The determination of vanadium in sea water by hot graphite atomic absorption spectrometry on chitosan after separation from salt.


The development of phosphopyruvate carboxylase and gluconeogenesis in neonatal rats.


The development of the intestinal disaccharidase activities in the fetal and newborn calf.


The development of Brugia pahangi in male Aedes aegypti of "refractory" genotype.


The development of the isthmo-optic nucleus in the duck (Anasplatyrhynchos) I. Changes in cell number and cell size during normal development.


The development of the retino-tectal projection in Xenopus laevis: an autoradiographic and degeneration study.


The diagnosis, control and eradication of bovine brucellosis in Great Britain.


The diagnostic value of radioimmunoassay in clinical medicine.


The differential action of intravenous lidocaine on cerebellar inhibition and cerebellar disfacilitation.


The diffusion of tritiated water across isolated term human amnion.


The differential sensitivity to L-glutamate and L-aspartate of spinal interneurones and Renshaw cells.


The direct determination of cadmium in biological samples by selective volatilization and graphite tube reservoir atomic absorption spectrometry.


The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters. A new plot is described for analysing the results of kinetic experiments in which the Michaelis-Menten equation is obeyed. Observations are plotted as lines in parameter space, instead of points in observation space. With appropriate modifications the plot is applicable to most problems of interest to the enzyme kineticist. It has the following advantages over traditional methods of plotting kinetic results: it is very simple to construct, because it is composed entirely of straight lines and requires no calculation or mathematical tables; the kinetic constants are read off the plot directly, again without calculation; it may be used during the course of an experiment to judge the success of the experiment, and to modify the experimental design; it provides clear and accurate information about the quality of the observations, and identifies aberrant observations; it provides a clear indication of the precision of the kinetic constants; constructed with care, it provides unbiased estimates of the kinetic constants, the same as those provided by a computer program; it may be used to simulate results for illustrative purposes very rapidly and simply.


The disposition of pantothenate in dogs.


The dissociation between endocrine carcinogenesis and tumor antigenicity.


The dissociation of rat liver ribosomes by formamide: extraction of a 5 S RNA-protein complex.


The distribution and ultrastructure of renal lymphatic vessels proliferating in response to kidney injury in the dog.


The distribution in the cell cycle of normal cells and of irradiated tumour cells in mice.


The distribution in the rabbit of choline administered by injection or infusion. 1. The concentration of choline in plasma, erythrocytes, skeletal muscle, heart, lung, liver, small intestine and kidneys and the changes that follow the injection or infusion of choline have been measured in rabbits anaesthetized with pentobarbitone.2. The concentration of choline in the plasma of arterial blood was 11.8 +/- 0.6 n-mole/ml. and in the erythrocytes 28.4 +/- 1.3 n-mole/ml. blood.3. All tissues contained a higher concentration of free choline than did plasma. The values range from 19.1 +/- 2.2 n-mole/g in skeletal muscle to 500 +/- 25 n-mole/g in the kidney.4. In order of their choline concentrations the tissues were intestine (duodenal end) > kidney > intestine (caecal end) > liver > lung > brain > heart > erythrocytes > (blood) > skeletal muscle > plasma, while in order of the contribution to the total body choline they were liver > intestine > skeletal muscle > (blood) > kidney > erythrocytes > lung > brain > plasma > heart. The total free choline determined by these analyses was between 30-40 mumole/kg body weight, about one third being present in the liver.5. The choline content of the small intestine varied along its length. The lowest amount being present in the portion adjoining the caecum.6. Within 1 min of the injection of choline 100 or 300 mumole/kg, 70-90% had left the circulation. The proportionate loss was higher after 100 mumole/kg than after 300 mumole/kg.7. The loss following 300 mumole/kg was increased if that dose were preceded by a dose of 100 mumole/kg 40 min earlier; this suggests some additional disposal mechanism(s) had been activated by the first dose.8. Three minutes after the injection of choline 300 mumole/kg, about 60% was present as free choline in the tissues studied. The order of the concentration increases was kidneys > liver > muscle > lung > small intestine (caecal end) > heart > intestine > small intestine (duodenal end) > brain.9. Forty minutes after the injection of choline 300 mumole/kg, only 11% could be accounted for as free choline. Only the levels in the kidney, liver, muscle and lung were significantly above normal at this time.10. Infusion of choline 0.8 mumole/kg. min or greater produced rises in plasma choline that corresponded to a clearance of 32 ml. plasma/kg. min.11. After the infusion of 300 mumole/kg over a period of 1 hr, raised levels of choline were detected in all tissues assayed, but the amount found accounted for only 14% of the choline administered. The concentrations in the kidney, liver and lung were similar to those found 40 min after the injection of 300 mumole/kg.12. There was no change in the concentration of choline in the erythrocytes after the injection of choline 100 or 300 mumole/kg, nor during the infusion of choline at the rate of 5 mumole/kg. min for 1 hr.13. The plasma volume appeared to be affected by the injection of the large doses of choline; after choline 300 mumole/kg the plasma volume was reduced. No effect on the plasma volume was observed during the infusion of the same dose.


The district general hospital psychiatric unit and the mental hospital--some comparisons.


The distribution of amino acids, Na+ and K+ from surface to centre in incubated slices of mouse brain.


The double radio-isotope derivative technique for the assay of drugs in biological material. I. The determination of maprotiline.


The dynamics of the allomorphic forms of mouse mitochondrial DNA.


The early detection of occupational lung disease.


The ecology of group medical practice in the United States.


The economics of methadone maintenance.

The economics of methadone maintenance.


The effect of a national crisis on patient government.


The effect of age on human third molar and rat molar teeth.


The effect of alimentary hyperlipaemia and primary hypertriglyceridaemia on platelets in man.


The effect of an experimentally induced rise of intraocular pressure in dogs on development of glaucomatous cupping of the optic disc.


The effect of amino acids on the intestinal absorption of immunoglobulins in the neonatal rat.


The effect of anti-inflammatory drugs on phagocytosis and lysosomal enzymes in granulocytic leucocytes.


The effect of atropine and methylatropine on the sweat secretion of unrestrained mice, measured with radioactive saline.


The effect of carbon dioxide in the airways and alveoli on ventilation; a vagal reflex studied in the dog. 1. The inhalation of CO(2) produces a tachypnoea only in the presence of intact vagus nerves; the present study was designed to examine the mechanism of this phenomenon in the dog.2. Closed-chest cardiopulmonary bypass was established in dogs weighing 16-24 kg, anaesthetized with chloralose. When the ;bypass' was established pulmonary blood flow ceased, P(A, CO2) was reduced and the respiratory rate slowed. 3-10% CO(2) in O(2) could then be inhaled without change in the level of P(a, CO2) set at the oxygenator.3. The addition of CO(2) in these concentrations to the inspired oxygen resulted in an increase in respiratory frequency, maximal at the first breath and sustained for the 1 min period of exposure. The increase in respiratory frequency was due to a shortening of expiratory duration. Inspiratory duration did not change. The response was absent after vagotomy.4. Inert gases in O(2), given as a control, had no effect on breathing.5. The effect of raising P(a, CO2) (by increasing the concentration of CO(2) in the gas equilibrating the blood in the oxygenator), was primarily to increase tidal volume.6. The ventilatory effect of inspiring CO(2)/O(2) mixtures was shown to be additive to the effect of raising P(a, CO2).7. These experiments show that an afferent vagal reflex originating from the lungs causes tachypnoea, when a dog, on ;bypass', inhales low concentrations of CO(2) in O(2).


The effect of carticain on mammalian non-myelinated nerve fibres.


The effect of chlorpromazine on visual information processing in normal subjects.


The effect of cholinomimetic drugs on potassium transport in rat cerebral cortex.


The effect of chronic uremia on intestinal mitochondrial activity.


The effect of continuous light or darkness on the rhythm of the mitotic index in the corneal epithelium of the rat.


The effect of apomorphine and dopamine on the arterial blood pressure in anesthetized rat.


The effect of dark rearing and its recovery on synaptic terminals in the visual cortex of rabbits. A quantitative electron microscopic study.


The effect of decreased environmental temperature on pulmonary diffusing capacity.


The effect of exogenous gastrin on the acid sham feeding response in antrum-bulb-resected duodenal ulcer patients.


The effect of frusemide and ethacrynic acid on carbohydrate metabolism.


The effect of glucagon on pentagastrin-induced gastric secretion of sodium, potassium, and calcium in man.


The effect of heparin on the structure and template properties of chromatin.


The effect of glucocorticoid treatment on the release of acid hydrolases from the dearterialized pig liver.


The effect of high femoral osteotomy on osteoarthritis of the hip. An anatomical study of six hip joints.


The effect of glycidate, an inhibitor of glycolate synthesis, on photorespiration and net photosynthesis.


The effect of hypertonic saline on the uptake of tritiated 7,12-dimethylbenz(a)anthracene by the gastric mucosa.


The effect of ionizing radiation on amino acid transport systems in thymocytes.


The effect of irradiation on macrophage migration inhibition.


The effect of isoproterenol sulfate aerosol on the small airways in asymptomatic asthmatic patients.


The effect of isotonic glucose on eating as a function of feeding condition and infusion site.


The effect of lower aliphatic alcohols on the circular dichroism of the complex bilirubin-human serum albumin in aqueous solution.


The effect of nerve growth factor on hindlimb regeneration in Xenopus laevis froglets.


The effect of nigericin and valinomycin on CO2 fixation electron transport and P518 in intact spinach chloroplasts.


The effect of osmolarity on mouse parthenogenesis.


The effect of oxygen administration on mixed venous oxygenation in chronic obstructive pulmonary disease.


The effect of particle size on the absorption of digoxin.


The effect of pentaerythritol tetranitrate pretreatment on experimental coronary occlusion.


The effect of phenobarbital on the metabolism of methinazole in the rat.


The effect of postoperative peritoneal lavage on survival, peritoneal wound healing and adhesion formation following fecal peritonitis: an experimental study in the rat.


The effect of repetitive exercise on ventilatory function in smokers and nonsmokers.


The effect of purified and commercial grade pentachlorophenol on rat embryonal and fetal development.


The effect of pretreatment with dieldrin on certain in vivo parameters of enzyme induction in mice.


The effect of parietal cell vagotomy and pyloroplasty on canine gastric emptying.


The effect of temperature and pressure on Ag-Sn-Hg alloys.


The effect of some liver enzyme inhibitors on the hepatic inactivation of erythropoietin in mice.


The effect of temperature variation on the accuracy of results in a continuous flow analysis system.


The effect of the administration of a homologous antigen on the establishment of Fasciola hepatica in the rabbit.


The effect of the dye neutral red on a strain of Staphylococcus aureus in the presence of sunlight. A strain of Staphylococcus aureus was isolated, the growth of which in the presence of neutral red was inhibited by sunlight. This phenomenon was not shown by any of a number of other strains of the same or different genera.


The effect of tocopherol on the embryonal development. (Preliminary communication).


The effect of trifluralin on the ultrastructure of dividing cells of the root meristem of cotton (Gossypium hirsutum L. "Acala 4-42').


The effect of ultrasound on the potassium content of rat thymocytes in vitro.


The effect of variation in miracidial exposure dose on laboratory infections of Ornithobilharzia turkestanicum in Lymnaea gedrosiana.


The effect of serotonin on regional hemodynamics in the vascular system.


The effect of vasopressin upon the vasculature of the isolated perfused rat kidney. The timed uptake of (131)I-labelled human serum albumin was used as an index of regional perfusion in the isolated rat kidney.1. Arginine vasopressin in doses of 1, 5 and 10 muu./ml. of perfusate decreased papillary perfusion. Total renal perfusion was decreased only by the 5 muu. dose.2. Ornithine-8-vasopressin in doses of 5 and 10 muu./ml. of perfusate decreased papillary perfusion. Total renal perfusion was decreased only by the 10 muu. dose.3. When the relative viscosity of the perfusate was increased to a value of 2.0 from the control value of 1.7, both papillary perfusion and total renal perfusion were reduced.4. Arginine vasopressin further reduced papillary flow in kidneys perfused with high viscosity artificial plasma.


The effect of zinc deficiency on the timing of deoxyribonucleic acid synthesis in regenerating rat liver.


The effectiveness of lithium in affective and schizo-affective psychoses.


The effect of triethyl tin intoxication at the early stage of extrauterine life on cerebral myelination.


The effect of 4-(1-naphthylvinyl)-pyridine (NVP), a choline acetylase inhibitor, on autonomically innervated tissues of the rat.


The effects of a number of hormones on myocardial cell free protein biosynthesising systems and on the uptake of 14C-phenylalanine into protein in the perfused heart system.


The effect of tricyclic antidepressants on apomorphine-induced hypothermia in the mouse.


The effects of amines on the esterase activities of thrombin and thrombokinase and on several clotting tests.


The effects of civil war on the health of a rural community in Bangladesh.


The effects of cortisone acetate on stomach evacuation and the absorption of 125I-labelled globulins in young rats. 1. After short exposure (3-5 hr) to I.P. cortisone acetate (5 mg), the reduced transmission of labelled globulin to the circulation in 14-day-old rats is due to the slow release of the oral dose from the stomach. The ability of the small intestine to absorb and transmit globulin to the circulation is comparable in control and experimental animals.2. About 26 hr after cortisone acetate treatment (5 mg), the greatly reduced absorption of labelled globulin from oral doses administered to rats aged 15 days is due to the combined effects of the slower release of the dose from the stomach and to changes which have occurred in the small intestine.3. About 50 hr after the administration of 5 mg cortisone acetate the effect on the rate of stomach evacuation is minimal in rats aged 16 days. When labelled globulin is introduced directly into the duodenum of these animals virtually no absorption occurs.4. The results obtained from the experiments in which labelled globulin was injected into the duodenum support the contention that the proximal half of the small intestine is an important site for macromolecular transport.


The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results.


The effects of d-amphetamine on the inter-response times of rats and guinea-pigs on a modified Sidman discriminated avoidance schedule.


The effects of hornet venom sac extract on the electrical activity of the cat brain.


The effects of morality and prior experience on helping by schizophrenics.


The effects of morphine, etorphine and sinomenine on the chemical sensitivity and synaptic responses of Renshaw cells and other spinal neurones in the rat.


The effects of music therapy on a group of institutionalised mentally retarded boys.


The effects of ouabain on atrioventricular junctional automaticity and conductivity studied in the dog.


The effects of restricted energy feeding during the growing period on the reproductive performance of turkey breeder females.


The effects of role exchange.

The effects of role exchange.


The effects of testosterone administered neonatally on the incorporation of 3H-leucine into protein and 3H-thymidine into dna in the ventral prostate of rat.


The effects of various naturally occurring cannabinoids on hypotonic-hyperthermic lysis of rat erythrocytes.


The efficacy of therapeutic interventions in social work: a critical re-evaluation.


The effects of scopolamine on performance on a geometric progressive ratio schedule.


The electrical properties of phospholipid bilayer langmuir films.


The emergence of inhibition in the chick embryo spinal cord.


The energy crisis in surgical patients.

The energy crisis in surgical patients.


The energy requirements of obesity.

The energy requirements of obesity.


The epidemiology and control of measles.


The enhancement of maximal bilirubin excretion with taurocholate-induced increments in bile flow.


The epidemiology and natural history of measles in Denmark.


The effects of nicotine on the coronary microcirculation in the cat heart.


The epizootiology of two pathogens of the coconut palm rhinoceros beetle.


The equilibrium constant of the phosphoglyceromutase reaction. The equilibrium constant of the phosphoglyceromutase reaction was determined over a range of pH (5.4-7.9), in solutions of different ionic strength (0.06-0.3) and in the presence of Mg(2+), at 30 degrees C and at 20 degrees C. The values obtained (8.65-11.65) differ substantially from previously published values. The third acid dissociation constants were redetermined for 2- and 3-phosphoglycerate, and in contrast with previous reports the pK values (7.03 and 6.97 respectively at zero ionic strength) were closely similar. The Mg(2+)-binding constants were measured spectrophotometrically and the values, 286mm(-1) and 255mm(-1) for 2- and 3-phosphoglycerate at pH7 and ionic strength 0.02, were also very similar. From the relative lack of effect of temperature, pH and ionic strength it is concluded that the equilibrium constant differs from unity largely because of entropic factors. At low ionic strength, in the neutral region, the pH-dependence can be attributed to the small difference in the acid dissociation constants, but the difference in dissociation constants does not explain the pH-dependence in the acid region or at high ionic strength. Within physiological ranges of pH, Mg(2+) concentration and ionic strength there will be little variation in equilibrium constant.


The epidemiology of primary biliary cirrhosis: a survey of mortality in England and Wales. Primary biliary cirrhosis is a rare disease in the general population. Estimates of its true incidence are difficult but since survival time is unaffected by treatment, mortality may reflect important regional and other variations. One hundred and sixty-five death certificates collected in England and Wales over the five-year period 1967-1971 were inspected and confirmed an overwhelming predilection for females. Deaths rose sharply at ages 50-54 in the latter with a peak of 4.1 million(-1) year(-1), with perhaps a secondary peak at ages 70-74. No relation of mortality with climate, altitude, soil type, annual temperature range, or occupation was found, although outside the UK a broad correlation exists with total cirrhosis deaths. There was a suggestive excess of deaths among married women. The greater frequency of deaths in the London area, a rise in mortality from country to urban areas, a fall-off in deaths from primary biliary cirrhosis in old age, and predominance for social class I suggest a simple relationship with standards of medical care or diagnosis. An ;epidemic' of deaths in 1971 is attributed to greater availability of the mitochondrial antibody test in the regions. The importance of familial primary biliary cirrhosis and various models of pathogenesis are discussed. Both constitutional and environmental factors producing the disease must be widely distributed in the population of this country.


The estrous cycle, reproduction, growth, and development of temperature regulation in the pygmy mouse, Baiomys taylori.


The evaluation of a competent ileocolonic anastomosis.


The evaluation of depressive symptomatology. A triadic approach.


The examination of inks on documents.

The examination of inks on documents.


The experience of open heart surgery. IV. Assessment of disorientation and dysphoria following cardiac surgery.


The exchange and maximal net flux of glucose across the human erythrocyte. II. The effect of two sulphydryl enzyme inhibitors, chlormerodrin and p-chloromercuribenzene sulfonic acid.


The experimental M.D. program for Ph.D.s: an evaluation at the three-year mark.


The eyes' dual function. II.

The eyes' dual function. II.


The facio-scapulo-limb (or the facioscapulohumeral) type of muscular dystrophy. Clinical and genetic study of 200 cases.


The fate of eggs and larvae of Ascaridia galli in earthworms.


The fatty acid composition of edible oils and fats. A beginning glc experiment.


The fate of phenolics in wastewater--determination by direct-injection GLC and Warburg respirometry.


The fate of elderly amputees.

The fate of elderly amputees.


The features and course of bile vomiting following gastric surgery.


The fibrinolytic system and postoperative thrombosis following operation of rectal carcinoma. A preliminary report.


The fights may be harder to duck in the future.


The fine structure and function of the mechanically injured renal lymphatic capillary.


The fine structural localization of glutamate decarboxylase in synaptic terminals of rodent cerebellum.


The first decade of pediatric surgical training in India.


The fluorimetric determination of sulphide with thiamine.


The folate conjugase activity of the intestinal mucosa in celiac disease.


The formation of the triple helix in a mixed solution of (Pro-Pro-Gly)n and (Pro-Pro-Gly)n'. A model of molecular size recognition.


The freezing lesion. II. Potassium transport within nerve terminals isolated from epileptogenic foci.


The function of a department of community medicine.


The fifth Arthur C. Beall, Jr., M.D., commemorative lecture: regulatory standards and the voluntary sector.


The functional compartmentation of mitochondrial hexokinase.


The gastroscopic diagnosis of gastritis with particular reference to mucosal reddening and mucus covering.


The fungous flora of the sauna and the influence of certain disinfectants.


The genus Eutrombicula in Venezuela (Acarina: Trombiculidae).


The genus Mesolaelaps (Laelapidae: Mesolaelapinae, n. subfam.) with descriptions of two new species from New Guinea.


The geographic pathology of bowel cancer.


The formation of manipulative activities on the example of writing in children with congenital right- and leftsided hemiplegia.


The hairs in the syndrome of Netherton and in a peculiar form of ectodermal dysplasia. A comparative study of the hairs in two inherited hair anomalies.


The half-cystines of bovine kappa-casein.


The half-life of acetylcholinesterase in mature rat brain.


The health of Nigerian children of school age (6-15 years). I. Design of the study, general appearance, heights and weights, nutritional status and haematalogical findings.


The health of Nigerian children of school age (6-15 years). II. Parasitic and infective conditions, the special senses, physical abnormalities.


The health of Nigerian children of school age (6-15 years). 3. The environmental determinants of the health of the children: general discussion and recommendations.


The heart and pulmonary vasculature of the llama (Lama glama).


The hemolytic activity of some trialkyltin and triphenyltin compounds.


The hepatic artery in cirrhosis: An angiographic pathophysiologic correlation.


The hierarchical structure of metabolic networks and the construction of efficient metabolic simulators.


The hexose-proton symport system of Chlorella vulgaris. Specificity, stoichiometry and energetics of sugar-induced proton uptake.


The home behaviour of schizophrenic patients living in the community and attending a day centre.


The hypercalcaemic response to parathyroid hormone in Japanese quail.


The identification of menstrual blood--the immunoelectrophoretic characterisation of soluble fibrinogen from menstrual bloodstain extracts.


The hypotensive effect of prostaglandin E1 on hypertensive cases of various types.


The impact of labeling on rejection of the mentally ill: an experimental study.


The impairment of thermoregulation by trauma during the first days of life of the rabbit.


The importance of age to conservative opinions: a multivariate analysis.


The importance of molecular weight of inorganic polyphosphates for their interaction with deoxyribonucleoprotein of animal tissues.


The importance of muscle reconstruction in primary and secondary cleft lip repair.


The importance of stable isotope labelled drugs in clinical pharmacology: with illustrations from studies on the disposition of propranolol and nortriptyline in man.


The in vitro estimation of transfer factor.


The impulse-blocking concentrations of anesthetics, alcohols, anticonvulsants, barbiturates, and narcotics on phrenic and sciatic nerves.


The in vitro and in vivo effect of chemotherapeutic agents on the Marek's disease herpesvirus of chickens.


The in vivo localization of high-affinity phlorizin receptors to the brush border surface of the proximal tubule in dog kidney.


The increased solubilization of thymus and spleen chromatin from irradiated mice by low deoxycholate concentrations.


The induction of afibrinogenemia by Echis colorata snake bite.


The inefficiency of gastric acid secretion.


The induction of delayed hypersensitivity by macrophage-associated antigen. The role of macrophage cytophilic antibody.


The infant in the black culture. Some high-risk factors and suggestions for intervention and prevention.


The infant in Mexican-American culture.

The infant in Mexican-American culture.


The importance and relevance of studies of the pial microcirculation.


The influence of age on the activity of acetylsalicylic acid-esterase and protein-salicylate binding.


The influence of age on the protein concentration in serum, liver and kidney of rats determined by various methods.


The influence of agricultural development on the nutritional status of homeland populations.


The influence of beta-indoleacetic acid and gibberellin on the template activity of the chromatin of wheat coleoptiles of different ages.


The influence of cyproheptadine and of D-lysergamide on the rise in temperature induced by intracerebroventricular 5-hydroxytryptamine, noradrenaline and dopamine in conscious rabbits.


The influence of enzyme detergent on skin reactions to beryllium.


The influence of fibrin formation on the transplantability of murine tumour cells: implications for the mechanism of the Révész effect. Experiments were undertaken to test a new hypothesis for the mechanism underlying the Révész effect. The hypothesis proposes that lethally irradiated (LI) tumour cells enhance the take probability of a small number of transplanted viable (V) tumour cells mixed with them by exerting a thromboplastic effect at the site of injection; local fibrin formation prevents emigration of V cells from the site or secures their survival there. The evidence presented to support this hypothesis is as follows: in the case of 3 isogeneically transplanted tumours, admixed particulate brain extract simulated the effect of LI cells in increasing the take probability of V cells; brain extract simulated the effect of LI cells in greatly delaying the disappearance of (125)IUdR-labelled viable carcinoma cells from the injection site; V cells acquired a raised take probability by their incorporation in fibrin clots; it was confirmed that admixed erythrocytes increased the take probability of V cells; using a newly devised microscopical test for detection of the thromboplastic activity of individual cells, it was found that cell death was almost always required for the display of such activity; lymphocytes and bone marrow cells, ineffective in enhancing the take of V cells, were almost totally devoid of thromboplastic activity. Possible explanations are given for failure of a fibrinogen depleting agent, ancrod (Arvin) to inhibit the Révész effect when administered to recipients. It is concluded that the evidence strongly supports the hypothesis presented whilst seriously weakening the long-standing theories that admixed LI cells act by provision of nutrients or by local quenching of postulated immune reactivity.


The influence of height on the decline in ventilatory function.


The influence of specific environmental parameters on the circadian rhythms of chickens.


The influence of ligands on the fluorescence of the complex between 8-anilino-1-naphthalene sulfonate and pyruvate kinase of Neurospora.


The influence of pH, temperature, and calcium on platelet aggregation: maintenance of environmental pH and platelet function for in vitro studies in plasma stored at 37 degrees C.


The influence of surgery, time of day, blood volume reduction and anaesthetics on plasma prolactin in ovariectomized rats.


The influence of the number of cycles upon the visual contrast threshold for spatial sine wave patterns.


The influence of the extracellular counter-ion on the sodium-dependent, ouabain-uninhibited sodium efflux from human erythrocytes.


The influence of the surgical technique used for vasectomy on testis function in rats.


The influence of vitamin and magnesium limitations on fatty-acid fingerprints of chemostat grown Streptococcus sp. SS.


The influence of FSH and FSH plus LH on steroidogenic enzymes in the immature mouse ovary.


The inner and outer world.

The inner and outer world.


The influence of beta-amylase and beta-glucuronidase on the fertility of frozen bull semen.


The interaction of beta-cyclodextrin with dinucleoside phosphates.


The interaction of normal lymphocytes and cells from lymphoid cell lines (LCL). V. Cytotoxic properties of activated lymphocytes.


The interdependence of behavior and the psychosomatic symptom.


The interaction of normal lymphocytes and cells from lymphoid cell lines. VI. Line-directed cytotoxic specificity of lymphocytes activated by autochthonous or allogeneic LCL cells.


The interdependence of carpal articulation chains.


The interdependency of cerebral functional and metabolic effects following massive doses of thiopental in the dog.


The internal jugular-subclavian venous reflux test.


The internal cerebral vein: normal and pathological variations in position and configuration.


The interrelation between DNA synthesis and various DNA polymerase activities in synchronized HeLa cells.


The interrelationships between bone mineral at different skeletal sites in male and female cadavera.


The intra-uterine device in Soweto and other townships.


The intestinal unstirred layer: its surface area and effect on active transport kinetics.


The investigation and management of headache.


The intravenous urogram in acute renal failure.


The isolation and properties of phenylalanine hydroxylase from human liver. Phenylalanine hydroxylase was prepared from human foetal liver and purified 800-fold; it appeared to be essentially pure. The phenylalanine hydroxylase activity of the liver was confined to a single protein of mol.wt. approx. 108000, but omission of a preliminary filtration step resulted in partial conversion into a second enzymically active protein of mol.wt. approx. 250000. Human adult and full-term infant liver also contained a single phenylalanine hydroxylase with molecular weights and kinetic parameters the same as those of the foetal enzyme; foetal, newborn and adult phenylalanine hydroxylase are probably identical. The K(m) values for phenylalanine and cofactor were respectively one-quarter and twice those found for rat liver phenylalanine hydroxylase. As with the rat enzyme, human phenylalanine hydroxylase acted also on p-fluorophenylalanine, which was inhibitory at high concentrations, and p-chlorophenylalanine acted as an inhibitor competing with phenylalanine. Iron-chelating and copper-chelating agents inhibited human phenylalanine hydroxylase. Thiol-binding reagents inhibited the enzyme but, as with the rat enzyme, phenylalanine both stabilized the human enzyme and offered some protection against these inhibitors. It is hoped that isolation of the normal enzyme will further the study of phenylketonuria.


The isolation and properties of phenylalanine hydroxylase from rat liver. Phenylalanine hydroxylase was prepared from rat liver and purified 200-fold to about 90% purity. All the enzymic activity of the liver appeared in a single protein of mol.wt. approx. 110000, but omission of dithiothreitol and of a preliminary filtration step to remove lipids resulted in partial conversion into a second enzymically active protein of mol.wt. approx. 250000. The K(m) and V(max.) values of the enzyme for phenylalanine, p-fluorophenylalanine and dimethyltetrahydropterin were measured; p-chlorophenylalanine inhibited the enzyme by competing with phenylalanine. Disc gel electrophoresis at pH7.2 showed a single protein band containing all the enzymic activity, but at pH8.7 the enzyme dissociated into two inactive fragments of similar but not identical molecular weight. The molecule of phenylalanine hydroxylase contained two atoms of iron, one atom of copper and one molecule of FAD; molybdenum was absent. Treatment with chelating agents showed that both non-haem iron and copper were necessary for enzymic activity. The molecule contained five thiol groups, and thiol-binding reagents inhibited the enzyme. Catalase or peroxidase enhanced enzymic activity fivefold; it is postulated that catalase (or other peroxidase) plays a part in the hydroxylation reaction independent of the protection by catalase of enzyme and cofactor from inactivation by a hydroperoxide.


The isolation of cholest-5-ene-3beta,26-diol from human brain. Cholest-5-ene-3beta,26-diol, isolated from human brain, was further characterized by oxidation to 3-oxocholest-4-en-26-ol and to 3-oxocholest-4-en-26-oic acid. Identification was achieved by comparison (by t.l.c., g.l.c. and g.l.c.-mass spectrometry) with corresponding reference compounds derived from kryptogenin.


The isolation of messenger RNA from mammalian cells.


The joint National Cancer Institute of Canada-American Cancer Society study of a test for carcinoembryonic antigen (CEA).


The isolation of trypsin and elastase from moose pancreas (Alces alces) by affinity chromatography on lima-bean protease inhibitor-sepharose resin.


The kinetics of recovery in irradiated colonic mucosa of the mouse.


The lack of effect of methylene blue on struvite crystal formation.


The kinetics of pancreatic amylase secretion and its relationship to volume flow and electrical conductance in the anaesthetized cat. 1. Enzyme secretion in response to short duration vagal stimulation or to rapid I.V. injections of cholecystokinin-pancreozymin (CCK-PZ) or gastrin or to intra-arterial injections of acetylcholine is a function of the volume of juice secreted and not primarily a function of time.2. The output of amylase in response to each stimulus occurred in a constant volume of approximately 15 drops (0.5 ml.) regardless of the rate of background secretin stimulated flow of water and electrolyte.3. It is argued that because amylase secretion occurs in this constant volume, it is due to the rapid secretion of enzyme into the duct system from the acini, and subsequently the secretin stimulated secretion of water and bicarbonate washes the enzyme from the duct system.4. When enzyme secretion is stimulated an increase in the electrical conductance (measured at 1.592 kHz) occurs across the tail of the pancreas. This increased conductance has two components. An early peak associated with the extrusion of enzyme from the acinar cell and a later peak which is probably due to vasodilatation.5. Atropine was without effect on both enzyme secretion and the conductance record when the stimulant was CCK-PZ. Atropine blocked enzyme secretion and both peaks of the conductance record in response to stimulation by acetylcholine. Atropine blocked enzyme secretion and abolished the early phase of the conductance record, on vagal stimulation. It was without effect on the later peak which probably indicates an atropine resistant vasodilation of the pancreatic vessels.6. When the vagus is stimulated on a background of submaximal electrolyte secretion caused by the intravenous infusion of secretin, the volume rate of secretion and the rate of amylase secretion follow a similar time course. The maximal volume response occurred between 7 Hz and 15 Hz and the maximal amylase output per impulse was at 5 Hz.


The lack of congruence between self-concept and public image.


The lack of effects of pretreatment with phenobarbital and chlorpromazine on the acute toxicity of benzene in rats.


The larva of Echinobothrium reesae Ramadevi, 1969 (Cestoda: Diphyllidea) from the body cavity of a pasiphaeid crustacean Leptochela aculeocaudata Paulson, 1875.


The legal control of the use of immobilization drugs in the Republic of South Africa.


The lethal effects of delta9-tetrahydrocannabinol in mice enhanced by pretreatment with SKF 525-A or chloramphenicol.


The life history of Sanguinicola idahoensis sp. n. (Trematoda: Sanguinicolidae), a blood parasite of steelhead trout, Salmo gairdneri Richardson.


The leucocyte antigenic system HL-A as a possible genetic marker of schizophrenia.


The localization of 125-iodide and iodinated (125I) albumin in autoradiographic model experiments.


The location of cells of origin of the fibers in the ventral and the lateral funiculus of the cat's lumbo-sacral cord.


The loss of a therapist through suicide.


The lymphocytic cathepsins B-1 and D activities in multiple sclerosis.


The management of health care organizations--medical vs. administrative orientation: the case of Kupat Holim.


The management of injuries to the brachial plexus.


The management of eclampsia and severe preeclampsia with diazepam and dihydralazine.


The manifesting carrier in Duchenne muscular dystrophy.


The margins of safety in nitrous oxide-oxygen analgesia.


The manubriosternal joint--ananatomicoradiological survey.


The mean geometry of the peptide unit from crystal structure data.


The mechanism and management of headache. Discussion.


The mechanism of enzymatic cellulose degradation. Isolation and some properties of a beta-glucosidase from Trichoderma viride.


The mechanism of prumycin action.

The mechanism of prumycin action.


The mechanism of sugar-dependent stabilisation of gelatin gels.


The mechanism of the hypertensive effect of Brazilian scorpion venom (Tityus serrulatus Lutz E Mello).


The menopausal syndrome.

The menopausal syndrome.


The mercury problem--a trigger for environmental pollution control.


The metabolic cost of increased respiratory work.


The metabolism of (1-14C)arachidonic acid in the neutral glycerides and phosphoglycerides of mouse brain.


The metabolism of calcium and phosphorus and the cellular lipoproteins of the Ehrlich's ascites tumor cell.


The metal ion acceleration of the conversion of trypsinogen to trypsin. Lanthanide ions as calcium ion substitutes.


The microflora and concentrations of volatile fatty acids in the rumen of cattle fed on single component rations.


The mechanics of breathing and stabilization of ventilation in patients with unilateral cerebral infarction.


The mode of morphine uptake into brain slices.


The morphogenetic activity of juvenile hormone and analogues in Spodoptera littoralis Boisd (agrotidae-lepidoptera).


The metabolism of diethylpropion in man; influence of changes in drug formulation and urinary pH.


The mycolic acids of Mycobacterium rhodochrous and Nocardia corallina.


The natural history of liquid lye ingestion. Rationale for aggressive surgical approach.


The nature of the isoantigen of rabbit spermatozoa that reacts with the spermagglutinin of normal homologous serum.


The need for this association to look beyond our own self-interests.


The need to coordinate education programs for disturbed children.


The negator pump for I.V. infusion.

The negator pump for I.V. infusion.


The nature of the serum alkaline phosphatases in liver diseases. The two main alkaline phosphatase isoenzymes in serum from patients with extrahepatic biliary obstruction have been purified. Properties of these isoenzymes, such as electrophoretic mobility, separation on gel filtration, ultracentrifugation characteristics, Michaelis constants, and sensitivity to neuraminidase have been studied and compared with the isoenzymes of liver and bile. The results show that there is an abnormal isoenzyme in the serum from these patients and that this isoenzyme is similar but not identical with the main bile isoenzyme. It is suggested that it may be associated with a lipoprotein carrier.


The neurological lesion in the dystrophic mouse.


The neurosurgical training of foreign medical graduates in the United States.


The new health practitioner in primary care.


The new world of mycotoxins--animal and human health.


The night resident schedule at Fremantle.


The nitroblue tetrazolium (NBT) dye test in determining fever source in lymphoma.


The normal neonatal response to pin-prick.


The numerical taxonomy of Nymphaeaceae Bentham et Hooker. II. Estimation of similarity coefficients.


The nucleolus in primary spermatocytes of Drosophila hydei.


The occurrence and significance of fibrin-fibrinogen degradation products (FDP) in acute infections.


The operative management of ankylosis of the jaws.


The origin of hilar and capsular renal lymph.


The organic matrix of gallstones.

The organic matrix of gallstones. Dissolution of gallstones consisting of cholesterol, calcium carbonate, or calcium phosphate in different solvents left an amorphous organic gel-like substance (the matrix). Matrix from cholesterol stones could be colourless but was usually orange, yellow, or brown while that from calcium carbonate and calcium phosphate stones was almost invariably coloured black or dark brown. These pigments were also shown to be organic and amorphous. The amount of matrix present and its structure varied with the texture of the crystalline material. Irrespective of their composition, laminated pieces of material yielded compact laminated matrix of the same shape as the original piece and areas of loose crystalline material gave small pieces of non-cohesive matrix. Only large cholesterol crystals which usually radiate from the stone nucleus had no associated matrix.


The ostomy program of the American Cancer Society.


The oxygen affinity of haemoglobin St. Luke's.


The passing of lay coroners.

The passing of lay coroners.


The pancreatic exocrine secretion in duodenal ulcer patients before and after selective proximal vagotomy of the stomach.


The pathology and bacteriology of pyelonephritis--post-mortem study.


The pattern of bile salt reflux and acid secretion in sliding hiatal hernia.


The performance of female broilers with non-orthotopic, testicular homografts.


The permeability of perineurium to peroxidase after early undernutrition. An ultrastructural study on rat sciatic nerve.


The occurrence of Hippobosca varieagata Mg in Nigeria; a preliminary observation.


The physician-patient in the recovery and intensive care units.


The pituitary gland and implantation in the tammar wallaby, Macropus eugenii.


The polymeric structure of zinc inosine 5'-monophosphate: x-ray evidence for metal bonding to both N(7) and phosphate.


The possible mode of action of prostaglandins. VII. Evidence of an antifertility effect of prostaglandin E1 in rats.


The pontypridd headache survey.

The pontypridd headache survey.


The possible use of 125I-labeled fibrinogen for the detection of mural thrombosis following myocardial infarction.


The possible role of pulmonary lymphocytes in resistance to lung carcinogenesis of C57 black mice.


The postnatal development of intestinal disaccharidases in the calf.


The potential of pyrolysis-gas chromatography for the pattern individualization of macromolecular materials.


The potency and Group I antigen content of six commercially prepared grass pollen extracts.


The preparation and primary structure of S-peptides from different pancreatic ribonucleases.


The prenatal effect of chloramphenicol on the postnatal development of mice.


The preparation and properties of the components of troponin B.


The presence of zinc in carboxypeptidase C and coupling of the enzyme to sepharose and sephadex.


The prevalence of diabetes mellitus: a study of children and their relatives in a northern Swedish county.


The preservation of Cytoecetes phagocytophila in liquid nitrogen.


The prevalence of macroamylasemia. Further study.


The primary structure of giraffe pancreatic ribonuclease.


The primary sequences and neuromuscular effects of three neurotoxic polypeptides from the venom of Dendroaspis viridis.


The primary structure of goat and sheep pancreatic ribonucleases.


The primary structure of histone F3 from shark erythrocytes.


The primary structure of kidney bean leghemoglobin.


The problem of permeability barrier in mitochondrial respiration: dual effect of protamine on succinate (plus rotenone) oxidation.


The problem-oriented medical record. Time-saving aid in patient care.


The problem of catheter encrustation.

The problem of catheter encrustation. Catheter encrustation was studied in a group of long-stay hospital patients using both latex and silicone catheters. Moisture accounted for 80% by weight of the encrusted material with both catheters. Of the dry weight 90% was composed of protein, calcium, phosphorus, magnesium and uric acid. No relationship was found between the amounts of these substances in the urine and in the encrusted material. High levels of calcium, phosphorus and magnesium were found in the encrusted material from patients infected with Proteus organisms. No direct relationship was found between the duration of catheter drainage and the degree of encrustation, and there was a variation in patient susceptibility to encrustation irrespective of the catheter material. There was significantly less encrustation associated with silicone catheters.


The problem-oriented medical synopsis.

The problem-oriented medical synopsis.


The process of interpersonal adaptation between mothers and their cerebral palsied children.


The profession's own.

The profession's own.


The profile of LH and testosterone secretion in the ram.


The prognostic significance of carotid murmurs in peripheral obliterative atherosclerosis.


The prognostic significance of the ballistocardiogram in ischemic heart disease.


The prognostic value of the cutaneous delayed hypersensitivity response to 2-4 dinitrochlorobenzene in gastrointestinal cancers.


The progressive antithrombin activity and its relations to other factors of the coagulation system in newborns.


The psychogenic and endocrine aspects of sexual behavior.


The projection of the vestibular nerve to the cerebral cortex in the cat. 1. The cerebral cortex in the cat has been examined for responses to contra-lateral vestibular nerve shocks and to natural stimuli.2. Stimulation of the nerve produces short latency (3.5 msec) surface positive responses in very restricted areas. Within these areas, unitary discharges occur during the equivalent negative phase below the surface.3. It has not been possible to evoke unitary activity in these areas by natural stimulation during light anaesthesia with pentobarbitone, chloralose or urethane.4. The distribution and properties of the shock evoked responses have been studied with special attention to the problem of stimulus spread. They are shown to be overlapped by somato-sensory and auditory projections, but to be distinguishable from them. Evidence is presented that previously reported longer latency responses were probably due to stimulus spread.5. Reasons are discussed for the extreme sensitivity of the vestibulocortical pathway to anaesthesia.


The purification of the messenger RNA for silk fibroin.


The radical mastoid operation.

The radical mastoid operation.


The rates of synthesis, uptake and disappearance of (14C)-taurine in eight areas of the rat central nervous system.


The redox potential of the system oxygen--superoxide.


The reactivatibility of cholinesterase inhibited by VX and sarin in man.


The regreening of nitrogen-deficient Chlorella fusca. I. The development of photosynthetic activity during the synchronous regreening of nitrogen-deficient Chlorella.


The relation between adjustment and body image at various age levels.


The regulatory role of divalent cations in human granulocyte chemotaxis. Evidence for an association between calcium exchanges and microtubule assembly. Optimal human granulocyte chemotaxis has been shown to require both calcium and magnesium. Exposure of granulocytes to three different chemotactic factors (C5a, kallikrein, and dialyzable transfer factor) yielded a rapid calcium release, depressed calcium uptake, and was associated with a shift of calcium out of the cytoplasm and into a granule fraction. Colchicine, sodium azide, and cytochalasin B, in concentrations that inhibited chemotaxis, also inhibited calcium release while low concentrations of cytochalasin B, which enhanced chemotaxis, also enhanced calcium release. Microtubule assembly was visualized both in cells suspended in C5a without a chemotactic gradient and in cells actively migrating through a Micropore filter. The data suggest microtubule assembly is regulated, at least, in part, by the level of cytoplasmic calcium. It is proposed that asymmetric assembly of microtubules may be instrumental in imparting the net vector of motion during chemotaxis.


The relation between sexual behavior and seminal fructose in intact and castrated rabbits.


The relation of size at birth and preschool clinical severe malnutrition.


The relationship between the effect of lactate infusion on anxiety states, and their amelioration by carbon dioxide inhalation.


The relationship between the formation of urea and argininosuccinate in a patient with argininosuccinic aciduria studied with labelled precursors.


The relationship between the uniqueness of a given name and personality.


The relationship between urinary infection, cystoscopic appearance, and pathology of the bladder in man. Studies of bladder histology were made in patients with recurrent urinary infection or symptoms of cystitis, with a view to establishing its relationship to symptoms, cystoscopic appearance, and bacilluria. Bladder biopsies were taken from the patients and compared with control material obtained at necropsy. Acute inflammatory changes were inconstant and sometimes sparse. Chronic inflammatory changes were often marked, and were ranked by severity into four grades. There was a statistically significant correlation between the more severe grades and the finding of bacilluria, which was not dependent on sex or age. The grades in patients with recurrent non-bacterial dysuria (;urethritis') lay between those of the controls and the infected patients, and were statistically different from both. There was no correlation between these grades and either symptoms or the finding of trigonal hyperaemia during cystoscopy. However, heavy lymphocytic infiltration, and particularly germinal follicle formation, frequently resulted in macroscopic tubercle-like nodules which were visible on cystoscopy. Such germinal follicles may contribute to local antibacterial defences by their production of immunoglobulins, and may explain the high antibacterial antibody titres sometimes found in the sera of subjects with infection confined to the lower urinary tract.


The relationship between weather and incidence of parturient paresis and mastitis in dairy cows.


The relationship of anemia and thrombocytosis.


The relationship of physicians' medical recording performance to their medical care performance.


The relationship of rate and phrasing to esophageal speech proficiency.


The relationship of study skills to achievement in the first two years of medical school.


The relationship of root-cap slimes to pectins. 1. The patterns of incorporation of radioactivity from d-[U-(14)C]glucose into the pectic components of sections of sycamore roots changed so that sections nearer the tip incorporated relatively more label into arabinose and galactose compared with uronic acid. 2. Radioactive maize root-cap slime was prepared and found to contain three water-soluble component polymers which were electrophoretically (i) neutral, (ii) weakly acidic and (iii) strongly acidic at pH6.5. The neutral component was a glucan. The other components, which could be degraded by trans-elimination, consisted of an acidic backbone chain composed of galacturonic acid and glucose, attached to which were different proportions of neutral sugars. Arabinose, galactose and fucose, the main neutral sugars of the weakly and strongly acidic materials, were absent from the neutral fraction. 3. Fucose was a major sugar in maize-root slime and in a slime of similar composition synthesized by a maize callus of shoot origin. Only trace amounts were found in sycamore, pea and wheat root tips, and in pectin prepared from maize roots and coleoptiles. A high proportion of fucose is therefore a chemical characteristic of maize slime, and slime synthesis indicated a state of differentiation of the tissue. 4. The similarity between the slime and pectin is discussed; slime is a form of pectin modified in such a way as to provide a hydrated protective coating around the root tip.


The relationship of subtle neurologic impairments to disturbances of thinking.


The relative effect of hypoxia and gravity on pulmonary blood flow.


The relationships between arterial oxygen flow rate, oxygen binding by hemoglobin, and oxygen utilization after myocardial infarction. The interrelationships of arterial oxygen flow rate index, oxygen binding by hemoglobin, and oxygen consumption have been examined in patients with acute myocardial infarction. Proportional extraction of oxygen increased in close association with decreasing oxygen flow rate, and hence, whole body oxygen consumption was constant over nearly a three-fold variation in arterial oxygen flow rate. A reduction in hemoglobin-oxygen affinity at in vivo conditions of pH. Pco(2) and temperature also occurred in proportion to the reduction in arterial oxygen flow rate. Therefore, the increased proportional removal of oxygen from arterial blood at low oxygen flow rates, required to maintain oxygen consumption, may have been facilitated by the reduced affinity of hemoglobin for oxygen at in vivo conditions. However, the decrease in affinity did not appear to explain more than 30-40% of the increased extraction. Respiratory alkalosis was a frequent occurrence in these patients and 2,3-diphosphoglycerate was positively associated with blood pH as well as with the time-averaged proportion of deoxyhemoglobin in arterial and venous blood.Hemoglobin-oxygen affinity measured at standard conditions and the mixed venous oxygen saturation were equally good indicators of reduced arterial oxygen flow rate in patients without shock. However, Svo(2) is more easily measured and is a more useful indicator of reduced oxygen flow rate, since its relationship to oxygen flow appears to be independent of affinity changes and time.


The relative significance of electrical spike potentials and intraluminal pressure waves as quantitative indicators of motility.


The relative value of the standard indications for performing a glucose tolerance test in pregnancy.


The relevance of American Life Satisfaction Indices for research on British subjects before and after retirement.


The release of calcium from heart mitochondria by sodium.


The renal hypertensive suspect with coexistent lesions.


The replication of mouse skin epidermal DNA to which is bound 7,12-dimethylbenz(a)anthracene.


The reproductive efficiency of parents whose children convulse when febrile.


The requirements of written scientific expression.


The response of a mouse sarcoma to single and divided doses of x-rays and fast neutrons. The response of an experimental sarcoma to single doses and two fractions of x-rays and fast neutrons has been investigated to test the hypothesis that slowly shrinking sarcomata will reoxygenate poorly and therefore will benefit more from fractionated neutron treatment than from fractionated x-ray treatment, in contrast with rapidly shrinking carcinomata. Neutrons were approximately three times more effective than x-rays, both for single doses and for two fractions given in 48 hours, when regrowth was used as a measure of response. This observation is closely similar to results previously obtained on a rat fibrosarcoma and contrasts with previous results from a mouse mammary carcinoma, and is in agreement with the hypothesis.


The retention of screw posts in root canals.


The retinal pigment epithelium. Chemical composition and structure.


The role of enterostomal therapists and stoma rehabilitation clinics: a second look.


The response of laryngeal afferent fibres to mechanical and chemical stimuli. 1. We have recorded afferent activity from ;single fibres' dissected from the superior laryngeal nerve of anaesthetized cats.2. Units which responded to gentle mechanical stimulation of the larynx epithelium were chosen for study.3. Receptors with myelinated fibres were grouped according to their spontaneous activity. Group 1 fibres had little or no spontaneous activity: group 2 fibres had constant and continuous spontaneous activity.4. Group 1 fibres had a wide range of adaptation rates. Their conduction velocities lay between 3.0 and 30 m/sec. The receptors were generally stimulated by ammonia and distilled water and often by CS riot control agent, 5 and 10% CO(2), 200 ppm SO(2), and cigarette smoke. Histamine, phenyl diguanide, graphite dust, 100 ppm SO(2) and saline drops did not generally excite the fibres.5. Group 2 fibres were slowly adapting. Their conduction velocities ranged between 8.0 and 26.5 m/sec. Ammonia usually, and distilled water sometimes, excited these fibres while 5 and 10% CO(2) mixtures inhibited them. A minority of group 2 fibres were pH sensitive, inhibited by acids and stimulated by alkaline buffers. Cigarette smoke had complex actions, either excitation, inhibition or, at different times, both. Histamine, P.d.g., CS, SO(2), saline drops and dust had no action on these fibres.6. Recordings were made from one unmyelinated fibre (conduction velocity 1.9 m/sec) which responded to stroking of the epithelium with a thread and to histamine, P.d.g. and ammonia vapour applied to the epithelium.7. We consider the site, method of excitation and reflex actions of the different receptors described.


The role of membrane-bound magnesium in the permeability of ghosts to K+.


The role of essential histidines in the mechanism of catalysis of the flavoenzyme, beta-cyclopiazonate oxidocyclase.


The role of plastoquinone in the in vivo photosynthetic cyclic electron transport pathway in algae.


The role of the central nervous system in shock: the centroneurogenic etiology of the respiratory distress syndrome.


The role of the clinical chemistry service.


The role of the dialysis technician in the delivery of hemodialytic therapy.


The role of the hydroxyl ion during vasodilation of arteries caused by DC negative electrical current.


The role of the spleen in active and adoptive immunization.


The role of the intrarenal sympathetic innervation in the development of renal hypertension.


The role of the sulphydryl groups of spleen deoxycytidylate aminohydrolase.


The rudimentary appendix of the cat (Felis domesticus).


The saccharine disease.

The saccharine disease.


The salivary chromosomes of Anopheles barbirostris var. ahomi.


The salivary gland chromosomes of Anopheles tessellatus.


The samaritan movement in Great Britain.


The scope of radioimmunoassay.

The scope of radioimmunoassay.


The search for early indicators of social service need among elderly hospital patients.


The selective blockade by diaminobutyric acid of neuronal uptake of (3H)GABA in rat brain in vivo.


The role of xanthine oxidase in hyperuricemic states.


The second heart sound in left anterior hemiblock.


The self-association of chymotrypsinogen A.


The separation and identification of alpha- and beta-globin messenger ribonucleic acids.


The separation and identification of microquantities of Rauwolfia alkaloids.


The sequence of residues 1-26 of human serum transferrin.


The significance of a fast exchanging superficial calcium fraction for the regulation of contractile force in heart muscle.


The signing of laboratory reports.

The signing of laboratory reports.


The significance of bile acids and aldosterone for the electrical hyperpolarization of human rectum in obese patients treated with intestinal bypass operation.


The single-passage extraction of 18F in rabbit bone.


The site of the respiratory stimulant action of imidazole in cats.


The staphylococcal PEP dependent phosphotransferase system: demonstration of a phosphorylated intermediate of the enzyme I component.


The stereoselective inhibition of lipolysis by nonphenolic phenethylamines.


The stoichiometry and dynamics of lecithin-cholesterol clusters in bilayer membranes.


The structure of methyl alpha-D-galacturonic acid methyl ester.


The study of some correlations between the blood-group OAB and the pathology of the thyroid gland.


The subclavian steal syndrome--a report of 14 cases.


The subgenus Persicargas (Ixodoidea: Argasidae: Argas). 19. Preliminary studies on diapause in A. (P.) arboreus Kaiser, Hoogstraal & Kohls.


The subsynaptosomal localization of histamine, histidine decarboxylase and histamine methyltransferase in rat hypothalamus.


The suitability of an intestinal flora with colonization resistance factor for SPF mice, rats and gerbils.


The steel whisker tube in chronic secretory otitis media.


The surgical anatomy of the porta hepatis.


The surgical approach to morbid obesity.


The susceptibility of the mouse immunoglobulin subclasses to suppression by high doses of antigen.


The symptoms of neuro-fibroma of the 8th nerve.


The synthesis and assembly of immunoglobulins by malignant human plasmacytes. 3. Heterogeneity in IgA polymer assembly.


The synthesis of globin peptide chains in sickle-cell disease.


The synthesis of methyl 2-acetamido-3,6-anhydro-2-deoxy-alpha-D-glucopyranoside and derivatives.


The synthesis of oligopeptidyl-tRNA.

The synthesis of oligopeptidyl-tRNA.


The taxonomic status of Hirstionyssus butantanensis (Fonseca, 1932) (Acari: Mesostigmata).


The teaching and use of the problem-oriented medical record in medical schools.


The teaching of medical staff in a mission hospital.


The technique and complications of upper tibial osteotomy. A review of 226 operations.


The temperature dependence of chlorophyll fluorescence yield in photosystem 2.


The temperature-dependence of fluorescence as an aid to the identification of oxybarbiturates.


The termination of the common bile duct.


The test of inhibition of lymphocyte migration in an electric field.


The thermal induced helix--beta transition of poly(N epsilon-methyl-L-lysine) and poly(N delta-ethyl-L-ornithine) in aqueous solution.


The three-tier approach to mutagenicity screening and the concept of radiation-equivalent dose.


The timing of juvenile hormone release for ovarian maturation in Manduca sexta.


The toxic effect of human serum on animal and plant cell growth. A comparative study of the effect of human serum in vitro on Ehrlich ascites tumour cell growth and plant root growth (Triticum sativum lam.).


The toxic effects of human serum on ehrlich ascites tumour cells in in vitro culture.


The trace detection of some non-volatile nitrosamines by combined gas chromatography and mass spectrometry.


The trace metal detection technique (TMDT): a report outlining a procedure for photographing results in color, and some factors influencing the results in controlled laboratory tests.


The training of the district physician for developing countries.


The transcapillary escape rate of T-1824 in newborn infants of diabetic mothers and newborn infants with respiratory distress or birth asphyxia.


The treatment of allergic emergencies.

The treatment of allergic emergencies.


The transamination of glutamate and aspartate during absorption in vitro by small intestine of chicken, guinea-pig and rat. 1. Procedures are described for direct measurement of the extent and rate of transamination of glutamate and aspartate over periods of up to 90 min, during absorption in vitro by the small intestine of chicken, guinea-pig, and rat.2. During absorption of dicarboxylic amino acids by rat small intestinal segments circulated through the lumen in vitro, alanine contributed up to 85% of the amino acids appearing in the fluid secreted at the serosal surface. In guinea-pig and chicken intestine, the proportion of alanine in the secreted amino acids did not exceed 60%.3. For the different species studied, a relationship was found between the extent to which the dicarboxylic amino acids were transaminated to alanine and the total amount of GPT found in other studies to be present in the intestinal mucosa. In both rat and guinea-pig small intestine, the proportion of alanine in the total amino acids appearing at the serosal surface was similar in the jejunum and ileum. The rate of appearance of alanine in serosal fluid was greater in the ileum than in the jejunum of the rat.4. Reasons are given for supposing that for all the species studied there is a limit to the capacity of the small intestinal mucosa to subject free dicarboxylic amino acids to transamination. It is concluded, however, that it is unlikely that this capacity will be exceeded under in vivo conditions.


The treatment of idiopathic hyperhidrosis by glycopyrronium bromide and tap water iontophoresis.


The treatment of locally advanced cancer of the head and neck with intra-arterial cytotoxics, cobalt, and hyperbaric oxygen therapy.


The trypsin-catalyzed hydrolysis of N alpha-benzyloxycarbonyl-L-lysine p-nitrophenyl ester in dimethylsulfoxide at sub-zero temperatures.


The treatment of parkinsonism with levodopa.


The ultrasonic detection of incompetent perforating veins.


The ultrastructure of the lymphoid follicles of the chick bursa of Fabricius.


The treatment of epistaxis with the nasostat.


The ultrastructure of the carotid body in chronically hypoxic rabbits. 1. The ultrastructure of the carotid body in the rabbit has been examined by electron microscopy.2. A comparison was made between the ultrastructure of the carotid bodies in sea level rabbits, in rabbits which had been exposed to hypoxia equivalent to an altitude of 6000 m for 7 days and in rabbits which always had lived at an altitude of 4000-4300 m.3. We could not detect any difference in the ultrastructure between the two groups of hypoxic rabbits.4. When the hypoxic rabbits were compared with sea level rabbits there was a marked increase in the number of dense cored vesicles and mitochondria in the type I cells in the hypoxic rabbits. The Golgi region also appeared to be enlarged in the type I cells in the hypoxic rabbits.5. The finding suggests that in the rabbit the production of amines, probably dopamine, within the type I cells is increased during prolonged hypoxia which might explain the lowered ventilatory response to hypoxia observed in human high altitude residents.6. If the carotid bodies are organs of internal secretion the finding is compatible with an increased production of a hormone produced within the type I cells.


The ultrastructure of the small intestinal mucosa in the developing human fetus.


The ultrastructure of the parotid gland on some East African wild ungulates.


The uptake of norepinephrine by rat uterine subepithelial cells under normal and experimental conditions. On specified days of the estrus cycle, pregnancy, pseudopregnancy, or following administration of estradiol-17 beta, progesterone, or both, nulliparous, ovariectomized rats were assigned to 1 of 3 treatment groups.  Group 1 received nialamide and norepinephrine 5 hours and 15 minutes, respectively, before killing.  Group 2 received nialamide alone 5 hours before killing.  Group 3 received L-dihydroxyphenylalanine 2 hours before killing.  Pregnant, pseudopregnant, and progesterone-treated rats from Group 1 showed a greenish-yellow fluorescence in uterine subepithelial cells.  Groups 2 and 3 did not show this fluorescence.  It was suggested that this fluorescence was due to the extraneuronal uptake of norepinephrine, and that progesterone is necessary for the uptake of norepinephrine by subepithelial cells since no florescence was observed in the rat estrus  cycle but ovariectomized rats treated with progesterone showed florescence.


The uptake of triated thymidine by human fetal epidermis.


The uptake of tocopherols by the developing rat fetus.


The use of chemical spot tests kits for the presumptive identification of narcotics and drugs of abuse.


The uptake of GABA into rat spinal roots.


The use of feedback in the reduction of foot dragging in a cerebral palsied client.


The use of genetic relationships among cattle breeds in the formulation of rational breeding policies: an example with South Devon (South Africa) and Gelbvieh (Germany).


The use of kitasamycin in a general practice situation.


The use of modified cellulose papers in routine toxicological analysis. 3. Xanthine CNS stimulants and antipyretics.


The use of modified cellulose papers in routine toxicological analysis. 4. Alkaloids.


The use of photopic saturation in determining the fundamental spectral sensitivity curves.


The use of non-loaded, conscious dogs for the assessment of diuretic activity.


The use of radiolabelled T1 ribonuclease to monitor the efficiency of Edman degradations. A simple radiolabel tracer method is presented for monitoring the efficiency of the first ten cycles of an Edman degradation. This method consists of adding a very small amount of radiolabelled S-carboxymethylated T(1) ribonuclease to the protein to be sequenced, and counting the radioactivity of a small sample from each of the degradative cycles.


The use of the T4 DNA polymerase in identification of 3' terminal nucleotide sequences of duplex DNA.


The value of ultrasonic scanning in the diagnosis of intra-abdominal abscesses and hematomas.


The value of creatine phosphokinase (CPK) in determining intraoperative myocardial ischemia.


The victims of mentally disordered female offenders.


The vital importance to South Africa of food production by the White agricultural sector.


The way I see it: In 107 years the CMA has earned position as the representative of all Canada's physicians.


The worried-well revisited.

The worried-well revisited.


The use of epidemiology in animal disease.


The ANA: can a professional association be a trade union, too?


The Baker Act can work.

The Baker Act can work.


The Dean's letter--1974. KUMC-Wichita State University Branch.


The Dodd-Cockett operation. An analysis of the long-term prognosis.


The Eaton-Lambert syndrome in ocular myasthenia gravis.


The DNA polymerases of KB cells.

The DNA polymerases of KB cells.


The Government's view of where we stand in drug law enforcement.


The Gulf Coast tick: evidence of a pheromone produced by males.


The Jewish Hospital of St. Louis. Therapeutic grand rounds number 7. An approach to disorders of uric acid metabolism.


The Limulus test and gram-negative bacillary sepsis.


The MASA syndrome: a new heritable mental retardation syndrome.


The New York Medical College Summer Program: remedial education for medical school admission.


The NBT test in bacterial and non-bacterial pharyngitis.


The Pestalozzi Children's Village in Trogen, Switerland.


The Syrijet anesthetic gun for paracervical and uterosacral block.


The X prime descent in jugular contour nomenclature and recognition.


The XYY syndrome: reality or myth?

The XYY syndrome: reality or myth?


The 1973 in-training examination in obstetrics and gynecology.


Thecamoeba hoffmani sp. n. (Amoebida: Thecamoebidae) from gills of fingerling salmonid fish.


Theoretical analysis of conformations of Ac-Gly-L-Ala-Gly-NHMe with intramolecular hydrogen bonds.


Theoretical calculations on an acetic acid, 5-methylimidazole, methanol hydrogen bond network: a model charge relay system.


Theoretical prediction of highway noise fluctuations.


Therapeutic endoscopy: removal of an unusual foreign object from the stomach.


Therapist attitudes and premature termination in family and individual therapy.


Thermal tolerance of the mongoose, Herpestes auropunctatus.


Thermal titration: application of calorimetry to the study of plasma coagulation.


Thermodynamics of biological processes.

Thermodynamics of biological processes.


Thermoregulatory responses in normal and cold acclimated rabbits.


Thiamine deficiency encephalopathy in the developing rat.


Thin-layer chromatographic determination of simple phenols in microbial extracts.


Thin-layer chromatographic separation of the Z and E rotational isomers of alpha-N-nitroso-N-alkylamino acids.


Thin-layer chromatography of amino acids in blood.


Thin-layer chromatography in the detection of poisoning by pesticides.


Thin-layer chromatography of arginine, lysine and ornithine decarboxylase activity among Pseudomonas spp. and Enterobacteriaceae.


Thin-layer chromatography of darvon compound-65.


Thought disorder in schizophrenia, length of hospitalization, and clinical status ratings: validity for the Feldman-Drasgow visual-verbal test.


Three abundance classes in HeLa cell messenger RNA.


Three medical students confront death on a pediatric ward. A case report.


Three-dimensional structure of hemoglobin from the polychaete annelid, Glycera dibranchiata, at 2.5 A resolution.


Three-dimensional visualization of the intact thorax and contents: a technique for cross-sectional reconstruction from multiplanar x-ray views.


Thrombolysis with streptokinase in rabbits. Dose response, fibrin-clot specificity and laboratory evaluation of fibrinolytic effect.


Thrombophlebitis-induced median neuropathy.


Thubunaea cnemidophorus in Nevada rattlesnakes.


Thrombus formation in the arterial and venous circulation in thrombocytopenic dogs.


Thymic teratoma. Spontaneous rupture into pleural space.


Thymomas: clinicopathologic features, therapy, and prognosis.


Thyroid function assay using the effective thyroxine ratio (ETR) in infancy.


Thyroid storm.

Thyroid storm.


Thyroid function in patients treated with radioactive iodine for thyrotoxicosis. A series of 105 patients treated at least two years earlier with radioactive iodine for thyrotoxicosis have been surveyed. Eighty-five patients (81%) were euthyroid clinically and on the basis of routine thyroid function tests. Of the euthyroid patients 46 (54%) had normal thyroid-stimulating hormone (TSH) levels and 39 (46%) had raised TSH levels. There was no difference in serum triiodothyronine levels between these two groups but the serum protein bound iodine and serum thyroxine, though still well within the normal range, were significantly lower in the group with raised TSH levels. The serum cholesterol was also significantly higher in this latter group.Most of the euthyroid patients were seen again a year later. None had become hypothyroid and neither those with normal nor those with raised TSH levels showed any evidence of a decline in the level of serum thyroxine.It is concluded that raised serum TSH levels in patients treated with iodine-131 are not necessarily indicative of hypothyroidism. There is no indication that patients who have this abnormality become overtly hypothyroid over a 12-month follow up.


Thyrotoxicosis and periodic paralysis: improvement with beta blockade.


Thumb and finger sucking: analysis of contributory factors in 1258 children.


Tickle responses in eczema patients and normal controls.


Time interval between e.c.g. R wave and peak flow velocity in leg arteries of normal humans.


Thyroxine and brain catecholamines: increased transmitter synthesis and increased receptor sensitivity.


Tissue localization of 7- and 8-hydroxychlorpromazines.


Time resolved fluorescence of flavin adenine dinucleotide.


Titrations of barbiturates and sulfa drugs in 3-methyl-2-oxazolidone.


Tobacco mosaic virus reconstitution in the presence of 8 S TMV-protein component.


Tobacco smoking and sex ratios in the United States. Results of an investigation into the effect of smoking on U.S. age-specific sex ratios indicate that the contribution of smoking to imablances in these ratios in substantial.  1st, the mathematics of the stationary population model is used to analyze the overall trend in age-specific stationary population sex ratios for 1910 and 1962, without reference to smoking.  As age-specific and sex-specific mortality rates at the younger ages declined to nearly zero during this period, most male-female differences between those rates also declined.  As a result, sex ratios at the younger ages decreased more slowly with age in 1962 than in 1910.  Average U.S. annual cigarette consumption per person for ages 15 and over increased from 49 in 1910 to 3958 in 1962.  Splitting overall age-specific and sex-specific mortality rates into smoking and nonsmoking components, the analysis is extended to examine the effects of smoking, utilizing age-specific mortality rates derived by linearly interpolating and extrapolating American Cancer Society mortality data.  Percent reductions in age-specific sex ratios due to smoking probably represent fairly accurately the true values in the U.S. population in 1962.  Reductions in sex ratios at each age from what they would have been if the total population had been nonsmoking varies from 0% at age 35 to 20% at age 85.  It is apparent that smoking has a cumulative effect on the sex ratio with increased age.


Tobramycin ototoxicity.

Tobramycin ototoxicity.


Tolazamide hepatotoxicity. A case report.


Topographic atlas of catecholamine and acetylcholinesterase-containing neurons in the rat brain. I. Forebrain (telencephalon, diencephalon).


Total anuria as a manifestation of spontaneous rupture of an apparently normal kidney: report of a case.


Topographic atlas of catecholamine and acetylcholinesterase-containing neurons in the rat brain. II. Hindbrain (mesencephalon, rhombencephalon).


Total plasma bile acid concentration in chronic hepatitis and cirrhosis; fasting values and effect of intraduodenal bile salt administration.


Total synthesis of steroids. V. Synthesis of rac-3-methoxy-14alpha-hydroxy-8alpha-estra-1,3,5(10)-triene-11,17-dione and its derivatives.


Towards three-dimensional "electron microscopy" at atomic resolution.


Toxic effect of patent blue violet on rat lymph node lymphocytes.


Toxicity of methylmercury in neonatal cats.


Toxicity of protein hydrolysate solutions: correlation of glutamate dose and neuronal necrosis to plasma amino acid levels in young mice.


Toxicologic studies on the avicide 3-chloro-p-toluidine.


Trace elements in precipitation and cloud water in the area of Heidelberg, measured by instrumental neutron activation analysis.


Toxicologic, reproductive and teratologic studies of colestipol hydrochloride, a new bile acid sequestrant.


Total rectal prolapse and total genital prolapse: A series of 17 cases.


Tracheostomy tube: ideal versus real.

Tracheostomy tube: ideal versus real.


Tracheobronchomegaly: the Mounier-Kuhn syndrome.


Training of pathologists by a system of modules. The training requirements of the individual pathology subjects within laboratory medicine are changing rapidly and there is a trend to earlier specialization. A new training scheme based on a system of 10 modules, each of six months' duration, is suggested. Six of the modules comprise obligatory specialist training while the remaining four provide an element of choice both in subject matter and timing. This allows the advantages of multidisciplinary training to be retained, despite earlier specialization, since the subjects studied need not necessarily be restricted to the traditional pathology disciplines. The system allows 20% of training time to be devoted to full-time research and has been designed to be attractive to trainees in general medicine. Modular training provides an inherently flexible system which can readily be adapted to future developments in pathology and medicine.


Transient global amnesia.

Transient global amnesia.


Transformations of steroids by cell-free preparations of Penicillium lilacinum NRRL 895. IV. Enzyme catalyzed acyl transfer.


Transient state isoelectric focusing: theory.


Transitory cortical blindness following head injury.


Transient state isoelectric focusing: effects of zone load and carrier ampholyte concentration on the kinetics of defocusing and refocusing in sucrose density gradients.


Transperitoneal approach to renal pedicle.


Transphoresis and isotachophoresis--automatable fast analysis of electrolytes, proteins, and cells, with suppression of gravitational effects.


Tracheostome maintenance by obturator for prolonged or future need.


Transport of D-glucose by brush border membranes isolated from the renal cortex.


Transport phenomena in ion exchange membranes. Membrane potentials and solvent transference.


Transport, capacitation and fertilizing ability of epididymal spermatozoa.


Transportation of the great vessels. Report of a case.


Transthoracic fundoplication for short esophagus in children.


Traumatic avulsion of the renal pelvis: repair with capsular flap.


Treasury dogs in action.

Treasury dogs in action.


Treatment of a situational phobia--a case for running.


Treatment of itching ears with fluocinolone acetonide.


Treatment of diabetic coma with continuous low-dose infusion of insulin. Thirty-eight patients in diabetic coma from four different centres were treated with a continuous low-dose intravenous infusion of insulin at an average dose of 7.2 IU/hr. All patients recovered rapidly except for one profoundly shocked patient who died. The mean fall in plasma glucose was 58% four hours after the start of insulin. Blood ketone bodies and plasma free fatty acids showed a similar response. There was no significant difference in plasma glucose response according to severity of acidosis or previous treatment with insulin. Hypokalaemia was uncommon. In the treatment of diabetic coma this technique has proved simple, safe, and effective.


Trends in development of abilities related to somatic growth.


Treatment of refractory heart failure with infusion of nitroprusside.


Treatment of severe diabetes mellitus by insulin infusion. A new and simple form of insulin therapy for diabetic hyperglycaemia and ketoacidosis has been developed using a continuous intravenous infusion of insulin at a rate of 2.4 U/hr to maintain serum insulin concentration at physiological levels. This rate raises the mean serum insulin to 83 muU/ml and has a therapeutic effect which is not augmented by higher infusion rates. The response to such low doses of insulin indicates a need for a reappraisal of currently held theories about insulin resistance in diabetic ketoacidosis. In 11 diabetic patients with a mean plasma glucose of 514 mg/100 ml this therapy produced continuous falls in plasma glucose at a mean rate of 75 mg/100 ml/hr, and 10 out of 11 patients recovered within eight hours. This form of therapy is simple to institute, not complicated by hypoglycaemia, and avoids the confusion and empiricism of previously described forms of therapy.


Triamiphos: long-term toxicity and three-generation reproduction studies in rats.


Trichlorphon as a safe insecticide for use on birds of prey.


Tricuspid annuloplasty. Five and one-half years' experience with 78 patients.


Trichophytin extraction: biological comparison of trichophytin extracted from Trichophyton mentagrophytes grown in a complex medium and a defined medium. The extraction of antigens (trichophytin) from Trichophyton mentagrophytes var. asteroides grown in both a complex medium and a defined medium proved to be reproducible and feasible. These extracts were first evaluated by skin testing in both infected and noninfected guinea pigs. Further evaluation and standardization was accomplished in selected humans by comparing these antigens to a trichophytin known to elicit allergic reactions to the dermatophytes. The trichophytins produced by this extraction procedure gave no false positive (or negative) skin test reactions. These antigens did, however, reliably elicit allergic sensitivity of both the immediate and delayed type. The potency of both complex and defined media antigen was shown to be equal to that of the standard trichophytin.


Traumatic tympanic perforation.

Traumatic tympanic perforation.


Triplet states and cis-trans photoisomerization processes in the Schiff bases of retinal isomers.


Trisomy for the distal segment of chromosome 13: a new syndrome.


Trisomy for the proximal segment of the long arm of chromosome 13: a new entity?


Trisomy for the short arms of chromosome 9 in two generations, with balanced translocations t(15pplus;9qminus) in three generations.


Tritiated digoxin. XX. Tissue distribution in experimental myocardial infarction.


Tritiated glycerol triether as an oil phase marker in man. 3H-labeled glycerol triether has been suggested as a marker of the oil phase during digestion and absorption of a lipid test meal. This study examines the behavior of this isotope in the human alimentary tract. The results suggest that it is completely recovered from the gastrointestinal tract, and thus it remains solely with the oil phase of emulsions in vivo and with the oil phase of intestinal aspirates. (3)H-labeled glycerol triether may thus be an appropriate marker of the oil phase for use in human studies of lipid absorption.


Tuberculoid granulomata in regional lymph nodes of malignant cutaneous melanoma.


Tuberculosis in rural Haiti.

Tuberculosis in rural Haiti.


Tuberculosis in uremic pericarditis.

Tuberculosis in uremic pericarditis.


Tuberculosis of the nose and paranasal sinuses.


Tuberous sclerosis with fusiform aneurysms of both internal carotid arteries manifested by unilateral visual loss and papilledema.


Tumor implants in the mediastinum of mice.


Tumorophilic Gallium-67 scanning: a retrospective study.


Turnover times in psoriasis.

Turnover times in psoriasis.


Tropical medicine in Canada--problems and prospects.


Turnover numbers for ionophore-catalyzed cation transport across the mitochondrial membrane.


Two active structures for hemicholinium-like action.


Twitch potentiation by potassium contractures in single muscle fibres of the frog. 1. The modifications of isometric twitches after K contractures have been studied in single muscle fibres from frog muscles.2. The twitch was greatly enhanced and somewhat prolonged after a conditioning K contracture. This potentiating effect was more evident in fibres having low values of the ratio control twitch tension/tetanus tension (P/P(0)).3. In most of the fibres, the time course of the decay of the potentiation phenomenon could be represented by the sum of three negative exponentials with average half-times of 9.1, 40 and 485 sec.4. Between 3 and 10 min after the onset of the twitch potentiation the resting potential and action potential were unchanged.5. Mn blocked the K contractures and prevented the onset of the twitch potentiation.6. 40-140 sec after inducing a K contracture with 30 or 40 mM-K, a second exposure to the same [K] evoked a tension equivalent only to 57% of the first one. This partial refractoriness of the fibres is not seen when both contractures were elicited with 190 mM-K, and contrasts with the full recovery and potentiation of the twitch after a K contracture.


Two cases of "recovery" in Kanner syndrome.


Two entities in angiolipoma. A study of 459 cases of lipoma with review of literature on infiltrating angiolipoma.


Two types of autosomal recessive pseudoxanthoma elasticum.


Two-dimensional polyacrylamide gel electrophoresis of eukaryotic ribosomal proteins.


Two-tracer method for rapid determination of residual volume.


Two-phase partition studies of alkali cation complexation by ionophores.


Two-way avoidance learning in pigeons after olfactory nerve section.


Two-Angstrom crystal structure of oxidized Chromatium high potential iron protein.


Types of synapses in the claustrum of the cat. Basing on structure of synaptic vesicles, symmetry of presynaptic and postsynaptic densities, and size of synaptic boutons, various types of synapses were found in the claustrum. Most of the synapses connect axon terminals with dendritic spines or small dendrities. They are usually asymmetrical with evident postsynaptic thickening. To this type, synapses between corticofugal axons, and claustral cells belong. Synapses between the axon terminals and larger dendrites or cell pericarion are much less frequent, 1-10 synaptic boutons adhering to pericarion were found on a single section of the claustral cell. Axoaxonic and crest-synapses also were found.


Tyrosine and phenylalanine concentrations in haemolymph and tissues of the American cockroach, Periplaneta americana, during metamorphosis.


TB or not TB: the Mantoux test reviewed.


TEAM vs. DAU: a study of clinical productivity.


TLC separation and identification of diastereomers of D-ergonovine maleate.


U.S. medical school faculty members who earned M.D. degrees in foreign medical schools.


Udder disease and membrane material in milk.


Ultrasonic measurement of sound velocity in the pregnant and the non-pregnant cervix uteri.


Ulcerative colitis, autoimmune epiphenomena, and colonic cancer.


Ultrasound in the diagnosis of hydatidiform mole.


Ultrastructural changes during cardiogenesis in lead poisoning. I. Endocardial cushion tissue.


Ultrastructural changes in human platelets during arachidonic acid-induced aggregation.


Ultrastructural distribution and redistribution of alloantigens and concanavalin A receptors on the surface of mouse lymphocytes.


Ultrastructural features of ectodermal--mesenchymal relationships in the developing limb of Xenopus laevis.


Ultrastructural observations on closure of the soft palate in hamsters.


Ultrastructural studies of acute hypersensitivity pneumonitis in rabbits.


Ultrastructural study of Pierce's disease bacterium in grape xylem tissue. The rod-shaped rickettsia-like bacteria of Pierce's disease measure about 0.25 to 0.50 mum in diameter and 1.0 to 4.0 mum long. The bacteria have a cell wall consisting of a trilaminar outer membrane and two intermediate low-density layers separated by a dense intermediate layer. A trilaminar cytoplasmic membrane is also present, resulting in a total wall complex thickness of 25 to 40 nm. A periodic infolding of the outer membrane and intermediate layers of the wall give the wall surface a ridged apperance. The ridges appear to go around the long axis of the cell, possibly in the form of spirals. Ribosomes and nuclear regions with easily visible deoxyribonucleic acid strands and clumps are distributed throughout the cytoplasm. Binary fission, during which the cell wall and cytoplasmic membrane folded inward to partition the cell, was observed. In the xylem of infected grapes, the bacteria are either distributed evenly throughout the lumen of the xylem vessel or appressed along the inner surface of the vessel walls in an electron-lucent matrix.


Ultrastructural studies of induced morphogenesis by Aspergillus parasiticus.


Ultrastructural studies on two cases of porokeratosis of Mibelli.


Ultrastructure of the arachnoid membrane in man.


Ultrastructure of the developing erythrocytes.


Ultrastructure of the outer cortex and the pia mater in man.


Ultrastructure of Entamoeba moshkovskii with particular regard to the presence of surface active lysosomes.


Ultraviolet-induced reactions of thymine and uracil in the presence of cysteine.


Ultrastructural alterations in the dog brain after profound hypothermia induced by extracorporeal circuit.


Unbalanced globin chain synthesis in reticulocytes of sickle cell trait individuals with low concentrations of hemoglobin S.


Uncertainty of growth of cell populations in cancer.


Understanding persons as persons.

Understanding persons as persons.


United States District Court for the District of Columbia.


Unequivocal assignments of NH proton magnetic resonance bands in oxytocin using 2H- and 15N-substituted molecules.


Unusual fracture and orthopedic problems.


Unusual ultrastructural features in alveolar rhabdomyosarcoma.


Unusual unilateral blunt chest trauma without rib fractures leading to pulmonary laceration requiring pneumonectomy.


Unusual urethral obstruction in a dog.

Unusual urethral obstruction in a dog.


Upper intestinal endoscopy in the RAF: the radiologist's view.


Upper intestinal endoscopy in the RAF: the physician's view.


Upper oesophageal sphincter yield pressure in normal subjects and in patients with gastro-oesophageal reflux.


Upper limit to stapes displacement: implications for hearing loss.


Uptake and metabolism of cholesterol and cholesteryl oleate by Phytophthora cactorum.


Uptake and degradation of a polypeptide antigen by stimulated and unstimulated macrophages from responder and non-responder mice.


Uptake and metabolism of exogenous uridine by superfused rat liver slices.


Unusual connective tissue manifestations of hemochromatosis.


Uptake and metabolism of tritiated oestradiol and oestrone by human endometrial and myometrial tissue in vitro.


Uptake and subcellular cleavage of organomercury compounds by rat liver and kidney.


Uptake and release of ferritin iron. Surface effects and exchange within the crystalline core. The uptake and subsequent release of iron by apoferritin and ferritin was studied by using labelled iron ((59)Fe). The experimental results are consistent with predictions arising from a model system developed in the interpretation of previous experiments. In this model, uptake and release of ferritin iron is controlled by the available surface area of the small crystalline particles of hydrous ferric oxide found within the ferritin molecule. Evidence is also presented for the exchange of Fe(3+) ions among the various cation sites within these crystallites.


Uptake of (6,7-3H)oestradiol-17beta by normal and abnormal human endometrium.


Uptake of acetylcholine and choline into rat brain cortical slices and synaptosomes as related to 32Pi incorporation into their phospholipids.


Uptake of calcium ions by synaptosomes from rat brain.


Urea and creatinine production and excretion in urine during and after prolonged heavy exercise.


Urban health problems in Japan: an epidemiological analysis using tuberculosis as an example.


Ureteral function. I. Simultaneous monitoring of ureteral peristalsis.


Ureteroneocystostomy in children with vesicoureteral reflux. Experience with 150 reimplanted ureters.


Uridine incorporation and pyruvate metabolism in rabbit eggs cultured in vitro at normal and elevated temperatures.


Urinary amino acid patterns in cystinuric families.


Urinary excretion of acetaminophen by the rat.


Urinary ascites secondary to ureteroperitoneal fistula.


Urinary free cortisol excretion during growth and aging: correlation with cortisol production rate and 17-hydroxycorticosteroid excretion.


Urinary metabolites of D,L-1,2-bis(5-(6)-methoxy-2-benzimidazolyl)-1,2-ethanediol in mice.


Urinary tract infections in newborns, infants and children.


Uroradiography. Benign leiomyoma.

Uroradiography. Benign leiomyoma.


Urine and stool collection for metabolic studies in the newborn.


Use of amoxycillin in chest infections in the elderly. A double-blind study.


Use of ion-exchange resins for removing prostaglandins from human urine prior to radioimmunoassay.


Use of the cytograf to determine cytotoxicity in fibroblast cell cultures.


Use of the personal orientation inventory with state hospital alcoholics.


Use of 123I for thyroid uptake measurements and depression of 131-I thyroid uptakes by incomplete dissolution of capsule filler.


Use of the A-B variable in a crisis phone setting.


Using premedical students in a community hospital summer volunteer program.


Uterine contractility patterns of the outer and inner zones of the myometrium.


Utilization and turnover rate of fructose during continuous intravenous infusion in pre-term and term newborns in dependence on age.


Uterine development in prepubertal gilts after single or multiple stimulation by gonadotrophins.


Utilization of choline-o-sulphate as a sulphur source for growth by a Pseudomonas isolate.


Utilization of health services in developing countries--Tunisia.


UNICEF in India.

UNICEF in India.


Vaccination against the nematode Trichostrongylus colubriformis. I. Vaccination of guinea-pigs with worm homogenates and soluble products released during in vitro maintenance.


Vagal control of breathing pattern independent of lung inflation in conscious dogs.


Vaccinia virus cytotoxin(s).

Vaccinia virus cytotoxin(s).


Valence tautomerism of singly protonated 9-aminoacridine and its implications for intercalative interactions with nucleic acids.


Vagotomy and the external function of the pancreas.


Valine-sensitive nonketotic hyperglycinemia. Case report.


Vanadium in the living world.

Vanadium in the living world.


Variability of aflatoxin test results.

Variability of aflatoxin test results.


Variation among physicians in use of laboratory tests: relation to quality of care.


Variation in glomerular sialic acid content in diabetes and as the result of ageing.


Variation in rDNA redundancy level and nucleolar organizer length in normal and variant lines of the Mexican axolotl.