Case for diagnosis. Lentil pulse pneumonia.


Incidence of primary carcinoma of the ureter: a report of five cases.


Acquired atresia of the bulbous urethra in traumatic spinal cord lesion.


Aggressive management of advanced testicular malignancy: experience with 147 patients.


Gastric ulcer in the Canal Zone.

Gastric ulcer in the Canal Zone.


Behavior therapy in an army mental hygiene clinic: reconditioning of a phobia. Case report.


The importance of arterial pulse findings in diagnosing aortic arch anomaly: a case report.


The physician-patient privilege, article 31, and the military doctor.


Importance of anaerobic bacteria in chronic lower urinary tract infections in males.


Melioidosis: serologic studies on US Army personnel returning from Southeast Asia.


Case for diagnosis.

Case for diagnosis.


Glycogen storage disease of the heart (Pompe's disease): report of a case and review of diagnostic features.


Gastric carcinoma in the Canal Zone.

Gastric carcinoma in the Canal Zone.


Young nurses' reasons for joining, remaining in, and leaving the Army.


Something for the retired military physician.


Meningococcal disease outbreak at Fort Leonard Wood, Missouri.


The Navy's first coronary care unit: a follow-up report.


Case for diagnosis. Borderline tuberculoid leprosy.


Avoiding the collapse of health care delivery.


Considerations for planning and implementing a flying health service: experiences in the Ryukyu Islands.


Education at the Armed Forces Institute of Pathology.


The hard work of innovation in pharmacy.


The use of the Eighth Revision International Classification of Disease Adapted for Use in the United States for psychiatric disorders in the Navy.


Use of haloperidol to reduce LSD flashbacks.


Blepharoptosis.

Blepharoptosis.


Persistent cough--the presenting feature in unsuspected sarcoidosis: a case report.


Fixation of muscle biopsy specimens in neuromuscular diseases.


Acute renal failure complicating heatstroke: case report.


The Federal physician's attitude toward alcoholism: a sampling of Naval Medical Officers' opinions.


Diagnosis and treatment of fractures of the malar eminence.


Inhalation therapy: experience in an Army Evacuation Hospital in Vietnam.


Case for diagnosis. Osteosarcoma complicating Paget's disease of the skull.


Bilateral tension pneumothorax after pneumoperitoneum: a case report.


Otolaryngic problems of underwater exploration.


Optometry's role in the detection of pathology.


Artillery fragment in 3rd ventricle of brain producing delayed block of Iter of acqueduct of Sylvius: case report.


A comparison of patients with proven and suspected myocardial infarction admitted to a coronary care unit.


Coronary care in a remote community.

Coronary care in a remote community.


Bacterial enteropathogens in the Republic of South Vietnam.


Effects of splenectomy and splenosis on the blood and platelet count and red cell morphology.


A new method for detecting Plasmodia.

A new method for detecting Plasmodia.


How diligently should the diagnosis of sickle cell trait be pursued? Clinical case report with military implication.


Mycoplasma pneumoniae pneumonia.

Mycoplasma pneumoniae pneumonia.


Laboratory aids in the diagnosis of folic acid and vitamin B 12  deficiencies.


Minor infections of the hand in Marine recruits: an analysis of 100 consecutive cases.


Ipsilateral ureteroureterostomy.

Ipsilateral ureteroureterostomy.


Infarction of the omentum.

Infarction of the omentum.


Cryotherapy and corticosteroids in the treatment of rattlesnake bite.


Flashback phenomena in basic trainees who enter the US Air Force.


Case for diagnosis. Malignant melanoma of the ciliary body.


The patient care coordination team: an adjunct to health services.


A program for the comprehensive laboratory evaluation of Vietnam medical air evacuees to Japan.


Differentiation of myoglobin and hemoglobin in biological fluids.


Upper extremity injuries.

Upper extremity injuries.


Cardiovascular considerations of rat pulmonary edema.


A review of ninety-seven patients with acute myocardial infarction.


Evaluation of dangerous behavior of active duty servicemen.


Marijuana.

Marijuana.


Atrioventricular and intraventricular conduction disturbances accompanying arrhythmias in acute myocardial infarction.


Skin infections and acute glomerulonephritis: report of a symposium.


Chronic purulent tuberculous empyema treated by primary decortication.


Case for diagnosis. Lichen amyloidosus.

Case for diagnosis. Lichen amyloidosus.


Tangential missile wounds of the skull: a summary of the radiographic features in nineteen cases.


Penetration of the skull by teeth: a case report.


CS in water. I. Effects of massive doses sprayed into the eyes of rabbits.


Clinical evaluation of a combat restorative material: one year results.


CS in water. II. Effects on human eyes.

CS in water. II. Effects on human eyes.


CS in trioctyl phosphate: effects on human eyes.


Pyogenic liver abscess: a case report.

Pyogenic liver abscess: a case report.


The coupling of science and technology in the early development of the World War II aerosol bomb.


The national library of medicine: no finery or furbelows.


Economic, social, and political factors in health planning.


Presidential address.

Presidential address.


Personality inventories as selective and prognostic criteria.


War surgery in a forward surgical hospital in Vietnam: a continuing report.


A plug for the talent leak.

A plug for the talent leak.


War comes to the peacemaker: William Osler, 1914-1918.


A study of leukemia within the West German Armed Forces.


Does physical exercise aggravate hepatitis?


Medical support for the amphibious ready group in Vietnam.


The photofluorograph as a tuberculosis case finding tool: an evaluation.


Recurrent bacterial meningitis: immunologic observations.


Effects of gavage feeding of premature infants upon cardiorespiratory patterns.


Endocardial fibrous proliferation in a moderate size ventricular septal defect: report of a case presenting as an aneurysm of the membranous ventricular septum.


Pulsating water jet devices in debridement of combat wounds.


A psychiatric experience with Project 100,000.


Coronary artery-right atrial fistula secondary to bullet wound of the heart: report of a case with successful surgical repair.


Attitudes of dental officers on expanding the role of ancillary personnel.


An Air Force alcoholic rehabilitation program.


Using time-sharing computers in biomedical research.


An unusual case of S. japonicum-like infestation acquired in Laos.


Case for diagnosis. Protothecosis involving lymph nodes of a cow.


Hemoperitoneum: a rare complication of pancreatitis. Case report.


Young men with myocardial infarction.

Young men with myocardial infarction.


Military medical-dental community relationship projects.


Heroin-induced pulmonary edema: a case report.


Remarks of the Federal medical chiefs.

Remarks of the Federal medical chiefs.


Neisseria meningitidis within the crews of a Polaris submarine: a longitudinal carrier study.


Registry of Tissue Reactions to Drugs.

Registry of Tissue Reactions to Drugs.


Case for diagnosis. Complications of femoral neck fracture.


A practical synopsis of consumption coagulopathy.


Evaluation of undefined material present in stored blood infusion.


Erythrokinetics during treatment of acute falciparum malaria.


Toward goal-directed mental health services: a comparative analysis of ten Army programs.


Drug abuse prevention program.

Drug abuse prevention program.


A technique for percutaneous renal biopsy in infants and children.


Influence of the position of the head on the cerebrospinal fluid pressure. Variations of the Queckenstedt sign.


Composite complex odontoma with associated impaction and autogenous bone graft: case report.


The blood cell separator: the nurse's role in a new procedure for the treatment of leukopenia.


Night vision testing.

Night vision testing.


The passing of the "Old Red Brick".

The passing of the "Old Red Brick".


Carlisle Barracks Pennsylvania: some aspects of its medical history.


An evaluation of patients' satisfaction with Army medical treatment.


Patient transport board for in-hospital use.


A therapeutic proposal.

A therapeutic proposal.


Meningococcal pericarditis in the antibiotic era.


Rifampin and meningococci: the price of prophylaxis.


Drowning and near-drowning: a review of ten years' experience in a large Army hospital.


Family health education and its place in the training of student aviators: a method.


The family in cultural isolation.

The family in cultural isolation.


Marijuana as a coping device in Vietnam.


The young veteran as a psychiatric patient in three eras of conflict.


Implication of physical conditioning in reducing the impact of blood loss.


Platelet enlargement in malaria.

Platelet enlargement in malaria.


Current status of intestinal parasitism in the Ryukyu Islands.


Advanced neurosurgical care for combat casualties in the United States Navy: a critique.


Selection of patients for carotid artery reconstruction.


Radioisotope renography improved by sequential renal scintiphotography.


Parotid gland tumors.

Parotid gland tumors.


Single subject films--a new concept in continuing education.


Intraperitoneal contraceptive device removal via colpotomy.


Case for diagnosis. Juvenile aponeurotic fibroma.


An historical event at the Armed Forces Institute of Pathology.


Military gastritis.

Military gastritis.


The cortical connections of the nucleus pulvinaris of the dorsal thalamus in the Rhesus monkey.


Spontaneous unit activity in the ventrolateral thalamus of the chronic monkey.


A re-evaluation of the "nucleus ventralis lateralis" and its cerebellar connections. A study in man and chimpanzee.


Activity of thalamic and cortical neurons in relation to learned movement in the monkey.


Early esotropia.

Early esotropia.


The role of the thalamus in the regulation of aggressive behavior.


Functional morphology of the specialized tissues of the heart. (With plates 1-3).


Effect of antihistamine on early transient incapacitation of monkeys subjected to 4000 rads of mixed gamma-neutron radiation.


Monkey performance after partial body irradiation.


Diagnosis of iron storage disease with desferrioxamine (Desferal test).


Tolerance to phenindione of patients with different thromboembolic disorders.


A modification of the Hicks and Pitney test for the distinction between haemophilia A and Christmas disease.


Studies of basophils. Basophilic leukocytes and gonodal activity in the rabbit.


Alpha-2-macroglobulin and selectivity of protein excretion.


Molecular pathology of ceruloplasmin.

Molecular pathology of ceruloplasmin.


The occipital lobe as integrator of four visual input systems and three regulating output systems.


The propagation of focal cortical epilepsies and its modes.


Caloric requirements after operation.

Caloric requirements after operation.


Miscellaneous gastric lesions.

Miscellaneous gastric lesions.


Treatment of various types of asthma with disodium cromoglycate (intal): a two year appraisal.


Ultrastructural patterns of bacterial breakdown in normal and granulomatous rabbit alveolar macrophages.


Desmosine and isodesmosine levels of aortic elastin in control and pyridoxine-deficient monkeys.


Hyperacute experimental allergic neuritis.


Bromobenzene-induced hepatic necrosis: species differences and protection by SKF 525-A.


Enhancement of catalase activity in subcellular fractions of Tetrahymena pyriformis following addition of purified C-reactive protein.


Ultrastructural changes in the anterior pituitary gland after the administration of synthetic TRH.


Lymphocyte and plasma cell neoplasms associated with autoimmune diseases.


Mitosis.

Mitosis.


Salmonid viruses: infectious pancreatic necrosis virus. Morphology, pathology and serology of first European isolations.


Some biological and immunizing properties of a high-titered freeze-dried EDTA-released rubella virus hemagglutinin containing live virus.


Mutual obligations.

Mutual obligations.


Clinical application of synthetic thyrotropin releasing hormone to TSH secretion test (TRH-test).


Glibenclamide therapy in diabetes mellitus. In an initial trial of glibenclamide in the treatment of maturity onset diabetes mellitus 28 patients were treated for up to one year and no toxic effects or side-effects were encountered. The hypoglycaemic potency of this drug is such that 5 mg. of glibenclamide corresponds to about 1,500 mg. of tolbutamide and 375 mg. of chlorpropamide.


The aspiny neurons and the glia in the primate striatum: a golgi and electron microscopic study.


Protection by various steroids against gold nephropathy.


Observations on the oligodendroglia in the primate striatum. Are they Ramón y Cajal's "dwarf" or "neurogliaform" neurons?


Further observations on the spiny neurons and synaptic endings in the striatum of the monkey (Saimiri sciureus).


On the specificity of anti-denatured-DNA, anti-poly-I anti-poly-I:C antibodies.


Enzyme changes in malnutrition.

Enzyme changes in malnutrition.


Enzyme kinetics.

Enzyme kinetics.


Enzyme assays in the management of pregnancy.


Population genetic studies in Australian Aborigines of the Northern Territory. Blood group genetic studies on populations sampled at 16 localities including Arnhem Land and Groote Eylandt.


Studies on the immune response of sheep to Chabertia ovina (Fabricius, 1788).


Common injuries in connection with conditioning exercises.


The health hazards of pollution.

The health hazards of pollution.


Concomitant immunity and host antigens associated with schistosomiasis.


Disposal by dilution? An ecologist's viewpoint.


The microbial breakdown of pesticides.

The microbial breakdown of pesticides.


Fluorescent antibody technique for quantitation of minor cell population.


Recovery of spirochagetes in the monkey by passive transfer from human late sero-negative syphilis.


A study of the relationships between the sensitivities of Neisseria gonorrhoeae to sodium penicillin G, four semi-synthetic penicillins, spiramycin, and fusidic acid.


Progress in the federal medical services.


The relation of axon sheath thickness to fiber size in the central nervous system of vertebrates.


Unit analysis of inputs to cingulate cortex in awake, sitting squirrel monkeys. I. Exteroceptive systems.


Population dynamics of Telenomus fariai (Hymenoptera: Scelionidae), a parasite of Chagas' disease vectors. V. Parasite size and vital space.


The 209th clinical meeting held on the 2nd April, 1971. Myeloproliferative disorder.


Performance of baby monkeys on the Hebb-Williams closed field maze learning task.


Motor skills of infant rhesus monkeys with thalidomide-induced forelimb malformations.


Early behaviors in hand-reared squirrel monkeys (Saimiri sciureus).


Differential reinforcement of latency (DRL) in phenylketonuric monkeys.


Pathological findings in the adrenal gland of Chacma baboons--160 consecutive cases.


Thoracic duct drainage in the vervet monkey and Chacma baboon.


Health problems encountered at the University of Stellenbosch primate colony.


Diagnosis of bovine mastitis by radial immunodiffusion.


The preparation of broad spectrum antisera for use in the characterization of serum proteins by immunodiffusion techniques.


Brucella melitensis strain Rev I as a vaccine for cattle.


Rabies in Otavi and Tsumeb, South West Africa.


Macroglobulinaemia in the dog, the canine analogue of gamma M monoclonal gammopathy.


Note on the statistical aspects of the proportion method for determining the drug-resistance of tubercle bacilli.


Nosematosis in a cat: a case report.

Nosematosis in a cat: a case report.


The neuroleptics. 6. Clinical and experimental electroencephalography.


A new type of Pseudomonas aeruginosa isolated from choleraic stools--preliminary observations.


The neuroleptics. 5. Animal behavior.

The neuroleptics. 5. Animal behavior.


Intrahypothalamic localization and onset of production of thyrotrophin releasing factor (TRF) in the albino rat.


The use of weight charts in the promotion of adequate nutrition.


The effect of malnutrition on growth, metabolism and final form.


Nutritional constraints on growth and development in current Indian dietaries.


Malnutrition in Uganda.

Malnutrition in Uganda.


Urinary 'hydroxyproline index' and plasma amino acid ratio in undernourished children.


Growth and development in the under-privileged sections in the Bombay area.


Observations on malnutrition and mental development.


Experimental circumferential compression injury of primate spinal cord.


A case of Nosema cuniculi infection in a goat.


A note on the basis of differentiation of cholera and eltor vibrios.


Fine structural alterations in transitory traumatic paraplegia.


Characterization of somatic cells by determination of their volumes with a Coulter counter.


Effects on offspring of maternal malnutrition in the rat. In: lipids, malnutrition & the developing brain.


The developing brain and the damage inflicted by malnutrition: an introduction. In: lipids, malnutrition & the developing brain.


Visual receptive field organization of single units in the visual cortex of monkey.


The effect of inferotemporal cortex ablations on eye movements of monkeys during discrimination training.


Short axon neuronal subsystems in the visual cortex of the monkey.


The treatment of retinoblastoma.

The treatment of retinoblastoma.


Peptidase activity and peptide metabolism in Escherichia coli.


Central control of movement. How can one discover the relative functional roles of pyramidal inputs to alpha as compared to gamma motoneurons?


The effect of cell size on the reaction of uranium acetate, mercuric chloride and cyanogen iodine with a strain of Pseudomonas aeruginosa.


The metabolism and enzymology of fluorocarbohydrates and related compounds.


Cancer of the breast. Staging and end results.


Cancer of the breast. Endocrine ablation, hormone therapy and chemotherapy.


Surgery of the small intestine in the adult.


A clinical and biochemical study of 12 cases of acromegaly with special reference to plasma I.R.I. and FFA on glibenclamide administration.


Production of gonadotrophin, oestrogens and progesterone by the primate placenta.


Hypersensitivity diseases of the lungs due to fungi and organic dusts.


The effects of atherosclerosis on the transmission of ultrasound.


Secondary ischaemic brain damage after head injury.


Fine structure of the developing epithelial attachment of human teeth.


Hypothalamic and pituitary injury.

Hypothalamic and pituitary injury.


Conditional responding as a paradigm for observational, imitative learning and vicarious-reinforcement.


The development of animal models for studies in Parkinson's disease.


The immunology of nematode infections. Trichinosis in guinea-pigs as a model.


The time and place of meiotic crossing-over.


Metabolism of 131 J -labelled albumin in patients with acute infectious liver diseases.


Behavior and allelic variations in enzyme activity and coat color at the C locus of the mouse.


Evolution of serum protein polymorphisms.


Carbonic anhydrase activity of acinar cells separated from guinea pig submandibular gland.


Chelaton in the treatment of generalized interstitial calcinosis.


Macroglobulinemia in chronic rheumatoid arthritis.


Ultrastructural and physiological basis of nephron pharmacology.


The rat heart phosphorylase system in experimental Chagas' disease.


Incentive reimbursement experiment.

Incentive reimbursement experiment.


Isolation and characterization of antigens of Aspergillus fischeri.


ATP-sulfurylase from Penicillium chrysogenum. I. Purification and characterization.


Purification and characterization of a thyroglobulin reactive phytoprecipitin from Pisum sativum.


Preparation and purification of microbial proteases with special reference to the bacilli.


Purification and characterization of a protease produced by Streptococcus faecalis var. liquefaciens.


Transfer of a learned form discrimination in the infant and adult monkey.


A double-blind trial of disodium cromoglycate (Intal) in the treatment of bronchial asthma. The result of a double-blind crossover trial with disodium cromoglycate (Intal) in 22 patients, nine with extrinsic asthma and 13 with intrinsic asthma, is reported. While eight extrinsic asthmatics showed considerable symptomatic improvement, only five of the intrinsic group improved while on disodium cromoglycate. Twelve out of 13 patients with symptomatic improvement had associated decrease in airway obstruction as measured by the FEV(1).It is concluded that disodium cromoglycate is useful in the treatment of asthma, particularly of the extrinsic type.


The effects of separation and reunion on the behavior of mother and infant squirrel monkeys.


Effects of age and stimulus conditions on the emotional responses of rhesus monkeys: differential responses to frustration and to fear stimuli.


Studies of undernutrition in the young rat: methodological considerations.


The influence of nutrition on neural and behavioral development. I. Critical review of some data on the growth of the body and the brain following dietary deprivation during gestation and lactation.


Microbiological assay of streptomycin in feeds.


Colorimetric determination of carbaryl in wettable formulations.


Automated steam distillation and fluorometry for screening for carbaryl as 1-naphthol in fruits and vegetables.


Humoral antibodies in human volunteers injected with experimental immunizing antigen against Chagas' disease.


Behavior of chlorinated naphthalenes in analytical methods for organochlorine pesticides and polychlorinated biphenyls.


The effect of surface adsorbants on the rate of crystal formation of hydroxyapatite precipitates.


Reactions by differentially raised rhesus monkeys to noxious stimulation.


The anatomy of the resonating mechanism in howling monkeys.


Goeldi's monkey Callimico goeldii Thomas 1904 preying on snakes.


Hydronephrosis of pregnancy: a naturally occurring disorder in non-human primates closely resembling that in man.


Observations on baboons, Papio anubis, in an arid region in Ethiopia.


Behaviour of the adult males in a troop of free-ranging chacma baboons (Papio ursinus).


Social entrainment of the feeding behavior in monkeys.


Serum antibody and eosinophil changes after treatment of human Manson's schistosomiasis with niridazole or hycanthone.


Red cell and serum proteins of talapoin, patas and vervet monkeys.


Indigenous concepts of causation and methods of prevention of childhood diseases in a rural Malay community.


An improved stool thick-smear technique for quantitative diagnosis of Schistosoma mansoni infection.


Conservation of nonhuman primates in 1970.


Problems of trustees, administrators and medical staffs.


Cancer chemotherapy.

Cancer chemotherapy.


Gene regulation networks: a theory for their global structure and behaviors.


Autonomic innervation of the lung musculature of a toad (Bufo marinus).


Cancer statistics, 1970.

Cancer statistics, 1970.


Autonomic innervation of the pulmonary vascular bed in a toad (Bufo marinus).


Liposarcoma.

Liposarcoma.


Medical syndromes associated with malignant tumors.


Unproven methods of cancer treatment.

Unproven methods of cancer treatment.


Epidermoid carcinoma of the gum: a 20-year survey.


Subcellular distribution of diamine oxidase.


Mydriatic response to phenylalanine, tyrosine, dopa, and dopamine in Bufo viridis.


Penetration of insecticides through the isolated midgut of insects and mammals.


In vitro experiments with chlorhexidine on pure bacterial and fungal cultures from the mouth.


Minor epilepsies of childhood.

Minor epilepsies of childhood.


Change of fitness by selection for a quantitative character.


Semiquantitative determination of polychlorinated biphenyls in tissue samples by thin layer chromatography.


Esterase specificity and sensitivity to organophosphorus and carbamate pesticides: factors affecting determination by thin layer chromatography.


Semiautomated liquid chromatographic determination of clopidol in poultry feed.


Effect on eggs of applications to poultry of pesticide formulations contaminated with chlorinated hydrocarbons.


Organ proteins from human pancreas, heart and brain.


Isolation of Listeria monocytogenes from brain specimens of domestic animals in Ontario.


Serum complement component C'3 values in patients with various diseases at a military hospital.


Accuracy of pulse rates counted for fifteen, thirty and sixty seconds.


Intravenous hyperalimentation.

Intravenous hyperalimentation.


Coexistent hypothyroidism and idiopathic thrombocytopenic purpura.


Neuromuscular disease and military personnel.


Thromboembolic complications after anticoagulant withdrawal.


The bacterial contamination of indriven bone fragments associated with craniocerebral missile wounds in Vietnam.


General anesthesia for outpatient dental surgery in a military population. I. Pilot study.


A contemporary and futuristic view of the Doctor of Veterinary Medicine (DVM).


Ocular toxicity of newer industrial metals.


Major General Howard McCrum Snyder, USA (Ret.).


High-energy electrons in bacteria.

High-energy electrons in bacteria.


Branched electron-transport systems in bacteria.


Reproductive adaptations in macaques.

Reproductive adaptations in macaques.


A behavioral correlate of blood-group discordance in dizygotic twins.


Depressed resistance to tetracycline in Staphylococcus aureus.


Factors affecting the adsorption of a pyocin by cells of Pseudomonas aeruginosa.


Aspects of the action of novobiocin on Staphylococcus aureus and Bacillus megaterium.


Effect of hydrogen-ion concentration on osmotic-tolerance of alkaline and fertile soil aspergilli.


A latent biosynthetic pathway in lactic acid bacteria and its role in resistance to autolysis under conditions of lysine-deficiency.


Sporulation of Bacillus megaterium: roles of metal ions.


Immunological characteristics of heat-killed Streptococcus type 1--sonic fractions obtained by zonal fractionation.


Motion detection in man and other animals.


The cerebellum of galago and tupaia. II. The early postnatal development.


Quantitative studies of the release of purine compounds following stimulation of non-adrenergic inhibitory nerves in the stomach.


Role of metals in snake venoms for hemorrhagic, esterase and proteolytic activities.


Pharmacological effects of carbaryl. I. The effect of carbaryl on the synthesis and degradation of catecholamines in the rat.


Drug dependence and phenotypic masking in Gram positive and Gram negative bacteria.


The effects of alcohols and sugars on the swelling rate of cells of Pseudomonas aeruginosa in various salts.


Pseudomonas culture longevity: control by phosphate.


Drug-induced changes in the interphase nucleus.


The phylogeny of primates from a karyological point of view.


Neuroendocrine regulation and biochemical aspects of the induction of amphibian metamorphosis.


Histological and biochemical studies on prostatic tissue of mammalians.


Obstetric mishaps in marmosets.

Obstetric mishaps in marmosets.


Comparison of lipid and lipoprotein patterns in primates.


The Cercopithecus monkey disease in Marburg and Frankfurt (Main), 1967.


Some ideas about the phylogenetic relationships of the Tinamiformes, based on protein characters.


Increased variability in the progeny of plants with variegated leaves and a possible explanation.


The regional deposition of inhaled aerosols in man.


Retention kinetics of inhaled fused aluminosilicate particles.


Chronic exposure of cynamolgus monkeys to fly ash.


The evolution of evaluation in medical administration. The implications of escalating costs in the hospital and health services.


Quantitation of secretory IgA in chronic pulmonary disease with particular reference to coal workers' pneumoconiosis.


Effect of 2,4-dinitrophenol on frequency of recessive lethal mutations induced by irradiation under aerobic and anaerobic conditions in Drosophila melanogaster.


Study of the polymorphism of the proteins of a hemolyzate of procine erythrocytes by immunoelectrophoretic analysis. II. Inheritance and distribution of variants of the PhB system in populations of pigs.


Nonhomologous pairing and nondisjunction of chromosomes of the first and second pairs in the oogenesis of Drosophila melanogaster XX females.


Comparative study of the genetic activity of analogs of nucleotide bases and redox coenzymes. I. Absence of mutagenic effect of some derivatives of purine, pyrimidine, and dihydropyridine in experiments with Drosophila melanogaster.


Genetic effect of chronic gamma-irradiation of Drosophila melanogaster males.


Spontaneous chromosome aberrations in bone marrow cells of monkeys.


Amino acid fortification.

Amino acid fortification.


Recent advances in the field of red cell structure.


Studies on marsupial proteins. VI. Evolutionary changes of beta-globins of the macropodidae and the amino acid sequence of beta-globin from Potorous tridactylus.


Observations on diagnostic kits for the determination of calcium in serum.


A new dispenser for adsorbents in thyroxine and cortisol determinations by competitive protein binding radioassay.


A new in-vitro blood test for determining thyroid status: the effective thyroxine ratio.


A study of the determination of 5-aminolevulinate hydro-lyase (delta-aminolevulinate dehydratase) activity in hemolysates of human erythrocytes.


Filipin-induced inhibition of fructoilysis and motility in monkey spermatozoa.


Virulence attenuation and other biological modifications in multiple drug resistant tubercle mycobacteria.


Antibody response in rabbits following intranasal and parenteral administration of birch pollen.


Cryoglobulins. II. The biological and chemical properties of cryoproteins in acute post-streptococcal glomerulonephritis.


Antibody-induced lysis of nucleated cells in agar gel.


Inhibition of migration of normal guinea pig blood leukocytes by homologous immune gamma 2-globulin in the presence of specific antigen.


Antigen mediated transformation of rhesus lymphocytes in immediate and delayed hypersensitivity.


Proceedings: Cross reactions between mycobacterial antigens.


Reactions of human sera with tissue particles.


Hapten inhibition of passive antidextran dextran anaphylaxis in guinea pigs. Role of molecular size in anaphylactogenicity and precipitability of dextran fractions.


An attempt to transfer delayed allergic contact sensitivity to DNCB with plasma.


Proceedings: "Mycobacterium tuberculosis" immunogens.


Serum immunoglobulins in beta-thalassaemia after splenectomy.


Serial estimation of serum, urine, and leukocyte muramidase (lysozyme) in monocytic leukemia.


Proceedings: Factors controlling the adjuvant or immunosuppressive action of antigens in complete Freund-type mixtures.


The effects of mustine hydrochloride on the colony forming units of murine bone marrow.


Phytohemagglutinin and hematopoietic stem cells in the mouse.


Association of multiple haematological disorders (acute myeloblastic leukaemia, papaproteinaemia, and thalassaemia in a 46,XX-46,XXqi female.


Organ blood flows of the fetal, newborn and adult rhesus monkey: a comparative study.


Fetal growth retardation produced by experimental placental insufficiency in the rhesus monkey. I. Body weight, organ size.


Specific cytolytic activity of lymphocytes: effect of antibodies against complement components C2, C3, and C5.


Mechanism of synchrony induction. 3. Changes of water-soluble and water-insoluble protein fractions involved in synchronous rounding in Tetrahymena pyriformis.


Mechanical ventilation of the newborn infant. II.


Benign chronic gastric ulcer on the greater curvature: brief historical review.


Mechanism of synchrony induction. IV. Accumulation of a special protein in the induction process of synchronous rounding in Tetrahymena pyriformis.


Determination of age in monkeys (Macaca irus) on the basis of dental development.


Breeding the stump-tailed macaque, Macaca arctoides.


A mobile shelving unit for laboratory animal cages.


Vitamin B12 deficiency in captive monkeys and its effect on the nervous system and the blood.


Interstitial nephritis in the spiny mouse (Acomys cahirinus) associated with Klossiella sp. infection.


Albinism.

Albinism.


Partial deletion syndromes of chromosome 18.


Intraocular juvenile xanthogranuloma. Report of a case.


Chorioretinal burn: body temperature dependence.


Rifampicin.

Rifampicin.


Use of colistin sulfate ophthalmic solution in therapy of pseudomonas ocular infections.


Ocular Toxocara canis. I. Experimental immunology.


Blocking of 5-methoxy-n-dimethyltryptamine-induced EEG alerting in the rabbit by previous administration of antiserum to this compound.


Factors influencing the 51cr-labelling of erythrocytes. Evaluation of the Signette method.


Effect of high sucrose concentrations on mitochondria: analysis of mitochondrial populations by density-gradient centrifugation after fixation with glutaraldehyde.


Newborn infant cry and nonhuman primate vocalization.


Radioiodine-labeled proteins in the serum of patients treated with 131I for thyroid disease.


Autoradiographic localization of radioactivity in rat brain and pituitary after injection of 3H-estradiol during postnatal development.


Ocular pathology of Trisomy 18.

Ocular pathology of Trisomy 18.


Immunological aspects of respiratory allergy in budgerigar (Melopsittacus undulatus) fanciers.


Disodium cromoglycate: laboratory studies and clinical trial in allergic rhinitis.


The effect of disodium cromoglycate on pulmonary function in extrinsic bronchial asthma over 12 months.


In vitro and in vivo inactivation of reagins with mercaptans.


Recurrent brain stem encephalitis. A clinico-pathological report.


Rheumatoid arthritis. A potentially crippling disease that may attack at any age.


pH-dependent changes in mitochondrial membrane structure.


Acid-base titration across the plasma membrane of Micrococcus denitrificans: factors affecting the effective proton conductance and the respiratory rate.


Studies on the transition of the cristal membrane from the orthodox to the aggregated configuration. II. Determinants of the orthodox-aggregated transition in adrenal cortex mitochondria.


Phototaxis in Euglena. VI. Correlations between ATP production by light and phototactic rates.


Flash photolysis of flavins. IV. Some properties of the lumiflavin triplet state.


The effect of glutaraldehyde on light-induced H+ changes, electron transport, and phosphorylation in pea chloroplasts.


Materials for hygienic assessment of salt composition in drinking water. Communication 6. Effect of consumption of magnesium salts with drinking water on ossification processes in growing animals.


Separation and identification of menaquinones from microorganisms. Simple thin-layer chromatographic procedures are outlined for the separation, isolation, and characterization of a complex of lipophilic naphthoquinones. Procedures are also described for the quantitative recovery of naphthoquinones from thin-layer plates. The general usefulness of the described methods is demonstrated by their application in the analysis of menaquinones from several microorganisms. The methods allow distinction between menaquinones varying in side-chain length, degree of saturation, and geometry, as well as in the presence or absence of ring methyl groups.


A gel-precipitin test for the diagnosis of varicella. Varicella may be difficult to distinguish clinically from smallpox. Because of this difficulty, much anxiety has occurred when cases of chickenpox are misdiagnosed as smallpox in areas where smallpox is not endemic. Surveillance of smallpox has also been complicated in areas where eradication programmes are in progress. A gel-diffusion test has been developed that can detect varicella-zoster (V-Z) antigen in vesicular fluid. This simple test, which can be performed in the field, identified V-Z antigen in vesicular fluid in all 14 cases of varicella or zoster that were tested. No reactions were observed with vaccinia precipitin antigen. The production of V-Z precipitin antigen in tissue culture provided a positive control that yielded lines of identity with vesicle fluid. This material was also used to screen human sera for suitable antisera for the test.


The conservative management of the partial thoracic stomach (hiatus hernia) in children.


A procedure enhancing the sensitivity of routine agar-gel techniques for HAA detection.


Depression of contact sensitivity by Friend and Riley viruses.


Radiobiological considerations for pions in radiotherapy.


The frequency of hepatitis associated antigen (HAA) in sera of patients with rheumatoid arthritis.


Epilepsy.

Epilepsy.


Trauma to the central nervous system.

Trauma to the central nervous system.


The parietal sagittal suture.

The parietal sagittal suture.


Classification and nomenclature of animal viruses, 1971.


The influence of hypophysectomy on the plasma calcium level in EDTA-induced hypocalcemia.


Synthesis of viral products by cell-free extracts.


Increased cerebrospinal fluid pressure during therapy for diabetic acidosis.


Osmotic equilibrium between extracellular fluid and cerebrospinal fluid during treatment of hyperglycemic, hyperosmolar, nonketotic coma.


Evolutionary aspects of bacterial resistance to chloramphenicol.


Organochlorine insecticide residues in fish--fall 1969 National Pesticide Monitoring Program.


Chlorinated hydrocarbons in livers of fishes from the northeastern Pacific Ocean.


National food and feed monitoring program.


Insecticide usage and residues in a newly developed great plains irrigation district.


Insecticide residues in a stream and a controlled drainage system in agricultural areas of southwestern Ontario, 1970.


Complications associated with blood transfusion.


Antibacterial nitrofuran derivatives. 2. 5-Nitro-2-furaldehyde aminoacethydrazones.


Antibacterial nitrofuran derivatives. 3. 5-Nitro-2-furaldehyde piperazinoacylhydrazones.


Taxonomy and nomenclature of viruses of vertebrates.


Irrelevant tactics, caudate lesions, delayed response performance in squirrel monkeys.


Cellular growth in infantile malnutrition.


Total joint replacement of the knee joint.


Synthetic antibacterials. 3. Nitrofurylvinyl-1,8-naphthyridine derivatives.


Interparoxysmal aspect of routine electroencephalographic tracings in epileptics with generalized convulsive seizures.


The Marburg virus (vervet monkey agent).


Spatial and object reversal learning in monkeys with partial temporal lobe ablations.


Frontal cortical epilepsy. Electroclinical correlations.


Bacterial production and destruction of histamine in foods, and food poisoning caused by histamine.


Protein-calorie malnutrition in Candelaria, Colombia. I. Prevalence; social and demographic causal factors.


Bacterial and fungal flora of normal conjunctiva.


Growth of bacteriophage phi 105 and its deoxyribonucleic acid in radiation-sensitive mutants of Bacillus subtilis. Growth of phage phi105 and its deoxyribonucleic acid (DNA) was studied in radiation-sensitive mutants of Bacillus subtilis. The recA gene is required for optimal prophage induction with mitomycin C and for infectivity of prophage DNA. rec B gene is required for marker rescue from mature DNA. The importance of bacterial genes for phage DNA activity seems to depend on phage DNA structure.


Sanitation and quarantinization procedures for imported monkeys with reference to viral diseases.


First Holloman symposium on primate immunology and molecular genetics. Introduction.


Using primates in medical research. 2. Recent comparative research. Cardiovascular diseases.


Antigenic factors characteristic of human immunoglobulin G, detected in the sera of non-human primates.


IgD myeloma L-type. Immunochemical study of the first Brazilian case.


Experiments in monkeys with human leukaemia.


Using primates in medical research. 2. Recent comparative research. Psychology and psychiatry.


The current role of non-human primates in surgical research.


Tissue typing in primates.

Tissue typing in primates.


Studies with antilymphocytic serum in monkeys.


Preliminary note on mycoplasma in primates.


Using primates in medical research. 2. Recent comparative research. Control of tuberculosis.


Quarantine of vervet monkeys.

Quarantine of vervet monkeys.


Natural treponematosis of the African primate.


Disease in laboratory personnel associated with vervet monkeys. 2. Isolation of the causal agent.


Disease in laboratory personnel associated with vervet monkeys. 1. A general report on the outbreak.


Disease in laboratory personnel associated with vervet monkeys. 3. Experimental infections of monkeys.


Supplying wild primates to the laboratory.


Using primates in medical research. 1. Husbandry and technology. Baboons.


Using primates in medical research. 1. Husbandry and technology. Selection of species for various uses.


Using primates in medical research. 1. Husbandry and technology. Breeding.


Artificial rearing of baboons.

Artificial rearing of baboons.


Artificial rearing of macaques.

Artificial rearing of macaques.


Paracrystal formation in cell cultures infected with adenovirus type 2. Large rod-shaped structures corresponding to paracrystals were seen in the nucleus, cytoplasm, or both of adenovirus type 2 (Ad2)-infected cells by immunofluorescence staining with antibody prepared against purified Ad2. In exception to this, Ad2-induced crystals did not stain with either hexon or fiber antibody. The crystalline structures were first observed in Ad2-infected Vero cells at 28 hr with a maximum number at 70 hr postinoculation. The kinetics of paracrystalline formation closely paralleled the experimental synthesis of infectious progeny virus. Acridine-orange staining revealed the lack of nucleic acids associated with the crystal. Also, the paracrystals stained intensely with phenanthrenequinone, suggesting that they are composed of basic proteins. Interferon induced by Newcastle disease virus from African green monkey kidney cell cultures was used to pretreat Vero cells prior to Ad2 infection. This resulted in inhibiting the formation of viral-induced paracrystals in 97% of the cells and reduced virus yields by 95%. The African green monkey kidney cell culture interferon did not reduce Ad2 yields in HeLa cell cultures or display any virus inhibitory activity in rabbit kidney cell cultures. Staining procedures, fluorescent-antibody tests with whole virus, hexon or fiber antibody, and interferon studies suggested that the paracrystals were viral-directed and composed of basic proteins (possibly core proteins).


Evolution of the catarrhine primates at the macromolecular level.


Disease in laboratory personnel associated with vervet monkeys. 4. Collection and shipment of vervet monkeys.


Using primates in medical research. 1. Husbandry and technology. Tranquillization and anaesthesia.


Using primates in medical research. 1. Husbandry and technology. Macaques and guenons.


Klossiella hydromyos n. sp. from the kidneys of an Australian water rat (Hydromys chrysogaster).


Pathology of measles in rhesus monkeys.

Pathology of measles in rhesus monkeys.


Inactivation of nocardiophages phi C and phi EC by extracts of bacteriophage-attachable cells. Cultures of several species of Nocardia, including N. erythropolis Mat-Ce and Mat-cE mating strains, were extracted with solvents in an attempt to isolate an inactivating complex for nocardiophages phiC and phiEC. Ethanol was the only solvent found effective in solubilizing an inhibitory substance. Inactivating extracts were obtained from the cells of all species to which the phage were able to attach. After extraction of whole cells or cell wall preparations, the phage could not effectively attach to them. Both phages phiC and phiEC were inactivated by the same complex. However, phage phiEC inactivation was 10-fold greater than phiC inactivation. The velocity of inactivation was about 4.1 x 10(2) plaque-forming units per microgram per minute for phiC and 1.1 x 10(3) plaque-forming units per microgram per minute for phage phiEC. The cell extracts required divalent cations for phage inactivation. The inhibitory capacity of the cell extracts was reduced or lost by the activity of proteolytic enzymes, Tween 80, 2-mercaptoethanol, thymol, and sodium lauryl sulfate. Boiling the extract for 10 min did not alter its activity. The inactivating substance was postulated to be a lipoprotein of considerable complexity, unique in the ease with which it is solubilized from host cells by ethanol.


Neural mechanism controlling skeletal muscular activity and its unsolved problems.


High-speed techniques in biological research and their utilization in experimental head injury.


Cannibalism and the new milestones in medicine.


The detection of microfilariae using the capillary haemotocrit tube method.


A comparative study of peste des petits ruminants and Kata in West African Dwarf goats.


Allergic epididymo-orchitis in guinea pigs and bulls.


Multiple esophageal diverticula associated with spasm and stricture.


Autoimmune thyroiditis: historical aspects and laboratory diagnosis.


Excerpts from the monthly Surgery Committe Meeting, The Memorial Hospital, Danville.


The management of Hodgkin's disease.

The management of Hodgkin's disease.


Pseudomonas aeruginosa infections in an artificial respiratory ward.


Incidence and hygienic importance of Pseudomonas aeruginosa in water.


A new mycobacterium species: Mycobacterium asiaticum n. sp.


Are adrenergic overactivity and splanchnic vasoconstriction the prime pathophysiological events in shock?


Effects of endotoxin and E. coli shock on the metabolism of lipids and carbohydrate.


Effects of endotoxin on the vascular architecture of intestinal mucosa.


Explant of the first four micromeres of Bufo arenarum eggs.


Fertilization of jelly-less Bufo arenarum oocytes in the presence of high sperm concentrations.


Immunochemical and physiologic insulin lack during lethal E. coli septicemia in the subhuman primate.


Normal and abnormal determination in the imaginal discs of Drosophila, with special reference to the eye discs.


Pathways of glucose breakdown during Bufo arenarum ontogenesis.


Progress in the leukemias.

Progress in the leukemias.


Role of the pancreas in the pathogenesis of circulatory shock.


The lung lesion in shock.

The lung lesion in shock.


Metabolic activation of N-hydroxy compounds by conjugation.


Studies of the neurological basis of intellectual function.


The neuropathology of temporal lobe epilepsy.


The place of surgery in the management of extracranial cerebrovascular disease.


The propagation of epileptic events.

The propagation of epileptic events.


Some molecular parameters influencing rate of reduction of azo compounds by intestinal microflora.


The conjugation of aminoazo dye metabolites with a tripeptide and specific soluble proteins of the liver soluble cytoplasm of the rat.


Ventral tier thalamic nuclei.

Ventral tier thalamic nuclei.


The oxidation of polyamines in higher plants.


Complement fixation by the F(ab')2-fragment of pepsin-treated rabbit antibody.


RBE variations for high energy electrons.


In vitro delayed hypersensitivity in normal and hyporeactive patients.


Solubilization of IgM-kappa specific surface material from Burkitt lymphoma cell lines.


Some biological effects of IgM anti-Rh (D).


Whole-body measurement techniques at the Swedish National Institute of Radiation Protection.


Rat kidney UDPG: alpha-1,4-glucan alpha-4-glucosyltransferase.


Interconversions of cardiac muscle glycogen synthetase.


Micromethods for protein and enzyme analysis.


Mesoectodermal dysplasia of the iris and cornea, mental retardation and myopathy: a sporadic case. The Rieger syndrome is characterized by mesoectodermal dysplasia of the iris and cornea, dental defects, in some cases short stature, abnormal external ears, hypertelorism, arachnodactyly, polydactyly, scoliosis, kyphosis, imperforate anus, umbilical hernia, myopathy and in a few cases mental retardation. This report presents a sporadic case of the Rieger syndrome, the findings in which include the characteristic ocular anomalies, shortness of stature, mental retardation, absent dental defects and a peculiar, heretofore unobserved, myopathy.


A review of selected inherited corneal dystrophies associated with systemic diseases. The normal transparency of the cornea permits detailed in vivo study of several human pathologic conditions. Many systemic diseases are associated with corneal dystrophies which are manifested by haziness, opacification, crystalline deposition, or discoloration. Although these abnormal states can sometimes be seen grossly, biomicroscopy with slit lamp illumination is necessary for an exact morphologic description. Only precise delineation can lead to an accurate diagnosis of the corneal disorder and thus provide clues for an associatkd systemic disease.


Norrie's disease.

Norrie's disease. Norrie's disease is an X-linked disease presenting bilateral blindness at birth or during the first few months of life. A white retrolental membrane is seen initially, later the eyes usually become phthisic. Dementia or psychosis appears in about 25% and sensory hearing loss present in 1/5 or 1/4 of the blind males. Carriers are clinically unaffected. The main differential diagnoses comprise retinoblastoma, retrolental fibroplasia, toxoplasmosis, falciform detachment, juvenile retinoschisis, sex-linked microphthalmia, sex-linked cataract and congenital retinal detachment.


Corneal clouding in mucopolysaccharidosis VI (Maroteaux-Lamy syndrome).


Enlarged corneal nerves in the syndrome of medullary carcinoma of the thyroid, multiple neuromas and in some bilateral pheochromocytoma.


Genetic variants of thyroxine-binding globulin (TBG). New genetic variants of decreased TBG binding capacity observed in our studies are described and discussed in relation to previously reported variant types. Although single factor inheritance may explain the strikingly different phenotypes found in X-linked variants it cannot explain the wide variation discerned in the majority of individuals in our control population or the phenomenon of nonpentrance in one of our families. TBG binding capacity may be a polygenic trait with many loci contributing to the observed phenotypes.


Further electroretinographic studies of patients with mucopolysaccharidoses. Electroretinographic studies were performed on many of the patients studied by Gills et al in 1965. An additional 13 patients with mucopolysaccharidoses were also studied. The ERG is normal in all patients with the Morquio syndrome (MPS IV), the Maroteaux-Lamy syndrome (MPS VI) and pseudo-Hurler polydystrophy. The ERG is abnormal in patients with the Hurler syndrome (MPS I), the Sanfilippo syndrome (MPS III) and the Scheie syndrome (MPS V). Some patients with the Hunter syndrome had normal ERGs while others had abnormal ERGs.


Studies of serum thyroxine-binding globulin (TBG).


Facial cleft.

Facial cleft.


Neurofibromatosis of von Recklinghausen.


Comments on frontonasal dysplasia, ocular hypertelorism and dystopia canthorum. The mean canthal index values of patients with frontonasal dysplasia are tested for differences in facies A, B, C, and D. A general discussion of ocular hypertelorism and dystopia canthorum is presented. Ocular hypertelorism is considered a sign which may occur in a variety of disorders. Quantitative methods for determining ocular hypertelorism are critically reviewed.


Investigation of a case of oculocutaneous albinism. One conclusion reached from a study of a case of tyrosinase negative albinism was that the structure of melanizing apparatus was normal. Its regulation and ability to be stimulated was functionally normal also. The characteristic defect in albinism must be somewhere in the availability or inhibition of tyrosinase based on a genetically induced structural defect of the protein pattern.


The biology of pigmentation.

The biology of pigmentation. Genes are one of the most important control mechanisms of the process of melanin pigmentation and, therefore, changes in pigmentation are important markers of genetic aberrations. Melanin pigmentation is related to four biologic processes: 1) formation of melanosomes in melanocytes; 2) melanization of melanosomes in melanocytes; 3) secretion of melanosomes into keratinocytes and 4) transport (by keratinocytes) of melanosomes within lysosome-like organelles.


Fluorographic study of diaphragm movements in patients with bronchial asthma and emphysema under the influence of hydrocortisone hemisuccinate.


On the problem about the characteristics of forced expiration. (Third communication).


A comparative study on culture of Trichomonas vaginalis.


Rachitis in children up to 2 years of age in Addis-Abeba (Ethiopia) and some peculiarities in its clinical picture.


Radioindicator investigation on the degree of transcutaneous resorption in the various allergic skin tests.


On the changes of the protein content of cerebrospinal fluid in tumors of cerebrum and spinal cord.


Some morphological prerequisites for the regulation of cerebral circulation of the blood.


Changes in the motility of the prepyloric region of the stomach in acute metabolic acidosis in rabbits.


Subfractioning of the third lactate dehydrogenase (LDH3) from tissues of guinea-pigs.


On the dynamics of formation of an endogenous factor, stimulant of the humoral immunogenesis.


Permeability of ultra-violet and infrared rays through cotton and synthetic textiles.


Localization of glutamate dehydrogenase activity after electrophoresis in different conditions.


Action of some essential oils on Trichomonas vaginalis.


Values of serum glucoproteids in mental diseases.


On the coagulogram in patients with diabetes.


Talpa europea -- reservoir of Trichinella spiralis in our contry.


Nomograms for the determination of the theoretical values of the different forced expiratory volumes.


Functional investigations of liver by means of labeled with 131J rose Bengal in acute metabolic acidosis in rabbits.


Acid--base balance of the blood in patients with hepatic cirrhosis.


Histochemical investigations of some enzymes in the liver in ulcerative disease of the stomach and duodenum.


A rare finding as hernial content in the inguinal hernia in suckling's age.


Finger print pattern types of Bulgarian Mohammedans.


The renal cortex index and its value in the diagnosis of chronic pyelonephritis.


A method and an apparatus for indirect lighting up by mediastinoscopy.


Fatty acid biosynthesis by isolated mitochondria from Drosophila melanogaster.


Immunochemical analysis of the origin of a sex-specific accumulated blood protein in female houseflies.


Influence of nutritional changes on lipoprotein lipase activity. II: The effect of high fat intake on levels of enzyme of rat adipose tissue.


An unusual eye-ear syndrome with renal abnormality.


Genetic heterogeneity in the Waardenburg syndrome. Waardenbury syndrome is divided into three groups: Type I, with dystopia; Type II, and "pseudo-Waardenburg" syndrome, without dystopia; the third has unilateral congenital ptosis. Using Waardenburg's original variables a, b and c, ratios a/b and c/a, Cotterman's L function, newly described indices X and Y and some phenotypic manifestations, a confident neat separation of each type can be obtained. New cases of all types and electron micrographs of the hair pigment anomaly are described.


The nosology of mental retardation: including the report of a survey of 1378 mentally retarded individuals at the Walter E. Fernald State School. The mentally retarded here are divided into two groups. The first group consists of the mildly retarded (IQ 50-70) whose deficit, for the most part is a reflection of the expected variability of human intelligence and of adverse sociocultural factors. The second and smaller group includes the moderately, severely and profoundly retarded (IQ smaller than 50), most of whom have brain damage. A new clinical survey indicates that acquired brain disease is the most common cause (26 percent), followed by chromosome disorders (18.7 percent).


An oculocerebrofacial syndrome.

An oculocerebrofacial syndrome. A syndrome of mental retardation, microcephaly, a mongoloid slant to the palpebral fissures, microcornea, strabismus, myopia, optic atrophy, high-arched palate, preauricular skin tags and small mandible is described in four (including one set of twins) of seven sibs born to unaffected, nonconsanguineous parents of German ancestry. An autosomal recessive mode of inheritance seems most likely.


The Dyggve-Melchior-Clausen syndrome.

The Dyggve-Melchior-Clausen syndrome. An  18-year-old mentally retarded girl with short-trunked dwarfism is described as a case of the Dyggve-Melchior-Clausen syndrome. This disorder is characterized by distinctive skeletal radiographic changes, particularly a lacey appearance of the iliac crest. This syndrome appears to be inherited as an autosomal recessive trait. Reports of several cases with similar radiographic changes but without mental retardation suggest heterogeneity within this syndrome.


Nosology of epilepsy: some comments on the problem. In the classification of epilepsy, there is no uniform system which can successfully combine consideration of seizure type, etiology, anatomic substrate and other factors such as circumstances of occurrence, age and the electroencephalogram. The most logical system is seen to be similar to that proposed by an international committee. In such a system each observational set of data is classified in accordance with its own characteristics, and correlations made between data obtained by different means of observation.


Monotherapy with rifampicin in pulmonary tuberculosis.


Sanfilippo syndrome.

Sanfilippo syndrome.


Biochemical approaches to the nosology of nervous system defects, III. In an ever larger number of neurologic conditions, the diagnosis depends on biochemical procedures. These range in complexity from simple screening tests on urine or blood, to analyses of nervous tissue lipids or metabolic studies or explants of brain tissue. Examples of each these are provided.


Blood groups and anthropology.

Blood groups and anthropology.


Ionic calcium.

Ionic calcium.


Use of immunoelectrophoresis and immunodiffusion in clinical medicine.


Effects of injection of sodium nitrite in Drosophila melanogaster.


Cytogenetic effects of 2,4,5-trichlorophenoxy-acetic acid on oogenesis and early embryogenesis in Drosophila melanogaster.


Interallelic complementation for pyrimidine requirement in rudimentary mutants of Drosophila melanogaster.


Athletic injuries at the University of Toronto.


Further studies of bovine syncytial virus.


Bovine trypanosomiasis and lymphocytosis parallel studies.


The epizootiology of Marek's disease.

The epizootiology of Marek's disease.


Hemic neoplasms in cold blooded animals: lymphosarcoma in the pike Esox lucius.


Herpesvirus Saimiri induced malignant lymphoma: recovery of the viral agent from the fatally affected animals.


Evidence for a virus in human sarcomas.

Evidence for a virus in human sarcomas.


Chemistry of cephalosporin antibiotics.

Chemistry of cephalosporin antibiotics.


Studies on the conjectural virus nature of human leukemia in experiments on monkeys.


Thermophilic aminopeptidasesfrom Bac. stearothermophilus. II. Aminopeptidase I (AP I): physico-chemical properties; thermostability and activation; formation of the apoenzyme and subunits.


Studies on bacterial proteases. Amino acid composition and optical rotatory dispersion of neutral protease of Bacillus subtilis var. amylosacchariticus.


Studies on bacterial proteases. Chemical modification of tyrosyl residues of neutral subtilopeptidase amylosacchariticus.


The binding characteristics of transcortin, thyroxine binding globulin and pre-albumin in Jamaicans.


Studies on carcinogenic bifunctional aminoazo dyes. II. The hydration and electron density at K'-region of diaminoazo dyes.


Cycloserine.

Cycloserine.


Studies on carcinogenic bifunctional aminoazo dyes. III. Synthesis and physico-chemical properties of (N',N'-dimethyl-4'-amino)-, (4'-amino)- and (N'-acetyl-4'-amino)-N,N-dimethyl-4-aminoazobenzene.


Trimethadione and human teratogenesis.

Trimethadione and human teratogenesis.


India: UN mission evaluation of the family planning program.


Planetary quarantine. Sterilization of space hardware.


Evolutionary rate of cistrons and DNA divergence.


Phylogenetic measurement in procaryotes by primary structural characterization.


Hominoid evolution as judged by fibrinopeptide structures.


Immunohistochemistry of glomerulonephritis.


The measurement of glomerular filtration pressure from sieving data for macromolecules. It is possible to derive the GFP from sieving data by two means and with the following qualifications: 1. Assuming the membrane isoporous, it is possible to calculate GFP by applying Poiseuille's law. The analysis of the sieving curve should then be limited to molecules with a radius between 21 and 41 A. 2. Assuming a log-normal distribution of pore radii, it is possible to obtain a value for GFP by computation. In this case the values for phi higher than 0.7 will not be considered in the calculation of sigmaE used to determine the most satisfactory adjustment of the calculated sieving curve to the experimental data. Although the second method allows a perfect adjustment of the curves, it gives more scattered results than the first for the calculation of GFP. However, a close correlation exists between both sets of results.


Segmental hypoplasia of the kidney in children. Of 36 cases of segmental hypoplasia of the kidney in children and adolescents anatomic lesions are described and a detailed definition of the abnormality is given. The disease occurs predominantly in girls and show no familial tendency. Segmental hypoplasia may be separated into four groups: (1) unilateral, (2) bilateral and asymmetrical, (3) bilateral and symmetrical, and (4) unusual presentation such as latent disease or association with other anomalies. The importance of differentiating these four groups is indicated not only with respect to the clinical course and prognosis but also with regard to treatment.


Intrarenal distribution of blood flow.

Intrarenal distribution of blood flow.


Clinical diagnostic value of lysozymuria.


Factors influencing immediate prognosis in acute renal failure, with special reference to prophylactic hemodialysis. Five hundred patients with acute renal failure were admitted to the Department of Nephrology of Necker Hospital between 1966 and 1970; 279 of them were treated before and 221 after beginning systematic prophylactic hemodialysis. The frequency of complications and the survival rate between both groups were compared. No significant improvement was obtained in patients with severe pre-existing diseases or extensive extrarenal lesions; such patients usually died from nonuremic complications before, or despite, dialysis. However, adequate treatment of severe septic shock, when present, was an important factor in improving the immediate outcome. Early and frequent dialysis significantly reduced the frequency and intensity of uremic symptoms such as gastrointestinal hemorrhage. The mortality due to gastrointestinal bleeding decreased from 14% before to 5% after prophylactic hemodialysis. The number of deaths due to septicemia was also substantially lowered from 24 to 12%. Overall mortality was reduced from 42 to 29%. The mortality rate decreased significantly in all categories of patients, particularly in surgical cases (from 54 to 38%) and in traumatic cases (55 to 33%). Simultaneously, the better use of antibiotic therapy, better prophylaxis of sepsis, and better nutritional care were important factors in the overall improvement in prognosis.


Infection in acute renal failure.

Infection in acute renal failure. The results are reported of the incidence, severity, and description of infectious complications in 646 cases of acute renal failure (ARF). Infection was felt to represent an important cause of ARF in 34% of the cases. However, the frequency and extent of the infection varied according to the biologic classification. It was present constantly in postabortion ARF, was frequent in medical and in postoperative ARF, and was rare in traumatic and postpartum ARF. The renal lesions vary according to the cause of the infections. Staphylococcus septicemia, leptospiral infections, and rickettsial infections are the causes of interstitial nephritis; whereas gram-negative septicemia, probably via infectious shock, leads more readily to tubular lesions. Hemolytic septicemias most often cause tubular necrosis, although this is usually reversible. When the initial clinical picture is complicated by disseminated intravascular coagulopathy, bilateral cortical necrosis is a distinct possibility. During the established phase of ARF, infections are equally frequent, whether primary or secondary. The most frequent complications are septicemia and bacteremia--or local complications, most often pulmonary or urinary tract infections. The organisms are mainly Staphylococcus (often mephicillin-resistant) and gram-negative, usually E. coli. The most effective treatment is a combination of cephalothin and gentamicin. Pseudomonas infections are the most difficult to treat. The frequency of these serious infections and the difficulty with antibiotic therapy, often dangerous in renal insufficiency, stress the importance of preventive treatment of prophylactic measures. Infection was primarily responsible for 19% of the deaths in our series and may be also largely responsible for some of the persistent residual renal functional impairments.


Immunosuppression in the treatment of glomerulonephritis.


The genesis of glomerulonephritis in renal transplants. It appears that in human renal isografts glomerulonephritis in the transplant may be a recurrence of the original disease. In the allograft, nephritis may be either recurrence, an intrinsic part of the rejection process itself, or acquisition de novo of the disease. A number of parallels to both antiglomerular basement membrane disease and circulating antigen-antibody complex disease in the animal model are suggested, but with the possible exception of an occasional demonstration of anti-GBM disease, proof that such mechanisms operate in the glomerulonephritis developing in the human allograft is at present lacking.


The functioning of Henle's loop as studied in microperfusion experiments on desert rodents (Meriones shawii duvernois).


Evidence for a hormone other than aldosterone which controls urinary sodium excretion.


Waldenström's macroglobulinaemia: a report of five cases.


A case of chronic active hepatitis with some unusual features.


Study of vegetative innervation in the oesophagus. I. Perivascular endings.


On the sympathetic nature of some forms of Recklinghausen's disease: a study of six cases.


A new hearing test applicable to the crying newborn infant. Hearing tests in newborn infants hitherto described have been designed to elicit a response to a sound when the infants are quiet or asleep. It has been accepted that there was no response when they were crying. The present observation describes the effect of a sound stimulus on the crying newborn infant. I have observed that if the infant is not extremely distressed it is possible to get a response regularly. What I did was to make a continuous sound at a distance of 15 to 30 cms. and the babies regularly stopped their cry sequence. The vocal intensity required was less than that of the baby's cry. This quieting response suggests auditory attention or a reflex mediated at a cortical level. The response to this vocal sound is analysed in terms of its effect on heart rate and respiration. It is compared with the effect of a pure tone stimulus of different pitch. It seems to be elicited with notes of low pitch and occurs independent of age or birth weight. The implications and possible long-term significance of the response will be discusses.


Rheumatic diseases of the central nervous system in children. During childhood cerebral disturbances may not infrequently be a first manifestation of rheumatism. Mention should primarily be made of chorea which, as is reasonable to assume, is of rheumatic origin, followed by rheumatic encephalitis, particularly with its hyperkinetic and myoclonic forms. Important to diagnosis are very exact laboratory results and the immunobiological tests. With regard to further maturation the most different syndromes may occur and obtain in cases of neurological disturbances of rheumatic origin. Hyperkinetic forms were observed in small children, diencephalic syndromes chiefly in schoolchildren and adolescents.


Toxoplasmosis of the central nervous system in children. The clinical symptoms and signs of 17 children with congenital toxoplasmosis of the brain are reported. Moreover the neuropathological lesions of 8 cases were given. The clinical findings of 10 children with acquired toxoplasmosis were tabulated. Problems concerning the diagnosis and differential diagnosis of toxoplasmosis of the central nervous system were discussed.


Jaw function in some old world monkeys.

Jaw function in some old world monkeys.


Conception of the development of the motor organization in child with reference to cerebral palsy and its therapy. It is often put forwards that the motor behaviour may be explained on the basis of motor patterns defined with reference to metric space. Merton, who interpretes the gamma loop as a length servo-mechanism, gives a neurophysiological basis to the above conception. The critical study of Merton's theory, our personal work and the analysis of the motor development of the infant lead us to disagree this view. The notion of pattern seems worthkeeping, but provided that the organization is described in terms of regulation of movements and not in terms of position, or length of muscle. A metric spatial reference is not always present. When it is needed, it is not included in the postural regulation. In other words, this reference is not obtained by a postural servo-mechanism. It is obtained first by trial and error in relation to external object and this is so in the young child. It is much later that an evaluation of distance is integrated into action, deriving from a conceptual acquisition of it by the child. The obvious progression of motor behaviour from birth poses the question of respective roles of maturation and learning. A review of very recent works lead us to think that maturation is not a sufficient explanation. Being by the fact, lead to emphasize learning, it becomes evident to us that application of the psychological conceptions of J. Piaget gives the best explanation of the facts. The above analysis in normal child are applied to cerebral palsied child, giving explanations of problems and offering better guides for therapy.


Pattern analysis of motor development and of its disorders. Posture or movement is considered as a structure of integrated patterns. A motor pattern is a spatio-temporal configuration in the nervous system indipendent of the mechanisms of muscles, bones and joints which bring about the movement. Kinesiology, which is a study of movement, should include the analysis of this patterned structure. A method is described "motoscopic examination" which allows one to assess the disorders of the patterned structure of movement. Pattern Kinesiology is particularly important during motor development in children where the building up of motor behaviour and of its disorders appears to be an interaction of reflexes and automatisms. The motoscopic observer can draw his reference from certain typical behaviours of the experimental animal, of the developing child and of neurological patients. Pattern analysis is a better clinical tool than the traditional examination of muscle tone disorders for the early diagnosis of cerebral palsy, for which it may provide new taxonomic criteria.


Recent advances in the study of infant behaviour and their implications. Embryology has shown that fetal studies may give some information on past development and about the latest state of development of individuals. Also, an important conclusion is that the neonate should be considered a complexly functioning adult in the embryonic stage rather than an amorphous living creature.


Clinical aspects of developmental neurology. It is very important that children with cerebral lesions be presented not only to the pediatrician, but also to the specialist in childhood neurology. An evaluation is quite complicated as children with positive anamneses and early signs of neurological dysfunction are normal in later childhood and vice versa. Infants showing normal initial development may in later childhood exhibit various cerebral disorders. Developmental neurology is perhaps a key to the prognosis of neurological dysfunction in the maturing child.


Ataxia-telangiectasia. (Clinical and immunological aspects). This syndrome was defined by the authors in 1947. Earlier publications of similar disease descriptions were by Syllaba and Henner (1926), Louis-Bar (1941). The authors at present have a stock of 253 cases. The cardinal symptoms of this phakomatosis are: Cerebellar ataxia which begin in infancy and take a slowly progressive course. In the late stages free walking and standing are no longer possible. Progressive atactic speech disorders, cerebellar atrophy in the pneumoencephalogram. Slowly progressing symmetrical skin and mucosal telangiectasia in the face and especially on the conjunctivae at the age of 3 to 6 years. Relapsing sinopulmonary infections with a tendency toward the development of bronchiectases. Apraxia of eye movements. Atrophy of facial skin and premature graying of hair. Recessively hereditary disorder with a high familial manifestation. This syndrome combines the spinocerebellar degeneration, phakomatoses, and infantile dementia processes. Such other conditions as abnormity or absence of thymus, reduction in gamma globulins, amino-aciduria, autosomal-recessive inheritance suggest a genetically determined "error of metabolism".


A prospective study of mental and motoric development in premature children with a birth weight less than 2000 grammes. The prognostic value of pathological neurological signs. As a conclusion I will say that a careful and repeated neurological examination enables us to make an early diagnosis of brain damage in premature children, but neither the history of the neonatal period, the separate clinical signs, nor the study of the psycho-motoric development is conclusive for the diagnosis. The prognosis seems to be good if the neonatal period is without abnormalities.


Disorders of language development, with particular reference to central deafness. Many disorders may result in delay of language development. There is on the one hand a large group of children with bilateral peripheral deafness, most of whom will be amenable to appropriate treatment, and on the other a group, possibly more numerous, who have a variety of disorders of speech and language, varying from lack of speech associated with severe mental retardation to more specific defects, such as congenital dyslexia and developmental articulatory dyspraxia. These disorders are probably due to a defect of cerebral function at the highest level and in these children no-one will have suspected deafness or have suggested that there is an abnormal response to auditory stimuli. Some children will start life with such an abnormal response but as they grow older will cease to show the characteristics of deafness. This group is analysed and it is suggested that some may be diagnosed as suffering from central deafness. The E. E. G./Audiogram is useful in the differenciation of these children from those with perpheral deafness, especially at an early age when co-operation is limited, or when these are severe emotional disturbances or infantile psychoses. This technique will be briefly discusses. Children with central deafness may be included among those with disorders of language development, but it is possible that this disability may sometimes result from a failure of integration at a cortical level. The reason for suggesting this diagnostic category is to stress that these children do initially behave in a similar way to those who are perpherally deaf.(ABSTRACT TRUNCATED AT 250 WORDS)


Some problems concerning psychiatric sequelae in brain-injured children. The report concerns 100 children (64 boys, 36 girls, 2-15 years old) with psychiatric disorders due to mechanical injuries of the brain. The symptoms occurred for the most part within 1-3 years after the injury. They were: encephalopathy (35 cases), characteropathy (5), neurosis (16), epilepsy (44). Epilepsy was the most important posttraumatic problem, particularly the focal form of epilepsy. There was conformity between focal changes in the EEG curves and the clinical character of seizures. The age of the child at the moment of the injury, the gravity of the injury, and previous organic disorders caused by abnormal delivery seem to be the main factors determinant of the severity of the psychiatric sequelae of a trauma. Mechanical trauma seems to activate former latent lesions of the brain due to abnormal delivery.


Early diagnosis of brain damage in prematures with birthweight below 1250 g in the light of follow up examinations. A follow up study of 67 prematures born with a low birthweight (1250 g or less) was made since July 1962 at the Premature Department and Aftercare Clinic of the Medical School in Warsaw. The study consisted of physical, psychological and anthropometrical examinations. Results revealed a high percentage of children with developmental disturbances such as brain damage, behavioural and visuo-motor disturbances. No evident, statistically significant interrelation between these disturbances and the course of the neonatal period could be found. The interrelation was more evident between these disturbances and the course of pregnancy. Haemorrhage in the first half of pregnancy seemed to be a most serious complication. It is difficult to predict the chances of a normal psychophysical development of the smallest prematures. Such prognosis depends on many different and complicated factors.


Developmental disturbances in children of mothers with dysthyreosis--epidemiological aspect. It is the purpose of this work to investigate the possible presence of epidemiological links between dysthyreosis in the mother and developmental disturbances in the child. The clinical material comprised 51 children and 50 mothers. In 60% of cases data on gynaecological disorders could be elicited in the past history of the mothers (spontaneous abortions, premature births, stillbirth etc.). The developmental disturbances in the children showed the pattern of a multisystemic encephalo-endocrinopathy. They were arranged in characteristic clinical syndromes, the age of the child being considered as a criterion (newborn period, infancy, early childhood). The authors suggest that in the mechanism of this encephalo-endocrinopathy damage of the foetal thyroid gland by antithyroid antibodies of the mother could play a role. Further investigations along these lines are being conducted.


A note on the school problems of brain injured children. The school difficulties of brain injured children are greater in the first and third classes while in the second class they are mostly reduced. Both subjective and objective causes of this phenomenon are discussed. At the beginning of the first class subjective difficulties of the child, connected with the transition to organized collective school-work, prevail. Later, more objective conditions--the demands of the school curriculum--begin to interfere. For the pupil of the second class mere attendance has become a commonplace. As to the subject matter, it is mostly a repetition and brushing up of the material taken in the first class. The new difficult subject matter in the third class requires a great deal of drill. This overtaxes the attention, mechanical memory, and patience of the brain injured pupil. He is supposed to be fully responsible for his difficulties and reacts with neurotic symptoms and behaviour disorders. The temporary solution of the problem lies in the individual adjustment of the teaching program and in the individual help by teachers and parents.


Psychopathology of children with minimal brain injuries. Children with the syndrome of minimal brain injuries, i.e. with psychic sequelae of a slight, diffuse lesion of the cerebral tissue, suffer from disorders of neural activity on different levels, from "primary disorders" such as of simple motor reactions and sensory defects to the most complicated performances such as speech and concept formation. It is assumed that mild lesions of the reticular formation of the brain stem is the common neurophysiological denominator of the whole syndrome. The psychopathological pictures, however, develop only from the continuous interaction of an organically conditioned state with unsuitable educational methods of the irritated parents and with other pathogenic factors of the external environment. The pictures can be divided into four basic diagnostic groups: behaviour disorders, neurotic manifestations, psychopathic traits, and psychotic manifestations.


On the syndrome of psychomotor instability. This syndrome is most commonly met with in brain-injured children. It shows several aspects of psychopathological features. The most impressive is restlessness along with the poor coordination of movements. Signs of psychic infantilism can be seen in the form of uncontrolled emotional outbursts of the child under frustration and as a lack of persistence in striving towards a goal. Another typical feature is their impulsiveness. There is a further attempt made to give a more detailed analysis of this concept. The work of Freud, Levin, Luria, Eysenck and Cohen relative to this topic is briefly mentioned. An account on some results of research at Psychiatric Clinic in Prague follows. By means of systematic observation and questionnaires children in nursery schools were grouped into impulsives, social extraverts and introverts. Some differences in performance were predicted in reaction time, learning and relearning of a central set etc. Analysis of variance between the aforesaid groups has revealed some significant differences.


A study on the late consequences of a brain trauma in early childhood (BTEC). Among children causing educational difficulties there is, according to the author, a much greater number of encephalopaths with BTEC than it is commonly assumed. Better diagnostic methods help more and more often to diagnose organic changes in the so-called difficult children. The present report gives a clinical picture of encephalopathy after BTEC. Studies were made on a group of 500 children who had suffered brain trauma of various kinds during their foetal life or early childhood. Symptoms of the infantile psychoorganic syndrome and character disorders were the most significant features of encephalopathy after BTEC. Furthermore, the children presented changes in the EEG and a lowered IQ score (not very markedly, as a rule). Focal neurological changes were rare. Basing on the fact that character disorders are a most typical feature of encephalopathy, the author classified encephalopaths as belonging either to the group of bradykinesia or that of hyperkinesia. Each of these groups has further been subdivided into those comprising the common, the asocial and the anxious type, according to the encephalopaths' attitude toward their environment.


Schistosomiasis: experimental surgical removal of adult worms.


Effects of nitroglycerin on left ventricular volumes and wall tension in patients with ischaemic heart disease. Since the dimensions of the ventricles are related to both myocardial tension and myocardial oxygen consumption (MVO2), the effects of nitroglycerin on the left ventricular volumes and left ventricular haemodynamics were studied in patients with ischaemic heart disease. The ventricular volumes were estimated using the constant infusion technique (indocyanine green) of Shaffer (1964). Sublingual administration of nitroglycerin (0.6 mg.) resulted in a significant reduction in cardiac output (27%), mean systolic pressure (21%), left ventricular end-diastolic pressure (63%), stroke volume (27%), left ventricular end-diastolic volume (26%), and left ventricular work (41%). Both calculated circumferential myocardial force (40%) and the myocardial tension (33%) decreased during systole, while the pressure-time index decreased by 27%. A similar decrease was also found in the contractile element work (42%), and mean circumferential fibre shortening rate (22%). Thus, this study has shown that the major determinants of MVO2, i.e. myocardial wall tension, the velocity of contraction, and contractile element work, decrease significantly after administration of nitroglycerin.


Adaptation of intestinal lactase in the rat. A study was undertaken to adapt intestinal lactase activity in adult rats. After 5 to 8 weeks on a 30% lactose diet, a significant increase in jejunal lactase activity was observed. A similar, but smaller rise was found using a 30% glucose diet.


Chemoprophylactic agent in schistosomiasis: 14,15-epoxygeranylgeraniol. The occurrence of all-trans (-)-14,15-epoxygeranyl-geraniol in Pterodon pubescens Benth. is established, and its prophylactic activity against infection by Schitsosma mansoni demonstrated. Two other diterpenes present in the oil are inactive.


Effect of intra-uterine devices on corpus luteum function.


Pediatric home care program: review of two and a half years' experience at the Children's Hospital of Winnipeg.


Tuberculous lymphadenitis in pigs.

Tuberculous lymphadenitis in pigs.


Persistence of group A streptococci as related to penicillinase-producing staphylococci: comparison of penicillin V potassium and sodium nafcillin.


Comparative studies on cortical representation of vision.


Growth of the human fetus. II. Abnormal growth in twins and infants of mothers with diabetes, hypertension, or isoimmunization.


Exocellular ribonuclease from Streptomyces aureofaciens. I. Isolation and purification.


Exocellular ribonuclease from Streptomyces aureofaciens. II. Properties and specificity.


Studies on the inhibition of neutral proteases by 1,10-phenanthroline.


Subunits of aldose reductase from Rhodotorula.


Preparation and properties of water-insoluble derivatives of ribonuclease T1.


Hormonal activity of the rat placenta in the absence of dietary protein.


Effect of actinomycin D on hormones that control the release of thyrotropin from the anterior pituitary glands of mice.


Feeding gastrostomy in small premature infants.


Extrasalivary lymphoid abnormalities in Sjögren's syndrome (reticulum cell sarcoma, "pseudolymphoma," macroglobulinemia).


On the nature of the renal concentrating defect in malnutrition.


Antianginal drugs. Part III. Clinical use of nitroglycerin.


The use of the uncompensated high energy photon beam in radiation therapy.


A protozoological method for detecting clinical vitamin B6 deficiency.


Vitamin E-responsive macrocytic anemia in protein-calorie malnutrition. Measurements of vitamin E, folic acid, vitamin C, vitamin B12 and iron.


Malnutrition in northern Thailand.

Malnutrition in northern Thailand.


Is hypoglycemia an important complication in erythroblastosis fetalis?


Trypsinogen deficiency disease.

Trypsinogen deficiency disease.


An indirect hemagglutination test for group B meningococcus.


The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo.


Studies of arboviruses by agar gel diffusion.


Effects of persantin and nitroglycerin on myocardial blood flow during temporary coronary occlusions in dogs.


Severe nephrosis in older male rats given calcium disodium edetate.


Blood groups ABO and Rh (D) factor in the rheumatic diseases.


Organic nitrate explosives as monoamino-oxidase inhibitors. Studies in vitro.


In vitro studies on polysaccharides of Mycobacterium tuberculosis and delayed hypersensitivity.


Conversion by isoniazid of hyperacute to chronic pulmonary tuberculosis in mice. I. Survival times of mice and course of the chronic disease; bacterial populations and responses of the host.


Mycoplasma pneumoniae infections in University of Wisconsin students.


Tuberculin hypersensitivity associated with papulonecrotic tuberculids.


Renal artery dysplasia as a cause of hypertension in neurofibromatosis.


Grand mal convulsions subsequent to marijuana use. Case report.


Benzo[d,e]testosterone acetate: a new synthetic steroid with dissociation of biological activities.


Variation in the deoxyribonuclease activity in synchronously growing and dividing mass cultures of Tetrahymena pyriformis GL.


Rabbit zygote transport and development following various methods of ovulation induction.


Isolated ciliary structures of Euplotes patella.


An ultrastructural study of hepatic granulomas and schistosome egg shells in murine hepatosplenic schistosomiasis mansoni.


Mitochondrial budding and morphogenesis of cytoplasmic vacuoles in hepatocytes of children with the Hurler syndrome and Sanfilippo disease.


Immune precipitin reactions between an anti-human myoglobin antiserum and several purified primate myoglobins.


Salmonellosis complicating schistosomiasis in Egypt. A new clinical appreciation.


An electron microscopic study of the liver parenchyma and schistosome pigment in murine hepatosplenic schistosomiasis mansoni.


A comparison of oral and parenteral activity of hycanthone and lucanthone in experimental infections with Schistosoma mansoni.


Schistosomiasis. Extracorporeal filtration in the treatment of experimentally infected baboons.


Treatment of experimental and clinical schistosomiasis with hormonal inhibitors of ovulation.


The concentration of copper in the liver of African children with marasmus.


Haemodynamic effects of angina pectoris, and of nitroglycerin in normal and anginal subjects.


Radiotherapeutic management of localised Hodgkin's disease involving the mediastinum.


Bilharzial polypi of the urinary bladder.


A study of tuberculosis antibodies by bentonite flocculation. Bentonite particles sensitized with concentrated human Old Tuberculin were used for detection of circulating antibodies to M. tuberculosis in human sera.There was no sharp distinction between the titres of patients with active and inactive tuberculosis, but progressively higher antibody titres accompanied increased severity of infection. The sera of 95.3% of the patients studied had a titre of 1:8 or higher. This level was considered to be the minimal significant titre indicative of the presence of metabolically active bacilli in old and new lesions. Tuberculin-negative controls and syphilitic sera were negative. A common zone of incidence in the 1:8-1:32 range was found where differentiation between tuberculin-positive healthy people and patients with tuberculosis was not possible; however, titres of 1:64 or more were found only in tuberculous patients. The antibody under study is heat-labile.


The effect of gold salt on lysosomal enzymes of the peritoneal macrophage.


Listeria meningitis.

Listeria meningitis.


Effects of dimethyl sulfoxide on dimethylbenzanthracene-induced carcinogenesis in the hamster cheek pouch.


A chromatographic modification of the tetracycline fluorescence test for gastric cancer.


Enzymatic abnormalities in diseases of sphingolipid metabolism.


Maternal anti-Rh(D) and the D-negative fetus.


"In use" study of buffered glutaraldehyde for cold sterilization of anesthesia equipment.


The influence of pregnancy and oral contraceptive steroids on the concentration of plasma proteins. Studies with a quantitative immunodiffusion method.


Antenatal serologic assessment of severity of hemolytic disease due to anti-Rh.


Gm and InV group factors in antibodies with different specificities.


A comparative study of nitroglycerin and propranolol.


Antigenic structure of saprophytic mycobacteria.


A new component from the cell wall of Streptomyces griseus. I. The role of streptomycin in the life of Streptomyces griseus.


Observations on biochemical changes in irradiated spores of Bacillus cereus.


Transduction in Bacillus subtilis.

Transduction in Bacillus subtilis.


Primary macrocryogelglobulinemia. Remission with adrenal corticosteroid therapy.


Protein-calorie deficiency and disorders of the endocrine glands.


Adrenal glucocorticoids after twenty years. A review of their clinically relevant consequences.


Management of cleft lip and palate problems.


Congenital abnormalities of the infant larynx.


Congenital hearing impairment.

Congenital hearing impairment.


Congenital lesions of the head and neck.


The treatment of acute middle ear infection in children.


Nasal symptoms of mucoviscidosis.

Nasal symptoms of mucoviscidosis.


Allergy of the upper respiratory tract.

Allergy of the upper respiratory tract.


The diagnosis of head and neck masses in children.


The diagnosis and treatment of suppurative sinus disease in children.


Respiratory infections and antimicrobial therapy.


Reconstructive middle ear surgery for children.


The indications for tonsillectomy and adenoidectomy.


Septorhinoplasty in children.

Septorhinoplasty in children.


Otoplasty for children.

Otoplasty for children.


Foreign body accidents involving the air and food passages in children.


Acute traumatic injuries of the oropharynx, laryngopharynx, and cervical trachea in children.


Pediatric sinus problems.

Pediatric sinus problems.


Radiographic anatomy of the nasal sinuses.


Benign tumors of the nasal sinuses.

Benign tumors of the nasal sinuses.


The management of oroantral fistulas.

The management of oroantral fistulas.


Transantral decompression for malignant exophthalmos.


Trans-sphenoidal hypophysectomy.

Trans-sphenoidal hypophysectomy.


Acute and chronic sinusitis.

Acute and chronic sinusitis.


The surgical anatomy of the nasal sinuses.


Surgical drainage of the antrum.

Surgical drainage of the antrum.


The Caldwell-Luc operation.

The Caldwell-Luc operation.


Surgery in allergic sinusitis.

Surgery in allergic sinusitis.


Overview of the management of the congenitally deaf child.


Surgery of the frontal sinuses.

Surgery of the frontal sinuses.


The genetics of congenital deafness.

The genetics of congenital deafness.


Congenital middle ear anomalies.

Congenital middle ear anomalies.


The development of an auditory function.


Inner ear pathology in congenital deafness.


The pediatric management of the congenitally deaf child.


Clinical application of acoustic impedance measurements.


Audiological evaluation of the congenitally deaf infant.


A high risk registry to find congenital deafness.


Surgery of congenital deafness.

Surgery of congenital deafness.


Education of the deaf: the otolaryngologist's role.


Hearing aids for children.

Hearing aids for children.


New concepts in congenital deafness.

New concepts in congenital deafness.


The Regional Medical Program for Heart, Cancer and Stroke.


Professional liability insurance.

Professional liability insurance.


Proposed medical liability act with cover letter.


Georg Wilhelm Steller. Physician-naturalist on the Bering expedition to Alaska.


Liver scanning.

Liver scanning.


Peripheral vascular surgery in review.

Peripheral vascular surgery in review.


Medical activity--St. Mary's Mission.

Medical activity--St. Mary's Mission.


Blood viscosity and fibrinogen concentration following cerebral infarction.


Evoked cortical potentials in patients with stroke.


The use of hyperbaric oxygenation in the treatment of cerebral ischemia and infarction.


Natural history and physiological basis of adolescent obesity.


Nutritional significance of the non-nutrient components of food. Introductory remarks.


Naturally occurring toxicants in foods.

Naturally occurring toxicants in foods.


Physiologically significant food contaminants.


Nutritional status and biological response.


Collaborative research in pediatric practice.


Physical activity and anthropometric measurements of obese adolescents.


Household products--obsolete containers--inevitable poisonings.


Nutritional impact of modern food processing.


Effect of a combined nutrition education and physical fitness program on the weight status of obese high school boys.


Immunologic tolerance to defined antigens and haptens. Introductory remarks.


Postmaturity.

Postmaturity.


Specificity of immunologic unresponsiveness.


Induction and termination of immunologic tolerance to protein antigens.


Study of adrenal function in children with meningitis.


The first report of the value of fish liver oil as a cure for rickets.


Nonenzymatic activation of the fibrinolytic enzyme system.


Prolonged hypertension following cessation of desoxycorticosterone therapy in congenital adrenal hyperplasia.


Measurement of accessibility of protein chromophores by solvent perturbation of their ultraviolet spectra.


On a simple method of preventing sore throat.


Tissue fibrinolytic activity studied by a histochemical method.


Specificity of immunosuppression by antimetabolites.


How well do patients take oral penicillin? A collaborative study in private practice.


Follow-up study of exchange transfusion for hyperbilirubinemia in infants in Japan.


Factors pertaining to prolonged pregnancy and its outcome.


Analysis of 1964 national register of scientific and technical personnel data for experimental biologists.


The nephrotic syndrome of infancy: clinical, morphologic, and immunologic studies of four infants.


Postnatal bone growth of infants with fetal growth retardation.


Intelligence of the unidentified phenylketonuric child.


The bobble-head doll syndrome: a "tic" with a neuropathologic basis.


Ontogeny of fibrinolysin system and its role in pathogenesis of hyaline membrane disease of infants.


Functional significance of the fibrinolytic enzyme system.


Ventilation and respiratory gas transfer of infants with increased pulmonary blood flow.


Diagnosis and treatment: the complications of steroid treatment.


Congenital hypothyroidism and prolonged neonatal hyperbilirubinemia.


Results of testing a child-resistant medicine container.


Early introduction of solid foods.

Early introduction of solid foods.


American Academy of Pediatrics Committee on Nutrition: Nutritional management in hereditary metabolic disease.


Breathholding spells.

Breathholding spells.


Treatment of tetanus neonatorum.

Treatment of tetanus neonatorum.