Quantitative lysosomal enzyme activity changes in the neural lobe of the rat following water deprivation and lactation.


Quantum chemical studies on the conformational structure of nucleic acids. IV. Calculation of backbone structure by CNDO method.


Radiation-induced dominant lethality in oocytes of Drosophila hydei, with emphasis on the differential sensitivity of the immature stages in class B.


Quinine fatality--case report.

Quinine fatality--case report.


Rabies.

Rabies.


Radioactivity in North Carolina surface, cistern, and saline waters, 1971.


Radiation-induced mutation rate and DNA content in Schizosaccharomyces pombe.


Quingestanol acetate metabolism in women. The metabolism of quingestanol acetate (QA) was studied in 3 women, and an assessment of the bioavailability of the oral dosage form was made.  QA was absorbed rapidly and showed a high order of bioavailability after oral administration.  The composition of the radioactive steroids in the plasma suggests that the initial biotransformation of the drug involves 2 pathways, the deacylation to quingestanol and O-dealkylation to norethindrone acetate, and that both of these  metabolites are subsequently converted to norethindrone.


Radioactivity in airborne particulates and precipitation.


Radiographic and photoendoscopic studies in posterior urethral valves in enuretic boys.


Race as a variable affecting the treatment involvement of children.


Rabbit liver tRNA nucleotidyltransferase.


Radiochromate-binding capacity of human tonsillar lymphocytes.


Radical surgery combined with radiotherapy in the treatment of cervical carcinoma.


Radiographic investigation of endodontically treated teeth based on two different radiographic projections.


Radioimmunoassay for human parathyroid hormone.


Radiographic ureteral changes with appendicitis.


Radiological case of the month: Congenital anhidrotic ectodermal dysplasia.


Radiologic seminar CXXXVII: the pseudofractures of osteomalacia.


Radioimmunoassay for the detection of the core of the Dane particle and antibody to it.


Radioisotope scintigraphy in osteomyelitis.


Radiological case of the month.

Radiological case of the month.


Radiology case of the month.

Radiology case of the month.


Radiological manifestations in familial dysautonomia.


Radiology of uncomplicated asthma.

Radiology of uncomplicated asthma.


Radionuclide angiography in the diagnosis of carotid cavernous sinus fistula.


Radionuclide imaging in epididymo-orchitis.


Rapid hypertonic glucose infusion: organ location of label after (14C)glucose during hemorrhagic shock.


Rapid evaluation of effect of excipients on color fading. II.


Rapid establishment of ethanol as a reinforcer for rats.


Rapid and selective inhibition of RNA synthesis in yeast by 8-hydroxyquinoline.


Rapid method for the radioisotopic analysis of gaseous end products of anaerobic metabolism. A gas chromatographic procedure for the simultaneous analysis of (14)C-labeled and unlabeled metabolic gases from microbial methanogenic systems is described. H(2), CH(4), and CO(2) were separated within 2.5 min on a Carbosieve B column and were detected by thermal conductivity. Detector effluents were channeled into a gas proportional counter for measurement of radioactivity. This method was more rapid, sensitive, and convenient than gas chromatography-liquid scintillation techniques. The gas chromatography-gas proportional counting procedure was used to characterize the microbial decomposition of organic matter in anaerobic lake sediments and to monitor (14)CH(4) formation from H(2) and (14)CO(2) by Methanosarcina barkeri.


Rapid resolution of coronary arterial emboli. Myocardial infarction and subsequent normal coronary arteriograms.


Rapid diagnosis of infection by gas-liquid chromatography: analysis of sugars in normal and infected cerebrospinal fluid. A highly reproducible procedure was developed for gas-liquid chromatographic analysis of trimethylsilyl derivatives of normal human cerebrospinal fluid. Fourteen normal human cerebrospinal fluid samples tested with this procedure contained alpha- and beta-glucose as well as isomers of two unidentified sugars. Chromatographic changes in three cases of meningeal inflammation (two cryptococcosis and one thalamic astrocytoma) were limited to decreased concentrations of all sugars. In one case of early meningitis, the concentrations of the unknown sugars decreased before glucose. Now that a reproducible chromatogram of the trimethylsilyl derivatives of normal human cerebrospinal fluid has been established, more samples of abnormal cerebrospinal fluid should be prepared by these methods and examined by gas-liquid chromatography. It may be possible to identify unique products of infectious agents which will permit rapid diagnosis of central nervous system infection.


Range-finding toxicity data: list 8.

Range-finding toxicity data: list 8.


Rate of pressure fall in right ventricle during isovolumic relaxation.


Rapid quantitative assay for erythrocyte porphyrins.


Rating scales and their value.

Rating scales and their value.


Rates of cellular and antibody incorporation of 3H-histidine in mice during secondary responses to tetanus toxoid.


Reaction of diethyl pyrocarbonate with nucleophiles.


Reactions of 2-acyloxyisobutyryl halides with nucleosides. V. Reactions with cytidine and its derivatives;.


Reappraisal of levodopa therapy for Parkinson's disease. A three-year experience with outpatients in private practice.


Recent advances in biomedical engineering.


Rearrangement of benzylidenequinuclidinones to tetrahydropyridoindoles. A novel synthesis of indole alkaloids of the eburnamine type.


Radiosterilized tetracycline ophthalmic ointment.


Recent studies of person-person transmission of Hodgkin's disease.


Receptors involved in the action of 5-HT and tryptamine on the isolated rat stomach fundus preparation.


Reciprocal metabolic inhibition of toluene and trichloroethylene in vivo and in vitro.


Reclosure of sternotomy disruption produced by hiccups.


Recognition memory, and head injury.

Recognition memory, and head injury. Severely head injured adults were tested on a recognition memory procedure involving the identification of eight recurring shapes among a series of 160. Compared with a control group, the tested patients showed many fewer correct responses. Their type of error was commonly a failure to recognize rather than a false recognition. The severity of the memory deficit was related to the length of post-traumatic amnesia (PTA), but to neither the presence of neurological signs at the time of memory testing, nor to the time after injury at which the patients were tested. The older patients showed a more significant relationship between PTA and memory score than the younger patients.


Recombination of human erythrocyte apoprotein and lipid. II. Visualization of apoprotein-lipid bilayer complex by freeze-etching.


Recombinational DNA repair and sister chromatid exchanges.


Recommendation for revised emergency exposure limits for spills of NF3.


Reconstitution of grana thylakoids in spinach chloroplasts.


Reconstitution of 50 S ribosomal subunits from Bacillus stearothermophilus.


Records and medical confidentiality.

Records and medical confidentiality.


Recovery of phage T4 from nitrous acid damage.


Recurrent abdominal pain in children.

Recurrent abdominal pain in children.


Red blood cell calcium and magnesium: effects upon sodium and potassium transport and cellular morphology.


Red cell survival studies in patients with unstable haemoglobin disorders.


Reduced litter size associated with aneuploid cell lines in a pair of full-brother Duroc boars.


Reconstruction of the tongue.

Reconstruction of the tongue.


Reduction and separation of nitrate and nitrite by liquid membrane-encapsulated enzymes.


Reduction by anti-inflammatory corticosteroids of clonogenic growth of allogeneic tumour cells in normal and irradiated tissues of the rat. Anti-inflammatory corticosteroids administered to rats in high dosages before intravenous injection of allogeneic tumour cells caused 5-10 fold reductions in "take" and clonogenic growth of the cells in lung and kidney and decreased growth and spread of the cells transplanted to leg muscle. Steroid therapy also reduced the effect of local irradiation of lung tissues in increasing tumour colony efficiency (CFE) in the lungs; it also tended to reduce similar effects of sublethal whole body irradiation. A non-steroidal anti-inflammatory drug, phenylbutazone, also reduced CFE in locally irradiated lungs in the rat.The results obtained indicate that corticosteroids do not stimulate the growth of implanted tumour cells by suppressing host immunity but decrease their clonogenic growth by inhibiting local inflammatory reactions to cell arrest, and similarly to local tissue damage caused by x-irradiation; it is asserted that such inflammatory reactions are growth promoting and thereby stimulate regeneration of stroma (repair) and also support survival and early growth of the tumour cell.


Reduction by pretreatment with dibenamine of hepatotoxicity induced by carbon tetrachloride, thioacetamide or dimethylnitrosamine.


Regional cutaneous metastases in melanoma of the limb.


Regeneration of the vascular system in experimental peripheral nerve grafting.


Regional intrarenal perfusion in man: an assessment with the scintillation camera.


Regional intravascular chemotherapy for experimental liver metastasis.


Red cell indices in thalassemia minor.

Red cell indices in thalassemia minor.


Regional lung function after pneumonectomy.


Regional perfusion and circulation-stop method for chemotherapy of cancer and metastasis.


Regional renogram. A screening test for renal hypertension evaluation.


Regional vagosympathetic control of the heart.


Regional ventilation and gas exchange after hemicorporectomy.


Regression analysis of the spontaneous spike activity of neurons in snail ganglia.


Regulation of metabolic transport in rat and guinea pig liver mitochondria by long chain fatty acyl coenzyme A esters.


Regular structures in membranes. I. Membranes in the endocytic complex of ileal epithelial cells. An "apical endocytic complex" in the ileal lining cells of suckling rats is described. The complex consists of a continuous network of membrane-limited tubules which originate as invaginations of the apical plasma membrane at the base of the microvilli, some associated vesicles, and a giant vacuole. The lumenal surface of this tubular network of membranes and associated vesicles is covered with a regular repeating particulate structure. The repeating unit is an approximately 7.5-nm diameter particle which has a distinct subunit structure composed of possibly nine smaller particles each approximately 3 nm in diameter. The approximately 7.5-nm diameter particles are joined together with a center-to-center separation of approximately 15 nm to form long rows. These linear aggregates, when arranged laterally, give rise to several square and oblique two-dimensional lattice arrangements of the particles which cover the surface of the membrane. Whether a square or oblique lattice is generated depends on the center-to-center separation of the rows and on the relative displacement of the particles in adjacent rows. Four membrane faces are revealed by fracturing frozen membranes of the apical tubules and vesicles: two complementary inner membrane faces exposed by the fracturing process and the lumenal and cytoplasmic membrane surfaces revealed by etching. The outer membrane face reveals a distinct array of membrane particles. This array also sometimes can be seen on the outer (B) fracture face and is sometimes faintly visible on the inner (A) fracture face. Combined data from sectioned, negatively stained, and freeze-etched preparations indicate that this regular particulate structure is a specialization that is primarily localized in the outer half of the membrane mainly in the outer leaflet.


Rehabilitation after myocardial infarction.


Regulation of pyruvate-dehydrogenase interconversion in rat-liver mitochondria as related to the phosphorylation state of intramitochondrial adenine nucleotides.


Reinforced vein patch grafts.

Reinforced vein patch grafts.


Rehabilitation of the inflammatory arthropathies.


Relation between gastrin response to food stimulation and pentagastrin-stimulated gastric acid secretion in normal humans.


Relation between phage sensitivity and symbiotic properties of auxotrophic mutants of Rhizobium meliloti.


Relation between pulmonary gas exchange and closing volume before and after substantial weight loss in obese subjects. Relations between expiratory reserve volume (ERV), closing volume (CV) as a percentage of vital capacity (CV/VC%), and pulmonary gas exchange have been investigated in the sitting and supine postures in eight severely obese subjects before and after substantial weight loss. CV/VC% exceeded predicted values but did not change with posture or weight loss; the increase could have been owing to the smoking habits of the subjects. Arterial oxygen pressure (PaO(2)) was significantly less in the supine than in the sitting posture and improved after weight loss in six subjects. The reduction in PaO(2) was correlated with the extent to which dependent airways were closed within the range of tidal breathing, shown by increasing negativity of ERV-CV as a percentage of VC. A good correlation was also found between PaO(2) and ERV, an easier measurement for routine use. Improvement of pulmonary gas exchange occurred only in those patients who lost weight to within 30% in excess of ideal.


Relationchip of alveolar CO2 and O2 pressures to AaDo2 in normal subjects.


Relationship between carotid sinus pressure and plasma renin level.


Relationship between drug involvement and purpose in life.


Relationship between freezing rate, ultrastructure and recovery in a human diploid cell line.


Relationship between pica and iron nutrition in Johannesburg Black adults.


Relationship between the membrane envelope of rhizobial bacteroids and the plasma membrane of the host cell as demonstrated by histochemical localization of adenyl cyclase. By using adenyl cyclase as a marker enzyme, the relationship between the membrane envelope of the bacteroids of rhizobia and the plasma membrane of the host cell was demonstrated histochemically. Electron-dense deposits were found on the outer surface of the plasma membrane of the host cell and on the inner surface of the membrane envelopes of the bacteroids, but not in vacuole membranes, endoplasmic reticula, Golgi apparatus, and mitochondrial membranes. The results suggest that the membrane envelopes of the bacteroids are closely related to the host plasma membrane, and that entry of the bacteroids into the cytoplasm is in a manner similar to endocytosis.


Relationship of serum lipid concentrations to alcohol consumption.


Relapsing form of subacute necrotizing encephalomyelopathy.


Relationship of calcium to reproductive abnormalities in the laying hen (Gallus domesticus).


Relative affinities of alkali metal ions to the ligands in ionophores.


Relationship of age and mood to monoamine metabolites in cerebrospinal fluid in parkinsonism.


Relative ventilation and perfusion of left versus right lung in mitral stenosis.


Relaxing incisions in the immediate treatment of snakebites of the finger. A case report.


Release of amino acids from the chronically-superfused mammalian cerebral cortex.


Release study of some drugs from polymeric matrices.


Reliability in automatic determination of the ABO group by the groupamatic system.


Reliability of reporting by women taking part in a prospective contraceptive study.


Remotivation for geriatric patients using elementary school students.


Removal of the N alpha-benzyloxycarbonyl group from cysteine-containing peptides by catalytic hydrogenolysis in liquid ammonia, exemplified by a synthesis of oxytocin.


Renal age changes in the rat compared with human renal senescence. An autoradiographic study.


Renacidin irrigation of the ileal conduit: a study of systemic magnesium absorption.


Renal arterial aneurysm not detectable on angiography: a case report.


Renal citrate in the potassium-deficient rat: role of potassium and chloride ions.


Remarks on the morphology of gonadoblastoma.


Renal cortical imaging in 35 patients: superior quality with 99mTc-DMSA.


Renal cortical necrosis: a model for the study of juxtamedullary nephron physiology.


Renal excretion of urea in the dog during onset and subsidence of diuresis.


Renal excretion of N4-acetyl sulphanilamide and N4-acetyl sulphadimidine in goats.


Renal scleroderma and pregnancy.

Renal scleroderma and pregnancy.


Renal expansion in saline loading.

Renal expansion in saline loading.


Renography in the diagnosis of obstructive uropathy due to malignant tumors of the pelvis.


Reoperation after total correction of tetralogy of Fallot.


Reorganization of systems for primary care delivery.


Repeated "occult" spinal subarachnoid hemorrhage and spinal cord ependymoma.


Repeated nucleotide sequences in the loach genome.


Replacement for intraoperative blood loss.


Report on a visit to the institute of Materia Medica of the People's Republic of China.


Replication of Sindbis virus. V. Polyribosomes and mRNA in infected cells. Cells infected with wild-type Sindbis virus contain at least two forms of mRNA, 26S and 49S RNA. Sindbis 26S RNA (molecular weight 1.6 x 10(6)) constitutes 90% by weight of the mRNA in infected cells, and is thought to specify the structural proteins of the virus. Sindbis 49S RNA, the viral genome (molecular weight 4.3 x 10(6)), constitutes approximately 10% of the mRNA in infected cells and is thought to supply the remaining viral functions. In cells infected with ts2, a temperature-sensitive mutant of Sindbis virus, the messenger forms also include a third species of RNA with a sedimentation coefficient of 33S and an apparent molecular weight of 2.3 x 10(6). Hybridization-competition experiments showed that 90% of the base sequences in 33S RNA from these cells are also present in 26S RNA. Sindbis 33S RNA was also isolated from cells infected with wild-type virus. After reaction with formaldehyde, this species of 33S RNA appeared to be completely converted to 26S RNA. These results indicate that 33S RNA isolated from cells infected with either wild-type Sindbis or ts2 is not a unique and separate form of Sindbis RNA.


Representation of the cochlea within the inferior colliculus of the cat.


Reproducibility of the response to secretin and secretin plus pancreozymin in man.


Reproductive physiology of the stallion. IV. Seasonal changes in the testosterone concentration of peripheral plasma.


Rerversible reaction of simple ferrous porphyrins with molecular oxygen at low temperatures.


Research on compounds with antiblastic activity. LVII. Anthramycin and related compounds. VI. Synthesis of pyrrolo(1,2-b)(1,2,5)benzothiadiazepine derivatives.


Resection of massive abdominal panniculus adiposus.


Reserpine inhibition of hypertonic saline-induced changes in the hypothalamic neurosecretory system of the spotted owlet, Athene brama Temminck.


Resistance and blood gas tensions in bronchial asthma.


Resistance of Echinococcus multilocularis to x-ray.


Resistance to high oxygen tension, streptonigrin, and ultraviolet irradiation in the green alga Chlorella sorokiniana strain ors.


Resolution of some 3-(3,4-dihydroxyphenyl)alanine precursors with alpha-chymotrypsin.


Respiratory forces and variations of static lung volumes in healthy subjects.


Respiratory frequency in birds selected for high-and low-oxygen consumption.


Respiratory symptoms in a group of American secondary school students: the overwhelming association with cigarette smoking.


Respiratory failure and isoprenaline.

Respiratory failure and isoprenaline.


Response of newborn infants to added respiratory loads.


Response of vaginal epithelium and the quantitative estimation of its cellular proliferation in ovariectomized rats after a single administration of oestradiol.


Response to pain and stress: a multivariate analysis.


Responses of single units in the intermediolateral nucleus to stimulation of cardioregulatory medullary nuclei in the cat.


Responses recorded from human scalp evoked by cutaneous thermal stimulation.


Restoration of the deformability of "irreversibly" sickled cells by procaine hydrochloride.


Resting membrane potential and ionic distribution in fast- and slow-twitch mammalian muscle. The resting membrane potential and intracellular potassium and sodium concentration of three guinea pig hind limb muscles were studied. These properties are related to the gross color, the speed of contraction, and the biochemically defined fiber type composing the muscle. The resting membrane potential and intracellular content were: white vastus (grossly white, fast-twitch glycolytic) -85.3 mV. potassium 171.9 meq/liter; soleus (grossly red, slow-twitch oxidative) -69.7 mV, potassium 137.5 meq/liter; and red vastus lateralis (grossly red, fast-twitch oxidative glycolytic) -71.7 mV, potassium 139.6 meq/liter. In soleus and red vastus lateralis, the relative permeability of sodium to potassium was 0.041 and 0.036, while in white vastus it was 0.015. These results give us the first exception to the hypothesis that fast-twitch fibers have higher intracellular potassium and higher resting membrane potential than slow-twitch fibers.


Restraint of cholesterol accumulation in tissue pools associated with drastic short-term lowering of serum cholesterol levels by clofibrate or cholestyramine in hypercholesterolemic swine. In this study, young growing swine were made hypercholesterolemic (~300 mg/dl) by feeding milk and eggs for 7 wk. They were then divided into three groups (untreated, clofibrate-treated, and cholestyramine-treated), and the diet was continued for an additional 3-4 wk. A cholesterol balance study was carried out in the terminal week. When the swine were killed, the total carcass content of cholesterol was determined, as well as contents of individual tissues. Both drugs caused a 50% reduction in serum cholesterol levels. The total carcass cholesterol contents were significantly lower in both treatment groups than in the untreated group. The difference was due largely to lower concentrations in the plasma and in bulk tissues. [4-(14)C] Cholesterol was fed 7 days before the animals were killed, and specific activities of cholesterol in individual tissues were determined terminally. These gave a broad spectrum of values in tissues (excluding central nervous system) ranging rather evenly from 33% of plasma specific activity in the aorta to 100% in some tissues. The balance data suggest that cholestyramine reduces the enterohepatic bile acid pool and cholesterol absorption but increases fecal output of bile acids and total body cholesterol synthesis. The balance data, limited to the terminal week, give no indication of the mode of action of clofibrate. Even synthesis was not significantly lower than in the untreated swine.


Restrictions on clinical research.

Restrictions on clinical research.


Retinal degeneration in hemiplegic migraine.


Retinoblastoma and long arm delection of chromosome 13. Attempts to define the deleted segment.


Responses of middle-aged women to maximal cycling exercise.


Reversible binding of dioxygen to mesoporphyrin IX derivatives at low temperatures.


Reversible cold inactivation of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase from rat liver.


Rheumatic fever. V. Prevention of rheumatic fever.


Ribonucleases of beef brain nuclei. Purification and characterization of an alkaline RNAase.


Ribonucleic acid synthesis by isolated viruses of Penicillium stoloniferum.


Ribosomal RNA synthesis in chronic lymphocytic leukaemia. Lymphocytes from patients with chronic lymphocytic leukaemia make large amounts of stable, rapidly labelled high molecular weight RNA, but ribosomal RNA methylation is normal. However, fewer ribosomes are available for protein synthesis than in normal lymphocytes.


Ribosome fractions from normal and methylcholanthrene-treated mouse epidermis.


Richardson's reconditioning and sharpening technique for microtome knives.


Right atrial receptors mediate the adrenocortical response to small hemorrhage.


Roentgenographic techniques in the evaluation of epidermoid carcinoma of the cervix uteri.


Roentgenologic demonstration of anterior mediastinal mass with pericardial and pleural effusion.


Role of bladder infection in the etiology of vesicoureteral reflux in dogs.


Role of brain noradrenaline in the regulation of pituitary-adrenocortical functions.


Rhizopus and Chlamydomucor strains surveyed for milk-clotting, amylolytic, and antibiotic activities.


Role of colostomy in perineal burns.

Role of colostomy in perineal burns.


Role of dietary fat in health.

Role of dietary fat in health.


Role of exdotoxin and bacteria in long-term survival of preserved small-bowel allografts.


Role of insulin and glucagon in obesity.


Role of maternal artifact in fetal heart rate pattern interpretation.


Role of noradrenaline in levodopa reversal of reserpine akinesia.


Role of noradrenaline, 5-hydroxytryptamine and acetylcholine in the hypothermic and convulsive effects of alpha-chlordane in rats.


Role of the clinical dietitian. I. Ideal role perceived by dietitians and physicians.


Role of the clinical dietitian. II. Ideal vs. actual role.


Role of the thyroid gland in blood calcium homeostasis during intestinal calcium absorption in man.


Role of vitamin D metabolites in phosphate transport of rat intestine.


Role of the reticuloendothelial system in the production of alpha-macrofetoprotein in the rat following intravenous injection of beryllium and other particles.


Role of BCG vaccine among American Indians.


Rooming-in.

Rooming-in.


Rosette-forming cells and the immunological response after DNCB, DNP-carrier and oxazolone sensitization.


Rubella vaccinees in a public school system: a four and one-half-year follow-up.


Routine gas chromatographic component profiling of cigarette smoke for the identification of biologically significant constituents.


Runaway pacemaker rhythm after 36 hours of electrical inactivity.


Rupture of esophagus during use of Mengstaken-Blakemore tube.


Rupture of esophagus during use of Sengstaken-Blakemore tube.


RNA metabolism in previtellogenic oocytes of Xenopus laevis.


Rupture of the trachea during laryngo-oesophagectomy.


RNA synthesis in the thymus of the immunologically mature mouse.


RNA synthesis in isolated mitochondria from sea urchin embryos.


RNA-binding protein from rabbit reticulocyte extract.


RNA synthesis specific for an integrated adenovirus genome during the cell cycle.


Sacrococcygeal teratoma in Nigerian infants and children.


Safe limits of hemodilution in cardiopulmonary bypass.


Safety of ethylene oxide gas residuals. II.


Salicylate inhibition of in vitro plasminogen activation by saline extracts of rat tissues.


Salicylate-mediated increase in urate removal during hemodialysis: evidence for urate binding to protein in vivo.


Salmonella typhosa urinary tract infection and xanthogranulomatous pyelonephritis. Case report and review of literature.


San Jose scale: field studies with a sex pheromone.


Sarcoidosis in the Bantu. Necrotizing and mutilating forms of the disease.


Sarcomere length-active force relations in living mammalian cardiac muscle.


Satellite DNA sequences in Drosophila virilis.


Scan evidence of decrease in size of intrahepatic tumors after chemotherapy. A case report.


Scanning electron microscopy of sectioned fungal cells.


Scanning electron microscopy of the subarachnoid space in the dog. II. Spinal nerve exits.


Schistosoma haematobium in the baboon (Papio anubis).


Schistosoma haematobium in Lusaka, Zambia.


School performance of adult schizophrenics, their siblings and age mates.


Scimitar syndrome associated with central nervous system anomalies.


Scintiscanning with gallium citrate 67. Diagnosis of head and neck malignant neoplasms.


Score changes following repeated administration of mental status questionnaires.


Scotopic contrast hues displaced toward blue.


Seasonal factors influencing the location of Bulinus (Physopsis) globosus by miracidia of Schistosoma haematobium in nature.


Screening for carriers of Tay-Sachs disease: A community project. Heterozygotes for Tay-Sachs disease can be distinguished by measuring the serum hexosaminidase activity and calculating the percentage of the heat-labile (A) form. We tested 7565 Ashkenazi Jews in Metropolitan Toronto and found a carrier frequency of 0.071. This figure was similar to the predicted frequency on the basis of caseload over a five-year period. We also found that 15% of women taking oral contraceptives were false-positive carriers. As with pregnant women, these false-positive carriers could be distinguished from true carriers by assaying leukocyte hexosaminidases.


Seasonal histological changes in the testes of a hill-stream teleost, Schizothorax richardsonii (Gray-Hard).


Seaweed extracts: a unique ocean resource.


Secular changes in thyroid uptake.

Secular changes in thyroid uptake.


Secretion of hyperglycaemic hormone from the corpus cardiacum of flying blowflies, Calliphora erythrocephala.


Screening in community control of cardiovascular diseases.


Sebum excretion and melanocyte-stimulating hormone in hypoadrenalism.


Second FEBS-Ferdinand Springer lecture: Membrane active complexones. Chemistry and biological function.


Secretion of phospholipids and cholesterol in the bile of rats. Action of phenobarbitone.


Selection of patients for early discharge after acute myocardial infarction.


Segmental sodium reabsorption in rats with mild and severe volume depletion.


Selective induction of labour following administration of an oral prostaglandin E2 0.5 mg tablet hourly.


Selection of medical students--a burning question.


Selective feminization due to an adrenal carcinoma.


Selective binding of chemically defined antigenic peptides to mouse lymphocytes.


Selective regulation of the blood-brain barrier by sensory input.


Selective sympathetic denervation of the rabbit ductus deferens using 6-hydroxydopamine.


Selective vasoconstriction in carotid vascular bed by methysergide: possible relevance to its antimigraine effect.


Selective elimination in vitro of sensitive cell clones in methylcholanthrene induced sarcoma by vinblastine sulphate.


Selectivity in the reinnervation of iris and adrenal medulla by superior cervical ganglion after transplantation under the kidney capsule.


Self-actualization of female narcotic drug addicts.


Semi-automated system for the study of the release of drugs from solid dosage forms.


Semen characteristics of different breeds of geese in Hungary.


Self-induced glomerulonephritis.

Self-induced glomerulonephritis. A patient is described who developed renal failure due to a severe proliferative glomerulonephritis with hypocomplementaemia and cryoglobulinaemia while repeatedly injecting herself with diphtheria, pertussis, and tetanus vaccine (D.P.T. vaccine). After stopping the antigen administration there was recovery of renal function, complement values returned to normal, and cryoglobulin could no longer be recovered from the sera. The pathogenesis of the glomerulonephritis is discussed.


Senior medical consultants. The right men in the right places at the right time.


Semichronic toxicity study of sodium bromide in rats.


Sensations of finger movement elicited by pulling upon flexor tendons in man.


Sense organs on the antennae of two species of thrips (Thysanoptera, insecta).


Sensitivity of the larval stage of Spodoptera Littoralis boisd to a juvenile hormone analogue.


Sensitivity of different target cells to the killing action of peripheral lymphocytes stimulated by autologous lymphoblastoid cell lines.


Sensory generalization in instrumental defensive reflexes in dogs. Five dogs were preliminarily trained in the situation of classical defensive conditioned reflexes. The training sharply impeded the subsequent instrumental avoidance conditioning (with the stimulus applied to one leg and the avoidance movement accomplished by another leg). However, following the elaboration of the instrumental avoidance to one of the signals previously used in the classical situation, the other signals of the classical conditioned reflex evoked the instrumental avoidance reaction at once, without any preliminary training. When the animals which had been trained under "instrumental" conditions were brought back to classical situation they revealed an extreme inertness of manifestation of the instrumental avoidance reflex. In another experimental series the same dogs were trained to perform an escape reaction. When the stimulating electrodes were displaced to new receptive areas, most dogs made use of their previous experience and performed the acquired instrumental movement, thus escaping the electric shock.


Sensorimotor dominance and the right-ear advantage in mandibular-auditory tracking.


Separation of anthraquinone glycosides and aglycones using electropaperography.


Septic embolic nephritis in a dolphin caused by Staphylococcus aureus.


Sequelae of combined amputation and conization of the cervix.


Sequence analysis of fluorescamine-stained peptides and proteins purified on a nanomole scale. Application to proteins of bacteriophage MS2.


Sequence of a repressor-binding site in the DNA of bacteriophage lamda.


Sequence of regional filling during a tidal breath in man.


Sequence of the cysteine-containing portion of histone F2al from the sea urchin Parechinus angulosus.


Sequential oligopeptides. Conformational studies of the oligopeptides and a polypeptide with the repeating sequence L-norvalyl-glycyl-L-proline.


Sequential oligopeptides. Synthesis and characterization of the oligopeptides and a polypeptide with the repeating sequence L-norvalyl-glycyl-L-proline.


Sequential vs simultaneous two-channel signal detection: more evidence for a high-level interrupt theory.


Serological evidence for the association of bovine respiratory syncytial virus with respiratory tract disease in Alabama cattle. A serological investigation for neutralizing antibody to bovine respiratory syncytial virus (BRSV) was conducted using an antigenically related human strain of respiratory syncytial virus. Results demonstrated the effectiveness of the procedure. Sixty-seven percent of healthy, adult cattle tested were found to have antibody to BRSV. Calves in several herds were exposed to conditions to encourage development of respiratory tract disease. In three herds in which respiratory tract disease subsequently developed, the incidence of BRSV seroconversions approached 100%. In a herd in which no respiratory tract disease was detected, BRSV seroconversions indicated a high incidence of subclinical infections. It was concluded that, in this country as has been shown in others, BRSV is probably a significant pathogen of the bovine respiratory tract.


Serological evidence of A2 Hong Kong influenza in Sudan.


Serotonin distribution in the nuclei of the rat hypothalamus and preoptic region.


Serum alpha-tocopherol in pregnancies with normal or pathological outcomes.


Serum and intestinal fluid immunoglobulins in patients with giardiasis.


Serum and parotid salivary IgA in chronic bronchitis and asthma.


Serum cholesterol and serum triglyceride levels in Australian adolescent males.


Serum cholesterol determination by mass fragmentography.


Serum concentration and half-life of rifampicin after simultaneous oral administration of aminosalicylic acid or isoniazid.


Serum concentration and urinary excretion of doxycline in normal subjects and patients with renal insufficiency.


Serum haptoglobins: a preoperative detector of metastatic renal carcinoma.


Serum oestradiol-17 beta in normal women. Serum concentrations of oestradiol-17β were measured by radio-immunoassay during 40 menstrual cycles from 38 normal premenopausal women. Repeated samples were studied from 25 normal postmenopausal women. The method was highly specific and extremely sensitive. In premenopausal women the pattern of serum oestradiol-17β was remarkably constant but the concentrations varied with age. Women in the fourth decade of life had significantly higher concentrations of oestradiol-17β than either younger or older women. In postmenopausal women the concentration of oestradiol-17β was consistently very low.


Serum sickness: a case report.

Serum sickness: a case report.


Serum thyroxine as an index of thyroid function.


Serum transfer of immunity to Fasciola hepatica in rats.


Serum triiodothyronine and thyroid-stimulating hormone levels in a patient with iodide-induced goiter.


Serum IgE concentration in atopic dermatitis. Relationship to severity of disease and presence of atopic respiratory disease.


Serum IgE levels in protozoal and helminthic infections.


Sex differences in self-reported anxiety for different situations and modes of response.


Severe neonatal citrullinaemia.

Severe neonatal citrullinaemia.


Seven cases of lead poisoning at a Northern Territory drilling site.


Sex in the aged.

Sex in the aged.


Sex pheromones of the moth, Archips podana: isolation, identification and field evaluation of two synergistic geometrical isomers.


Sex ratio among normal sibs of persons with Turner's syndrome.


Sextuplet gestation. A case report.

Sextuplet gestation. A case report.


Sexual aberrance in male adolescents manifesting a behavioral triad considered predictive of extreme violence: some clinical observations.


Shedding of foot pads by black bears during denning.


Short and long-term results of the treatment of aplastic anemias with nandrolone decanoate.


Short-term insight psychotherapy for hysterical personalities. Stages of the therapeutic process.


Side-chain effect on conformation of ionizable polypeptides in aqueous solution.


Short-term course and prognosis of Crohn's disease. An analysis is presented of the course and outcome of the initial referred attack in a group of 332 patients with Crohn's disease treated at the General Infirmary at Leeds from 1939 to 1968 inclusive. A further 50 cases were excluded on the basis of insufficient diagnostic evidence: usually such patients had acute terminal ileitis. Only 5% of patients achieved full remission on conservative management, and most eventually came to surgery. The overall fatality rate was some 3.3% and this was affected chiefly by the severity of attack and the age of the patient. The severity of attack was classified as mild, moderate, or severe according to a system which took into account factors such as bowel habit, rectal bleeding, abdominal pain, pulse rate, temperature, haemoglobin, and weight. In attacks graded as ;mild', no deaths occurred; in those graded ;severe' the fatality rate was 8.8%. Similarly, whilst no patient under 20 years of age died, the fatality rate in the over 60s was some 14.8%. Further comparison between the present group of 332 patients and an earlier series of 204 patients suffering from ulcerative colitis (Watts, de Dombal, Watkinson, and Goligher, 1966a) shows considerable differences in the course and prognosis of the two diseases. In particular 70% of patients with ulcerative colitis achieved remission on conservative management alone whereas only 5% of Crohn's disease patients did so. These differences, and in particular the poor response to conservative therapy, are discussed, together with their implications for management.


Sigmoid myotomy: a retrospective study of 28 patients.


Significance and prognosis of an isolated late systolic murmur: a 9- to 22-yearyearfollow-up.


Significance of first degree heart block (prolonged P--R interval) in bifascicular block.


Significance of prolonged peripheral vasoconstriction after open-heart surgery.


Significance of social demographic data for rehospitalization of schizophrenic patients.


Significance of the local sweat response in the diagnosis of leprosy.


Simple dioxygen heme complexes formed in N,N-dimethylformamide.


Similarities between one of the multiple forms of peptide hydrolase purified from brush-border and cytosol fractions of guinea pig intestinal mucosa.


Simple vessel for freeze drying.

Simple vessel for freeze drying.


Simplified apparatus for vertical slab electrophoresis in polyacrylamide gels.


Simple, semiquantitative test for partial factor XIII (FSF) deficiency.


Simplified analogs of lysergic acid. V. Derivatives of N,N-diethyl-1-methyl-9H-indeno-1,2,3,9a-tetrahydro(2,1-b)pyridine-3-carboxamide.


Simultaneous analysis of 2,3,4,6-tetrachloroanisole, pentachloroanisole and the corresponding chlorophenols in biological tissue.


Simultaneous bilateral carcinoma of ureter.


Simultaneous calf and thigh blood flow measurements by selective femoral vein occlusion plethysmography.


Simultaneous direct operations for bilateral internal carotid artery aneurysms.


Single-handed practices.

Single-handed practices.


Singlet oxygen. The suppression of its production in dismutation of superoxide ion by superoxide dismutase.


Sinusoidal fetal heart pattern. A sign of fetal hypoxia.


Site of biliary phospholipid absorption in the small intestine of the rat.


Size reduction in bighorn sheep (Ovis canadensis) at the close of the Pleistocene.


Sitosteryl-beta-D-(6-O-fattyacyl)-glucopyranosides from the crude phosphatides of maize.


Skeletal disease and locomotor problems in turkeys.


Skin and rectal temperatures during ether and halothane anesthesia in infants and children.


Small-bowel obstruction caused by abdominal aortic aneurysm.


Snail findings from an experimental mollusciciding programme to control Schistosoma mansoni transmission on St. Lucia.


Slopes of dose-response curves to norepinephrine in isolated strips of the cat's spleen.


So who needs teaching?

So who needs teaching?


Social factors and epileptics in prison.


Social background and breastfeeding among American mothers. Using 1965 National Fertility Survey data, the national trends and patterns of breastfeeding among American mothers are examined.  A review of the literature finds most results of studies to be inconsistent.  In this study the total sample was 4918 mothers with first births.  The general conclusion is that breastfeeding has been declining since the turn of the century.  50% breastfed their first child.  Black and Latin American mothers are about 7 points above the average.  Northwest European (English and German) mothers had higher rates than mothers from Irish, Slavic, French or Italian backgrounds.  Being a Catholic makes a mother less likely to breastfeed her first baby for most all nationality groups except Latin American.  Farm mothers were much more likely to have breastfed their first baby than nonfarm mothers, 64% to 49%.  The South and West geographical districts were 6-8 points above the grand mean while the Midwest and Northeast are below it.  Only 40% of mothers in the Northeast breastfeed.  By education, the lowest educational category (6 years or less) have the highest breastfeeding rates, 74%, which declines to high school graduates who have a low of 44%, then rises with a college education.  The college educated group is the next highest category after the lowest educated group.  White collar workers and service employed were the highest groups among occupations of those breastfeeding.


Sodium and potassium in human red cells: variations among centrifuged cells.


Sodium dithionite reduction of flavin.

Sodium dithionite reduction of flavin.


Solitary autonomous thyroid nodules.

Solitary autonomous thyroid nodules.


Solitary intrarenal cyst causing hypertension.


Soluble and membrane catechol-o-methyl transferases in red blood cells of schizophrenic patients.


Soluble protein factors and ribosomal subunits from yeast. Interactions with aminoacyl-tRNA.


Solubilized receptor for intrinsic factor-Vitamin B12 complex from guinea pig intestinal mucosa. the absorption of vitamin B(12) in many animals requires its prior association with intrinsic factor (IF) and attachment to a specific receptor in the intestine. Employing Triton X-100, we have solubilized from guinea pig ileum a factor that binds intrinsic factor-vitamin B(12) complex (IF-B(12)). This binding factor was soluble to the extent that it was not sedimented by centrifugation at 100,000 g for 1 h and was small enough to enter the included volume of a Sepharose 4-B column. Furthermore, the ileal extract contained no microfine particles of membrane upon electron microscopic search. When a portion of the extract was incubated with a mixture of gastric juice and (57)Co-labeled vitamin B(12), a portion of the radioactivity was excluded from a Sephadex G-200 column. When gastric juice from a patient with a congenital abnormality of IF that prevented its binding to intestine was substituted for normal human gastric juice, radioactivity was not excluded from the gel, indicating failure of this abnormal IF-B(12) to bind to the intestinal extract. These data suggested the presence of a specific binder of IF-B(12) in the ileal mucosal extract. The reactions of normal IF-B(12) with the solubilized binding factor and with the membrane-bound "receptor" had several characteristics in common, including calcium dependence, temperature independence, and pH optimum near neutral. Extracts from the distal intestine showed more activity than did those from the proximal. The solubilized binding facter seemed specific for IF-B(12) in that it was not blocked by prior incubation with excesses of either free vitamin B(12) or IF. Binding activity of the extract was decreased by incubation at pH 2.0, by heating to 56 degrees C, and by incubation with chymotrypsin and dithiothretiol. Incubation with trypsin, neuraminidase, and sulphydryl blockers did not affect it. The Triton X-100 extract of guinea pig ileal mucosa contains a specific binding factor that probably is the receptor for IF-B(12). This appears to be a protein with function dependent on peptide and disulphide linkages.


Solution properties of synthetic polypeptides. 18. Helix-coil transition of poly-N5-(2-hydroxyethyl)L-glutamine.


Solvent effects on reversible formation and oxidative stability of heme-oxygen complexes.


Solvation of lysozyme and beta-lactoglobulin in aqueous guanidine hydrochloride solutions.


Solvent effects on the orientation of naphthalene rings in the side chain of poly-gamma-1-naphthylmethyl-L-glutamate.


Some basic postulates of "state" psychology.


Some aspects of the left atrial sound.

Some aspects of the left atrial sound.


Some aspects of equine dental decay.

Some aspects of equine dental decay.


Some developmental aspects of primary process manifestations in the Rorschach.


Some effects of low oxygen partial pressures on the development of Calliphora vomitoria;.


Some environmental factors affecting free amino acid composition in six varieties of peanuts.


Social medicine in Poland: a personal view.


Some cardiovascular and respiratory effects of four non-barbiturate anaesthetic induction agents.


Some metabolic functions of liver in patients with advanced non-hepatic cancer.


Some modifications to existing iridium-192 wire after-loading techniques.


Some observations on adolescent drug use. Therapeutic implications.


Some normal modes of an infinite hexagonal array of identical circular dielectric rods.


Some observations on the action of delta 9-THC on the human organism.


Some opportunities and issues in medicine.


Some remarks on persecution pathology.

Some remarks on persecution pathology.


Some personality correlates of the conjugate lateral eye-movement phenomenon.


Some sex-role stereotypes and personal preferences, 1950 and 1970.


Some properties of noradrenaline uptake in non-innervated vascular smooth muscle.


Some sociological aspects of nutrition and development in South Africa.


Something 'big' about small town practice.


Some solubility studies of erythropoiesis regulatory factors (ERF)s.


Sound and sound emission apparatus in puerulus and postpuerulus of the western rock lobster (Panulirus longipes).


Sound production in scolytidae: 'rivalry' behaviour of male Dendroctonus beetles.


Sparganum growth factor in new world Spirometra spp.


Spatial filtering to improve transverse tomography.


Special cutaneous receptor organs of fish. VII. Ampullary organs of mormyrids.


Specialty choices of medical graduates taking anesthesiology preceptorships: a follow-up study.


Species differences in the excretion of papaverine metabolites.


Special prosthetic replacement in metastatic and other bone tumors.


Species differences in the acute toxicity and tissue distribution of DDT in mice and hamsters.


Specific heat measurements on lysozyme, chymotrypsinogen, and ovalbumin in aqueous solution and in solid state.


Specific TLC determination of trimethoprim and sulfamethoxazole in plasma.


Some problems of ovarian tumour classifications.


Specificity of pyridoxine (pyridoxamine) 5'-phosphate oxidase for flavin-phosphates.


Specificity of some plant lectins in the differentiation of animal blood.


Spectral and energetic characteristics of the photoactive particles obtained from chromatophores of the green bacterium Chlorobium limicola.


Spectral evaluation of the electroencephalogram: power and variability in chronic schizophrenics and control subjects.


Spectrophotometric determination of pivampicillin hydrochloride.


Spectrophotometric determination of resorcinol in some pharmaceutical preparations.


Spectroscopic properties of protoheme complexes undergoing reversible oxygenation.


Speed of movement in relation to period of the electroencephalogram in normal children.


Spektrophotometric determination of phentolamine in some pharmaceutical preparations.


Sperm's morphologic survival after 16 days in the vagina of a dead body.


Spherical pneumonia.

Spherical pneumonia.


Spermine and choline identification by thin-layer chromatography.


Spinal cord compression in childhood.

Spinal cord compression in childhood.


Sphincteroplasty for postcholecystectomy syndrome.


Spindle-cell carcinoma of the oral mucosa. A light and electron microscopic study of apparent sarcomatous metastasis to cervical lymph nodes.


Spirometric data, pulmonary ventilation and gas exchange at rest and during exercise in adult patients with tetralogy of Fallot.


Splenic circulatory dynamics in congestive splenomegaly.


Splenic metastases. Frequencies and patterns.


Spongy degeneration of grey matter in 3 children. Neuropathological report.


Spontaneous antilymphoma reaction of preleukaemic AKR mice is a non-T-cell killing.


Spontaneous retroperitoneal hemorrhage due to renal cell carcinoma.


Stability of normal human IgG in saline and glycine solutions.


Stability of the brain fatty acid pattern in adult rats during extreme starvation.


Stability of the intracranial circulation in an altered gravitational field.


Stabilization of native structure by the closed disulfide loop of staphylococcal enterotoxin B.


Stable and labile products of mitochondrial protein synthesis in vitro.


Staff conference: Meharry Medical College: Endometrial stromal sarcoma.


Stage classification and end results reporting for carcinoma of the colon and rectum.


Stainless stell mesh--a neglected implant for inguinal hernia repair.


Standardization and interpretation of the electromechanical properties of bone.


Standardization of electrosurgical lesions.


Standardization of forensic drug analyses.


Staphylococcal pneumonia in children. An analysis of 30 cases.


Static mechanical behavior of bronchi in excised dog lung.


Statistical inference on markov process of neuronal impulse sequences.


Status and trends of the NIH extramural research support program.


Statistical considerations in the estimation of enzyme kinetic parameters by the direct linear plot andother methods. The statistical implications of the direct linear plot for enzyme kinetic data, described in the preceding paper (Eisenthal & Cornish-Bowden, 1974), are discussed for the case of the Michaelis-Menten equation. The plot is shown to lead directly to non-parametric confidence limits for the kinetic parameters, V and K(m), which depend on far less sweeping assumptions about the nature of experimental error than those implicit in the method of least squares. Median estimates of V and K(m) can also be defined, which are shown to be more robust than the least-squares estimates in a wide variety of experimental situations.


Status of fulguration and cryosurgery in the management of colonic and rectal cancer and polyps.


Status report: national blood policy.

Status report: national blood policy.


Stereochemistry of cobalt porphyrins. I. The structure and characterization of 2,3,7,8,12,13,17,18-octaethylporphinatobis(3-methylpyridine)cobalt(II).


Stereochemistry of cobalt porphyrins. II. The characterization and structure of meso-tetraphenylporphinatobis(imidazole)cobalt(3) acetate monohydrate monochloroformate,(Co(Im)2(TPP))(OAc)-H2O-CHCl3.


Stereochemistry of cobalt porphyrins. 3. The structure of 2,3,7,8,12,13,17,18-octaethylporphinato(1-methylimidazole)-cobalt(II). A model for deoxycoboglobin.


Stereochemistry of low-spin cobalt porphyrins. VI. Molecular stereochemistry of (1,2-dimethylimidazole)-alpha, beta, gamma, delta-tetraphenylporphinatochobalt(II).


Stereoelectronic properties and reactivity of the tetrahedral intermediate in amide hydrolysis. Nonempirical study of aminodihydroxymethane and relation to enzyme catalysis.


Stereoselective epoxidation of octadiene catalyzed by an enzyme system of Pseudomonas oleovorans.


Stereoselective epoxidations of acyclic allylic alcohols by transition metal--hydroperoxide reagents. Synthesis of dl-C18 Cecropia juvenile hormone from farnesol.


Stereospecificity of lipases. Enzymic hydrolysis of enantiomeric alkyl diacylglycerols by lipoprotein lipase, lingual lipase and pancreatic lipase.


Steric and electronic effects on carbon-13 nuclear magnetic resonance alpha, beta and gamma shifts and fluorine-19-carbon-13 coupling constants in 9 alpha-substituted cortisol derivatives.


Sterilization and disinfection of heat-sensitive equipment.


Sternal splitting midline incision.

Sternal splitting midline incision.


Sternal resection for chondrosarcoma.

Sternal resection for chondrosarcoma.


Steroid alkaloid and sapogenin constituents of Solanum laciniatum Aiton grown in Egypt.


Steroid alkaloid and sapogenin constituents of Solanum laciniatum.


Steroidal adducts. VI. Steroids as probes of the relative reactivities of enophiles and dienophiles. Reactions of dicyanoacetylene with ergosterol derivatives.


Steroids and related natural products. 88. Synthesis of periplogenin.


Sterol content and squaline-2(3)-epoxide-lanosterol cyclase activity in human foetal brain during early and mid-gestation.


Stimulation of amino acids incorporation into rat liver nonhistone chromatin proteins after treatment with diethyl-nitrosamine.


Stimulation of cholesterogenesis by ascorbic acid in adrenal of rats fed vitamin A.


Stimulation of glucagon and insulin secretion by acetylcholine infused intrapancreatically.


Stimulation of hepatic drug-metabolizing enzymes by DDT, polycyclic hydrocarbons or phenobarbital in adrenalectomized or castrated mice.


Stimulation of lipid synthesis in reticulocytes as a response to membrane damage.


Stimulation of thyroid polydisperse nuclear RNA by thyrotropin.


Storage of stock cultures of filamentous fungi, yeasts, and some aerobic actinomycetes in sterile distilled water. Castellani's procedure for maintaining cultures of filamentous fungi and yeasts in sterile distilled water was evaluated. Four hundred and seventeen isolates of 147 species belonging to 66 genera of filamentous fungi, yeasts, and aerobic actinomycetes were maintained in sterile distilled water at room temperature over periods ranging from 12 to 60 months in four independent experiments. Of the 417 cultures, 389 (93%) survived storage in sterile distilled water. The selection of good sporulating cultures and sufficient inoculum consisting of spores and hyphae suspended in sterile distilled water were the most important factors influencing survival in water over a longer period of time. The technique was found to be simple, inexpensive, and reliable.


Storage and release of acetylcholine in a sympathetic ganglion. 1. The hypotheses of preferential release of newly synthesized acetylcholine (ACh) and two compartment storage of transmitter in the cat superior cervical ganglion have been re-examined by testing, first, the assumption that ganglionic ACh stores do not alter during a 20 min rest following 60 min preganglionic nerve stimulation at 20/s, and secondly, the implication that the rate of ACh release should be high near the onset of activity and decline to a lower rate with time irrespective of the frequency of stimulation.2. The ganglionic ACh stores were found to increase by 38 +/- 8% within 20 min following 60 min preganglionic nerve stimulation at 20/s, and this extra ACh was releasable.3. The rate of ACh release from ganglia perfused with cat plasma and stimulated at 4/s increased over the first 5 min of stimulation to reach a 27% higher rate that was maintained.4. Correction of the original data to allow for the post-activation increase in ACh stores suggests that newly synthesized ACh equilibrates with most of the preformed stores. The time course of ACh release at 4/s does not support the two compartment model as currently formulated.5. These findings resolve in part a conflict between the physiological data and a recent hypothesis for ACh storage based on ganglion morphology.


Strain differences in drinking in inbred mice during ad libitum feeding and food deprivation.


Stress arteriography.

Stress arteriography.


Strained heterocyclic compounds. 5. The synthesis of (bromochloro(N,N-pentamethylenecarbamoyl) methyl)-phenylmercury and its thermal decomposition to a chloro-beta-lactam.


Stress convulsions.

Stress convulsions.


Structural basis for inhibition of protein synthesis by the aminoacyl-aminohexosyl-cytosine group of antibiotics.


Structural difference in sites on surface membrane of mature and immature erythrocytes.


Structural identification of haemoglobin, E in ethnic groups from Sri Lanka.


Structural studies on cross-linked regions of elastin.


Structure and activity of hepatitis B antigen (HBAg). 2. Amino acid composition of an active subunit of HBAg.


Structure and conformation of 4-peroxycyclophosphamide. A cytotoxic oxidation product of cyclophosphamide.


Structure and function in urinary bladder of foetal sheep. 1. The structure and function of the epithelial lining of the urinary bladder of sheep foetuses was investigated by electron microscopic studies made in conjunction with a series of experiments in which the permeability of the bladder to sodium and water was measured in vitro. Measurements were made at gestational ages ranging from 50 to 141 days (term = 147 days) Osmolarity and electrolyte concentrations of urine found in the foetal bladder were also measured.2. The development of tight junctions between the bladder epithelial cells was investigated by incubating the tissue with solutions containing 1 mM-LaCl(3) on the mucosal surface. No penetration of the junctions by lanthanum was observed in foetuses of 90 days or older. In younger bladders, the epithelial layer was stripped by treatment with lanthanum, but tight junctions appeared to be fully developed in early bladders incubated without lanthanum.3. The surface structure of the luminal (mucosal) plasmalemma was fully developed at 50 days.4. Unidirectional fluxes of labelled sodium and water were measured with identical solutions bathing the two surfaces of the bladder wall. No net water movement occurred; the mean ratio of efflux to influx in nine bladders was 1.002 +/- 0.039 (S.E. of mean). Under these conditions, the flux ratio for sodium was 1.735 +/- 0.143 (S.E. of mean) in twelve bladders.5. Antidiuretic hormone (ADH) had no effect on net water movement but reduced the net efflux of sodium so that the flux ratio became 1.285 +/- 0.255 (S.E. of mean) n = 8. ADH also had a striking effect on the structure of the epithelium, causing marked swelling of the intercellular spaces. The tight junctions remained an effective barrier to lanthanum penetration under these conditions; lanthanum was not observed in the enlarged spaces.


Structure and function of the larval eye of the sawfly, Perga.


Structure and function of the mantle cavity of Biomphalaria glabrata (Mollusca: Pulmonata).


Structure and physiology of the locust femoral chordotonal organ.


Structure and function of the olfactory organs in the fish Sisor rabdophorus Ham.


Structure and protein distribution for the capsid of Caulobacter crescentus bacteriophage phiCbK.


Structure of coformycin, an unusual nucleoside of microbial origin.


Structure of sensilla, olfactory perception, and behaviour of the bedbug, Cimex lectularius, in response to its alarm pheromone.


Structure of the nymphal spiracle and its formation in the pharate adult Haemaphysalis (Kaiseriana) longicornis Neumann (Ixodoidea: Ixodidae).


Structure of the polysaccharide antigen of Eubacterium saburreum, strain L44.


Structure of Micrococcus diversus after freeze-etching.


Structure-activity relationships for antiviral benzimidazoleureas.


Structure-activity relationships of some arylidenemalononitriles and beta-nitrostyrenes as sensory irritants.


Structured learning therapy with transfer training for chronic inpatients.


Structures on the antennal flagellum of a katydid, Neoconocephalus ensiger (Orthoptera, Tettigoniidae).


Student problems in Japan.

Student problems in Japan.


Students as contributors to the instructional process.


Studies in serum digoxin.

Studies in serum digoxin.


Studies in impedance audiometry. 3. Middle ear disorders.


Studies of deoxyribonucleoproteins progressively depleted of proteins in solutions of variousionic strengths.


Studies of molecular-weight distribution for hydrolysis products from some Klebsiella capsular polysaccharides.


Studies of infants postnatally exposed to methylmercury.


Studies of hemoglobin denaturation and Heinz body formation in the unstable hemoglobins. The sequential changes that occur during the precipitation on mild heating of the unstable hemoglobins, Hb Christchurch, Hb Sydney, Hb Köln, and Hb A, were examined with particular attention to the possibility of an accompanying oxidative process. Hb Christchurch, Hb Sydney, and Hb A precipitated with equal amounts of alpha- and beta-chains and full heme complement. Hb Köln, however, was one-half hemedepleted and showed a slight excess of precipitated beta-chains. In all cases the spectrum of the precipitated material was typical of a hemichrome. There was no evidence that sulfhydryl oxidation contributed to the precipitation process. Reduced glutathione was unable to protect the hemoglobin against precipitation, and mixed disulfide formation between the precipitating hemoglobin and glutathione was insignificant, even in the presence of excess glutathione. No blockade of beta93 cysteines could be demonstrated in the unstable hemoglobins. Precipitation of oxyhemoglobin and carboxyhemoglobin in all cases gave nonspecific oxidation of approximately two of the six hemoglobin sulfhydryl groups to give intra- and intermolecular disulfide bonds. Single alpha- and beta-chains, plus polymers of up to five or six chains linked by disulfide bridges, were demonstrated by polyacrylamide gel electrophoresis. This disulfide oxidation was not observed with deoxy- or methemoglobin and did not appear to influence the rate of precipitation. These findings fit the theoretical prediction that autoxidation of oxy- and carboxyhemoglobin is accompanied by formation of a free radical, with the reactions of this free radical being confined intramolecularly.Together, these results are in keeping with predictions based on the known structural abnormalities of the unstable hemoglobins, all of which result in greater molecular flexibility. Our findings support the conclusion that the usual precipitating event is altered bonding at the heme to give the formation of hemichromes. There is no evidence of an accompanying oxidative process that could pose a threat to the integrity of the red cell.


Studies of multipolar mitoses in euploid tissue cultures. II. Somatic segregation of the sex chromosomes.


Studies of the activity of subunits of aspartate 4-decarboxylase immobilized on sepharose.


Studies of the human testis. IV. Testicular 20 alpha-hydroxysteroid dehydrogenase and steroid 17 alpha-hydroxylase.


Studies of the metabolism of asialotransferrins: evidence that transferrin does not undergo desialylation in vivo.


Studies of the metabolism of asialotransferrins: the mechanism for the hypercatabolism of human asialotransferrin in the rabbit.


Studies of the role of red cell membrane peroxidation in paroxysmal nocturnal haemoglobinuria (PNH).


Studies on allergens of horse epithelium with two variants of RAST.


Studies on convulsive disorders in young children. IV: Incidence of convulsions among siblings.


Studies on antigenic competition. 3. Effect on antigenic competition on antibody affinity.


Studies on cyclic dipeptides. I. Thermodynamics of the cis-trans isomerization of the side chains in cyclic dipeptides.


Studies on further attenuated live measles vaccine. VIII. Estimated duration of immunity after vaccination without natural infection.


Studies on gallic acid esters formed by the extraction of Paeonia peregrina Mill.


Studies on ghosting, an important source of error in the quantitative estimation of free volatile fatty acids by GLC. I. Occurrence of ghosting and factors influencing it.


Studies on ghosting, an important source of error in the quantitative estimation of free volatile fatty acids by GLC. II. Effect of sample VFA concentration on ghosting magnitude and effectiveness of remedies to limit ghosting.


Studies on hair roots for carrier detection in hypoxanthine-quanine phosphoribosyl transferase deficiency.


Studies on heme transfer from microsomal hemoproteins to heme-binding plasma proteins.


Studies on marine microorganisms. 3. Transport of spores of actinomycete into shallow sea mud and the effect of salt and temperature on their survival.


Studies on ophthalmic suspensions containing steroids.


Studies on phytohemagglutinins. XX. Isolation and characterization of hemagglutinins from scarlet runner seeds (Phaseolus coccineus L.).


Studies on silk fibroin. III. Gel filtration study of fibroins.


Studies on orchidaceae alkaloids. XXXIX. Isolation of (minus)-cryptostyline I, II, 3 and two quaternary salts from cryptostylis erythroglossa hayata. Biosynthetic studies of (minus)-cryptostyline I.


Studies on the bacterial flora of Hippelates pusio (Diptera: Chloropidae).


Studies on sugar intake and overweight in South African Black and White schoolchildren.


Studies on the biological properties of coelomic fluid of sea urchin. II. Naturally occurring hemagglutinin in sea urchin.


Studies on the biliary excretion mechanisms of drugs. II. Biliary excretion of thiamphenicol, chloramphenicol and their glucuronides in the rat.


Studies on the cellular transformation in carcinogenesis.


Studies on some aspects of the neuropharmacology of butylurea.


Studies on the biosynthetic pathway of human P erythrocyte antigens using somatic cells in culture.


Studies on the conformations and interactions of elastin. Proton magnetic resonance of the repeating tetramer.


Studies on the decrease in bile flow produced by sulfobromophthalein.


Studies on the distribution of (1-14C) ascorbic acid and (1-14C) dehydroascorbic acid in guinea pigs after oral application.


Studies on the disulfide bonds of glycoprotein hormones. Locations in the alpha chain based on partial reductions and formation of 14C-labeled S-carboxymethyl derivatives.


Studies on the effect of selective membrane filtration on the differentiation of tissue cultures.


Studies on the heparin sulphamidase activity from rat spleen. Intracellular distribution and characterization of the enzyme. A sulphamidase activity present in rat spleen capable of hydrolysing N-[(35)S]sulphated heparin was studied. This activity was associated with the lysosomal fraction. Studies in vivo showed that the rat is capable of significantly desulphating heparin. Lysosomes in all the major tissues can effectively accumulate heparin. The heparin sulphamidase and arylsulphatase activities from rat spleen were separated by isoelectric focusing. Heparin sulphamidase was a distinct entity from all the arylsulphatase activities.


Studies on the inhibitory effect of concanavalin A on the neuraminidase activity of influenza A virus strains.


Studies on the mechanisms of polyploidization of Ehrlich ascites tumour during the course of heterotransplantation into rats.


Studies on the lipid metabolism using 14C-1-palmitate in fetal rats.


Studies on the mitochondrial gene. I. The recombination of mitochondrial drug resistances.


Studies on the mode of action of polyoxins. VI. Effect of polyoxin B on chitin synthesis in polyoxin-sensitive and resistant strains of Alternaria kikuchiana.


Studies on the origin and composition of yolk in Oxya velox (Orthoptera).


Studies on the peripheral mode of action of dihydroergotamine in human and canine veins.


Studies on the photoreactions (365 nm) between DNA and some methylpsoralens.


Studies on the permeability to water, sodium, and chloride of the hydatid cyst of Echinococcus granulosus.


Studies on the riboflavin, niacin, pantothenic acid and choline requirements of young Bobwhite quail.


Studies on the role of heme in the regulation of delta-aminolevulinic acid synthetase during fetal hepatic development.


Studies on the NZB mouse thymus. I. Thymus weight relationships to age and body weight from birth to old age.


Studies on the synthesis of liver phospholipids and the turnover of plasma phospholipids in pregnant rats using radioactive palmitate.


Studies on Hendersonula toruloidea isolated from human skin and nail.


Studies on Onchocerca cervicalis Railliet and Henry 1910. 3. Morphological and taxonomic studies on Onchocerca cervicalis from British horses.


Studies on Onchocerca cervicalis Railliet and Henry, 1910 microfilariae in the jird, Meriones unguiculatus.


Studies with Brugia pahangi. 5. Structure of the cuticle.


Studies on 5'-nucleotidase histochemistry. II. Differences in 5'-nucleotidase activity in stratified squamous epithelia and skin appendages of mouse, rat and guinea pig.


Studies with Brugia pahangi. 6. The susceptibility of male and female cats to infection.


Study of possible correlations between body weights and brain parameters in neonatal and mature rats.


Study of U.S. medical school applicants, 1972-73.


Styles of leadership among nurses.

Styles of leadership among nurses.


Subacute brain-stem encephalitis.

Subacute brain-stem encephalitis. A 65 year old man developed progressive signs of pontine and medullary dysfunction with striking bilateral paralysis of lateral gaze, dysarthria, dysphagia, and ataxia. A respiratory death occurred seven months from the onset. Pathological examination revealed focal brain-stem changes of perivascular lymphocytic cuffing, microglial infiltration, glial nodules, and neuronophagia. No underlying malignancy or general disease impairing immunity mechanisms was discovered.


Subarachnoid haemorrhage.

Subarachnoid haemorrhage.


Subannular aneurysms associated with acute, massive aortic insufficiency.


Subclavian artery aneurysm; sequela of thoracic outlet syndrome.


Subdural empyema. Recent experience in diagnosis and treatment.


Substitution of five essential amino acids by their alpha-keto analogues in the diet of rats.


Subunit molecular weight of human hypoxanthine-guanine phosphoribosyltransferase.


Subtilisin-catalyzed hydrolysis of peptide methyl esters.


Success of reproduction in pikas, Ochotona princeps (Richardson).


Successful surgical treatment for recurrent life-threatening ventricular tachyarrhythmias.


Succinylsulfathiazole crystal forms. I. Preparation, characterization, and interconversion of different crystal forms.


Sudden death and hexachlorophene.

Sudden death and hexachlorophene.


Sudden unexpected death in hemoglobin SC disease.


Sturge-Weber disease with subarachnoid hemorrhage.


Suggestions for treating drug abusers in a family practice.


Sudden, severe aortic regurgitation: reversal of the abnormal hemodynamics by amyl nitrite inhalation.


Sulphur in different types of keratohyalin granules: a quantitative assay by X-ray microanalysis.


Sudden unexpected death in infants in the Oxford Record Linkage area: the mother.


Superhelix density heterogeneity in closed circular intracellular PM2 DNA.


Supercoiled circular DNA in crown-gall inducing Agrobacterium strains.


Supervisor self-concept and self-concept deterioration among psychotherapy trainees.


Supersaturated bile--is it due to a metabolic disorder or to an impaired gallbladder?


Superimposition of thyroid hormone regulation on gonadotropin secretion.


Suppression and enhancement of allografted tumour.


Suppression of cell-mediated immunity in experimental African trypanosomiasis. Adult New Zealand white rabbits were experimentally infected with a parasitic African hemoflagellate, Trypanosoma congolense, and were subsequently tested for in vivo and in vitro aspects of cell-mediated immune function. Chronically infected rabbits were sensitized to mycobacterial protein and skin-tested with purified protein derivative; all infected animals demonstrated much milder skin-test responses to antigen than control groups. Similarly, peripheral blood lymphocyte responses in vitro to purified protein derivative and, as well, to phytohemagglutinin were markedly suppressed. Supernatant fluids of antigen-stimulated lymph node cell cultures from T. congolense-infected rabbits failed to demonstrate migration inhibitory factor activity but did possess normal levels of blastogenic factor activity. An active infection was necessary for demonstration of suppressed immune responses, and components present in infected rabbit serum were apparently not responsible for the observed abnormalities. Suppression of T-lymphocyte subpopulations may well explain the occurrence of numerous immunological aberrations arising during human and animal infections with the African trypanosomes.


Suppression of the secretion of thyroid stimulating hormone by endogenous triiodothyronine and thyroxine: an observation on a patient of chronic thyroiditis treated with corticosteroid.


Supracondylar fractures of the humerus in children. Reasons for unsatisfactory results.


Suppression of prolactin release by a purified porcine PIF preparation and catecholamines infused into a rat hypophysial portal vessel.


Suprahelical arrangements of hydrogen bonds in peptide helices.


Surface markers on hairy cells.

Surface markers on hairy cells.


Surface potential contribution from discrete elements of ventricular wall. A closed chest, postmortem-documented prospective study.


Surfaces and cleansing mechanism of the trachea and bronchi.


Surface polysaccharide from Staphylococcus aureus M that contains taurine, D-aminogalacturonic acid, and D-fucosamine. The surface polysaccharide antigen of Staphylococcus aureus M was isolated, and the component parts were identified. The antigen is composed of taurine, d-aminogalacturonic acid, and d-fucosamine. The capsule is chemically distinct from all previously reported staphylococcal capsules. Taurine and aminogalacturonic acid have not been reported previously in staphylococci.


Surgery of the liver in community hospitals.


Surgical management of colorectal polyps.


Surgical management of duplication of the collecting system.


Surgical management of stag-horn renal calculi.


Surgical procedure for congenital absence of the superior oblique.


Surgical significance of the cremaster muscle in adult indirect inguinal hernia repair.


Surgical treatment of bilateral iliac artery occlusive disease in high-risk patients.


Surgical treatment of congenital dislocation of the hip in children over the age of two years.


Surgical Grand Rounds from the University of Mississippi Medical Center: Renovascular hypertension.


Survey of hospital purchasing.

Survey of hospital purchasing.


Survival of cysts of Echinococcus granulosus after transplant into homologous and heterologous hosts.


Susceptibility of different species of insects to an extract of the venom gland of the wasp Microbracon hebetor (Say).


Suspected aminophylline causes of asthma: three case reports.


Surgical management of the paralyzed orbicularis oculi.


Sweating in the kangaroo: a cooling mechanism during exercise, but not in the heat.


Symposium on comparative toxicology: the relationship between animals and humans.


Sympathetic influences on cardiac rate and contractility during acute stress in humans.


Symptomatology of common imported disease.


Symptomatic metastatic melanoma of spleen.


Symptomatic outcome in schizophrenia.

Symptomatic outcome in schizophrenia.


Syncope in patients with chronic bifascicular block. Significance, causative mechanisms, and clinical implications.


Synovial chondromatosis of the hand. Case report.


Syntheses and conformational studies of poly(N-epsilon-methyl-L-lysine), poly(N-delta-methyl-L-ornithine), poly(N-delta-ethyl-L-ornithine), and their carbobenzoxy derivatives.


Syntheses of amino acids from aliphatic carboxylic acid by glow discharge electrolysis.


Synthesis and conformational study of poly(N delta-carbobenzoxy, N delta-benzyl-L-ornithine) and poly(N delta-benzyl-L-ornithine).


Synthesis and degradation of microvillar protein of kidney in adult rats.


Synthesis and optical studies of L-methionine oligopeptides in solution.


Synthesis and turnover of lysosomal glycoproteins. Relation to the molecular heterogeneity of the lysosomal enzymes.


Synthesis and CNS activity of 3-substituted 7-chloro-5-phenyl-1,3,4-benzotriazepin-2-ones.


Synthesis of (1,6-alpha,alpha'-diaminosuberic acid)oxytocin ('dicarba-oxytocin').


Synthesis of a collagenous basal membrane by rabbit corneal endothelial cells in vitro.


Synthesis of benzoxazino- and naphthoxazinoquinoline derivatives as possible antitumor agents.


Synthesis of blood and cuticular proteins in late pharate adults of the cecropia silkmoth.


Synthesis and biologic examination of some derivatives of 2,2'-anhydro-1-(beta-d-arabinofuranosyl)cytosine hydrochloride (NSC-145668).


Synthesis of bradykinin by fragment condensation on a solid support.


Synthesis of low-frequency noise for use in biological experiments.


Synthesis of coformycin.

Synthesis of coformycin.


Synthesis of peptides containing aminophosphonic acids.


Synthesis of some amino acids, sugars, and peptides in cold plasma abiotic synthesis of some high-molecular-weight proteid-like structures (V).


Synthesis of radio-isotopically labelled phosphatidylethanolamines.


Synthesis of substituted benzthiaxanthones for possible schistosomicidal activity.


Synthesis of some glycodipeptides containing hydroxyamino acids, and their stabilities to acids and bases.


Synthesis of substituted anilino-(3-methoxy-4-(4-arylthiosemicarbazidocarbonylmethyleneoxy))benzylidenes: correlation between anticonvulsant activity and monoamine oxidase inhibitory and antihemolytic properties.


Synthesis of 11 beta-3H-prostaglandin E2.


Synthesis of wax esters for use as possible sperm oil replacements.


Synthesis of the second and fourth components of complement by tissue cultured cell lines.


Synthesis of O-methyl-L-serine and Nalpha-tert-butyloxycarbonyl-O-methyl-L-serine.


Synthesis of the vasoactive intestinal peptide (VIP).


Synthesis of S-alkyl-L-cysteine from pyruvate, ammonia and alkyl-mercaptan by cysteine desulfhydrase of Aerobacter aerogenes.


Synthesis of 6-deoxy-D-galacto-heptose.

Synthesis of 6-deoxy-D-galacto-heptose.


Synthetic analogs of the active sites of iron-sulfur proteins. VI. Spectral and redox characteristics of the tetranuclear clusters (Fe4S4(SR)4).2-.


Synthetic analogs of the active sites of iron-sulfur proteins. VII. Ligand substitution reactions of the tetranuclear clusters (Fe4S4(SR)4)2- and the structure of ((CH3)4N)2(Fe4S4(SC6H5)4).


Synthetic approaches to kasugamine.

Synthetic approaches to kasugamine.


Synthetic heroin-like drugs.

Synthetic heroin-like drugs.


Systemic causes of headache.

Systemic causes of headache.


Syphilis--the placenta and the fetus.

Syphilis--the placenta and the fetus.


Systemic artery to pulmonary vessel fistula.


Systemic reactions to stinging ants.

Systemic reactions to stinging ants.


Systolic pressure amplification in the arteries of normal subjects.


SI units in relation to anaesthesia. A review of the present position.


Talc granulomatosis and angiothrombotic pulmonary hypertension in drug addicts.


Talking point: revitalising Whitley.

Talking point: revitalising Whitley.


Taylor series expansion of delay differential equations--a warning.


Talking point: family feeling.

Talking point: family feeling.


Teaching library skills.

Teaching library skills.


Teaching number conservation.

Teaching number conservation.


Team-patient interaction in chronic hemodialysis units.


Techniques of orthomolecular diagnosis.

Techniques of orthomolecular diagnosis.


Technology and private medicine-a new look.


Telemetry of left ventricular diameter and pressure measurements from unrestrained animals.


Television club for the less able.

Television club for the less able.


Temperature regulation during fever: change of set point or change of gain? A tentative answer from a behavioural study in man. 1. Four subjects were immersed in a stirred water-bath maintained at either 30 or 40 degrees C. The left hand was placed out of the bath in a glove receiving water at a temperature selected by the subject as most pleasurable. Experiments were conducted during the euthermic state and during either spontaneous or induced fever.2. The results of control experiments confirm a previous observation using the same method, that preferred hand skin temperature was a linear function of internal temperature but also indicated an influence by mean skin temperature.3. The general pattern of response during fever was identical to that when fever was absent except that the regulated steady state internal temperature was higher and the slopes of preferred temperature plotted against internal temperature were steeper.4. The results seem to support the concept of a change in set point rather than that of a change in the gain of the thermoregulatory processes during fever.


Temperature effects on resting potential and spike parameters of cat motoneurons.


Technetium counting in rheumatoid arthritis. Evaluation in the small joints of the hand.


Temperature sensitivity of the paw of the cat: a behavioural study. 1. Cats were trained to respond to differences between the temperatures of the floors of two corridors of a modified T-maze for a food reward.2. The cats were able to respond to differences between warm temperatures or differences between cool temperatures in the range of 1 degrees C.3. Both warm and cool discriminations were mediated by receptors located in or near the footpads.4. The paw of the cat thus appears to be more sensitive to temperature changes than was believed previously, and its temperature sensitivity may be comparable to that of the hand of the primate.


Temporal approach to superior oblique surgery.


Temperature-sensitive mutants of adenovirus type 12 defective in viral DNA synthesis. Ten temperature-sensitive (ts) mutants of adenovirus type 12 which produce plaques at 31 but not at 38.5 C have been isolated after mutagenesis with nitrosoguanidine or nitrous acid. The mutants have been classified into six separate complementation groups. DNA-DNA hybridizations have shown that at 38.5 C the ts 401 and 406 mutants of groups B and E, respectively, synthesized less than 10% of the normal level of viral DNA. The two mutants were also defective in the production of late proteins at the nonpermissive temperature, as shown by fluorescent-antibody tests and analysis by sodium dodecyl sulfatepolyacrylamide gel electrophoresis. Genetic recombination between the ts viruses 401 and 406 has been demonstrated; the recombination frequency for the wild-type virus production was 17.7%. Both mutants induced an increase in thymidine kinase activity at 38.5 C. Moreover, the two viral DNA-defective mutants shut off host DNA synthesis at the restrictive temperature. It is striking that at 38.5 C ts virus 401 transformed two to eight times more hamster cells than the wild-type virus, whereas ts virus 406 transformed at a frequency similar to the wild-type virus.


Temporal arteritis.

Temporal arteritis.


Temporal patterns in plasma luteinizing hormone concentration in ovariectomized rats during different times of the day.


Temporal bone findings in the third and fourth pharyngeal pouch (DiGeorge) syndrome.


Temporal patterns of response to ecdysone and juvenile hormone in the epidermis of the tobacco hornworm, Manduca sexta.


Teratogenicity and neonatal toxicity of clindamycin 2-phosphate in laboratory animals.


Test-retest reliability of the self-concept self-appraisal inventory.


Teratologic studies with FD and C red no. 2 in rats and rabbits.


Test-retest reliability of the wechsler battery as a measure of PAS dimensions.


Testicular atrophy from inhalation of ethylene oxide cyclic tetramer.


Testicular involution in short photoperiods inhibited by melatonin.


Testosterone turnover in cancer of the prostate: suppression by gestagens in vitro.


The accuracy of the measurements of weights and tail length in mice.


The "runaway practice".

The "runaway practice".


Tetraparental sheep chimaeras induced by blastomere transplantation. Changes in blood type with age.


The action of chlorpromazine on exploration in pairs of rats.


The action of vitamin C on blood vessels.


The action of diazepam on human skeletal muscle.


The action of 1-tyrosine and arachidonic acid on the experimental hypertension in rat: physiopathogenic deductions.


The activity of pyruvate dehydrogenase in rat brain during postnatal development.


The activation of kallikrein in acute Babesia argentina infections of splenectomised calves.


The activity of various topical griseofulvin preparations and the appearance of oral griseofulvin in the stratum corneum.


The acute toxicity of L-dopa.

The acute toxicity of L-dopa.


The advantages of biplane radiography in angiography of the aortic arch and brachiocephalic vessels.


The additive effects of tranquilizers and dopamine on smooth muscle.


The ageing uterus and its refractoriness to appropiate sex steroid in the development of deciduoma.


The afferent discharge pattern of atrial mechanoreceptors in the cat during sinusoidal stretch of atrial strips in situ. 1. The differences in spike discharge from atrial mechanoreceptors in vivo suggest the existence of different receptor types. To test this possibility, and to see how atrial receptors compare with other mechanoreceptors, their response was studied under comparable stimulus conditions.2. Sinusoidal length changes, with frequencies from 1 to 10 Hz and amplitudes of 1.5-5.0 mm at a given static extension, were imposed in situ on strips of atrial receptor areas of cats.3. The receptor response was evaluated from functional single fibres in terms of number of spikes per stimulus period, average discharge rate, instantaneous spike frequency, and phase angle between forcing function and instantaneous frequency.4. Irrespective of the fibre type, atrial fibres appear to originate from identical mechanoreceptors which sense length at low stimulus frequency and low stimulus amplitudes, but also sense velocity in the high frequency range and with large stimulus amplitudes.5. The difference in the discharge pattern and in the functional behaviour of the atrial fibres in vivo can be explained on the basis of identical receptors.6. The difference in the temporal occurrence of the atrial burst is still open to debate, but probably is related to the site of the receptor.


The ampulla of the vas deferens as a source of spermatozoa in the ejaculate of the vasectomised ram.


The amino-acid sequence of plastocyanin from Sambucus nigra L. (Elder).


The amino acid sequence of plastocyanin from Solanum tuberosum L. (potato). The amino acid sequence of plastocyanin from potato was determined. It consists of a single polypeptide chain of 99 residues, of molecular weight 10332. The sequence was determined by using a Beckman 890c sequencer and by dansyl-Edman analysis of peptides derived from purified CNBr fragments. The sequence shows considerable similarity with that of Chlorella fusca, and also with the C-terminal region of bacterial azurins.


The analgesic activity of alpha-1-acetylmethadol and two of its metabolites in mice.


The analysis of a dose-rate effect found with a mutagenic chemical.


The anatomical precursor of colorectal carcinoma.


The antagonistic effects of aspartic acid on some effects of morphine on rats.


The anomalous rectification and cation selectivity of the membrane of a starfish egg cell.


The antigenic differentiation of seven strains of Mycoplasma hyorhinis by growth-inhibition, metabolism-inhibition, latex-agglutination, and polyacrylamide-gel-electrophoresis tests.


The application of a quantitative estimate of cough frequency to epidemiological surveys.


The application of principles of prevention to the control of communicable diseases in Nigeria.


The application of Bode analysis to skin impedance.


The assessment of disability caused by severe head injury.


The assessment of physiological changes occurring during rehabilitation of lower limb injuries at the Joint Services Medical Rehabilitation Unit.


The association of neoplasms of the colon and rectum with primary malignancies of other sites.


The autoimmune response to male reproductive tissues of rabbits. II. The secondary response as an indicator of cryosensitization to accessory tissue.


The autonomic innervation of the nasal blood vessels of the cat. 1. A study has been made in the anaesthetized cat of the stimulation parameters required to separate the vasodilator and vasoconstrictor responses evoked in the nose by stimulating the cut peripheral end of the Vidian nerve.2. The extent of the vasodilation and vasoconstriction was found to be dependent on the stimulation frequency, but whereas vasodilation reached a maximum at 25 Hz, vasoconstriction occurred at lower frequencies and was maximum between 10 and 15 Hz.3. Atropine, in a dose much greater than that which inhibits nasal secretion, did not abolish the vasodilator responses evoked by Vidian nerve stimulation. This suggests that the Vidian nerve may convey atropine resistant fibres to the nasal vasculature.


The base-pairing specificity in chromatographic systems.


The basicity of anion exchange resins with different functional groups.


The behavior of isotropic pyrolytic carbons under cyclic loading.


The behavior of the XY pair in mammals.

The behavior of the XY pair in mammals.


The binding of nuclear non-histone protein to DNA.


The bioavailability in man of marketed brands of chlorpropamide.


The binding of tetrodotoxin and alpha-bungarotoxin to normal and denervated mammalian muscle. 1. The binding of [(3)H]tetrodotoxin and [(125)I]iodo-alpha-bungarotoxin to innervated and denervated rat diaphragm muscle has been measured.2. A saturable component of tetrodotoxin binding, which was inhibited by saxitoxin, was detected in addition to considerable non-saturable binding. The saturable component had an equilibrium constant of K = 6.1 nM (limits 4.7-7.8 nM) and binding capacity M = 2.5 f-mole/mg wet wt. (limits 2.1-2.8 f-mole/mg).3. If the saturable component consisted of one-to-one binding of tetrodotoxin to sodium channels, the density of sodium channels would be about 21/mum(2) of surface membrane, a figure similar to that found in other excitable membranes.4. After denervation the specific tetrodotoxin binding, as measured by the ratio M/K, fell by a factor of 2.8. This change appeared to be due to a fall in binding capacity rather than a decrease in affinity.5. After denervation the maximum rate of rise of the action potential fell by 27% and became partially resistant to tetrodotoxin. The maximum rate of rise was at first reduced by tetrodotoxin in similar concentrations to those affecting normal muscle, but even large concentrations which completely blocked normal muscle only reduced the maximum rate of rise by a factor of about 2.6. Detubulation with glycerol did not appreciably affect the tetrodotoxin sensitivity of normal or denervated muscle.7. Tetrodotoxin resistance was not observed after denervation of the frog sartorius muscle.8. [(125)I]iodo-alpha-bungarotoxin binding amounted to 3.8 +/- 0.7 f-mole/mg in innervated muscle and 44.5 +/- 2.1 f-mole/mg in denervated muscle. Most of the uptake was inhibitable by (+)-tubocurarine.9. The increase in the labelled bungarotoxin binding is much larger than the specific tetrodotoxin binding of innervated muscle, which renders implausible the possibility that the acetylcholine receptors which appear after denervation are related to the tetrodotoxin resistant-sodium channels.


The birth of a submucous fibroma. An emergency of tropical practice.


The blood supply of the spinal cord. A critical vascular zone in spinal surgery.


The capillary endothelium in the rete mirabile of the swimbladder of the eel (Anguilla anguilla): functional and ultrastructural aspects.


The cardiovascular effects of two new triazine antimalarials, BRL 50216 (Clociguanil) and BRL 6231.


The carotid sinus baroreceptor reflex in the pregnant rabbit. 1. The reflex responses to baroreceptor stimulation have been compared in eight pregnant and eight non-pregnant anaesthetized female rabbits.2. The vascularly isolated, innervated carotid sinus was exposed for 30 sec to a series of non-pulsatile pressures ranging from 30 to 230 mmHg. The contralateral sinus nerve and both aortic nerves were cut. Systemic arterial pressure and heart rate were measured at each sinus pressure.3. The range of arterial pressure change which could be evoked from the isolated innervated sinus was less in the pregnant than in the non-pregnant rabbits. Mean changes were 98 and 61 mmHg respectively. On the other hand changes in heart rate were similar in the two groups (45 and 43 beats/min respectively).4. The smaller blood pressure response in the pregnant animals resulted from a lesser rise in systemic arterial pressure at low levels of sinus pressure. At high sinus pressures the blood pressure fell to a similar level in both groups of animals.5. Pressure on the great vessels by the gravid uterus was not a factor since there was no consistent difference between the responses obtained with the rabbit lying on its back or on its side.6. Mechanisms which might be responsible for the difference found are discussed.


The case of the missing junkies.

The case of the missing junkies.


The chelating properties of a polyisothiouronium ion exchanger.


The changes of serum triiodothyronine, thyroxine and thyroid stimulating hormone in two cases of hypothyroidism with unusual complications.


The chemical preparation of acetylaminoacyl-tRNA.


The children of alcoholics: a neglected problem.


The choice among anterior resection, the pull-through, and abdominoperineal resection of the rectum.


The chronic alcoholic in a small community hospital.


The circular dichroism of three Drosophila virilis satellite DNAs.


The citrate concentration in adult and fetal plasma and in the amniotic fluid of the guinea pig.


The classification of coagulase-negative Micrococcaceae from human and animal sources.


The clinical and biochemical findings in three cases of hypersarcosinemia and one case of transient hypersarcosinuria associated with folic acid deficiency.


The comparative influence of passive (maternal) antibodies in early exposure to JM virus of progeny chicks of dams vaccinated with JM-V leukosis strain and herpesvirus of turkey (HVT).


The clinical features of atrial flutter and their therapeutic implications.


The carpal angle in American populations.


The complex epidemiology of Rhodesian sleeping sickness in Kenya and Uganda. II. Observations in Samia (Kenya).


The comparative metabolism and excretion of HCE, a biodegradable analogue of dieldrin, by vertebrate species.


The conformation of neuroleptic drugs.

The conformation of neuroleptic drugs.


The composition and current use of abortifacients.


The continuing competence of pharmacists.


The conservative surgical treatment of idiopathic aseptic necrosis of the femoral head.


The contradictory impacts of health and environmental regulation on industry.


The contrasting effects on bone histology of vitamin D and of calcium carbonate in the osteomalacia of chronic renal failure.


The contribution of spatial and border interactions to the "Westheimer effect".


The correlation between a positive fern test and the production of small-for-dates babies. A prospective study.


The control of egg maturation by juvenile hormone in the tobacco hornworm moth, Manduca sexta.


The culture of preimplantation rat embryos and the production of allophenic rats.


The current-to-frequency conversion of extraocular motoneurons.


The cyclodesulphurization of thio-compounds. 10. Confirmation of the cyclodesulphurization reaction mechanism of N-homoveratryl-N'-substituted thioureas and their S-alkyl-pseudo derivatives with mercuric chloride.


The cyclodesulphurization of thio-compounds. 9. Cyclization of some N-(1-methyl(or phenyl)-2-(3.4-dimethoxy)-phenyl)-ethylthioamides into the corresponding 3.4-dihydroisoquinoline derivatives with mercuric chloride.


The demonstration of tryptamine in regional perfusates of the dog brain.


The department of research and service in education.


The design of a knee joint implant.

The design of a knee joint implant.


The design, operation and evaluation of a high speed automatic metaphase finder.


The determination of ascorbic acid. A quantitative analysis experiment.


The determination of the dissociation constants of productive and unproductive lysozyme substrate complexes.


The detection and determination of polynuclear aromatic hydrocarbons by luminescence spectrometry utlizing the Shpol'skii effect at 77 K.


The destroyed tuberculous lung.

The destroyed tuberculous lung.


The correlation between disorders of consciousness and the neurological state.