A kinetic study of pig liver pyruvate kinase activated by fructose diphosphate. The paper reports a study of the reaction between phosphoenolpyruvate, ADP and Mg(2+) catalysed by pig liver pyruvate kinase when activated by fructose diphosphate and K(+). The experimental results are consistent with two non-sequential mechanisms in which the substrates and products of the reaction are phosphoenolpyruvate, ADP, Mg(2+), pyruvate and MgATP. Pyruvate release occurs before ADP binding. Two Mg(2+) ions are involved, though the two Mg(2+)-binding sites cannot be occupied simultaneously. An isomerized enzyme complex forms before release of MgATP. Values were determined for the Michaelis constants of the reaction. Apparent MgATP inhibition constants are also given.


A kinetic evaluation of monoamine oxidase activity in rat liver mitochondrial outer membranes. 1. A preparation of mitochondrial outer membranes from rat liver can be shown to contain two kinetically distinct monoamine oxidase activities. These activities are distinguishable by their different sensitivities to the irreversible inhibitor clorgyline, and by the effect of the reversible inhibitors benzyl cyanide and 4-cyanophenol. 2. The substrate specificities of the preparation and the two enzyme species have been elucidated.


A mathematical analysis of the relation between (bacterio) chlorophyll fluorescence yield and the concentration of reaction centre traps in photosynthesis.


A method for the determination of volatile fatty acids in the blood plasma of ruminant animals.


A method of statistical neurodynamics.

A method of statistical neurodynamics.


A method for isolation of abnormal haemoglobins with high oxygen affinity due to a frozen quaternary r-structure: application to Hb Creteil alpha 2 A beta 2 (F5) 89 ASN.


A micro method for the estimation of the individual glycosides in digitalis leaves and pharmaceutical preparations.


A micro pCO2 electrode.

A micro pCO2 electrode.


A microspectrofluorometer with epi-illumination operated under computer control.


A model for cardiogenic shock by coronary artery microembolization on calves.


A model for life changes and illness research. Cross-cultural data from the Norwegian Navy.


A model to describe binding differences between calcium and the lanthanides in biological systems.


A model for phase transitions in lipid bilayers and biological membranes.


A multi-element serum standard for neutron activation analysis.


A modular, community-oriented treatment program.


A multichannel ultrasonic biotelemetry system for monitoring marine animal behavior at sea.


A neonatal intensive care unit: a four-year summary.


A mutant of human red cell pyruvate kinase with high affinity for phosphoenolpyruvate.


A new approach to evaluating-problem-solving in medical students.


A new approach to disturbed children: The Medical College School Program.


A new bronchus clamp.

A new bronchus clamp.


A new concept of plasma calcium homeostasis in the rat.


A new curriculum and assessment scheme for obstetrics and gynaecology.


A new format for stream of life charts.

A new format for stream of life charts.


A new delta chain variant, haemoglobin-A2-Melbourne or alpha2 delta2 43Glu-Lys(CD2).


A new haemoglobin J from Turkey--Hb Ankara (beta10 (A7) Ala-Asp).


A new method for the reductive coupling of carbonyls to olefins. Synthesis of beta-carotene.


A new method to determine sugar-base torsion in purine nucleosides and nucleotides.


A new method to estimate apparent dissociation constants for desensitizing agonists without using antagonists.


A new name proposed for Assamia Dayal et Gupta.


A new neurosurgical drain.

A new neurosurgical drain.


A new pneumatic transfer system for the Bryant-Symons "head and neck" radiotherapy unit.


A new prolonged-acting type of chlorpromazine: behavioral effects and prolonged actions on nerve membranes.


A nitrosoguanidine-induced cluster of linked mutations near the streptomycin locus of Streptococcus.


A new quantitative technique for the assessement of cerebrospinal fluid absorption in man.


A note on the evolution of gamete dimorphism.


A note on the use of xylazine hydrochloride (Rompun, Bayer) in a black wildebeest.


A novel antimitogenic principle detected in human liver.


A novel fragmentation in the mass spectra of some 3-(2-hydroxyphenyl)-4-oxo-3,4-dihydroquinazolines.


A novel approach to the questions of allosteric properties or a 'receptor reserve' of drug binding sites of intestinal smooth muscle cells.


A novel substrate for prenyltransferase. Formation of a nonallylic cis-homofarnesyl pyrophosphate.


A novel technique for the study of dry process membranes during their nascent phases.


A partnership: child care in a New Zealand suburb.


A pack for the emergency treatment of malignant hyperpyrexia.


A pharmacokinetic slide rule for more accurate drug treatment.


A phenylethylamine oxidising defect in migraine.


A piezoelectric fine-focusing optical mount.


A phytochemical investigation of the leaves of Aristolochia elegans.


A pharmacological study of the adrenergic mechanisms involved in the stretch reflex of the decerebrate rat. 1 The effects of catecholamine precursors, enzyme inhibitors, and monoamine depletors have been studied on the stretch reflex in the decerebrate rat.2L-DOPA alone had a biphasic effect, facilitation followed by inhibition and recovery of the reflex.3 About 10% of the preparations did not develop decerebrate rigidity. These preparations did not have a stretch reflex. Within 1 to 5 min of the injection of L-DOPA in these inactive preparations, a stretch reflex could be elicited.4 Control experiments indicate that L-DOPA was acting centrally after decarboxylation.5DL-dihydroxyphenylserine had an inhibitory effect, without a preceding facilitation.6 When L-DOPA was preceded by diethyldithiocarbamate (i.v.) or FLA-63 (i.p.), the predominant response was a sustained facilitation, without an accompanying inhibition.7 It is concluded that in the decerebrate rat, increased stretch reflex activity is associated with increased central levels of dopamine, and decreased stretch reflex activity with increased central levels of noradrenaline. The results are discussed with reference to the possibility that dopamine acts by liberating 5-hydroxytryptamine.


A pilot study of clinical internship training at the William S. Hall Psychiatric Institute.


A possible case of inherited abnormalities in the central nervous system of calves by an AI sire.


A problem-solving oral examination for family medicine.


A preliminary study of the elimination of the internship. A comparative study of performance of internship- and noninternship-trained residents in a psychiatric inpatient setting.


A possible role for prolactin in control of steroid secretion by the human Graafian follicle.


A punch drunk profession.

A punch drunk profession.


A proposed solution for the determination of the ionization constants of sets of ionizinggroups in proteins.


A quantitative approach to the effects of the plerocercoid of Schistocephalus solidus Müller 1776 on the ovarian maturation of the three-spined stickleback Gasterosteus aculeatus L.


A radioimmunoassay for a procine intestinal calcium-binding protein.


A rapid and efficient method of radioactively labeling L-asparaginase.


A rapid radioimmunoassay method for the detection of hepatitis B antigen.


A rapid reliable method of labeling Sn-MAA with 113mInCi3.


A real time picture processor for use in biologic cell identification. I. System design.


A real time picture processor for use in biologic cell identification. II. Hardware implementation.


A reconsideration of psychodynamic mechanisms in psychosomatic symptom formation in view of recent clinical observations.


A perspective on drug reaction reporting.


A recursive-nonrecursive factor model and developmental causal networks.


A respiratory syndrome in cattle resulting from thrombosis of the posterior vena cava.


A review of chest X-rays of central Australian aboriginal infants and children.


A review of the health hazards from copper exposure.


A role for chloride in the autoxidation of hemoglobin under conditions similar to those in erythrocytes.


A sample evaluation of education in clinical chemistry.


A role for recBC nuclease in the distribution of crossovers along unreplicated chromosomes of phage lambda.


A scanner for the absorption optical system of the analytical ultracentrifuge based on a vidicon television camera.


A scale for predicting subsequent suicidal behaviour.


A second example of anti-Yta with rapid in vivo destruction of Yt(a plus) red cells.


A segregation analysis of the association of haptoglobin types and ABO blood groups.


A sensitive assay for human enterokinase and some properties of the enzyme.


A serological survey on group A and B arbovirus antibodies in Libya.


A significant increase in larval resistance of Lucilia cuprina Wied. to diazinon.


A simple and inexpensive restraining cage for rats.


A simple dual detector stand for clinical use.


A simple method for combustion of faecal samples prior to liquid scintillation counting.


A simple enzymic synthesis of 5'-terminal inosine-containing dinucleosides.


A simple method of injecting dangerous or fractious animals using an automatically emptying syringe.


A simple total synthesis of (plus or minus)-dendrobine.


A simple radiochemical assay for prostaglandin synthetase.


A simple, rapid thin-layer chromatographic drug screening procedure.


A second heterothallic Aspergillus.

A second heterothallic Aspergillus.


A simplified bioassay for organophosphate detoxification and interactions.


A single-channel FM telemetry unit: its design, fabrication and application.


A simplified method for cyanogen bromide activation of agarose for affinity chromatography.


A single-step procedure for inducing partial tolerance of DNCB in human subjects.


A specific gas chromatographic method for the determination of dyphylline in serum.


A specifically encapsidated fragment from the RNA of tobacco mosaic virus: sequence homology with the coat protein cistron.


A spectrophotometric method for the determination of traces of nitrate. Application to water analysis.


A sporadic case of presumed Pelizaeus-Merzbacher disease.


A statewide approach to graduate medical education.


A statistical comparative study of the basilar impression in syringomyelia.


A steady-state kinetic investigation of the uricase reaction mechanism.


A strategy for developing educational objectives in medicine: problem-solving skills.


A structured interview for use by psychology technicians.


A study of bladder catheterization with inguinal hernia operations.


A study of codeine metabolism.

A study of codeine metabolism.


A single-crystal ultrasonic catheter-tip velocity probe.


A study of joint disease in granuloma annulare.


A study of patients attending the casualty department of a paediatric hospital.


A study of the active center of trypsinogen by comparative affinity chromatography of trypsinogen, alpha-, beta-, psi-trypsins, DIP-trypsin, chymotrypsinogen, alpha-chymotrypsin and elastase.


A study of the applicability of the electron microprobe to a quantitative analysis of K and Na in single human red blood cells.


A study of the effects of nicotinic acid in cattle, with special reference to ketosis therapy.


A study of the family diet in a district in Cairo.


A study of the histamine H2-receptors in heart muscle and coronary vessels.


A study of the influence of pH on the buccal absorption and renal excretion of procainamide.


A study of urinary 17-ketosteroids in ovarian neoplasms.


A study of the prenatal and postnatal toxicity of a sulfydryl resin in rats.


A study on suicide.

A study on suicide.


A study of the sulfhydryl groups of rat brain hexokinase.


A study on vascular reconstruction by flow visualization.


A study protocol for evaluating the quality of pharmaceutical services.


A submaximal test for dogs: evaluation of effects of training, detraining, and cage confinement.


A surface microscope for clinical and laboratory use.


A sugar-dependent increase in red cell stability.


A survey of general practitioners' referrals to a psychiatric out-patient service.


A synthesis of aromatic steroids.

A synthesis of aromatic steroids.


A synthesis of tulipalin A and B and the acylglucoside, tuliposide A, fungitoxic agents from Tulipa gesneriana. Carbon-13 nuclear magnetic resonance analysis of anomeric configuration in acylglucosides.


A synthesis of racemic ipomeamarone and epiipomeamarone.


A system for data processing in haematology. The data processing problems which arise in the provision of a modern haematology service are discussed in the light of available resources, and the basic requirements of any automated data processing system are defined. The differences between the needs of haematology and those of other pathology specialities are emphasized. A strategy for the development of a simple system which covers data capture, analysis, and retrieval is described. Separation of the short-and long-term functions of the system provides a relatively simple, inexpensive solution which can be modulated to meet the particular circumstances of each laboratory.


A systematic approach for making a psychiatric diagnosis.


A technique for estimating the position of the oxygen-hemoglobin dissociation curve. A nomogram was constructed which allows estimation of the P(50) value from the Po(2) and per cent O(2) saturation of a single venous blood sample. There was excellent correlation between 50 estimated P(50) values obtained in 27 severely ill patients when compared with P(50) values determined from constructed OH-DC's (correlation coefficient 0.92). The mean of the differences between the estimated and determined P(50) values was 1.5 mm Hg with a standard deviation of +/-1.1, and the maximum difference was 4 mm Hg.


A technique for in situ repair of bipolar transvenous pacemaker electrode.


A technique for reinsertion of the displaced nephrostomy tube.


A technique for the handling and application of ixodid ticks to their mammalian host.


A theoretical analysis of some measures used in studies of small bowel propulsion and their dependence on gastric evacuation pattern.


A theoretical study of solvent effects on the conformational stability of acetylcholine.


A thin-layer chromatographic method for determining carbamazepine in blood.


A two-dimensional thin-layer chromatographic method for screening carbohydrate anomalies.


A tympanic membrane temperature measurement technique for birds.


A survey of bovine brucellosis in four districts of Uganda.


A unilateral memory defect.

A unilateral memory defect. Several authors have suggested that arousal is an important component of learning. If the neglect syndrome is a unilateral defect of alerting (arousal) as recent studies have suggested, then patients with this syndrome should have a unilateral learning defect. To test these hypotheses, eight patients with unilateral neglect were given consonant trigrams randomly to either ear, and the patients were asked to identify the auditory stimuli either immediately or after an 18 second delay during which time the patients were asked to count. All eight demonstrated that the number of errors between the delay and non-delay conditions was greater on the neglected side significance >0·01), thereby supporting these hypotheses.


A variation in rhytidectomy incision at the front of the ear.


A technique for improving esophageal and tracheopharyngeal speech.


A vasopressin analogue in treatment of diabetes insipidus.


A versatile minidisc module for a centrifugal analyzer.


A versatile restraining device for the unanesthetized cat.


A Bayesian approach to the recognition of discrete patterns with an application to a problem of protein molecular structure.


A 4-methoxybenzoate monooxygenase system from Pseudomonas putida. Circular dichroism studies on the iron--sulfur protein.


A 7-year follow-up study of ninety patients with psoriasis.


Abnormal serum isoenzyme of leucine aminopeptidase (LAP) in malignant neoplastic disease.


Abnormal patterns of mucus secretion in apparently normal mucosa of large intestine with carcinoma.


Abnormal kinetics of degranulation in chronic granulomatous disease.


Abnormal tail development in a cercaria of Schistosoma mansoni.


Abnormalities in clotting and thrombolysis as a risk factor for stroke.


Abnormalities of taste and smell after head trauma. Abnormalities of taste and smell were studied in 29 patients after head trauma. These abnormalities included decreased taste acuity (hypogeusia), a distortion of taste acuity (dysgeusia), decreased smell acuity (hyposmia), and a distortion of smell acuity (dysosmia). This syndrome can occur even after minimal head trauma and can begin months after the moment of injury. The patients exhibited a significant decrease in total serum zinc concentration (patients, 77 ± 3 μg/100 ml, mean ± 1 SEM, vs controls, 99 ± 2 μg/100 ml, P>0·001) and a significant increase in total serum copper concentrations (113 ± 4 μg/100 ml vs 100 ± 2 μg/100 ml, P<0·001) compared with control subjects. Symptoms of hypogeusia, dysgeusia, and dysosmia are frequent sequelae of head injury and are important to the patients and to their care after trauma.


Abnormality in tissue isoferritin distribution in idiopathic haemochromatosis.


Abolition by tetrodotoxin of the spontaneous fibrillation potentials of denervated skeletal muscle of rabbit. An in vivo comparative electromyographic study.


Abortifacient action of orally administered 16,16 dimethyl prostaglandin E2 and its methyl ester.


Abortion, 1973. Some recent world events in relation to pregnancy termination.


Absolute determination of atmospheric halocarbons by gas phase coulometry.


Absence of an ovary and uterine tube.

Absence of an ovary and uterine tube.


Absorption of digoxin from different oral preparations in normal subjects during steady state.


Absorption, distribution and excretion of 2,6-dichlorobenzylidene-aminoguanidine acetate.


Absorption, distribution and excretion of inorganic tin in rats.


Abuse and timing of use of antibiotics in acute otitis media.


Acantholytic keratosis.

Acantholytic keratosis.


Accessing the need for career guidance for nurses.


Abnormalities of respiratory gases in synovial fluid of patients with juvenile rheumatoid arthritis.


Acceleration phenomenon of granuloma formation caused by felt-pellet in rats.


Accumulation and washout of glycerol in isolated rabbit atria.


Accuracy of diagnosis in appendicitis.

Accuracy of diagnosis in appendicitis.


Absence of arteriovenous shunting in peripheral arterial disease.


Acetaminophen metabolism in man, as determined by high-resolution liquid chromatography.


Acetazolamide and potassium flux in red blood cells. Studies in patients with hyperkalemic periodic paralysis.


Acetylcholine synthesis from recaptured choline by a sympathetic ganglion. 1. The recapture and re-use of choline formed by the hydrolysis of released acetylcholine (ACh) was studied in the superior cervical ganglion of the cat using radioactive tracer techniques. The ganglion's ACh store was labelled by perfusion, during preganglionic nerve stimulation, with Krebs solution containing [(3)H]choline.2. Preganglionic stimulation (5 Hz for 20 min) of ganglia containing [(3)H]ACh released similar amounts of radioactivity when perfusion was with neostigmine-choline-Krebs or with hemicholinium-Krebs. This indicated that neostigmine does not increase transmitter release.3. The amount of radioactivity collected from stimulated ganglia during perfusion with choline-Krebs was 39% of the amount of radioactivity collected during perfusion with medium containing neostigmine or hemi-cholinium. This difference in release was almost (85%) accounted for at the end of the experiment by extra radioactive ACh in the ganglia perfused with choline-Krebs. It is concluded that during preganglionic nerve stimulation approximately 50-60% of endogenously produced choline is recaptured for ACh synthesis; thus, during activity preganglionic nerve terminals appear selectively to accumulate choline.4. However, chronically decentralized ganglia accumulated as much choline as did acutely decentralized ganglia, and this was interpreted as indicating that at rest preganglionic nerve terminals do not selectively accumulate choline.5. Increased exogenous choline concentration increased the amount of radioactivity collected during nerve stimulation in the absence, but not the presence, of an anticholinesterase agent. The spontaneous efflux of radioactivity was little affected by changes in external choline levels. It is concluded that exogenous choline and choline made available from released transmitter compete for uptake into nerve terminals.


Acetylcholine uptake: lack of association with cholinergic neurons.


Acetylcholinesterase-staining synaptosomes from rat hippocampus: relative frequency and tentative estimation of internal concentration of free or 'labile bound' acetylcholine.


Acid alpha-glucosidase from human gastrointestinal mucosa--separation and characterization.


Acid response to graded doses of pentagastrin and feeding, and effect of atropine in Heidenhain pouch cats.


Acid-base balance of cerebrospinal fluid in acute uncompensated metabolic acidosis of infancy.


Acoustic reflex relaxation to identify sensorineural hearing impairment.


Acoustic tuning of single cells in middle suprasylvian cortex of cat.


Acquired agammaglobulinaemia in familial disgammaglobulinaemia: effects of splenectomy.


Actinomycin D and RNA transport.

Actinomycin D and RNA transport.


Actinobacillus suis infection in pigs. A report of four outbreaks and two sporadic cases.


Action of horse radish peroxidase upon some falvones.


Actions of prolactin and frusemide on cardiac rate and rhythm.


Activation by diphenylthiohydantoin of inhibitory influences on spinal motor activity.


Activation of ethanol metabolism by 2,4-dinitrophenol in the isolated perfused rat liver.


Actions of GABA, picrotoxin and bicuculline on adrenal medulla.


Activation of preexisting messenger RNA in dry pea embryo axes.


Activity and job-responsibility as measured by judgment behaviour in myocardial infarction patients.


Activity group parameters.

Activity group parameters.


Activity of some tetrahydro- and pyrazinoquinolines against early developing forms of Schistosoma mansoni.


Acute adrenal hemorrhage complicating anticoagulant therapy.


Acute dehydrating gastro-enteritis in undernourished infants. The diagnosis and correction of electrolyte and metabolic abnormalities.


Acute effect of benzene on 59Fe incorporation into circulating erythrocytes.


Acute effects of cadmium on proximal tubular function in rabbits.


Acute experiments on neuroeffector function in canine esophageal achalasia.


Acute hepatotoxicity of tannic acid added to barium enemas.


Acute heroin withdrawal in Viet Nam. An immunochemical evaluation of excretion.


Acute hexachlorophene encephalopathy: clinico-neuropathological correlation.


Acute hypercapnia and brain energy state in sustained hyperammonaemia.


Acute intestinal obstruction in childhood.


Acute nasal sinusitis.

Acute nasal sinusitis.


Acute parathyroid hormone response: sensitivity, relationship to hypocalcemia, and rapidity.


Acute proptosis from hemorrhage into a maxillary sinus mucocele.


Acute renal failure after intravenous urography: detection of antibodies against contrast media.


Acute renal failure following potassium ferrocyanide poisoning treated with peritoneal dialysis.


Acute renal failure in multiple myeloma. Two cases of acute renal failure complicating multiple myeloma are reported. In both, the renal failure preceded the diagnosis of multiple myeloma. In one case oliguria occurred after performance of a venogram; renal function returned to normal after two weeks of intermittent peritoneal dialysis, emphasizing the reversibility of the renal failure in some cases.


Acute systemic immediate hypersensitivity in the pig.


Acute renal failure in the rat after folate intoxication: diagnostic value of lactate dehydrogenase and alkaline phosphatase measurements in serum and urine.


Acute vascular injuries of the upper extremity.


Acute, subacute and 23-day chronic marihuana inhalation toxicities in the rat.


Acylation of glycerol-3-phosphate by rabbit heart mitochondria and microsomes: triiodothyronine-induced increase in its activity.


Acylation of monoglycerides by locust fat-body microsomes.


Addition of thioglycolic acid to stendomycin.


Adaption of UCG-Lyphotest--a hemagglutination inhibition pregnancy test with human serum or plasma.


Additional examinations in lymphography: a radiological-surgical-pathological correlation.


Additional notes on the biology of the Bahamian hutia, Geocapromys ingrahami.


Additive erythemogenic effects of middle-(280-320 nm) and long-(320-400 nm) wave ultraviolet light.


Adenocarcinoma in a uterus duplex.

Adenocarcinoma in a uterus duplex.


Adenocarcinoma in the nasal cavity and brain of a dog.


Adenovirus DNA replication. I. Requirement for protein synthesis and isolation of nuclear membrane fractions containing newly synthesized viral DNA and proteins. Nuclear membrane fractions were prepared by two procedures from KB cells pulse labeled with [(3)H]thymidine for 5 min late after infection with adenovirus 2: (i) the M-band technique, which yields a sharp peak containing most of the newly synthesized viral DNA, and (ii) the discontinuous sucrose gradient method, which yields three membrane fractions, one which bands at the interface between sucrose layers at density 1.18 and 1.20 g/ml and contains most of the newly synthesized viral DNA. Studies using cycloheximide to inhibit protein synthesis showed that proteins whose synthesis begins early after infection and occurs in the absence of viral DNA replication are required for viral DNA synthesis late after infection. To study the nature of these proteins, nuclear membrane fractions were isolated from cells labeled with [(3)H]leucine from 6 to 24 h postinfection in the presence of arabinosyl cytosine to block viral DNA replication, and were analyzed by electrophoresis in sodium dodecyl sulfate polyacrylamide gels. Two proteins of molecular weights 75,000 and 45,000 were the major labeled polypeptides in the nuclear membrane fractions prepared from infected cells both by the M-band and the discontinuous sucrose gradient methods. These two proteins were not found in nuclear membrane fractions from uninfected cells. It is suggested that the 75,000 and 45,000 proteins may be early viral gene products that may play a role in the viral DNA replication.


Administration of human chorionic gonadotrophins (HCG) to pregnant pony mares.


Administration, labelling and general principles of drug prescription in the elderly.


Admission policies to Australian medical schools.


Adrenergic influence on the internal urinary sphincter.


Adriamycin.

Adriamycin.


Adsorption of halothane by activated charcoal. Further studies.


Adsorption of fibrinogen-125I on Stellite 21. Study with polished and Teflon-covered surfaces.


Adult nutritional osteomalacia in Black patients.


Advanced colon cancer: review of 123 cases at University of Mississippi Medical Center, 1966-1969.


Adolescents and education for living.

Adolescents and education for living.


Adenyl cyclase activity in developing rat heart.


Advances in psychiatry. 7. Schizophrenia.


Advances in psychiatry. 8. Organic disorders.


Adrenergic mechanisms in cerebral blood vessels: effect of tyramine on the isolated middle cerebral artery of the goat.


Advances in psychiatry. 9. Senile disorders.


Adverse drug reaction in the elderly.

Adverse drug reaction in the elderly.


Aerobic and anaerobic surgical wound contamination in patients with cancer.


Afferent fibers with multiple encoding sites.


Advances in high-speed motion picture photography of the larynx.


Affinity chromatography of Sorghum acid protease.


Afferent fibres from pulmonary arterial baroreceptors in the left cardiac sympathetic nerve of the cat. 1. Afferent discharges were recorded from the left cardiac sympathetic nerve or the third sympathetic ramus communicans of anaesthetized cats. Twenty-one single units with baroreceptor activity were obtained.2. The receptors of each unit were localized to the extrapulmonary part of the pulmonary artery, determined by direct mechanical probing of the wall of the pulmonary artery after death of the animals. Conduction velocity of the fibres ranged from 2.5 to 15.7 m/sec.3. Afferent discharges occurred irregularly under artificial ventilation. The impulse activity was increased when pulmonary arterial pressure was raised by an intravenous infusion of Locke solution, or by occlusion of lung roots, and decreased by bleeding the animal from the femoral artery.4. Above a threshold pressure, discharges occurred synchronously with the systolic pressure pulse in the pulmonary artery. A progressive further rise in pressure did not produce an increase in the number of impulses per heart beat. Occlusion of lung roots initially elicited a burst of discharges but the number of impulses for each cardiac cycle gradually decreased.5. The receptors responded to repetitive mechanical stimuli up to a frequency of 10/sec, but failed to respond to stimuli delivered at 20/sec.6. The results provide further evidence for the presence of afferent fibres in the cardiac sympathetic nerve. These afferent fibres are likely to provide the spinal cord with specific information only on transient changes in pulmonary arterial pressure.


Affinity chromatography on an homologous series of immobilised N6-amega-aminoalkyl AMP. The effect of ligand--matrix spacer length on ligand--enzyme interaction.


Age as a political issue.

Age as a political issue.


Age dependent sensitivity to monosodium glutamate inducing brain damage in the chicken.


Age gradient in blood glucose levels. Magnitude and clinical implications.


Affinity labelling of isoelectrofocused fractions from a DNP antibody preparation with the photoactive labels 2,4-dinitrophenyl-1-azide and 2,4-dinitrophenyl-epsilon-aminocaproyldiazoketone.


Age of breeder versus hatchability of fertile eggs in Coturnix quail.


Age-dependent polydipsia in the SWR-J mouse.


Ageing and memory loss--role of experimental psychology.


Age-sex differences in response to antidepressant drugs.


Aggregates formed by mixtures of embryonic neural cells: activity of enzymes of the cholinergic system.


Aggression: culture and psychosomatic medicine.


Aging and individual differences: a longitudinal analysis of social, psychological, and physiological indicators.


Aging versus growth.

Aging versus growth.


Airborne-particle deposition in the respiratory tract of chickens.


Alcohol and drug abuse: causes of sudden death.


Alcohol consumption before myocardial infarction. Results from the Kaiser-Permanente epidemiologic study of myocardial infarction.


Alcohol susceptibility and plasma dopamine beta-hydroxylase activity.


Alignment of partial denaturation maps of circularly permuted DNA by computer.


Alcoholism in the United States.

Alcoholism in the United States.


Alkaloids of Tylophora species from Sri Lanka.


Alkaloids of Vinca species. 3. Isolation and characterization of indole alkaloids from Vinca libanotica.


Alleviative treatment in twin pregnancies. Is selection based on clinical diagnosis prudent?


Akinetic mutism in Wilson disease.

Akinetic mutism in Wilson disease.


Allograft cardiac valves. A view through the scanning electron microscope.


Alpha 1--greater than 2 fucosyltransferase of human bone marrow.


Alpha- and beta-adrenergic receptor blockade in the treatment of hypertension.


Alteration of in vivo glucose metabolism by cobaltous chloride.


Allescheria boydii: wild type and a variant from human pulmonary allescheriasis.


Alterations in hepatocytes after manipulation of the diet: copper, zinc and cadmium interactions.


Alterations of enzymes by riboflavin and by bromophenol blue during preparative disc-electrophoresis.


Alternans of loud midsystolic clicks: a unique finding in massive pericardial effusion.


Alternate menu patterns--survey and nutritional guidelines.


Altitude, migration, and fertility in the Andes. In order to examine the relationship between hypoxia and reduced fertility of high Andean populations, a sample of 241 females living in the low-altitude Tambo Valley of Peru was studied.  63 of the subjects were born in the low-altitude valley, 121 were migrants from high altitudes, and 57 were migrants born in low altitudes.  The rate of abortion was low among high-altitude subjects before they migrated, but became greater after migrating.  It was found that the high-altitude populations had almost twice as long parity intervals than the low-altitude populations.  Compared to migrants born at low altitudes, the high-altitude-born subjects who migrated to low altitudes had higher fertility rates.  The results of the study are consistent with the hypothesis that high altitudes, through anoxia, have a lowering effect on fertility.  Of the several possible explanations which might account for the increase in fertility of downward migrants on migration from high to low altitude (migration, socioeconomic factors, acculturation, seasonal male emigration from high altitude,  and removal of hypoxia stress), altitude appears to be the most significant.


Amantadine toxicity in a patient with renal insufficiency.


Amebic hepatic abscess.

Amebic hepatic abscess.


Ameloblastoma of mucosal origin. A pathobiologic reevaluation.


American Board of Internal Medicine. Changes in policies related to admission to examination.


Amenorrhea in endogenous depression.

Amenorrhea in endogenous depression.


Amino acid analysis--peak integration and identification by computer.


Amino acid metabolism in acute renal failure: influence of intravenous essential L-amino acid hyperalimentation therapy. A solution of 8 essential I-amino acids and hypertonic dextrose was administered to 5 patients in acute postoperative renal failure in a program of hyperalimentation designed to decrease the patient's catabolic state and to accrue certain metabolic benefits. A sixth patient receiving intravenous glucose alone served as a control. The pretreatment plasma concentrations of amino acids in all 6 patients did not differ significantly from normal; following intravenous essential amino acids at a dose of approximately 12.6 gm/24 hours, no significant elevations out of the normal range of these substances occurred. Since urinary excretion rates did not dramatically increase, urinary loss was excluded as a possible cause for the failure of increase of plasma concentrations. The results suggest that the administration of an intravenous solution of 1-amino acids and hypertonic dextrose is associated with rapid clearance from the blood of these substances and, with a failure of increased urinary excretion, indirect evidence of amino acid utilization for protein synthesis has been obtained. Histidine supplementation in patients with acute renal failure is probably unnecessary based on the lack of significant decreases in histidine concentrations in these patients.


Amino acid sequence of oxiana alpha, the main neurotoxin of the venom of Naja naja oxiana.


Amino acid sequence of the N-terminal 158 residues of rabbit muscle aldolase.


Aminoacyl derivatives of nucleosides, nucleotides, and polynucleotides. 18. Synthesis of 2'(3')-O-aminoacyl derivatives of dinucleoside phosphates.


Aminoacyl-tRNA synthetase complex from rat liver.


Aminoglycoside antibiotics. VI. Structure determination of 4'-deoxybutirosins (Bu-1975C1 and C2).


Ammonium chloride poisoning in chronic renal disease. A 58-year-old woman with a long history of renal stone disease and urinary tract infection presented to the emergency room with exhaustion and air hunger. Laboratory data confirmed profound metabolic acidosis. Unduly large quantities of bicarbonate and potassium were required for correction of the deficits. She had been taking 6 g daily of ammonium chloride as a urine-acidifying agent for a period of six months in addition to agents directed against urinary tract infection. The combination of impaired renal function and effective hydrogen ion loading resulted in profound systemic acidosis. The metabolic derangements associated with the administration of ammonium chloride and its use as a therapeutic agent are discussed.


Ampicillin in portal and peripheral blood and bile after oral administration of ampicillin and pivampicillin.


Amygdala functions within the alimentary system. The amygdaloid complex plays an important role in various defensive, sexual and metabolic functions of the organism. Our previous experiments on the defensive functions demonstrated that the amygdala may be divided into dorsomedial excitatory and basolateral inhibitory parts. Our recent experiments showed that this division is true also for alimentary mechanisms. The dorsomedial part of the amygdala acts as a facilitatory "center" and the lateral part as an inhibitory alimentary "center". These functions of the amygdala are parallel to those of the hypothalamic feeding centers. Bilateral damage to either the dorsomedial amygdala or to the lateral hypothalamus produced aphagia with adipsia, decrease of body weight and impairment of both classical and instrumental reactions. These changes were accompanied by low general arousal, atonia, catatonic like positions, negavitism and loss of positive emotional reactions. Damage to the lateral amygdala, on the other hand, produces a syndrome similar to damage to the ventromedial hypothalamus, i.e. hyperphagia and an increase of body weight. Slight increase of both classical and instrumental reactions and disinhibition of responses during intertrial intervals were found in both cases. Combined damage of the dorsomedial amygdala and lateral hypothalamus enhanced the symptoms attributable to each and prolonged the period of aphagia. Damage to the lateral amygdala subsequent to lesions of the dorsomedial amygdala and/or the lateral hypothalamus produced restoration of food intake, instrumental reactions and general arousal.


Amyloidosis and lung diseases.

Amyloidosis and lung diseases.


An acute non-surgical abdomen: Henoch-Schonlein's syndrome.


An additional trigeminal system in certain snakes possessing infrared receptors.


An anaesthetic instrument tray.

An anaesthetic instrument tray.


An analysis of blood and serum grouping tests in paternity studies.


An antibody in the serum of an MN patient which reacts with the M1 antigen.


An antipoverty delivery system model. Intervention strategies for families with children below the age of three years.


An applicant's evaluation of a medical house officership.


An appoach to studying Emergency Department utilization.


An artifact in measurement of ionized calcium concentration from a heparin preservative, benzyl alcohol.


An assessment of aging based on screening data.


An assessment of the exchangeability of water molecules in the interior of chymotrypsinogen in solution.


An attempt at determining probabilities in human scalp hair comparison.


An attempt to obtain infertile live worms in mice infected with Schistosoma mansoni.


An atypical human immunoglobulin G with deletions in both heavy and light chains. Studies of the conformation and the in vitro recombination of the isolated subunits.


An automated micromethod for the quantitative analysis of di- and polyamines utilizing a sensitive high pressure liquid chromatographic procedure.


An automated procedure for circular dichroism and optical rotary dispersion spectroscopy.


An attachment for the Dermo-jet suitable for use through a laryngoscope.


An automated technique for canine blood typing.


An autoradiographic study of DNA synthesis in adolescent and adult mouse forebrain.


An effect of spironolactone on urinary acidification in normal man.


An efficient method for fractional labeling of microspheres.


An economical method of comparing inhaled bronchodilators in reversible diffuse airways obstruction. With special reference to a beta-2 stimulant--salmefamol.


An electron microscope study of the dorsal cap of the inferior olive in the rabbit, with special reference to the pretecto-olivary fibers.


An electromyographic study of the pathological plantar response.


An electron microscope study of the time course of platelet nucleotide, calcium, and acid phosphatase secretion.


An elevated cadaverine content in the brain of dormant mice.


An energy-conservation site between H2O and DBMIB: evidence from msec delayed light and chlorophyll fluorescence studies in chloroplasts.


An epidemiologic evaluation of long-term methadone maintenance treatment for heroin addiction.


An epidemiological study of self-poisoning in Penarth (South Wales).


An epidemiological study of the mental health of Australian university students.


An esophageal cannula force-feeding technique.


An evaluation of absorbent granule kits for determining serum thyroxine concentration and free thyroxine index in the diagnosis of thyroid function.


An evaluation of the GlaucoTest screening tonometer.


An evaluation of the tumorigenicity of cyclophosphamide and urethan in newborn mice.


An excitatory action of substance P on cuneate neurones.


An exposure cabinet for autoradiography of thin layer chromatograms.


An experimental basis for environmental medicine.


An improved and simple leucocyte culture technique for chromosomal preparation in rabbits.


An improved model of lead-induced brain dysfunction in the suckling rat.


An improved procedure for preparing the n-butyl-trifluoroacetyl amino acid derivatives and its application in the study of radioactive amino acids from biological sources.


An improved toluene-triton-based liquid scintillation system for counting 14C-labeled compounds at ambient temperature.


An index to compare the performance of scintigraphic imaging systems.


An indirect haemagglutination test for detection of antibodies against Mycoplasma hyopneumoniae using formalinized tanned swine erythrocytes.


An inexpensive activity measuring device for small animals.


An inborn error of vitamin B12 metabolism associated with cellular deficiency of coenzyme forms of the vitamin. Pathological and neurochemical findings in one case.


An international study of breast cancer.


An introduction to enzyme kinetics.

An introduction to enzyme kinetics.


An overview of EPA's implementation of the Noise Control Act of 1972.


An outflow of acetylcholine from normal and regenerating ventral roots of the cat. 1. An outflow of acetylcholine (ACh) has been measured from cat ventral roots in situ and in vitro, using standard bio-assay techniques. The ACh was collected in chambers, filled with physiological solution containing anticholinesterase, which surrounded the root.2. The outflow fell rapidly at first and then progressively more slowly, taking several hours to fall to a level near the assay threshold. The outflow of ACh resulted from cutting a root or from such conventional manipulations as stretching the root or teasing apart root filaments. The outflow could occur either from the end of a root (following cutting) or from along the length of the root (following stretching or teasing). The outflow was only detected in the presence of an anticholinesterase.3. ACh was resynthesized by roots at a rate which was usually rapid enough to maintain their ACh content at its original level in spite of a considerable ACh outflow. In roots subjected to a minimum of interference their ACh content built up to about twice the initial content after 5-7 hr soaking in eserinized Krebs solution although the total ACh outflow was equivalent to the original ACh content.Roots which were cut or stretched several times within a few hours put out a large amount of ACh and showed a fall in their ACh content below the initial level.4. The time course of sealing of the damaged ends of axons following crushing was assessed by measuring the injury potential for 1-2 hr after crushing at room temperature; in normal roots the half-time for decline of the injury potential was 91 +/- 10 min. This was slower than the rate of decline of the ACh outflow.5. An explanation for the observed outflow of ACh is discussed in terms of diffusion of ACh and sealing of axon ends. It is concluded that much of the ACh in normal ventral root axons is present in a readily diffusible form.6. Similar experiments on roots regenerating 9-10 days after crushing showed that the ACh outflow from regenerating roots was much smaller than from normal axons, although their ACh content was similar. This could have been due to more rapid sealing of the cut regenerating axons since the half-time for the decline of the injury potential following crushing of the regenerating axons was less than half that in control roots. The alternative possibility is considered that a high proportion of the ACh might be much less diffusible than in normal axons.7. The subcellular distribution of ACh in normal and regenerating peripheral axons is discussed.


An oxygen enrichment attachment for use with humidified air.


An ultrastructural study of balloon cell nevus. Relationship of mast cells to nevus cells.


An unusual case of congenital presence of blood in the lens.


An Australian national health scheme.

An Australian national health scheme.


An 18-month study of the parasitologic and tumorigenic effects of hycanthone in Schistosoma mansoni-infected and noninfected mice.


An improved technique for x-ray image evaluation. The two dimensional modulation transfer function.


Anaerobic excretion of fermentation acids by Hymenolepis diminuta during development in the definitive host.


Anaerobic bacteria and deconjugated bile salts in the upper small intestine of infants with gastrointestinal disorders.


Anaesthesia in mass tubectomy camp at high altitudes.


Analysis of a self-actualization scale: the POI.


Analysis of field potentials elicited in the dorsal column nuclei by splanchnic nerve A-beta afferents.


Analysis of old samples of Cannabis sativa L.


Analysis of papers in major cancer research journals.


Analysis of radiation exposures on or near uranium mill tailings piles.


Analysis of relative survival and proportional mortality.


Analysis of repeating DNA sequences by reassociation.


Analysis of the rate of ischemic injury in rat kidney utilizing survival statistics.


Analysis of ABO mating type frequencies.


Analytical study of two diazotization-coupling reactions. Application to the determination of nano-amounts of nitrite in water.


Anaphylaxis-like reactions to corticosteroid therapy.


Anatomy of an identified serotonin neurone studied by means of injection of tritiated 'transmitter'.


Anesthetic patch for painful procedures such as minor operations.


Angina pectoris with syncope due to paroxysmal atrioventricular block: role of ischaemia. Report of two cases.


Angioendotheliomatosis of the central nervous system.


Angiography in pelvic trauma.

Angiography in pelvic trauma.


Ankylosing spondylitis.

Ankylosing spondylitis.


Angiomyolipomas in a case of lymphangiomyomatosis syndrome: relationships to tuberous sclerosis.


Annual discourse--The dollars and sense of medical care and health services: relation.


Antagonism by folic acid of presynaptic inhibition in the rat cuneate nucleus. Folic acid applied topically in solution to the rat cuneate nucleus reduced presynaptic inhibition produced by peripheral stimulation. This resembles the action of picrotoxin in the same animals and it is possible that these two convulsants are acting in a similar manner by blockade of the receptors for the presynaptic inhibitory transmitter.


Antamanide. Relaxation study of conformational equilibria.


Antamanide. Dynamics of metal-complex formation.


Anterior approach to scoliosis. Results of treatment in fifty-one cases.


Anti-glaucoma microsurgery.

Anti-glaucoma microsurgery.


Anti-inflammatory properties of furobufen.


Anti-Lu 11: another antibody defining a high-frequency antigen related to the Lutheran blood group system.


Antibiotic sensitivity testing: a modification of the Stokes method using a rotary plater.


Antibiotic X-5108. 8. Absolute stereochemistry of antibiotic X-5108 and mocimycin.


Antibody response by murine bone marrow cells stimulated in vitro against soluble immune complexes.


Antibody to hepatitis B antigen in haemophiliacs and their household contacts. The prevalence of antibody to hepatitis B antigen, detectable by radioimmunoassay, was found to be no higher among 58 long-term household contacts of multiply transfused haemophiliacs than among 100 randomly chosen blood donors. This suggested that such contacts do not have greater exposure to serum hepatitis virus than that occurring through natural means. Among those persons possessing antibody, the multiply transfused haemophiliacs showed a marked tendency for higher antibody titres than their contacts, implying differences in pathogenesis between infection acquired through multiple transfusion and infection acquired naturally.


Antibody-mediated immunity in the presence of Mirex and DDT.


Anticoccidial activity of Lasalocid (X-537A) in chicks.


Anticonvulsant activity and monoamine oxidase inhibitory properties of 1,3,5-trisubstituted pyrazolines.


Anticonvulsant activity of substituted 4-thiazolidones.


Anticonvulsant activity of 1-alkyl-4-substituted 3,5-pyrazolidinediones.


Anticonvulsant properties of cannabidiol.


Anticonvulsant effects of cannabinoids in mice: drug interactions within cannabinoids and cannabinoid interactions with phenytoin.


Antigen-antibody crossed electrophoresis of rat brain synaptosomes and synaptic vesicles: correlation to water-soluble antigens from rat brain.


Anticholinesterase and hypotensive effects of some intravenous contrast media.


Antigen-induced suppression of agglutinins following the repeated high dose administration of bacteria (Pseudomonas species) at various ages.


Antigenicity of p-azobenzenearsonate-containing oligopeptides in rabbits.


Antihypertensive efficacy of metolazone.


Antimetabolites produced by microorganisms. X. L-2-amino-4-(2-aminoethoxy)-trans-3-butenoic acid.


Antimitotic effects of hydroxyurea and its derivatives: structure-activity relationships.


Antithrombin 3 deficiency in maturity onset diabetes mellitus and atherosclerosis.


Antitumor agents. 8. Synthesis and cytotoxic activity of O,O'-bis(acrylyl)-alpha,omega-alkanediols.


Antler shedding by white-tailed deer in the Midwest.


Antler tentacles of Biomphalaria glabrata: genetic studies.


Aortic stenosis. Vagaries in diagnosis in the adult.


Anxiety reactions to marathon group therapy.


Aorticopulmonary fistula following repair of coarctation of the aorta.


Aplastic anemia.

Aplastic anemia.


Aorticopulmonary septal defect and interrupted aortic arch: a diagnostic challenge.


Apollo space crew cardiovascular evaluations.


Apparatus for batch analysis of sheep urine for methylmalonic acid.


Appearance of (14C)O in expired air and incorporation of 14C in hemoglobin after administration of glycine-2-(14C) in man.


Appearance of atrial rhythm with absent P wave in longstanding atrial fibrillation.


Antigenic study of Nicotiana tabacum and research on precipitins against tobacco antigens in the serum of smokers and nonsmokers.


Appearance of the distal esophagus following pneumatic dilation.


Appendicular dyspepsia due to stones (foreign body).


Application of argentimetric titration in semimicro estimation of some reducing sugars. 1.


Application of induced optical activity to the study of protein denaturation.


Application of mercurimetric titration in semimicro estimation of some sugars. 2.


Appointment book: growth by greater availability and proper scheduling.


Appraisal of sinus nodal recovery time in patients with sick sinus syndrome.


Are controls a "necessary evil"?

Are controls a "necessary evil"?


Arctic medicine in the Nordic countries. Aspects of the scope of Arctic medicine and some current research problems.


Are we winning the war against drug addiction?


Arginase in Chang's liver cells.

Arginase in Chang's liver cells.


Argininosuccinic aciduria: perinatal diagnosis and early dietary management.


Arterial and venous thromboembolism: kinetic characterization and evaluation of therapy.


Arterial assessment by Doppler-shift ultrasound.


Arteriovenous fistula following brachial arterial puncture for cerebral angiography.


Arterial embolism of tumor causing fatal organ infarction.


Arteriovenous malformation of the cerebellum: a case report and its medicolegal implications.


Arthritis and drug abuse.

Arthritis and drug abuse.


Arterioventricular relations and their classification. Two specimens of arterioventricular discordance and review of published reports.


Arthropod parasites of the brown-headed cowbird, Molothrus ater ater, in Ohio.


Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes.


Aryl hydrocarbon hydroxylase activity induced by cannabis resin: analysis for polycyclic hydrocarbons.


Ascorbic acid deficiency and fistula formation in regional enteritis.


Aseptic management of the obstructed kidney.


Aspects of amino acid metabolism and nutrition in the ectoparasitoid wasp, Exeristes roborator.


Aspartic acid as a precursor for glycine: (14C)glycine contamination of (14C)-aspartate prepared by the supplier at levels much greater than indicated.


Aspects of bonding failure: the psychopathology and psychotherapeutic treatment of families of battered children.


Aspects of plastic surgery. Cleft lip and palate--general.


Aspects of rewarming newborn infants with severe accidental hypothermia.


Aspiculamycin, a new cytosine nucleoside antibiotic. I. Producing organism, fermentation and isolation.


Aspergillosis: comparative virulence, metabolic rate, growth rate and ubiquinone content of soil and human isolates of Aspergillus terreus.


Aspects of the epidemiology of diverticular disease and ischemic heart disease.


Aspiculamycin, a new cytosine nucleoside antibiotic. II. Physico-chemical properties and structural elucidation.


Aspiculamycin, a new cytosine nucleoside antibiotic. 3. Biological activities, in vitro and in vivo.


Aspiration needle biopsy of thoracic lesions: an assessment of 227 biopsies.


Aspirin, indomethacin, catecholamine and prostaglandin interactions on rat arterioles and rabbit hearts.


Assay and characterization of polyanion--immunoglobulin complexes in sera of New Zealand Black mice.


Assay and purification of Met-tRNA hydrolase from rabbit reticulocytes.


Assay of glucose oxidase by differential conductivity.


Assay and isolation of a 40 S ribosomal subunit-Met-tRNAfMet binding factor from rabbit reticulocytes.


Assay of ovalbumin mRNA in reticulocyte lysate.


Assay of topical corticosteroids by suppression of experimental inflammation in humans.


Assay of urinary enzymes in toxic nephropathy.


Assessment of four methods for the determination of pseudocholinesterase activity.


Assessment of neurotic symptoms in Irish female patients.


Assessment of left ventricular function following coronary bypass surgery: a non-invasive study.


Assessment of physiological integrity of sonicated retinal rod membranes.


Assessment of the mutagenic properties of diquat and paraquat in the murine dominant lethal test.


Assessment of therapeutic equivalence in drug registration and control.


Assessment of the role of brush-border peptide hydrolases in luminal disappearance of dipeptides in man.


Assessment of therapy in psychogeriatric illness.


Association between paranasal sinusitis and bronchial asthma.


Association of glycoproteins with the membranes. I. Isolation and molecular weight of the monomeric unit of the major glycoprotein from human erythrocytes.


Association of glycoproteins with the membranes. II. Isolation and partial characterization of "lipophilic fragment" from human erythrocyte membrane glycoprotein.


Asthma and air pollution in two inner city areas in New York City.


Asthma--treatment with the aerosol steroid beclomethasone dipropionate.


Asymmetrical changes in the tertiary structure of alpha-chymotrypsin with change in pH.


Asymmetry of the particles of cellular membrane.


Asymptomatic liver disease in hepatitis B antigen carriers. Thirty-four healthy blood donors, found to be persistent HBAg carriers, have been investigated by means of serial liver function tests, bromsulphthalein (BSP) retention, and liver biopsy. Thirty-one of the donors had histological abnormalities including one with cirrhosis, three with chronic aggressive hepatitis, and 11 with chronic persistent hepatitis. In 13 biopsies there were focal areas of necrosis in the liver parenchyma. Serial liver function tests revealed abnormalities in each of the donors with cirrhosis or with chronic aggressive hepatitis, in seven of the 11 donors with chronic persistent hepatitis, and in seven of the 13 with focal parenchymal necrosis. The degree of BSP retention was greatest (>11%) in the donors with chronic aggressive hepatitis. The severity of the histological changes was related neither to the titre of the antigen in the serum nor to the presence of autoantibodies.


Atresia of the external auditory meatus.


Atrial receptor discharge during acute coronary occlusion in the dog.


Atresia of right pulmonary veins and anomalous left pulmonary venous drainage into portal circulation.


Atrial septal defect (secundum) associated with mitral regurgitation.


Atrophic gastritis and its sequelae. Results of 19-23 years' follow-up examinations.


Attempts to detect deoxyribonucleic acid from Agrobacterium tumefaciens and bacteriophage PS8 in crown gall tumors by complementary ribonucleic acid-deoxyribonucleic acid-filter hybridization. Labeled ribonucleic acid (RNA) complementary to Agrobacterium tumefaciens DNA and PS8 bacteriophage DNA (cRNA) were used in a systematic study of the sensitivity of cRNA/deoxyribonucleic acid (DNA)-filter hybridization for detection of small amounts of phage or bacterial DNA immobilized on filters. A. tumefaciens cRNA of specific activity 10(6) to 2 x 10(6) counts per min per mug reacted to a significant extent when the DNA-filter contained 1% A. tumefaciens DNA in a salmon DNA background, but 0.1% A. tumefaciens DNA was not detectable. PS8 phage cRNA of the same specific activity reacted to a significant extent when the DNA-filter contained as little as 0.01% PS8 DNA in a salmon DNA background. Both kinds of cRNA were found to bind to tobacco crown gall tumor DNA-filters. Similar reaction was found with control normal callus DNA-filters but not with tobacco seedling DNA-filters. The "hybrids" formed by cRNA with normal callus and tumor DNA-filters had low thermal stability. Attempts to purify the tumor and normal callus DNA prior to immobilization on the filter resulted in elimination of this spurious binding. No evidence was found for bacterial or phage DNA in crown gall tumor DNA.


Astro-therapy: a new modality in rehabilitation.


Attentional habituation and mental retardation. A theoretical interpretation of MA and IQ differences in problem solving.


Asymptomatic spondylodiscitis. An unusual feature of ankylosing spondylitis.


Attitude change.

Attitude change.


Attitude of the individual to his own body weight.


Atypical plasma cholinesterase, succinylcholine, and prolonged apnea.


Atypical chest pain with a peculiar cardiac configuration.


Attitudes towards social issues in medicine of five health science faculties.


Atypical ausculatory findings in patent ductus arteriosus and stenosis of the pulmonary artery branch.


Atypical proximal coarctation of the aorta: reconstruction by means of a heparin-coated temporary shunt bypass. Coarctation of the aorta may be found proximal to or involving the left subclavian artery. In this situation, adequate collateral may not be present, making aortic occlusion unduly dangerous. Simple and effective bypass protection can be achieved with a heparin-coated temporary shunt as illustrated in two patients described in this report.


Au-antigen positivity an autoimmune phenomon?


Augmentation of wound strength by pretreatment with epinephrine.


Augmentation of arterial hepatic and renal flow by extracted and synthetic parathyroid hormone.


Augmented urinary dilution following administration of tolinase in man.


Australian medical graduates in 1972.

Australian medical graduates in 1972.


Australia and New Zealand pacemaker survey, 1972.


Automated analysis of riboflavin in multivitamin preparations.


Autolysis in Staphylococcus aureus: preferential release of old cell walls. The kinetics of release of old versus new cell wall in two strains of Staphylococcus aureus were studied during autolysis. In both strains the autolytic enzyme is an amidase. Cells were double labeled with (3)H and (14)C, and the distribution of radioactivity in the cell walls was monitored during autolysis. In all cases the rate of release of steady-state lable from peptidoglycan was significantly higher than that of pulse label. Identical results were obtained with whole cells or isolated cell walls. The results suggest that in S. aureus the old cell wall is preferentially released during autolysis.


Automated colour test apparatus.

Automated colour test apparatus.


Automated fluorescence analysis of perphenazine in dissolution rate testing of tablet formulations.


Automated peak discrimination and integration for nonflame atomic absorption analysis at nanogram levels.


Automated microsequence analysis in the presence of a synthetic "carrier".


Automatic mass-spectrometric analysis: preliminary report on development of novel mass-spectrometric system for biomedical applications.


Automatic recognition of irradiated chromosomes.


Automatic sample injector. Its application in the analysis of adenosine triphosphate.


Autonomy: a concept reconsidered.

Autonomy: a concept reconsidered.


Autoradiographic studies of dysplasia and carcinoma in situ in cervical cones.


Autosomal recessive inheritance in the mesomelic dwarfism of Campailla and Martinelli.


Avascular necrosis of bone in systemic lupus erythematosus.


Averaged electroencephalographic response to intensity modulated tone.


Avoidance of nuclear family relationships in schizophrenia.


Axillo-axillary bypass with cephalic vein for correction of subclavian steal syndrome.


Azathioprine for pemphigus and pemphigoid--a 4 year follow-up.


ABO blood groups and tuberculosis in North and East Greenlanders.


ATP, CP, and lactate concentrations in muscle tissue during exercise in male patients with tetralogy of Fallot.


B-chromosome behaviour in Phaulacridium vittatum.


B-scan ultrasonography in ophthalmology.


B-scanning and holography in ophthalmic diagnosis.


Bacteria and the etiology of colonic cancer.


Bacterial metabolism of para- and meta-xylene: oxidation of a methyl substituent. Pseudomonas Pxy was isolated on p-xylene as sole source of carbon and energy. Substrates that supported growth were toluene, p-methylbenzyl alcohol, p-tolualdehyde, p-toluic acid, and the analogous m-methyl derivatives, including m-xylene. Cell extracts prepared from Pseudomonas Pxy after growth with either p-xylene or m-xylene oxidized the p- and m-isomers of tolualdehyde as well as p-methylbenzyl alcohol. The same cell extracts also catalyzed a "meta" fission of both 3- and 4-methylcatechol. Treatment of Pseudomonas Pxy with N-methyl-N'-nitro-N-nitrosoguanidine led to the isolation of two mutant strains. Pseudomonas Pxy-40, when grown on succinate in the presence of p-xylene, accumulated p-toluic acid in the culture medium. Under the same conditions Pseudomonas Pxy-82 accumulated p-toluic acid and also 4-methylcatechol. When Pseudomonas Pxy-82 was grown on succinate in the presence of m-xylene, 3-methylcatechol and 3-methylsalicylic acid were excreted into the culture medium. A pathway is proposed for the initial reactions utilized by Pseudomonas Pxy to oxidize p- and m-xylene.


Bacterial metabolism of para- and meta-xylene: oxidation of the aromatic ring. Pseudomonas putida 39/D oxidized p-xylene to cis-3,6-dimethyl-3,5-cyclohexadiene-1,2-diol (cis-p-xylene dihydrodiol). The latter compound was isolated in crystalline form and its physical properties were determined. The cis configuration of the hydroxyl groups in the oxidation product was inferred from its ability to form an isopropylidene derivative with 2,2-dimethoxypropane. Acid treatment of cis-p-xylene dihydrodiol resulted in the formation of 2,5-dimethylphenol. A partially purified preparation of cis-toluene dihydrodiol dehydrogenase oxidized cis-p-xylene dihydrodiol to 1,2-dihydroxy-3,6-dimethylbenzene (3,6-dimethylpyrocatechol). P. putida 39/D oxidized m-xylene to a compound whose spectral and chromatographic characteristics were consistent with the structure 3,5-dimethyl-3,5-cyclohexadiene-1,2-diol. This product was very unstable, and all attempts to isolate it led to the formation of 2,4-dimethylphenol.


Bacteriology of aspiration pneumonia. A prospective study of community- and hospital-acquired cases.


Bacteriorhodopsin as an electrogenic proton pump: reconstitution of bacteriorhodopsin proteoliposomes generating delta psi and delta pH.


Baseline 24-hour plasma corticosterone rhythm in normal, sham-operated and septally-lesioned rats.


Basal gastric secretion in man. Control subjects and patients with myasthenia gravis.


Basal metabolic rate and lipid and liver glycogen in mice infected by the nematode Nematospiroides dubius.


Basic computer program for amino acid analysis data.


Bat ticks of the genus Argas (Ixodoidea: Argasidae). II. The structure and possible function of the ventral paired grooves in A. (Chiropterargas) boueti and A. (Carios) vespertilionis.


Behaviour therapy in a case of blepharospasm.


Benefits of hospitalization in rheumatoid arthritis.


Benzimidazolecarbamate methyl ester--evaluation of its effects in vivo and in vitro.


Beta-hydroxyhomomethionine and beta-hydroxymethoxinine: preparation and separation of diastereomers.


Bias and quality control in forensic science: a cause for concern.


Biennial Scientific Congress and 68th Annual General Meeting Unisa, Pretoria, 15-19 October, 1973. Presidential address.


Bifascicular block due to penetrating wound of the heart: electrophysiology studies.


Bilateral internuclear ophthalmoplegia. Association with occlusive cerebrovascular disease.


Bilateral lymphoepithelioma of the tonsils.


Bilateral nictitating membrane conditioning in rabbits under asymmetrical levels of cutaneous afferent activity.


Bilateral traumatic dislocation of hip joints.


Bilateral Morton's metatarsalgia in a child.


Bile duct pressure and cardiac symptoms.


Biliary atresia. New concepts of pathology, diagnosis, and management.


Biliary tract carcinoma associated with ulcerative colitis.


Binding of (3H)phlorizin to rat kidney plasma membranes.


Binding of antibody to LDH-X by the mouse blastocyst. 1.


Binding of cholinergic substances by proteolipids fractionated at -60 degrees C from quenched rat cerebral cortex.


Binding of certain acidic drugs to human albumin: theoretical and practical estimation of fundamental parameters.


Binding of concanavalin A-sepharose to glycoproteins of liver microsomal membranes.


Binding of folic acid activity (FAA) to proteins in mother's milk.


Binding of estradiol to macromolecules in the rat neurohypophysis: effects of time of the day, pinealectomy and melatonin administration.


Binding of oestradiol to rabbit blastocysts and its possible rôle in implantation.


Binding of quinidine to a red blood cell hemolysate preparation.


Binding of 2,4-dinitrophenyl compounds and other small molecules to a crystalline lambda-type Bence-Jones dimer.


Bioactive compounds in the aquatic environment: studies on the mode of uptake of DDE by the aquatic midge, Chironomus tentans (Diptera: Chironomidae).


Binding studies on isoelectrofocused fractions from a DNP antibody population.


Bioassay of a Drosophila pheromone influencing sexual selection.


Bioavailability and dissolution properties of two commercial digoxin tablets.


Bioavailability determination of two crystal forms of sulfameter in humans from urinary excretion data.


Bioavailability of organically bound iodine.


Bioavailability testing and clinical significance.


Bioavailability--a commentary.

Bioavailability--a commentary.


Bioavailability: a practitioner's point of view.


Biochemical effects of low (radium) and high dose rate (Cathetron) irradiation on the vaginal epithelium.


Biochemical observations on the cartilage of achondroplastic (can) mice.


Biochemical profiles of suburban, inner city, and neuropsychiatric patients.


Biochemical studies on some serum enzymes in cretins.


Biochemical responses of myocardial cells in culture to oxygen and glucose deprivation.


Biogenesis of beta-carotene in Mycobacterium kansasii. The biogenesis of beta-carotene in the photochromogen Mycobacterium kansasii consists of two reactions. The first reaction is photochemical, and is dependent on the wavelength of the incident light and on oxygen but is independent of temperature. The second reaction does not require illumination, and is dependent on the temperature and on oxygen. The latter, or dark reaction, requires the synthesis of new protein, and was shown to have the characteristics of an inducible system. Carotenogenesis was stimulated by incident light of wavelengths of 420, 540, and 650 nm. Immediately after illumination there was an increase in the synthesis of ribonucleic acid and beta-carotene accumulation started after a lag of 8 to 10 min. The synthesis of beta-carotene exhibited temperature dependence with an optimum of about 36 C.


Biological activity and electronic structure of the aflatoxins. In theoretical studies of aromatic hydrocarbons, Pullman and Pullman (1969) used the molecular orbital method to correlate electronic structure with biological activity. They suggested that the interaction between carcinogens and their molecular receptors must occur through the K region of the carcinogenic molecule and involve a strong chemical binding of the type of an addition reaction. In the present work the electronic structures of aflatoxins B(1), G(1), 4-20 dehydro B(1) and of versicolorin A have been determined by the simple Hückel molecular orbital method using a computer, in order to see whether the correlation between electronic structure and biological activity is applicable to these compounds also. Calculations show that the 2-3 pi-bond, which has the highest bond order of the aflatoxin molecules, should be the most susceptible to electrophilic attack and is the most probable location of the K region. This is in agreement with the experimental observation of Dutton and Heathcote (1968) that aflatoxins B(1) and G(1) hydrate rapidly in dilute acid to the hydroxyaflatoxins B(2a) and G(2a) with an apparent total loss of carcinogenicity. The calculations also show that aflatoxins B(1) G(1) and M(1) have no suitable site for an L region and this probably accounts for their highly carcinogenic nature.


Biological activity of the methyl esters of prostaglandin E2 and its (15S)-15-methyl analogue.


Biological response of male and female volunteers to inorganic lead.


Biology of Hyostrongylus rubidus. VII. Some factors affecting populations of Hyostrongylus rubidus in the pig.


Biology of the rice rat (Oryzomys palustris natator) in a laboratory environment. 3. Morphology of dentition.


Biomphalaria glabrata: procedures for obtaining large numbers of embryos for cell cultures.


Biomphalaria glabrata: growth and differentiation of embryo fragments in extended culture.


Biosynthesis of camptothecin. I. Definition of the overall pathway assisted by carbon-13 nuclear magnetic resonance analysis.


Biosynthesis of lasalocid. I. Incorporation of 13C and 14C labelled substrates into lasalocid A.


Biosynthesis of retinal in bovine corpus luteum. Bovine corpus luteum tissue was sliced and incubated with beta-[15,15'-(3)H]carotene. The conversion of radioactive beta-carotene into radioactive retinal was substantiated utilizing column chromatography, thin-layer chromatography, high-speed liquid chromatography, and a derivative formation. Lowering of the incubation temperature to 20 degrees C or boiling the tissue eliminated the conversion of beta-carotene to retinal. In addition, other carotenoids and possible oxidation products of beta-carotene in the corpus luteum were investigated. Our results indicate that the bovine corpus luteum possesses the ability to synthesize retinal in situ, which may play a role in reproductive functions.


Biosynthesis of the verrucarins and roridins. 1. The transformation of mevalonic acid into verrucarinic acid. Evidence for a hydrogen 1,2-shift.


Biosynthesis of volatile oils in Salvia sclarea in the course of germination. I.


Biosynthetic studies on pepstatin. Biosynthesis of (3s, 4s)-4-amino-3-hydroxy-6-methylheptanoic acid moiety.


Biotransformation of isosorbide dinitrate in humans.


Black-white differences in serum creatine phosphokinase (CPK) activity.


Bleeding disorders in urology. A practical approach to diagnosis and treatment.


Bleeding time from incisions standardized by protruding skin fold method.


Bleeding problems in the newborn infant.


Blood characteristics of the Holstein calf relevant in cardiopulmonary studies.


Blood coagulation and platelet-function parameters before and during parenteral administration of medroxyprogesterone acetate as a contraceptive agent.


Bipolar forceps for electrocautery in tonsillectomy.


Blood flow in resting (contralateral) arm and leg during isometric contraction. 1. Blood flow in resting forearm and calf were measured plethysmographically in healthy young men during isometric contraction performed both as a handgrip and as a dorsiflexion of the foot. The isometric contraction was maintained for 2 min at one third maximal voluntary contraction for the handgrip and half maximal voluntary contraction for the dorsiflexion of the foot. In some experiments the possible influence on blood flow of inadvertent muscle activation in the resting limb was checked by recording the e.m.g.2. Both handgrip and dorsiflexion of the foot produced substantial increases in heart rate and mean arterial pressure, the pressure rise being almost linear with time throughout the contraction.3. Isometric contraction produced a rapid increase in forearm blood flow which reached a maximum on average two and a half times the resting value after 1 min and then declined slightly. Similar increases in forearm blood flow were produced by handgrip and dorsiflexion of the foot.4. Unlike in the resting forearm, the blood flow in the resting calf increased only slightly during the first minute of contraction and then decreased again to the resting level.5. The flow increase in the resting limbs could not be ascribed to inadvertent muscle activation as judged from the e.m.g. recordings.6. It is concluded that isometric muscle contraction produces a rapid increase in blood flow in the resting forearm, but only a very slight flow increase in the calf. Since the flow increased faster than the arterial pressure it must to a certain extent be induced by active neurogenic vasodilatation. Similarly, the relative flow decrease during the latter half of the contraction concomitantly with a progressively rising arterial pressure suggests that the neurogenic effect on the resistance vessels changes character, becoming more vasoconstrictive, and this might be related to increased effort in sustaining the contraction.


Blood compatibility of biomaterials: further evaluation of the Lindholm test.


Blood gas analysis-a brief for instrument operators.


Blood group Abantu population and family studies.


Blood glucose measurement with Dextrostix and new reflectance meter. A new instrument, Eyetone, has been produced for use with a Dextrostix reagent strip for estimating blood sugar levels. It differs from the Dextrostix Reflectance Meter in having only one meter scale, a two-point calibration, and a range of measurement limited to 10-400 mg/100 ml. Results with the manufacturers' original calibration were unsatisfactory, but when recalibrated the performance of the instrument gave a regression equation line close to the ideal. The three Eyetone instruments tested were comparable in their accuracy and functional stability. Packed cell volumes in the blood samples in the range of 30-50% had a negligible effect on the results. The Dextrostix-Eyetone method represents a quick and reliable alternative to conventional laboratory methods for blood sugar estimation. It is especially useful for patients outside hospital.


Blood levels of rifampicin in liver diseases.


Blood groups, serum proteins, haemoglobin and some serum and red cell enzymes among the Kaoras of 24-Parganas in West Bengal (India).


Blue nevus and melanosis of prostate.

Blue nevus and melanosis of prostate.


Body measurements of black-tailed jackrabbits of southeastern New Mexico with implications of Allen's rule.


Body responses and recovery after two and one-half hour hypothermic circulatory arrest.


Body temperature of three species of whales.


Boerhaave's syndrome. A case report.

Boerhaave's syndrome. A case report.


Bone imaging with 99Tcm polyphosphate: a comparison with 18F and skeletal radiography.


Bone marrow involvement in Hodgkin's disease: pathology and response to MOPP chemotherapy.


Bone mineral after partial gastrectomy. I.


Bovine babesiasis: its diagnosis and control.


Bovine ketosis. I. Occurrence and incidence in herds affected by ketosis in eastern Norway 1967-1968.


Bovine nasal granuloma in Victoria. 2. Histopathology of nasal, ocular and oral lesions.


Bovine ketosis. II. Therapy and biological factors of significance for recovery.


Bovine plasma alkaline phosphatase activity in relation to age, J substance and beta-lactoglobulin phenotypes.


Brain acetylcholine and cholinesterase: effect of phenothiazines and physostigmine interaction in rats.


Brain ganglioside preparation: phosphotungstic acid precipitation as an alternative to dialysis.


Brain levels and turnover rates of presumptive neurotransmitters as influenced by administration and withdrawal of ethanol in mice.


Brain ribosomes in intracranial hypertension.


Brain scanning in the diencephalic syndrome.


Breast surgery.

Breast surgery.


Breast feeding and weaning practices in an urban population.


Bradykininogen values in blood plasma collected from human intervillous space: relation between its content from maternal peripheric plasma and from plasma of umbilical vessels.


Breath analysis as a technique in clinical chemistry.


Brief-tone audiometry with normal, cochlear, and eighth nerve tumor patients.


Brief vs. long term psychotherapy: a treatment decision.


British surgery today: perspective of a James IV surgical traveler.


Bronchial and extrabronchial factors in chronic airflow obstruction.


Bronchiectasis: results of surgical and conservative management. A review of 393 cases.


Broncholithoptysis: Two case reports.

Broncholithoptysis: Two case reports.


Brucella melitensis endocarditis: successful treatment of an infected prosthetic mitral valve.


Buffer-facilitated proton transport. pH profile of bound enzymes.


Brugia pahangi infections in Mongolian jirds and dogs following the ocular inoculation of infective larvae.


Bullet identification by non-striated land and groove marks of abnormally undersized barrels.


Bunyaviruses and bunyaviridae.

Bunyaviruses and bunyaviridae.


Buoyant density and thermal denaturation profiles of schistosome DNA.


Burkitt's lymphoma involving the kidney: urographic findings before and after therapy in an American child.


Business office reorganizes to give more personalized service.


C-glycosyl nucleosides. IV. Syntheses of several 4-(beta-D-ribofuranosyl)pyrazoles.


Cadmium: inability to induce hypertension in the rat.


Cadmium inhibition of hepatic drug metabolism in the rat.


Calcaneo-fibular abutment following crush fracture of the calcaneus.


Calcifying epithelial odontogenic tumor. A survey of 23 cases and discussion of histomorphologic variations.


Calcinosis cutis and renal failure.

Calcinosis cutis and renal failure.


Calcitonin hypersensitivity in healing rickets: evidence that phosphorus is the prime target of calcitonin.


Calcium accumulation in liver and calcium mobilization in bone of lead-poisoned rats.


Calcium and aging in the rotifer Mytilina brevispina var redunca.


Calcium ion: a modulator of parotid adenylate cyclase activity.


Calcium reversal of nerve blockade by alcohols, anesthetics, tranquilizers, and barbiturates.


Calcium transport across avian uterus. II. Effects of inhibitors and nitrogen.


Calcium transport in isolated rat hepatocytes.


Calculated field intensities near a high power UHF broadcast installation.


Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration.


California sea lion myoglobin. Complete covalent structure of the polypeptide chain.


Camera radiocardiography based on the first transit principle.


Camera-kinematography: a nuclear medicine procedure for imaging heart kinetics.


Can money buy the apporpriate use of services? Some notes on the meaning of utilization data.


Cancer mortality for males and females and its relation to cigarette smoking.


Cancer of the alimentary tract in Costa Rica.


Cancer of the colon, rectum, and anus: a review of 2313 cases.


Cancer of the thyroid.

Cancer of the thyroid.


Cancer of the colon: a comparison of survival factors.


Cancer resistance. II. Cancer variations in families in a normal population.


Cancerous diseases. 1. Rehabilitation.

Cancerous diseases. 1. Rehabilitation.


Cancer of the upper alimentary tract and larynx in Poland and in Polish-born Americans. Mortality for cancers of the buccal cavity and pharynx, oesophagus and larynx in Poland in 1959-72 was analysed and compared with cancer incidence registered in the selected regions of Poland, with cancer mortality and incidence in other countries, and with mortality among Polish-born migrants to the U.S.A.The patterns of occurrence of these cancers in Poland appear to be similar to those of other European and American countries, except perhaps for the rather high and still increasing incidence of laryngeal cancer. Among male Polish migrants, however, mortality for these cancers was distinctly higher than either in Poland or among native Americans. This contrast, largest for oesophageal and laryngeal cancer, decreased between 1950 and 1959-61, but only for those aged below 65. Similarity of these shifts with those observed for lung cancer is stressed and explanations are looked for. Factors associated with the studied cancers and outlines for the further studies are discussed briefly.


Cannabinoids: neurochemical aspects after oral chronic administration to rats.


Carbohydrate metabolism in fathers of babies with congenital malformations.


Cannabis sativa L. (marijuana). V. Pharmacological evaluation of marijuana aqueous extract and volatile oil.


Cancer chemotherapy in man.

Cancer chemotherapy in man.


Carbon monoxide-stimulated respiration in methane-utilizing bacteria.


Carbon 13 nuclear magnetic resonance of pentapeptides of glycine containing central residues of methionine, proline, arginine, and lysine.


Carbon-13 Fourier transform nuclear magnetic resonance. 8. Role of steric and electric field effects in fatty acid spectra.


Carcinoembryonic antigen by radioimmunoassay in the detection of recurrence during long-term followup of female genital cancer.


Carcinoembryonic antigen in the diagnosis of prostate carcinoma.


Carcinoma and related lesion in dog stomach induced by oral administration of N-methyl-N'-nitro-n-nitrosoguanidine.


Carcinoma in situ of the cervix. A private hospital study.


Carcinoma of the gastric stump.

Carcinoma of the gastric stump.


Carcinoma of ileal bladder stoma.

Carcinoma of ileal bladder stoma.


Cardiac amyloidosis in the elderly: associated elevation of serum alkaline phosphatase.


Carcinoma of urinary tract. Clinical significance of urinary phosphokinase activity in diagnosis.


Cardiac complications. Results of penetrating chest wounds involving the heart.


Cardiac effects of isoproterenol during graded myocardial ischemia.


Cardiac findings in pectus excavatum in children: review and differential diagnosis.


Cardiac effects of nicotine in dogs.

Cardiac effects of nicotine in dogs.


Cardiodynamics of exercise in the patient with stenosis of one coronary artery.


Cardiopulmonary function of awake, sedated, and anesthetized beagle dogs.


Carcinoid tumors of the rectum: Experience with 38 cases.


Cardiovascular abnormalities following tricyclic antidepressant drug overdosage.


Cardiovascular effects of marihuana in man.


Cardiovascular reactivity in the dog after chemical sympathectomy with 6-hydroxydopamine.


Cardiovascular malformations and oesophageal atresia.


Cardiovascular status, depressive affect, and other factors in reaction time.


Career choice variability in a university-based Family Medicine Program.


Carotid body tumor: ultrastructural observations.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1974.


Carnitine acetyltransferase: the question of multiple forms.


Case report. Cor triatriatum in a 3-month-old infant. An operable form of pulmonary hypertension.


Cardiac wall motion analysis using videodensitometry: a time-modulated vector display for evaluation of cardiac performance.


Case report. Familial 4-22 translocation with partial trisomy for the short arm of chromosome 4 in two sibs.


Case report. Generalized familial bronchomalacia.


Case report. The cat-eye syndrome with unusual skeletal malformations.


Case report: influenza virus infection complicated by severe renal failure.


Case report: Fetal death in utero management with laminaria and prostaglandin F2A.


Case report: Lymphangioma of the lung.

Case report: Lymphangioma of the lung.


Case report: Spontaneous hypertonic uterine contractions.


Case studies of contrasting approaches to organizing for health: an introduction to a framework.


Caste differentiation in Myrmica rubra: the rôle of hormones.


Casualty criteria for wounds from firearms with special reference to shot penetration. II.


Catabolism and tissue levels of ascorbic acid following long-term massive doses in the guinea pig.


Catalase activity in the developing rabbit testis.


Catecholamine-containing neurons of the nucleus locus coeruleus in the cat.


Catecholamine-induced myocardial dammage associated with phaeochromocytomas and tetanus.


Cathepsin B2 measurement by sensitive fluorometric ammonia analysis.


Cation content and transport characteristics of the sickle-cell erythrocyte and their relationship with structural changes in the membrane.


Cations and the binding of polyadenylate to cellulose.


Cauliflower mosaic virus structural proteins.


Causes of death in 3151 diabetic autopsy cases.


Causes of variation of copper, iron, managanese, zinc and magnesium levels in bovine livers. 2. The dispersion of trace metals in bovine livers and the effects of formalinized storage on mineral concentrations and moisture content.


Caustic stricture of mouth and oesophagus.


Cell generation in the subependymal layer of the rat brain during the early postnatal period.


Cell types in cutaneous type I mechanoreceptors (Haarscheiben) and their alterations with injury.


Cell-mediated lympholysis: studies on the identification of the killer cell.


Cell-mediated immunity in the chicken: cytotoxicity induced by specific soluble antigens.


Cellular immunity in Hodgkin's disease: comparison of cutaneous reactivity and lymphoproliferative responses tp phytohemagglutinin.


Central effect of prostaglandin E1 (PGE1) on prolactin release.


Cellular and humoral responses of autosensitized rabbits to a testis cryo-injury.


Causes and prevention of blindness.

Causes and prevention of blindness.


Central implantation of cannabinoids: induction of epileptiform discharges.


Central nervous system affection in connection with "ordinary" measles.


Centrally acting skeletal-muscle relaxants.


Central release of acetylcholine following administration of morphine to unanesthetized rabbits.


Centre and surround influences on the proximal negative response of the pigeon retina. 1. Extracellular field potentials were recorded with micro-electrodes in the inner plexiform layer of the pigeon retina. Stimulus patterns were projected on a tangent screen.2. Maximal responses to a 1 degrees spot were produced from a receptive area 2-3 degrees in extent. Annuli centred over this area produced a different response wave form.3. The responses to centred spots and annuli presented synchronously do not superpose: they interact in a way suggesting transient mutual antagonism. The response to spot onset and offset can be suppressed either by annulus onset or by annulus offset.4. A steady annulus has little effect on the response to spot stimuli, but a steady centred spot enhances the response to annular stimulation.5. The results suggest that the PNR results from convergence of on-centre and off-centre pathways, which are embedded in a widespread suppressive surround.


Cephalometric analysis in diagnosis and treatment planning of craniofacial dysostoses.


Cephalothin, carbenicillin, and gentamicin combination therapy for febrile patients with acute non-lymphocytic leukemia.


Cerebellar stimulation in the rat: complex stimulation-bound oral behaviors and self-stimulation.


Cerebral blood flow, internal carotid artery pressure, and the EEG as a guide to the safety of carotid ligation. Twenty patients with aneurysms of the internal carotid artery underwent temporary clamping, in turn, of the internal and then the common carotid artery. Cerebral blood flow, internal carotid artery pressure, and the EEG were recorded to assess the probability of cerebral ischaemia after permanent ligation. With this method of monitoring the cerebral circulation, 17 of the 20 patients had a permanent carotid ligation without neurological deficit; in the other three ligation was contraindicated. Although a correlation was observed between the reduction of cerebral blood flow and the fall in internal carotid artery pressure caused by temporary clamping (P<0·01), the scatter of data was too wide to predict cerebral blood flow from the change in carotid artery pressure. Similarly, EEG slowing was usually associated with low cerebral blood flow but exceptions occurred. Ligation was safe when, during temporary clamping, cerebral blood flow exceeded 40 ml/100 g/min, but was deemed unsafe when flow was less than 20 ml/100 g/min. In the range 20-40 ml/100 g/min, consideration of the internal carotid artery pressure permitted more patients to be safely ligated than if the decision had rested on changes in cerebral blood flow alone.


Cerebral palsy and the low-birth-weight child.


Central pontine myelinolysis.

Central pontine myelinolysis.


Cerebral veins in the surgical exposure of the middle cerebral artery.


Cerebrospinal fluid lactic acid level and pH in meningitis. Aids in differential diagnosis.


Cerebrospinal fluid uric acid levels in cerebral atrophy occurring in psychiatric and neurologic patients.


Cervical intradural arachnoid cyst in a 3-year-old child. Report of a case.


Cervical lung hernia.

Cervical lung hernia.


Cervical pseudomeningocele after laminectomy as a cause of progressive myelopathy.


Chairman's introduction.

Chairman's introduction.


Change in health care services: For Indian Americans.


Changed physiology in wheat plants treated with the herbicide methabenzthiazuron.


Cerebral blood flow and brain stem lesions in comatose patients.


Changes in abdominal vascular capacity in response to stimulation of efferent sympathetic nerves.


Changes in body fluid distribution and interstitial tissue complicance during the development and reversal of experimental renal hypertension in the rat.


Cerebral lipids in cases of postcomatous encephalopathy.


Changes in carbohydrates during growth and development of cheena (Panicum milaceum Linn.).


Changes in bovine mammary gland permeability after intramammary exotoxin infusion.


Changes in clinical values of cattle infected with Clostridium chauvoei: preliminary report.


Changes in composition of mucin in the mucosa adjacent to carcinoma of the colon as compared with the normal: a biochemical investigation. Fifteen surgical specimens from patients with carcinoma of the colon and rectum were studied. Scrapings from normal mucosa distant from the tumour and from macroscopically normal mucosa adjacent to the tumour (;transitional') were used for chemical estimation of hexosamines, sialic acid, and proteins. The presence of hexosamines and sialic acid was confirmed in both normal and transitional mucosa. Transitional mucosa showed increased levels of total hexosamines and sialic acid as compared with the normal and this was accompanied by an increase in neuraminidase-sensitive sialic acids. The present data have been compared with previous histochemical and autoradiographic studies and it is suggested that the changes described in the transitional mucosa are transformations representing an early stage of carcinogenesis.


Changes in axon terminals of the claustrum following cortical lesions--electron microscopic investigations.


Changes in egg white during incubation of the fertile egg.


Changes in food intake and nitrogen metabolism of rats while adapting to a low or high protein diet.


Changes in habituation of the EEG to water deprivation and crop loading in Gallus domesticus.


Changes in hepatic RNA synthesis in the starve-refeed response of the rat.


Changes in megakaryocyte development following thrombocytopenia.


Changes in magnesium concentration of the vitreous humour of exenterated human eyeballs immersed in sea water.


Changes in myocardial norepinephrine in Indian domestic pigs after two-stage coronary ligation.


Changes in myosin cross-bridge attachment during oscillatory contractions of insect fibrillar muscle.


Changes in distribution of ribosomes during germination of rye (Secale cereale L.) embryos.


Changes in pulmonary vascular resistance due to platelet aggregation; vasoconstriction or vascular obstruction?


Changes in the enzymatic activity of the human endometrium during cycle and pregnancy.


Changes in sensitivity of the estradiol-LH feedback system with puberty in the female rat.


Changes of serum growth hormone in psychosomatic disorders.


Changes of enzyme pattern in the sympathetic nervous system of adult mice after submaxillary gland removal; response to exogenous nerve growth factor.


Changing medical complications of illicit drug use.


Characterisation of Mycoplasma pneumoniae growth factors in bovine serum fraction.


Characteristics of an alkaline phosphatase activity in brown recluse venom.


Characteristics of males indicted and convicted of homicide.


Characteristics of lymphocyte responses to phytomitogens: comparison of responses of lymphocytes from normal and lymphocytotic cows.


Characterization of an immune response gene in mice controlling IgE and IgM antibody responses to ragweed pollen extract and its 2,4-dinitrophenylated derivative.


Characteristics of rabbit globin mRNA purification by oligo(dT) cellulose chromatography.


Characterization of carbohydrate metabolism in the isolated fetal rat heart. Effects of fasting and alloxan diabetes.


Characterization of malignant thyroid gland tissue by magnetic resonance methods.


Characterization of silver sulfadiazine and related compounds.


Characterization of prostaglandins by combined gas-liquid chromatography and chemical ionization mass spectrometry.


Characterization of temperature-sensitive mutants of adenovirus type 5: synthesis of polypeptides in infected cells.


Charge injection and charge storage in lipid multilayers.


Characterization of the blastogenic response of C58 spleen cells: age-dependent changes.


Charing Cross Hospital.

Charing Cross Hospital.


Chemical and biological characterization of succinyl neocarzinostatin.


Chemical and clinical evaluation of the continuous-flow analyzer "SMAC".


Chemical and reflex drives to breathing during resistance loading in cats.


Chemical and physical properties of an arabinogalactan-peptide from wheat endosperm. 1. An arabinogalactan-peptide from wheat endosperm was studied by using physicochemical techniques and some aspects of its chemical structure were determined. 2. The arabinogalactan-peptide is a non-associating, polydisperse macromolecule ([unk]=22000) which exhibits only minor non-ideal effects in aqueous solution. 3. Examination of the products of partial acid hydrolysis of the polysaccharide component showed that arabinose is present in the alpha-l-arabinofuranosyl configuration, and i.r.-absorption spectroscopy and optical-rotation studies suggest that the d-galactopyranose residues are linked by glycosidic linkages in the beta-anomeric configuration. 4. The arabinogalactan is linked to a peptide which represents 8% (w/w) of the arabinogalactan-peptide and which may be present as a molecular core. Partial degradation of the polymer by successive treatment with oxalic acid and NaOH showed that the linkage between polysaccharide and peptide involves galactose and hydroxyproline residues and is glycosidic in nature. A tentative model is proposed for the structure of the wheat endosperm arabinogalactan-peptide. 5. The subcellular location and function of the arabinogalactan-peptide is discussed in relation to previous work with related molecules.


Chemical composition of the coxal fluid of the argasid tick Ornithodoros savignyi.


Chemical constituents of gentianaceae. IX. Natural occurrence of erythrocentaurin in Enicostemma hyssopifolium and Swertia lawii.