Identification of Mycoplasmatales: characterization procedures. A large collection of avian Mycoplasma cultures was used in studies to improve and develop biological and biochemical characterization techniques. Differential patterns among 11 avian serotypes were shown by carbohydrate fermentation, tetrazolium- and methylene blue-reduction reactions, breakdown of arginine, and the formation of film on egg yolk-agar. Some cultures fermented as many as 14 carbohydrates. Polyhydric alcohols and pentoses were among the compounds fermented. An improved procedure for determining methylene blue reduction by Mycoplasma was developed. These simple, rapid procedures are reproducible and should be useful in grouping Mycoplasma isolates prior to definitive identification by serological or other means.


Rapid quantitative method for Salmonella detection in polluted waters. A procedure has been developed for the enumeration of salmonellae in polluted waters using several modifications of existing techniques. Confirmation of salmonellae is achieved within 48 hr. This procedure includes selective enrichment in m-Tetrathionate Broth (22 +/- 1 hr), plating on Brilliant Green Sulfa Agar (20 +/- 1 hr), and confirmation by flagellar (H) agglutination of the growth in a mannosecontaining medium (6 +/- 1 hr). An incubation temperature of 41.5 C was used throughout this procedure. Dilution to extinction techniques (most probable number) were employed to enumerate salmonellae. Large sample volumes were concentrated through the use of membrane filters. This technique proved to be rapid and reliable for the enumeration of salmonellae in water, waste water, and waste-water sludges.


Factors which influence synergism by neomycin and oxytetracycline. Six strains of enteropathogenic gram-negative bacteria were tested for susceptibility to neomycin or oxytetracycline alone and combined in fixed ratios. The minimal inhibitory concentration for the combination was less than one-half of that expected if the antibiotic activities were simply additive. Neomycin alone was more effective against bacteria multiplying in the presence of abundant oxygen, whereas oxytetracycline alone was more effective against bacteria multiplying in relatively anaerobic environments; when combined, the antibiotics complemented each other by their opposing optima for activity. Oxygen concentration, pH, and neomycin activity are related, and the depression of acid production by oxytetracycline is believed to be partially responsible for the synergistic activity of this pair of antibiotics.


Effect of relative humidity on dynamic aerosols of adenovirus 12. Dynamic aerosols of adenovirus 12 were generated in the same Henderson apparatus under conditions of high, medium, and low relative humidity. High relative humidities resulted in more recovery of adenovirus 12 from aerosols and lungs of newborn Syrian hamsters. At 89, 51, and 32% relative humidity, the total infectious virus recovered from a 20-min aerosol was 10(6.7), 10(6.0), and 10(4.3) TCD(50), respectively. Hamsters exposed to these 20-min aerosols retained measured lung doses of 10(3.0), 10(2.4), and 10(1.0) TCD(50), respectively. The measured retained lung doses were compared to calculated inhaled lung doses based on both total virus aerosolized and total virus recovery from the aerosols.


Hospital sanitation: the massive bacterial contamination of the wet mop. Following the demonstration of massive spread of bacterial contamination throughout the hospital by the wet-mopping techniques in use, quantitative studies were undertaken to determine the source of contamination and to institute measures of control. It was found that mops, stored wet, supported bacterial growth to very high levels and could not be adequately decontaminated by chemical disinfection. Laundering and adequate drying provided effective decontamination, but build-up of bacterial counts occurred if mops were not changed daily or if disinfectant was omitted from the wash-water. Recommendations were based upon the experimental findings.


R-factor transfer in selenite and tetrathionate broths. After overnight incubation of R(+)Escherichia coli with R(-)Salmonella typhimurium in selenite and tetrathionate with Brilliant Green (TBG) broths, R-factor transfer was demonstrated in 10 of 12 experiments. R-factor transfer in these enrichment broths occurred at a markedly reduced frequency in comparison to that in Trypticase soy broth, apparently due to an adverse effect either on the viability of the donor E. coli or the conjugation process itself. Transfer of R factors in commonly used enrichment broths may give rise to falsely resistant antibiotic patterns in Salmonella. However, the frequency of R-factor transfer is so low that it is unlikely to affect significantly the interpretation of R-factor studies.


Method for measuring mineralization in lake sediments. A method is described for measuring the mineralization of an organic solute ((14)C-glucose) by the heterotrophic indigenous bacteria in lake sediments. Since there is no suitable procedure for the determination of in situ microbial activities in sediments, the procedure described is probably the best devised so far and may serve as a base for a more definitive procedure.


In vitro studies of semisynthetic alpha-(substituted-ureido) penicillins. The activity of three alpha-(substituted-ureido) penicillins was evaluated in vitro against 599 clinical isolates of gram-negative bacilli, by use of the broth-dilution technique. At a concentration of 12.5 mug or less/ml, BL-P1597 inhibited 90% of isolates of Pseudomonas sp., 56% of Enterobacter sp., 67% of indole-positive Proteus spp., 72% of Escherichia coli, and 85% of Proteus mirabilis. BL-P1654 had similar activity, whereas BL-P1532 was much less active. At a concentration of 25 mug or less/ml, BL-P1597 also inhibited nearly 60% of isolates of Klebsiella sp. and nearly 40% of Serratia sp. BL-P1597 and BL-P1654 were as active as ampicillin and carbenicillin against E. coli and P. mirabilis. They were less active than carbenicillin against indole-positive Proteus spp. Both drugs were substantially more active than carbenicillin against Pseudomonas sp. A strain of Pseudomonas sp. which developed resistance to carbenicillin also developed resistance to the alpha-(substituted-ureido) penicillins simultaneously.


Prophage induction in lysogenic Escherichia coli with simple hydroxylamine and hydrazine compounds. The prophage-inducing capability of hydroxylamine sulfate and 36 of its derivatives, and of hydrazine dihydrochloride and dihydrazine sulfate and 43 of their derivatives, was determined in Escherichia coli W1709 (lambda). Maximal nontoxic concentrations up to 1 mg/ml were tested. Hydroxylamine sulfate was active at 2.5 mug/ml and the following 17 derivatives were active at concentrations ranging up to 500 mug/ml: alpha-naphthylhydroxylamine, N-hydroxy-2-aminofluorene, oxamyl hydroxamic acid, O-carbamoyl hydroxylamine (isohydroxyurea), N-hydroxyurethane, N-methylhydroxylamine HCl, salicylhydroxamic acid, oxalohydroxamic acid, methoxyamine HCl, ethoxyamine HCl, N, N-diethylhydroxylamine oxalate, formaldoxime, formamidoxime, acetohydroxamic acid, acetaldoxime, acetone oxime, and hydroxyguanidine sulfate. Hydrazine dihydrochloride and dihydrazine sulfate were effective inducers at 5.0 and 2.5 mug/ml, respectively, and the following nine derivatives of them were active at concentrations ranging up to 500 mug/ml: phthalic acid hydrazide, phenylhydrazine HCl, p-nitrophenylhydrazine, p-chlorophenylhydrazine HCl, formylhydrazine, carbohydrazide, semicarbazide HCl, 1-methyl-1-phenyl-hydrazine sulfate, and acetic acid hydrazide. Nineteen hydroxylamine and 34 hydrazine derivatives were ineffective as inducers. Application of the prophage-induction system as a tool for detection of responsive hydroxylamino and hydrazino compounds which may be potential toxicological hazards in the environment is discussed.


New method for evaluating antibacterial activity directly on fabric. Bacteriostasis of treated fabric was evaluated directly by a colony count made on the treated fabric after impregnation with seeded agar containing triphenyltetrazolium chloride and incubation in a horizontal, suspended position in a petri dish.


Preliminary report of a new system for typing Salmonella typhimurium in the United States. A new system is described for the bacteriophage typing of Salmonella typhimurium cultures isolated in the United States. The system is based upon one phage adapted to different S. typhimurium strains.


Lactic acid utilization by the cutaneous Micrococcaceae. Human cutaneous staphylococci and micrococci utilized lactic acid as an energy source on a minimal medium. Propionic acid was not utilized, but l(+)-lactic acid and pyruvic acid could replace ld-lactic acid as a substrate. Selected strains of cocci were inhibited more by the l(+) and d(-) forms of lactic acid than the balanced ld form, particularly at pH 5.6. With proper dilution of substrate, lactic acid was utilized by selected strains in the presence of 10 mug of oleic and palmitic acids per ml.


The diagnosis of lung cancer in the 19th century.


Penicillin, ampicillin and cephaloridine in severe exacerbations of purulent chronic bronchitis in elderly patients.


Failure of M. gallisepticum infection to predispose chickens to coliform pericarditis.


"Ophthalmic ice age".

"Ophthalmic ice age".


Sodium ion binding to pepsin and other proteins.


Modification of intrapulmonary blood shunt by end-- expiratory pressure application in patients with acute respiratory failure.


Dip-inoculum urine culture.

Dip-inoculum urine culture.


The reactivity of the N-terminal isoleucine of alpha-chymotrypsin as a function of ionic strength.


Influence of bursectomy on cellular changes in the spleen of immunized chickens. II. A long-term study of the effects of bursectomy.


Some questions of non-H-2 transplantation tolerance in mice.


Issachar Zacharie (1827-1900). A chiropodist of the 19th century.


Quick-response capacity in mice recently immunized to sheep erythrocytes: dependence on a transient cell population.


Cat scratch disease.

Cat scratch disease.


Comments on epidemiologic aspects of feline leukemia virus.


Epidemiologic implications of feline leukemia virus.


An immunofluorescent test for feline leukemia and sarcoma virus antigens and antibodies.


Treatment of leukemia in the cat.

Treatment of leukemia in the cat.


Virologic and immunologic aspects of feline picornaviruses.


Microbiological and immunologic aspects of feline pneumonitis.


Experimental production of urolithiasis in male cats.


Microbial studies of feline urolithiasis.


High resolution autoradiography with stripping film.


Experimental wound repair in the black abalone, Haliotis cracherodii.


[Toxins of the entomophagous fungus Beauveria bassiana. II. Effect of nitrogen sources on formation of the toxic protease in submerged culture].


A bacterium and dipterous parasite in wild populations of cowpea curculio larvae: effects of treatment with spores of Metarrhizium anisopliae.


W. Charles Miller, MD., President 1970-1971.


Design of partial denture components. I. Middle palatal bars.


Studies on dental aerobiology. II. Microbial splatter discharged from the oral cavity of dental patients.


Assay of tRNA methylase enzymes in studies of malignant transformation in vitro.


Glutaminase induced prolonged regression of established Ehrlich carcinoma.


Introduced articulator error.

Introduced articulator error.


Are heart transplants really justified?

Are heart transplants really justified?


Analysis of heart rate in dogs during retraction and impression procedures.


A bibliography of actinomycosis.

A bibliography of actinomycosis.


Acid-base balance computer for teaching and clinical applications.


Influence of Candida albicans glycoprotein on 3-methylcholanthrene induced malignancy in newborn rodents.


The effect of unconjugated bilirubin and some bilirubin precursors on cell culture.


Recognition and differential diagnosis of Erwinia herbicola strains isolated in the hospital.


Anaerobic digestion in biological waste treatment.


East Harlem: an initial view.

East Harlem: an initial view.


Rumen micro-organisms.

Rumen micro-organisms.


The industrial potential of plant cell culture.


Tobacco smoke: a noxious air pollutant. A review (and comment). I of II.


Tobacco smoke: a noxious air pollutant. A review (and comment). II of II. Tobacco smoke: general characteristics and composition.


Evolving social services in psychiatry.

Evolving social services in psychiatry.


Giant follicular lymphoma of kidney: arteriographic findings.


Are plastids autonomous?

Are plastids autonomous?


Origin of plastids: cytological results and interpretations including some genetical aspects.


Teaching--or preaching--the behavioral sciences.


Information content in the chloroplast DNA.


Nucleus, cytoplasm and cell.

Nucleus, cytoplasm and cell.


Developmental interactions among cellular compartments in Euglena.


Synthesis of RNA in Acetabularia.

Synthesis of RNA in Acetabularia.


The autonomy of nuclear activity in multicellular organisms.


Organelle integration and the evolution of ribosome structure and function.


Some hazards of methotrexate treatment of psoriasis.


Three cases of phycomycosis in dogs.

Three cases of phycomycosis in dogs.


A "soap trial" for the treatment of erythrasma.


The place of medical laboratory technology in the practice of medicine.


Clinical evaluation of xanthinol nicotinate ("complamin") in Nigerians with cerebral thrombosis.


Persistent urinary tract infection with Salmonella typhimurium after renal cadaveric transplantation.


The liquid movement in desiccated and rehydrated dentine in vitro.


Problems in larynx homotransplantation.

Problems in larynx homotransplantation.


Investigations on the response of some lysosomal enzymes of rabbit leukocytes in the course of immunization with allogenic skin graft.


Pulmonary aspiration.

Pulmonary aspiration.


Trimethoprim plus sulphamethoxazole compared with chloroquine in the treatment and suppression of malaria in African schoolchildren.


Insect cell and tissue culture.

Insect cell and tissue culture.


Myxovirus ribonucleic acids.

Myxovirus ribonucleic acids.


New approaches in the management of fulminant hepatic failure.


Diseases of the chest during the past twenty-five years.


A pilot trial of methisazone in infectious mononucleosis and chcikenpox.


The controlled evaluation of a new tranquillizing drug medazepam in the treatment of anxiety.


Birmingham's baby: the beginnings of medical education in Rhodesia.


Treatment of phobias.

Treatment of phobias.


Candida and dentures.

Candida and dentures.


Case of Plasmodium vivax malaria contracted in Southern Europe.


Prostaglandin-induced labour.

Prostaglandin-induced labour.


Meningomyelocele: the price of treatment.


Malformations of central nervous system and softness of local water supplies. The mean annual prevalence at birth of congenital malformations of the central nervous system for the three years 1964-6 in 48 local authority areas in South Wales was negatively correlated (r = -0.402, P<0.01) with estimates of the mean total hardness of the related water supplies.The mean annual perinatal mortality rate from anencephalus for the five years 1963-7 in 58 county boroughs in England and Wales was also negatively correlated with estimates of the mean total hardness (r = -0.220, P>0.05) and calcium content (r = -0.289, P<0.05) of the related water supplies.It is concluded that the relationship between these associations may well be secondary. Analytical epidemiological studies of the association are called for.


Study of cytotoxic chemotherapy as an adjuvant to surgery in carcinoma of the bronchus. Report by a Medical Research Council Working Party. This report gives the findings after two years of a study of long-term oral cytotoxic chemotherapy with busulphan or cyclophoshamide in carcinoma of the bronchus compared with two placebos, identical in appearance to the drug-containing tablets. A total of 753 patients who had had a total resection of the tumour, who had no detectable extrathoracic metastasis, and who were able to attend chest clinics monthly were admitted to the study from January 1965 to January 1968. Twenty-seven patients were excluded from all the analyses.The 217 patients admitted up to December 1965 form the "early" intake, the remaining 509 the "late" intake. There were no significant differences between the series in either intake period in a number of pretreatment factors studied. At 24 months 46% of the busulphan, 44% of the cyclophosphamide, and 49% of the placebo series were alive in the early intake, as were 49%, 50%, and 50% respectively in the late intake. There were no important differences between the series in survival related to pretreatment condition, cause of death, time of detection of metastases, and condition of the survivors at 24 months. Maintenance chemotherapy was interrupted to a greater extent in the busulphan than in the cyclophosphamide series and least in the placebo series.In both intakes clinical toxicity was more frequent in the cyclophosphamide series and similar in frequency in the busulphan and placebo series. Haematological toxicity was particularly frequent and severe in the busulphan series, especially in the early intake, platelet depression being the predominant manifestation.It is concluded that there is no evidence that either of the two cytotoxic drugs in the dosage prescribed improved survival for the two-year period of observation, though a final evaluation of the adjuvant chemotherapy as studied in this investigation will have to await the results at five years.


Diverticular disease of the colon: a deficiency disease of Western civilization.


Herbert Bruce MacEwen.

Herbert Bruce MacEwen.


Treatment of Salmonella enteritis and its effect on the carrier state. During an outbreak of Salmonella enteritis, 113 symptomatic and asymptomatic patients were assigned to different treatment groups: 43 received ampicillin; 41 were given trimethoprim-sulfamethoxazole; and 29 received no specific therapy. During the four-week observation period no statistically significant benefit from treatment with either ampicillin or trimethoprim-sulfamethoxazole was apparent in relation to duration and severity of symptoms or duration of the carrier state. However, the impression that trimethoprim-sulfamethoxazole might have shortened the period of fecal Salmonella excretion in the few asymptomatic patients may warrant further controlled studies.There was no significant alteration in hematological or biochemical values, or urine constituents, in patients receiving trimethoprim-sulfamethoxazole. Side effects probably attributable to this drug developed in only 5% of the 41 patients.It is concluded that uncomplicated salmonellosis is best treated without using currently available chemotherapeutic agents.


Serratia marcescens endocarditis. A report of a case involving Cross-Jones mitral valve prosthesis, with a review of the literature.


Renal tubular transport of amino acids.

Renal tubular transport of amino acids.


The inhibitory action of transfer factors on lysis of Escherichia coli K12 by phages mu 2 and phi 2.


Change of host range in a resistance factor.


Selection of the number and positions of measuring locations for electrocardiography.


Dipole, quadripole, and octapole measurements in isolated beating heart preparations.


Physical arrangements at the bedside in support of automated systems for patient care.


Immunization.

Immunization.


An instrument for separation of multiple-unit neuroelectric signals.


An electronic isopotential mapper.

An electronic isopotential mapper.


Conquest of deficiency diseases achievements and prospects.


Differential gene activation in isolated chromosomes.


Neurilemomas of peripheral nerves.

Neurilemomas of peripheral nerves.


Immediate unrestricted activity after operation. With particular reference to 11,272 inguinal herniorrhapies using local anesthesia.


Richard Ho Ping Sia, M.D. 1895-1970.

Richard Ho Ping Sia, M.D. 1895-1970.


Significance to health of mercury used in dental practice: a review. Council on Dental Materials and Devices. Council on Dental Research.


Influence of chromosome structure on the frequency of tonB trp deletions in Escherichia coli. The frequency of tonB trp deletions varies in different strains and substrains of Escherichia coli. Studies with chromosomal hybrids constructed by transducing various segments of the cysB-trp-suIII region from K-12(Ymel) into K-12(W3110) indicate that the characteristic low deletion frequency of K-12(Ymel) is determined largely by the (genetic) structure of the trp-suIII region of the chromosome. Transduction of the trp region from K-12(W3110) or K-12(Ymel) into strain B has little effect on the frequency of tonB trp deletions in that strain. When tonB trp deletions occur at 42 C rather than at 37 C, there is a significant reduction in the frequency of deletions in all strains examined except K-12(Ymel) and hybrids exhibiting a Ymel deletion pattern. The magnitude of this temperature effect in different K-12 strains increases proportionally with the frequency of tonB trp deletions at 37 C. At 42 C the frequency of tonB trp deletions in all K-12 strains approaches the low frequency observed for Ymel at 37 or 42 C. In contrast, spontaneous deletions in another region of the genome which simultaneously result in resistance to phages T7 and lambda and in proline auxotrophy (tfrA pro deletions) occur at a constant frequency regardless of growth temperature or the structure of the chromosome in the trp region. Two mutants of strain KB30 obtained after treatment with nitrosoguanidine show very low tonB trp deletion frequencies. The alterations in both mutants map in the trp region of the chromosome. These studies indicate that the structure of the cysB-trp-suIII region is responsible for many of the characteristic deletion frequencies observed.


Proline biosynthesis: regulation by a positive control mechanism?


Synthesis of ribosomes in a mutant of Escherichia coli.


Relation of dipicolinic acid to heat resistance of bacterial spores.


Formation and properties of T factor complexes.


Molar growth yields and fermentation balances of Lactobacillus casei L3 in batch cultures and in continuous cultures.


Properties of male derivatives of Escherichia coli mutants defective in initiation of chromosome replication.


The synthesis of ribosomes in bacteria.

The synthesis of ribosomes in bacteria.


The timing of episomal F replication in Escherichia coli at different growth rates.


A mutant in the initiation of DNA synthesis in Salmonella typhimurium.


Suppressor transfer RNAs and their use in the study of tRNA structure and function.


Effects of purine nucleotide concentrations on RNA synthesis in Escherichia coli.


The fate of nucleic acids during mixed infections with bacteriophages.


Production of DNA-less cells in a mutant of Salmonella typhimurium.


Rate of DNA replication in thymine-requiring strains of Escherichia coli.


The thymidine triphosphate pool in wild-type and thymine requiring strains of Escherichia coli K 12 and 15.


Pyrimidine sequences in the complementary strand of the replicative form of bacteriophage phi-X174 DNA.


The accumulation of ribosome precursors during inhibition by cobalt chloride.


Altered ribosomes after inhibition of Escherichia coli by rifampicin.


A rapid dilution technique.

A rapid dilution technique.


Mouse virulence of Salmonella strains: the effect of different smooth-type O side-chains.


Induction of DNA breakdown and inhibition of cell division by colicin E2. Nature of some early steps in the process and properties of the E-2-specific nuclease system.


Anaerobiosis and the activity of enzymes of pyrimidine biosynthesis in Staphylococcus aureus.


Resistance pattern and genetics of erythromycin-resistant mutants of Streptococcus pyogenes.


William Osler (1849-1919); book lover and writer.


An outbreak of lead poisoning of bread in Malta. Interesting association with British naval history.


Naval medical ceramics.

Naval medical ceramics.


Diagnostic nuclear medicine, today and tomorrow.


An evaluation of periodic screening of breast cancer patients.


Changing concepts of treatment in acute leukemia.


Proliferation and differentiation of gastrointestinal cells in relation to therapy.


Reminiscence and experience in experimental chemotherapy of cancer.


The training of internists in cancer.

The training of internists in cancer.


A current trend in palaeoanthropology.

A current trend in palaeoanthropology.


Biochemical research in schizophrenia.

Biochemical research in schizophrenia.


Prebiotic formation of cytidine nucleotides.


Incorporation of high molecular weight polynucleotides by isolated mitochondria.


Flux ratios and isotope interaction in an ion exchange membrane.


Frequency of polyploid spermatozoa in man.


Sex difference in the number of adipose cells from genetically obese rats.


A lung oedema factor from mouldy sweet potatoes (Ipomoea batatas).


Mechanism of insecticide-induced diuresis in Rhodnius.


Fusaric (5-butylpicolinic) acid, an inhibitor of dopamine beta-hydroxylase, affects serotonin and noradrenaline.


Birth order of psychiatric patients.

Birth order of psychiatric patients.


Basic rectangle of the mandible in the Hominoidae.


Retrieval of information after use of marihuana.


Pollution is a dirty word.

Pollution is a dirty word.


Semi-in-vivo?

Semi-in-vivo?


Expensive meat.

Expensive meat.


Dr. Geoffrey Bourne.

Dr. Geoffrey Bourne.


Academy squirms a little in sudden spotlight.


The quantitative effect of pelleting feed on the performance of piglets and fattening pigs.


A diathermy catheter with internal fixation for bladder drainage after prostatectomy.


The rebel and the conservative in the history of medicine.


The pathogenesis of the immunologic granuloma.


Georges Clemenceau, M.D. (1841-1929). The smile on the face of the "Tiger".


Membrane structural proteins.

Membrane structural proteins.


Physiology of the choroid plexus.

Physiology of the choroid plexus.


Integrative neural cardiovascular control.


Oral manifestations of systemic genetic disorders. 4.


Developmental approach in the analysis of roentgenograms of the pediatric skull.


Regulation of enzyme activity. The activity of enzymes can be controlled by a multiplicity of conformational equilibria.


Obesity--the health hazard of our time.

Obesity--the health hazard of our time.


X-ray diffraction patterns of transfer RNA consistent with the presence of short parallel helices in the molecule. X-ray diffraction data of yeast formylmethionine transfer RNA, Escherichia coli phenylalanine transfer RNA, and Escherichia coli arginine transfer RNA single crystals are compared with the Fourier transform of a helix. The results are consistent with the presence of short parallel double helical segments in the transfer RNA molecules.


II. Major tranquilizers.

II. Major tranquilizers.


Recent advances in the treatment of lymphedema.


Newer trends in the diagnosis and treatment of bronchogenic carcinoma.


Recent diagnostic advances in obstructive jaundice.


The relationship of gastrointestinal tumors to diarrhea.


Advances in the management of surgical wounds.


Joseph's rhinoplasty with some modifications.


Alternative methods in arterial reconstruction.


The pathological anatomy of muscle diseases.


Studies on antibody production in uraemia.


2-(2.6-dichlorophenylamino)-2-imidazoline hydrochloride (ST 155 or Catapresan) as a prophylactic remedy against migraine.


Heredity in Duane's syndrome.

Heredity in Duane's syndrome.


Observations on the blood vessels of the pig iris.


Renal transplantation in rabbits. IV. Morphological alterations in allografts from recipients presensitized by multiple skin grafts.


Renal transplantation in rabbits. V. Morphological alterations in allografts from recipients presensitized by donor kidney homogenate.


Natural history of spina bifida cystica and cranium bifidum cysticum. Major central nervous system malformations in South Wales. IV.


Postoperative care of patient undergoing cardiopulmonary bypass.


Anaesthesia for diagnostic procedures in cardiac disease.


Lithium prophylaxis in recurrent affective disorders.


Lithium prophylaxis recurrent affective disorders.


A contribution to the history of the psycho-analytic movement in Britain.


Bi-frontal stereotactic tractotomy. A follow-up study of its effects on 210 patients.


The effect of x-rays on circulating lymphocytes of mice quantitated by PHA-responsiveness.


Chemotaxis of polymorphonuclear leucocytes from germ-free rats and generation of chemotactic activity in germ-free rat sera.


Cytogenetics of gynecologic neoplasms.

Cytogenetics of gynecologic neoplasms.


Biologic and clinical implications obtained from the analysis of cancer growth curves.


Significance of dysplasia.

Significance of dysplasia.


The problem of optimal management of cervical carcinoma in situ.


Tuberculosis of the female genital tract.


A comparator method of assessing bacterial plate counts.


A study of the effect of carbon dioxide on the germination and outgrowth of spores of spores of Clostridium butyricum using a slide culture technique.


Studies on freshwater bacteria: effect of medium composition and method on estimates of bacterial population.


Improved synthetic medium for the growth of Rhizobium.


A note on the development of resistance to heat and gamma radiation in Salmonella.


Adenosinetriphosphate (ATP) levels in foods contaminated by bacteria.


Differential immunofluorescence of fertilized mouse eggs with H-2 and non-H-2 antibody. Mouse embryos at the two-cell and blastocyst stages, as well as unfertilized eggs, have been studied by indirect immunofluorescence for the expression of H-2 and non-H-2 histocompatibility antigens on surface membranes. Serologically-specific reactivity to non-H-2 antibody (H-3 and H-6) was observed as diffuse, patchy staining over the entire surface of the blastomeres at the two-cell stage. In contrast, no reactivity of two-cell or unfertilized egg embryos of four inbred strains was observed when antisera containing only multispecific H-2 cytolytic antibody were used. Antisera containing H-2 along with non-H-2 antibody of unknown specificity showed varying degrees of reactivity, which could be shown by absorption studies to be due to the non-H-2 content of the serum. The results suggest that the initial expression of histocompatibility genes varies and support the hypothesis that the appearance of these cell components may relate to specific stages of differentiation.


Formulation of cell growth inhibition by chemicals and environmental agents.


The genetic relatedness of proteolytic Clostridium botulinum strains.


Replication of bacteriophage M13. V. Single-strand synthesis during M13 infection.


Effect of the rel locus on Qbeta RNA synthesis.


Replication of gene 46-47 amber mutants of bacteriophage T4D.


Synthesis and breakdown of proteins in Escherichia coli during amino-acid starvation.


Ahmad-Zadeh C,+AHMADAAZADEH C: Internal proteins of bacteriophage T4D: their characterization and relation to head structure and assembly.


Simpson. The man and his discoveries.

Simpson. The man and his discoveries.


Nephropathy of secondary syphilis. A clinical and pathological spectrum.


The bicentennial of the New York Hospital (1771-1971).


Vitamin B 12 absorption tests. Their unreliability in postgastrectomy states.


A comparative trial of doxepin and amitriptyline in depressive illness.


Allan Edward Duxbury.

Allan Edward Duxbury.


Oral effects of hydrolytic enzymes on taste acuity in man.


William Joseph MacDonald.

William Joseph MacDonald.


Margaret Jennifer Howitt.

Margaret Jennifer Howitt.


Tearing out of peritoneal suture.

Tearing out of peritoneal suture.


Adaptation to high altitude.

Adaptation to high altitude.


Treatment of the idiopathic respiratory-distress syndrome with continuous positive airway pressure.


Corticosteroid therapy in severe alcoholic hepatitis. A double-blind drug trial.


Of HMD, ICU's, CPAP and Jenner.

Of HMD, ICU's, CPAP and Jenner.


Preventable drug reactions--causes and cures.


Diagnosis via plus and sort.

Diagnosis via plus and sort.


Alcoholic hepatitis.

Alcoholic hepatitis.


Preservation of functional mammalian polysomes by lyophilization.


Is Kornberg junior enzyme the true replicase?


Coordination of sex pili with their specifying R factors.


Elevation of serum dopamine-beta-hydroxylase activity with forced immobilization.


Origins of electrotherapy. II.

Origins of electrotherapy. II.


Lymphoproliferative disease secondary to breast cancer.


Jean Paul Marat, M.D. (1743-1793). Physician turned radical.


The diagnosis of pulmonary embolism: a review with particular reference to the use of radionuclides.


Primary lymphosarcoma of the stomach.

Primary lymphosarcoma of the stomach.


Massive kidney allograft rejection without oliguria.


Histopathological changes in canine renal allotransplants after yeast respiratory extract (PCO) treatment.


Our experience in associated immunotherapy of cancer.


Mode of action of beta-chelocardin.

Mode of action of beta-chelocardin.


Polycyclic aromatic hydrocarbons. Covalent binding to DNA and effects on template function.


Language skills of cleft palate children: a review.


Accuracy of indirect stone models made from reversible hydrocolloid impressions.


Virus-like particles in abnormal cells of Saccharomyces carlsbergensis.


Walter Palmer Thompson. 1889-1970.

Walter Palmer Thompson. 1889-1970.


Immunological significance of changes in lymph nodes across the leprosy spectrum.


The genetic basis of autoimmunity in NZB mice studied by progeny-testing.


Heterologous antiserum against gastric parietal cells induced by sub-microsomal gastric mucosal fraction.


Studies on the anti-tumour activity of aliphatic aldehydes. IV. Radiosensitizing properties of L-erythro-alpha, beta-dihydroxybutyraldehyde on E. coli B and Ehrlich ascites tumour cells.


Conquest of deficiency diseases achievements and prospects. 3. Pellagra.


Comparative study of new low-dosage pills for oral contraception in Indian women.


The removable cast orthodontic retainer.


Method for posttreatment evaluation of the quality of dental care.


The current status of certifying examinations in Dental Public Health.


Dynamic transition in dentistry; expanded functions for auxiliaries.


The influence of elevated venous pressure on blood-tissue exchange of 22Na in perfused hindlimbs of dogs.


A review of cord traction in the third stage of labour from 1963 to 1969.


Vitamin C (L-ascorbic acid and dehydro-L-ascorbic acid). A contribution to the Captain Cook bicentennial celebrations.


A museum of medical history for Sydney?

A museum of medical history for Sydney?


The absorption of topical corticosteroids, with particular reference to percutaneous absorption in infancy and childhood.


Crying wolf in the dark.

Crying wolf in the dark.


Crying halt in Britain.

Crying halt in Britain.


New wing for high flyer.

New wing for high flyer.


Sink or swim.

Sink or swim.


St George versus a gypsy moth.

St George versus a gypsy moth.


Hypsilophodon, the cursorial non-arboreal dinosaur.


Role of subunits in the ribosome cycle.

Role of subunits in the ribosome cycle.


Specific autostimulating factor released by lymphocytes.


Antigen-binding small lymphocytes in delayed hypersensitivity to tuberculin.


Chromosomal evidence for natural interspecific hybridization by mosquitoes of the Anopheles gambiae complex.


Blood concentration of noradrenaline in the dog after intravenous administration and the effects of desipramine.


Model for the action of tetrodotoxin and batrachotoxin.


Molecular mechanisms of storage of transmitters in synaptic terminals.


Effect of microamp electrical currents on bone in vivo and its measurement using strontium-85 uptake.


Ramapithecus wickeri mandible from Fort Ternan, Kenya.


Chromosomal and serological studies of the Caenolestidae and their implications for marsupial evolution.


Suppression of fighting behaviour in rabbits by paired emergence from anaesthesia.


Energy for meat.

Energy for meat.


Beans means meat.

Beans means meat.


PSAC hiccoughs over 2,4,5-T.

PSAC hiccoughs over 2,4,5-T.


Early man in the East Rudolf basin.

Early man in the East Rudolf basin.


New centre for biologists.

New centre for biologists.


Release of noradrenaline from sympathetic endings.


Further evidence of lower Pleistocene hominids from East Rudolf, North Kenya.


Vertebrate faunas from the Kubi Algi, Koobi Fora and Ileret areas, East Rudolf, Kenya.


Geographical variation in the Atlantic salmon.


Effects of marihuana on the solution of anagrams, memory and appetite.


Electron energy loss spectra of the nucleic acid bases.


Electron microscopic studies of lipid protein films.


Definition of cancer research.

Definition of cancer research.


Dietary fat and carbohydrate induction of hyperlipemia.


Blood glucose and diabetes mellitus.

Blood glucose and diabetes mellitus.


Vitamin A and the synthesis of a lipid containing mannose in rat liver.


Dietary obesity in seven strains of rats.


Diet induced changes in hexosemonophosphate dehydrogenases and RNA metabolism.


Caloric balance in rats at high altitude.


The effects of malnutrition of specific amino acids in the serum.


Nutritional trace element research.

Nutritional trace element research.


Hypomagnesemia in protein-calorie malnutrition.


Vitamin E and heme synthesis in the rat.


Biotin and protein biosynthesis.

Biotin and protein biosynthesis.


Metals as constituents of enzymes.

Metals as constituents of enzymes.


Relationship of mental disorder to suicidal behavior. Review of recent issues.


Paranoia and homosexuality. Schreber reconsidered.


Malaria acquired in United States. Introduced and cryptic.


Detection of salmonellae in frozen poultry products using the Banwart flask.


Egg white catalase. 2. Active component.


Antibacterial activity of sulfadimethoxine potentiated mixture (Rofenaid) in turkeys.


The onset and development of the chick electroretinogram: the A- and B-waves.


Effects of methionine and valine on growth and antibody production in chicks infected with live or killed Newcastle disease virus.


Vaccination against measles. Clinical trial of live measles vaccine given alone and live vaccine preceded by killed vaccine. Third report to the Medical Research Council by the Measles Vaccines Committee.


Advantages of prednisolone stearoylglycolate in chronic steroid-dependent asthma.


Clinical trial of fluphenazine in the post-concussional syndrome.


Discussion on control of new drugs.

Discussion on control of new drugs.


Treatment of migraine.

Treatment of migraine.


Mrs. Somerville's husband. William Somerville, M.D., F.R.S.


Respiratory failure in myasthenia gravis.


Beethoven's illness-a likely diagnosis.

Beethoven's illness-a likely diagnosis.


Ludwig van Beethoven.

Ludwig van Beethoven.


Transferable antibiotic resistance in Escherichia coli.


Treatment of cysts of the jaws.

Treatment of cysts of the jaws.


Management of pigmented lesions in childhood.


Vascular isolation in treatment of juxtahepatic venous injuries.


Complete axillary node dissection with preservation of the pectoralis major muscle.


Intermittent positive pressure and extrathoracic assisted breathing in hypovolemia. Comparative hemodynamic effects.


Extended tracheal resection with end-to-end anastomosis.


Successful three- to seven-day preservation of canine kidneys. Immediate life-sustaining function.


Hemodialysis in children. Experience with arteriovenous shunts.


Review of bovine vibriosis.

Review of bovine vibriosis.


Body-section radiography: history, image information, various techniques and results.


The dependence of hippocampal function on extracellular potassium levels.


Inhibition by hydrazine, phenelzine and pargyline of insulin release from rat pancreas.


Growth hormone secretion in young rats after partial or total interruption of neural afferents to the medical basal hypothalamus.


Inhibition of glucose and tolbutamide-induced insulin release by iodoacetate and antimycin A.


Short latency induction of estrous behavior with intracerebral gonadal hormones in overiectomized rats.


Diagnosis of rabies in dogs--comparative study on microscopic, biological and fluorescent antibody tests for diagnosis.


Effect of tetranucleoside triphosphates on the binding of aminoacyl transfer RNA to ribosomes.


Diagnostic ultrasound in clinical thyroid investigation.


Acute effects of intravenous infusion of 17-beta-estradiol on gonadotropin release in pre- and post-menopausal women.


Lack of response of serum growth hormone to metyrapone.


'An arte to make the dumbe to speake, the deafe to heare': a seventeenth-century goal.


Paulesco and the isolation of insulin.

Paulesco and the isolation of insulin.


The amphetamine inhaler: a case study of medical abuse.


Descartes and the ECG lettering series.

Descartes and the ECG lettering series.


Benjamin Smith Barton, M.D. (Kiel).

Benjamin Smith Barton, M.D. (Kiel).


Reduction of a dislocated joint. Artist unknown. Early- to mid-nineteenth century New Haven, Yale Medical Library, Clements C. Fry Collection.


Embryological drawings concerning his Theorie von der Generation sent by Caspar Friedrich Wolff to Albrecht von Haller in 1764.


Studies on convulsive disorders in young children. II. Intermittent phenobarbital prophylaxis and recurrence of febrile convulsions.


Studies of the school-age child with meningomyelocele: social and emotional adaptation.


Heterogeneity of phenotypic expression in a family with Swiss-type agammaglobulinemia: observations on the acquisition of agammaglobulinemia.


Electron microscopic virus-like material in systemic lupus erythematosus: with preliminary immunologic observations on presence of measles antigen.


An approach to the lower third of the ureter.


Pull-through ureteral reimplantation for reflux.


Involvement of the bladder in leukemia and lymphoma.


Urinary diversion by anterior transposition of the urethra.


Anterior urethral transposition: a modification of technique.


Computer diagnosis of congenital heart disease by means of vectorcardiogram (VCG).


Effect of high pressure perfusion of the kidney on the systemic blood pressure in normotensive and hypertensive dogs.


Inhibition of phage growth by an antibiotic rugulosin isolated from Myrothecium verucaria. I. Properties of the anti-phage effect.


Effects of acute hypoxia on the pulmonary vascular bed in man.


Inhibition of phage growth by an antibiotic rugulosin isolated from Myrothecium verucaria. II. The mechanism of action.


Autolytic enzyme system of Clostridium botulinum. II. Mode of action of autolytic enzymes in Clostridium botulinum type A.


Adjuvanticity of mycobacterial cell walls.


Cellular mechanisms of adjuvant action of bacterial lipopolysaccharide in anti-sheep red blood cell antibody response.


A new mucolytic, bromhexine ("bisolvon"). A double-blind study.


Doctors' fees and costs.

Doctors' fees and costs.


Sustained release aspirin.

Sustained release aspirin.


Lucidril for autism.

Lucidril for autism.


Computer systems for electrocardiographic analysis.


An adventurous voyage to the Far East in 1761-1765.


Colors of the newborn.

Colors of the newborn.


Eugene Maximilian Karl Geiling.

Eugene Maximilian Karl Geiling.


William H. Harridge, 1919-1971.

William H. Harridge, 1919-1971.


Miss Ella Maude Salmonsen, 1896-1971.

Miss Ella Maude Salmonsen, 1896-1971.


New aspects on transferable drug resistance.


Salmonella infection in fattening calves after slaughter.


Enterotoxic activity of whole cell lysates of Escherichia coli in young pigs.


Bactericidal activity of bovine serums against coliform organisms isolated from milk of mastitic udders, udder skin, and environment.


Technique for semipermanent cannulation of ureters in bovine, ovine, porcine, and canine species.


Evidence for a change in certain properties of vaccinia virus after trypsinization: heat inactivation or removal of a postulated trypsin-sensitive inhibitor on virions.


Nonpigmented Serratia marcescens arthritis in a teju (Tupinambis teguixin).


Surgical treatment of coronary artery disease.


In memoriam. David Isaac Arnow, M.D.

In memoriam. David Isaac Arnow, M.D.


In memoriam. John Stanley, M.D.

In memoriam. John Stanley, M.D.


A detergent-polyacrylamide gel system for electrophoretic resolution of membrane and wall proteins.


Ultrastructure of monolayer cultures of pancreatic islet cells.


Evidence for the polycistronic transcription of ribosomal RNA in Escherichia coli.


The transport of methyl-alpha-D-glucopyranoside by thermally stressed Salmonella typhimurium.


Isolation and properties of the FSH and LH-releasing hormone.


Induction of a new RNA polymerase in Escherichia coli infected with bacteriophage T3.


The separation and preparation of human pepsins 3 and 5 from the gastric juice of single individuals, and the mode of action of human and swine pepsins on the B-chain of oxidized insulin.


Relationship between the conformation of bovine serum albumin and its digestion by pepsin.


The fluorescent antibody test as a diagnostic test for canine distemper in naturally infected dogs.


Selective media for the isolation of Brucella ovis.


Ecdysis of haemonchus and hypotheses.

Ecdysis of haemonchus and hypotheses.


Status of the clinical evaluation of levodopa in the treatment of Parkinson's disease and syndrome.


Treatment of Parkinson's disease with levodopa and Ro 4-4602.


Levodopa: alterations in behavior.

Levodopa: alterations in behavior.


Insoluble enzymes. A review.

Insoluble enzymes. A review.


Professor Janina Kowalczykowa. 1907-1970.


Diminished transplantation immunity and parabiotic intoxication under the influence of nonspecific antigenic stimuli.


Acute, reversible respiratory acidosis in cardiogenic pulmonary edema.


Baccalaureate and masters degree programs in nursing accredited by NLN, 1971-2.


Mechanisms in renal hypertension.

Mechanisms in renal hypertension.


The significance of cardiolipin immunofluorescence (CLF).


Use of gnotobiotic pigs for research on enteritis associated with Escherichia coli.


Traumatic quadriplegia. A comprehensive review.


Bursa of fabricius references.

Bursa of fabricius references.


An investigation into some diffraction effects observed in microradiographic images of bone sections.


Hysteria: in search of the animus.

Hysteria: in search of the animus.


The causes of the Scottish medical Renaissance of the eighteenth century.


The quest for certainty in medicine: John Brown's system of medicine in France.


Cutting for the stone in the early Middle Ages.


Healing of the bronchial anastomosis in transplanted lung.


Physiological studies with purified human pituitary FSH (HP-FSH).


Giorgio Vasari's attribution of the Vesalian illustrations to Jan Stephan of Calcar: a further examination.


Reason and emotion in the individual psychology of Adler.


Sensitivity training and Adlerian theory.


Conrad Arnold Elvehjem--a biographical sketch (1901-1962).


A review of the 1970 literature on wastewater and water pollution control.


The DNA replication mystery.

The DNA replication mystery.


What turns plants on?

What turns plants on?


Asian diet.

Asian diet.


Role of the research councils.

Role of the research councils.


Purification of an altered DNA polymerase from an E. coli strain with a pol mutation.


Novel species of tRNA.

Novel species of tRNA.


Determination of hydrocarbons in seawater extracts of crude oil and crude oil fractions.


Neonatally induced allograft tolerance may be mediated by serum-borne factors.


Persistent alteration of turnover of brain noradrenaline in the offspring of rats subjected to stress during pregnancy.


Reduction or disappearance of visual after effect of movement in the absence of patterned surround.


Mouse specific bone marrow-derived lymphocyte antigen as a marker for thymus-independent lymphocytes.


Primary reaction of phytochrome.

Primary reaction of phytochrome.


Coupled oscillatory control mechanism in a planktonic system.


Issels' claims refuted.

Issels' claims refuted.


Food chain model for DDT kinetics in a freshwater marsh.


Medawar's successor.

Medawar's successor.


FDA called unhealthy for science and scientists.


Thirty years after.

Thirty years after.


Developments in molecular energy transfer.


Isolation and identification of sterols from a pleistocene sediment.


Territoriality in the white rhinoceros (Ceratotherium simum) Burchell.


Plants and soils as indicators of metals in the air.


Orbital steering and the catalytic power of enzymes.


Solvophobic interactions and micelle formation in structure forming nonaqueous solvents.


Periodicity of speech in Parkinsonism.

Periodicity of speech in Parkinsonism.


Effect of radiation on the germination of spores of Dictyostelium discoideum.


Effect of L-asparaginase on germinal centre haemolysin.


Enhancement of metastases by L-asparaginase in a mouse tumour system.


Tolerance to a protein antigen in a poikilotherm, the marine toad Bufo marinus.


Evidence that piroplasms can undergo antigenic variation.


Evidence for temporary slowing of mucociliary clearance in the lung caused by tobacco smoking.


Absence of cell sorting out in the grex of the slime mould Dictyostelium discoideum.


Rediscovery of the marsupial Echymipera rufescens in Australia.


Antitranspirant activity of the methyl and phenyl esters of abscisic acid.


Auxin production by phylloplane fungi.

Auxin production by phylloplane fungi.


Human embryology.

Human embryology.


Labour rewarded.

Labour rewarded.


Fishing in common waters.

Fishing in common waters.


What are they there for?

What are they there for?


Rewards for inventors.

Rewards for inventors.


Pressure reversal of anaesthesia.

Pressure reversal of anaesthesia.


Identification of an unusual Y chromosome in YY mosaicism by quinacrine fluorescence.


X chromosome inactivation studied by injection of a single cell into the mouse blastocyst.


Impenetrability of the mouse placenta to maternal leukemia cells.


Homocysteine metabolism in scurvy, growth and arteriosclerosis.


Inhomogeneous refractive index in the crystalline cone of a moth eye.


Metabolic rate independent of temperature in mollusc tissue.


Right hemisphere specialization for depth perception reflected in visual field differences.


Effects of actinomycin D on memory and brain RNA synthesis in an appetitive learning task.


Failure of visual estimation of motion under strobe.


Philadelphia (Ph-1) chromosome.

Philadelphia (Ph-1) chromosome.


The "as if" personality and Anton Chekhov's "The Darling".


Sex norms, emotionality and artistic creativity: psychohistorical explorations.


Laing, Lawrence, and the maternal cannibal.


Notes on Shakespeare's "The Winter's Tale".


Placental infection in the fetuses of pregnant murine leprous mice.


Ernest Hemingway. A psychiatric view.

Ernest Hemingway. A psychiatric view.


Neuropsychological correlates of affective disorders.


Oral lesions.

Oral lesions.


EEG and behavioral effects of drug therapy in children. Chlorpromazine and diphenhydramine.


Marihuana and the temporal span of awareness.


The development of psychiatry in New York City: an overview.


Leprosy through the ages: an exhibit.

Leprosy through the ages: an exhibit.


Glass objects of medical interest at the London Museum.


Diagnostic evaluation of ECG data by a computer.


Systemic dissemination of Pneumocystis carinii pneumonia.


Treatment of intracapsular fracture of the hip with primary pedicle bone graft from greater trochanter.


Surgical treatment of scoliosis.

Surgical treatment of scoliosis.


The role of phagocyte function in resistance to infection.


An appreciation of Alfred Rives Shands, Jr.


The evolution of biomechanical analysis in the management of congenital clubfoot.


A tribute to Alfred R. Shands, Jr., orthopaedic surgeon, scholarly individual, teacher and orthopaedic surgical historian of repute, and unprecedented.


Cell population kinetics of bone growth: the first ten years of autoradiographic studies with tritiated thymidine.


Osteogenesis by radioisotope labelled cell populations in implants of bone matrix under the influence of ionizing radiation.


Calcium and skeletal tissue physiology in teleost fishes.


Biography of Alfred Rives Shands, Jr., M.D.


Intervertebral disc prolapse: a review of morphologic and biochemic knowledge concerning the nature of prolapse.


Most significant publications of Alfred R. Shands, Jr., M.D.


Fracture healing and the allograft reaction.


Responsibility and research in orthopaedic surgery.


Dog bites: prevention and treatment. Comments from the surgeon's viewpoint.


Human pituitary gonadotropin in the treatment of female sterility. A clinical trial of a Danish preparation from human pituitary glands.


Mark Berke. 1971 recipient of the American Hospital Association's.


Project 'Helping Hand'.

Project 'Helping Hand'.


A simple hemolytic plaque technique for the enumeration of anti-hapten antibody forming cells.


On the presentation of the Friedenwald award in ophthalmology to Dr. Claes H. Dohlman.


Ultramicroscopic changes in the corneal graft stroma during early rejection.


Creation of vesicoureteral reflux in the canine experimental model.


The bipolar functional dissociation of the renal tubular cells (BFD syndrome).


Vesicoureteral reflux in children. Frequency and associated urologic abnormalities.


The diffusion of selected sulfonamides, trimethoprim, and diaveridine into prostatic fluid of dogs.


Marcello Malpighi (1628-1694) and Lorenzo Bellini (1643-1704).


Complete removal of three vertebrae for giant-cell tumour.


Total spondylectomy in chondrosarcoma arising from the seventh thoracic vertebra.


Technical aspects of cardiac transplantation in the pig.


Marrow grafts between canine siblings matched by serotyping and mixed leukocyte culture. Marrow grafts were carried out between 16 canine sibling donor-recipient pairs. The pairs were matched by serological histocompatibility testing and were nonreactive in a one-way mixed leukocyte culture. Recipients were prepared for transplantation by 1500-1580 R of total body irradiation. Donor marrow was infused within 4 hr of irradiation. Recipients were not given immunosuppressive drug therapy after grafting. All 16 recipients showed evidence of prompt and sustained allogeneic marrow engraftment. Six died between 30 and 128 days after grafting with graft-versus-host disease, and three died between days 72 and 230 with pneumonia but no evidence of graft-versus-host disease with the exception of lymphoid atrophy. Seven recipients survived without graft-versus-host disease and are in excellent health between 200 and 684 after grafting. In summary, fatal graft-versus-host disease was observed in a number of canine recipients despite matching with their sibling donor by serological histocompatibility testing and by mixed leukocyte culture in a manner similar to that employed to define human HL-A matched sibling pairs. The graft-versus-host disease in these matched siblings developed more slowly than that observed in mismatched dogs, but the ultimate death of approximately half of the matched recipients emphasizes the need for posttransplantation immunosuppression even in this "compatible" situation.


Effects of E. coli septic shock on pulmonary hemodynamics and capillary permeability.


Surgical treatment of echinococcal cyst of the heart. Report of a case and review of the world literature.


Ischemic tolerance of the lung. The effect of ventilation and inflation.


Liposarcoma of the mediastinum. Case report and review of the literature.


Shattuck lecture--the anatomy of our melancholy.


Pharmacologic control of thromboembolic complications of cardiac-valve replacement.


Ferritin: structure, synthesis and function.


Liver disease associated with secondary syphilis.


Muddy river and Boylston's 250th.

Muddy river and Boylston's 250th.


Richard Cannon Eley, 1901-1971.

Richard Cannon Eley, 1901-1971.


Presidential messages. The first 50 years.


Numerical analysis of indicator concentration curves.


Cephalexin monohydrate in the treatment of urinary tract infections and urethritis.


Francois Rabelais, renaissance physician.


The ABO blood groups and cancer.

The ABO blood groups and cancer.


Successful pre-Listerian antiseptic management of compound fracture: Crowther (1802), Larrey (1824), and Bennion (ca. 1840).


Delayed cutaneous hypersensitivity to dinitrochlorobenzene as a method of quantitating immunosuppressive therapy for organ transplantation.


Evaluation of surgical masks: the potential of resin-treated wool.


In old St. John's burying ground on Mulberry Street (John Richardson Young).


Prediction of tissue loss in human frostbite with xenon-133.


Medicare-Part B.

Medicare-Part B.


L-dopa therapy in Parkinson's disease.

L-dopa therapy in Parkinson's disease.


Morphological aspects of the hypothalamic-hypophyseal system. II. Functional morphology of pituitary microcirculation.


Morphological aspects of the hypothalamic-hypophyseal system. 3. Vascularity of the hypothalamus, with special reference to its quantitative aspects.


Renal tubular dysfunction and hypergammaglobulinaemia. Electrolyte balance, electron microscopic and immunohistochemical studies.


Light- and electron-microscopic studies of the pancreatic islet cells in the chicken under normal and experimental conditions.


Late renal trnsplant failure due to the hemolytic-uremic syndrome.


Infection complicating renal homotransplantation: a prospective study.


Electroencephalographic findings in hematologic disorders.


Profile of a physician and gentleman.

Profile of a physician and gentleman.


Walter Benedict Frommeyer, Jr., an uncommon man.


The attributes of leadership.

The attributes of leadership.


Pepsin output from the damaged canine Heidenhain pouch.


Effect of metoclopramide on gastrointestinal motility in man. A manometric study.


"Clothesline" calculus after suprapubic prostatectomy: a case report.


Management of scalp defects.

Management of scalp defects.


Stereotaxic localization of extracranial foreign bodies in the head.


Immobilization and localization of DNA in cesium chloride gradients with polyacrylamide gels.


Thomas Cecil Gray, M.D.

Thomas Cecil Gray, M.D.


Dr. Donald A. Warren.

Dr. Donald A. Warren.


Hypernatremia. Complication of renal homotransplantation.


Clinical experiences with Ketalar.

Clinical experiences with Ketalar.


Regulation of xanthine dehydrogenase levels in liver and pancreas of the chick.


Evaluation of CL-1848C: a new dissociative anesthetic in normal human volunteers.


Conformations of cyclic and cylindrical peptides.


Total spinal anesthesia following lumbar paravertebral block: a potentially lethal complication.


Problems in anesthetic and airway management with Gardner's syndrome--report of a case.


Harry Daly, C.M.G., M.B., Ch.M., F.R.A.C.P., F.F.A.(R.C.S.), F.F.A.(R.A.C.S.).


Anesthetic and paraoperative management of sheep for total heart replacement.


Partial enzymic digestion of 50S ribosomal subunits from Escherichia coli.


Induction of enzymes involed in the catabolism of deoxyribonucleosides and ribonucleosides in Escherichia coli K 12.


Turnover of the deoxyribonucleoside triphosphates in Escherichia coli 15 T during thymine starvation.


Life span in Drosophila.

Life span in Drosophila.


Chemical interference with aging.

Chemical interference with aging.


The treatment of gastroschisis.

The treatment of gastroschisis.


Of bookplates, books, and their owners.

Of bookplates, books, and their owners.


Nephrotic syndrome and renal failure in a child. Résumé of case.


Sir Charles Ernest Hercus.

Sir Charles Ernest Hercus.


John Theodore Murray.

John Theodore Murray.


Pancreatic radionuclide imaging using electronic subtraction technique.


James Allen Meadows, Sr., M.D. 1884-1970.


Reticulum-cell sarcoma treated by radiation.


Howard J. West, M.D. 1931-1971.

Howard J. West, M.D. 1931-1971.


Medical collections at the American Antiquarian Society.


Quantitative assessment of cellular and humoral responses to skin and tumor allografts.


Passive immunological enhancement of skin allografts in rats.


Isoantigens common to erythrocytes and other tissue cells in the rabbit.


Mechanisms of immunological injury during antibody-mediated hyperacute rejection of renal heterografts.


The correlation of mixed leukocyte culture responses with kidney allograft survival.


Immunogenetic analysis of Ag-B histocompatibility antigens in rats.


Allotransplantation of the lung in beagle and mongrel dogs prospectively typed for lymphocytic antigens.


Prevention of corneal homograft rejection by estrogens.


Kayser-Fleischer ring. A pathological study.


On the contributions of psychoanalysis to psychiatry: mechanism and meaning.


Traumatic ischaemia in a haemophiliac. Report of a case of prolonged haemostasis with cryoprecipitate during decompression and skin grafting.


In memoriam. Robert Ingleton Stirling, 1896-1970.


The surgical treatment of male pattern baldness with punch scalp autografts.


The compleat challenger--Dr. Harry S. N. Greene.


Paradoxical increase in dark-adaptation time after vitamin A intake.


Charge your usual and customary, or reasonable, fees.


Harry S. N. Greene, M.D.

Harry S. N. Greene, M.D.


Relationship between the hospital milieu and the response to phenothiazines in the treatment of schizophrenics.


Harry S.N. Greene, M.D.

Harry S.N. Greene, M.D.


Recognition of osteodystrophy in chronic uremia.


Hemodynamic and functional mechanisms in two renal hypertensions: arterial and pyelonephritis.


A phase and electron microscopic study of vasculogenesis and erythropoiesis in the yolk sac of the mouse.


Reissner's membrane in the human cochlea.


Prevention of skin slough after radical mastectomy by the use of a vital dye to delineate devascularized skin.


Abdominal aortic aneurysms: special problems.


Anesthesia for the asthmatic patient.

Anesthesia for the asthmatic patient.


José E. Usubiaga, M.D.

José E. Usubiaga, M.D.


A comparison of the sedative and cardiorespiratory effects of diazepam and pentazocine for premedication.


Historical note: the first succesfu removal of a mediastinal mass.


Humoral antibody in canine cardiac allograft rejection.


Rat heart allograft survival with donor pretreatment.


Capuride versus methyprylon and placebo in treating sleeplessness due to presurgical anxiety.


Effects of a hyperosmotic perfusate on extended preservation of the heart.


Hemodynamic effects of volume loading in dogs following cardiac homotransplantation.


The Bainbridge reflex in canine cardiac autotransplants.


The Bier block for intravenous regional anesthesia: technic and literature review.


Double-outlet right ventricle without pulmonic stenosis. Surgical considerations and results of operation.


Repair of mitral incompetence secondary to ruptured chordae tendineae.


Radioisotopic angiocardiography. Wide scope of applicability in diagnosis and evaluation of therapy in diseases of the heart and great vessels.


Effect of volume expansion on the anginal threshold.


Hemodynamics of uremic anemia.

Hemodynamics of uremic anemia.


Uptake and removal of dimethyl sulfoxide in rabbit and human corneas during cryopreservation.


Structural changes and impairment of function associated with freezing and thawing in muscle, nerve, and leucocytes.


The ultrastructure of small bowel epithelium during freezing.


A review of research on the preservation of hearts in the frozen state.


An experimental evaluation of skin graft preservation with silicone fluid.


Studies on methyl-deficient methionine transfer ribonucleic acid from Escherichia coli.


Regulation of L-cysteine biosynthesis in Salmonella typhimurium. I. Effects of growth of varying sulfur sources and O-acetyl-L-serine on gene expression.


Cystathionine gamma-synthase from Salmonella. Spectral changes in the presence of substrates.


Early stages in complementary synthesis directed by synthetic single stranded polydeosyribonucleotide templates and catalyzed by calf thymus deoxyribonucleic acid polymerase.


Basic amino acid transport in Escherichia coli.


Volatile fatty acid tolerance and effect of glucose and VFA on plasma insulin levels in ponies.


Indwelling intravenous polyethylene catheters. Factors influencing the risk of microbial colonization and sepsis.


Orofacial dyskinesia. A dental dimension.


Therapy and prognosis of two different forms of organ involvement in cases of malignant lymphoma (Hodgkin's disease, reticulum cell sarcoma, lymphosarcoma) as well as a report about stage division in these diseases.


Role of glucose in arginine-induced insulin release in man.


Carcinoma of the oral cavity. Evaluation and management.


Gastrointestinal complications related to human renal homotransplantation.


Controlled clinical trial of 1-(2'-methyl-2'-dimethyl amino-ethyl)-3-phenyl indole HCl (A28A) in rheumatoid arthritis compared with indomethacin (Confortid).


Distribution volumes of labelled red blood cells and labelled protein and "F cells" in intact and splenectomized HbA and HbB type sheep.


Encephalopathy in toxicity tests on laboratory animals.


The gift of the college fountain.

The gift of the college fountain.


The histological establishment of the diagnosis in suspected malignancy.


Immunity in cancer.

Immunity in cancer.


Preparation of the porcine liver for allotransplantation.


Equine influenza immunisation--the role of nasal antibody--a review.


Factors influencing the incidence of postoperative abdominal adhesions: an experimental study. Adult male Wistar rats were anesthetized with intraperitoneal sodium pentobarbitone, and laparotomies were performed to determine the role of common surgical practices in the etiology of intestinal adhesions.  Rats were divided into 4 groups (Group 1, control; Group 2, small intestine delivered from the abdomen and placed on the skin without protection; Group 3, small intestine kept moist by covering with saline-soaked gauze; and Group 4, small intestine placed in plastic bag).  At the end of 1 hour, all intestine were replaced in the peritoneal cavity, and rats were sacrificed 1 week later and examined for peritoneal adhesion formaiton.  In general, the incidence of fibrinous adhesions was increased by removing the intestines from the peritoneal cavity.  Groups 3 and 4 showed no lessening of adhesion formation with their various treatments.  Incidence of plastic adhesions in laparotomy wounds closed without suturing was lower than when sutures were used.  No difference was noted among types of suture material.  The phenomenon of suture-induced adhestions seems a result of a reduction of fibrinolysin activity of serosa cells at the site, and the presence of the suture material allows the adhesion a harbor to establish itself in.


Management practices and helminthosis in the lamb.


Pasture bloat in cattle.

Pasture bloat in cattle.


Changes in animal disease patterns in the Riverina of New South Wales.


Site of energy coupling in the carrier mechanism for beta-galactoside transport.


Nature of the complementary strands synthesized in vitro upon the single-stranded circular DNA of bacteriophage phiX174 after ultraviolet irradiation. This paper describes experiments intended to decide whether UV lesions in DNA act as absolute blocks to chain elongation by the Escherichia coli DNA polymerase or only slow down the polymerization process. Ultraviolet (UV)-irradiated, single-stranded (SS) circular DNA of bacteriophage øX174 was used as template for the polymerase in a reaction mixture in vitro, under conditions allowing synthesis of not more than one complementary strand per template molecule. The mean length of the newly synthesized complementary strands (as determined by velocity sedimentation in alkaline CsCl gradients), as well as the over-all template activity (as measured by deoxyadenosine monophosphate [dAMP] incorporation) was found to decrease with the number of biologically lethal hits sustained by the irradiated templates. With the increase of time or temperature of reaction, the net synthesis of complementary strands increased (as a consequence of increased initiation), but their mean length remained constant. The mean length of synthesized strands was greater than would be expected if all biologically lethal hits were to block the polymerization process. The lethal hits which serve as blocking lesions are inferred to be pyrimidine dimers because it is possible to obtain synthesis of full-length complementary strands if, when heat-denatured, UV-irradiated, double-stranded replicative form (RF II) DNA of bacteriophage øX174 is used as a template, it is pretreated with yeast photoreactivating enzyme (YPRE) in presence of visible light.


Effects of phloretin and synthetic estrogens on beta-galactoside transport in Escherichia coli.


The prostaglandins (review of the literature).


Physicochemical and light scattering studies on ribosome particles. The light scattering technique has been used to measure the molecular weight of Escherichia coli ribosomes. The 30S, 50S, and 70S components have been isolated and purified. The refractive index increment dn/dc was found to have the same value, (0.20 +/-0.01) cm(3)/g, for the three species. The molecular weights are (1.0 +/-0.1).10(6), (1.7 +/-0.1).10(6), and (2.9 +/-0.3).10(6) daltons respectively. Some information about the dimensions in solution (radius of gyration) and the interaction constant (second virial coefficient) have been obtained, and their significance is discussed.


Insulin and heart failure.

Insulin and heart failure.


Selecting the next neuroradiological investigation with the help of a computer.


Effect of changes in ventricular activation on cardiac haemodynamics in man. Comparison of right ventricular, left ventricular, and simultaneous pacing of both ventricles.


Role of penetrating grafts in herpetic keratitis.


Striation (longitudinal mucosal folds) in the upper urinary tract. 3. Urinary tract striation in children: some experimental observations.


Management of renal failure.

Management of renal failure.


Wellington and the placebo.

Wellington and the placebo.


The Robert W. Kleemeier Award.

The Robert W. Kleemeier Award.


Clinical experience with glybenclamide in 100 non-ketotic diabetics.


Troxonium tosylate in the treatment of drug-induced extrapyramidal manifestations.


Diviminol (Z 424): a pilot study for prolonged clinical use.


A clinical study of diviminol on prolonged administration.


L-dopa and amantadine hydrochloride in Parkinson's disease.


Carbenicillin in the treatment of the critically ill patient.


Lead I electrocardiographic screening by special purpose computer.


Anti nuclear factors in systemic lupus erythematosus.


The vectorcardiogram in complete transposition of the great arteries: correlation with anatomic and hemodynamic findings and calculated left ventricular mass.


The rabbit zygote: formation of annulate lamellae.


Frozen-fractured images of blood capillaries in heart tissue.


A new preparation method for dark-field electron microscopy of biomacromolecules.


A comparative study of freeze-etch replicas and thin sections of rat liver.


A detailed ultrastructural study of the head membranes of ejaculated bovine sperm.


Penetration of the oocyte envelope by spermatozoa in the spider crab.


Resumption of female reproductive function following renal transplantation.


Parenthood in renal homograft recipients.


Gametocytemia in falciparum malaria.

Gametocytemia in falciparum malaria.


The diagnostic microbiology of lung biopsy: correlation with viral serology.


Mechanism for prolonged survival of pig renal allografts.


Establishment of lymphoid cell lines in patients with common viral diseases.


Some techniques in corneal grafting.

Some techniques in corneal grafting.


The treatment of open- and narrow-angle glaucoma.


Donor-host cross circulation before skin homograft in the rat.


In vitro sensitization to transplantation antigens. I. Sensitization of lymphoid cells by allogeneic macrophages.


Ultrasonic studies for the early detection of acute cardiac rejection.


Histocompatibility genes of mice. XI. Evidence establishing a new histocompatibility locus, H-12, and new H-2 allele, H-2bc.


The effects of phytohemagglutinin and antilymphocyte globulin in inducing immunosuppression and tolerance  in mice.


Bone marrow transplantation for aplastic anemia. Establishment of chimerism using multiple HL-A identical donors following pretreatment with cyclophosphamide.


Soluble RNA-treated autogeneic lymphocytes. Effect on canine renal allografts.


Spontaneous reticulum cell sarcomas developing in C3H-HeJ mice on prolonged immunosuppressive therapy.


Burns in children.

Burns in children.


Radiology of the thoracic duct.

Radiology of the thoracic duct.


James Allen Meadows, Sr., M.D. 1884-1970.


Direct attachment of orthodontic brackets to dental enamel. A preliminary clinical report.


Scientia with a touch of ars.

Scientia with a touch of ars.


The autoxidation of red cells.

The autoxidation of red cells.


Epsilon-Aminocaproic acid therapy for dental extractions in haemophilia and Christmas disease: a double blind controlled trial.


Systemic aspergillus infection: report of a fatal case nine months after renal homograft transplantation.


Continuous measurement of urine loss and frequency in incontinent patients. Preliminary report.


Closed injuries to the duodenum.

Closed injuries to the duodenum.


Controlled trial of phetharbital, a non-hypnotic barbiturate, in unconugated hyperbilirubinaemia. Eleven patients with mild unconjugated hyperbilirubinaemia (Gilbert's syndrome) took part in a double-blind cross-over trial of phenobarbitone and phetharbital, a non-hypnotic barbiturate. Significant reductions in plasma bilirubin were observed with both drugs, but six patients complained of sleepiness on phenobarbitone, and phetharbital was preferred by most patients. Phetharbital was also effective in the rare severe unconjugated hyperbilirubinaemia of the Crigler-Najjar syndrome (Type 2). Symptoms attributed to Gilbert's syndrome, including nausea and abdominal pain, were less consistently relieved.


Thermodilution measurement of left and right ventricular outputs.


A new beating heart preparation. Ultrastructural studies with special reference to vesiculation of intercalated discs.


Mechanism of lithium carbonate in manic-depressive illness (a review).


The dyskenesias: a new therapeutic approach.


Complications of anti-rabies treatment.

Complications of anti-rabies treatment.


The fine structure of "non-specific" grey matter (laminae V and VII) in the cat spinal cord.


The role of immunosuppression in the genesis and growth of malignant tumours.


Immunosuppressive action of L-asparaginase.


Xenogenic heart transplantation in a closely related species system, fox-dog.


Related donor renal allografts in hereditary nephritis Report of two siblings.


The mechanism of replication of phi X174 single-stranded DNA. II. The role of viral proteins.


The mechanism of replication of phi X174 single-stranded DNA. 3. An enzymic study of the structure of the replicative form II DNA.


DNA synthesis in Escherichia coli in the presence of cyanide.


Compatibility between two F' factors in an Escherichia coli strain bearing a chromosomal mutation affecting DNA synthesis.


Persistence of small fragments of newly synthesized DNA in bacteria following thymidine starvation.


On the origin of replication of Escherichia coli chromosome.


An analysis of the pyrogen-induced inhibition of gastric motility in sheep.


The measurement of stroke output and stroke work of the right and left heart in relation to changes in filling pressure in some forms of heart failure in man.


The measurement of blood flow by indicator-dilution methods.


Electrical measurement of pulmonary oedema with a focusing conductivity bridge.


The Society for the Study of Fertility, 1950-71.


Determination of cardiac output in the anaesthetized rat.


A review of audiometry.

A review of audiometry.


Medazepam: a new tranquillizer.

Medazepam: a new tranquillizer.


An ancient practice alive and well today. The story of Westgate End House.


Immunofluorescent and morphological studies in congenital nephrotic syndrome.


In vitro methods for the study of the adenohypophysial functions to secrete gonadotrophin.


Hyposensitization in house dust allergy asthma. A double-blind controlled study with evaluation of the effect on bronchial sensitivity to house dust.


Morphological and immunohistochemical findings in small intestinal biopsy in children with IgA deficiency.


Ioglycamide (Bilivistan) as a contrast medium for intravenous cholegraphy. A clinical and experimental investigation.


Evolution and revolution in anaesthetic training.


In memoriam.

In memoriam.


Effect of cold perfusion on the function of auto-transplanted kidneys.


Surgery of endometrial cancer in the Bonney tradition.


Inhibition by kasugamycin of initiation complex formation on 30S ribosomes.


Ribonucleoside diphosphate reductase from Escherichia coli: a new approach to the problem of stereospecificity.


Some salient features of the one hundred years nucleic acid research.


Enzymatic properties of bacteriophage T4 altered and modified RNA polymerase as compared to DNA-dependent RNA polymerase from E. Coli (EC 2.7.7.6).


Cool:nursing--cool:television or McLuhanism applied.


Raphael R. Goldenberg, 1904-1970.

Raphael R. Goldenberg, 1904-1970.


Repair and reconstruction of the anterior cruciate ligament in dogs. Factors influencing long-term results.


Studies of proliferative capabilities in isolated epidermal basal and differentiated cells.


The delto-pectoral flap and composite resection.


On the toxicity of our environment.

On the toxicity of our environment.


Effect of pyloric ligation on the gastric secretion of dissolved mucins in fasting rats.


A conspectus of research on amino acid requirements of man.


Calling the odds for the cancer sweepstakes.


Report debated at last.

Report debated at last.


Nixon may sell out to Kennedy on NIH.

Nixon may sell out to Kennedy on NIH.


Water and industry.

Water and industry.


Sex determination in birds and mammals.

Sex determination in birds and mammals.


Mercury in a coastal marine environment.


Role of electrical repulsive forces in synovial fluid.


Differences in growth in vitro of adipose cells from normal and obese patients.


Conformation of synthetic polypeptide monolayers.


Inhibition of carcinogenesis by dietary zinc.


Multiple sex chromosomes in a Mexican cyprinodontid fish.


Enzyme variants as markers in the study of pre-copulatory isolating mechanisms.


Antagonistic effects of alpha and beta-adrenergically coded hypothalamic neurones on consummatory behaviour in the rat.


Increased fertility in males with the sickle cell trait?


Energetical structure of zoological systems.


Insect visual pigment sensitive to ultraviolet light.


New nitrogenase model for reduction of molecular nitrogen in protonic media.


Cycles in social behaviour.

Cycles in social behaviour.


Is the haptic Müller-Lyer a visual phenomenon?


Visual system anomaly associated with albinism in the cat.


Transduction and skeletal evolution.

Transduction and skeletal evolution.


Effect of PCB on nocturnal activity in caged robins, Erithacus rubecula L.


Skua numbers and conservation problems at Cape Hallett, Antarctica.


Antlers--the unbrittle bones of contention.


Right and left handed reading of Braille.


Sickle cell research.

Sickle cell research.


The rheumatism department at the West London hospital.


Reconstruction of the severely mutilated hand.


Freud in the American scene.

Freud in the American scene.


Comparison of oral prednisolone and intramuscular methylprednisolone in classical rheumatoid arthritis in out-patients.


A controlled clinical study of a new antidepressant (trazodone).


A comparison between the hemagglutination test with formalin treated erythrocytes and the immunofluorescence test with worm particles, for schistosomiasis.


Superior mesenteric artery occlusion. A review and case report.


Review of the origin and kinetics of the promonocytes, monocytes, and macrophages and a brief discussion of the mononuclear phagocyte system.


Effect of lumbar sympathectomy on muscle blood flow in advanced occlusive vascular disease.


Cellular immunity.

Cellular immunity.


Direct immunofluorescent studies of pemphigus and bullous pemphigoid.


Syphilis in the Bible.

Syphilis in the Bible.


Vitamin C.

Vitamin C.


Yaws.

Yaws.


Incidental prophylactic inferior vena cava clipping.


Endotoxin shock in the subhuman primate. II. Some effects of methylprednisolone administration.


Xylose and inulin absorption. From the small intestine of dogs following endotoxin shock.


Alimentary circulation in the pup during the postnatal period.


Experimental Noble operation performed with use of tissue adhesive.


Histocompatibility in survival of hepatic transplantations.


Escherichia coli in newborn lambs.

Escherichia coli in newborn lambs.


Bovine salmonellosis in England and Wales.


Nature of phenotypic masking exhibited by drug-dependent streptomycin A mutants of Escherichia coli.


Drug dependence reversed by a ribosomal ambiguity mutation, ram, in Escherichia coli.


Defective ribosomes in chloramphenicol-treated Escherichia coli.


Mechanism of action of rat liver DNA methylase. I. Interaction with double-stranded methyl-acceptor DNA.


Characterization and synthesis of phi X174 proteins in ultraviolet-irradiated and unirradiated cells.


Nucleotide sequence analysis of DNA. II. Complete nucleotide sequence of the cohesive ends of bacteriophage lambda DNA.


Doctor J.S. Collings.

Doctor J.S. Collings.


Observations on obesity.

Observations on obesity.


Experience with an insecticide-drug combination and observations on suppressive chloroquine-pyrimethamine treatment.


Characterization of a drug resistant strain of Plasmodium falciparum from the Philippines.


Are we building too many medical schools?


Adsorption of benzalkonium chloride onto different filter media during bacteriological filtration.


Arterial injuries and their management.

Arterial injuries and their management.


The Raynaud syndrome.

The Raynaud syndrome.


Deep vein thrombosis.

Deep vein thrombosis.


Physiological measures of sexual arousal in the human.


Auto-immune hyperlipidemia. An atherogenic metabolic disease of immune origin.


Prolongation of skin graft survival in mice by pretreatment with H-2 antigen and cyclophosphamide.


Sexual frequency and contraceptive pills.


Writing.

Writing.


The new President of the R.C.V.S.

The new President of the R.C.V.S.


Mechanism of the antipeptic action of anionic carbohydrate and its clinical application for the treatment of peptic ulcer.


Studies on the luteinizing hormone secretion from cultured cells of the porcine pituitary.


Autoradiographic and ultrastructural observations on the frog's olfactory mucosa.


Office bacteriology.

Office bacteriology.


The haunting influence of Alexander Graham Bell.


Non-white deaf persons: educational, psychological, and occupational considerations. A review of the literature.


Aggressive treatment of septic abortion.


Treatment of Bartholin cysts.

Treatment of Bartholin cysts.


Osler: "diagnose" or "diagnosticate"?

Osler: "diagnose" or "diagnosticate"?


Degradation products and the role of coagulation in "persistent" glomerulonephritis.


Articular manifestations of systemic lupus erythematosus.


Chronic mucocutaneous candidiasis: model-building in cellular immunity.


Did Beethoven have Paget's disease of bone?


Effect of histidine on the enzyme which catalyzes the first step of histidine biosynthesis in Salmonella typhimurium.


Structural properties of 5-fluorouracil-containing transfer ribonucleic acids from Escherichia coli.


Analysis of transcription in vitro using purine nucleotide analogs.


Implication of tyrosine in iron binding in hemerythrin.


Studies on specificity and binding properties of the blood group A reactive hemagglutinin from Helix pomatia.


Homoserine dehydrogenase-aspartokinase of Escherichia coli. Comparison of threonine saturation and enzyme conformation.


Protein biosynthesis on chick oviduct polyribosomes. I. Changes during estrogen-mediated tissue differentiation.


Molecular weighr of Escherichia coli glutaminyl transfer ribonucleic acid synthetase, and isolation of its complex with glutamine transfer ribonucleic acid.


Comparison of ultrafiltration systems for concentration of biologicals.


An analysis of the rapidly synthesized ribonucleic acid of the normal human lymphocyte by agarose-polyacrylamide gel electrophoresis.


Surgical aspects of acute renal failure.


A comparative trial of fenfluramine and diethylpropion in obese, hypertensive patients.


Surgical aspects of chronic renal failure.


Anaemia in renal failure.

Anaemia in renal failure.


Renal failure in the tropics.

Renal failure in the tropics.


Antiobiotics in renal failure.

Antiobiotics in renal failure.


Radiology in the diagnosis of renal failure.


Dietary treatment of chronic renal failure.


Peritoneal dialysis.

Peritoneal dialysis.


Intermittent haemodialysis in the home.

Intermittent haemodialysis in the home.


Maintenance haemodialysis in hospital.

Maintenance haemodialysis in hospital.


The present status of renal transplantation.


Management of the acute uraemic emergency.


Tendon lacerations of the hand. (Case P41).


Studies on erythropoiesis in uremic and post-transplant (renal) patients utilizing radioactive iron and chromium. The association of anemia with chronic renal disease is well known. The striking hematologic improvement following a successful renal allotransplantation led to the present study. Using radioactive (59)Fe, ferrokinetic measurements were carried out in nine uremic patients (seven with and two without anemia), four post-allotransplant cases, three patients with iron deficiency anemia and a group of five normal subjects. Erythrocyte life-span was calculated by (51)Cr-labelled, autotransfused red cells in all patients who had had transplants and in three patients with renal anemia. The results showed that in patients with renal anemia the plasma radioiron clearance was slightly delayed but the (59)Fe incorporation into the circulating erythrocytes was significantly decreased. Red cell life-span was moderately shortened in two out of three uremic patients investigated. The findings constitute evidence of ineffective erythropoiesis in patients with renal anemia. By comparison, the four transplant patients showed normal (59)Fe plasma clearance and red cell incorporation; the (51)Cr erythrocyte survival was normal in all four patients.


Peter Mere Latham (1789-1875): a great medical educator.


Plasma calcitonin in renal osteodystrophy. Whether calcitonin plays a significant role in the pathogenesis of renal osteodystrophy is not known. Plasma calcitonin-like activity (CLA) was measured by means of an extraction procedure and bioassay in 17 patients with chronic renal failure. Recent bone biopsy data were available for 11 patients. Plasma CLA was found to be in the normal range in the patients studied. There was a positive and strong correlation between plasma calcium and plasma CLA. Chronic dialysis and renal transplantation had no significant effect on plasma CLA. The severity and type of bone lesions did not correlate with plasma CLA. Although plasma calcitonin in chronic renal failure does not appear to be directly related to renal osteodystrophy, normal mobilization of calcitonin may protect the skeleton to some degree from the high levels of parathyroid hormone usually present in such patients.


Induction of overt diabetes in KK mice by dietary means.


A theoretical approach to the regulatory mechanism in the brain-hypophyseal-gonadal system with reference to its mathematical modeling and computer simulation.


An apparently unique anatomical illustration in an early rabbinical book.


Rat intratesticular test systems for investigating luteinizing hormone releasing factor (LRF) and luteinizing hormone (LH) activities: effects of rat stalk-median eminence extract and internal environment of rat testis upon rat and quail anterior pituitaries.


A study of congenital malformations of the central nervous system among Glasgow births 1964-1968.


Diabetes mellitus--present problems and new research. VII. Retinoplathy.


Florence Hazel Smith, 1887-1971.

Florence Hazel Smith, 1887-1971.


Transthoracic electrical impedance variations associated with respiration.


Use of a new cardiac output computer for human hemodynamic studies.


Prolonged survival after kidney transplantation without the use of corticosteroids.


Paraventricular-hypophysial neurosecretory pathways in the guinea-pig.


Effects of hypothalamic implants of gonadal steroids on courtship behaviour in Barbary doves (Streptopelia risoria).


Influence of insulin injected into the lateral ventricle on pituitary growth-hormone release in the rat.


The radioisotopic estimation of regional blood flow, blood volume, and hematocrit in the dog lung.


Large dose errors due to redistribution of 133-Xe in carpules and plastic syringes.


Pulmonary and systemic blood pressure responses to large doses of albumin microspheres.


Rapid double-isotope dilution derivative assay of plasma testosterone.


Routine liquid scintillation counting technique for plasma 59Fe.


Radiochromate RBC survival kinetics in the normal human adult.


Nuclear pioneer lecturer--1971. Charles L. Dunham, M.D.


Distinguished nuclear pioneer--1971. Glenn Theodore Seaborg, Ph.D.


Disappearing malaria: some reflections.

Disappearing malaria: some reflections.


Shigella-associated diarrhoeal disease in pre-school children.


Biochemical and immunochemical studies on cobrotoxin.


Hemorrhagic necrosis in mouse bone marrow induced by endotoxin and its relation to the hypoferremic reaction.


Phage-conversion of toxigenicity in Clostridium botulinum types C and D.


Effect of thiol-compound on toxicity of habu snake (Trimeresurus flavoviridis hallowell) venom.


Calcium-dependent histamine release with degranulation from isolated rat mast cells by adenosine 5'-triphosphate.


The effect of subtotal parathyroidectomy and renal transplantation on mineral balance and secondary hyperparathyroidism in chronic renal failure.


Fluoro-electrosyneresis for classification of human immunoglobulin class and light chain type.


Drug jars, instruments and books.

Drug jars, instruments and books.


Comparison of propranolol and LB 46 (prinodolol) on hyperthyroid tachycardia.


Local chemical regulation of the flow resistance in the bronchial tree and pulmonary circulation.


Comparative studies of the protective effect of Alupent and Th 1165a against histamine in man.


Vanished industries in Dublin.

Vanished industries in Dublin.


Hexokinase: a compartmented enzyme.

Hexokinase: a compartmented enzyme.


Treatment of group A streptococcal pharyngitis in children. Comparison of lincomycin and penicillin G given orally and benzathine penicillin G given intramuscularly.


Schizophrenia in infancy, childhood, and adolescence.


Systemic diseases having ocular manifestations including metabolic disturbances.


Tabulation of findings in the muscular dystrophies and in myotonia dystrophica.


Autoimmunity in thermal injury: occurrence of rheumatoid factors, antinuclear antibodies and antiepithelial antibodies.


Specific binding of immunoconglutinin in tissues and synovial fluids from patients with rheumatoid arthritis.


Tissue antibodies in idiopathic autoimmune haemolytic anaemia.


Rabbit antibodies reacting with brush border of rodent renal tubules.


Human antibody against rat gastric parietal cells and kidney brush border.


The study of the acid phosphatase of macrophagal lysosomes in delayed-type hypersensitivity.


Partial mechanization of membrane immunofluorescent staining techniques.


Chronic effects of nicotine on gastric secretion in vagotomized rats.


Effect of normal and irradiated marrow grafts on the haemopoietic recovery after a sublethal irradiation.


'High dose' immunologic tolerance to Escherichia coli lipopolysaccharide assessed by bacteriolytic and hemolytic plaque assays.


Studies on rII region of T2L phage.

Studies on rII region of T2L phage.


Bacterial endotoxins as immunosuppressive agents.


Recognition of bacterial initiator tRNA by an initiation factor.


'Average of normals' used as control of accuracy, and a comparison with other controls.


Screening for metabolic disorders using gas-liquid chromatography, mass spectrometry, and computer technique.


Cardiac output during positive and negative work.


Hyperacute cortical necrosis after antibody pretreatment of syngeneic rat kidney transplants.


Glomerulopathy in the transplanted kidney.


Hyperacute rejection of a kidney allograft.


Apparent success in avoiding hyperacute rejection in a renal allograft.


Careers in the Veterans Administration.

Careers in the Veterans Administration.


Histologic and volumetric investigation of bipolar stereotaxic radiofrequency heat lesions.


Simple primary closure for pilonidal disease.


On the treatment of ganglia.

On the treatment of ganglia.


Reticulosarcoma of the stomach. Report of 13 cases with follow-up results.


Determination of total body water and its turn over rate. A methodological study with tritium-labeled water.


Perforated appendicitis and antibiotics. A survey and a controlled clinical trial.


Morphologic evidence that rhe renal calyx and pelvis control ureteric activity in the rabbit.


Vasculogenesis in the chick embryo. An ultrastructural study.


Angiography in angiomas of the face.

Angiography in angiomas of the face.


The American Journal of Roentgenology, Radium Therapy and Nuclear Medicine.


An evaluation of prism prescribed by Sheard's criterion.


Differential incorporation of 5-bromodeoxyuridine into DNA puffs of larval salivary gland chromosomes in Rhynchosciara.


Synchronization of E. coli K 12 by membrane selection.


An isotopic study of DNA-dependent RNA polymerase of E. coli following T4 phage infection.


Criteria of air flow and negative pressure for high volume dental suction.


N-Acetylanthranilic acid biosynthesis in Aerobacter aerogenes and Escherichia coli.


Aristotle corrects Eudoxus.

Aristotle corrects Eudoxus.


A new interpretation of the golden horns. A comment on Professor Willy Hartner's book.


Planetary distances and sizes in an anonymous arabic treatise preserved in Bodleian Ms. Marsh 621.


Recent trends in the early treatment of cleft lip and palate.


The stimulus-secretion coupling of glucose-induced insulin release. V. The participation of a microtubular-microfilamentous system.


Properties of the DNA synthesizing activity in DNA-membrane complexes from bacterial cell extracts.


pH dependence of the activity of beta-galactosidase from Escherichia coli.


Crystallographic evidence for the tetrameric subunit structure of L-asparaginase from Escherichia coli.


A reinvestigation of the anomeric configuration of mannose in the antigens of Salmonella groups B, D and E.


Role of serum hepatitis virus in chronic liver disease.


Immunological apparatus of the gut and inflammatory bowel disease.


Measurements of gastrointestinal protein loss.


Pepsin hydrolysis of IgA--delineation of two populations of molecules.


ADPAC names Donelan as Chief Executive.

ADPAC names Donelan as Chief Executive.


In vitro induction of anti-DNP antibody by immunogenic RNA from rabbit liver.


Monarticular idiopathic septic arthritis in horses.


Inhibition of chloramphenicol O-acetyltransferase of Escherichia coli by basic triphenylmethane dyes.


Antimetabolites produced by microorganisms. 3. 2-aminopurine-6-thiol (thioguanine).


"You can never plan the future by the past". The development of child and adolescent psychiatry in England and Wales.


Normal psychosexual development.

Normal psychosexual development.


Sixty years of oto-laryngology.

Sixty years of oto-laryngology.


Histology of the forefoot and hind foot interdigital and median glands of the pronghorn.


Failure of neuraminidase to unmask histocompatibility antigens on trophoblast.


Polynucleotide ligase and phiX174 single strand synthesis.


Immunogenicity and antigenicity of lymphoid cells treated with neuraminidase.


Mechanism of milk secretion.

Mechanism of milk secretion.


Suppressor genes.

Suppressor genes.


Results of renal transplantations using living donors and histocompatibility testing.


Small DNA bacteriophages and their contributions to molecular biology.


Tuberculin activity of somatic fractions obtained from Mycobacterium.


Aerosols containing antibiotics and infectious drug resistance.


Autoimmune factors in male infertility: some new perspectives.


Some aspects of radiation effects on cell membranes.


The William Hawksworth Memorial Lecture 1970.


No man an island.

No man an island.


Biliary tract disease since antiquity.

Biliary tract disease since antiquity.


Purkyne's fibers: the first report (1839), the German version (1845), and the English version.


Clinical trials of 1-beta-D-arabinofuranosyl cytosine and 1,3-bis-(2-chloroethyl)-1-nitrosourea combination in metastatic cancer and acute leukemia.


Combination chemotherapy for 418 cases of advanced cancer.


Value of arteriography in the diagnosis of benign and malignant bone lesions.


Myelomonocytic leukemias: a historical review and perspectives.


Effects of heterologous antilymphocyte antibody on the development of spontaneous and transplanted lymphoma in AKR mice.


The role of the exocrine pancreas in the stimulation of insulin secretion by intestinal hormones. II. Insulin responses to secretin and pancreozymin in experimentally-induced pancreatic exocrine insufficiency.


The effect of 3-methyl salicylic (O-cresotinic) acid on plasma insulin and glucose tolerance in diabetic and non-diabetic subjects.


Computer assisted instruction in dental education.


Isoetharine and salbutamol--a comparative bronchodilator trial.


An appliance for the management of cheek biting.


Geographical variation in serological types of urinary Escherichia coli.


Failure of passive transfer of homograft sensitivity in mice by means of extracts of sensitised lymphoid cells.


Production of rubella antiserum in hamsters.


Mixed infective endocarditis in a heroin addict.