semiautomatic method for the separation and determination of total triiodothyronine and thyroxine in serum.


Natural proteinase inhibitors distribution, specificity, mode of action, and physiological significance.


Proceedings: Normal and pathological factors which affect tryptophan metabolism in man.


Alteration of red cell membrane subunit pattern after pronase treatment.


Recommendations of the German Society for Clinical Chemistry. Standardisation of methods for the estimation of enzyme activities in biological fluids. Experimental basis for the optimized standard conditions.


Relationship between human and animal infections with A2 /Hong Kong/68 - like strains of influenza virus.


Histologic and electron microscopic study of neuroaxonal spheroid-like structures in experimental myelopathy produced by venous stasis.


Incidence of syphilis in Bangkok, Thailand.


The deoxygenation kinetics of hemoglobin partially saturated with carbon monoxide. Effect of 2,3-diphosphoglycerate.


Purification and some properties of citrate synthase from Penicillium spiculisporum.


DNP derivatives of lysozyme obtained by pH 7.2--effect of modification on physico-chemical properties of the enzyme.


Life support requirements of astronauts. Part 2. Development of stored food and water systems.


Life support requirements astronauts. Part 2. Bioregeneration of food.


Life support requirements of astronauts. Part 2. Chemically regenerated foods.


Clinical significance of juxtaglomerular cell changes in kidney disease.


Prevention of hepatitis in haemodialysis units.


Guidelines for the conservative treatment of chronic uraemia.


Some observations on renal tubular acidosis secondary to interstitial or malformative kidney disease. Effects of treatment with NaHCO3.


Long-term prognosis in acute renal failure of primarily tubular origin.


CCreat and cIn in relation to urine flow in non-uremic subjects.


Remarks on "Microangiopatia diabetica".

Remarks on "Microangiopatia diabetica".


A toxicological study of extractum hippocastani semen (EHS).


The early surgical treatment of burns.

The early surgical treatment of burns.


Report on the work carried out by the "Fede Valletta" Diagnosis and Early Treatment Centre and the Surgical Divison of the Department of Oncology, University of Turin, since their foundation in 1961.


The pre-surgical treatment of the burned surfaces.


Chemoprophylaxis of infection in burns with sulfamylon acetate.


Neglected severe burns.

Neglected severe burns.


Surgical treatment of the late unhealed burn.


Results with screening methods in an investigation of aminoacid metabolism disturbances and urinary excretion of beta-phenylethylamines.


Virus infections and endocrine diseases.


Influenza: notes on its aetio-epidemiology and prevention.


The diaphragm in dystrophia myotonica (an electromiography study).


Reproductive biology in an overcrowded world.


The hallucinations and mortality following bereavement.


Distribution patterns of cortical flash-evoked discharges in darkness and during steady light.


Genetics and disease.

Genetics and disease.


Why are some people anaemic and does it matter?


Alternatives to drug abuse: an analysis.


Registering the addict: recent experiences in the United Kingdom.


Staccato Syndrome as a consequence of drug abuse.


Experiences, problems and perspectives re data collection on drug abusers.


Registering addicts and dangerous drugs in Scandinavia.


The role of the physician in reinforcing and inhibiting drug abuse.


Drug advertising and drug abuse.

Drug advertising and drug abuse.


The role of the pharmaceutical industry in reinforcing and inhibiting the use and misuse of drugs.


The good, bad and potential role of the American pharmaceutical industry in the problem of drug abuse.


The role of the pharmaceutical industry in the production of dangerous drugs. The aspects of the Ministry of Health Israel.


We are all guilty.

We are all guilty.


The necessity of drug analysis for physicians, scientists and educators.


Urine testing for the presence of drugs in the treatment of drug dependent persons with special reference to inpatient treatment.


Testing for drug use: why, when, and what for.


Community intervention in drug abuse.

Community intervention in drug abuse.


Chemical mutagenesis and drugs of abuse in man - a current view of the problem.


Induced chromosome abnormalities in man: their detection and significance.


LSD and chromosomes.

LSD and chromosomes.


Effects of 2,5-dimethoxy-4-methylamphetamine on the behavior of rats in competition for food.


Relative value of various etiological factors in short lasting, adverse psychological reactions to cannabis smoking.


Drug abusers, addicts and their treatment in reference to a structural theory.


Psychiatric models of treatment for drug abuse.


Demonstration of the socializing effect upon methadone maintenance patients in a move from hospital setting to a brownstone (private dwelling). A contribution to the psychodynamics of the setting and relationships to the Methadone Maintenance treatment program.


Family therapy and drug abuse.

Family therapy and drug abuse.


Group therapy in the treatment of the juvenile narcotic addict.


Drug dependence and non-medical use--a question of terminology?


Heroin maintenance?

Heroin maintenance?


Medicine, methadone and morality.

Medicine, methadone and morality.


Critique of theories of methadone use.

Critique of theories of methadone use.


Methadone treatment in opiate addiction.


Methadone, structure and responsibility: a model treatment program for methadone maintenance rehabilitation.


An approach to adolescent heroin abusers: long-term detoxification plus.


Polyphosphate and trimetaphosphate formation under potentially prebiotic conditions.


Empirical support for a stochastic model of evolution.


Studies in prebiotic synthesis: VII. Solid-state synthesis of purine nucleosides.


The calcitonins: an example of unusual evolution.


The possible conservation of genetic information in repetitious sequences of DNA.


Formation of urea and guanidine by irradiation of ammonium cyanide.


Recently published protein sequences. I.


Population size and rate of evolution.

Population size and rate of evolution.


Variation in protein structure and function: primate hemoglobins.


Non-enzymic beta-decarboxylation of aspartic acid.


Non-randomness of base replacement in point mutation.


A note on the hypothesis: protein polymorphism as a phase of molecular evolution.


An applied bioengineering curriculum.

An applied bioengineering curriculum.


Medical engineering technology at the University of New Mexico.


Biomedical engineering at the Indian Institute of Technology (Madras)-I.


A review of second-order effects on Poiseuille's equation for application to blood and other viscous fluids.


Editorial: Undergraduate education for Medical Engineering.


The biomedical engineer in the medical center.


A new approach to Engineering education- the WPI plan.


Food consumption and level of economic development in individual regions of Yugoslavia in 1968.


Ultrastructure of mycoplasma responsible for Corn stunt cultivated in liquid medium.


Editorial: A message from Wesley W. Hall, M.D.


Studies of the probable sites and nature of calcium malabsorption in uremic patients and those undergoing hemodialysis.


Body composition during hemodialysis with high and low bath calcium.


Conditioning and training of the competitive athlete.


Factors influencing hematocrit response to testosterone in patients on chronic hemodialysis.


Androgen therapy in hemodialysis patients.


Knee pain and loping gait in an eleven-year-old girl.


Factors influencing hemoglobin response to testosterone in patients on chronic dialysis.


The legal responsibilities of the team physician.


Improving communications between team physician and radiologist.


Considerations of the middle molecule hypothesis.


Influence on pre-dialysis concentrations of varying the number of dialyses per week keeping total dialysis time per week constant.


Residual renal function and chronic hemodialysis therapy.


The loose-jointed young athlete: recognition and treatment.


Dialysis-induced change of extracellular fluid volume in man.


The middle molecule in present day hemodialysis.


Factors affecting performance in 150 home dialysis patients.


Serum phosphorus control in dialysis patients with aluminum hydroxide gel-containing cookies.


Respiratory gas exchange during hemodialysis.


Evaluation of a new disposable dialyzer (Gambro).


Arthrography of the knee for diagnosis of torn meniscus.


A color atlas of arthroscopy.

A color atlas of arthroscopy.


The expanding frontiers of sports medicine.


Comparison of the EX03 dialyzer cartridge and the high performance ultra-flo II (UFII) coil dialyzer with the Gambro-Lundia plate dialyzer (GL).


Knee injuries. Part I: the torn meniscus.


Experience with a new plate type dialyzer.


Current status of the clinical application of the Redy R dialysate delivery system.


Acute renal failure and pulmonary hemorrhage: recovery after prolonged hemodialysis.


Reconstruction of the extensor mechanism for subluxating patella.


Vessel stenosis as a major cause of A-V shunt failure.


Chronic hemodialysis and dental disease.


Spontaneous arterial occlusion of A-V fistulae during chronic hemodialysis.


Creation of an arteriovenous fistula utilizing a modified bovine artery graft: clinical experience in fourteen patients.


Chemi- and bioluminescence.

Chemi- and bioluminescence.


Rheological study of photo-oxidized contractile proteins.


Singlet oxygen as oxidizing intermediate and photodynamic action.


Remarks on some biological and evolutionary problems of photoreactivation and dark repair.


Action spectra and their interpretation.


Root-like hyphal structures in aspergillar otomycosis.


Effect of age on cardiac metabolism.

Effect of age on cardiac metabolism.


Effect of palmitate on hypoxic myocardial metabolism and contractility.


Metabolism of exogenous and endogenous fatty acids in heart muscle.


Catecholamines and myocardial infarction.


Influence of free fatty acids on myocardial mechanics and oxygen consumption in rat papillary muscles and perfused hearts, under oxygenated and hypoxic conditions.


Inhibition of energy transfer in ischemic heart muscle.


Incorporation of amino acid into total and contractile protein of tissue slices of the hypertrophying rat heart.


Hemodynamics of the hereditary cardiomyopathy of Syrian hamsters.


A biochemical defect in the function of the sarcoplasmic reticulum in the hereditary cardiopathy of the Syrian hamster.


Study of the hypothalamic-hypophyseal system in hereditary cardiomyopathic hamsters.


Abnormal oxidative phosphorylation in skeletal muscle mitochondria of the BIO 14.6 dystrophic Syrian hamster.


Relationship of atrial catecholamines to cytochemistry and fine structure of atrial specific granules.


Cardiac preservation: A morphologic study.


Experimental myocarditis: An autoimmune disease.


Ultrastructural studies on myocardial fibrin deposition in experimental hypertension.


Ultrastructural myocardial changes following experimental narrowing of the coronary arteries.


Studies on the mechanism of increased myocardial resistance.


Significance of morphological changes at the periphery of an experimental myocardial infarct.


Metabolic changes in infarcted and non-infarcted myocardium during the postinfarction period.


Influence of mechanical assisting systems on the acute failing heart.


Pathophysiologic changes in arteriosclerotic and nonarteriosclerotic rats, following isoproterenol-induced myocardial infarction.


Influence of assisted circulation on cardiac metabolism.


Histochemical and electron microscopic studies of norepinephrine-induced myocardial necrosis in rats.


Why "myocardiology?".

Why "myocardiology?".


Ultrastructural studies of various forms of experimentally induced cardiac necroses.


Healing of myocardial necrosis caused by sympathomimetic amines.


Observations on naturally occurring myocardial fibrosis and necrosis in dogs.


Role of the autonomic nervous system in digitalis intoxication.


Acute hyperkalemic cardiomyopathy in the dog.


Cardiotoxicity of brominated vegetable oils.


The pathogenesis of myocardial cell death.


Mechanism of ethanol-induced triglyceride accumulation in the rabbit heart.


Influence of spironolactone and other steroids on the plasma level of digitoxin.


Myocardial loss of functional magnesium. II. In cardiomyopathies of diverse etiology.


Calcium in experimental myocardial ischemia.


Myocardial ion and lipid changes during ischemia and catecholamine induced necrosis: Relation to regional blood flow.


Myocardial potassium loss during ischemia.


Exercise and serum potassium flux: Myocardial metabolic implications.


Prevention of experimental myocardial necrosis by electrolyte solutions.


Stress, hormones, and cardiovascular disease.


The hormonal restoration of the intrinsic contractile function of the atrophic hearts of hypophysectomized rats.


Cardiotoxic effects of emotional, socioeconomic, and environmental stresses.


Physical activity, catecholamines, and platelet stickiness.


Pathogenic significance of disproportion between myocardial oxygen supply and consumption.


Effect of physical training on the exercise electrocardiogram.


Cardioprotective exercise programs in the United States and Canada.


Heart under unusual conditions: Effects of gravitation and chronic hypoxia.


Cardiotoxicity of isoproterenol in experimental animals. Influence of stress, obesity, and repeated dosing.


Energy state and ultrastructure of the substrate-depleted heart.


Myocardial metabolism in experimental cardiogenic shock.


Exercise stress testing in the evaluation of the cardiac patient.


Exercise stress testing in clinical practice.


The physiology of the cerebral circulation.


Editorial: "Hospital engineers--licensed for what?".


Comparative effects of mammalian growth hormone on three spices of Anuran amphibia before metamorphosis.


Studies on the purification of factor VIII.


Leucocyte migration inhibition in horses immunized with detoxified scorpion venom.


Thermodynamics of the binding of S protein to agarose--S peptide to form agarose-ribonuclease S'.


A simplified procedure for the isolation of the sucrase-isomaltase complex from rabbit intestine. Its amino-acid and sugar composition.


[Luteal suppression with D-norgestrel as a method of oral contraception. A report of practical experience (author's transl)].


[Times of appearance and levels of anti-seminal plasma antibodies in rabbits treated with human seminal plasma and spermatozoa (author's transl)].


A proton magnetic resonance kinetic approach to the stereochemistry of carbohydrate enzymic hydrolysis. Hydrolysis of hyaluronic acid by testicular hyaluronidase.


An in-vitro study of the spontaneous motility and rhythmicity gradient in the rat and guinea pig female reproductive tracts.


Analysis of form and speed of flagellar waves according to a sliding filament model.


Assessment.

Assessment.


Digestion and utilization of vegetable proteins in human subjects.


Facilities for the mentally retarded.

Facilities for the mentally retarded.


Induction of low-zone tolerance in germfree sensitized animals.


Letter: The mitochondrial derivative of insect spermatozoa and the diffusion path of ATP.


On the location of myosin in the myxomycete Physarum polycephalum and its possible function in cytoplasmic streaming.


The effect of environmental temperature and nutritional intake on the metabolic response to abdominal surgery.


The elastic properties of stimulated muscle.


Use of gas-liquid chromatography in the analysis of hydrolysates of bovine-oestrus cervical glycoprotein.


Polymerization of tubulin: the linear polymer and its side-by-side aggregates.


A gas chromatographic method for ethanol determination in vapors of biological fluids.


The effect of cycloheximide on the synthesis of major and satellite DNA components in Physarum polycephalum.


Behavioral effects of peer separation, isolation, and reunion on adolescent male rhesus monkeys.


DNA repair after ultraviolet irradiation in synchronous plasmodia of Physarum polycephalum.


Postnatal experience and the detection of the effects of prenatal stress on behavior: a reply to Archer and Blackman.


Mycetoma of upper extremity.

Mycetoma of upper extremity.


Differential interaction of anti-lymphocyte serum with sub-populations of lymph node cells.


Inhibition of rat mammary gland DNA-labelling by actinomycin D and DMBA is neither additive nor synergistic.


Delayed hypersensitivity, macrophage migration, and antibodies in guinea-pigs immunized with diphtheria toxoid. II. Macrophage cytophilic antibody to diphtheria toxoid in desensitized animals.


The identification of immunoglobulin-releasing cells in human tonsillar tissue.


Anemia of chronic renal failure: studies of marrow regulation in the uremic sheep.


Cestodes from rodents in the Republic of South Africa.


Effect of natural teratogens in poisonous plants on fetal development in domestic animals.


The teratogenic effect of cosmetic constituents on the chick embryo.


Development of the chick embryo limb buds after treatment with nitrogen mustard, X-ray irradiation, or in vitro culture.


The effect and mode of action of tetracycline on bone development in vitro.


The effect of organic mercury on intrauterine life.


Drug testing for teratogenicity: its implications, limitations and application to man. Because many of the machanisms of teratogenesis in mammals are unknown and because of the resulting necessity for empirically derived screening protocols, the quality and reliability of teratogenicity investigations vary widely.  Animal screening tests have been introduced, adopted and modified in an attempt to protect the public.  Because of general concern about the effectiveness of testing precedures in predicting the teratogenicity of a drug, almost all new drugs carry a warning that the drug may not be used safely during pregnancy.


Fetal membrane adhesions and congenital malformations.


Observations on effects of analgetic drugs on mother and fetus: comparison between systemic and local drug application during labor.


Drug usage and fetal development: preliminary evaluations of a prospective investigation.


Phospholipase A and its zymogen from porcine pancreas.


Deep freezing of ram semen.

Deep freezing of ram semen.


Effect of urea and wood shavings on populations of soil microfungi, especially Trichoderma species.


Latency between intravenous injection of progestins and the appearance of estrous behavior in estrogen-treated ovariectomized rats.


Neonatal organization of aggression in mice: correlation of critical period with uptake of hormone.


Mice: postpartum aggression elicited by the presence of an intruder.


The dose-response to testosterone propionate of preputial glands, pheromones and aggression in mice.


Activation and inhibition of isolation induced inter-male fighting behavior in castrate male CD-1 mice treated with steroidal hormones.


Differential antagonism, by MER-25, of behavioral and morphological effects of estradiol benzoate in rats.


Masculinization of the female golden hamster by neonatal treatment with androgen or estrogen.


Coital behavior in dogs. XI. Effects of androgenic stimulation during development on masculine mating responses in females.


Pup-killing produced by the administration of testosterone propionate to adult female mice.


Preejaculatory stimulation does not induce luteal activity in the mouse Mus musculus.


Hypothyroidism: learning deficit induced in rats by early exposure to thiouracil.


The effect of varying amounts of exogenous estradiol benzoate on estrous behavior in the rat.


Male rat of odor preferences for female urine as a function of sexual experience, urine age, and urine source.


Circadian and estrual rhythms in food intake in the rat.


Postcopulatory sexual receptivity in the female hamster: the role of the ovary and adrenal.


Gonadal influence on agonistic behavior in the male domestic rat.


The relationships among testosterone, conditioned aggression, and dominance in male pigeons.


Secondary mutations at the B beta incompatibility locus and nuclear migration in the basidiomycete Schizophyllum commune.


Biological techniques for studying the allergenic components of nematodes. I. Detection of allergenic components in Ascaris suum extracts.


Physiological variations in serum triglycerides.


The effect of host age on the course of infection of Raillietina cesticillus (Moin, 1858) in the fowl.


Studies on the course of infection of the poultry cestode Raillietina cesticillus (Molin, 1858) in the definitive host.


A rapid technique for the concentration and collection of helminth eggs from large quantities of faeces.


Recurrent familial psychosis of the schizo-affective type.


Study of protein-protein and of protein-ligand interactions by potentiometric methods.


Measurement of histidine residue titration by NMR spectroscopy.


In vitro studies on a breathalyzer.

In vitro studies on a breathalyzer.


Psychopharmaceutical restoration to present sanity (mental competency to stand trial).


The action of hydroxylamine on myosin.

The action of hydroxylamine on myosin.


Studies on 5-hydroxyuridine (isobarbituridine): VII. Yeast nucleotide pool analysis.


On the nature of the mechanism of oxidative phosphorylation in mitochondria: a model and supportive evidence.


Studies on 5-hydroxyuridine (isobarbituridine): VIII. Instability in partition chromatography solvent ethylacetate-1-butanol-ligroin-water.


Influence of different media and bloods on results of diffusion antibiotic susceptibility tests. As part of an International Collaborative Study, the influence of medium and certain medium components on the results of disc susceptibility testing with nine antibiotics was examined and statistically evaluated. Four basic media, Trypticase Soy Agar, Grove and Randall's formula # 9 agar, and Mueller-Hinton agar with and without 1 mg of l-tryptophan per 100 ml, were used with six bacterial strains. Significant differences in zone diameters occurred with most antibiotics. The largest consistent differences were seen with tetracycline, and appeared to result from varying degrees of chelation of the antibiotic with free cations in the media. Reproducibility studies on different batches of Mueller-Hinton agar from two manufacturers showed some statistically significant differences, which were small except with tetracycline. Reproducibility between the products of a single manufacturer was excellent. The results of experiments to determine the effect of the addition of 5% blood of different species to agar medium showed that medium containing citrated or defibrinated horse, rabbit, sheep, or human blood yielded closely similar zone diameters, except that tetracycline zones were larger with citrated blood. A single type of medium should be selected for routine susceptibility tests whenever possible, and reproducibility of performance of the products of different manufacturers should be sought.


Radioimmunoassay for plasma testosterone.


Dipeptide frequencies in proteins and the CpG deficiency in vertebrate DNA.


Etiologic factors in ischemic heart disease: The elusive role of emotional stress.


Modification of cellular lipid metabolism by psychological stress.


Contribution of certain nutrients added to foods to dietary intake.


Studies in heterophile antibodies. A survey of levels in local normal adults.


Seasonal sexual behavior: intrauterine contraceptive devices in a confined troop of Japanese macaques.


Multiple chromosome aberrations in a lymphosarcomatous tumor.


The effects of Fasciola hepatica on Lymnaea truncatula.


Role of plasmalogen in heart diseases.

Role of plasmalogen in heart diseases.


Distribution and metabolism of disodium cromoglycate in rats.


Statistical analysis of dynamic tracer data.


Interactive computer strategies for living nervous system research.


A computer analysis of EEG spectral signatures from normal and dyslexic children.


Quantification of hand tremor in the clinical neurological examination.


An implantable blood pressure and flow transmitter.


An arrhythmia--anomalous beat monitoring system.


The specific resistance of canine blood at body temperature.


Semiautomatic quantification of sharpness of EEG phenomena.


Automated calibration of blood pressure signal conditioners.


An automatic DC-level compensation circuit for electrophysiology.


A hybrid broad-band EEG frequency analyzer for use in long-term experiments.


Three-electrode probe for catheter-type blood flowmeters.


Further conclusions regarding the infleunce of word meaning on the cortical averaged evoked response in audiology.


Adult auditory evoked vertex potentials in sleep.


Threshold of subjective auditory handicap.


Measurement of the precise cochlear reserve in otosclerosis value of speech Weber test.


Site of lesion testing. An aid in the early diagnosis of cerebro-vascular disease.


Propagated and nonpropagated myometrial contractions in normal menstrual cycles.


Avoidance of dual publication. Statement by the Council of Biology Editors. Norinyl 1+50 oral contraceptive pills contain 1 mg of the progestin, norethindrone, and .05 mg (or 50 mcg) of the estrogen, mestranol. These pills can either be taken in 21-day or 28-day therapy cycles. This dosage is low but effective. Oral  contraception is supposed to prevent pregnancy by suppressing ovulation and by causing changes in the endometrium and cervical mucus. Contraindications are: 1) a history of thrombosis or cerebral disorders, 2) liver dysfunction, 3) suspected  breast cancer, 4) suspected estrogen-dependent neoplasia, and 5) undiagnosed abnormal genital bleeding. Close surveillance of women taking oral contraceptives is recommended. The areas to be closely examined periodically are listed. Adverse  reactions and warning signs are enumerated. A warning is issued of increased risk of the following conditions due to oral contraceptive therapy: 1) thrombotic disorders, 2) neuroocular lesions, and 3) fluid retention and hypertension.


Problems in electric response audiometry (ERA) during sedation.


Role of fibrin in a model of pregnancy toxemia in the rabbit.


Artefact recognition and diazepam in electric response audiometry.


The effect of prostaglandin E 1  on the pregnant human uterus.


Abortifacient efficacy of intravaginal prostaglandin F2 . This study determines the efficacy and incidence of side effects associated with intravaginal prostaglandin F2alpha (PGF2alpha).  20 healthy patients (16 to 30 years of age; 9-16 weeks gestational age) with no history of threatened abortion in the current pregnancy were studied.  Baseline hematologic, metabolic, urinary, and hormonal studies were conducted.  Transabdominal amniocentesis was performed in 7 patients.  The uterus was observed for spontaneous contractility.  Lactose tablets with 50 mg PGF2alpha (THAM salt) were administered vaginally.  The intensity and frequency of uterine contractions in the 7 monitored patients determined the treatment regimen.  Prostaglandin tablets were inserted at hourly intervals to maintain frequency of contractions at 5 per 10 minute time interval and/or intensity of contractions greater than an average of 40 mm Hg over a 10 minute-period.  13 patients whose uterine activity during the abortion process was assessed by clinical observation were given a similar time schedule.  Blood studies were peformed 6 hours after the onset of therapy and immediately following abortion.  Analgesia were used intramuscularly as antiemetic agents where necessary.  Prepared questionnaires and personal interviews were completed at the 4-week clinic visit to determine patient acceptability of the method.  19 of 20 patients aborted, with 7 classified as complete and the remaining 12 requiring a uterine exploration and curettage for removal of retained placental fragments.  Average induction-complete abortion interval was 17 hours and 50 minutes.  There was no difference between multiparous and primiparous patients.  In 1 patient who failed to abort with the prostaglandin tablet, administration of 900 mg PGF2alpha and hypertonic saline were used to facilitate abortion which occurred 24 hours later.  Emesis occurred in 18 patients, diarrhea in 13, and fever in 11.  Of 15 patients who agreed to an interview during the clinic visit, 14 stated they would choose the method again.  Vaginal administration of PGs appears to exert effects by systemic, rather than by local mechanism.  Although this method is effective, it has a high incidence of side effects and is associated with increased utilization of professional time.


An approach to the study of brain damage. The principles of fetal electroencephalography.


Cardiorespiratory responses to pregnancy and exercise in normal women and patients with heart disease.


Placental transfer of methicillin.

Placental transfer of methicillin.


Social hearing handicap index. Social handicap in relation to hearing impairment.


Racial differences in maternal smoking effects on the newborn infant.


Tensile strength of the umbilical cord.

Tensile strength of the umbilical cord.


Bladder dysfunction following Schauta hysterectomy.


The role of sedation in ERA from the vertex.


Effects of verbal association on averaged auditory evoked response.


Routine use of electrocochleography (cochlear audiometry) on human subjects.


Relationship of hypermagnesemia and hyperkalemia to muscle Mg and K in acute and chronic azotemia in the rat.


Oxymetholone: differentiation between the ovarian and endometrial effects.


Synthesis of glucose in human thrombocytes.


Mechanism of chlorpropamide-induced antidiuresis in man: evidence for release of ADH and enhancement of peripheral action.


Effect of glucagon and glucose load on glucose kinetics, plasma FFA, and insulin in dogs treated with methylprednisolone.


Transport of alpha-methyl-D-glucoside by human kidney cortex.


Hepatic acetate levels in relation to altered lipid metabolism.


Biological effects of anthramycin methyl ether. 3. Inhibition of erythropoiesis.


Effectiveness of antitumor agents administered subcutaneously to L1210 leukemic mice in silicone rubber devices.


Ethambutol in therapy of complicated tuberculosis.


Antibiotic treatment with pivampicillin chloride in respiratory and urinary tract infections.


The VATER association. Vertebral defects, Anal atresia, T-E fistula with esophageal atresia, Radial and Renal dysplasia: a spectrum of associated defects.


Ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome. Its association with conductive hearing loss.


Treatment of acrodermatitis enteropathica by intravenous amino acid hydrolysate.


The prevalence of bacteriuria in full-term and premature newborn infants.


Thromboembolus to abdominal aorta in a neonate.


Metrication and infant formulas.

Metrication and infant formulas.


Polymorphonuclear lobe counts in congenital hypothyroidism.


Avoidance of undesirable effects of blue light in phototherapy.


Hemoglobin S-D disease in a Negro child.


Incidence of bacteriuria in the nephrotic syndrome in children.


Endotracheal tube position in infants.

Endotracheal tube position in infants.


Depletion of iron-containing enzymes in iron deficiency anemia.


Pathogenesis of Leigh's encephalomyelopathy.


Treatment of streptococcal pharyngitis.

Treatment of streptococcal pharyngitis.


Resistance to exogenous human growth hormone in psychosocial short stature (emotional deprivation).


Attenuated form of Wiskott-Aldrich syndrome.


Sodium bicarbonate therapy for respiratory distress syndrome.


Metastasizing fetal neuroblastoma with involvement of the placenta simulating fetal erythroblastosis. Report of two cases.


Propranolol in the treatment of cardiac arrhythmias associated with amitriptyline intoxication.


Controlled trial comparing agar, intermittent phototherapy, and continuous phototherapy for reducing neonatal hyperbilirubinemia.


Serum alkaline phosphatase in infants with obstructive jaundice: relation to vitamin D supplementation.


Late death from neuroblastoma.

Late death from neuroblastoma.


Psychophysiologic effects in the neonate of prone versus supine placement.


Hydrops fetalis in association with chorioangioma of the placenta.


Hypoglycemia in infants of diabetic mothers: effect of epinephrine therapy.


Temporal patterns of circulating hormones as assessed by continuous blood sampling.


Growth hormone secretion in congenital adrenal hyperplasia.


Corpus luteum-inhibiting action of oxymetholone.


A rapid method for the measurement of androgen kinetics and conversion to estrogens using Sephadex LH-20 column chromatography.


Comparative fate of estrone and estrone sulfate in man.


Mechanism of chlorpropamide action in patients with diabetes insipidus.


Chromatographic pattern of human intestinal glucagon-like immunoreactivity (GLI).


Evidence for "big" and "little" components of human plasma and pituitary growth hormone.


A simplified radioimmunoassay for triiodothyronine.


Human ovarian enzymes during pregnancy.

Human ovarian enzymes during pregnancy.


Stimulation of thyrocalcitonin secretion by pentagastrin and calcium in 2 patients with medullary carcinoma of the thyroid.


The use of L-DOPA in the diagnosis of hyposomatotropism in children.


Absence of intrinsic biological activity in LH and hCG subunits.


Studies of endocrine function in "isolated" gonadotropin deficiency.


Cutaneous effects of cold exposure.

Cutaneous effects of cold exposure.


A differential effect of ethinyl estradiol upon plasma FSH and LH relating to time of administration in the menstrual cycle.


Appointment with death. Attitudes and communications.


Gastrocolic fistula secondary to benign gastric ulcer.


Radiologic problem case: colonic diverticulosis.


Levels of anxiety in colonic disorders.

Levels of anxiety in colonic disorders.


Ornithine transcarbamylase deficiency: a cause of lethal neonatal hyperammonemia in males.


Increased prevalence of cholelithiasis in men ingesting a serum-cholesterol-lowering diet.


Frequency of sickling disorders in U.S. blacks.


Cholangiographic manifestations of acute biliary colic.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 1-1973.


A double standard for psychosomatic papers?


Can a cholesterol-lowering diet cause gallstones?


Two deaths from mid-trimester abortion.

Two deaths from mid-trimester abortion.


A simple screening procedure for hemoglobin S.


Fiberoptic bronchoscopy in acute respiratory failure in the adult.


Morphine for severe asthma?

Morphine for severe asthma?


Marine training.

Marine training.


Paroxysmal supraventricular tachycardia.


Marihuana not for skiers.

Marihuana not for skiers.


Surgical management of granulomatous colitis.


Tranexamic acid in hereditary angioneurotic edema--a progress report.


Glucagon and obesity.

Glucagon and obesity.


Maintenance of "very good health".

Maintenance of "very good health".


Cryobanking of semen.

Cryobanking of semen.


Operating costs of "blue" plans.

Operating costs of "blue" plans.


Evidence for x-linked dominant inheritance of ornithine transcarbamylase deficiency.


Oxytocin receptors: oxytocin analogs, but not prostaglandins, complete with 3H-oxytocin for uptake by rat uterus.


Ovulation in postpartum rats.

Ovulation in postpartum rats.


Estrone interaction with the rat uterus: in vitro response and nuclear uptake.


Effect of repeated replenishment of hypothalamic extract on LH and FSH secretion in monolayer cultures of rat anterior pituitary cells.


Evidence that the goitrogen, methimazole, interferes with the extrathyroidal utilization of exogenous thyroxine.


FSH induction of sensitivity to LH: one cause of sexual maturation in the male rat.


Mechanism of inactivation of vasopressin and oxytocin by the isolated perfused rat kidney.


Thyrotropin secretion and metabolism in rats during propylthiouracil treatment.


The effects of growth hormone on DNA polymerase activity in the liver of normal and hypophysectomized rats.


Effect of the sudden withdrawal or increase of suckling on serum LH levels in ovariectomized postparturient rats.


Effect of hypothalamic lesions and androgen on plasma LH levels in castrated male gerbils.


Bovine proparathyroid hormone: structural analysis of radioactive peptides formed by limited cleavage.


Biological activities of 7alpha-hydroxylated C19-steroids and changes in rat testicular 7alpha-hydroxylase activity with gonadal status.


Thyromimetic activity of methylene-bridged thyroid hormone analgos.


Hypothalamic catecholamine effects on plasma levels of prolactin and growth hormone in sheep.


Autoradiographic localization of radioactivity in the rat brain after the injection of 1,2-3H-testosterone.


Kinetics of immunoreactive insulin in obese hyperglycemic laboratory rodents.


Characterization of a cytoplasmic receptor for 5alpha-dihydrotestosterone in the caput epididymidis of intact rabbits.


Comparison of specific 17beta-estradiol-receptor interactions in the anterior pituitary of male and female rats.


Glucose intolerance and impaired secretion by prostaglandin A1 in fasting anesthetized dogs.


Relationship of phenformin-induced hyperinsulinism to its effect on circulating glucose levels in the rat.


Diphenylhydantoin inhibition of calcitonin secretion in the pig.


The biliary excretion of thyroxine and glucuronic acid conjugate in normal and Gunn rats.


Effects of endogenous parathyroid hormone on calcium, magnesium and phosphate metabolism in rats.


Pituitary and serum FSH and LH levels after massive and selective depletion of the germinal epithelium in the rat testis.


Production and physiologic effects of progesterone metabolites in pregnant and pseudopregnant rats.


Steroid hormone uptake by anterior pituitary cell suspensions.


Identification of central trigeminal nociceptors and the effects of nitrous oxide.


The spinal cord dorsal horn.

The spinal cord dorsal horn.


Effects of halothane anesthesia on functional residual capacity and alveolar-arterial oxygen tension difference.


Mechanisms of general anesthesia: failure of pentobarbital and halothane to depolymerize microtubules in mouse optic nerve.


Renal responses to "light" methoxyflurane anesthesia.


Fluorometabolites of methoxyflurane: serum concentrations and renal clearances.


Lamina-specific suppression of dorsal-horn unit activity by detamine hydrochloride.


Hemodynamic effects of morphine and morphine-nitrous oxide in valvular heart disease and coronary-artery disease.


Effects of respiratory alkalosis on oxygen consumption and oxygenation.


Effects of mechanical ventilation, muscle paralysis, and posture on ventilation-perfusion relationships in anesthetized man.


Solubility of nitrous oxide in water, 20-80 C.


Pin-indexing failures.

Pin-indexing failures.


A monitoring system incorporating ultrasonic fetal cardiotachometry and uterine electromyography.


Bilateral tension pneumothorax following induction of anesthesia in two patients with chronic obstructive airway disease.


Anesthetic hazards of cold urticaria.

Anesthetic hazards of cold urticaria.


Acute water intoxication during transurethral resection of the prostate, using glycine solution for irrigation.


Audio-reflexometry in testing hearing of very young children.


Some physiologic aspects of the averaged vertex response in humans.


Automatic versus standard audiometry.

Automatic versus standard audiometry.


The difference limen for intensity as an indicator for adaptation and fatigue in auditory function.


Objective measurements of speech level.

Objective measurements of speech level.


The coronary-care unit: necessity or luxury?


The BMJ at home and abroad.

The BMJ at home and abroad.


Effect of funnel chest on cardiac function.


Pacemaker placement.

Pacemaker placement.


Mediocre effects of reserpine on tardive dyskinesia.


Hyperthyroidism without calluses.

Hyperthyroidism without calluses.


Hypocholesterolemia in idiopathic hirsutism.


Indications for induction of labor.

Indications for induction of labor.


Familial thymic aplasia--genetic defect or maternal effect.


Enzymatic assay for gentamicin.

Enzymatic assay for gentamicin.


Properdin--its biologic importance.

Properdin--its biologic importance.


Pneumothorax and Horner's syndrome.

Pneumothorax and Horner's syndrome.


Nursing homes and jails.

Nursing homes and jails.


Differences in rates of gastrin release in normal persons and patients with duodenal-ulcer disease.


Development of pulsus paradoxus in the presence of airways obstruction.


Failure of rubella herd immunity during an epidemic.


Notes of a biology-watcher. Death in the open.


End results, cost and productivity of coronary-care units.


Stereopsis without image segregation.

Stereopsis without image segregation.


A study of the effects of bleaching on the width and index of refraction of frog rod outer segments.


Monoptic and dichoptic metacontrast across the vertical meridian.


Electroretinogram of the turtle retina obtained with flickering light.


The opitcal system of the goldfish eye.

The opitcal system of the goldfish eye.


Contrast effects in geometric illusions.


Reaction time as a measure of the temporal response properties of individua colour mechanisms.


A relationship between the detection of size, rate, orientation and direction in the human visual system.


The effects of temperature on the psychophysical and electroretinographic spectral sensitivity of the chromatically-adapted goldfish.


Contrast in night vision.

Contrast in night vision.


Asymmetries related to cerebral dominance in returning the eyes to specified target positions in the dark.


Unconditioned response to light in Limulus: mediation by lateral, median, and ventral eye loci.


The tetrahcromatic colour match as a colorimetric technique.


Atrial dissociation.

Atrial dissociation.


Bacterial endocarditis presenting as complete heart block with paradoxical (left-to-right) pulmonary emboli.


Clinical pathologic conference. Septal defect with anomalous origin of the left coronary artery from the pulmonary trunk.


Temporary repolarization abnormalities during coronary artery visualization.


Ventricular septal defect with aortic insufficiency. Angiocardiographic aspects and a new classification.


Interesting peculiarities of the spatial dynamic architecture of the coronary arteries.


Quinidine and countershock: a reappraisal.


Coronary heart disease: significance of the morphologic lesions.


Percutaneous myocardial and pericardial biopsy with the Menghini needle.


Levocardia with visceral heterotaxy--isolated levocardia: pathologic anatomy and its clinical implications.


A study of hypertension in the inner city. A student hypertension survey.


Influence of volume expansion on proximal tubular sodium reabsorption in congestive heart failure.


Systolic time intervals in constrictive pericarditis and severe primary myocardial disease.


Arvin therapy in experimental pulmonary embolism.


Gap in A-V conduction in man; types I and II.


Techniques of catheterization of the pulmonary veins and pulmonary venous atrium following Mustard's operation.


Serum xanthine oxidase. An experience with 2000 patients.


Influence of antidiuretic hormone on pancreatic exocrine secretion in man.


Factors influencing the healing rate of chronic gastric ulcer.


Postoperative gastric lleus.

Postoperative gastric lleus.


The effect of bile on the gastric secretory responses of vagally denervated canine fundic pouches.


Hepatic failure in a case of mycosis fungoides a case report and review of the literature.


Intestinal perforation during simultaneous lactose tolerance test and motility investigation.


"Just eliminate lactose from your diet and you'll be fine".


Trichobezoar--an unusual cause of megaloblastic anemia and hypoproteinemia in childhood.


Small intestinal absorptive functions in iron deficient rats.


Repeatability of gastric analysis.

Repeatability of gastric analysis.


Nonviral hepatitis in drug addicts.

Nonviral hepatitis in drug addicts.


Clear cell sarcoma of tendons and aponeuroses with melanin.


Focal lipid cardiomyopathy in an infant with paroxysmal atrial tachycardia.


Fluorescence microscopy of amyloid using mixed illumination.


Lymphoid infiltration and amyloidosis of lung in Sjögren's syndrome.


Nonrespiratory bronchiolar deformities. Graphic assessment in normal and emphysematous lungs.


Heterotopic cartilage in the thyroid.

Heterotopic cartilage in the thyroid.


Microarteriographic studies of primary pulmonary hypertension. A quantitative approach in two patients.


Lysosomes in the epithelial component of Warthin's tumor.


Pulmonary veno-occlusive disease associated with pulmonary phlebitis.


Epithelioid sarcoma. An electron microscopic study.


Inheritance of the Dubin-Johnson syndrome.


Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome.


Hyperglucagonism induced by glucocorticoid treatment in man.


Fourth heart sound as a normal finding in older persons.


Lower discharge weight and shortened nursery stay for low-birth-weight infants.


Deep vein thrombosis and pulmonary embolism in congenital factor VII deficiency.


Serum enzymes and electrocardiograms after coronary arteriography.


Glucagon.

Glucagon.


Research on minors, prisoners and the mentally ill.


Australia antigen--transmission in laboratory.


Outbreak of influenza A2.

Outbreak of influenza A2.


Thermographic detection of breast cancer.


Split brain and the spread of carcinoma.


Technetium scan for acoustic neuroma.

Technetium scan for acoustic neuroma.


Intra-arterial secobarbital.

Intra-arterial secobarbital.


Vascular catheters.

Vascular catheters.


Plastic-surgery monopoly?

Plastic-surgery monopoly?


Subprofessional medical librarians.

Subprofessional medical librarians.


The omnivorous chimpanzee.

The omnivorous chimpanzee.


Bronchial deposition and clearance of aerosols.


Clearance of inhaled particles from the human nose.


Inhaled aerosols.

Inhaled aerosols.


Aerosols in nature.

Aerosols in nature.


Production and characterization of aerosols.


Convective patterns of flow during inspiration.


Measurement of pulmonary air spaces using aerosols.


Aerosol effects on smooth muscle and airway visualization technique.


Deposition of aerosols in pulmonary disease.


Peripheral airway obstruction and particulate deposition in the lung.


Folate metabolism and the anticonvulsant efficacy of phenobarbital.


Protective adaptation of brain to water intoxication.


Scapuloperoneal muscular atrophy with cardiopathy. An X-linked recessive trait.


Plasminogen in normal and abnormal human cerebrospinal fluid.


Wyburn-Mason syndrome. Report of two cases without retinal involvement.


Cyclic fluctuation in blood granulocyte DNA labeling: comparison of tritiated thymidine and radiophosphorus.


Successful management of a subdural hematoma in a hemophiliac with an anti-factor VIII antibody.


Lymphocyte plasma membranes: analysis of proteins and glycoproteins by SDS-gel electrophoresis.


Leukocyte labeling with  51 chromium. IV. The kinetics of chronic lymphocytic leukemic lymphocytes.


Studies on the hemoglobins of pinnipeds.


Refractory anemia with dysproteinemia: long-term therapy with low-dose corticosteroids.


Control of erythropoiesis in rats with adjuvant-induced chronic inflammation.


An unusual pattern of neutrophil kinetics in sickle cell anemia.


Increase in circulating stem cells in patients with myelofibrosis.


Humoral stimulators of granulocyte production.


Cyclic neutropenia: the relationship between urine granulocyte colony stimulating activity and neutrophil count.


Chemotherapy of mouse myeloma: quantitative cell cultures predictive of response in vivo.


The question of cycling of the blood neutrophil concentrations and pitfalls in the statistical analysis of sampled data.


Variable transmission rates of a B-chromosome in Myrmeleotettix maculatus (Thumb.) (Acrididae: Orthoptera).


Polytene chromosomes of the tsetse fly Glossina morsitans morsitans.


DNA amounts in the nuclei of Paramecium bursaria.


A Robertsonian translocation in the fresh-water triclad Dugesia lugubris: karyometric analysis and evolutionary inferences.


Homologies of repetitive DNA sequences among Crustacea.


Stable telocentric chromosomes produced by centric fission in Chinese hamster cells in vitro.


Cytogenetics of the parthenogenetic grasshopper Moraba virgo and its bisexual relatives. I. A new species of the virgo group with a unique sex chromosome mechanism.


Fine structure of fast-twitch and slow-twitch guinea pig muscle fibers.


Primary and metastatic medullary thyroid carcinoma. Determination of thyrocalcitonin content by bioassay.


Fibromuscular disease of the segmental renal arteries. Surgical treatment by graduated internal dilatation.


Reverse catheterization of a thrombosed vein.


Postthrombotic venous obstruction in the lower limb.


Pancreatectomy and liver damage.

Pancreatectomy and liver damage.


Selective angiography as a diagnostic aid in acute massive gastrointestinal bleeding.


Axillary-axillary bypass for the "subclavian steal" syndrome.


Rapid tracheal injury by cuffed airways and healing with loss of ciliated epithelium.


Reconstruction of the aortic valve. Correcting valve incompetence due to acute dissecting aneurysm.


Limitations of impedance phlebography for diagnosis of venous thrombosis.


Compression of the deep venous system of the lower leg during inactive recumbency.


Positional factors in venous impedance plethysmography.


Controlling the growth of aortopulmonary anastomoses in piglets.


Immunosuppression in arterial and venous allografts.


Infusion of cell-free fluids into rabbits in hemorrhagic shock. Replacement of blood with crystalloid fluids of various tonicities.


Pylorojejunostomy as an alternative to pyloroplasty.


Upper intestinal microfloral control. Effects of gastric acid and vagal denervation on bacterial concentrations.


Anterior tibial compartment syndrome following muscle hernia repair.


The assay of medical student performance using a 'mini' computer.


Medical student evaluation of teachers and curriculum.


Health record of 92nd Congress is a mixed one.


The National Intern and Resident Matching Program, 1966-72.


What's at stake in health policy.

What's at stake in health policy.


Toward a national health manpower policy.


A tiger by the tail: the governance of the academic health sciences center.


The challenge of health professions education in the seventies.


The continuum of medical education.

The continuum of medical education.


The role of the academic health center in delivering health care.


Directions for research in the academic health center.


AAMC chairman's address.

AAMC chairman's address.


Medical education as a humanizing process.


A prototype for curriculum development in medical education.


Teaching veterinary aspects of public health in a segmented curriculum.


Health at the crossroads: which road to follow.


The medical college admission test as a predictor of grade factors.


A computer program for simulating the patient-physician encounter.


The revolution in birth control practices of U.S. Roman Catholics. There has been a wide and increasing defection of Roman Catholic women from the traditional teaching of their Church on the subject of birth control over the past two decades and a resulting convergence of Catholic and non-Catholic contraceptive practices. By 1970, two-thirds of all Catholic women were using methods disapproved by their Church; this figure reached three-quarters for women under age 30. Considering the fact that most of the one-quarter of young Catholic women conforming to Church teaching had never used any method, the percentage of those deviating may well reach 90 as these women grow older and the problems of fertility control become more important. Much of this increasing deviation has been among the more educated Catholics, who were formerly the most faithful adherents to Church teaching. The change between 1965 and 1970 was especially striking for Catholic women who had attended college. Perhaps the most significant finding is that the defection has been most pronounced among the women who receive Communion at least once a month. Even among this group, the majority now deviates from Church teaching on birth control; among the younger women in this group, the proportion not conforming reaches two-thirds. It seems abundantly clear that U.S. Catholics have rejected the 1968 papal encyclical's statement on birth control and that there exists a wide gulf between the behavior of most Catholic women, on the one hand, and the position of the more conservative clergy and the official stand of the Church itself, on the other. That many Catholics can continue in their other religious practices and simultaneously deviate on the issue of birth control is an interesting commentary on the process of social change. Ultimately this crisis of authority will probably be resolved by a change in official teaching, since it seems doubtful that such a major discrepancy can continue indefinitely without other repercussions. At a minimum, the cost to the Roman Catholic Church will be a loss of authority in a major area of life: that of sex and reproduction.


Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. A peptide has been isolated from ovine hypothalamus which, at 1 x 10(-9)M, inhibits secretion in vitro of immunoreactive rat or human growth hormones and is similarly active in vivo in rats. Its structure is H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH The synthetic replicate is biologically active.