Gastric secretion in the chicken. General discussion.


Gastric inhibition by subcutaneous infusion of secretin in fistula chickens.


Falciparum malaria associated with jaundice, renal failure and anaemia.


In defence of the unwashed.

In defence of the unwashed.


Cellular and humoral antibody production against sheep erythrocytes in AKR mice. 2. Effect of the time interval on the secondary response.


The effects and side effects of diuretics in the prophylaxis of toxaemia of pregnancy.


Cellular and humoral antibody production against sheep erythrocytes in AKR mice. 3. Effect of passive antibody on the development of immunological memory.


Studies on the reactivation of bacteria photodamaged by an angular furocoumarin: angelicin.


Further thoughts on MSG.

Further thoughts on MSG.


An investigation of the tremorgenic actions of harmine in the rat.


Further chapters in the hydrazine story.


Mechanisms of chemical carcinogenesis.

Mechanisms of chemical carcinogenesis.


The hazards of aerosol propellants--real or not so real.


Influence of Ehrlich ascites carcinoma on repopulating ability of mouse bone marrow cells.


Skin-graft rejection during lymphomagenesis in urethan-treated mice.


Protection of mice against Gross leukemia by interfering action of nonleukemogenic C-type Murine viruses inoculated into newborns.


Evidence of the nonimmune regression of chemically induced papillomas in mouse skin.


Lymph flow and changes in intracellular enzymes during healing and rejection of rabbit skin grafts. 1. Autografts and homografts of full thickness skin were made on a hind limb of rabbits. During the following days the appearance and histological changes of the grafts were studied; the lymph flow from the limb, and the enzyme activities in the supernatant and cell pellet of the lymph after centrifugation were determined, as well as the enzyme activities in the graft roof and the underlying host tissue. It was further examined whether a lymphatic and vascular connexion occurred between graft and host tissue.2. During the first 5 days the grafts changed from pale blue to bright pink, became swollen, soft and had a mild cellular inflammatory exudate. Autografts then became pale, took on the appearance of normal skin with the inflammatory changes subsiding, whereas homografts became firm, showed heavy mononuclear cell infiltration, had a blotchy purple appearance due to thrombosis and haemorrhage, developed widespread necrosis and changed into a black hard scab which was eventually shed. With high dose homografts (6-8 grafts) these changes occurred 1-2 days earlier than with low dose (2-4) grafts.3. The flow of lymph increased during the first 5 days after grafting, then returned to normal with autografts but remained increased with homografts.4. In the supernatant of the lymph the activities of LDH and beta-glucuronidase did not change during the first 5 days but activities of cathepsin, acid phosphatase, GOT and GPT increased. With the autografts the increase in the activities of these four enzymes then subsided, but with the homografts they increased further and there was an increase in the activities of LDH and beta-glucuronidase, even greater than in those of the other four enzymes.5. In the cell pellets of the lymph the activities of the six enzymes did not increase during the first 5 days; with homografts, but not with autografts, they then increased. These increases occurred even though the cell count in the pellet remained unchanged. Thus some of the lymphocytes must have become ;activated' to contain higher enzyme activities.6. The enzyme activities in the roof tissue did not parallel those in lymph. They did not change during the first three days. During the following three days the activities of acid phosphatase, LDH, beta-glucuronidase and cathepsin increased, but not those of GOT and GPT which remained low. From then onwards the behaviour was different with auto- and homografts. With autografts only the activity of acid phosphatase continued to increase, those of LDH, beta-glucuronidase and cathepsin decreased and those of GOT and GPT remained low. With homografts the activities of LDH, beta-glucuronidase and cathepsin continued to increase and became even greater than in the supernatant of lymph, whereas the activities of acid phosphatase, GOT and GPT, remained low.7. In the bed tissue the activities of all six enzymes increased during the first 3 days after grafting, then the activities of GOT and GPT returned towards normal but those of the other four increased further. The only difference between auto- and homografts was that the increase in beta-glucuronidase and LDH activity was much greater with homografts.8. Lymph drainage became established with autografts on day 5 or 6 and then persisted. With homografts the dosage of grafts influenced the result. With low dosage (2-4 grafts) lymph drainage became established in a small percentage of the experiments, also on day 5 or 6, but it persisted for 2-3 days only. With high dosage, no lymph drainage became established. However, when the onset of rejection was delayed by treatment with cyclophosphamide lymph drainage became established also with high dosage homografts.9. Vascularization of the grafts was established on day 3 or 4, and persisted in autografts. In homografts a vascular shut down occurred at about the time of onset of rejection. It therefore occurred later with low than with high dosage and with high dosage on treatment with cyclophosphamide.10. It is concluded that the absence of lymph drainage from homografts is the cause of the small magnitude of increases in enzyme activities of lymph collected during and after their rejection. The increase results from ;activated' small lymphocytes which infiltrate the graft bed and junctional tissue and subsequently undergo necrosis, and that the establishment of a lymphatic connexion between the graft and host tissue is not a prerequisite for rejection.


Renal transplants in India.

Renal transplants in India.


Chloroquine resistance of Plasmodium falciparum in Brazil detected by a simple in vitro method. The sensitivity of Plasmodium falciparum to antimalarial drugs is primarily determined by observing changes in the level of parasitaemia after administration of drugs to man. Performance of such a study and interpretation of its results may present certain difficulties, especially when conducted among persons living in malarious areas. The present study was conducted to evaluate the usefulness of a simple in vitro method for detecting chloroquine-resistant strains among infected residents of Mato Grosso, Brazil. The findings indicated the participants were infected with chloroquine-resistant P. falciparum. Subsequent administration of a standard regimen of chloroquine (25 mg/kg) to these subjects confirmed the findings observed in vitro by failing to cure 28 out of 30 infections. This in vitro technique seems to provide a useful method of determining the presence or prevalence of chloroquine-resistant strains in a given area.


Life-long tolerance and chimerism in parental mice induced with F 1  hybrid cells.


Cultivation of the Douglas strain of Mycobacterium lepraemurium in continuous culture. Cultivation of Mycobacterium lepraemurium in cell-free media has not yet been successful, perhaps because of deterioration of the nutritional quality of the medium with prolonged incubation at 37 degrees C. Trials with a continuous culture technique, involving regular change of a simple liquid medium prepared from human placenta, demonstrated active fission of the Myco. lepraemurium cells. Abundant growth in the form by macroscopically visible colonies has not been achieved even after prolonged incubation up to 8 months.


Solubilization of lymphocyte and thymocyte antigens by a reversible chemical modification.


Stimulation of humoral antibody formation by polyanions. I. The effect of polyacrylic acid on the primary immune response in mice immunized with sheep red blood cells.


Stimulation of humoral antibody formation by polyanions. II. The influence of sulfate esters of polymers on the immune response in mice.


Activation of immunological memory cells in vitro.


Recognition of transplantation antigen in vitro: blocking of recognition structures by specific antibody.


Studies on antibody avidity at the cellular level. Effects of immunological paralysis and administered antibody.


Inhibition of macrophage spreading by supernatants of antigen-stimulated sensitized lymphocytes.


Anti-hapten response in vitro. Affinity differences in precursors of anti-hapten antibody-producing cells.


Cytophilic antibody and the regulation of the immune response.


Welfare and Medicaid coverage of the poor and near-poor in low-income areas.


Risk management and consumer participation in medical decision making.


Cholera El Tor at Kurnool.

Cholera El Tor at Kurnool.


Non-reproducibility of serial vectorcardiograms obtained by the Frank system.


A genetic mutation and gross pathologies in populations of the Triatoma protracta superspecies (Hemiptera: Reduviidae: Triatominae).


Setsuko Nakata (1930-1971).

Setsuko Nakata (1930-1971).


Retraction ring with therapeutic properties.


The functional impression with "Xantopren function".


Two newly described bacterial enteric pathogens: Vibrio parahaemolyticus and Yersinia enterocolitica.


Changes in blood volume in Falciparum malaria.


Serum vitamin B 12  level in patients with amoebic liver abscess, opisthorchiasis and infectious hepatitis.


Etiologic studies of old dog encephalitis. I. Demonstration of canine distemper viral antigen in the brain in two cases.


Membrane immunofluorescence on cultued indicator cells as a measure of virus production by mouse L cells and by two Moloney lymphoma sublines differing in immunosensitivity.


Studies on experimental toxoplasmosis.

Studies on experimental toxoplasmosis.


Variations in expression of surface antigens on cultured cells.


Immunofluorescence studies of the location of antibody production to insulin in guinea pigs.


Detection of tumor specific immune reactions in human melanoma.


Studies on nasopharyngeal carcinoma and Burkitt lymphoma by immunofluorescence.


Demonstration of antibodies against Mycoplasma pneumoniae in bronchial secretions by immunofluorescence.


Introductory review: characteristics of sera and conjugates.


Antinuclear-factor serum (homogeneous): an international collaborative study of the proposed research standard 66-233.


Immunofluorescence study of antigenic relationships between Brucella and some strains of Yersinia enterocolitica.


Studies on the standardization of antinuclear antibody (ANA) determination.


Introductory review: the optical system and quantitation of emission.


Toward quantitation of excitation.

Toward quantitation of excitation.


A study of filters and light sources in immunofluorescence microscopy.


A semiautomatic procedure for routine screening by immunofluorescence techniques.


Quantitation in immunofluorescence by radioimmunoassay.


Automation of an indirect fluorescent antibody test for syphilis.


An approach toward automation of antinuclear antibody (ANA) determination.


Studies on the reactions between fluorescent blood cells and antifluorescein antibodies in vivo and in vitro.


Characteristics of patient sera, conjugates, and antigens used in FTA-ABS tests.


Pathogeneis of experimental rabies as revealed by immunofluorescence.


Studies on the attraction of mosquitoes to insect-allergic patients after desensitization and to psoriatic patients.


Cell proliferation and antibody production in the secondary response in vitro towards a defined hapten.


Genetics of the immune response. 3. The restricted heterogeneity of antibodies to phage fd in a low responding inbred strain of mice.


Anaphylatoxin formation by contact activation of plasma. II. Implication of properdin and an unknown plasma factor in activation by zymosan.


Stimulation of humoral antibody formation by polyanions. 3. Restoration of the immune response to sheep red blood cells by polyanions in thymectomized and lethally irradiated mice protected with bone marrow cells.


Anaphylatoxin formation by contact activation of plasma. I. Activation by zymosan without participation of antibody.


The rex mutants of the domestic cat.

The rex mutants of the domestic cat.


Sex ratio in spina bifida and anencephaly.


Peritoneal dialysis: a review.

Peritoneal dialysis: a review.


Microbiologic determination of drug partitioning. I. Gelatin-acacia complex coacervate system.


Trachoma studies in Eritrea. I. Stability of the trachoma agent at low temperatures.


Trachoma studies in Eritrea. II. Comparison of laboratory results and clinical diagnosis.


Organ preservation: a comfortable experimental storage system for rat hearts.


Long-term hemodialysis in the elderly.

Long-term hemodialysis in the elderly.


Evaluation of a synthetic bioadherent dressing as a temporary skin substitute.


Dialysis of poisons and drugs--annual review.


Ultrastructural and functional effects of freezing rat hearts to -10 degrees C and -20 degrees C without a cryoprotectant.


The effect of rabbit anti-platelet anti-serum on the rejection of the pig and rabbit kidney by the dog.


Delay of xenograft rejection through oxidation of blood during hemodialysis.


Macrophage-cytophilic antibodies and the functions of macrophage-bound immunoglobulins.


Survey of numerical techniques for grouping.


Responses of the rat foetus to maternal injections of adrenaline and vasopressin. 1. Injection of 0.5-2.0 units of vasopressin or 25-100 mug of adrenaline into the peritoneal cavity of pregnant rats produced a transient slowing of the foetal heart. The bradycardia could be induced in foetuses after 15-21 days of gestation. Foetal heart rates dropped from normal values of 140-180 beats/min, often to less than 20 beats/minute. The period of bradycardia was dose dependent and ranged from 30 to 65 minutes.2. Maternal injection of the hormones produced a fall in foetal blood pressure from an average of 54, often to less than 20 mm of water, in 17-day foetuses. Direct injection of the hormones into the pericardial sac of the foetuses had the opposite effect and pressures rose an average of 15 mm of water 1 min after the injection.3. During the period of bradycardia, the potassium concentrations in foetal serum rose from an average value of 8.9 mequiv/1. to an average of 17.3 mequiv/litre. Concentrations of serum sodium fell from 126.2 to 121.4 mequiv/1. during the bradycardia. No changes were detected in the concentrations of either calcium or chloride. Foetal P(O2) levels fell from 25 to 15, P(CO2) rose from 61 to 89 or more, and pH fell from 7.19 to 6.86 during the bradycardia.4. Maternal death and uterine clamping caused foetal bradycardia and a rise in foetal serum potassium to an average of 20.2 mequiv/litre.5. It is concluded that interruption of normal uterine blood flow by vasoconstruction (adrenaline or vasopressin) or direct blockage (uterine clamping) results in a transient hypoxia, bradycardia, and serum ion changes in foetuses.


Protein polymorphism in man.

Protein polymorphism in man.


Distribution of octopamine in nervous tissues of Octopus vulgaris.


Human male meiosis: chromosome behaviour at pre-meiotic and meiotic stages of spermatogenesis.


An improved method for chromosome preparation from mouse liver.


Accumulation of neurophysin in the median eminence and the cerebellum of sheep with natural scrapie.


The gnotobiotic animal as a tool in the study of host microbial relationships.


Treatment of chronic mucocutaneous moniliasis by immunologic reconstitution.


Human antibodies to vascular endothelium.


Human precipitins against a micro-organism (Candida albicans) demonstrated by means of quantitative immunoelectrophoresis.


The effect of lung reactive antibodies on the pathogenesis of tuberculosis.


Inactivation of whole chromosomes in mammals and coccids: some comparisons.


Recombination and complementation between R factors in Escheichia coli K 12.


Characterization of the cellular immune defect in lepromatous leprosy: a specific lack of circulating Mycobacterium leprae-reactive lymphocytes.


A history of still photography in the operating room.


The structure of an intranuclear crystal as determined by sectioning, freeze-etching, and optical diffraction.


Origin and composition of the peritrophic membrane of the mosquito, Aedes aegypti.


The dogfish as a subject for neurophysiological research.


Stimulation of tubero-infundibular dopamine neurones and gonadotrophin secretion. 1. In ovariectomized rats pre-treated with oestrogen and progesterone, the intensity of the catecholamine fluorescence was determined by micro-fluorimetry in the cell bodies of the tubero-infundibular dopamine neurones (situated in the arcuate and periventricular hypothalamic nuclei). The concentrations of follicle-stimulating (FSH) and luteinizing hormone (LH) in serum and pituitary were estimated by bio-assay.2. The characteristic changes in fluorescence intensity of the tuberal catecholamine-containing nerve cell group that are induced by unilateral intermittent electrical stimulation of the arcuate nucleus or of the medial preoptic area during 5-60 min, were accompanied by a marked rise in serum LH concentration. With arcuate stimulation, the rise in serum LH paralleled the increase in the fluorescence intensity of the nerve cell bodies, whereas with preoptic stimulation, the initial increase in cellular fluorescence intensity preceded the rise in serum LH. Preoptic stimulation also caused a moderate fall in pituitary LH which was simultaneous with the increase in fluorescence intensity. No systematic changes in FSH concentration were observed during the time interval studied.3. Pre-treatment with the tyrosine hydroxylase inhibitor alpha-methyltyrosine completely blocked the increase in fluorescence intensity caused by electrical stimulation of the arcuate nucleus but did not prevent the rise in serum LH.4. It is concluded that the tubero-infundibular dopamine neurones serve as an intermediary between the medial preoptic area (and possibly other forebrain structures) and neurones containing releasing factors. Under the present experimental conditions, stimulation of the tuberoinfundibular dopamine neurones increased the release of LH, probably by promoting the release of LH-releasing factor.


Formation and function of kinins.

Formation and function of kinins.


Isotope renography combined with recording of isotope cystogram in patients with renal transplants.


The proteinpolysaccharides of cartilage.


Serum enzymes as indicators of hepatic disease.


Specificity of 4-aminoimidazole-5-carboxamide ribotide transformylase of Escherichia coli.


On-line computer applications in experimental medicine.


Rifampicin, a general review.

Rifampicin, a general review.


Computer-assisted patient monitor systems.


System for computer analysis of electrocardiograms.


Nursing stands taller because of Lillian D. Wald (1867-1940).


Formation of extracellular nuclear masses in organotypic cultures of rat retina.


Betram D. Lewin (1886-1971).

Betram D. Lewin (1886-1971).


Cell fusion in the study of tumor cells.


Chemical properties of basement membranes.


Feline leukemia.

Feline leukemia.


Human lymphocyte growth in vitro: morphologic, biochemical, and immunologic significance.


Formation of fusidic acid-G factor-GDP-ribosome complex and the relationship to the inhibition of GTP hydrolysis.


Effect of pepstatin on acid proteases.

Effect of pepstatin on acid proteases.


Transformations of antibiotics. I. Microbial transformation of antimycin A.


Mechanism of action of lividomycin A, a new aminoglycosidic antibiotic.


An improved simple method of specimen preparation for replicas or scanning electron microscopy.


An investigation of some organic chemicals as cathodoluminescent dyes using the scanning electron microscope.


Capillary-tube units for individual block preparation in light and electron microscopy.


Method for regional dynamic study of myocardial blood flow in man.


Method for the estimate of total coronary flow by  99 Tc tagged albumin microspheres.


Intrahepatic blood flow. Haemodynamic and functional behaviour after pig liver allograft.


1. Improvement criteria in drug trials with neurotic patients.


Measurement of cortisol secretion rate by isotope dilution techniques.


The use and development of in vitro thyroid function tests.


Determination of fibrinogen degradation products in serum and urine as a new diagnostic tool.


Serum and urinary fibrin-fibrinogen degradation products in renal disease.


Significance of fibrin split products in patients with renal failure.


Determination of fibrinogen derivatives by immunofluorescence in experimental and clinical kidney disorders.


Fibrinogen degradation products and renal disease.


Luis Federico Leloir. Nobel Prize in Chemistry 1970.


Centrifugal olfactory fibers in the cat. I. Site of termination. An experimental study with silver impregnation methods.


Side - chain cleavage of cholesterol by homogenates of isolated seminiferous tubules of rat testes.


Inhibition of growth of Clostridium pasteurianum by acetylene: implication for nitrogen fixation assay.


Cellular fatty acids of nonpathogenic Neisseria.


The chemotherapy of human and animal acute leukemia.


Polarity and enzyme functions in mutants of the first three genes of the tryptophan operon of Escherichia coli.


Hemoglobins A 2  and E levels in malaria.


Studies on the processing and properties of soymilk. II. Effect of processing conditions on the trypsin inhibitor activity and the digestibility in vitro of proteins in various soymilk preparations.


Spina bifida cystica. An orthopaedic criterion for the early closure of myelomeningocoeles. There is an urgent need for criteria upon which to base the decision to close a myelomeningocoele soon after birth. Orthopaedic experience advises that early closure of the spinal lesion should not be done unless there is active flexion power at both hips. This criterion is offered with the knowledge that there may occasionally be other exceptional factors to contradict it, but it is based on experience of 96 personal cases aged between 18 months and 7 years. These cases are analysed and discussed. A further possible criterion for not closing the spinal lesion early is the presence of a gross lumbosacral kyphosis.


The use of chondroitin sulfate in prolonging survival of adult skin allografts.


Myocardial infarction during pregnancy: report of two cases with a review of the literature.


Clinical judgment in the era of automation.


Effect of chemical modification of tyrosine residues on bone morphogenesis.


Escherichia coli alkaline phosphatase. An analysis of transient kinetics. 1. The hydrolysis of 2,4-dinitrophenyl phosphate by Escherichia coli alkaline phosphatase at pH5.5 was studied by the stopped-flow technique. The rate of production of 2,4-dinitrophenol was measured both in reactions with substrate in excess of enzyme and in single turnovers with excess of enzyme over substrate. It was found that the step that determined the rate of the transient phase of this reaction was an isomerization of the enzyme occurring before substrate binding. 2. No difference was observed between the reaction after mixing a pre-equilibrium mixture of alkaline phosphatase and inorganic phosphate, with 2,4-dinitrophenyl phosphate at pH5.5 in the stopped-flow apparatus, and the control reaction in which inorganic phosphate was pre-equilibrated with the substrate. Since dephosphorylation is the rate-limiting step of the complete turnover at pH5.5, this observation suggests that alkaline phosphatase can bind two different ligands simultaneously, one at each of the active sites on the dimeric enzyme, even though only one site is catalytically active at any given time. 3. Kinetic methods are outlined for the distinction between two pathways of substrate binding, which include an isomerization either of the free enzyme or of the enzyme-substrate complex.


Genetic aspects of carcinogenesis.

Genetic aspects of carcinogenesis.


Effect of cysteine on inducible synthesis of  -galactosidase in Escherichia coli.


On the interaction of carcinogens with DNA.


Some mathematical aspects of the medical diagnostic process. I. A general mathematical model.


Anti-DNA antibodies in rabbits hyperimmunized with somatic and common antigens in Enterobacteriaceae.


Gastric ulceration and haemorrhage as a potential cause of experimental failure following renal allografting in pigs.


A study of the methods available for the cytochemical localization of histamine by fluorescence induced with o-phthalaldehyde or acetaldehyde.


A trephine for skin transplantation.

A trephine for skin transplantation.


The Toshiba multiphasic health screening centre.


Actin in sperm tails and meiotic spindles.


Actin in the mitotic spindle.

Actin in the mitotic spindle.


Protein polymorphism.

Protein polymorphism.


Antibody and plant agglutinins stimulate phagocytosis of erythrocytes by Acanthamoeba.


Infectious pancreatic necrosis in rainbow trout in Scotland.


Paradox with after images.

Paradox with after images.


Syntactic class as a determinant of word-retrieval in normal and dyslexic subjects.


Evaluation of the thermodilution technique for measuring coronary sinus blood flow.


The neurologist--vintage 1971.

The neurologist--vintage 1971.


Richard Bright (1789-1858) and apoplexy.


Vascular deposits of immunoglobulin and complement in inflammatory myopathy.


Fluorescent cell tracing in multiple sclerosis brain tissue.


Double blind study using amantadine hydrochloride in the therapy of Parkinson's disease.


Obituaries. Walter F. Schaller. 1879-1970.


Richard B. Richter 1901-1970.

Richard B. Richter 1901-1970.


Hugo Mella, 1888-1969.

Hugo Mella, 1888-1969.


Howard D. Fabing, 1907-1970.

Howard D. Fabing, 1907-1970.


Charles Rupp, 1908-1970.

Charles Rupp, 1908-1970.


Arturo Rosenblueth, 1900-1970.

Arturo Rosenblueth, 1900-1970.


Sarah A. Luse, 1918-1970.

Sarah A. Luse, 1918-1970.


Frederick Lee Reichert, 1894-1969.

Frederick Lee Reichert, 1894-1969.


The control of essential tremor by propranolol.


Segmental myoclonus in meningomyelocele.


The American Neurological Association.

The American Neurological Association.


The suppression of malaria with dapolar: a trial of 4-monthly doses in a village community in the Gambia, West Africa.


C-reactive protein in Gambian Africans with special reference to P. falciparum malaria.


Pathogenesis of swine influenza infection produced experimentally in suckling piglets. 3. Multiplication of virus in the respiratory tract of suckling piglets in the presence of colostrum-derived specific antibody in their blood stream.


Tacitin and nobrium: new drugs for anxiety.


Oxypertine (integrin)--now promoted for the treatment of anxiety.


Hans Heinrich Landolt, (1917-1971).

Hans Heinrich Landolt, (1917-1971).


Phenotypic specificity of aneuploid states in Aspergillus nidulans.


Rates of spontaneous mitotic recombination in Saccharomyces cerevisiae.


R-factor elimination by thymine starvation.


Genetic analysis of spontaneous half-sectored colonies of Saccharomyces cerevisiae.


Triatoma dispar Lent, 1950 in Costa Rica (Hemiptera, Reduviidae).


Fixation effects on the relation between the tectorial membrane and the cilia of the hair cells.


The medially based chestflap for treatment of cancer of the hypophyarynx.


Reproductive isolation between Triatoma brasiliensis Neiva, 1911 and Triatoma petrochii Pinto & Barreto, 1925 (Hemiptera Reduviidae).


Idiopathic hypercalciuria. A state of compensated hyperparathyroidism?


Influence of BCG infection on growth of 3-methylcholanthrene-induced rat sarcomas.


Immunological aspects of bovine trypanosomiasis. IV. Patterns in the production of common antibodies.


The use of mice in research on contagious bovine pleuropneumonia.


The haematology and histopathology of Trypanosoma congolense infection in cattle. Ii. Haematology (including symptoms).


Serial suture holder for intracardiac valve replacement.


Occult endogenous infection within an arterial prosthesis.


Re-innervation of a free skin autograft.


6-Mercaptopurine (NSC-755) given intermittently in high doses: phase II study.


L-asparaginase (NSC-109229) plus azaserine (NSC-742) in acute lymphatic leukemia.


Single reversal trial of hydroxyurea (NSC-32065) in 91 patients with advanced cancer.


Immune response in chickens to infectious bronchitis virus, strain 33. II. Response to virus propagated in chicken embryo kidney cells.


Phase I study of a combination of azotomycin (NSC-56654) and 5-fluorouracil (NSC-19893) in malignant disease.


Treatment of metastatic Ewing's sarcoma with actinomycin D (NSC-3053).


Clinical efficacy and lack of toxicity of allopurinol (NSC-1390) given intravenously.


Remission induction in childhood leukemia with second course vincristine (NSC-67574) and prednisone (NSC-10023) therapy.


Initial clinical trials with 1,1-diphenyl-2-propynyl cyclohexanecarbamate (NCS-112682).


Immune response in chickens to infectious bronchitis virus, strain 33. I. Response to beta-propiolactone-inactivated virus.


Effect of some drugs on tumor dissemination and metastases.


Clinical and biochemical studies of high-dose intermittent therapy of solid tumors with hydroxyurea (NSC-32065).


Experimental botulism in gallinaceous birds.


Reactions of human sera to avian adenoviruses and Newcastle disease virus.


Mycoplasma meleagridis infection: development of air-sac lesions in turkey poults.


Treatment of carcinoma of the lung with 1-acetyl-2-picolinoylhydrazine (NSC-68626).


[Hemorrhagic encephalopathy induced by cyclophosphamide (NSC-26271) in suckling rats].


Clinical note. Phase II study of 1-aminocyclopentanecarboxylic acid (NSC-1026) in patients with cancer.


Comparison of   1 -testololactone (NSC-23759) and an estrogen-progestin combination (NSC-77622) in the treatment of metastatic breast cancer.


Therapy of acute leukemia with the combination of cytosine arabinoside (NSC-63878) and cyclophosphamide (NSC-26271).


Immunofluorescence of avian infectious bronchitis virus and Newcastle disease virus in singly and dually infected cell cultures.


Daunomycin (NSC-82151) in the treatment of metastatic neuroblastoma.


BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea; NSC-409962) in the treatment of malignant brain tumor--a preliminary report.


Vinblastine sulfate (NSC-49842) in the treatment of bronchogenic carcinoma.


Antitumor efficacy and toxicity of methyltrienolone (NSC-92858) in advanced breast cancer.


Monitoring: its meaning to treatment.

Monitoring: its meaning to treatment.


5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in patients with gastrointestinal carcinoma.


Postoperative pulmonary insufficiency: anoxia, the shunted lung and mechanical assistance.


Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880).


Pulmonary thromboembolism.

Pulmonary thromboembolism.


Mechanical cardiopulmonary substitution during open heart surgery.


Resectional therapy for complications of myocardial infarction.


Congenital malformations of the aortic arch associated with vascular rings.


Epilogue: the climate for research and practice.


Myocardial revascularization by direct and indirect methods.


Assisted circulation in the treatment of shock complicating acute myocardial infarction.


Cardiac pacemakers.

Cardiac pacemakers.


Tumors of the heart.

Tumors of the heart.


Cardiac trauma.

Cardiac trauma.


Cardiac transplantation.

Cardiac transplantation.


Anesthesia for operations upon the heart.


In memoriam. Moartin Amsler Rushton, 1903-1970.


Analysis of the changes in maxillary dental arch dimensions between Anglo-Saxon and modern times.


Physical properties of a nickel-chromium alloy for enamel veneering.


Investigations of the therapeutic success with dentures retained by precision attachments. I. Root-anchored complete overlay dentures.


The uterus and control of ovarian function.


Formation of a new phosphatidyl glycerol derivative in E. coli.


Methionyl-tRNAs and initiation of protein synthesis in vicia faba (L.).


Discovery of a new synthetic tetrapeptide having luteinizing releasing hormone (LRH) activity.


Reaction velocity response of the Escherichia coli biosynthetic L-threonine deaminase to rapid changes in substrate and modifier ligand concentrations.


Structure of the porcine LH- and FSH-releasing hormone. II. Confirmation of the proposed structure by conventional sequential analyses.


Studies on translocation of F-MET-tRNA and peptidyl-tRNA with antibiotics.


Membrane assembly in Escherichia coli. II. Segregation of preformed and newly formed membrane proteins into cells and minicells.


Membrane assembly in Escherichia coli. I. Segregation of preformed and newly formed membrane into daughter cells.


Introduction of an intramolecular crosslink at the active site of glyceraldehyde 3-phosphate dehydrogenase.


Ca 2+ -induced fusion of avian erythrocytes.


Photosensitization of pseudourea (NSC-56054).


Distribution and mechanism of clearance of L-asparaginase (NSC-109229).


Preliminary report from the Scandinavian adjuvant chemotherapy study group.


Autoimmune reactions in uveal melanoma.

Autoimmune reactions in uveal melanoma.


Clinical experiences with dibromodulcitol (NSC-104800) in solid tumors.


Clinical studies with a new podophyllotoxin derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidine- -D-glucopyranoside) (NSC-122819).


Short-term sequential therapy with vinblastine (NSC-49842) and cyclophosphamide (NSC-26271) in Hodgkin's disease.


Respiratory function in the aged.

Respiratory function in the aged.


Reticulum cell sarcoma, an oncologic model for a system of classifying the malignant lymphomas.


Fluorescence of 2-hydroxy-3-naphthoic acid hydrazide derivatives of side-chain carboxyl groups of proteins.


Cellular mechanisms of chromosome distribution.


Placental transfer of diazoxide and its hazardous effect on the newborn.


Immunosuppressive therapy in severe rheumatoid arthritis.


Axiom and process in genetics.

Axiom and process in genetics.


Resolution of a paradox with after images.


Double-blind evaluation of capuride in hospitalized patients suffering from loss of sleep.


A double-blind comparison of molindone and trifluoperazine in the treatment of acute schizophrenia.


Amino-acid contamination of aqueous hydrochloric acid.


Inhibition of methanogenesis by DDT.

Inhibition of methanogenesis by DDT.


Coital rates and the pill.

Coital rates and the pill.


A clinical trial of an antiserotonin compound, cinanserin, in chronic schizophrenia.


Patterns of hormone excretion in male and female homosexuals.


Electrical activity of oviducts in vivo.


Effects of cyclophosphamide on serum immunoglobulin levels in SJL/J mice.


Mitochondrial DNA of human-mouse cell hybrids.


Professor G. W. Harris.

Professor G. W. Harris.


Relationship of ochratoxin A to foetal death in laboratory and domestic animals.


Stereotaxic implantation for small animals: an "eyelet" technique.


E. coli transfer RNA: fractionation by electrophoresis on polyacrylamide gel.


Studies of human chorionic gonadotropin.


X-ray analysis and the structure of insulin.


Ultimobranchial follicles in the thyroid glands of rats and mice.


Biosynthesis of pregnenolone.

Biosynthesis of pregnenolone.


The pilot gland approach to the study of insulin secretory dynamics.


Metabolism and protein binding of sex steroids in target organs: an approach to the mechanism of hormone action.


Pulmonary blood volume and "pulmonary hematocrit" during hypervolemia in rats.


Substituted  , -dibromoacetophenones as antifungal and antibacterial agents.


An extra-corporeal shunt apparatus for blood detoxification.


Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase: gel-filtration behavior of apoenzyme and holoenzymes.


-cyanoamino acids and related nitriles as inhibitors of glutamate decarboxylase.


Trichomonal vaginitis treated with one dose of metronidazole.


Fritz Richard Schaudinn, 1871-1906: protozoologist of syphilis.


Sulfasymazine in pediatric practice.

Sulfasymazine in pediatric practice.


Experimental studies on the effects of glucagon on the denervated, transplanted heart.


Donald Winnicott. An appreciation.

Donald Winnicott. An appreciation.


A small computer system for EEG wavelength-amplitude profile analysis.


Harry L. Arnold, Sr., M.D., 1887-1971.

Harry L. Arnold, Sr., M.D., 1887-1971.


Quinazolines in man. Metabolism and preliminary evaluation of piquizil and hoquizil, two bronchodilators.


Isolation and identification of porcine Mycoplasma in Switzerland.


Texas Dental Association members alphabetical roster.


Report on the incidence of Clostridium botulinum in dressed poultry.


Studies on the immunity of the calf to colibacillosis. IV. The prevention of experimental colisepticaemia by the intravenous administration of a bovine serum IgM-rich fraction.


Epidemiological, clinical and serological studies on epidemic of mumps in an infant nursery.


The feeding of virginiamycin to growing rabbits.


Aminopeptidase B in human gingival exudate as affected by reduced oral hygiene and sugar diet.


Genetic complementation between Escherichia coli RNA polymerase mutants.


Visible gel electrophoresis and the determination of association constants.


Inhibition of RNase II by DNA.

Inhibition of RNase II by DNA.


Inhibition of colicin B by enterochelin.


Effect of arginine and canavanine on arginine messenger RNA synthesis.


The B protein of Escherichia coli tryptophan synthetase. II. New  -elimination and  -replacement reactions.


Properties of synthetic polydeoxyribonucleotide complexes containing adenine and bromouracil.


Rapid electrophoretic analysis for histone phosphorylation. A reinvestigation of phosphorylation of lysine-rich histone during rat liver regeneration.


Degradation of 5'-deoxyadenosylcobalamin by ribonucleoside triphosphate reductase and binding of degradation products to the active center.


Thiamine-binding protein and thiamine uptake by Escherichia coli.


Formation of ppGpp in a relaxed and stringent strain of Escherichia coli during diauxie lag.


Abortion in neural tube defect fraternities.


Malformations of the central nervous system in Glasgow. An examination of the evidence for clustering in space and time.


A comparison of diagnostic coding by manual and computerized methods.


The pinmen recall test as a measure of the individual.


Conservation of thermal indicator in lung circulation.


Human placental lactogen and human pituitary prolactin.


The metabolism of brown and white adipose tissue in the fetus and newborn.


Biochemical development of the lung: clinical aspects of surfactant development, RDS and the intrauterine assessment of lung maturity.


Pharmacology of the perinatal period.

Pharmacology of the perinatal period.


Respiratory distress in the newborn.

Respiratory distress in the newborn.


Metabolic rate and body size of the newborn.


Thermogenesis in the newborn infant.

Thermogenesis in the newborn infant.


The control of hyperbilirubinemia in the newborn.


The concept of the body schema: a critical review and some experimental results.


Social and medical aspects of illicit use of LSD.


Antivirus action of acrolein, glutaraldehyde and oxidized spermine.


Doctors at Greenwich.

Doctors at Greenwich.


Carl Alfred Moyer 1908-1970.

Carl Alfred Moyer 1908-1970.


The development of topical therapy.

The development of topical therapy.


Bacterial growth rates in crushed and devascularized skeletal muscle.


Bioassay of murine hemorrhagic shock. II. The relationship of sodium, osmolal, anionic, and water loads to survival.


A double blind controlled study on the antispasmodic effect and the side effect of Padrin composite injection.


Exercise for sedentary males.

Exercise for sedentary males.


Growth and nutrition in treated phenylketonic patients.


Monosodium glutamate: blood levels and absorption after oral and intravenous administration.


Oxidation of unsaturated fatty acids.

Oxidation of unsaturated fatty acids.


Metabolism of pyridoxine in the mouse.

Metabolism of pyridoxine in the mouse.


Medical education. Abraham Flexner--a reappraisal.


Overgrowth of a hypoplastic mandibular ramus after autoplastic bone grafting. An 18-year longitudinal radiographic study, using metallic implants.


Haemagglutinating ability of Corynebacterium pyogenes strains isolated from domestic animals.


In vivo evaluation of antibacterial chemotherapeutic substances.


The extracellular accumulation of metabolic products by hydrocarbon-degrading microorganisms.


Prevalence and distribution of antibiotic-producing actinomycetes.


Development of the fermentation industries in Great Britain.


Biochemical activities of Nocardia.

Biochemical activities of Nocardia.


Treatment of pseudo-arthrosis of the mandibular body by a sliding bonegraft.


Differentiation between mitochondrial and cytoplasmic protein synthesis in vivo by use of a temperature-sensitive mutant of Saccharomyces cerevisiae.


Carbamyl phosphate mediated inhibition of the sickling of erythrocytes in vitro.


Preferential binding of E. coli RNA polymerase to the AT-rich regions of bacteriophage f1 DNA.


The pepsin catalysed hydrolysis of bis-P-nitrophenyl sulfite.


Synthesis of the luteinizing releasing hormone of the hypothalamus and its hormonal activity.


Biogenesis of cocarboxylase in Escherichia coli: a novel enzyme catalyzing the formation of thiamine pyrophosphate from thiamine monophosphate.


Transfer of tyrosine into rabbit globin chain from two Escherichia coli tyrosyl-tRNA species.


Phage T7 lysozyme mRNA transcription and translation in vivo and in vitro.


The  -glucoside system of Escherichia coli. II. Kinetic evidence for a phosphoryl-enzyme II intermediate.


Biosynthesis of glucagon in isolated pigeon islets.


Chemical modifications of transfer RNA species. Metal ion binding to monoperphthalate-treated tRNA.


The amino acid sequence of ferredoxin from the sulfate reducing bacterium, Desulfovibrio gigas.


On the tryptophan residue in porcine LH and FSH-releasing hormone.


Stringent response of RNA synthesis in E. coli produced by a temperature shift-up.


The conformation difference between tRNA Met  f  and formylmethionyl-tRNA Met  f  from E. coli.


Inhibition of polyphenylalanine formation by tRNA prepared from Escherichia coli cells starved for amino acids.


Transfer RNA-primed oligoadenylate synthesis in maize seedlings. II. Primer, substrate and metal specificities and size of product.


Phagocidal effects of acrolein.

Phagocidal effects of acrolein.


The presence of 2-methylthio-N 6 -(  2 -isopentenyl)adenosine in leucine, tryptophan and cysteine tRNA's from Escherichia coli.


Deoxyribonuclease: a sensitive assay using radial diffusion in agarose containing methyl green-DNA complex.


Synthesis of bacteriophage T5 specific RNA in vitro.


Further studies on ribosome unfolding. The reversible release of 5-S RNA.


Isolation of yeast mitochondrial ribosomes highly active in protein synthesis.


Computer interpretation of acid-base data.


Old age, fever, and the lamp metaphor.

Old age, fever, and the lamp metaphor.


Galen on marasmus.

Galen on marasmus.


Susceptibility to polycythemia of hemopoietic spleen colonies produced by cultured embryonal liver cells.


Adherence column and buoyant density separation of bone marrow stem cells and more differentiated cells.


A painting in Gheel.

A painting in Gheel.


'Whether it is possible to prolong man's life through the use of medicine'.


The pharmacological table of ibn Biklãrish.


Schwann's way: cells and crystals.

Schwann's way: cells and crystals.


The good Samaritan: designed by Gerard de Jode; probably engraved by Hans Collaert.


Report of Jean-François Coste on his efforts to naturalize rhubarb.


A biblical description of motor aphasia and right hemiplegia.


Martin Levey, 1913-1970.

Martin Levey, 1913-1970.


A warm portrait of Paul Ehrlich.

A warm portrait of Paul Ehrlich.


Determination of glutamic and aspartic acids and their amides.


Methods for measurement of hydrogen isotope exchange in globular proteins.


Cancer research institute in Bratislava 1951-1971.


Fingertip injuries.

Fingertip injuries.


Management of fingertip injuries.

Management of fingertip injuries.


Immediate and definite reconstruction after hemimandibulectomy.


Some aspects of the purine metabolism of Trypanosoma cruzi in tissue culture.


Comparative crystallographic analysis of different bones with x-ray diffractometry.


A new approach to immunosuppression in human transplantation.


Effect of antibiotics on the ion-exchange of bacteria.


The biological significance of the insulinotropic effect of glucagon in man.


Periodontal and prosthetic conditions in patients treated with removable partial dentures and artificial crowns. A longitudinal two-year study.


A selected public health bibliography with annotations.


Purification and properties of yeast glycogen phosphorylase a and b.


Nature of the phosphodiester linkage of the phosphomannan from the yeast Kloeckera brevis.


Porous glass as a solid support for immobilisation or affinity chromatography of enzymes.


The nuclear envelope in freeze-etching.

The nuclear envelope in freeze-etching.


Psychotherapy and the dual research tradition.


The right to abortion: a psychiatric view.


The role of neutrophils in inflammation.


This long disease, my life-postscript to "He" (Percivall Pott and Alexander Pope).


Emotion as an accessory vital system.

Emotion as an accessory vital system.


The pupula duplex and other tokens of an "evil eye" in the light of ophthalmology.


Memories.

Memories.


Dr. Sylvester Emanuel Gould July, 31, 1900-Nov. 29, 1970.


Studies of the monoamine metabolism in the central nervous system in Jakob-Creutzfeldt disease.


A study in the morphology of the Finns and its relation to the settlement of Finland.


A bookshelf on community planning for health.


Peer ratings as predictors of school behaviour and delinquency.


Intrarenal blood flow distribution and autoregulation of renal blood flow and glomerular filtration rate.


A method for elution of immunoglobulin from the surface of living cells.


Double blind test with Baltix.

Double blind test with Baltix.


Use of Viregyt (amantadine hydrochloride) in the treatment of epidemic influenza.


David Gruby's influence on the development of medical science.


Some fundamental therapeutic problems of geriatrics.


[Pathohistological and histochemical studies of the pancreas in peritonitis].


Dye exclusion as a method of differentiating between living and dead lymphoid cells. In vivo and in vitro studies.


Intranuclear tubular bodies in islet cells.


A genetic approach to the study of the bacterial membrane.


Inhibition of R-factor transfer by levallorphan.


Isolation of a collagen from basement membranes containing three identical  - chains.


Synthesis of a proposed growth hormone releasing factor.


Recognition of early and late biosynthetic classes ribosomal proteins in Escherichia coli.


Precipitation of polyribosomes with pepsin digested antibodies.


Some properties of ribosomes from Myxobacter 495.


Specific interaction of tRNA 3'-terminal nucleotidyl transferase with polynucleates.


Prolonged fever with negative laboratory tests in an infant.


Localization of the basic aminopeptidases in Escherichia coli.


A clinical evaluation of antazoline in cardiac arrhythmia.


Quality control in bacteriology: preliminary trials. Six trials of quality control material sent in the form of artificial specimens are reported. A method of assessment using a computer for complex results, including antibiotic sensitivity tests, was employed. The trials were successful in showing the need for a comprehensive service and in bringing to light by this method a wide variety of errors.


Seasonal variation of streptococcal vulvo-vaginitis in an urban community. A study was made of patients investigated by general practitioners. Over a three-year period Streptococcus pyogenes (group A) was isolated most commonly from vaginal and vulval swabs collected in the winter. The serotypes of strains indicate that some had probably been derived from the skin and others from the respiratory tract. The two sources are thought to have masked a consistent, but not obvious, seasonal variation in streptococcal vulvo-vaginitis acquired usually from streptococcal infections of the respiratory tract in winter and from those of the skin in summer.


Light and electron microscopical studies of focal glomerular sclerosis. Renal biopsy material from seven cases of the nephrotic syndrome due to focal glomerular sclerosis has been studied by light, electron, and immunofluorescent microscopy. The nature of glomerular basement membrane changes and the scar tissue was also studied. It was found that the glomerular basement membrane and mesangial matrix formed the major components of scar tissue. On the basis of a short history in some of our cases, a poor response to steroid therapy in the early stages, and the distinct morphological changes, it is suggested that focal glomerular sclerosis has an independent origin and is not a stage of minimal change lesion.


Streptolysin S' formation of Streptococcus pyogenes grown on a new medium.


Hypoferremic reaction produced by endotoxin.


Initiation of the primary immune response to sheep red blood cells in the dissociated mouse spleen cell culture. II. Histochemical study on the cell clusters developed during the in vitro immune response.


The germination requirements of spores of Clostridium botulinum type E.


Transverse colostomy in the management of cancer of the colon.


The multiplication of Mycobacterium leprae in mouse foot-pads and the ambient temperatures.


Induction of virus-inhibiting factor or interferon by cell fractions of Mycobacterium tuberculosis.


Polyps of the rectum and colon.

Polyps of the rectum and colon.


Results of radiation therapy of malignant lymphomas, especially of reticulum cell sarcoma (1946-1963).


DNA, RNA and protein interactions.

DNA, RNA and protein interactions.


"Repetitive" DNA in higher organisms.

"Repetitive" DNA in higher organisms.


Informational macromolecules during the early development of sea urchins.


Nuclear magnetic resonance and the state of water in cells.


Short-lived free radicals in aqueous solutions of biomolecules.


Treatment of ameloblastoma of the mandible: resection via the intraoral route and simultaneous reconstruction by means of autogenous bone transplant.


John Harwood Rake, M.R.C.S. (Eng.), L.R.C.P. (Lond.).


Malaria and its prevention in military campaigns.


Studies on two high-affinity enolase inhibitors. Reaction with enolases.


Biogenic amines and psychiatry.

Biogenic amines and psychiatry.


Digital computer quantitation of electrocardiographic repolarization changes for studies of ischemic coronary heart disease.


Computer analysis of fibrinogen tracer data.


Iteration and interaction in computer data bank analysis: a case study in the physiologic classification and assessment of the critically ill.


Computer analysis of blood gases and of acid-base status.


The caries-pathogenetic theories of to-day.


Studies on skin allograft reaction in closed colony black hairy mice previously implanted with selected malignant tumors.


Application of x-ray diffraction to analytical problems of occupational health.


Fibrous glass-lined air transmission systems: an assessment of their environmental effects.


Two approaches to arrhythmia detection by digital computer in the coronary care unit.


Eosinophilic granuloma of bone. Review of literature and case presentation.


Electrotherapy in acute myocardial infarction.


Mechanical assistance to the circulation.


The classic. Control of bone growth by epiphyseal stapling. A preliminary report. Journal of Bone and Joint Surgery, July, 1949.


Immune response in tumor-bearing mice.

Immune response in tumor-bearing mice.


Establishment of a new human cell line derived from non-malignant endometrium.


Comments on aspects of the theory of psychic energy.


Peace Prize 1969: laudation.

Peace Prize 1969: laudation.


Visual perception: its development and maturation from birth to adulthood.


Mechanism of action of showdomycin. V. Reduced ability of showdomycin-resistant mutants of Escherichia coli K-12 to take up showdomycin and nucleosides.


Children's reactions to the death of a parent: a review of the psychoanalytic literature.


Anti-microbial effect of combinations of colistin methanesulfonate and chloramphenicol. II. In vivo effect.


Anti-microbial effect of combinations of colistin methanesulfonate and chloramphenicol. I. In vitro effect.


Adenylyldideoxykanamycin B, a product of the inactivation of dideoxykanamycin B by Escherichia coli carrying R factor.


The structure determination of an enzymatic inactivation product of 3',4'-dideoxykanamycin B.


History of medicine.

History of medicine.


Retrograde amnesia: time dependent effects of rhinencephalic lesions.


The effect of monocular deprivation on the synaptic contacts of the visual cortex.


Diagnostic criteria for overripeness ovopathy.


In memoriam William Henry Daines Trubshaw 1908-1971.


Alteration in the radiosensitivity of Escherichia coli 15T -  through the induction of unbalanced growth by cysteine.


N-acetylhexosamine-induced alteration in biological behavior of cultured mammalian cells.


Suppression of tumor growth and induction of specific tumor immunity by intradermal inoculation of a mixture of living tumor cells and live Mycobacterium bovis in syngeneic mice.


The application of radiocardiography in measuring pulmonary pressures and resistances.


Ribosomal proteins. XI. Isolation of proteins form 70S ribosomes of Escherichia coli.


The purification of thymidine kinase from Escherichia coli by affinity chromatography.


Cellular immune responses and prognosis in malignant lymphomas.


In search of a key.

In search of a key.


Relevance of in vitro tests for predicting responsiveness to antitumor agents.


Limited role of cell kinetics in clinical cancer chemotherapy.


Familial factors relating to prognosis of leukemia and lymphoma.


Kinetic behavior versus response to chemotherapy.


Radiochemical changes in the pyrimidine bases of nucleic acids.


Biological effects of laser radiation.

Biological effects of laser radiation.


Estradiol uptake by induced rat mammary tumors and its implications for the treatment of breast cancer.


Scintigraphy of the pericardial sac as a valuable diagnostic aid in hemorrhagic effusion.


Can we live without Vietnam?

Can we live without Vietnam?


The integrative aspect of ability.

The integrative aspect of ability.


Attendance, achievement and social class. The differential impact of non attendance upon school achievements in different social classes.


Functional capacity, alloxan sensitivity and vascular supply of pancreatic islet parenchyma during the first week after duct ligation. An experimental study in rats with microangiography.


Mass spectrometry in drug research.

Mass spectrometry in drug research.


Principles and practice of Hansch analysis: a guide to structure-activity correlation for the medicinal chemist.


Simple and rapid procedure for chromatographic identification of multiple transfer RNA species from Escherichia coli.


Preparation of  14 C-fluorescein isothiocyanate.


Properties of the hexose transport systems of Aspergillus nidulans.


Local and non-local interactions of fluxes mediated by the glucose and galactoside permeases of Escherichia coli.


Electron microscopic studies of the pancreatic islets and some other organs in experimental congenital diabetic rats.


Luteinization of ovaries under stressful conditions in persistent-estrous rats bearing hypothalamic lesions.


Unmasking additional bacilli in gram-negative rod bacteremia.


Portrait of a dean.

Portrait of a dean.


Erythropoietin and renin levels in human renal allotransplant patients.


SSA penny-wise, pound-foolish about home health service.


Rich Grand Rapids medical history began in 1835.


Early salvage in acute hand injuries with a primary island flap.


Experimental studies on island flaps. 1. The surviving length.


Total osteotomy of the middle third of the face for faciostenosis or for sequelae of Le Fort 3 fractures.


Bending an iliac bone graft for anterior mandibular arch repair.


Lack of correlation between coronary thrombosis and myocardial infarction or sudden "coronary" heart death.


The pluricausal cardiopathies.

The pluricausal cardiopathies.


Research with psychedelics. Some biopsychological concepts and possible clinical applications.


Treatment of histiocytic lymphoma in Uganda adults.


Bacteriologic examination of guinea pig milk.


Changes in cation concentration in spores of Bacillus licheniformis during germination induced by L-alanine.


Hyperketonemia-ketogenesis and ketone body metabolism.


Hypoglycemia in ketotic cows.

Hypoglycemia in ketotic cows.


Medicine in Maryland, 1634 to 1835.

Medicine in Maryland, 1634 to 1835.


Management and nutritional aspects of ketosis.


Learning processes in physician education: integrating psyche and soma.


Role of amniotic fluid (review).

Role of amniotic fluid (review).


Finding of the G cells of the human pancreatis islets.


Choice of optimum therapeutical strategy in the treatment of complicated tooth caries.


X-rays in Singapore. I. The first five years from 1896-1900.


Factors influencing the production of kanamycin by Streptomyces canus.


Protein malnutrition in children: advances in knowledge in the last ten years.


Carboxypeptidase A: a protein and an enzyme.


The structure of papain.

The structure of papain.


Survival of iliopsoas muscle after Sharrard procedure. An electromyographic study.


Homogeneous catalysis: applications and implications.


Mechanisms of palladium(II)-catalyzed reactions.


A reduced activity of a deoxyribonuclease requiring ATP in Escherichia coli infected by bacteriophage T4.


Properties of the internal invertase of yeast, Saccharomyces cerevisiae.


Bovine pepsinogen and pepsin. IV. A new method of purification of the pepsin.


Excitation and prolonged waking produced by catecholamines injected into the ventricular system of cats.


On the reaction of nucleic acids with isoniazid.


Organ culture of fetal-rat pancreas. 3. Ultrastructural changes occurring in B cells during stimulation of insulin release.


Intestinal hormones and insulin release: in vitro studies using rabbit pancreas.


The endocrine pancreas in anencephalics.


Investigations on the effects of epimestrol and stilboestrol upon the release of FSH and LH.


Effect of epinephrine upon  45 Ca uptake by isolated of Langerhans.


Primary malignant bone tumours.

Primary malignant bone tumours.


Acute streptococcal pericarditis: report of a case treated with pericardiectomy.


The illiterate computer.

The illiterate computer.


Membership directory, New York Academy of Sciences.


The effect on the accuracy of polysulphide impression material after treating preparations with various agents.


Partial denture. The rebasing of tissue borne saddles. Theory and practice.


An instrument for tracing surface contours of impressions, casts and dentures.


Liv. 52 studies in acute hepatitis.

Liv. 52 studies in acute hepatitis.


Disorders of the nervous system in diabetes.


Emotional and psychosocial aspects of diabetes mellitus.


Cutaneous manifestations of diabetes mellitus.


Gastrointestinal manifestations of diabetes mellitus.


Diabetes in association with other endocrine disorders.


A prospective view of the treatment of adult-onset diabetes with special reference to the University Group Diabetes Program and oral hypoglycemic agents.


What is diabetes? Definition, diagnosis, and course.


Pathophysiology of diabetes mellitus.

Pathophysiology of diabetes mellitus.


Inheritance in diabetes mellitus.

Inheritance in diabetes mellitus.


Dietary therapy and prophylaxis of vascular disease in diabetics.


Hypoglycemia in diabetes mellitus.

Hypoglycemia in diabetes mellitus.


Medical aspects of diabetes in pregnancy and the diabetogenic effects of oral contraceptives.


Diabetes mellitus in childhood and adolescence.


Treatment of diabetic retinopathy: pituitary ablation and retinal photocoagulation.


Peer review.

Peer review.


Congenital disorders of the urea cycle and ammonia detoxication.


Computer-aided medical instrumentation: a practical reality.


Membership directory, New York Academy of Sciences.


International symposium on the structures and functions of vitamin-dependent enzymes in honor of Professor Hugo Theorell. Introductory remarks.


Tribute to Professor Theorell.

Tribute to Professor Theorell.


International symposium on the structure and functions of vitamin-dependent enzymes in honor of Professor Hugo Theorell. Historical survey and introductory remarks.


Structure and catalytic role of the functional groups of aspartate aminotransferase.


The contribution of chemotherapy to the control of tuberculosis as a community disease.


Influences of pyridoxine derivatives on the biosynthesis and stability of pyridoxal phosphate enzymes.


Binding of pyridoxal phosphate to apoenzymes as studied by optical rotatory dispersion and circular dichroism.


The role of phosphopantetheine in the yeast fatty acid synthetase complex.


Tricarboxylic acid activator-induced changes at the active site of acetyl-CoA carboxylase.


Analogs of pyridoxal or pyridoxal phosphate: relation of structure to binding with apoenzymes and to catalytic activity.


Thiamine pyrophosphate-catalyzed enzymatic decarboxylation of  -oxo acids.


Insulin and the pancreas.

Insulin and the pancreas.


Mechanism and stereochemistry of transamination.


Model studies on flavin-dependent oxidoreduction.


Drug-induced thrombocytopenia.

Drug-induced thrombocytopenia.


Leukocyte response in acute malaria.

Leukocyte response in acute malaria.


Carcinoma of the testis in a renal transplant recipient.


Trial of oral neomycin during peritoneal dialysis.


A doctor's dilemma over an electrocardiographic lead 3 before the days of lead 3R. An interpretation of historic importance (Prime Minister Baldwin and Dr. William Evans).


Gastric secretion studies in hypoxic rats.


Gas production with Salmonella typhimurium infection.


The role of the parents in adolescent suicidal behavior.


Gastric secretion study on dogs continuously perfused with histamine.


Renal functional failure associated with cirrhosis: a review.


Bacteriological and clinical activity of the ampicillin-gentamicin and cephalothin-gentamicin combinations.


State of the DNA incorporated by Escherichia coli "permeable" cells.


A rat liver RNA-DNA-protein complex with template activity for protein synthesis.


Release of RNA from a T 7  DNA template.

Release of RNA from a T 7  DNA template.


Estradiol-mediated template activity of mouse and rat uterine chromatin: an unsolved problem.


Fractions of RNA and ribonucleoprotein from bacterial polysomes. II. Reactions with sulphur mustard.


Formation of self-complementary RNA on a single strand of DNA by RNA polymerase from Escherichia coli.


The specificity of penicillopepsin.

The specificity of penicillopepsin.


'The great army of suffering'.

'The great army of suffering'.


The history and superstitions of birth defects.


History of the Department of Pediatrics, Meharry Medical College.


Management of transient hyperphenylalaninemia and tyrosinemia in low birth weight Negro infants fed high protein diets.


A tribute to Edward Perry Crump, M.D.

A tribute to Edward Perry Crump, M.D.


Esterification of tissue cholesterol with fatty acids in the lungs of tuberculous mice.


Relation between Px phages and generalised transducing particles of phage P22.


Location of uvr502 mutation on the chromosome of Escherichia coli K-12.


Female-specific phages and F-minus strains of Escherichia coli K12.


Isolation of Salmonella typhimurium mutants affecting the plaque morphology of phage P22.


A minor Q-independent pathway for the expression of the late genes in bacteriophage lambda.


Escherichia coli mutants temperature-sensitive for DNA synthesis.


Kinetics of metabolic processes as studies with radioactive tracers.


Recent advances in scanning.

Recent advances in scanning.


Space radiation and other medical aspects of space travel.


Studies of pulmonary and cardiac function using short-lived isotopes oxygen-15, nitrogen-13 and carbon-11.


Histopathologic lesions in cutthroat trout (Salmo clarki) exposed chronically to the insecticide endrin. Pathologic conditions associated with exposure to endrin were found in the gill, liver, pancreas, brain and gonad of cutthroat trout. Edema, hemorrhage and possibly intracapillary congestion characterized gill damage after exposure to the highest level of endrin in bath. Hepatic lesions in young trout were of a type frequently described as preceding the development of hepatomas in nutritionally deficient fish. The increased incidence and severity of hepatic degenerative changes observed in fish exposed to high levels of endrin suggested nutritional deficiency enhanced by exposure to endrin. Marked hyperplasia of pancreatic islets and irregular, atypical oocytes were observed after exposure to high endrin levels.


Ion movements in cell injury. Effects of the cationic detergent cetyl pyridinium chloride on the ultrastructure and function of the toad bladder. The effects of a cationic detergent, cetyl pyridinium chloride (CPC), on toad bladder epithelium were studied by means of electrophysiologic and sodium-flux measurements, chemical analysis, time-lapse phase-contrast cinemicrography and electron microscopy. At 10(-5) M, CPC caused a rapid loss of net sodium transport as reflected by the short-circuit current (SCC) but except for striking prominence of the glycocalyx, this dose caused no ultrastructural changes for at least 18 hours. Only a moderate decrease in resistance and increase in passive sodium flux were noted. At 10(-4) M, CPC caused a transient 1 to 2-minute increase in the bladder's rate of oxygen consumption followed by a decrease, and a rapid decline in SCC, followed a few minute later by a decrease in resistance accompanied by a greatly increased passive leak to sodium. A sequence of ultrastructural changes typical of other forms of lethal cell injury progressed to extensive cellular disruption by 1 hour after treatment with 10(-4) M CPC. In addition, unusual surface membrane changes were observed, consisting of extensive formation of vesicles and myelin figures at the cell surface. A significant fraction of the bladder's cholesterol content appeared in the incubation medium after 10(-4) M CPC treatment. With 10(-3) M CPC, a similar pattern of cellular degeneration proceeded much more rapidly, and in addition, the cellular remains reorganized into complex lamellar arrays resembling phospholipid crystalloids. The results are interpreted as indicating that in addition to inhibiting net sodium transport, CPC lethally injures cells by interfering with the function of the surface membrane as a permeability barrier, and in addition, leads to a drastic structural reorganization of membrane constituents.


Ultrastructural alterations in canine lung allografts. Morphologic alterations in transplanted dog lungs undergoing acute rejection were studied with the electron microscope. Earliest changes were swelling of the type I alveolar cells and cytoplasmic vacuolization in the capillary endothelial cells. Later, there was progressive infiltration of macrophages which contained large osmiophilic inclusions. Type II alveolar cells increased in number and showed vacuolization, fraying and membrane disruption of their lamellar inclusions. A decrease in the relative number of type II cell inclusions and extensive endothelial damage were observed in preterminal biopsies. The significance of these cellular changes in relation to pulmonary rejection requires further investigation.


Bacteremia in the pathogenesis of retrograde E. coli pyelonephritis in the rat. Female rats deprived of water overnight, and then given 1.0 ml of E coli 0111:B4 via the urethra, developed pyelonephritis. A nearly absolute association was found between the occurrence of bacteremia after the transurethral infusion and the development of pyelonephritis. An identical lesion was produced by a combination of forniceal damage and intravenous injection of E coli. The kidney damaged by reflux was shown to be more susceptible to hematogenous pyelonephritis than the obstructed kidney and the distribution of the infection was due to localization of bacteria in the damaged fornix but not to the route of infection. The induction of retrograde E coli pyelonephritis in the rat required a tear in the pelvic epithelium creating pyelovenous communications, and the resultant bacteremia produced pyelonephritis. The incidence of ureteral reflux and the volume of inoculum that refluxed to the renal pelvis was shown radiologically to be a function of bladder distensibility, which is reduced by withholding water for a few hours. In this system, retrograde E coli pyelonephritis developed from a combination of two factors: (1) reflux-induced damage to the renal pelvis so that E coli are introduced into the kidney and (2) hematogenous infection of the damaged kidney.


A scanning electron microscope study of the human glomerulus. The three-dimensional fine structure of human glomeruli taken at autopsy and by biopsy was studied under the scanning electron microscope. The podocytes and their cytoplasmic processes in their elaborate ramification on the capillary wall were clearly demonstrated in the glomerulus of the autopsy specimens fixed by perfusion of glutaraldehyde as late as 3 hours after death, and in the glomerulus of the biopsy specimen fixed by immersion in the same fixative. The human podocytes were characterized by marked irregularity in the ramification pattern of their cytoplasmic processes, as compared with those of the rat and the rabbit. The interdigitation of the terminal processes was always noticed between those of different cells. The extended loss of the terminal processes was seen in the glomerulus of a case with severe proteinuria. The presence of intercellular spaces between the sheet-like cell peripheries of the podocytes supports the author's hypothesis in his studies on experimental nephrosis of rats that the disappearance of the terminal processes is not due to syncytial fusion of neighboring podocytes, but to retraction of swollen processes toward the central portion.


Clinical evaluation of the long-acting injectable neuroleptic, fluspirilene, in the treatment of schizophrenic and mentally retarded patients.


Unrelated HL-A identical cadaver kidney transplants.


A selected public health bibliography with annotations.


Encouraging group practice: with gun and net through the health establishment.


Preferential interaction of manganous ions with the guanine moiety in nucleosides, dinucleoside monophosphates, and deoxyribonucleic acid.


Biochemical analysis of the naturally repaired sections of bacteriophage T5 deoxyribonucleic acid. II. Conditions for nucleotide incorporation under nonpermissive conditions.


Protection of ribosomes from thiostrepton inactivation by the binding of G factor and guanosine diphosphate.


Movement of the ribosome along the messenger ribonucleic acid during protein synthesis.


Inhibition of protein synthesis by 5'-sulfamoyladenosine.


A new fluorescent probe for protein and nucleoprotein conformation. Binding of 7-(p-methoxybenzylamino)-4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes.


A membrane-bound phospholipase A1 purified from Escherichia coli.


Production of mitochondrial peptide-chain elongation factors in yeast deficient in mitochondrial deoxyribonucleic acid.


Spectral properties of the chromophoric material associated with the deoxyribonucleic acid photoreactivating enzyme isolated from baker's yeast.


Singlet oxygen and biological systems.

Singlet oxygen and biological systems.


Unusual manifestation of malignant reticulosis of the skin: cutaneous lesion simulating parapsoriasis guttata.


Genetic analysis of sul mutants of Escherichia coli B.


A three-stage clinical evaluation of etonam (R 10 100) in the treatment of chronic athlete's foot.


A semi-automatic technique for conducting many bacterial matings concurrently.


I-like resistance factors with the fi+ character.


The safe tracer dose in medical investigation.


Potential early diagnosis of cancer with radioactive compounds.


The cyclotron: source of short-lived radionuclides and positron emitters for medicine.


Trace elements in biology and medicine.

Trace elements in biology and medicine.


Clinical studies of the use of bacteriophage in the treatment of cholera. This study reports the use of bacteriophage prepared in the USSR in the treatment of cholera. Patients with acute cholera were rehydrated with a standard intravenous solution and were then given a bacteriophage preparation in addition to maintenance intravenous therapy. The titre of the phage preparations was between 10(8) and 10(9) pfu/ml. Bacteriophage was given by mouth (25 ml for adults and 20 ml for children) for 3 days; in addition, some patients were also given an intramuscular injection (20 ml) of phage on the first day in hospital. For comparison, other groups of patients were given a standard tetracycline regimen or a placebo preparation. Daily vibrio and phage counts were made on stool samples from all patients and the vibrio strains isolated from each patient were tested for sensitivity to the phage preparation.The criteria used to evaluate the various therapies were duration of diarrhoea, volume of stool, and duration of vibrio excretion.The results of the study demonstrate that, in the doses used, the therapeutic effect of bacteriophage, if any, was markedly inferior to that of tetracycline and that in the current state of our knowledge bacteriophage, as used in this study, has no place in the treatment of cholera.


Tertiary relief of the skin surface, its development and significance.


A karyometric study of the experimentally synchronised rhythm of the glandula orbitalis externa in the albino rat.


Principle of growth in thickness of the heart ventricular wall in the chick embryo.


[Surgery and hypertensive patients].

[Surgery and hypertensive patients].


Flat whole-mount preparations of the lens capsule in fibrillopathia epitheliocapsularis, the so-called senile exfoliation or pseudoexfoliation.


The effect of oestrogenic treatment on the acid mucopolysaccharide pattern in skin of mice.


Serologic analysis of the lac + hybrid of Escherichia coli K-12 HFRC and variant Y of Shigella flexneri.


Humoral cross immunity in patients with malignant tumors.


Repeated immunization of rabbits with sheep red blood cells. I. Influence of the time of administration of the second dose of antigen on development of PFC-direct and PFC-indirect.


Significance of inter-dose variation in clinical evaluations.


Management of breast cancer.

Management of breast cancer.


Surgical correction of recurrent bony ankylosis of the temporomandibular joint.


One-stage mandibular-maxillary reconstruction in the treatment of gross disproportion of the jaws.


The management of the patient with severe multiple injuries. Immediate resuscitation.


Mandibular reconstruction in Nigeria.

Mandibular reconstruction in Nigeria.


Effects of glycine on spinal neurones grown in tissue culture.


Studies on liver regeneration. I.  131 Iododeoxyuridine as a precursor of DNA in normal and regenerating rat liver.


Human lymphocyte proliferation: DNA synthesis time.


Studies on liver regeneration. II. Effects of phenobarbital on the onset and pattern of rat liver regeneration following partial hepatectomy.


Technique of canine pancreatic allotransplantation.


Major General S.S. Sokhey (1887-1971).

Major General S.S. Sokhey (1887-1971).


Organ transplantation.

Organ transplantation.


Influence of cartilage extracts on the osteoblastic response in calvarial defects in rats.


Bacterial counts of Mycobacterium leprae on media enriched by substances of mycobacterial origin.


Letter to the editor. Gastric achlorhydria and cholera.


Some observations at the exit pupil of the microscope objective.


He. (Alexander Pope).

He. (Alexander Pope).


The separation of individual- and system-influences on behavior in social contexts.


The pathogenesis of diabetes mellitus in man.


The management of intracranial hypertension and brain edema during and after general anesthesia.


Lysogenic conversion in the Shigella flexneri group.


Roentgenologic methods in examination of the larynx. Model, phantom and clinical investigations.


S-amino acid metabolism and its regulation in Escherichia coli and Salmonella typhimurium.


Mutagenic and lethal effects of visible and near-ultraviolet light on bacterial cells.


Genetics of P2 and related phages.

Genetics of P2 and related phages.


Classification and mapping of spontaneous and induced mutations in the histidine operon of Salmonella.


Milislav Demerec (1895-1966).

Milislav Demerec (1895-1966).


The genetic effects of ionizing radiations.


Genetic factors in aging.

Genetic factors in aging.


Toward a general theory of genetic recombination in DNA.


Bibliography. Publications of M. Demerec.


Genetics of the Enterobacteriaceae. A. Genetic homology in the Enterobacteriaceae.


Genetics of the Enterobacteriaceae. B. Homology in the Enterobacteriaceae based on intercrosses between spaces.


Genetics of the Enterobacteriaceae. C. Molecular relationships among members of the Enterobacteriaceae.


A method for duplicating dentures. Some clinical applications.


Haematinics. I. Patho-physiological and clinical aspects.


Drug metabolism and interaction with particular reference to the liver.


Hypnotic phenomena: the struggle for scientific acceptance.


Infection and disseminated intravascular coagulation.


Inga Lohne Brauner.

Inga Lohne Brauner.


Serum and cerebral spinal fluid complement and serum autoantibodies in systemic lupus erythematosus.


Mary McMillan.

Mary McMillan.


Dorothea M. Beck.

Dorothea M. Beck.


Gertrude Beard.

Gertrude Beard.


Hazel E. Furscott.

Hazel E. Furscott.


Edith Monro.

Edith Monro.


Margaret Campbell Winters.

Margaret Campbell Winters.


Sarah Colby.

Sarah Colby.


Constance K. Greene.

Constance K. Greene.


Helen L. Kaiser.

Helen L. Kaiser.


Effects of spinal anesthesia on pregnant human uterine contractility. I. Effects during pregnancy.


Catherine Worthingham.

Catherine Worthingham.


Jessie L. Stevenson West.

Jessie L. Stevenson West.


Susan G. Roen.

Susan G. Roen.


Lois Ransom.

Lois Ransom.


Marguerite Irvine.

Marguerite Irvine.


Mary Clyde Singleton.

Mary Clyde Singleton.


Harriet S. Lee.

Harriet S. Lee.


Mary E. Nesbitt St. Coeur.

Mary E. Nesbitt St. Coeur.


Eleanor Jane Carlin.

Eleanor Jane Carlin.


Agnes P. Snyder.

Agnes P. Snyder.


Mary Elizabeth Kolb.

Mary Elizabeth Kolb.


Eugene Michels.

Eugene Michels.


A method of evaluation of the influence of aspirin formulations on gastrointestinal microbleeding in humans.


Arne Bertelsen in memoriam.

Arne Bertelsen in memoriam.


Bone growth in the femoral head following pedicled bone grafting. An experimental study.


The surgical treatment of traumatic lesions of the auditory ossicles.


Anesthesia in otological operations.

Anesthesia in otological operations.


Achievements in tropical medicine during the past twenty-five years.


A controlled evaluation of bromhexine and orciprenaline in the treatment of chronic bronchitis.


Double-blind comparative trial of doxepin and chlordiazepoxide in general practice.


A comparative trial of lorazepam and diazepam.


Evaluation of a new tranquillizer--WY 4036--in the treatment of anxiety.


Controlled trial of the treatment of 36 stutterers.


Recent perspectives in schizophrenia.

Recent perspectives in schizophrenia.


The psychological effects of propranolol in the abstinence phase of chronic alcoholics.


Megavitamin B-3 therapy for schizophrenia.


Atypical psychoses. A search for certainty in this ambiguous borderland.


A comparison of chlorprothixene and haloperidol in acute schizophrenia.


Correlation of fatty acid composition with thermal resistance of E. coli.


Uptake of amino acids by actidione-treated yeast cells. I. Specificity of carriers.


Effect of glucose starvation on the melting points of DNA following UV irradiation of Escherichia coli 15 T-U-his.


Possibility of use of colicin-refractory mutants in the study of localization of colicin receptors.


Uptake of amino acids by actidione-treated yeast cells. II. Effect of incubation conditions and metabolic inhibitors.


Uptake of amino acids by actidione-treated yeast cells. 3. Effect of sodium and potassium ions.


Recent experience with bacillemia due to gram-negative organisms.


Tetracyclines in the treatment of chronic trachoma in American Indians.


Virulence and in-vitro characteristics of four mutants of Newcastle disease virus.


Serologic studies of meningococcal infection and polysaccharide vaccination.


Intensified reactions to measles vaccine in unexposed populations of american Indians.


The effect of water diuresis on spread of bacteria through the urinary tract.


Computerized monitoring of cardiac output by thermal dilution.


R factors in strains of Shigella dysenteriae type 1 isolated in the western hemisphere during 1969-1970.


Medicine, stamps, and the history of man.


Clinical use of R-R interval prediction for ECG monitoring: time series analysis by autoregressive models.


Carbon monoxide: its relationship to air pollution and cigarette smoking.


The Society of Medical Officers of Health. Past, present and future.


Government standards activities.

Government standards activities.


Genetic analysis of "somatic" cells in filamentous fungi.


Hybridization between different genera in the Enterobacteriaceae.


Interrelations between vitamin E and polyunsaturated fatty acids.


Beethoven. Muss es sein? Es muss sein.

Beethoven. Muss es sein? Es muss sein.


Meningococcal infections. 5. Duration of polysaccharide-vaccine-induced antibody. Serum antibodies induced in 12 volunteer subjects by injection of group A and group C meningococcal polysaccharide vaccines were found to persist for periods exceeding 14 months. Antibody response was measured by indirect haemagglutination and fluorescent antibody assays. Peak titres were reached in 2-8 weeks.


The indirect fluorescent antibody test for the detection of occult malaria in blood donors.


Triton WR 1339 (TWR), an inhibitor of cancer dissemination and metastases.


Quantitative anatomical measurements on single isolated fibres from the cat spinal cord.


Role of iron in host-parasite interactions.


The differentiation of transplanted haematopoietic cells derived from bone marrow, spleen and fetal liver.


A filterable agent in throat washings of patients with infectious mononucleosis.


Gram-negative bacillary pneumonia.

Gram-negative bacillary pneumonia.


The origin, properties and fate of epithelioid cells.


Symptomatic volunteers in psychiatric research.


A study of 1-adamantamine hydrochloride during the 1970 Hong Kong influenza epidemic.


Dip-slide urine cultures in general practice.


Control of mosquitoes breeding in ricefields.


Inhibition of protein synthesis in Escherichia coli and L5178Y mouse leukemic cells by phenylalanine and tryptophan.


Throat swabs and swabbing technique.

Throat swabs and swabbing technique.


Julius Dreschfeld & late 19th century medicine in Manchester.


General practitioners' forum. Imipramine in the treatment of childhood enuresis.


Sulphadimidine and nalidixic acid therapy in urinary-tract infections in general practice.


Evaluation of psychotropic drugs in general practice. President's valedictory address.


A comparison of 'bisolvomycin' and oxytetracycline in the treatment of acute infective sinusitis.


The life and health of Joan of Arc. An exercise in pathography.


Antifertility agents.

Antifertility agents.


The prostaglandins.

The prostaglandins.


[Diagnostic possibilities of double-contrast arthrography in disorders of the knee].


Axonal transport: communication between soma and synapse.


A specific gas chromatographic method for assaying tissue acetylcholine: present status.


Mitochondria and protein synthesis in brain.


The effects of CNS active drugs on the metabolism of steroids in man.


Application of immunology to neurochemistry.


On mechanisms of norepinephrine release by amphetamine and tyramine and tolerance to their effects.


Serotonin neurons: localization and possible physiological role.


Storage and secretion of adrenal catecholamines.


Protein turnover and synthesis: relation to synaptic function.


Turnover rate measurements of brain serotonin in unanesthetized rats.


Hydrolysis of acyl phosphates by alkaline phosphatases.


The effect of guanylyl-5'-methylene diphosphonate on binding of aminoacyl-transfer ribonucleic acid to ribosomes.


Effect of edeine on aminoacyl-tRNA binding to ribosomes.


The museum of the college of radiologists of Australasia--a beginning.


Orvid. A new system for on-line application of a computer in the radiodiagnostic department.


Triethyltin--a useful research tool.

Triethyltin--a useful research tool.


Pyrrolizidine alkaloids and metabolic pyrroles.


A world view of cancer.

A world view of cancer.


Parent-child separation: psychological effects on the children.


Isoenzymes of lactic dehydrogenase and esterases in regenerating bone.


The influence of acrylic cement.

The influence of acrylic cement.


An experimental study of the immediate load bearing capacity of some commonly used iliac bone grafts.


The effect of diffusible acids on potassium ion uptake by yeast. 1. When yeast oxidizes ethanol at different pH values the uptake of K(+) corresponds closely to the amount of acetate accumulated at each pH value. 2. The addition of semicarbazide to the suspension buffered at pH4.75 inhibited both the K(+) uptake and the acetate accumulation by about 50%. 3. The addition of either acetate or propionate to the suspensions markedly increased the K(+) uptake. 4. The addition of acetate to the suspensions lowered the intracellular pH of the yeast from a resting value of pH5.80 to 5.56. 5. The ratio of the initial rate of K(+) uptake to O(2) consumption was 0.77. This ratio was increased to 1.77 in the presence of 10mmol of propionate/l.


Occurrence of long-chain fatty acids and glycolipids in the cell envelope fractions of baker's yeast. 1. The total yield of fatty acids from the whole envelopes was markedly higher than that obtained from the ordinary cell walls. In both samples the major fatty acids were C(16) and C(18) acids. 2. The whole envelopes contained C(18) acids and long-chain (C(19)-C(26)) fatty acids, in a higher proportion than did the ordinary cell walls. Fifteen fatty acids with more than 18 carbon atoms were identified, among which 2-hydroxy-C(26:0) and C(26:0) acids predominated. 3. A complex sphingolipid containing inositol, phosphorus and mannose was isolated from the whole cell envelopes. The main fatty acids of this lipid were 2-hydroxy-C(26:0) and C(26:0) acids. It was concluded that this sphingolipid is present both in the ordinary cell wall and in the plasma membrane of baker's yeast. 4. The neutral lipids amounted to over 50% and the glycerophosphatides to about 30% of the total fatty acid content of the whole envelope. The major fatty acids in these lipids were C(16:1), C(18:1) and C(16:0) acids. The proportion of fatty acids with more than 18 carbon atoms was lowest in the neutral lipids, whereas the neutral glycolipids contained the highest percentage of these fatty acids. Acidic glycolipids amounted to 14% of the total fatty acid content of the whole envelope. The presence of a cerebroside sulphate in this lipid fraction was demonstrated, whereas the high content of 2-hydroxy-C(26:0) acid found is caused by the complex inositol- and mannose-containing sphingolipid.


Heat induced changes in cells.

Heat induced changes in cells.


Factors inducing excystation in free-living amoebae.


Homocysteine synthesis in yeast. Partial purification and properties of O-acetylhomoserine sulfhydrylase.


Formation of acto-H-meromyosin and acto-subfragment-1 complexes and their dissociation by adenosine triphosphate.


Mechanism of mercuric chloride resistance in microorganisms. I. Vaporization of a mercury compound from mercuric chloride by multiple drug resistant strains of Escherichia coli.


Circular DNA molecules in Escherichia coli possessing the surface-antigen K88.


Properties of isoleucine hydroxamate-resistant mutants of Serratia marcescens.


Regeneration of Aspergillus nidulans protoplasts.


Subtraction radiology by electro-optical means.


A new Salmonella typhimurium DNA host specificity.


First phase in objective evaluation of new diagnostic tests. Application to thyroid uptake of  131 I.


The influence of dissolved oxygen on Pseudomonas AM1 grown on methanol in continuous culture.


Absence of polar effect of frameshift mutations in the E gene of the Escherichia coli argECBH cluster.


The Emperor of Russia and the Royal Humane Society.


High-frequency gene transfer in Pasteurella pseudotuberculosis.


Stereochemical problems in macrolide antibiotics.


Biosynthesis of polypeptide antibiotics.


C-nucleosides: aspects of chemistry and mode of action.


Microbial transformations of antibiotics.


Transfusion-induced malaria after open heart surgery.


The resistance of bacteria to antibacterial drugs: a selective review.