Cutaneous nerves in dysautonomia.

Cutaneous nerves in dysautonomia.


The management of transient tyrosinemia of the newborn.


Thrombohemolytic thrombocytopenic purpura (TTP). A disease or a syndrome?


Familial thrombocytopenia, elevated serum IgA levels and renal disease. A report of a kindred.


Adolescent food practices associated with obesity.


Familial hereditary nephropathy (Alport's syndrome).


On Danubian endemic familial nephropathy (Balkan nephropathy). Some problems.


The kidney in human leptospirosis.

The kidney in human leptospirosis.


Azathioprine in steroid-insensitive nephropathy.


Inhibition of drug metabolism by acute ethanol intoxication. A hepatic microsomal mechanism.


Fluoride metabolism in man.

Fluoride metabolism in man.


Studies of fluoride and calcium metabolism in patients with osteoporosis.


Behçet's disease. Report of twelve cases with three manifesting as papilledema.


Histiocytosis and infection with atypical mycobacteria.


Monoclonal gammopathy with hyperlipidemia.


The clinical and experimental aspects of peritoneal response to injury.


Neuroblastoma. Evaluation of the treatment of 90 children.


Chest trauma. Analysis of 685 patients.

Chest trauma. Analysis of 685 patients.


Posttraumatic venous thrombosis.

Posttraumatic venous thrombosis.


External pancreatic fistula following abdominal injury.


Pulmonary embolectomy.

Pulmonary embolectomy.


Repair of experimental hiatal hernia in dogs.


Hiatus hernia without esophageal reflux.


The nature and source of a gastric secretagogue. Observations from the obstructed portal vein.


The role of gastrocamera in the diagnosis of marginal ulcer.


Vagotomy and pyloric drainage for chronic duodenal ulcer. Long-term results.


Selective gastric vagotomy. A critical reappraisal.


Results following remedial operation for severe dumping syndrome.


Pancreatoduodenectomy for trauma.

Pancreatoduodenectomy for trauma.


Chylous ascites following pancreatoduodenectomy.


An evaluation of the effects of cartilage powder on wound healing.


Posttraumatic cerebrospinal fluid leaks.


Lipoid pneumonia. Its protean nature and clinical resemblance to carcinoma of the lung.


Cardiopulmonary resuscitation experience in a general hospital. Review of 116 consecutive resuscitative attempts during a 2 1/2-year period.


Retrograde thrombectomy for chronic occlusion of the common carotid artery.


Congenital tracheoesophageal fistula in the adult.


Acute thrombosis of the subrenal abdominal aorta.


Carotid artery cavernous sinus fistula.

Carotid artery cavernous sinus fistula.


Disposable aerosol tissue adhesive spray.


Functioning metastasis from thyroid cancer.


Further contribution to the understanding of the post-infarctual anedematous syndrome.


New lines to the treatment of male sterility.


The problem of iodine-125 for treatment of thyrotoxicosis.


Radioimmunoassay of a human pituitary prolactin in plasma.


The analysis of the endometrium of 1,000 sterile women.


The measurement of progesterone in human plasma by competitive protein-binding radioassay.


Comparative study of the histoenzymological properties of the supraoptic and paraventricular nuclei and of other nuclear regions of the hypothalamus, the epithalamus-epiphysis region and the subfornical organ.


The phenomenon of nucleolar segregation in some lesions of the thyroid cell.


The systemic and local effects of dexamethasone, triamcinolone, 6 alpha-fluorotriamcinolone, and certain of their derivatives, compared by reference to their influence on the foreign-body granuloma, on the weight of the adrenals and thymus, and on the rate of weight gain.


Adrenal function parameters and body weight gains in young rats reared with or without mother animal.


The thymic hormones.

The thymic hormones.


Ultrastructural aspects of experimental isoimmune thyroiditis and of its changes after TSH.


Serum tests for measurement of thyroid function.


Prophylaxis against exophthalmos or its progression in newly-treated thyrotoxicosis.


Interrelations between diabetes and arterial hypertension. Analysis of 1000 observations.


Activity of adrenal cortex homotransplanted into testes of adrenalectomized hamsters.


Hormone excretion in pregnancy following gonadotrophin treatment.


Comparison of the adrenocorticotrophic effect of a synthetic depot corticotrophin in normal, dexamethasone-blocked, and hypophysectomised rats.


Experience with insulin-induced hypoglycemia as a provocative test for growth hormone and cortisol secretion in children.


Effect of chlorpropamide and water deprivation on free water clearance in patients with diabetes insipidus.


Effect of heating of blood on the quantitative determination of carbon monoxide haemoglobin.


Evaluation of food additives. Specifications for the identity and purity of food additives and their toxicological evaluation: some extraction solvents and certain other substances; and a review of the technological efficacy of some antimicrobial agents. Fourteenth report of the joint FAO/WHO Expert Committee on Food Additives. Geneva, 24 June-2 July 1970.


Joint FAO/WHO Expert Committee on Nutrition. Eighth report. Geneva, 9-18 November 1970.


Specifications for the identity and purity of food additives and their toxicological evaluation: some emulsifiers and stabilizers and certain other substances. Tenth report of the joint FAO/WHO Expert Committee on Food Additives. Geneva, 11-18 October 1966.


Specifications for the identity and purity of food additives and their toxicological evaluation: some antibiotics. Twelfth report of the joint FAO/WHO Expert Committee on Food Additives. Geneva, 1-8 July 1968.


Specifications for the identity and purity of some extraction solvents and certain other substances. Joint FAO/WHO Expert Committee on Food Additives.


Occupational acroosteolysis. Report of 31 cases.


Esophageal dysfunction in diabetic neuropathy-gastroenteropathy. Clinical and roentgenological manifestations.


Mesothelioma and its association with asbestosis.


Renovascular status after renal surgery for hypertension.


Malignant nephrosclerosis in women post partum. A note on microangiopathic hemolytic anemia.


Private practice by residents in training.


Middle lobe bronchiectasis. Report of an unusual familial occurrence.


The passive voice.

The passive voice.


Cystometry.

Cystometry.


Painful swelling over right tibia.

Painful swelling over right tibia.


Clot-begotten bleeding in viral disease.


Amyloid.

Amyloid.


Deafness, electrocardiographic abnormalities and sudden death.


Aloysio Luigi Galvani (1737-1798) discoverer of animal electricity.


Glucose suppression of serum growth hormone in the diagnosis of acromegaly.


Successful treatment of hepatic coma by exchange transfusions.


Underneath the logwood tree.

Underneath the logwood tree.


Successful cardiac massage, open and closed.


Myelitis associated with an echovirus.

Myelitis associated with an echovirus.


Classification of lung cancer--to be revised.


Delivery pressure at the catheter tip.

Delivery pressure at the catheter tip.


Nephrotoxicity from cephaloridine.

Nephrotoxicity from cephaloridine.


Treatment of abdominal aortic aneurysms.


Pleiku Medical Society.

Pleiku Medical Society.


Rupture of aortic aneurysm into inferior vena cava.


Chronic pulmonary infiltration.

Chronic pulmonary infiltration.


Inflatable splints and pneumatic plastic boots.


The patient with a fatal illness--to tell or not to tell.


Relationship of cerebrovascular reactivity to degree of extracranial vascular occlusion.


Purulent pericarditis in infancy.

Purulent pericarditis in infancy.


Cerebral hemodynamics, blood gases, and electrolytes during breath-holding and the Valsalva maneuver.


Circulating anticoagulants to factor VIII. Immunochemical studies and clinical response to factor VIII concentrates.


In vitro plasma inactivation of thyrotropin releasing factor (TRF) and related peptides. Its inhibition by various means and by the synthetic dipeptide PCA-His-OME.


Manual on food and nutrition policy.

Manual on food and nutrition policy.


Subluxation of the distal radio-ulnar joint by hyperpronation.


Preparation of feeds for newborn infants by a cold method.


Focus on infant feeding. 1. Breast feeding.


Excision of a pseudocyst of the hand in a hemophiliac (PTC-deficiency). Use of a plasma thromboplastin component concentrate.


Tissue activators of plasminogen.

Tissue activators of plasminogen.


Report on long term therapy with anticoagulants.


Bovine enzootic leukosis.

Bovine enzootic leukosis.


Head-turning in the newborn: effect of feeds and lateral preference.


The iritable colon of childhood (chronic nonspecific diarrhea syndrome).


Intravascular clotting and cancer localization.


The fibrinopeptides.

The fibrinopeptides.


Elevation of factor 8 in hypercoagulable states.


Infant feeding and caries of the incisors: an epidemiological approach.


Group 3. Observations on 400 cases of acute myocardial infarction treated with Insulin, Potassium and Dextrose infusions.


Introducing solid foods.

Introducing solid foods.


Cardio-auditory syndromes. Cardiac and genetic study of 511 deaf-mute children.


Hypo (a)-gamma globulinemia (literature review).


Tuberculosis cutis in children.

Tuberculosis cutis in children.


Growth failure, deprivation, and undereating.


Nutrition for mothers and infants--economic considerations.


Nutritional requirements of infants and children with liver disease.


Formula feeding 1970.

Formula feeding 1970.


Birth weights of infants of different economic groups in Hyderabad.


Neutralization of antithrombin VI (fibrinogen breakdown products) with platelet antiheparin factor (platelet factor 4).


The biological half-life of I-131 fibrinogen.


Inheritance of factor 8.

Inheritance of factor 8.


Genetics of hemorrhagic diathesis. Discussion.


Palmo-plantar hyperkeratosis with periodontosis (Papillon-Lefèvre syndrome).


Accidental clotting of heparinised blood.


Estimation and sampling variance in the health interview survey.


The care of burned victims.

The care of burned victims.


Marantology, a needed specialty.

Marantology, a needed specialty.


New horizons in school health.

New horizons in school health.


Reserpine for tardive dyskinesia.

Reserpine for tardive dyskinesia.


Dysentery in Nicaragua.

Dysentery in Nicaragua.


Hypotension due to 5 per cent plasma protein fractions.


Altered protein binding of diphenylhydantoin in uremic plasma.


Copper deficiency in a premature infant fed an iron-fortified formula.


Peritoneal dialysis and dialysate volumes.


Energy loss in fluid therapy.

Energy loss in fluid therapy.


Sulfonamide-sulfonylurea interaction.

Sulfonamide-sulfonylurea interaction.


Drugs, doctors and deceit.

Drugs, doctors and deceit.


Heroin use in the navy.

Heroin use in the navy.


Interaction between chloral hydrate and warfarin. A report from the Boston Collaborative Drug Surveillance Program, Boston Universtiy Medical Center.


Transvenous caval interruption with umbrella filter.


Management of emotional reactions in seriously burned adults.


Pulmonary mucormycosis.

Pulmonary mucormycosis.


Diphenylhydantoin intoxication mimicking botulism.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 2-1972.


"Vibes".

"Vibes".


Rapid separation and determination of nonionic surfactants of the polyethylene glycol-monoalkyl phenyl ether-type by column liquid chromatography.


New method for prediction of partition coefficients in liquid-liquid systems and its experimental verification for steroids by static and chromatographic measurements.


Identification and estimation of neutral organic contaminants in potable water.


Combined gas-liquid chromatography-mass spectrometry study of cambendazole and related compounds.


Gas chromatography of volatiles from breath and urine.


Design studies for a biomedical gas chromatograph.


Comparison of corticosteroid derivatives by gas chromatography-mass spectrometry.


Identification of hydrocarbon pollutants on seas and beaches by gas chromatography.


Continuous determination of carbon monoxide by frontal analysis.


Coupled anion and cation exchange chromatography of complex biochemical mixtures.


Marginal incision for upper blepharoplasty.


High temperature gas-chromatographic separations using glass capillary columns and carborane stationary phases.


The fate of amputated tissues of the head and neck following replacement.


Facial fractures in snowmobile injuries.


A new method of elongation of the corner of the mouth.


Primary nostril reconstruction in complete cleft lips. The round nostril technique.


Cosmetic surgery and the university hospital.


Surgical correction of lobster-claw feet.


Orbicularis advancement flap for restoration of angle of the mouth.


Demonstration of the multiplicity of N-acetyl-beta-glucosaminidase by electrophoresis.


A molecular orbital investigation of the dipole moments of the syn and anti conformers of purine and pyrimidine nucleosides.


A cytochrome cc'-like haemoprotein isolated from Azotobacter vinelandii.


Incorporation of molecular oxygen during the biosynthesis of ubiquinone in an aerobic bacterium, Pseudomonas desmolytica.


Topography of nucleic acid helices in solutions. XXIV. Intercalation specificities of DNA and their possible role in the recognition process.


Control of pyruvate carboxylase in alloxan diabetic rats.


Particulate forms of phenylalanyl-tRNA synthetase from Ehrlich ascites cells.


The effect of glucose on the conversion of muscle phosphorylase a into b or b'.


Penicillin interaction with guanosine.

Penicillin interaction with guanosine.


The release of aspartate transaminase from mitochondria by dilute ionic solutions.


Auxin (2,4-D) stimulation (in vivo and in vitro) of polysaccharide synthesis in plasma membrane fragments isolated from onion stems.


Macromolecular assembly of chondroitin.

Macromolecular assembly of chondroitin.


Carbon-13 NMR spectra of carbon-13 enriched chlorophylls a and b.


Fourier transform C-13 NMR analysis of some free and potassium-ion complexed antibiotics.


Studies on the structure and activity of low molecular weight glycoproteins from an antarctic fish.


Dissolution of cholesterol gallstones by chenodeoxycholic acid.


Analgetic drugs--the mild analgetics.

Analgetic drugs--the mild analgetics.


The "class-action" approach to protecting health-care consumers--the right to psychiatric treatment.


Metabolic acidosis reversed by the combination of magnesium hydroxide and a cation-exchange resin.


A medical treatment for gallstones?

A medical treatment for gallstones?


Skin rashes with penicillin therapy: current management.


Methadone.

Methadone.


Committee on Maternal Welfare Aortic stenosis with sudden death.


Bone-marrow biopsy and osteoporosis.

Bone-marrow biopsy and osteoporosis.


Influence of mobilization on anticoagulant treatment.


Evaluation of digitalis toxicity by salivary electrolytes.


Making sure of TB treatment.

Making sure of TB treatment.


Skin-test reactions in patients with SSPE.


Genetic control.

Genetic control.


Corporate responsibility for medical care.


How to know if you have quality control.


Beyond responsibility: toward accountability.


Financing the cost of the new unemployment compensation benefits.


Administration of unemployment compensation is not that complicated.


Four requisites for developing HMOs.

Four requisites for developing HMOs.


Negotiating price agreements.

Negotiating price agreements.


A study of innovative staffing.

A study of innovative staffing.


Effect of duodenal acidification or exogenous secretin on gastric acid secretion stimulated by histamine, pentagastrin or human gastrin I in conscious cats.


The influence of caerulein-like peptides on gastric secretion and peptic ulcer formation in cats.


Serum collagen-like protein in patients with chronic liver disease.


Aetiological factors in pancreatic calcification in Ceylon.


Isolation of microfibrils from rat vibrissal follicles.


Storage of 5-hydroxytryptamine in megakaryocytes.


Microfilaments in epithelial morphogenesis.


A kinetic analysis of myogenesis in vitro. Conditions which yielded reproducible growth kinetics with extensive, relatively synchronous differentiation are described for chick muscle cultures. The effects of cell density and medium changes on the timing of cell fusion were examined. Low-density cultures which received a change of medium at 24 hr after plating show the highest rate of cell fusion, increasing from 15 to 80% fused cells in a 10 hr period. These optimal culture conditions were employed to reexamine two questions from the earlier literature on muscle culture: (a) can cells which normally would fuse at the end of one cell cycle be forced to go through another cell cycle before fusion; and (b) how soon after its final S period can a cell complete fusion? In answer to the first question, it was found that if the medium is changed, many cells which would otherwise fuse can be made to undergo another cell cycle before fusion. In the second case, radioautographs were made from cultures incubated with tritiated thymidine for various times at the beginning of the fusion period. These show labeled nuclei in myotubes as early as 3 hr after the beginning of the incubation period. This indicates that cells can fuse as early as the beginning of the G(1) period, and suggests that there is not an obligatory exit from the cell cycle or a prolonged G(1) period before cell fusion and differentiation during myogenesis.


A major polypeptide of chloroplast membranes of Chlamydomonas reinhardi. Evidence for synthesis in the cytoplasm as a soluble component. Electrophoresis of thylakoid membrane polypeptides from Chlamydomonas reinhardi revealed two major polypeptide fractions. But electrophoresis of the total protein of green cells showed that these membrane polypeptides were not major components of the cell. However, a polypeptide fraction whose characteristics are those of fraction c (a designation used for reference in this paper), one of the two major polypeptides of thylakoid membranes, was resolved in the electrophoretic pattern of total protein of green cells. This polypeptide could not be detected in dark-grown, etiolated cells. Synthesis of the polypeptide occurred during greening of etiolated cells exposed to light. When chloramphenicol (final concentration, 200 microg/ml) was added to the medium during greening to inhibit chloroplastic protein synthesis, synthesis of chlorophyll and formation of thylakoid membranes were also inhibited to an extent resulting in levels of chlorophyll and membranes 20-25% of those found in control cells. However, synthesis of fraction c was not affected by the drug. This polypeptide appeared in the soluble fraction of the cell under these conditions, indicating that this protein was synthesized in the cytoplasm as a soluble component. When normally greening cells were transferred from light to dark, synthesis of the major membrane polypeptides decreased. Also, it was found that synthesis of both subunits of ribulose 1, 5-diphosphate carboxylase was inhibited by chloramphenicol, and that synthesis of this enzyme stopped when cells were transferred from light to dark.


Persistence of behavior disorders in children.


Neo-oralism and the education of the deaf in the Soviet Union.


Verbal deficit in children with hearing loss.


Hyperkinesis: delineation of two patterns.


Utilization of parents in a speech correction program.


Inservice training through short term conferences.


Experiences with preschool deaf-blind children.


Changing public altitudes toward blindness.


Performance of neurologically impaired preschool children with educational materials.


Trabeculotomy and sinusotomy in enucleated human eyes.


Ocular hypertension induced by scleral suction cup.


Permeability of hydrophilic contact lenses.


Do shifts in attention change perceived locus of self?


Time-sampling caretaker and infant behaviors in the first five weeks of life.


Psychovector analysis: a new discipline within the behavioral sciences.


Amount of body movement as an indicant of task-irrelevant test anxious responses.


Differential change among sensitivity training participants as a function of dogmatism.


Effects of magnitude of sucrose and saccharine on body weight.


Negative contrast with humans as a function of emotionality.


The body schema of normal and mentally retarded children.


Note on the relationship of ordinal position, dogmatism, and personal sexual attitudes: a reply.


Anxiety, self-concept, and the semantic differential.


The psychodynamics of humor, as seen in institutionalized retardates.


Effects of a self-improvement course on self-concepts of adolescent female clients.


Children's response speed as a function of omission and delay of a customary reward.


Some personality correlates of contraceptive use among unmarried female college students.


An approach to the objective measurement of spasticity.


The Walldius prosthesis: a total treatment program.


Suggestions from the field. Don't throw away that old wheelchair.


Terminal extension exercises for the knee.


Educational programs leading to professional qualification in physical therapy.


Impact of health care changes on physical therapy practice.


Changing roles of physical therapists.

Changing roles of physical therapists.


Intracranial hypertension.

Intracranial hypertension.


The interaction of caffeine with pentobarbital as a nighttime hypnotic.


The response of brain surface pressure to hypercapnic hypoxia and hyperventilation.


Malignant hyperthermia of swine.

Malignant hyperthermia of swine.


Malignant hyperthermia of Poland China swine: studies of a myogenic etiology.


The mechanism of the negative inotropic effect of methoxyflurane on isolated rat atria.


The effects of ketamine on cerebral circulation and metabolism in man.


The cardiac pre-ejection period: a correlate of peak ascending aortic blood-flow acceleration.


Atypical cholinesterase: frequency in a Puerto Rican population.


Effects of time on ventilation during halothane and cyclopropane anesthesia.


The efficiency of partial soda-lime bypass circuits.


Forane increases bleeding in therapeutic suction abortion. The effect of forane, an anesthetic, upon uterine bleeding during therapeutic abortions was examined in 13 women, ranging in age from 19-36 years, who were 8-13 weeks pregnant.  9 received forane-70%nitrous oxide-oxygen maintained at 1.0% or .5%.  4 women received a 1.4% concentration of forane-oxygen.  No patients moved during the abortion, performed by the suction technique.  The average blood loss was 208 plus or minus 43 ml.  In pregnancies of less than 10 weeks, average blood loss was 181 plus or minus 61 ml, while women who were more than 10 weeks pregnant had an average blood loss of 251 plus or minus 55 ml.  There was a tendency toward less bleeding (85 plus or minus 13 ml) in the 4 women who received forane without nitrous oxide as compared with the blood loss of the group who used forane with nitrous oxide (262 plus or minus 53 ml).  Forane was judged to increase uterine bleeding and was therefore unacceptable as an anesthetic during suction abortions.


Increased cerebrospinal fluid pressure after ketamine.


Radiation induced meningeal fibrosarcoma.


The role of the mural coronary artery in prevention of coronary atherosclerosis.


Light and electron microscopic studies of a gastric leiomyoblastoma.


Effect of lasiocarpine on aflatoxin B 1  carcinogenicity in rat liver.


Chronic ulcerating interstitial cystitis (Hunner's ulcer). A study of 28 cases.


Linearity and frequency response of pneumotachographs.


Conversion of a disposable oxygenator into a reusable unit.


Measurement of fetal renal inulin clearance in a chronic sheep preparation.


Carotid sinus counterpressure as a baroreceptor stimulus in the intact dog.


Estimation of arterial PO2, PCO2, pH, and lactate from arterialized venous blood.


An electromechanical apparatus to seal freeze-dried tissue specimens under vacuum.


New technic for measurement of physiological parameters in conscious animals.


A nondestructive technique to measure wall displacement in the thoracic aorta.


Normal arterial blood pH, oxygen, and carbon dioxide tensions in unanesthetized dogs.


Effect of local heating and arterial occlusion on sweat electrolyte content.


Distribution of airway resistance with developing pulmonary edema in dogs.


Effect of lung inflation on bronchial length and diameter in excised lungs.


A role for the Starling (nonlinear) resistorlike action of renal proximal tubules.


Hypoxic and hypercapnic ventilatory drives in children native to high altitude.


Effect of CO2 and pH on bronchoconstriction caused by serotonin vs. acetylcholine.


Site of pulmonary vascular resistance in fetal goats.


Plasma erythropoietin in men and mice during acclimatization to different altitudes.


Acid-base balance after maximal exercise of short duration.


Transfer of inert gases and tritiated water across the sheep placenta.


Cardiac acceleration elicited by voluntary muscle contractions of minimal duration.


An examination of regenerating hepatic tissue subjected to radio-frequency irradiation.


Canine transthoracic resistance.

Canine transthoracic resistance.


Unattenuated ventilatory hypoxic drive in ovine and bovine species native to high altitude.


Radiologic seminar. 113. Empty sella turcica.


The percentage numbers game; a travesty upon medical dignity.


Direct coronary revascularization.

Direct coronary revascularization.


A new horizon in cancer therapy: immunotherapy. I.


Prevalence of plasma lipoprotein abnormalities in a free-living population of the Central Valley, California.


Hemodynamic evaluation of left ventricular function in shock complicating myocardial infarction.


Fleischner lines and pulmonary emboli.

Fleischner lines and pulmonary emboli.


Symposium: myocardial infarction 1972. 1. Introduction.


Sudden death related to myocardial infarction.


Left ventricular function in acute myocardial infarction and its clinical significance.


Coronary arteries in fatal acute myocardial infarction.


Asymmetrical hypertrophic cardiomyopathy simulating mitral stenosis.


Regional myocardial blood flow.

Regional myocardial blood flow.


Experimental myocardial infarction. X. Efficacy of glucagon in acute and healing phase in intact conscious dogs: effects on hemodynamics and myocardial oxygen consumption.


Glucose extraction by the human myocardium during pacing stress.


Medical instrumentation in peripheral vascular disease.


Bile acid synthesis in man: metabolism of 7 -hydroxycholesterol- 14 C and 26-hydroxycholesterol- 3 H. The pathways of bile acid synthesis in man were evaluated by studying the metabolism of 7alpha-hydroxycholesterol-4-(14)C and 26-hydroxycholesterol-16, 22-(3)H administered parenterally to individuals requiring external biliary drainage. Techniques for the identification of metabolites were thin-layer chromatography, column chromatography, gas-liquid chromatography with stream splitting, and crystallization to constant specific activity. It was found that both compounds were rapidly metabolized to bile acids and excreted in bile. Of the total radioactivity recovered in bile as bile acids, 87% of the 26-hydroxycholesterol-(3)H and 90% of the 7alpha-hydroxycholesterol-(14)C was found to be metabolized to both chenodeoxycholate and cholate. Compared to 7alpha-hydroxycholesterol, a greater proportion of 26-hydroxycholesterol was found to be metabolized to chenodeoxycholate. These findings indicate that both 7alpha-hydroxycholesterol and 26-hydroxycholesterol can be intermediates in the metabolism of cholesterol to bile acids in man. The observation that conversion to cholate takes place less readily after C-26 hydroxylation is consistent with previous findings in other species.


Relationship of sodium reabsorption and glomerular filtration rate to renal glucose reabsorption. Glucose reabsorption was measured in dogs in which sodium reabsorption was stimulated by obstruction of the thoracic inferior vena cava or inhibited by volume expansion with Ringer's lactate. Glucose reabsorption was much higher during periods of enhanced sodium reabsorption than during sodium diuresis. The relationship of glucose reabsorption to glomerular filtration rate was examined using data from animals that had fractional sodium excretion rates of less than 1%. Under this condition the relationship of glucose reabsorption to glomerular filtration rate is highly linear. When points obtained during sodium diuresis (C(Na)/GFR>0.1) are plotted on the same graph, glucose reabsorption at any given glomerular filtration rate is much less than during antidiuresis. Glucose reabsorption divided by glomerular filtration rate varies inversely with fractional sodium excretion. This study demonstrates that glomerular tubular balance for glucose exists in the dog and that this balance is changed when sodium reabsorption changes.


The role of cell swelling in ischemic renal damage and the protective effect of hypertonic solute. The failure of blood flow to return to the kidney following a transient period of ischemia has long been recognized. The cause of this "no-reflow" has been investigated in the rat after a transient period of total obstruction of the renal arteries. The vascular pattern of the kidneys as visualized with silicone rubber injection shows a diffuse patchy ischemia throughout the kidney, which persists after release of the obstructed renal artery. Electron microscopic studies of ischemic kidneys showed that all cellular elements were swollen and limiting the available vascular space. Functional studies revealed an increase in plasma urea nitrogen and creatinine after 1 hr or longer ischemic periods. The ischemia, cell swelling, "no-reflow," and subsequent renal dysfunction occurring after obstruction to the renal arteries were corrected by the administration of hypertonic mannitol, but were unaffected by an equivalent expansion of the extracellular fluid volume either with isotonic saline or isotonic mannitol, showing that the osmotic effect was primary. The hypothesis is presented that ischemic swelling of cells may occlude small blood vessels so that recirculation does not resume even after the initial cause of the ischemia is no longer present; solutes which do not penetrate cell membranes are able to shrink swollen cells, increase the available vascular space and thus permit reflow of blood to the ischemic organ.


Biosynthesis of vasopressin in vitro and ultrastructure of a bronchogenic carcinoma. Patient with the syndrome of inappropriate secretion of antidiuretic hormone. Tumors from patients with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) have been found to contain large amounts of the antidiuretic hormone vasopressin. A lung tumor from a patient with hyponatremia most likely due to SIADH was removed at surgery and found to contain 23.5 mU vasopressin/g wet weight by radioimmunoassay Slices of this tumor were incubated with phenylalanine-(3)H. Arginine vasopressin-(3)H was purified from the incubate by Sephadex G-25 column chromatography in two different systems, performic acid oxidation, and gradient elution column chromatography with diethylaminoethyl Sephadex. As oxidation of vasopressin results in drastic conformational change with breaking of the ring of the cyclic polypeptide and addition of two cysteic acid residues per molecule, the radioactive material which eluted coincident with vasopressin both before and after this procedure was considered to be arginine vasopressin-(3)H. To our knowledge this is the first demonstration of in vitro biosynthesis of vasopressin by a tumor from a patient with SIADH.Ultrastructurally, the bronchogenic carcinoma was composed of small undifferentiated and granulated cells. The granulated neoplastic cells had well developed organelles (endoplasmic reticulum, free ribosomes) concerned with protein synthesis. Secretion granules present in the tumor cells were small, surrounded by a limiting membrane, and resembled those reported in polypeptide hormone-secreting cells.


An evaluation of fetal renal function in a chronic sheep preparation. Fetal renal function in the sheep was investigated in a chronic preparation which permitted repeated evaluations of urine flow and osmolality as well as renal clearances in animals which were unanesthetized and remote from acute surgical stress. Measurements of fetal blood pressure, pH, osmolality, fetal growth in utero, and final outcome did not indicate an adverse effect of the experimental procedure on the fetus. Fetal urine flow and osmolality were highly variable during the early postoperative period. They did not stabilize until 3-6 days after surgery, when urine osmolality became markedly hypotonic (range 65-160 mOsm/kg H(2)O) and urine flow rose to approximately 0.14 ml/min.kg. Fluctuations in urine flow and osmolality in the early postoperative period were the result of tubular reabsorption of water rather than a change in the glomerular filtration rate. The inulin-(14)C clearance, used as a measure of the glomerular filtration rate, was 1.05 +/-0.05 ml/min.kg (mean +/-sem) for all animals studied. Urea, fructose, sodium, and chloride were partially reabsorbed by the fetal kidney, while creatinine was secreted. Continuous drainage of fetal urine for 18 days in one animal demonstrated that the fetus was able to excrete large amounts of water, sodium, and fructose without apparent detrimental effects.


Triiodothyronine radioimmunoassay.

Triiodothyronine radioimmunoassay. Highly specific antisera to triiodothyronine (T(3)) were prepared by immunization of rabbits with T(3)-bovine serum albumin conjugates. Antisera with T(3) binding capacity of up to 600 ng/ml were obtained. The ability of various thyronine derivatives to inhibit the binding of T(3-) (125)I to anti-T(3) serum was found to vary considerably. l-T(3), d-T(3) and several triiodoanalogues were potent inhibitors of the reaction. Little inhibition of T(3-) (125)I binding was produced by l-thyroxine (T(4)) or other tetraiodo- analogues, thyronine or iodotyrosines. Chromatography of several T(4) preparations indicated that most of their very slight activity could be ascribed to contamination with T(3). Successful assay of T(3) in serum was accomplished by the addition of diphenylhydantoin to the assay system. Under these circumstances, recovery of T(3) added to serum was excellent, and addition of T(4) was without significant effect. Serum T(3) concentrations in normal subjects averaged 145 +/-25 ng/100 ml (sd). Increased concentrations (429 +/-146 ng/100 ml) were observed in hyperthyroid patients whereas those with hypothyroidism had serum T(3) levels of 99 +/-24 ng/100 ml. Elevated T(3) concentrations were found also in hypothyroid patients receiving 25 mug or more of T(3) daily and in those receiving 300 mug of T(4) daily. Serial measurements of T(3) concentrations in subjects after oral T(3) administration revealed peak T(3) concentrations 2-4 hr after T(3) administration. Intramuscular administration of thyrotropin (TSH) resulted in earlier and more pronounced increases in serum T(3) than in serum T(4) concentrations. Triiodothyronine (T(3))(1) was recognized to be a biologically active secretory product of the thyroid gland over a decade ago (1). Recent studies have indicated that it is formed extrathyroidally as well (2, 3). Nevertheless, relatively little information concerning the role of T(3) secretion in different thyroid disorders has been accumulated until very recently. Methods for the measurement of T(3) which require its extraction from plasma, and often its separation from thyroxine as well, have been described by several investigators (4-11). These methods have proven useful, but they are relatively complicated, the number of samples that can be assayed is limited, and they may be affected by in vitro deiodination of thyroxine. More recently the radioimmunoassay technique has been applied to the measurement of T(3). Several preliminary reports have appeared describing the preparation of antibody to triiodothyronine by immunization of animals with T(3)-protein conjugates and its use for the measurement of T(3) in serum (12-15). The present report describes the development of a radioimmunoassay for the measurement of T(3), studies of the specificity of the anti-T(3) serum, and some initial studies which indicate that the method is applicable to the measurement of T(3) in unextracted serum.


Protein synthesis in intestinal mucosa: the effect of route of administration of precursor amino acids. All cells in the intestinal villus of the rat are capable of synthesizing protein from amino acid precursors (l-leucine). Moreover, polyribosomes from both crypts and villi are equally able to incorporate l-leucine into protein. Unlike other tissues, e.g. liver, there is no diurnal variation of protein synthesis in the intestine of the unfed rat, whether leucine is administered intraluminally or intravenously. The route of administration of precursor (l-leucine) is important in determining which part of the villus incorporates the label into protein. After intravenous administration, protein from cells near the villus-crypt junction is most heavily labeled, whereas after intraluminal administration protein from cells near the villus tip is most heavily labeled. The pattern of proteins most heavily labeled by radioactive precursor is different in the villus when compared with proteins from the crypt cells. Smaller molecular weight membrane-bound proteins are preferentially labeled in the crypt cells, whereas on the villus the pattern of labeling is more evenly distributed among the various proteins. Moreover, intraluminal leucine is utilized for protein synthesis to a greater extent than that in the blood, when the concentration in both compartments is similar. Thus, intraluminal and intravenous injections of labeled precursor are not equivalent. Both routes should be considered in data for experiments measuring intestinal protein synthesis.


Precursor-product relationship between pools of very low density lipoprotein triglyceride. The process of removal of triglyceride from the plasma may involve a sequential conversion of larger to smaller glyceride-rich lipoproteins. This has been studied within the species of lipoproteins comprising the very low density lipoproteins (VLDL) which transport the bulk of endogenously formed triglyceride. Palmitic acid-(14)C which was used to label the plasma glycerides was administered either as a prolonged constant infusion or as a pulse label. The specific activity-time curves of triglyceride fatty acids (TGFA) were analyzed both in total VLDL and in two subfractions of VLDL. The nature of the curves for total VLDL that were observed during the constant infusions were consistent with slow isotopic equilibration of precursors of VLDL-TGFA or with the presence of a precursor-product relationship between different components of VLDL-TGFA. The curves did not indicate any detectable differences in (fractional) turnover rates of independently metabolized pools of VLDL-TGFA. Differences in the specific activity-time curves of TGFA in two subfractions of VLDL (Sf > 100 and Sf 20-100) were consistent with a precursor-product relationship between TGFA in the two subfractions; again there was no indication of significant differences in (fractional) turnover rates. The specific activity-time curves of TGFA in the two subfractions of VLDL that were obtained with single injections of radio-palmitate showed a consistent difference in the rates at which TGFA became labeled in the two subfractions, being slower in the Sf 20-100 fraction. The findings from all experiments when considered together, were compatible with a precursor-product relationship that suggested that larger VLDL were converted to progressively smaller species as triglyceride was being removed.


Loss of membrane components in the pathogenesis of antibody-induced spherocytosis. The infusion of hyperimmune agglutinating antibodies into man or animals causes spherocytosis and hemolysis. The mechanism of spherocytosis was studied in rats given rabbit anti-rat red cell antiserum intravenously. During the 18 hr after antibody infusion, a time before the onset of reticulocytosis, hematocrits fell from 40.6 to 27.6%. However, no change occurred in mean cell volume, mean cell hemoglobin content, or the red cell concentrations of potassium or adenosine triphosphate (ATP). There was a progressive loss of membrane constituents and membrane surface area which followed first order kinetics. At 18 hr membrane cholesterol had decreased 23.5%, phospholipid 26.3%, protein 4.7%, and surface area (calculated from a measure of osmotic fragility) 14.2%. There was no change in the per cent composition of the various phospholipids. Similar changes occurred in animals splenectomized before receiving antibody.These studies demonstrate that spherocytosis induced by heterologous agglutinating antibodies in vivo results from a loss of surface area with no accompanying change in cell volume or in the concentration of the major intracellular constituents. It is caused by a process acting at the cell surface leading to the loss of lipid-rich, protein-poor components of the red cell membrane.


Effects of fasting and feeding on protein synthesis by the rat pancreas. These experiments were designed to determine whether fasting and feeding were associated with differing rates of protein synthesis in the rat pancreas. It has been established that feeding, acetylcholine, or cholecystokinin-pancreozymin administration was associated with enhanced rates of digestive enzyme secretion; however, the literature is unclear as to effects of such stimulation on enzyme synthesis. Rats fed ad lib. or fasted 24, 48, or 72 hr were used for this study. Pancreases were removed and incubated in tissue culture medium with l-phenylalanine-(14)C, and incorporation into TCA-insoluble material as well as purified amylase was measured. Compared with fed controls, fasting 24, 48, and 72 hr was associated with 29%, 39%, and 35% decreases in incorporation of l-phenylalanine-(14)C into protein. Decreases of similar magnitudes were apparent whether the data were expressed in terms of protein or DNA. Pancreatic amylase isolated from rats fasted 48 hr contained 57% fewer counts of l-phenylalanine-(14)C than amylase isolated from fed rats. Moreover, rats fasted for 24 hr and given bethanechol chloride incorporated greater amounts of l-phenylalanine-(14)C into protein than fasted controls. Studies were performed to exclude changes in pool size of precursor (l-phenylalanine-(14)C) or product (amylase) in accounting for decreases associated with fasting. These studies demonstrate that fasting was associated with decreased rates of pancreatic amylase and protein synthesis in rats.


Evaluation of venous bypass grafts from aorta to coronary artery by inert gas desaturation and direct flowmeter techniques. Blood flow through aorta-to-coronary artery bypass grafts has been measured selectively in 16 patients at or within 6 wk after operation. Inert gas desaturation curves were obtained from coronary venous blood samples after a 7-15 min infusion of dissolved H(2) directly into the graft. Samples were analyzed chromatographically and curves resolved to 1-3% of initial H(2) concentrations. Average flow per unit volume (F/V) was 67+/-21 (sd) ml/min per 100 g. Semilogarithmic plots showed F/V to be distributed heterogeneously in every case. In nine studies at operation, H(2) measurements of average F/V were combined with electromagnetic measurements of total flow to estimate revascularized tissue mass. Electromagnetic flows ranged from 25 to 170 ml/min and averaged 69 ml/min. Tissue mass ranged from 46 to 155 g and averaged 88 g. We conclude that bypass grafts provide nutritive flow to significant amounts of myocardium at and shortly after operation. However, nutritive flow is not distributed evenly throughout the revascularized segment. The majority of the segment has a F/V within the accepted range of normal but there remain areas in which F/V is reduced significantly. The combination of inert gas and electromagnetic techniques allows a revascularized area to be characterized in terms of total flow, F/V, and tissue mass.


Calcium release from the skeletons of rachitic puppies. The experiment was carried out on 3-month old puppies. Control animals received a diet normal in calcium and vitamin D. The diet for one group of experimental animals was deficient in both calcium and vitamin D, while another experimental group was fed a diet deficient in calcium but with adequate vitamin D. The response of these animals to injected parathyroid extract was evaluated over a 4 month period. The serum calcium response fell after approximately 20 days in both the calcium-deficient (vitamin D-replete) and the calcium- and vitamin D-deficient animals. The effect on the parathyroid response of the addition of calcium or vitamin D in vitamin D- and calcium-deficient animals was also evaluated. The addition of vitamin D to rachitic animals did not restore the response to parathyroid extract; however, in calcium- and vitamin D-deficient animals with normal calcium levels there was a restored response to parathyroid extract. Morphologic studies were made of the bone at various times during the experimental period; the presence of osteoid tissue correlated with the absence of a response to injected parathyroid extract. The results suggest that parathyroid hormone acts independently and requires the presence of mineralized bone for its action in raising the serum calcium. Vitamin D appears to be important in the mineralization of new bone tissue.


Vaccination against rubella.

Vaccination against rubella.


Scientific principles in design of drug dosage formulations.


Psychiatrists' attitudes to abortion.

Psychiatrists' attitudes to abortion.


Proprietary drugs.

Proprietary drugs.


Fibrin and cancer.

Fibrin and cancer.


Hospital Advisory Service.

Hospital Advisory Service.


Immune suppression, gliomas, and tuberculosis.


International convention on psychotropic drugs.


Camphorated oil.

Camphorated oil.


Pharmacologically active I.U.D.s.

Pharmacologically active I.U.D.s.


Phenformin overdose.

Phenformin overdose.


Sickle-cell trait and altitude.

Sickle-cell trait and altitude.


Prognosis of gastric cancer.

Prognosis of gastric cancer.


Transport to the surgery.

Transport to the surgery.


Erythema multiforme.

Erythema multiforme.


Occupational health service: beginning or end?


Clotting factor concentrates.

Clotting factor concentrates.


Problems of retinoblastoma.

Problems of retinoblastoma.


Writer's cramp.

Writer's cramp.


Bread iodine content and thyroid radioiodine uptake: a tale of two cities. The iodine content of bread consumed in the Bronx, New York, was found to be significantly lower than that of bread consumed in Columbia, Missouri. This difference in dietary intake of iodine could account for the lowered range of normal values for 24-hour (131)I uptake tests in Columbia, and the persistence of the same normal range for this test over the past 28 years in the Bronx. A population with high iodine intake requires higher doses of radioactive iodine in the diagnosis and treatment of thyroid disease. Questions are raised regarding the relationship of high iodine intake to the risk of developing thyrotoxicosis.


Menstrual blood loss and fibrin degradation products. As part of a large-scale study of menstrual blood loss in the community serum fibrin degradation products were measured soon after menstruation in 331 women. No significant correlation was found between the amount of blood lost and the serum level of fibrin degradation products. These findings conflict with reports suggesting that excessive intrauterine fibrinolysis, which may play a part in menorrhagia, is associated with raised serum F.D.P. concentrations.


Kidney function after methoxyflurane analgesia during labour. In a study of the effects of methoxyflurane on renal function, the urinary and blood urea concentrations, the urinary and plasma osmolalities, and the packed cell volume were studied in each of 50 mothers before and after delivery. Methoxyflurane 0.35% was used as an analgesic in 25 patients and the other 25 had 50% nitrous oxide and 50% oxygen (Entonox). There was no evidence of renal dysfunction in either group, nor were there any significant differences between the groups. In a further 200 mothers, of whom 100 had methoxyflurane and 100 had nitrous oxide analgesia, the urinary and blood urea concentrations were measured on the morning of discharge from hospital. There were no significant differences between the groups. These results suggest that methoxyflurane is not nephrotoxic when used as a self-administered analgesic.


Gynaecological illness after sterilization. A total of 374 patients were followed up for at least 10 years after tubal ligation, and 43% required further gynaecological treatment. Major gynaecological surgery was needed by 25%. There seems a good case for the selective use of hysterectomy as a method of sterilization.


Factitious hypoglycaemia: chlorpropamide self-administration by a non-diabetic.


Accidental gonococcal infection of the eyes in children.


Antiviral benzimidazoles. Direct 1-substitution of 2-(- -hydroxybenzyl)benzimidazole and related compounds.


Secondary mechanisms of antifungal action of substituted 8-quinolinols. 3. 5,7,8-Substituted quinolines.


Heterocyclic compounds. 4. Synthesis and antiinflammatory activity of some substituted thienopyrimidones.


Antitumor activity of 2,2-hydrazobis(3-chloro-1,4-naphthoquinone) against Walker 256(intramuscular) carcinosarcoma.


Anthelmintic 2-(5-nitro-2-thienyl)-4-(substituted amino)quinazolines.


Effects of S-(+)- and R-(-)-3,4,dimethoxyphenylisopropylamines in the rat.


4-amino--2-buten-1-ol esters.

4-amino--2-buten-1-ol esters.


Directional nature of hydrophobic bonding in phenethanolamine N-methyl transferase inhibitors.


N 1 ,N 1 -dialkyl-N 4 ,N 4 -dialkylaminoacetylsulfanilamide as potent surface anesthetics.


5-cyclohexyl-1-hydroxyacetylindans as potential antiinflammatory agents.


Synthesis of some 6-hydroxymethyluracil derivatives.


Structural modification of S-trityl-L-cysteine. Preparation of some S-(substituted trityl)-L-cysteines and dipeptides of S-trityl-L-cysteine.


Quantum mechanical study of the conformational properties of phenethylamines of biochemical and medicinal interest.


Phenethylamine in a rigid framework. 2,3-Substituted cis- and trans-6-amino-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ols.


Structure-activity relationship studies on antimalarial phenanthrene amino alcohols. Modification of the side chain.


Synthesis and biological activity of some 4-aryl-substituted 4-oxazolin-2-ones.


Derivatives of 4,5-dihydro-1,3,dimethyl-1H-pyrazolo(3,4-b)benzoxazepine with antiinflammatory activity.


Inhibitors of platelet aggregation. 3. ((Dialkylamino)alkyl)thio heterocyclic compounds.


Mixed bifunctionality. 4. Antitumor activity of alkylating derivatives of polycyclic aromatic hydrocarbons as a function of structure and of vehicle.


dl- -(4-Cycloaklyl(cyclohexen-1-yl)alkanoic acids and derivatives as antiinflammatory and antiarthritic compounds.


Aminobenzoic acid diuretics. 3. 4-Substituted 5-sulfamylanthranilic acid derivatives.


Preferred conformation of prostaglandin E 1 .


C-3-Oxygenation of 17 -methyl-5 -androstan-17 -ol by rabbit liver homogenate.


Synthesis and biological activity of D-bishomo steroids.


Cardiovascular activity of some substituted 2-aminobenzoquinolizines.


Inhibition studies on antibody to poly(L-tyrosyl-L-glutamyl-L-alanylglycyl)glycine-1- 14 C ethyl ester. Synthesis and immunochemical properties of poly(L-alanyl-L-glutamyl-L-alanylglycyl)glycine-1- 14 C ethyl ester.


Synthesis of the trail marker of the Texas leaf-cutting ant, Atta texana (Buckley).


Fibrin-stabilizing factor inhibitors. 4. Action of some synthetic fibrinoligase inhibitors on human platelet aggregation.


Effect of intestinal microflora on iron and zinc metabolism, and on activities of metalloenzymes in rats.


Studies on the fate of dietary linoleic acid in the neonatal rat.


Growth and food intake of rats fed tryptophan-imbalanced diets with or without niacin.


Dietary fat and hepatic citrate cleavage enzyme in growing chickens.


Site of phosphorus absorption from the intestine of the horse.


Nomenclature policy: generic descriptors and trivial names for vitamins and related compounds.


Methylmalonate, formiminoglutamate and aminoimidazolecarboxamide excretion of vitamin B 12 -deficient germfree and conventional rats.


Acid-base balance and sodium-to-chloride ratio in diets of laying hens.


Influence of amino acid level in the diet upon amino acid oxidation by the rat.


Influence of dietary protein on rat skeletal muscle growth.


Effect of protein deprivation of male weanling rats on the kinetics of hepatic microsomal enzyme activity.


Carcass amino acids of the rat under conditions of determination of net protein utilization.


Essential fatty acids in the diet of rainbow trout (Salmo gairdneri): growth, feed conversion and some gross deficiency symptoms.


Essential fatty acids in the diet of rainbow trout (Salmo gairdneri): physiological symptoms of EFA deficiency.


Essential fatty acids in the diet of rainbow trout (Salmo gairdneri): lipid metabolism and fatty acid composition.


Fiber digestion in the beaver.

Fiber digestion in the beaver.


Paroxysmal nocturnal hemoglobinuria. Hemolysis initiated by the C3 activator system.


Serum gastrin levels before and after vagotomy and pyloroplasty or vagotomy and antrectomy.


Radiation therapy in New Hampshire, Massachusetts and Rhode Island. Output and cost.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 4-1972.


Anticonvulsant therapy: to stop or not to stop.


Super or not-so-super selective vagotomy?


Localization of parathyroids by thermography.


Role of magnesium in myocardial function.


L-dopa and cardiac arrhythmia.

L-dopa and cardiac arrhythmia.


Bilateral "I. V. hydrothorax".

Bilateral "I. V. hydrothorax".


ECS elaborated.

ECS elaborated.


Sensitivity to chromium.

Sensitivity to chromium.


Shifts for hospital doctors.

Shifts for hospital doctors.


Registration of foreign medical graduates in Massachusetts.


Practitioners needed to define quality care.


Reinnervation after resection of the facial nerve.


The ancient art of memory. Usefulness in treatment.


Auditory neglect in man.

Auditory neglect in man.


Iodinated serum albumin dynamic cerebrospinal fluid flow studies. Pathological variations and positive and negative images.


Experimental cerebral microembolism. Multiple tracer assessment of brain edema.


An introductory experiment on phosphates in detergents.


Cerebral water and electrolytes. An experimental model of inappropriate secretion of antidiuretic hormone.


Removal of crude oil from marine surfaces. An ecological lecture experiment.


Air pollution measurements in the freshman laboratory.


Visualization of the atomic absorption of mercury vapor by use of a fluorescent screen.


Mercury poisoning. Illustrating competitive equilibria and role of similarities in molecular structure.


Identification of hazardous materials. IV. Toxic substances.


The medical treatment of dissecting aortic aneurysms.


Phagocytosis in chronic granulomatous disease and the Chediak-Higashi syndrome.


Assessing quality of care from the medical record.


Scanning electron microscopy of thrombogenesis on vascular catheter surfaces.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 3-1972.


Management of dissecting aneurysms of the aorta.


Oxidative hemolysis, or "what made the red cell break"?


Nature of tubular aggregates.

Nature of tubular aggregates.


Hepatitis in prisoner blood donors.

Hepatitis in prisoner blood donors.


INH prophylaxis.

INH prophylaxis.


Cataracts after short-term corticosteroid treatment.


Absorption of digoxin.

Absorption of digoxin.


Persistence of  125 I in thyroid.

Persistence of  125 I in thyroid.


Intoxicated enterocytes?

Intoxicated enterocytes?


Safety of disulfiram (antabuse).

Safety of disulfiram (antabuse).


Guanidine for botulism.

Guanidine for botulism.


Excessive fortification of flour with iron.


Histrionic teaching of history taking.

Histrionic teaching of history taking.


Beepless nights--and days.

Beepless nights--and days.


Systemic scleroderma and massive infarction of intestine and liver.


Effects of protein depletion on strength of colonic anastomoses.


Effects of heparin on wound healing.

Effects of heparin on wound healing.


Intraoperative relation of gastric secretion acidity and complete vagotomy.


Patterns of liver injury after fatal blunt trauma.


Carcinoma associated with pancreatic cyst.


The design and initial testing of an implantable infusion pump.


Fibromuscular disease of the carotid artery.


Intramyocardial gas tensions in the canine heart during anoxic cardiac arrest.


The role of intravascular coagulation in feline endotoxin shock.


Cephaloridine therapy in patients with surgical infections.


The effect of hepatic venous obstruction on the rate of flow of bile.


Splenectomy for trauma in childhood.

Splenectomy for trauma in childhood.


Mammography in its proper perspective.

Mammography in its proper perspective.


The surface fine structure of the walls of cerebral ventricles and of choroid plexus in cat.


Identification of blood meals of hematophagous arthropods by the hemoglobin crystallization method.


Probable filariasis in a Vietnam veteran.


Bancroftian filiariasis in two villages in Dinajpur District, East Pakistan. I. Infections in man.


Pentastomiasis in western Canada: a case report.


Two cases of myiasis in the United States by the African tumbu fly, Cordylobia anthropophaga (Diptera, Calliphoridae).


Ecologic studies of Venezuelan encephalitis virus in southeastern Mexico. VI. Infection of wild birds.


Ecologic studies of Venezuelan encephalitis virus in southeastern Mexico. VII. Infection of man.


Submentoplasty. Classification and theoretical outline of management.


Bone resorption under plastic chin implants. Follow-up of a preliminary report.


Double palatal pushback. A technique for correction of severe velopharyngeal insufficiency.


The surgical management of premaxillary malignancy. Report of three cases.


Endocrine exophthalmos. Concepts and surgical management.


Closed management of mandibular fractures.


Chemosurgery for facial neoplasms.

Chemosurgery for facial neoplasms.


The effect of heparin on thrombosis at microvenous anastomotic sites.


Correction of the traumatically abducted vocal cord.


Postlaryngectomy vocal rehabilitation.

Postlaryngectomy vocal rehabilitation.


Neck incisions relative to the cutaneous vasculature of the neck.


Tuning fork tests.

Tuning fork tests.


Conductive high-tone hearing loss.

Conductive high-tone hearing loss.


Some effects of involuntary eye movements.


Increment thresholds for two identical flashes.


Color matching and color-difference matching.


Visual assessment of the luminosity of daylight fluorescent pigments and its relationship with colorimetric quantities.


Effect of endotoxin on granulopoiesis and colony-stimulating factor.


Hypokalemic periodic paralysis with arrhythmia.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 5-1972.


The regulation of granulocyte production.


Why trust the professional?

Why trust the professional?


"Morning-after" contraception with stilbestrol.


Pliability of stenotic mitral valves.

Pliability of stenotic mitral valves.


Digoxin availability "like it is".

Digoxin availability "like it is".


Treatment of hyperuricemia and gout.

Treatment of hyperuricemia and gout.


Distribution of Australia antigen.

Distribution of Australia antigen.


Status of immunization of one-four year olds.


Reactions to adrenal venography.

Reactions to adrenal venography.


Amantadine in tardive dyskinesia.

Amantadine in tardive dyskinesia.


Aspirin: a new nightmare for blood bankers.


Sleep and depression.

Sleep and depression.


Effective medical mission in Vietnam.

Effective medical mission in Vietnam.


Hospital staff vs. administration.

Hospital staff vs. administration.


Poststreptococcal glomerulonephritis. A prospective study in children.


Left-superior-vena-cava steal syndrome.

Left-superior-vena-cava steal syndrome.


Complications of transtracheal aspiration.


Ceti.

Ceti.


Epidemiology of gastric cancer.

Epidemiology of gastric cancer.


Action of salicylates.

Action of salicylates.


Current status of rubella susceptibility testing.


Xanthinuria and hemochromatosis: follow-up.


Statistics of heroin addiction.

Statistics of heroin addiction.


Hiccup remedies.

Hiccup remedies.


In praise of exercise.

In praise of exercise.


Should pregnant teachers work?

Should pregnant teachers work?


Motorists vs. cyclists.

Motorists vs. cyclists.


Mechanical equilibrium of biological membranes. The nature of mechanical and electrical forces on biological membranes in relation to mechanical equilibrium is examined. The presence of a double layer of electric charge is shown to give rise to an effective pressure drop across a curved membrane of finite thickness. For certain geometric shapes of a membrane, the magnitude of the pressure drop due to electrostatic forces may set a limit on the hydrostatic pressure drop that the membrane can support without buckling. The results are applied to the equilibrium shape of the red blood cell.


Cable theory for finite length dendritic cylinders with initial and boundary conditions. The cable equation is solved in the Laplace transform domain for arbitrary initial and boundary conditions. The cable potential is expressed directly in terms of the impedance of the terminations and the cable electrotonic length. A computer program is given to invert the transform. Numerical solutions may be obtained for any particular model by inserting expressions describing the terminations and parameter values into the program, without further computation by the modeler. For a finite length cable, sealed at one end, the solution is expressed in terms of the ratio of the termination impedance to the impedance of the finite length cable, a generalization of the steady-state conductance ratio. Analysis of a model of a soma with several primary dendrites shows that the dendrites may be lumped into one equivalent cylinder if they have the same electrotonic length, even though they may vary in diameter. Responses obtained under voltage clamp are conceptually predictable from measurements made under current clamp, and vice versa. The equalizing time constants of an infinite series expression of the solution are the negative reciprocals of the roots of the characteristic equation. Examination of computed solutions shows that solutions which differ theoretically may be indistinguishable experimentally.


Synergistic inactivation of viruses by heat and ionizing radiation. Viral inactivation by heat and/or ionizing radiation is analyzed in terms of a kinetic model. The phenomenon of synergistic viral inactivation observed when viruses are exposed to the simultaneous application of heat and ionizing radiation is interpreted within the framework provided by this three-term model. Data on the inactivation of T4 bacteriophage by heat and/or ionizing radiation is presented, and the kinetic model is used to provide a description of observed dose rate and temperature dependences. Extension of the model to other viral systems inactivated by heat and ionizing radiation is considered, and the general applicability of these analyses suggests that the kinetic model may well serve as an extension of target theory in describing the radiobiological effects of ionizing radiation.


19 F nuclear magnetic resonance for the control of peptide synthesis.


Stereochemical basis of anticonvulsant drug action. II. Molecular structure of diazepam.


The detection of intermediates during the conversion of propane-1,2-diol to propionaldehyde by glyceroldehydrase, a coenzyme B 12  dependent reaction.


Mechanism of the  -chymotrypsin-catalyzed hydrolysis of specific amide substrates.


Helix sense of poly- -benzyl-L-aspartate.


Valinomycin-cation complex. Conformational energy aspects.


Crystal structure and conformation of the cyclic dipeptide cyclo-L-prolyl-L-leucyl.


The challenge ahead.

The challenge ahead.


New dimensions for dietetics in today's health care.


The changing role of the service professional within the ghetto.


Nutrition and pregnancy.

Nutrition and pregnancy.


Growth of preschool children in the North Central Region.


Sophomore high school students' attitudes toward school lunch.


The health care delivery system of tomorrow.


Drug standards laboratory enters second decade.


Drug product equivalence--are specifications necessary?


Drug product equivalence--the problem, the challenge and the USP.


'Future shock' and the pharmacy student.


Dynamic characteristics of retinal ganglion cell responses in goldfish. A cross-correlation technique has been applied to quantify the dependence of the dynamic characteristics of retinal ganglion cell responses in goldfish on intensity, wavelength, spatial configuration, and spot size. Both theoretical and experimental evidence justify the use of the cross-correlation procedure which allows the completion of rather extensive measurements in a relatively short time. The findings indicate the following. (a) The shape of the amplitude characteristics depends on the energy per unit of time (power) falling within the center of a receptive field rather than on the intensity of the stimulus spot. For spot diameters of up to 1 mm, identical amplitude characteristics can be obtained by interchanging area and intensity. Therefore the receptor processes do not contribute to the change in the amplitude characteristics as a function of the power of the stimulus light. (b) For high frequencies the amplitude characteristics obtained as a function of power join together in a common envelope if plotted on an absolute sensitivity scale. For spontaneous ganglion cells this envelope holds over a range of three log units and the shape is identical for central and peripheral processes. (c) The amplitude characteristics of the central and peripheral processes converging to a ganglion cell are identical, irrespective of the sign (on or off) and the spectral coding of the response. Therefore we have no evidence for interneurons in the goldfish retina unique to the periphery of the receptive field.


The influence of hydrogen ion concentration on calcium binding and release by skeletal muscle sarcoplasmic reticulum. Calcium release and binding produced by alterations in pH were investigated in isolated sarcoplasmic reticulum (SR) from skeletal muscle. When the pH was abruptly increased from 6.46 to 7.82, after calcium loading for 30 sec, 80-90 nanomoles (nmole) of calcium/mg protein were released. When the pH was abruptly decreased from 7.56 to 6.46, after calcium loading for 30 sec, 25-30 nmole of calcium/mg protein were rebound. The calcium release process was shown to be a function of pH change: 57 nmole of calcium were released per 1 pH unit change per mg protein. The amount of adenosine triphosphate (ATP) bound to the SR was not altered by the pH changes. The release phenomenon was not due to alteration of ATP concentration by the increased pH. Native actomyosin was combined with SR in order to study the effectiveness of calcium release from the SR by pH change in inducing super-precipitation of actomyosin. It was found that SR, in an amount high enough to inhibit superprecipitation at pH 6.5, did not prevent the process when the pH was suddenly increased to 7.3, indicating that the affinity of SR for calcium depends specifically on pH. These data suggest the possible participation of hydrogen ion concentration in excitation-contraction coupling.


Ionic channels and nerve membrane constituents. Tetrodotoxin-like interaction of saxitoxin with cholesterol monolayers. Saxitoxin (STX) and tetrodotoxin (TTX) have the same striking property of blocking the Na(+) channels in the axolemma. Experiments with nerve plasma membrane components of the squid Dosidicus gigas have shown that TTX interacts with cholesterol monolayers. Similar experiments were carried out with STX. The effect of STX on the surface pressure-area diagrams of lipid monolayers and on the fluorescence emission spectra of sonicated nerve membranes was studied. The results indicate a TTX-like interaction of STX with cholesterol monolayers. The expansion of the monolayers caused by 10(-6)M STX was 2.2 A(2)/cholesterol molecule at 25 degrees C. From surface pressure measurements at constant cholesterol area (39 A(2)/molecule) in media with various STX concentrations, it was calculated that the STX/cholesterol surface concentration ratio is 0.54. The apparent dissociation constant of the STX-cholesterol monolayer complex is 4.0 x 10(-7)M. The STX/cholesterol ratio and the apparent dissociation constant are similar to those determined for TTX. The presence of other lipids in the monolayers affects the STX-cholesterol association. The interactions of STX and TTX with cholesterol monolayers suggest (a) that cholesterol molecules may be part of the nerve membrane Na(+) channels, or (b) that the toxin receptor at the nerve membrane shares similar chemical features with the cholesterol monolayers.


Biophysical effects of adrenaline on the smooth muscle of the rabbit common carotid artery. Effects of adrenaline on the smooth muscle of the rabbit common carotid artery were studied by the partitional chamber method. The experiments on excitation-contraction coupling were carried out in isotonic Krebs solution; the other experiments were carried out in hypertonic Krebs solution. Adrenaline (10(-7) g/ml) caused rhythmical electrical and mechanical activity of arterial strips in isotonic Krebs solution. By addition of adrenaline (10(-5) g/ml), the membrane was depolarized by about 10 mv and the amplitude of the electrotonic potential was decreased by 40-50% of the control in hypertonic Krebs solution. Present experimental results suggest that the depolarization of the membrane and the decrease of the amplitude of the electrotonic potential in the artery are due to the increase of Na and Cl conductance. Contraction appeared in all preparations exposed to 10(-8) g/ml adrenaline; at that concentration membrane potential and membrane resistance showed little or no change.


Craniopharyngioma originating in the sphenoid bone. Case report.


Meningiomas of the sphenoidal ridge.

Meningiomas of the sphenoidal ridge.


Acute spinal cord compression paralysis.


The permeability of capillaries of the sciatic nerve of the rabbit to several materials.


Subarachnoid hemorrhage in pregnancy.

Subarachnoid hemorrhage in pregnancy.


Progressive ventricular dilatation following pneumonencephalography. A radiological sign of occult hydrocephalus.


Experimental evaluation of a tissue adhesive as an agent for the treatment of aneurysms and arteriovenous anomalies.


Sudden blindness with pituitary tumors. Report of three cases.


Ureteral injury incident to lumbar disc surgery. Case report.


Multiple primary tumors of the brain and bowel. Case report.


The value of preoperative angiography in the surgical management of cervical hourglass neurofibroma. Case report.


Cholesterol 26-hydroperoxide.

Cholesterol 26-hydroperoxide.


A novel protecting group for the synthesis of 7 -D-pentofuranosylhypoxanthines.


Model studies of the synthesis of echitamine and related indole alkaloids.


Reduction of 6 -methoxy-3 ,5-cyclo-5  steroids with mixed hydrides.


Meningococcal pericarditis. Report of 2 cases, 1 complicated by acute constrictive pericarditis.


Extralobar pulmonary sequestration. Presentation as an arteriovenous aneurysm with cardiac failure in infancy.


Hypersensitive carotid sinus syncope treated by implantable demand cardiac pacemaker.


A critical appraisal of ballistocardiography.


Ventricular aneurysm. A clinical--pathologic correlation.


Myocardial anaerobiosis in anemia in uremic man.


The relation between myocardial  3 H-digoxin concentration and its hemodynamic effects.


Peritoneal dialysis for intractable heart failure in acute myocardial infarction.


Collateral vessel development after right ventricular infarction in the pig.


Coexisting left anterior hemiblock and inferior wall myocardial infarction. Vectorcardiographic features.


Mitral valvular abnormalities associated with supravalvular aortic stenosis. Observations in 3 cases.


Malfunction of mitral ball valve prosthesis due to thrombus. Report of 2 cases with notes on early clinical diagnosis.


Carcinoma of the common bile duct. Report of a case of successful resection.


Control of massive hemorrhage from vena cava and liver injuries. A simplified technique.


Benign gastric ulcer as a cause of gastrocolic fistula. Report of a case and review of the literature.


Compression of the brain and spinal cord following use of gelfoam.


Posterior hernial repair and prostatic operations.


Will it happen again?

Will it happen again?


Corrugated arteries. Fixed pathology or functional alteration?


Gait characteristics of the rheumatoid knee.


Retrosternal dislocation of the clavicle.


Midline extraperitoneal approach for bilateral inguinofemoral hernias and prostatic obstruction. A study of 37 cases.


Lung perfusion scanning for estimation of postoperative pulmonary function.


Plasma elastolytic enzyme activity in pancreatic disease.


Elastase activity in pancreatic juice and plasma of the dog.


Compensatory hypertrophy of the gut. Testing of the tissue mass, intraluminal nutrition and functional demand hypothesis.


The small intestine and gastric secretion in the rat. The effects of intestinal bypass, resection, and supplemental hydration on interdigestive gastric secretion.


Effect of diphenhydramine on glycine-preduced hyperammonemia in dogs.


Pulmonary hemodynamics following injection of denatured globin hemochromogen.


Visceral pleural patch for support of esophageal anastomosis.


Minor cerebral ischemia from major brachiocephalic occlusion.


The role of heparin in the management of consumption coagulopathy.


Hemorrhagic diathesis induced by surreptitious ingestion of coumarin drugs.


Detection of diabetes mellitus: a community study.


Community attitudes toward alcoholics: implications for public policy.


Present status of the secretin test.

Present status of the secretin test.


The white psychiatrist vs the black patient. Are blacks being whitewashed?


Status of adrenalectomy in the treatment of metastatic breast cancer. A review of 84 patients.


Radiologic problem case.

Radiologic problem case.


Central pit of the optic disk.

Central pit of the optic disk.


The weakening surgical procedures for eliminating overaction of the inferior oblique muscle.


Cryoextraction adhesion parameters.

Cryoextraction adhesion parameters.


Retinopathy of sarcoidosis.

Retinopathy of sarcoidosis.


Direct physical demonstration of oily layer on tear film surface.


Clinical pharmacologists in ophthalmology.


Surgical treatment for Elschnig's pearls.


Cataract extraction in the retinal detachment-prone patient.


A new concept for vitreous surgery. I. Instrumentation.


Cellular immunity in chronic ophthalmic disorders. 3. Leukocyte migration inhibition in uveitis.


Ocular manifestations of the diencephalic syndrome.


Reconstruction of the anterior segment of an eye by autotransplantation of the posterior segment of the fellow eye.


Calcium and hypo-allergenic diets.

Calcium and hypo-allergenic diets.


Cholesterol 26-hydroperoxide.

Cholesterol 26-hydroperoxide.


The configuration of D-alanyl-D-cycloserine confirmed.


Synthesis of polyglutathione, polyasparthione, and related sequential polypeptides.


Reduction of 6 -methoxy-3 -cyclo-5  steroids with mixed hydrides.


A novel protecting group for the synthesis of 7 -D-pentofuranosylhypoxanthines.


A synthesis of 4-azaoxindole.

A synthesis of 4-azaoxindole.


Structure-activity relationship in the chymotrypsin hydrolysis of p-nitrophenyl esters.


Cigarette smoking and arteriosclerosis obliterans: an epidemiologic approach.


Birthweight and the displacement hypothesis.


Atherosclerosis in the Masai.

Atherosclerosis in the Masai.


Uses of the surname in epidemiologic research.


Radiation exposure in utero and mortality.


Infectious mononucleosis in a general population.


The Philadelphia pulmonary neoplasm research project: basic risk factors of lung cancer in older men.


Further studies on the natural host preferences of Panamanian phlebotomine sandflies.


Integrated actions of the four heads of quadriceps femoris: an electromyographic study.


Adjustment of the myelin sheath to changes in axon caliber.


Role of chondrocytes and hydrocortisone in resorption of proximal fragment of Meckel's cartilage: an in vitro and in vivo study.


Fine structure of a fifth type of epithelial cell in the thyroid gland of the C 3 H mouse.


Effects of x-irradiation on lens regeneration in adult Triturus viridescens.


A radiographic and histologic study of bone in the active and hibernating bat (Myotis lucifugus).


Fine structure of sinusoids and portal capillaries in the liver of the adult sheep and the newborn lamb.


Mesonephric adenocarcinomas of the cervix.


Cancer colli uteri and pregnancy.

Cancer colli uteri and pregnancy.


Ultrastructure of hemangioendothelial sarcoma of bone.


Lipomatosis of the ileocecal valve.

Lipomatosis of the ileocecal valve.


Meningiomas presenting as nasal polyps.

Meningiomas presenting as nasal polyps.


Zone-electrophoretic pattern of proteins in the cystic fluid of ovarian tumors.


Effect of pluronic-F68 on the development of tumor metastasis.


Advanced ovarian cancer: primary treatment with surgery, radiotherapy, and chemotherapy.


Gastritis cystica polyposa. (Gastric mucosal prolapse at gastroenterostomy site, with cystic and infiltrative epithelial hyperplasia).


Renal carcinoma in mother and daughter.

Renal carcinoma in mother and daughter.


Basal cell adenoma of the parotid gland.


Evolution of neck disease in patients with primary squamous cell carcinoma of the oral tongue, floor of mouth, and palatine arch, and clinically positive neck nodes neither fixed nor bilateral.


Bacteroides bacteremia. Experience in a hospital for neoplastic diseases.


Occurrence and prognosis of extranodal lymphomas.


Evaluation of the mode of cell death in Ehrlich ascites tumor.


Cancer of the vocal cord.

Cancer of the vocal cord.


Contribution of diagnostic laparotomy to staging non-Hodgkin's lymphoma.


Role of laparotomy and splenectomy in the management of Hodgkin's disease.


Fibrosarcoma occurring at the site of a plastic vascular graft.


Primary fibrosarcoma of aorta.

Primary fibrosarcoma of aorta.


Carcinoma of the urinary bladder. (Comparison with radical, simple, and partial cystectomy and intravesical formalin.


[Blood picture determination using ear-lobe or finger-pad blood].


A telephone and walk-in emergency service in a state hospital.


A comparison of symptom evaluations by psychiatrists and social workers.


The development of a graduate program in psychiatry.


An operant-conditioning program for severely and profoundly retarded adults.


Mental health, national health insurance, and the economy.


Patterns of staff development.

Patterns of staff development.


Keeping PM&R effective in a rapidly changing hospital.


The psychopathic code and the therapeutic community.


Training the mental health assistant to communicate with schizophrenic patients.


Future changes in mental health care.

Future changes in mental health care.


"Jiffy stage" makes learning exciting.

"Jiffy stage" makes learning exciting.


Of doubters and zealots.

Of doubters and zealots.


Patients employed as aide assistants.

Patients employed as aide assistants.


New work shift expands treatment hours.

New work shift expands treatment hours.


A swing of the pendulum.

A swing of the pendulum.


The relationship of the national concern for the environment to the ecology of the academic community.


The responsibility of the campus to the community.


The university, the community and environmental health.


The development of an environmental health and safety program in a comprehensive health program for the campus community.


Campus wastes--a community problem.

Campus wastes--a community problem.


A campus teams up for safety.

A campus teams up for safety.


Fire safety design in high-rise campus buildings.


Contamination by mercury in chemical laboratories.


Nurse practitioner in-service training program.


A survey of attitudes of students toward utilization of the university health center.


Biographical and clinical variables related to frequent versus infrequent visits by students to a university counseling and mental health service.


Enteritis secondary to Giardia lamblia in students traveling on tour in Russia.


Bronchial epithelium in cigarette-smoking college students.


A longitudinal study of nonmedical drug use among university students--a brief summary.


The effects on student utilization of moving an on-campus health center off campus.


A study of some students' opinions and knowledge of smoking and drinking.


The application of computer technology to health programs.


Proposed guidelines for tuberculosis control in colleges.


Cryothalamectomy in parkinsonism. Effects on critical flicker frequency.


Pleasure and brain activity in man. Deep and surface electroencephalograms during orgasm.


Lithium excretion and therapeutic response.


Distinctiveness of maternal control. A further link in a theory of schizophrenic development.


A case of atypical Kleine-Levin syndrome: 30 years' observation.


Transitions in mesophase-forming systems. 3. Transformation kinetics and textural changes in cholesteryl nonanoate.


Effect of hypocholesteremic drugs on tumor-bearing mice.


Interrelationships of renal hemodynamics, intrarenal pressures and renal lymph formation.


The effect of dissolved oxygen partial pressure on growth, metabolism and immunoglobulin production in a permanent human lymphocyte cell line culture.


Interferon induction by Colorado tick fever virus: a double-stranded RNA virus.


Phosphattidyl cholines of aorta from rabbits fed cholesterol.


Effects of platelet transfusions: plug formation and maintenance of vascular integrity.


Effect of urease injections on Ehrlich ascites tumor growth in mice.


Biochemical and morphological aspects of mitochondrial swelling in ammonia toxicity.


Blood glucose and free fatty acid (FFA) responses to catecholamines in rats treated chronically with noradrenaline or adrenaline.


Longevity and mortality distributions of mice with and without x-ray exposure to 45 generations of male progenitors.


Disappearance of exogenous erythropoietin (ESF) from the blood of germfree mice.


The effect of acetylcholine on single embryonic chick ventricle cells.


Incorporation of S-(9-hydroxy-9,10-dihydro-10-phenanthryl)-L-cysteine into rabbit hemoglobin.


The effect of estrogen and progesterone on genital tract weight and glycogen content in ovariectomized guinea pigs.


Relation of porphyrin content to red cell age: analysis by fractional hemolysis.


Sodium flux into the renal tubular lumen during saline loading.


Virucidal properties of light and SO 2 . I. Effect on aerosolized Venezuelan equine encephalomyelitis virus.


Glucose oxidation in isoproterenol-stimulated salivary glands of the rat.


Thymolytic and adrenal cortical responses to the LDH-elevating virus.


Antagonism of erythropoietin production in rabbits by atropine.


Diuretic action of secretin in dog.

Diuretic action of secretin in dog.


The age-dependent response of serum triglycerides to dietary fructose.


2,3,5,6-tetrachloro-4-pyridinol: a new chemical structure for anticoagulant activity.


Intracellular fluoride in cultured mammalian cells.


Effects of pentobarbital on plasma glucose and free fatty acids in the rat.


Immune response to intracellular parasites: suppression by antibody.


Accentuation of production of human interferon by metabolic inhibitors.


The analysis and fractionation of LH 125 I by gel filtration.


Enhancement and suppression of murine sarcoma virus induced tumors by polyriboinosinic-polyribocytidylic acid.


Mitosis and DNA synthesis in mouse kidney: sources of error in evaluating cell proliferation.


Antiarthritic and antiinflammatory effects of certain prostaglandins.


Effect of aflatoxin on complement activity in guinea pigs.


Effect of inotropic agents on distensibility of the isolated cat heart.


Differences between serum and plasma osmolalities and their relationship to lactic acid values.


Regulation of superficial single nephron glomerular filtration rates in infant rats.


Potentiation, by nicotine, of duodenal ulcers in the rat.


Growth of the beagle: changes in the body fluid compartments.


Modified acute canine viral hepatitis--a model for physiologic study.


Evidence that a plasma factor(s) stimulates H+ and NH4+ excretion in the toad urinary bladder.


The effects of parathyroid extract upon incorporation of 1- 14 C-glucosamine into bone.


Effect of dietary calcium and phosphorus on  54 Mn metabolism following single tracer intraperitoneal and oral doses in rats.


Erythropoietic response to hemolytic and hemorrhagic anemia.


Suckling mouse cataract agent (SMCA)-induced hydrocephalus and chronic brain infection in newborn rats.


Preferential retention of taurine-conjugated bile salts by cholestyramine in the rat ileum.


Correlation between  47 Ca absorption and intestinal calcium-binding activity in the golden hamster.


The effects of guanidinosuccinic acid and methylguanidine on erythrocyte cation transport.


Human chorionic gonadotropin binding to rat ovarian tissue in vitro.


Retinal atrophy and cataract in rats following administration of N-methyl-N-nitrosourea.


Decreased interferon response to polyinosinic-polycytidylic acid in rabbits immunized against the inducer.


Spontaneous remission: fact or artifact?


A serum substitute for mammalian cells in culture. I. Biological efficacy of whole and fractionated peptone dialysate.


Early infantile autism: a reply to Ward.


Comment on Ward's "early infantile autism".


Nuclear membrane contributions to the Golgi complex.


Resorption of horseradish peroxidase from the middle ear cavity of guinea pigs.


Pyometra with massive foam cell reaction: a case report.


Fetal responses to maternal exercise in the sheep.


Open legal abortion "on request" is working in New York City, but is it the answer?


Differential reactivity of the myoendometrial and placental vasculatures: adrenergic responses.


Time of ovulation and prolonged pregnancy.


Supervision of high-risk cases by amnioscopy.


Monozygotic twins with the Turner syndrome.


The effects of continuous paracervical block, with one per cent lidocaine, on the fetal heart rate and uterine contractions.


A colorimetric method for amniotic fluid phospholipids and their relationship to the respiratory distress syndrome.


Corynebacterium vaginale vaginitis. Review of the literature and presentation of data based on vaginal cultures from 1,008 patients. A partial review of past investigations concerning vaginitis associated with Corynebacterium vaginale (formerly known as Haemophilus vaginalis) includes therapy, laboratory diagnosis and taxonomy.  An investigation involving 1008 patients during a 6 week postpartum period evaluated several hypotheses.  It was found that the incidence of positive cultures was greater in nonpregnant patients with vaginitis when compared with the whole population; the positive culture rate was s ignificantly higher in patients with vaginitis than without (p .  001); th e incidence of positive cultures between women using oral contraceptives (OC) or women using IUDs and the population at large was the same; and p ositive cultures were similar in patients using IUDs as in those using n o  contraceptives.  This study demonstrated that C-vaginale is a vaginal pathogen which is not influenced by OC and IUD use.  The means of therapy need further evaluation.


Ultrastructure of the Brenner tumor.

Ultrastructure of the Brenner tumor.


An analysis of statistical methods for comparing obstetric outcomes: infant health in three samples of school-age pregnancies.


Utilization is the name of the game in the surgical suite.


The law in the O.R.--is the surgeon the captain of the ship?


Ontario streamlines the operation of its hospital insurance commission.


What is the accreditation surveyor looking for in the operating room?


Block booking in the O.R.--a solution to a multitude of sins.


The organization and delivery of health care.


A doctor's role in controlling hospital costs.


The laundry industry reviewed.

The laundry industry reviewed.