Chemical and ultrastructural studies on the cell walls of the yeastlike and mycelial forms of Histoplasma farciminosum. The cell wall of the yeast form of Histoplasma farciminosum contains 13.2% beta-1,3-glucan, 1.0% galactomannan, and 25.8% chitin, whereas the cell wall of mycelial form has 21.8, 4.5, and 40%, respectively, for the same polymers. Also, the cell wall of the yeast form contains alpha-1,3-glucan (13.5%) and an unidentified polymer (21.5%). Chitin, one of the structural polymers of both yeast and mycelial cell walls, is identified as thin isolated fibers (4 nm wide) or in thick bundles (50 nm wide) of fibers. beta-(1-3)-Glucan is also found as thin isolated fibers indistinguishable from isolated fibers of chitin. Fibers 14 nm wide and resembling alpha-(1-3)-glucan fibers of other fungi are found in the yeast form. The results reported here do not give support to the proposal for a different taxonomic classification.


Chemical constituents of Piper sylvaticum (Roxb) and piper boehmerifolium (Wall).


Chemical dependency: Is pessimism about alcoholics justified?


Chemical equilibria in solutions of bisulfite salts.


Chemical evolution. XXI. The amino acids released on hydrolysis of HCN oligomers.


Chemical modification of erythromycin: synthesis and preliminary bioactivity of selected amides and esters.


Chemical pathology of Krabbe's disease. I. Lipid composition and fatty acid patterns of phosphoglycerides in brain.


Chemical pathology of Krabbe's disease. II. Fatty acid composition of cerebrosides, sulfatides and sphingomyelins in brain.


Chemoimmunotherapy of disseminated malignant melanoma with dimethyl triazeno imidazole carboxamide and bacillus calmette--guérin.


Cheyletiella sp. in the personal environment with notes on the differences between C. parasitivorax Mégnin and C. yasguri Smiley.


Child abuse; hospital combats neglected health crisis.


Child health in Sweden.

Child health in Sweden.


Child performance as a determinant of elderly caretaker behavior.


Childhood and adult schizophrenia: some clinical and experimental comparisons.


Childhood psychopathology and psychotic phenomena in adults.


Children's Hear-More Institute.

Children's Hear-More Institute.


Childhood psychopathology. A natural experiment in etiology.


Chitosan membranes.

Chitosan membranes.


Chloroquine poisoning.

Chloroquine poisoning.


Chloroanisoles as a cause of musty taint in chickens and their microbiological formation from chlorophenols in broiler house litters.


Cholelithiasis. Discussion.

Cholelithiasis. Discussion.


Cholesterol sulfate. I. Occurrence and possible biological function as an amphipathic lipid in the membrane of the human erythrocyte.


Cholinergic drug studies of generalized penicillin epilepsy in the cat.


Choline acetyltransferase and acetylcholinesterase activities in chicken brain hemispheres in vivo and in cell culture.


Chromatographic and electrophoretic behaviour of sulphonamides on thin layers of ion exchangers.


Chondrosarcomas of bones of the hands and feet--a study of 30 cases.


Chromosome evolution in the genus Dipodomys and its taxonomic and phylogenetic implications.


Chronic anorexic and behavioural effects of the fenfluramine metabolite, norfenfluramine: an evaluation of its role in the actions of fenfluramine.


Chronic bronchitis in the dog.

Chronic bronchitis in the dog.


Chronic bronchitis.

Chronic bronchitis.


Chronic carbon monoxide exposure: time course of hemoglobin, heart weight and lactate dehydrogenase isozyme changes.


Chronic gastroduodenitis due to laundry bleach.


Chronic granulomatous disease of childhood with renal involvement.


Chromosome abnormalities from cyclophosphamide therapy in rheumatoid arthritis and progressive systemic sclerosis (scleroderma).


Chronic damage to medium and large arteries following irradiation.


Chronic response of dogs to parathyroid hormone infusion.


Chronic suppurative lung disease in sisters mimicking cystic fibrosis.


Cinefluorographic study of the aortic ball-cage prosthetic valve. Phonocardiographic, hemodynamic and angiographic correlates.


Ciliogenesis in the mouse oviduct. A scanning electron microscope study.


Cineradiographic recognition of papillary muscle calcification.


Circadian control of spermatophore formation in the cricket Teleogryllus commodus Walker.


Circadian and basal interrelationships of plasma cortisol and cations in women.


Circadian rhythmicity of the intestinal transit in rats and its disturbance through experimental hyperthyroidism.


Circulatory effects related to alterations of the ambient environment of the term fetal lamb.


Civilian colonic injuries. Changing concepts of management.


Class experiment in clinical pharmacology with benzilonium bromide, an anticholinergic drug.


Cleavage by beta-glucuronidase of the water-soluble metabolites of digitoxin excreted in the bile of control and spironolactone-pretreated rats.


Clinical applications of the carotid sinus reflex.


Cigarette smoking and strokes.

Cigarette smoking and strokes.


Clinical child psychiatry services on a pediatric-adolescent unit.


Clinical evaluation of indoramin as the sole agent for the treatment of hypertension.


Clinical evaluation of new pulse generator with narrow pulse width for conservation of battery energy.


Clinical evaluation of the hip joint.

Clinical evaluation of the hip joint.


Clinical medicine and research in the Netherlands.


Clinical path conference: Conditions complicating myocardial infarction. Clinical-pathologic correlation in 60 cases.


Clinical pharmacy services: prognostic criteria for selective patient monitoring. II.


Clinical and electromyographic study on latent tetany.


Clinical results of parietal cell vagotomy (highly selective vagotomy) two to four years after operation. In Leeds and Copenhagen 271 patients were treated electively for duodenal ulcer by parietal cell vagotomy without drainage between 1969 and 1972 inclusive, with no operative deaths. 108 patients have been followed up 2-4 years since operation. Gastric stasis necessitating re-operation occurred in only 2 cases. Gastric ulcer developed in 2 cases, and in 3 cases recurrence of the duodenal ulcer was suspected but was unconfirmed at re-operation. Uncontrolled comparison with the results of partial gastrectomy and of vagotomy with drainage, as performed at these two centers, has shown that after parietal cell vagotomy without drainage there is a much lower incidence of dumping, diarrhea and bile vomiting, and, on overall assessment, a greater proportion of perfect or very good results.


Clinical significance of generic inequivalence of three different pharmaceutical preparations of phenytoin.


Clinical utilisation of transfer factor.


Clinical toxicity of chlordiazepoxide and diazepam in relation to serum albumin concentration: a report from the Boston Collaborative Drug Surveillance Program.


Clinical Conference. The foot as a mirror of systemic disease.


Clinically occult inflammatory carcinoma of the breast.


Clofazimine in the treatment of discoid lupus erythematosus.


Closed perineal cryosurgery in prostatic cancer. New probe and technique.


Clinical pharmacology at university medical centers. II. Requirements.


Cloth disruption in a totally cloth covered aortic prosthesis: Case report.


Cluster headache.

Cluster headache.


Coagulation activities in perfused organs: regulation by addition of animal plasmas.


Coarticulation of upper lip protrusion in French.


Cobalt, chromium and nickel content of some vegetable foodstuffs.


Cocaine-induced supersensitivity in the human umbilical artery.


Cocksfoot mild mosaic virus--phleum mottle virus: a comparison.


Codon responses of tRNA-Ala, tRNA-Gly and tRNA-Ser from the posterior part of the silkgland of Bombyx mori L.


Co-ordination of children's services in a semi-rural county district.


Coevolution of Danaid butterflies with their host plants.


Coeliac disease during the teenage period: the value of serial serum folate estimations. A group of teenage coeliac patients has been followed at three monthly intervals in the Outpatient Department to assess their progress and also to monitor their ability to maintain a gluten-free diet. After a follow-up period of four to six years a detailed reassessment was carried out in hospital on 10 patients, only five of whom had persevered with a gluten-free diet. The jejunal mucosal histology of those patients who did not persist with a gluten-free diet remained ;flat' although these patients appeared to have remitted clinically. Those subjects who did persist with a gluten-free regime had a normal or near normal mucosal histology. It was difficult on the basis of clinical, haematological, or biochemical criteria to separate the two groups. The best single assessment of whether these patients were maintaining a gluten-free diet was serial serum folate estimations. It is often extremely difficult to say whether teenage coeliac patients are keeping to their diet unless repeated jejunal biopsies are obtained, and this study suggests that serial serum folate estimations can act as a reasonable criterion of whether subjects are maintaining a gluten-free regime.


Cogan syndrome. The audiological picture.


Cognitive dissonance and the life satisfaction of older adults.


Collagen defects in genetic disorders of connective tissue.


Collection for study of small amounts of vesicular fluid from vesiculobullous skin diseases.


Colchicine inhibition of casein-induced amyloidosis in mice.


Collagen polymorphism: two molecular species in pig intervertebral disc.


College of Family Physicians plans to broaden sphere; requires revenue and GPs.


Color infrared photography of the ocular fundus.


Color-coded antigen for the automated reagin test for syphilis. A low-cost, color-coded antigen was developed for the Automated Reagin Test. A comparative study with 3,000 sera showed a sensitivity somewhat greater than the Rapid Plasma Reagin Card antigen. Samples could be traced back by using a specific color-coded antigen on a given autoanalyzer.


Colorectal carcinogenesis.

Colorectal carcinogenesis.


Colorimetric assay of epinephrine.

Colorimetric assay of epinephrine.


Colorimetric analysis of procaine hydrochloride.


Colorimetric determination of cephradine, a cephalosporin antibiotic.


Colposcopy.

Colposcopy.


Comb variations in the rabbit flea, Cediopsylla simplex (Baker).


Combination rack and roller system for cell culture growth.


Comments on carcinoma of the colon and rectum.


Combination chemotherapy.

Combination chemotherapy.


Committee on maternal welfare.

Committee on maternal welfare.


Community requirements and the modern casualty department.


Community monitoring of air pollution with plants.


Comparative anatomy and general histology of tongues of long-nosed bats (Leptonycteris sanborni and L. nivalis) with reference to infestation of oral mites.


Community screening for coronary heart disease risk factors. Results of screening in 10,000 adult males.


Comparative diagnostic value of endoscopic pancreatography and pancreatic function tests.


Comparative effect of daunomycin and adriamycin on nucleic acid metabolism in leukemic cells in vitro.


Comparative hybridization studies iwth an immunoglobulin light chain mRNA fraction and non-immunoglobulin mRNA of mouse.


Comparative male meiosis in seven species of cotton rats, genus Sigmodon.


Comparative morbidity after vaginal termination with regard to parity and gestational stage. A survey of 3472 patients whose pregnancies were vaginally terminated in the first and second trimester was conducted to determine the influence that parity and gestation might have on morbidity.  The overall comlication rate was 4.33%.  The complication rate was 3.85% for first trimester abortions, and it was 8.3% for midtrimester abortions, a two fold increase over first trimester abortions.  Parity did not have a significant influence on morbidity, although first trimester abortion in parous women was associated with the least complications and the complications rate in early abortion for nonparous women was equivalent to that of  parous midtrimester abortions.


Comparative pharmacokinetics of coumarin anticoagulants. X. Relationship between distribution, elimination, and anticoagulant action of warfarin.


Comparative response of chicks and rats to dietary thyroactive and antihyrotoxic supplements.


Comparative studies on Ancylostoma braziliense and Ancylostoma ceylanicum. 3. Life history in the definitive host.


Comparative studies on Trichophyton verrucosum (Bodin 1902) strains of human and animal origin.


Comparative toxicity, anticholinesterase action and metabolism of methyl parathion and parathion in sunfish and mice.


Comparative--quantitative investigations on brains of feral pigs from the Galapagos Islands and of European domestic pigs.


Comparison among four vehicles and four routes for administering delta9-tetrahydrocannabinol.


Comparison of activity and protein content of ribosomal subunits prepared by four different methods from rabbit reticulocytes.


Comparison of dissolution profiles of tablets and capsules from the USP, Levy, and magnetic basket methods.


Comparison of fluorometric procedures for assay of amphetamine.


Comparison of protein structure in crystals, in lyophilized state, and in solution by laser Raman scattering. 3. Alpha-Lactalbumin.


Comparison of self-ratings of psychiatric patients with ratings made by a psychiatrist.


Comparison of spironolactone tablet dosage forms in healthy humans.


Comparison of the mini-cone biopsy with the punch biopsy and Papanicolaou smear.


Comparison of the effects of stimulation of the sympathetic vasomotor nerves and the adrenal medullary catecholamines on the hind limb blood vessels of the rabbit. 1. The responses to sympathetic nerve stimulation and to the adrenal medullary hormones have been studied in the hind limb vascular beds of the anaesthetized rabbit.2. Simultaneous measurements of femoral arterial blood pressure and of femoral venous blood flow indicate that stimulation of the sympathetic nerves decreases the calculated vascular conductance in both the intact and skinned hind limbs. Evidence is presented to show that these changes are due to vasoconstriction.3. The vasoconstriction in both skin and muscle vascular beds reaches a maximum at frequencies of stimulation around 15 Hz. No vasodilatation is obtained at any frequency of stimulation.4. The rabbit adrenal gland secretes only adrenaline during splanchnic nerve stimulation at frequencies between 3 and 60 Hz. The amounts liberated from both glands over this frequency range are 25-500 ng.kg body wt.(-1) min(-1).5. Intravenous infusions of adrenaline in concentrations similar to those liberated by the adrenal glands during splanchnic nerve stimulation, and of noradrenaline, cause only vasoconstrictor responses in skin and muscle.6. Simultaneous stimulation of the sympathetic nerves to the hind limb and infusion of adrenaline in quantities that could be liberated by splanchnic nerve stimulation at equivalent frequencies shows that the vasoconstrictor effects exerted by the individual components are additive, though the effects produced by the direct sympathetic nerve supply overshadow those produced by the catecholamine.7. The results are discussed in the context of the possible vascular role of the adrenal medullary hormones in the rabbit.


Comparison of the n-terminal amino acid sequences of histone F3 from a mammal, a bird, a shark, an echinoderm, a mollusc and a plant.


Comparison of two generically equivalent carbamazepine preparations.


Comparison of carcinoembryonic antigen (CEA) methodologies.


Comparison of 133Xenon regional studies during spontaneous breathing and bronchospirometry.


Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.


Compartmentation of "endogenous" and newly absorbed vitamin A in the rat.


Competition between carnosine and other peptides for transport by hamster jejunum in vitro.


Competition for ADP between pyruvate kinase and mitochondrial oxidative phosphorylation as a control mechanism in glycolysis.


Competition between skin-sensitizing chemicals in the mouse.


Complement levels of normal cattle.

Complement levels of normal cattle.


Complete failure of eruption of all permanent teeth: an autosomal dominant disorder.


Complete heart block caused by secondary tumors of the heart. Case report and review of literature.


Complexation kinetics of dineopentylmagnesium with l-sparteine.


Complexation of theophylline with sodium benzoate: an NMR study.


Complexity in valinomycin effects on amino acid transport.


Complications of carbenoxolone therapy.

Complications of carbenoxolone therapy. Side effects from carbenoxolone are common and are due to electrolyte disturbance, such as sodium retention and hypokalaemia. They occur particularly in the elderly, who may already be being treated for other illnesses. Eight patients are described with serious side effects from carbenoxolone therapy, some of which were unrecognized for some time because of inadequate follow-up or because clinicians were unfamiliar with them.


Complications of infectious mononucleosis. A fatal case in a 2-year-old child.


Composition and protein quality of sweet lupin seed.


Computer analysis of tracer kinetic data from a human hematopoietic cell line during different phases of growth.


Composition of asteroid bodies.

Composition of asteroid bodies.


Computer program designed to follow fluctuations in microbial populations and its application in a study of Chesapeake Bay microflora. A computer program has been developed which performs cluster analysis of microorganisms using methods of numerical taxonomy. The program is designed to group related strains, identify the groups by reference to known strains, and calculate a hypothetical median organism (HMO) for each group. The HMO serves to condense taxonomic information and provides a tag for each strain cluster. Every strain in a group is compared with the HMO established for that group. A representative strain for the group is obtained by selection of the strain showing highest similarity to the HMO. New data sets can be compared with data sets of previous analyses. Hence, the occurrence of the same taxonomic groups within separate data sets can be determined. Quantitative or qualitative differences in distribution of taxonomic groups within or between data sets can be measured. The output from the computer is a graphical display, using an on-line plotter; thus, the investigator is provided with visual comparison of data sets. Results obtained from a study applying the computer program in an analysis of taxonomic data obtained for 43 bacterial strains isolated from Chesapeake Bay indicate the usefulness of this method of taxonomic analysis in microbial ecology.


Computer-controlled synthesis of tomograms by means of a TV storage tube.


Concentration of androgens in whole testis, seminiferous tubules and interstitial tissue of rats at different stages of development.


Conclusions and recommendations from the National Conference on the Ecology of the Surplus Dog and Cat Problem.


Concentration of testosterone in testis fluid of the rat.


Condensing effect of cholesterol: a physical model.


Conditioned blink reflex and neuronal activity in the auditory cortex of the cat. The present study is concerned with conditioned reflex changes in background and evoked activity of the neuronal population of the auditory cortex (AI) in three waking cats. For the elaboration of a conditioned blink reflex, a series of eight clicks was used as the signal. The unconditional stimulus was rhythmic blowing of air at the eye. During the elaboration of a positive conditioned reflex there was a significant increase in the level of background activity. During conditioned reflex extinction, background activity showed a further increase. When extinguishing inhibition became profound, it was equivalent to sleep, and there was a strong fall in the level of background activity. During the restoration of an extinguished conditioned reflex, background activity fell to the level observed during conditioned reflex extinction, at the stage of consolidation. Application of an acoustic stimulus elicited a general, sometimes a slight increase in the number of spike discharges. Within the range of 300-350 ms - the time of appearance of the evoked response - neuronal activity underwent a reorganization, sometimes with a tendency to phasic variations. Phasic variations of the given population in response to sound were observed at all stages of the study.


Cone-plate viscosimeter and sub-specimen volume.


Conductance increase by adrenaline in guinea pig taenia coli studied with voltage clamp method.


Conformation and optical properties of poly(L-valine) in aqueous solution. "A single extended beta chain".


Conformation of the lithium ion complex of antamanide, a cyclic decapeptide and ion carrier, in the crystalline state.


Conformational change of poly-N epsilon-glutaryl-L-lysine and poly-N epsilon-succinyl-L-lysine in aqueous salt solutions.


Conformational characteristics of polypeptides containing isolated L-proline residues with cis peptide bonds.


Conformational nature of monomeric glucagon.


Conformational stability in dinucleoside phosphate crystals. Semiempirical potential energy calculations for uridylyl-3'-5'-adenosine monophosphate (UpA) and guanylyl-3',5'-cytidine monophosphate (GpC).


Congenital absence of the gallbladder: Review of the literature and report of a new case.


Congenital absence of vas deferens with ipsilateral urinary anomalies.


Congenital arthrogryposis in offspring of sows fed tobacco (Nicotiana tabacum).


Congenital athyroidism in the newborn infant from intra-uterine radioiodine action.


Congenital bronchoesophageal fistula in the adult.


Congenital hemolytic anemia associated with dehydrated erythrocytes and increased potassium loss.


Congenital nephrotic syndrome: a case report.


Congenital porphyria.

Congenital porphyria.


Congenital pulmonary cystic disorders in the neonatal period and early infancy. Three illustrative cases.


Congenital partial gastric antral obstruction, an elusive cause of abdominal pain and vomiting. The patient with partial gastric antral obstruction due to a diaphragm may present with obstructive symptoms at any age in life. Including the four patients presented, there are now 50 reported cases. Since the diagnosis has been unduly delayed in many adults, it is particularly important that those physicians and surgeons caring for infants and children be aware of this entity. If properly treated in infancy and childhood, many years of suffering and debility can be obviated.


Consanguineous marriages and umbilical tetanus in Brazilian populations.


Coniine, a teratogenic principle from Conium maculatum producing congenital malformations in calves.


Consequences of a switch to cook-freeze.


Consequences of total tricuspid valvulectomy without prosthetic replacement in treatment of Pseudomonas endocarditis.


Conservative surgical treatment of carcinoma of the breast.


Conservation of Shannon's redundancy for proteins.


Constancy of a 200 å fiber in human chromatin and chromosomes.


Consumer views: respect is first demand.


Contentment in retirement for the physician.


Contact dermatitis from plants of the caper family, Capparidaceae. Effects on the skin of some plants which yield isothiocyanates.


Continuous recording of multiple parameters during perfusion of human colon.


Contractile response of pial arterioles to norepinephrine. Effects in the mouse.


Contraception--a choice of methods. Family planning. A general overview and new directions in fertility control. This third article in a series called Contraception: a choice of methods discussed the importance fo the pharmacist in having consumer literature and contraceptives openly displayed.  A survey in the Northwestern United States showed that 78% of the 850 respondents displayed contraceptives but only 5% displayed condoms and diaphragms.  Studies have indicated that most patrons purchasing some form of contraception rarely ask the pharmacist for advice.  The pharmacist's professional involvement with contraception can be furthered by: 1) the development of university courses which focus specifically upon available types of contraceptives; 2) establishment of guidelines on marketing procedures  and offering advice to the patron; 3)active involvement with local state and federal agencies in counseling youth and adults who desire access to birth control information; 4) stressing the activity of couseling over that of dispensing; 5)  education of the physician as to the needs of patrons; 6) creation of research programs designed to improve the pharmacists role as an agent for motivating patrons in their acceptance of planned parenthood.  Some of the more promising areas of contraceptive research include prostaglandins, postcoital estrogens, vaginal inserts, monthly injection, male contraception, and copper-surfaced IUDs.


Contraction alkalosis during recovery of cardio-respiratory failure.


Contradictions within the self-concepts of schizophrenics.


Contribution to the inheritance of the Ag groups. A population genetic study.


Contribution to the knowledge of Nigerian medicinal plants.


Control of dimorphism in Phialophora verrucosa.


Control of odors and aetosols from spent grain dryers.


Controlled tests of parbendazole and thiabendazole against natural infections of gastrointestinal helminths of lambs.


Conversations on the social services. Psychiatric aspects.


Conversion of free fatty acids to triglycerides. Determination in obstructive vs hepatocellular jaundice, and cirrhosis.


Conversion of non-convalent interactions in nucleoproteins into covalent bonds: quantitative determination of protein covalently bound to polynucleotides.


Conversion of non-covalent interactions in nucleoproteins into covalent bonds: UV-induced formation of polynucleotide-protein crosslinks in bacteriophage Sd virions.


Conversion of non-covalent interactions in nucleoproteins into covalent bonds: bisulfite-induced formation of polynucleotide-protein crosslinks in MS2 bacteriophage virions.


Cook-freeze food service: staff, equipment, and wastage.


Cooperative monomer binding by polynucleotides. Effect of multiple-loop configurations on formation of triple-stranded complexes.


Copper(II) and zinc(II) binding of optically active dipeptides.


Corneal absorption of fluorometholone in rabbits. A comparative evaluation of corneal drug transport characteristics in anesthetized and unanesthetized rabbits.


Corneal endothelium.

Corneal endothelium.


Coronary blood flow and myocardial reactive hyperemia in the ischemic dog heart.


Coronary heart disease rehabilitation.

Coronary heart disease rehabilitation.


Corrected transposition of the great vessels in a 55-year-old woman; diagnosis by coronary angiography.


Cooperative study of intracranial aneurysms and subarachnoid hemorrhage. Report on a randomized treatment study. II. Objectives and design of randomized aneurysm study.


Cooperative study of intracranial aneurysms and subarachnoid hemorrhage. Report on a randomized treatment study. I. Introduction.


Correlation and prediction of mass transport across membranes. II. Influence of vehicle polarity on flux from solutions and suspensions.


Correlation of prostaglandin E1 receptor binding with evoked uterine contraction: modification by disulfide reduction.


Cooperative study of intracranial aneurysms and subarachnoid hemorrhage. Report on a randomized treatment study. 3. Intracranial surgery.


Correlation of renal medullary prostaglandin content and renal interstitial cell lipid droplets.


Correspondence: Light microscopic and ultrastructural features of an amyloid producing pulmonary carcinoma.


Correlation of the directly observed responses of mesenteric vessles of the rat to nerve stimulation and noradrenaline with the distribution of adrenergic nerves. 1. The effects of nerve stimulation and of the topical application of noradrenaline on arteries, capillaries and veins of the mesentery of the anaesthetized rat were examined by direct observation under a microscope. The distribution of adrenergic nerves to the vessels of the mesentery was studied using the fluorescence histochemical method.2. Principal arteries, small arteries and terminal arterioles were all innervated by a network of adrenergic fibres and they all constricted in response to the stimulation of paravascular nerves and to exogenous noradrenaline. Few adrenergic fibres accompanied the smaller, precapillary arterioles; these vessels did not respond to nerve stimulation, although they were constricted by concentrations of noradrenaline as low as 10(-10) g/ml.3. The capillaries did not respond to nerve stimulation or to applied noradrenaline. All veins were constricted by noradrenaline, but only those veins greater than about 30 mum in internal diameter responded to nerve stimulation.4. At stimulus frequencies greater than 4 Hz the flow of blood through the microvasculature usually ceased, although there was never complete closure of these vessels. The maximum constriction observed in principal arteries was usually between 50 and 70% of the control internal diameter, and in small arteries and terminal arterioles was between 40 and 65% of the control internal diameter.5. It is concluded that the principal arteries and small arteries of the mesenteric vasculature are important in the control of blood flow through this vascular bed during sympathetic stimulation and following topical application of noradrenaline, and that the precapillary arterioles are important vessels determining the rate of blood flow through the capillary bed under resting conditions.


Covalent coupling of aminoacyl-tRNA to modified cellulose as a method of purification of specific tRNAs.


Corrective therapy in the rehabilitation of the quadriplegia patient.


Corticosteroids in human blood. VI. Isolation, characterization and quantitation of sulfate conjugated metabolites of cortisol in human plasma.


Corticosteroid allergy in a patient with systemic lupus erythematosus.


Correlation of immune reactivity and clinical status in cancer.


Coxsackie group B virus and primary myocardial disease in infants and children.


Cranial dermal sinus: value of plain skull x-ray examination and early diagnosis.


Cranial metaphyseal dysplasia. A cause of recurrent bilateral facial palsy.


Craniometaphyseal dysplasia: a case report.


Cranioplasty: a method of prefabricating alloplastic plates.


Creatine kinase activity in the umbilical cord blood of aborted fetuses.


Critical problems in environmental and occupational health.


Critical evaluation of impedance phlebography for the diagnosis of deep vein thrombosis.


Critique of mystical states: a reply.

Critique of mystical states: a reply.


Crohn's disease in heterotopic gastric mucosa in a Meckel's diverticulum.


Cross-correlation functions for a neuronal model. Cross-correlation functions, R(XY)(t,tau), are obtained for a neuron model which is characterized by constant threshold theta, by resetting to resting level after an output, and by membrane potential U(t) which results from linear summation of excitatory postsynaptic potentials h(t). The results show that: (1) Near time lag tau = 0, R(XY)(t,tau) = f(U) [theta-h(tau), t + tau] {h'(tau) + E(U) [u'(t + tau)]} for positive values of this quantity, where f(U)(u,t) is the probability density function of U(t) and E(U) [u'(t + tau)] is the mean value function of U'(t + tau). (2) Minima may appear in R(XY)(t,tau) for a neuron subjected only to excitation. (3) For large tau, R(XY)(t,tau) is given approximately by the convolution of the input autocorrelation function with the functional of point (1). (4) R(XY)(t,tau) is a biased estimator of the shape of h(t), generally over-estimating both its time to peak and its rise time.


Cross-linking of phospholipid neighbors in the erythrocyte membrane.


Crossed renal ectopia.

Crossed renal ectopia.


Crushed chest injury.

Crushed chest injury.


Crosslinking of glycoproteins in human erythrocyte ghosts.


Cryptococcal hepatitis mimicking primary sclerosing cholangitis. A case report.


Crystallographic studies on manganese hemoglobin.


Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI.


Crystallographic study of the interaction of urea with lysozyme.


Culture incubator to simplify manipulation and observation of tissues in vitro.


Cultured calf lens epithelium. I. Methods of cultivation and characteristics of the cultures.


Current concepts of headache. Introduction.


Cultured calf lens epithelium. II. The effect of dexamathasone.


Current methods for diagnosing urologic disease.


Current status of endolymphatic therapy with radionuclides.


Current studies on relation of fat to health.


Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'.


Cutaneous meningiomas--a clinicopathologic study.


Cutaneous vasculitis and hypocomplementaemia.


Cutaneous vasomotor responses to cold pressor stimulation.


Cuticular sclerotization in larval and adult locusts, Schistocerca gregaria.


Cuticular lipids of insects. VI. Cuticular lipids of the grasshoppers Melanoplus sanguinipes and Melanoplus packardii. The cuticular lipids of the grasshoppers Melanoplus sanguinipes and Melanoplus packardii contain 60 and 68% alkanes and 28 and 18% secondary alcohol wax esters, respectively, with lesser amounts of normal and sterol wax esters, triglycerides, alcohols, sterols, and free fatty acids. All the hydrocarbons are saturated, and four types of alkanes are present: n-alkanes, 3-methylalkanes, internally branched monomethylalkanes, and internally branched dimethylalkanes. The principal n-alkanes in both insects are C(29) and C(27), with a range from C(21) to C(33). Trace amounts of 3-methylalkanes of 28, 30, and 32 total carbons are present. The principal internally branched monomethylalkanes are C(32) and C(34), whereas the main dimethylalkane contains 35 carbons. The n-alkanes do not correspond in chain length to the secondary alcohols. The primary alcohols range from C(22) to C(32) in both insects, with C(24) and C(26) predominating. The fatty acids in the triglyceride and free fatty acid fractions range from C(12) to C(24) in M. sanguinipes and from C(12) to C(18) in M. packardii.


Cyclamate and cyclohexylamine: lack of effect on the chromosomes of man and rats in vivo.


Cycle length alternation in supraventricular tachycardia after administration of verapamil.


Cyclic peptides. 8. 13C and 1H nuclear magnetic resonance evidence for slow cis'-trans' rotation in a cyclic tetrapeptide.


Cyclophosphamide--induced cerebral and visceral lesions in rats. Enhancement by endotoxins.


Cyclotetramerization of 2-dimethylamino-4-tert-butylpyrrole. The tetra-tert-butylporphyrins.


Cyrtosomum mega sp. n. (Nematoda: Oxyuroidea) from the lizard, Cyclura carinata.


Cystic adventitial degeneration of the common femoral artery.


Cystic metastasis in the spleen.

Cystic metastasis in the spleen.


Cysticercosis in Ludhiana (Panjab).

Cysticercosis in Ludhiana (Panjab).


Cysts of the nasopharynx.

Cysts of the nasopharynx.


Cytochemical and radioautographic analysis of erythropoiesis at the ultrastructural level.


Cytochrome b-561 as the single heme protein of the bovine adrenal chromaffin granule membrane.


Cytogenetic effects of X-rays and fission neutrons in female mice.


Cytogenetic investigations on leucocytes of cattle intoxicated with heavy metals.


Cytogenetic observations in Culex tarsalis: mitosis and meiosis.


Cytogenetic studies in mycosis fungoides.


CHA chairman's address.

CHA chairman's address.


Cytoplasmic metachromasia in cultured skin fibroblasts from parents of children with cystic fibrosis.


Cytotoxic effects of vanadium on rabbit alveolar macrophages in vitro.


CMA statement offers a personal, moral commitment to every Canadian physician.


CTP synthetase activity in neonatal and adult rat brain.


D-Phenothrin, a promising new pyrethroid for disinsecting aircraft.


Dactylogyrids from North American cyprinids of the genus Nocomis. The bellicus group.


Dane complexes in hepatitis B antigen.

Dane complexes in hepatitis B antigen.


Dantrolene sodium: its effect on extrafusal muscle fibers.


Dapsone in leprosy.

Dapsone in leprosy.


Datagram: Salaries of strict full-time faculty in U.S. medical schools.


Dating a waterlogged coffin.

Dating a waterlogged coffin.


Day hospitals and day centres in an English county.


Damage of nervous system following perinatal hypoxia.


Dead space and blood gases.

Dead space and blood gases.


Deafferentation studies on motor activity in the chick. I. Activity pattern of hindlimbs.


CNS lesions in prolonged disorders of responsiveness,.


Deafferentation studies on motor activity in the chick. II. Activity pattern of wings.


Death during dentistry.

Death during dentistry.


Death caused by fracture of Beall mitral prosthesis. Report of a case.


Decomposition of cannabidiol in chloroform solution.


Defective hydroxyproline metabolism in type II hyperprolinemia.


Defective metabolic clearance of plasma arginine and ornithine in lysinuric protein intolerance.


Defective monocyte chemotactic response in genitourinary carcinoma.


Defective DNA repair in Fanconi's anaemia.


Defects in the sigmoid colon caused by placement of a left hip prosthesis.


Degeneration analysis of the extrinsic nerve elements of the small intestine.


Deaths from drugs. An analysis of drug-induced deaths reported to the Swedish Adverse Drug Reaction Committee during a five-year period (1966-1970).


Daydreaming and the stream of thought.

Daydreaming and the stream of thought.


Deitary iron intakes of adolescents. Relation of sex, race, and sex maturity ratings.


Delayed expression of neonatal sexual differentiation of corticosteroid patterns in rat bile.


Delayed implantation in roe deer (Capreolus capreolus).


Delayed ovulation in rats exposed to continuous light: influence of the level of illumination.


Delayed restoration of abduction in the paralyzed canine larynx.


Delinquency, the Wechsler P greater than V sign, and the I-level system.


Delineation of the dimensions and permeability characteristics of the two major diffusion barriers to passive mucosal uptake in the rabbit intestine. THE RATE OF PASSIVE ABSORPTION INTO THE INTESTINAL MUCOSAL CELL IS DETERMINED BY AT LEAST TWO MAJOR DIFFUSION BARRIERS: an unstirred water layer and the cell membrane. This study defines the morphology and permeability characteristics of these two limiting structures. The unstirred water layer was resolved into two compartments: one behaves like a layer of water overlying the upper villi while the other probably consists of solution between villi. The superficial layer is physiologically most important during uptake of highly permeant compounds and varies in thickness from 115 to 334 mum as the rate of mixing of the bulk mucosal solution is varied. From data derived from a probe molecule whose uptake was limited by the unstirred layer, the effective surface area of this diffusion barrier also was determined to vary with stirring rate and equaled only 2.4 cm(2).100 mg(-1) in the unstirred condition but increased to 11.3 cm(2).100 mg(-1) with vigorous mixing. This latter value, however, was still only 1/170 of the anatomical area of the microvillus membrane. With these values, uptake rates for a number of passively absorbed probe molecules were corrected for unstirred layer resistance, and these data were used to calculate the incremental free energy changes associated with uptake of the -CH(2)- (-258 cal.mol(-1)), -OH (+564), and taurine (+1,463) groups. These studies, then, have defined the thickness and area of the unstirred layer in the intestine and have shown that this barrier is rate-limiting for the mucosal uptake of compounds such as fatty acids and cholesterol; in addition, the lipid membrane of the microvillus surface has been shown to be a relatively polar structure.


Delivery after previous hysterotomy: twelve months experience at a peripheral hospital.


Delta-9-tetrahydrocannabinol and glucose tolerance.


Demography of the Shirishana.

Demography of the Shirishana.


Demonstration and distribution of glycogen in the secondary cartilage of the developing mandibular condyle. Light and electron microscopic study.


Demonstration of enzymic hydrogen transfer from substrate to a flavine.


Demonstration of electrophoretic variation of two aminotransferases in Leishmania.


Demonstration of immune adherence-blocking factors in cell-free tumorous ascites.


Demonstration of radiosensitization of hypoxic cells in solid tumours by metronidazole.


Denaturation mapping of DNA.

Denaturation mapping of DNA.


Density of mucous glands in chronic otitis media.


Dental amalgam--a poison in our mouth?

Dental amalgam--a poison in our mouth?


Dependence of toxicity on molecular structure: group theory analysis.


Deoxyadenylate-rich sequences in sea urchin DNA during early development.


Depolarisation of Onchidium neurone by glycine.


Depressant action of the pineal gland on pituitary luteinizing hormone and prolactin in male hamsters.


Deprivation of amino acids and prenatal brain development in rats.


Dermatoglyphics of childhood psychosis: a family study.


Design lines: university health center provides inpatient, outpatient services.


Design and operation of a mobile pulmonary function laboratory.


Detection and treatment of severe coagulation disturbances in the neonatal period.


Detection of heterozygotes for homocystinuria. Study of sulphur-containing amino acids in plasma and urine after L-methionine loading.


Detection of Australia antigen in blood samples collected on filter paper disks.


Detection of 2,4,6-trinitrotoluene vapours in air by plasma chromatography.


Determinants of physician utilization: a causal analysis.


Determination of amino acid profiles in biological samples by gas chromatography.


Determination and properties of monoglyceride hydrolase in human post-heparin plasma.


Determination of ammonia levels in water and wastewater with an ammonia probe.


Determination of antazoline and diphenhydramine in some pharmaceutical preparations containing ephedrine.


Determination of catheter--manometer system linearity.


Determination of chlordiazepoxide hydrochlor ide (Librium) and its major metabolites in plasma by differential pulse polarography.


Determination of clofibrate in biological fluids by thin-layer and gas-liquid chromatography. A specific and sensitive method is described for the detection of clofibrate in biological fluids. The drug is separated from associated fatty acids by thin-layer chromatography and the methyl ester is quantified by gas-liquid chromatography. Recovery is excellent, and any small losses are corrected with an internal recovery standard. Although more time-consuming than other available techniques, the method offers advantages for accurate studies of clofibrate metabolism.


Determination of diphenylhydantoin by phosphorescence spectrometry.


Determination of isoniazid and metabolites in biological fluids.


Determination of methyldopa in pharmaceutical dosage forms and biological fluids based on oxidation at the tubular carbon electrode.


Determination of nanogram quantities of mercury in sea water.


Determination of membrane potentials in human and Amphiuma red blood cells by means of fluorescent probe. 1. Changes in the fluorescent intensity of the dye, 3,3'-dihexyl-2,2'-oxacarbocyanine, added to suspensions of human and Amphiuma red blood cells were measured in parallel with changes in the membrane potentials of these cells. In these studies the membrane potential was altered in three different ways: by the addition of valinomycin to alter the ratio, P(K)/P(Cl), by a change in the pH of the medium to alter the ratio, Cl(c)/Cl(0), and by the substitution of impermeant anions for Cl(0) again to alter the ratio, Cl(c)/Cl(0). In each case hyperpolarization led to a decrease and depolarization to an increase in fluorescent intensity.2. The change in fluorescence with the addition of valinomycin was dependent on the concentration of K in both the cells and the medium. Changes in fluorescence were not observed when valinomycin was added to suspensions of frozen-thawed, haemoglobin-free ghosts with dye in KCl or NaCl solutions. Such changes were observed with reconstituted ghosts provided that there was a K concentration gradient across the membrane.3. From values of cellular K and the corresponding external K concentrations for which there were no changes in fluorescence with valinomycin, estimations of membrane potentials were made. The potential was -5 to -8 mV for the human red cell and -19 mV for Amphiuma. These values are in good agreement with the potentials estimated from the Cl ratios (-9 mV for human and -17 to -20 mV for Amphiuma) and from those obtained by direct electrical measurements (-15 mV for Amphiuma).4. Fluorescent intensity of the dye in suspensions of human red cells was shown to be a linear function of the log Cl(c)/Cl(0).5. The dye (2.9 x 10(-6)M) increased the inward rate constants for (24)Na (3-4-fold) and (42)K (0.5-2-fold) for human red cells. In addition, the dye was found to be haemolytic (5-6% in 1 hr) at 22 degrees C.6. In contrast, the dye did not alter the rate of (35)SO(4) efflux at 37 degrees C from human red cells previously equilibrated with a Cl-free SO(4) medium.7. The dye was also seen to interact with certain impermeant anions and other compounds, e.g. inhibitors of anion permeability, of interest. These interactions and other limitations of the use of this dye are discussed.


Determination of past trace element uptake in a wild animal by longitudinal analysis of the hair shaft.


Determination of residual urine with 99mTc-DTPA.


Determination of propoxyphene in biological materials.


Determination of ribosomal protein molecular weight distributions from stained dodecyl sulfate gels.


Determination of silicon in streptomycin by atomic absorption.


Determination of the arginine content of proteins by the Sakaguchi procedure.


Determination of the composition and the stability constants of complexes of mercury (II) with amino acids.


Determination of the complete amino acid sequence of bovine neurophysin II.


Determination of the endogenous proteolytic activity in different regions of the visual system of rat brain.


Determination of the total amount of volatile, but slightly soluble, organic materials dissolved in water from oil and oil products.


Determination of zinc and cadmium in environmentally based samples by the radiofrequency spectrometric source.


Developing a health facility medical-moral committee.


Deuteron and sodium-23 NMR studies of lecithin mesophases.


Development of a personality test based on general fund of information.


Development of a reversible vas deferens occlusive device. I. Anatomical size of the human and dog vas deferens.


Development of a reversible vas deferens occlusive device. II. Effect of bilateral and unilateral vasectomy on semen characteristics in the dog.


Development of anticonvulsant osteomalacia in epileptic patients on phenytoin treatment.


Development of p-aminohippurate transport and oxygen consumption in rabbit kidneys.


Development of phenylalanine hydroxylase activity in rat kidney.


Development of strabismus in Siamese cats.


Development of renal response to blood volume expansion in the rat.


Development of the nervous system. A logical approach to neuroanatomy.


Development of Ascaris suum larvae from the third to fourth stage, in vitro.


Developmental study of the renal response to an oral salt load in preterm infants.


Deviant speech characteristics in motor neuron disease.


Dextran-induced anaphylactoid reactions. Report of two cases.


Diabetes and drug abuse.

Diabetes and drug abuse.


Diabetes mellitus among 10,000 adult men. I. Five-year incidence and associated variables.


Diabetes mellitus and primary hypothyroidism.


Development of anaemia in goats fed with Ipomoea carnea.


Diagnosis of pneumoperitoneum in the adult.


Diagnosis in preinvasive lesions of the cervix.


Diagnosis of IgE-mediated reactions to food antigens by radioimmunoassay.


Diagnostic problems of acute abdominal diseases in the aged.


Dial access libraries: Their use and utility.


Dialectical aspects of moral development.


Diaphragm rupture caused by blunt trauma.


Dexamethasone-induced parturition in cattle.


Diarrhea associated with medullary carcinoma of the thyroid. Studies of intestinal function in a patient.


Diagnosis and treatment of tuberculosis in rural Malaysia.


Diastolic heart sound produced by mid-diastolic closure of the mitral valve.


Dibenamine: selective protection against diethylnitrosamine-induced hepatic carcinogenesis but not oral, pharyngeal and esophageal carcinogenesis.


Diet therapy of diabetes. Description of a successful methodologic approach to gaining diet adherence.


Dibromothymoquinone: a new inhibitor of mitochondrial electron transport at the level of ubiquinone.


Diagnostic significance of the Babiński and Rossolimo signs in children up to 4 years of age with the spastic form of cerebral palsy.


Dietary preference and diseases of age.

Dietary preference and diseases of age.


Difetarsone in outpatient treatment of Trichuris trichiura infestation.


Difference in microviscosity induced by different cholesterol levels in the surface membrane lipid layer of normal lymphocytes and malignant lymphoma cells.


Differences in biochemical properties of gamma-aminobutyric acid aminotransferase from synaptosome-enriched and cytoplasmic mitochondria-enriched subcellular fractions of mouse brain.


Differences between murine leukemia virus and murine sarcoma virus: effects of virion age and multiplicity of infection on viral RNA.


Differences in hyaluronidase activities among inbred strains of mice and their possible significance for variations in fertility.


Differences in sphingosine and fatty acid patterns of the major gangliosides of bovine retina.


Differences in molecular structure and cleavage mechanism between pyrimidine-specific RNases from ribosomes of rabbit reticulocytes and from pancreas.


Differences in the excitability of two populations of trigeminal primary afferent central terminals.


Differences in uptake of cadmium in selected organs of normal and alloxan-diabetic rats.


Different recovery rates of the electrophysiological, biochemical and morphological parameters in the cholinergic synapses of the Torpedo electric organ after stimulation.


Differential acceleration by hydrocortisone of the accumulation of epidermal structural proteins in the chick embryonic skin growing in a chemically defined medium.


Differential diagnosis and treatment of depression in the elderly.


Differential binding of tritiated actinomycin to the nuclei of mammalian spermatogenic cells in vivo.


Differential diagnosis of diverticulitis and granulomatous colitis. Exacerbation of granulomatous colitis after sigmoid resection.


Differential effect of metabolic inhibitors on contractile responses of venous smooth muscle to vasoactive simuli.


Differential effects of d-amphetamine on brain acetylcholine in young, adult and geriatric rats.


Differential regulation of a low-molecular-weight protein in oviductal and uterine fluids by ovarian hormones.


Different EEG patterns in patients with quantitative disturbances of consciousness.


Differential utilization of low and high dietary cholesterol by cockerels fed medium-chain triglycerides or corn oil.


Diffusion coefficients of mixed micelles of Triton X-100 and sphingomyelin and of sonicated sphingomyelin liposomes, measured by autocorrelation spectroscopy of Rayleigh scattered light.


Diffuse pulmonary alveolar fibrosis.

Diffuse pulmonary alveolar fibrosis.


Digitalis toxicity. Neurologic manifestations.


Digoxin studies in the elderly.

Digoxin studies in the elderly.


Dilution curve studies in prothrombin complex factors deficiencies and abnormalities.


Dimethylsulfoxide increases the lethality of CCl4 in rats but decreases its hepatotoxicity.


Direct spectrometric determination of the concentration of bilirubins in serum.


Directionally selective light adaptation: a visual consequence of receptor disarray?


Disaccharidase activity in the small intestinal mucosa in cases with acute enteritis.


Discontinuous gel electrophoresis of reduced membrane proteins.


Disease incidence in colostrum deprived calves under commercial conditions and the economic consequences.


Disopyramide phosphate: clinical efficacy of a new oral antiarrhythmic drug.


Dissecting aneurysm after aortic valve replacement.


Disposable organ chamber for perfusion of the ex vivo liver and its use in the treatment of hepatic coma.


Disseminated histoplasmosis successfully treated with amphotericin B. A 61-year-old woman presented with malaise, intermittent fever, weight loss, and epigastric pain. Histoplasma capsulatum was eventually isolated from a liver biopsy and from the bone marrow and the patient was successfully treated with amphotericin B.


Dissolution of digoxin tablets.

Dissolution of digoxin tablets.


Dissociation constant of 60S ribosomal subunit binding to endoplasmic reticulum membranes.


Disseminated intravascular coagulation as a complication of abdominal aortic aneurysm repair. A retrospective review was done of all patients undergoing surgical repair of abdominal aortic aneurysm (AAA) on whom coagulation studies were obtained. Those patients with laboratory documented disseminated intravascular coagulation (DIC) were selected and their clinical records reviewed. This included 7 patients studied in the periods 1964-1965 and January 1971-July 1973. Of these 7 cases, 4 occurred in patients undergoing emergency operation for ruptured aneurysm and 3 were in elective cases. All 7 patients exhibited clinical evidence of abnormal bleeding, while 6 of the 7 progressed rapidly to renal shutdown. The seventh patient recovered spontaneously. Of the 6 patients with full blown clinical and laboratory evidence of DIC, 2 recovered. Both cases received heparin therapy and multiple hemodialyses. A third patient was started on heparin but died at 36 hours in heart failure. All 3 patients receiving heparin showed clinical cessation of abnormal bleeding and disappearance of soluble fibrin monomer complexes within 24 hours of starting therapy. The study suggests a higher incidence of DIC than has previously been appreciated in both the emergency and elective repair of AAA. The prompt recognition and treatment of this complication may reverse the abnormal intravascular clotting, minimize its more serious results and avoid futile and dangerous operative intervention.


Distinctive renal lesion of spirochete-infected brine shrimp. In spirochete-infected Artemia, the renal tubule exhibited a lesion consisting of a group of spirochetes situated in an indentation of the base of the epithelium and involving discontinuity of the basal lamina.


Dissolution of gallstones with bile salts, lecithin, and heparin.


Distribution and metabolism in vivo of 14C-tetrahydrocannabinol in the rat.


Distribution of dieldrin following a single oral dose.


Distribution of dermatophytes causing tinea capitis in Africa.


Distribution of isoniazid inactivators determined in Eskimos and Canadian college students by a urine test.


Distribution of serine hydroxymethyltransferase and glycine transaminase in several areas of the central nervous system of the rat.


Distribution of the receptor sites for Sindbis virus on the surface of chicken and BHK cells. Sindbis virus was adsorbed to chicken cells or to BHK cells, and the distribution of virus over the surface of the cell was examined by electron microscopy of surface replicas. The distribution of virus particles on the cell was used to indicate the position of virus receptors at the cell surface. When purified Sindbis virus was adsorbed at 37 C to cells prefixed with glutaraldehyde, the virus particles were evenly distributed over the surface of most cells. There was a large variability from cell to cell, however, in the number of virus particles adsorbed, and regions with different concentrations of virus particles were sometimes observed on the same cell. The concentration of virus receptors observed varied from 20 to 160/mum(2) of cell surface, and, thus, the total number of virus receptors per chicken cell is on the order of 10(5). When virus was adsorbed to unfixed cells at 4 C, the virus particles were clustered into aggregates varying from a few particles to large crystalline arrays (the latter seen only in chicken cells). These conditions are apparently conducive to virus aggregation, and this, coupled with free lateral diffusion of the virus-receptor complex in the cell membrane at 4 C, leads to the observed clustering.


Disturbances of acid-base equilibrium in infants with congestive heart failure.


Distribution of 125I labelled scorpion (Leiurus quinquestriatus H and E) venom in rat.


Diurnal variations of serum insulin, total glucagon, cortisol, glucose and free fatty acids in normal and diabetic subjects before and after treatment with chlorpropamide.


Divergent influences of Ca2+ on the action of several cardiotonic steroids in isolated heart muscle preparations.


Diverse neurological manifestations of lead encephalopathy.


Diximermis peterseni (Nematoda: Mermithidae): a potential biocontrol agent of Anopheles mosquito larvae.


Does a lecithin-polypeptide association in bile originate from membrane structural subunits?


Dizziness. A logical approach to diagnosis and treatment.


Does systems engineering have a future in health care facilities?


Domesticated rabbits as indicators of California-group arbovirus activity in Wisconsin: experimental studies.


Dominant lethal study of the antiandrogen alpha, alpha, alpha-trifluoro-2-methyl-4'-nitro-m-propionotoluidide: a comparison of statistical methods.


Dopamine, homovanillic acid and 4-hydroxy-3-methoxyphenylglycol in hydrolytic enzyme preparations from Helix pomatia.


Dopaminergic nature of apomorphine-induced pecking in pigeons.


Dope testing in racing animals.

Dope testing in racing animals.


Dosage and choice of parenteral strong analgesics.


Dosage regimens of chloramphenicol in domesticated animals.


Dose-dependent sympathomimetic and cardioinhibitory effects of acrolein and formaldehyde in the anesthetized rat.


Double-helical DNA and RNA circular dichroism. Calculations on base-sugar-phosphateehlix interactions.


Double outlet left ventricle.

Double outlet left ventricle.


Doxycycline concentration in plasma and tissues after intravenous administration. With special reference to acute cholecystitis and appendicitis.


Drowsiness due to chlorpromazine in relation to cigarette smoking. A report from the Boston Collaborative Drug Surveillance Program.


Drinking problems in adopted and nonadopted sons of alcoholics.


Drug abuse.

Drug abuse.


Drug bioavailability information and its utility.


Drug automatism, barbiturate poisoning, and suicide behavior.


Dose- and dosage form-dependent pharmacokinetics of phenacetin and its metabolite in man.


Drug interaction. Discussion.

Drug interaction. Discussion.


Drug information and drug performance. The need for standardization and uniformity.


Drug interactions in vitro.

Drug interactions in vitro.


Drug interactions.

Drug interactions.


Dose-related alterations in metabolism of levodopa: possible mechanism for hypotensive effect.


Drug-induced inhibition of the diuretic response to water loading in partial vasopressin responsive nephrogenic diabetes insipidus.


Drug involvement in automobile driver and pedestrian fatalities.


Drug permeation through membranes. IV. Effect of excipients and various additives on permeation of chlordiazepoxide through polydimethylsiloxane membranes.


Drug-name familiarity and the placebo effect.


Drugs and faith healing.

Drugs and faith healing.


Drugs of the future and the future of drug distribution.


Drug concentrations in the plasma as an index of pharmacologic effect.


Dual photon absorptiometry in lumbar vertebrae. I. Theory and method.


Duct stones present? Transcystic duct operative cholangiography.


Duodenal obstruction caused by cystic masses.


Duodenal obstruction in infants and children.


Dynamic light scattering studies of poly-L-lysine HBr in the presence of added salt.


Dynamic model of ventilatory response to changes in PO2 at the carotid body chemoreceptors.


Dynamic properties of denervated fast and slow twitch muscle of the cat. 1. Isometric and isotonic contractions were recorded from cat flexor digitorum longus (FDL) and soleus muscles denervated for 28-35 days and compared with the responses of contralateral control muscles.2. Isometric twitch time to peak was longer in the denervated muscles than in the controls. Tetanic tension was reduced whether expressed as absolute units, per gram or per unit area. Absolute twitch tensions were reduced less below the control values with a consequent increase of twitch-tetanus ratio. These results agree with earlier reports; but, in contrast, there was no reduction in the relative rate of rise of tension in the isometric tetanus of denervated compared with control FDL. The maximum rate of rise of tension in the twitch was only a little less than that in the fully fused tetanus in the denervated muscles.3. Whole muscle shortening velocity was reduced in the denervated soleus with no change in the number of sarcomeres per fibre. There was a smaller change in FDL muscles. This was the result of an increase in the number of sarcomeres per fibre which followed denervation in FDL, compensating for a decreased velocity of shortening of the sarcomere. Maximum sarcomere shortening velocity was reduced by 30% relative to control values in both muscles.4. Measurements were made of the isometric contractions resulting from pairs of stimuli in an attempt to assess the period of maximal activation in the twitch. Maximum summation occurred when the second stimulus was given close to the time of the peak of the twitch in the denervated muscles.


Dynamic theory of sound-source localization.


Dynamics of the enterohepatic circulation of bile acids. Postprandial serum concentrations of conjugates of cholic acid in health, cholecystectomized patients, and patients with bile acid malabsorption.


Drug-using attitudes and behaviours: their distributions and implications for prevention.


DDAVP in treatment of vasopressin-sensitive diabetes insipidus. In 11 patients with vasopressin-sensitive diabetes insipidus the effectiveness of the vasopressin analogue 1-desamino-8-D-arginine vasopressin (DDAVP) for controlling diabetes insipidus has been compared with that of lysine vasopressin. DDAVP in equivalent intravenous dosage has been found to be at least as potent and to have a more prolonged action, lasting 13-22 hours instead of 1-2 hours. Twice-daily intranasal DDAVP effected satisfactory control in all these patients, without side effects, and all the patients preferred this to their previous treatment. Single daily intramuscular injections of DDAVP were found to offer excellent control for any subject unable to manage intranasal administration.


DNA homology, redundancy and genome size of four Rhizobium bacteriophages.


Duodeno-cutaneous fistulae.

Duodeno-cutaneous fistulae.


DNA levels in differentiating tracheary elements.


DNA synthesis in the liver and kidneys of young rats following a single neonatal carcinogenic dose of dimethylnitrosamine.


D1-trisomy syndrome. Report of a case.

D1-trisomy syndrome. Report of a case.


Eardrum abnormality and the measurement of middle ear function.


Earlier diagnosis of cancer of the colon through colonic endoscopy (colonoscopy).


Early development of ovarian implants on the greater omentum in spayed, hemiovariectomized or hypophysectomized infant and mature rats.


Early diagnosis of airways obstruction.

Early diagnosis of airways obstruction.


Early malignant changes in pleural plaques due to asbestos exposure: a case report.


Early postoperative small bowel obstruction.


Early transit of hospitalized myocardial infarction patients.


Early visual adaptation in goldfish retinal ganglion cells.


Earthworms and coccidian oocysts.

Earthworms and coccidian oocysts.


Eating habits of the dentist and his wife: daily consumption of vitamin E.


Echocardiography.

Echocardiography.


Ectoparasites on rodents in the Nile Valley, upper Egypt.


Editorial: "Nonessential" amino acids.

Editorial: "Nonessential" amino acids.


Editorial: "Whence cometh thou Gehazi".

Editorial: "Whence cometh thou Gehazi".


Editorial: A case for heroin maintenance.


Editorial: A plea for the "naturalistic" study of medicines.


Editorial: A remarkable attempt.

Editorial: A remarkable attempt.


Editorial: Acid perfusion revisited.

Editorial: Acid perfusion revisited.


Editorial: Acute glomerulonephritis and after.


Editorial: Adult respiratory distress syndrome.


Editorial: An analysis of the phase IV price regulations.


Editorial: Anoxic-ischaemic brain injury.


Editorial: Assessing veterinary manpower.


Editorial: Atrial flutter.

Editorial: Atrial flutter.


Editorial: Bangladesh.

Editorial: Bangladesh.


Editorial: Better utilisation of medicines.


Editorial: Azotaemic renal osteodystrophy.


Editorial: Carcinoembryonic antigen.

Editorial: Carcinoembryonic antigen.


Editorial: Can the pill cause birth defects? Potential establishment of a causal relationship between a syndrome of multiple congenital anomalies (vertebral, anal, cardiac, tracheoesophageal, renal, and limb, i.e., "VACTERL") and maternal progesterone/estrogen exposure has been made by  retrospective and prospective studies.  A study providing etiologic evidence between oral contraceptives and birth defects (limb anomalies especially) found only males affected; the proportion of males in another cluster of VACTERL pa tients was also very high (10 out of 15).  It was suggested that if oral contraceptives are teratogenic, it is with people who are predisposed.  Unlike thalidomide, there is no high risk at each exposure but there are a high number of exposures from widespread use.  The importance of eliciting accurate drug exposure histories from mothers is streesed; only 1/3 of the patients who had established exposure to oral contraceptives at a vulnerable embryonic period had this exposure recorded in their charts.  It was concluded that hormonal pregnancy tests should be stopped.


Editorial: Comment on internipple distance.


Editorial: Combinations of antimicrobial drugs: trimethoprim-sulfamethoxazole.


Editorial: Compendia unification becomes a reality.


Editorial: Congenital malformations and antiepileptic drugs.


Editorial: Coroners and the public interest.


Editorial: Data bases for laboratory medicine.


Editorial: Drug spotlight on shock.

Editorial: Drug spotlight on shock.


Editorial: Drugs in the elderly.

Editorial: Drugs in the elderly.


Editorial: Drugs used in hyperuricaemia.


Editorial: Enuresis again.

Editorial: Enuresis again.


Editorial: Extremism in the pursuit of drug abuse prevention.


Editorial: Genetics and dermatologic training.


Editorial: Filtering aspects of lung function.


Editorial: Graduate medical education: moving toward a new status quo.


Editorial: Guidelines on human experimentation.


Editorial: Has coronary surgery come of age?


Editorial: Gram-negative-rod bacteremia.


Editorial: Hypertensive diseases: control by compromise.


Editorial: Immunity to parasitic protozoa and helminths.


Editorial: Hypercapnia in chronic obstructive lung disease--an adaptive response to low-flow oxygen therapy.


Editorial: Infection and diabetes.

Editorial: Infection and diabetes.


Editorial: Ion exchangers and membranes--economic aspects and market strategy.


Editorial: Is gastrin the major regulator of lower esophageal sphincter pressure?


Editorial: Lead poisoning.

Editorial: Lead poisoning.


Editorial: Leukaemia-lymphoma: diagnosis and practical management.


Editorial: Long fiberoptic colonoscopy.

Editorial: Long fiberoptic colonoscopy.


Editorial: Malaria in the United Kingdom.


Editorial: Malignant hypertension.

Editorial: Malignant hypertension.


Editorial: Maternal deaths in Scotland.

Editorial: Maternal deaths in Scotland.


Editorial: Medical rehabilitation.

Editorial: Medical rehabilitation.


Editorial: Medical students: selection techniques.


Editorial: Medical synovectomy.

Editorial: Medical synovectomy.


Editorial: Medicos in ferment.

Editorial: Medicos in ferment.


Editorial: Metabolism of the small-for-gestational-age infant.


Editorial: Methane production in the gut.


Editorial: Methanol poisoning.

Editorial: Methanol poisoning.


Editorial: Migraine clinics.

Editorial: Migraine clinics.


Editorial: Music: a neglected therapy.

Editorial: Music: a neglected therapy.


Editorial: Mirror, mirror on the wall, who needs help the most of all?


Editorial: MFGP (SA).

Editorial: MFGP (SA).


Editorial: National health insurance.

Editorial: National health insurance.


Editorial: Nimbin: life styles and medical services.


Editorial: Non-surgical management of blow-out fracture of the orbital floor.


Editorial: Message from the President of the Association for the Advancement of Medical Instrumentation.


Editorial: Office surgery and the pursuit of excellence.


Editorial: Obsessional slowness.

Editorial: Obsessional slowness.


Editorial: On the present and future state of gynaecological oncology.


Editorial: Paying for research.

Editorial: Paying for research.


Editorial: Perspectives in medical practice and education.


Editorial: Prediction of the respiratory distress syndrome.


Editorial: Prehospital ventricular defibrillation.


Editorial: Premises and promises.

Editorial: Premises and promises.


Editorial: Prevent cardiovascular disease or pay for the consequences.


Editorial: Prevention today, health tomorrow?


Editorial: Private practice and the N.H.S.


Editorial: Psychosomatic influences.

Editorial: Psychosomatic influences.


Editorial: Rehabilitation units: the psychiatrist's role.


Editorial: Reduction of myocardial-infarct size.


Editorial: Resistance among malaria vectors.


Editorial: Rhodes Scholars: 1904-1974.

Editorial: Rhodes Scholars: 1904-1974.


Editorial: Scandinavian standardizations of enzyme determination.


Editorial: Serum creatine phosphokinase.


Editorial: Serum vitamin B 12 levels and vitamin B 12 absorption in normal and physio-pathological conditions in Thailand.


Editorial: Special education--forward trends.


Editorial: Some reflections during a presidential term.


Editorial: Summer preparation for football.


Editorial: Sun, wind, and the skin.

Editorial: Sun, wind, and the skin.


Editorial: Technology in medicine comes of legal age.


Editorial: Symposium on regional blood flow.


Editorial: Tests of growth-hormone production.


Editorial: The "Special Article".

Editorial: The "Special Article".


Editorial: The academic surgical body count.


Editorial: The aetiology of melanoma.

Editorial: The aetiology of melanoma.


Editorial: The anesthesiologist and basic circulatory research.


Editorial: Some observations on pending device legislation.


Editorial: The blue-eyed, red-haired, left-handed pharmacist.


Editorial: The applicability of membrane models to studies of the mechanism of anesthetic action.


Editorial: The clinical significance of parathyroid hormone assay.


Editorial: The future of international conferences.


Editorial: The infection hazard of intensive care.


Editorial: The disc sensitivity test.

Editorial: The disc sensitivity test.


Editorial: The nonoperative treatment of surgical disorders.


Editorial: The phenomenon of resistance development.


Editorial: The pharmacist as a source of drug information.


Editorial: The positive throat culture--what does it mean?


Editorial: The role of the patient.

Editorial: The role of the patient.


Editorial: The special article: political aspects.


Editorial: Tidings of typography.

Editorial: Tidings of typography.


Editorial: Thymic hormones.

Editorial: Thymic hormones.


Editorial: To intervene or not to intervene?


Editorial: To pace or not to pace.

Editorial: To pace or not to pace.


Editorial: The pharmacist and drug product selection.


Editorial: Training of toxicologists and pharmacologists for the chemical industry.


Editorial: Vindication.

Editorial: Vindication.


Editorial: Vitamins and the pill.

Editorial: Vitamins and the pill.


Editorial: Where should I get my training? Trained where?


Editorial: Women in medicine.

Editorial: Women in medicine.


Editorial: Why delay the inevitable?

Editorial: Why delay the inevitable?


Editorial: WDHA-syndrome and gastric secretory inhibitors.


Editorial: Zinc in wound healing.

Editorial: Zinc in wound healing.


Editorial: 1969 pandemic of conjunctivitis.


Effect of acute and chronic ethanol treatment on hepatic triglyceride release from the rat perfused liver.


Effect of adrenoceptor-blocking agents on the renin response to isoproterenol in dogs.


Effect of alkali treatment on single-strand breaks in irradiated dry phi chi 174 RF-DNA.


Effect of anesthesia on rate of N2 washout from body stores.


Effect of amiloride on metabolic alkalosis and hypokalaemia after cardiopulmonary bypass surgery.


Effect of atropine on gastrin and gastric acid response to peptone meal. The action of intravenous atropine on meal-and pentagastrin-induced gastric acid secretion was studied in six duodenal ulcer patients.A test meal of 10% peptone solution adjusted to pH 5.0 was maintained in the stomach at at distention presure of 15 cm H(2)O, and a modification of the intragastric titration method of Fordtran and Walsh was used to measure gastric acid output by monitoring the rate at which a solution of 0.5 M sodium bicarbonate had to be added to keep the pH of the gastric content constant at the initial (pH 5.0) value. Serum gastrin concentrations were measured simultaneously by radioimmunoassy. The dose of 25 mug/kg-h atropine inhibited meal-induced acid secretion by about 70% and that evoked by pentagastrin by about 30%. The serum gastrin response to the test meal was not significantly altered by atropine. We conclude that atropine is a very strong inhibitor of meal-induced gastric acid secretion and does not significantly change serum gastrin response to feeding in duodenal ulcer patients when postprandial gastric acidity (pH 5.0) and intragastric pressure (15 cm H(2)O) are kept constant.


Effect of betamethasone on the production of glucose from propionate by sheep.


Effect of base sequence on the ultraviolet irradiation products of double-stranded polynucleotides containing bromouracil and adenine.


Eelectric communication in fish.

Eelectric communication in fish.


Effect of boundary conditions on the ultrasonic-beam characteristics of circular disks.


Effect of cadmium in vivo on glucose catabolism in normal and alloxan diabetic rats.


Effect of caffeine on intestinal absorption of ergotamine in man.


Effect of chemotherapy in the labelling index of myeloma cells.


Effect of chloramphenicol on reticulocyte delta-aminolaevulinic acid synthetase in rabbits.


Effect of chlorophyll-a in experimental acute pancreatitis.


Effect of cholic acid feeding on bile acid kinetics and neutral fecal steroid excretion in hyperlipoproteinemia (types II and IV).


Effect of chronic dietary nitrates on canine thyroid function.


Effect of amantadine on arterial blood pressure in the rat.


Effect of chronic DDT exposure on pentobarbital tolerance and intolerance in the rat.


Effect of continual drinking of tilorone solution on methylcholanthrene oncogenesis in mice.


Effect of dactylarin of HeLa cells.

Effect of dactylarin of HeLa cells.


Effect of copper loading on various tissue enzymes and brain monoamines in the rat.


Effect of delayed maturity of White Leghorn chickens on subsequent productivity.


Effect of desipramine on rat cortex slices incubated with 3H-dopamine.


Effect of diazepam on mouse whole brain and brain area acetylcholine and choline levels.


Effect of detergents on ADP translocation in mitochondria.


Effect of dicarboxylic acids on inactivation of chicken liver pyruvate carboxylase caused by incubation at 2 degrees C.


Effect of dietary fructose on in vitro and in vivo fatty acid synthesis in the rat.


Effect of dietary selenium and autoxidized lipids on the glutathione peroxidase system of gastrointestinal tract and other tissues in the rat.


Effect of diethylcarbamazine pamoate upon exercise-induced obstruction in asthmatic children.


Effect of different human growth hormone preparations on nitrogen retention in hypopituitary children.


Effect of different fatty acids on glycerolipid synthesis in isolated rat hepatocytes.


Effect of diphenylhydantoin on glucose tolerance in patients with hypoglycemia.


Effect of dopamine on diuresis and its role in forming a renal CR.


Effect of diphenylhydantoin on hepatic drug hydroxylation.


Effect of dose of thyroid hormone on the sensitivity of the McKenzie bioassay.


Effect of electrical vagal stimulation on canine hepatic bile flow.


Effect of drug pretreatment on CBrCl3-induced liver injury.


Effect of ethanol on intestinal absorption of theophylline.


Effect of ethanol on permeability and ion transport in the isolated dog stomach.


Effect of exercise on myocardial infarction in young vs. old male rats: electrocardiograph changes.


Effect of ethanol, acetylsalicylic acid, acetaminophen, and ferrous sulfate on gastric mucosal permeability in man.


Effect of fatty acids and acyl-CoA on the permeability of mitochondrial membranes to monovalent cations.


Effect of food and water deprivation of chickens prior to exposure to Newcastle disease virus.


Effect of gamma-radiation on yield of insulin from beef pancreas glands.


Effect of glucagon on amino acid and nitrogen metabolism in fasting man.


Effect of harvest date and maturity upon free amino acid levels in three varieties of peanuts.


Effect of gonadotrophins on adenylate cyclase of the outer and inner membrane subfractions of rat testis mitochondria.


Effect of hexachlorophene medicated soap on bacterial colonization rates in the new born.


Effect of host decomplementation on homeostasis of antibody production in fowl.


Effect of hypophysectomy on haemodynamic changes induced by administration of oestrone plus vasopressin.


Effect of hypothalamic lesions on maturation and annual cyclicity of the ferret testis.


Effect of increased rat brain tryptophan on 5-hydroxytryptamine and 5-hydroxyindolyl acetic acid in the hypothalamus and other brain regions.


Effect of indomethacin and 7-oxa-13-prostynoic acid on luteinization of transplanted rat ovarian follicles induced by luteinizing hormone and prostaglandin E2.


Effect of interaction between insulin and glucagon on glucose turnover and FFA concentration in normal and depancreatized dogs.


Effect of intragastric administration of alcohol on the ethanol concentrations and osmolality of pancreatic juice, bile, and portal and peripheral blood.


Effect of intrauterine growth retardation on the biochemical maturation of brain synaptosomes in the rat.


Effect of juvenile hormone treatment on caste differentiation in the honeybee, Apis mellifera.


Effect of light on gangliosides from calf retina and photoreceptors.


Effect of lithium on central metabolism of 5-hydroxytryptamine.


Effect of long-term treatment with guanacline or guanethidine on sympathetic function.


Effect of low-residue foods on indomethacin-induced intestinal lesions in rats.


Effect of maintenine on RNA and protein synthesis in cell cultures.


Effect of masker duration and masker level on forward and backward masking.


Effect of mechlorethamine or vincristine sulfate on marrow reticuloendothelial and erythropoietic function in rats.


Effect of methoxyflurane on PAH uptake by rabbit kidney slices.


Effect of methylglyoxal bis(guanylhydrazone) on S-adenosylmethionine decarboxylase in the isolated perfused rat.


Effect of midbrain raphe lesion and of 6-hydroxydopamine on the antinociceptive action of buprenorphine in rats.


Effect of morphine on regional levels of gamma-hydroxybutyrate in mouse brain.


Effect of nicotine on severity of acute myocardial ischemic injury in dogs.


Effect of naphthalene feeding on the cysteine metabolism in rabbits.


Effect of nitrogen on the competitiveness of irradiated Musca domestica.


Effect of one meal on enterohepatic circulation of bile salts.


Effect of oral administration of degraded carrageenan on the induction of gastric ulcers in rats treated with glucocorticoids.


Effect of methylprednisolone on experimental cerebral infarction in the Mongolian gerbil.


Effect of osmotic shrinking and swelling of red cells on whole blood oxygen affinity.


Effect of oxygen breathing on jejunal tissue gas tensions during superior mesenteric arterial occlusion.


Effect of ovine FSH and LH on serum steroids and ovulation in hypophysectomized immature female rats.


Effect of oxytocic agents on blood loss during first trimester suction curettage.


Effect of parathyroid hormone on renal tubular reabsorption of amino acids.


Effect of phencyclidine on hepatic drug metabolism in the rat.


Effect of phenformin on carbohydrate absorption in man.


Effect of phenobarbital and 3-methylcholanthrene administration in vivo and isooctane extraction in vitro on metyrapone binding to reduced cytochrome P-450.


Effect of phenobarbital on the metabolism and serotonin-depleting action of 4-chloro-beta, beta-difluoroamphetamine in rats.


Effect of phentolamine on peripheral venous distensibility in congestive heart failure.


Effect of phospholipases A and C on free amino acid content of the squid axon.


Effect of piribedil and one of its metabolites on the concentration of homovanillic acid in the rat brain.


Effect of prolonged stay at altitude (4000 m) on autonomic balance.


Effect of prostaglandins on the in vitro steroidogenesis in human ovarian tissues. This is a brief report of preliminary findings from in vitro studies of the effect of PGs (prostaglandins) on progesterone formation in human corpora lutea and on the utilization of C21 steroids by the luteal and follicular compartments of the ovary.  Ovaries were obtained from cyclic women undergoing ovariectomies for therapeutic purposes.  The laboratory procedures employed in the study are explained.  Results are tabulated.  PGE2 stimulated progesterone biosynthesis in the corpus luteum as measured by tissue content and by de novo synthesis from acetate-1-14C.  PGE2 also stimulated the biosynthesis of DPS (digitonin-precipitable sterols) from acetate.  These results confirm findings of other researchers.  In 1 of the experiments, PGF2alpha failed to demonstrate stimulation of progesterone biosynthesis in the human corpus luteum as measured by tissue progesterone content after incubation.  Both PGF2alpha and PGE2 showed generally stimulatory effects on the utilization of exogenous labelled progesterone for the formation of androgens and estradiol by the human corpus luteum.  In the follicular tissue, however, PGE2 showed an inhibitory effect on the formation of androgens and progesterone from exogenous labelled pregnenolone.  No significant amounts of estrogens were biosynthesized in these experiments.  These preliminary results must be confirmed by measurement of the endogenous steroidal concentrations in the tissues.


Effect of polyelectrolytes upon the kinetics of ionic reactions. IV. The decomposition of aspirin in aqueous solutions containing polycations.


Effect of pH and citrate ions on adsorption of benzoic acid by sulfamethazine.


Effect of purified and commercial grade tetrachlorophenol on rat embryonal and fetal development.


Effect of pH on the stability of sodium ampicillin solutions.


Effect of reserpine on the adrenal tissue of fasting Nandus (percoid teleost fish).


Effect of retinol and retinoic acid on liver lipids of rats fed different levels of protein.


Effect of several endogenous substances--including porphyrins, hematin, and carbon monoxide--on hepatic clearance of sulfobromophthalein.


Effect of sodium salicylate on the fate of warfarin in the rat.


Effect of synthetic juvenile hormone on ovarian diapause of Culex pipiens mosquitoes.


Effect of sulfachloropyrazine in the drinking water of chickens infected experimentally with fowl cholera.


Effect of some acyl derivatives of amino acids on cell-free protein synthesizing systems from Ehrlich ascites, rat and mouse liver cells.


Effect of temperature and sodium chloride on drag reduction by sodium carboxymethylcellulose and guar gum.


Effect of temperature on sulfate movements across chemically or enzymatically modified membranes of human red blood cells.


Effect of testosterone on the in vitro secretion and metabolism of corticosterone in the rat.


Effect of testosterone propionate on the erythropoietic tissue of three congenital anemias in mice.


Effect of the use of different methods of drying of Digitalis lanata leaves on their quality and glycosidal content.


Effect of tetrahydroisoquinoline derivatives on the adenylate cyclases of the caudate nucleus (dopamine-type) and erythrocyte (beta-type) of the rat.


Effect of thiothixene upon the higher nervous activity in chronic schizophrenics.


Effect of thiourea on rat lung protein synthesis.


Effect of thyroid status on digestive tract fill and flow rate of undigested residues in cattle.


Effect of tissue slicing on rat lung metabolism.


Effect of topical tubercidin on basal cell carcinomas and actinic keratoses.


Effect of vasectomy on guinea pig testes.


Effect of varying the dietary level of calcium on plasma and tissue lipids of rabbits.


Effect of verapamil in obstructive airways disease.


Effect of wall growth on continuous biological oxidation of ferrous iron.


Effect of weight reduction in the rat on epididymal fat-cell size and relative dispersion.


Effect of x-irradiation on the formation of the puparium in the fleshfly, Sarcophaga bullata.


Effect of zinc and cadmium on guinea-pig complement.


Effect of zinc on haemoglobin binding by red blood cell membranes.


Effect of APMO on pulmonary and arterial blood pressure; a comparison with aminorex.


Effect of IUDs, prostaglandins and indomethacin on decidual cell reaction in the rat.


Effect of Ca2+ on coupling of rat liver mitochondria.


Effect of L-asparaginase and hydrocortisone on human lymphocyte transformation and production of a mononuclear leucocyte chemotactic factor in vitro.


Effect of SKF-525-A on the metabolism of (minus)-delta9-tetrahydrocannabinol in the rat brain and liver.


Effective aid for vesicourethral suspension.


Effects of "crowding" on endocrine function and retention of the digenean parasite Microphallus pygmaeus in male and female albino mice.


Effects of a delta9-tetrahydrocannabinol (delta9-THC) metabolite on bone marrow myelopoiesis.


Effects of a new antibacterial sulfonamide (CS-61) on mouse and rat fetuses.


Effects of acute fluid loss on renal contrating function.


Effects of aldrin-transdiol--a metabolite of the insecticide dieldrin--on nerve membrane.


Effects of angiographic contrast media on regional cerebral blood flow and haemodynamics in man.


Effects of castration and testosterone replacement on the number of spermatozoa in the cauda epididymidis of hamsters.


Effects of changing educational requirements on teaching psychiatry.


Effects of changes in temperature and pressure during experimental anaesthesia.


Effects of chronic administration of prostaglandin E1 (PGE1) on arterial blood pressure of unanesthetized hypertensive rats.


Effects of catecholamine-depleting drugs and amphetamine on self-stimulation of brain following various 6-hydroxydopamine treatments.


Effects of chronic sodium depletion on tubular sodium and water reabsorption in the dog.


Effects of colestipol hydrochloride on drug absorption in the rat. I. Aspirin, L-thyroxine, phenobarbital, cortisone, and sulfadiazine.


Effects of degree of thrombocytopenia on thrombocytopoietic response.


Effects of dexamethasone on bone marrow erythropoiesis.


Effects of cyproterone acetate upon urinary aversive cues and accessory sex glands in male albino mice.


Effects of different levels of dietary protein on brain glutamate dehydrogenase and decarboxylase in young albino rats.


Effects of different rates of absorption of two benzodiazepins on subjective and objective parameters. Significance for clinical use and risk of abuse.


Effects of different RNAs and components of the cell-free system on in vitro synthesis of Sindbis viral proteins. Cell-free extracts from Krebs ascites cells and rabbit reticulocytes synthesized a variety of viral-specific proteins when programmed with several different kinds of Sindbis viral RNAs. The RNAs included purified virion RNA (42S) and two species (26S and "33S") of purified intracellular viral messenger RNAs from viral-infected BHK cells. Proteins formed in vitro were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, rate-zonal centrifugation in urea-sucrose gradients, two-dimensional tryptic peptide fingerprints, and immunoprecipitation with rabbit anti-Sindbis virus serum. The only major identifiable protein formed in vitro was viral capsid, but the relative amount of capsid produced was determined by the mRNA, the source of cell-free extract, and the components of the cell-free system. Virion RNA directed synthesis of larger-molecular-weight proteins than did intracellular viral RNAs, and some of this protein was distinct from that formed by the smaller viral RNAs. Indirect evidence is presented for in vitro synthesis of viral envelope proteins.


Effects of early experience on emotional and social reactivity in CBA mice.


Effects of drugs modifying catecholamine synthesis on plasma LH and ovulation in the rat.


Effects of early nutrition on growth of the central nervous system.


Effects of electrical stimulation of the lateral hypothalamus, hippocampus, amygdala and olfactory bulb on unit activity of the lateral habenular nucleus in the rat.


Effects of endogenous parathyroid hormone on calcium, magnesium and phosphate metabolism in rats. II. Alterations in dietary phosphate.


Effects of ethacrynic acid and frusemide on urinary phosphate in the dog.


Effects of fatty acids on the interaction of 1-anilino-8-naphthalenesulfonate with human plasma albumin.


Effects of fructose and glucose infusions on blood acid-base equilibrium in the postoperative period.


Effects of individualised learning procedures on children with specific learning disabilities.


Effects of haemoperfusion through charcoal or XAD-2 resin on an animal model of fulminant liver failure. In a group of dogs in whom fulminant liver failure had been induced, perfusion of blood through activated charcoal resulted in a significantly longer survival than that of a similar group of dogs whose blood was not so treated. An otherwise progressive rise in blood ammonia concentration was halted in the treatment group. In another group of dogs with fulminant liver failure perfusion of blood through the resin Amberlite XAD-2 was associated with a fall in the serum bilirubin concentration and complete clearance from the blood of (14)C-labelled sodium glycocholate. Survival in this group of animals was not significantly prolonged. This was due at least in part to the occurrence of haemorrhage due to thrombocytopenia. Platelets adhere to the resin but do not adhere to the same degree to charcoal coated with a thin layer of polymer.


Effects of high-dose medroxyprogesterone treatment given for endometrial carcinoma on carbohydrate metabolism and liver function. 16 patients with carcinoma of the endometrium were treated with 50-mg medroxyprogesterone im twice daily for 1 year and studied to determine what effect this high dose of progesterone had on carbohydrate metabolism and liver function.  Oral glucose tolerance values (fasting and 2 hour) were significantly elevated (p less than .001) at 12 and 18 months.  Conjugated bilirubin was significantly elevated (p less than .01) at 18 months, aspartate aminotransferase was significantly elevated (p less than .001) at 12 and 18 months.  Insulin values were raised transiently at 3 months.  It is conluded that the changes in carbohydrate and liver function were small, appeared slowly, and included only a few pathologically elevated values; consequently the use of high-dose progestogen treatment for a 1-year period is considered  safe.


Effects of insulin on Schistosomatium douthitti.


Effects of indomethacin on renal inner medullary plasma flow.


Effects of irradiation on the cilia of the Sylvian aqueduct. A scanning electron microscopic investigation.


Effects of isoproterenol on contractile function of the ischemic and anoxic heart.


Effects of ligands and organic phosphates on functional properties of human adult hemoglobin.


Effects of lower body negative pressure on plasma catecholamine, plasma renin activity and the vectorcardiogram.


Effects of nasal stimulation on total respiratory resistance in the rabbit.


Effects of nitrous oxide on volume and pressure of endotracheal tube cuffs.


Effects of nicotine on the shuttlebox behavior of trained guinea pigs.


Effects of o,p'-DDT on the adrenal gland and hepatic microsomal enzyme system in the beagle dog.


Effects of pentagastrin on electrical activity of small intestine of the dog.


Effects of perinatal exposure to methyl mercury on functional brain development and neurochemistry.


Effects of pharmacological doses of iodide on the hyperplastic rat thyroid gland. Roles of intrathyroidal iodide, thyrotropin and thyroglobulin in the Wolff-Chaikoff phenomenon.


Effects of intra-arterially injected contrast media on microvessels in the rat's cecal mesentery.


Effects of phenobarbital and SKF 525A pretreatment, sex, liver injury, and vehicle on delta9-tetrahydrocannabinol toxicity.


Effects of pituitary transplantation and hypothalamic lesions on luteal function in the Mongolian gerbil.


Effects of pre-weaning and post-weaning undernutrition on acetylcholine levels in rat brain.


Effects of proximal gastric vagotomy on intragastric pressure and adaptation in pigs.


Effects of polyvalent cations on stimulus-coupled secretion of (14C)-gamma-aminobutyric acid from isolated brain synaptosomes.


Effects of radiation on cultured BHK cells and their latent "R" particles. An electron microscope study.


Effects of radiotherapy for gynaecological cancer on the intestinal and urinary tracts.


Effects of sleep deprivation on voluntarily controlled reversal rate of ambiguous figures.


Effects of rigid amphetamine analogs on vascular strips: studies of 2-aminotetrahydronaphthalene and 2-aminoindan derivatives.


Effects of some metallic cations on cerebral cortical neurones and their interactions with biogenic amines.


Effects of steady inducer and test duration on threshold.


Effects of supply and withdrawal of fluoride. Experimental studies on growing and adult rabbits. 7. Long-term observations on the reversibility of skeletal fluorosis.


Effects of thiamine and pyridoxine on the composition of fatty acids in Saccharomyces carlsbergensis 4228.


Effects of tetracycline on the dog kidney. A functional and ultrastructural study.


Effects of topically applied 5-fluorouracil in the Syrian hamster.


Effects of thiourea on pulmonary edema, pleural and peritoneal effusions and toxicity in rats pretreated with actinomycin D.


Effects of undernutrition and protein deficiency on glutamate dehydrogenase and decarboxylase in rat brain.


Effects of vinblastine and podophyllin on DBA mouse fetuses.


Effects of vinblastine on the phagolysosome system of proximal tubule cells of rat kidney. Administration of horseradish peroxidase.


Effects of C18, and C21 steroids in vitro maturation of oocytes of the catfish, Heteropneustes fossilis (Bloch).


Effects of warfarin, phenylindanedione, tetrachloropyridinol, and chloro-vitamin K1 on prothrombin synthesis and vitamin K metabolism in normal and warfarin-resistant rats.


Effects of L-dopa administration on the serotonergic system in rat brain: correlation between levels of L-dopa accumulated in the brain and depletion of serotonin and tryptophan.


Effects of 3-acetylpyridine on the central nervous system of the rat, as demonstrated by silver methods.


Effects of 3-amino-1,2,4-triazole on mercury uptake by in vitro human blood samples and by whole rats.


Effects of Quebec Medicare on physician consultation for selected symptoms.


Effects of 5-bromo-2'-deoxyuridine (BUdR) on in vitro colony formation in cultures of mouse bone marrow cells.


Efficient anaesthesia with the EMO ether inhaler.


Efflux of prostaglandin-like smooth-muscle-stimulating activity in the right lymphatic duct in man.


Egg-white sensitivity and atopic eczema.


Ehe incidence of cancer among in-patients with affective disorders.


Eight-channel data set for clinical EEG transmission over dial-up telephone network.


Eimeria acervulina and E. maxima: incidence and anticoccidial drug resistance of isolants in major broiler-producing areas.


Elaboration of conditioned alimentary reflexes having different probabilities of reinforcement in rats with hippocampal lesions. A motor alimentary conditioned reflex was elaborated in hippocampectomized and intact albino rats. Food reinforcement followed 100 percent, 50 percent, 33 percent or 25 percent of conditional stimulus presentations (click from a rotating food box). No differences were found in the rate of conditioned alimentary reflex elaboration between the hippocampectomized and control rats at 100 percent and 50 percent reinforcement, although the time-courses of formation of the conditioned reflex connection differed substantially. With low reinforcement probabilities (33 percent and 25 percent) the operated rats, unlike the intact ones, exhibited no adequate responses throughout the 10 experimental days. The results obtained corroborate an earlier suggestion that the hippocampus is involved in the organization of behavior the reinforcement probability of which is unknown or relatively low.


Elective caesarean section in the mare for the production of gnotobiotic foals.


Electrical recording unit attachment to replace the traditional smoked-drum metal writing point.


Electrical stimulation and drug responses of isolated human umbilical blood vessels.