Late somatic effects in rats treated with 2- -aminoethylisothiouronium-Br-HBr and exposed or not to X-irradiation.


Influence of a radioprotective substance AET-BrHBr (aminoethylisothiuronium-BrHBr) upon the survival half-time of erythrocytes labeled with  51 Cr in whole-body X-irradiated rats.


The College of Physicians of Philadelphia. Annual reports, 1970.


The doctor shortage: a contrived issue.

The doctor shortage: a contrived issue.


[Cerebellar sarcoma in an infant with atypical course].


Report of a survey of the group medical clinics serving beneficiaries of the United Mine Workers Welfare and Retirement Fund in the Pittsburgh area.


Organization and quality of service in a national health program.


Functional group practice in a national health program.


The relevance of international studies for design of a U.S. national health program.


Personal health services--as defined and organized by E. Richard Weinerman, M.D.


Community and minority group relations.

Community and minority group relations.


Medicine and community: innovations at Yale-New Haven Medical Center to meet the challenges.


Drug abuse and personality in young offenders.


Studies on the Masai.

Studies on the Masai.


Effect of controlled breakfast on serum cholesterol and triglycerides.


Correlation between body volume and body mass in men.


Absorption and metabolism of D(--) fructose in man.


Effect of chromium on glucose utilization in marasmic protein-calorie malnutrition.


Response of tropical sprue to poorly absorbed sulfonamides and oxytetracycline.


Experience with an appetizing, high protein, low folate diet in man.


A curriculum for the nutrition programmer.


Role of a dietary goitrogen in the etiology of endemic goiter on Idjw Island.


Experimental designs in investigations of mechanical properties in biological tissues.


Molecular weight studies on concanavalin A.


Studies on protocollagen: identification of a precursor of proto alpha 1.


Synthesis and interactions of cytoplasmic membranes in the pancreatic exocrine cells.


On the type of linkage binding fatty acids present in brain white matter proteolipid apoprotein.


Anomalous sedimentation of high molecular weight denatured mammalian DNA.


Origin of mitochondrial enzymes. IV. On the character of the product of cytochrome c synthesis by the endoplasmic reticulum.


Hypoglycemic action of 2-aminonorbornane-2-carboxylic acid in the rat.


ATP inhibition of aminolevulinate (ALA) synthetase activity in Rhodopseudomonas spheroides Y.


Stereoselective hydrolysis of cis- and trans-stilbene oxides by hepatic microsomal epoxide hydrolase.


NMR studies of organic solvent denatured yeast phenylalanyl transfer RNA at 220 MHZ a.


Interaction of ethidium with the mitochondrial membrane: cooperative binding and energy-linked changes.


Separation and characterization of the inhibitory factor of the troponin system.


Cytoplamic synthesis of acidic chromosomal proteins.


Reaction of 2-hydroxy-5-nitrobenzylated carboxypeptidase A with  14 C-1-fluoro-2,4-dinitrobenzene.


Species of RNA extracted from tobacco and Datura plants and their differential sensitivity to actinomycin D.


Electrophoretic variants of hemoglobin in the California ground squirrel, Spermophilus beecheyi beecheyi (Richardson).


Temperature-dependent actinomycin D effect on RNA synthesis during synchronous development in Neurospora crassa.


Micro-scale peptide mapping method for identification of variant proteins.


Identification of HeLa cell glucose 6-phosphate dehydrogenase.


In vitro mitochondrial complementation in Neurospora crassa.


Evidence for linkage between glucose 6-phosphate dehydrogenase and hypoxanthine-guanine-phosphoribosyl transferase loci in Chinese hamster cells.


The metabolism of trimethylamine N-oxide by Bacillus PM6.


Distribution and characterization of hexose 6-phosphate dehydrogenase in trout.


Configurational dependencies of (19F) fluorine chemical shifts and coupling constants in fluoromonosaccharides.


Phosphorylated penolic glucosides in higher plants.


Some quantitative aspects of the labelling of proteins with  125 I by the iodine monochloride method. The labelling of proteins by the iodine monochloride method was studied by using a mathematical model. The equations used were primarily derived from the mass law equation of the isotopic exchange reaction between [(125)I]iodide and iodine monochloride. For convenient application, all equations were programmed into a computing desk-top calculator. To support the validity of the theoretical model, a series of iodinations of insulin were performed under various labelling conditions. The results of these experiments compare well with the theoretically derived values. Deviations from the theoretical values occurring at molar ratios of [(125)I]iodide to iodine monochloride < 0.1 and > 4.0 are explained and suggestions made about how to prevent them. The mathematical model was used to simulate the isotopic exchange, and the iodination reaction under various conditions, to study (a) the influence of the amount of [(125)I]iodide on the amount of [(125)I]iodine monochloride formed, (b) the influence of the specific radioactivity of [(125)I]iodide on the amount of [(125)I]iodine monochloride formed, and (c) the influence of the specific radioactivity of [(125)I]iodide on the number of millicuries needed for labelling to a desired extent.


Aggregated states of mitochondrial structural protein.


Acetoacetate as a fuel for perfused rat skeletal muscle.


Activity of ketone-body utilization pathway in brain of suckling and adult rats.


Metabolic effects of propionate administration to normal and vitamin B12-deficient rats.


Uptake of ketone bodies by rat brain in vivo.


The metabolism of homoanisic acid in man and guinea pigs.


End-product inhibition of aspartate carbamoyltransferase from wheat germ.


On-line computing in the ambience of the Edinburgh multi-access project.


Prenol phosphates and mannosyltransferases.


Shared real-time access to a small computer.


Rat liver mitochondrial monoamine oxidase, a flavin-containing enzyme.


The kinetic properties of human placental choline acetyltransferase.


The effect of Trypan Blue, suramin and aurothiomalate on the breakdown of  125 I-labelled albumin within rat liver lysosomes. 1. A fraction enriched in lysosomes was prepared by centrifugation from the livers of rats that had been injected 0.5h before death with (125)I-labelled albumin. When suspended in sucrose-protected buffer, pH7.4, and incubated at 22 degrees C for 2h, the particles progressively released iodotyrosine into the medium. Albumin digestion did not occur if the particles were subjected to treatments known to break lysosomes or if particles from uninjected rats were incubated in medium containing (125)I-labelled albumin. It is concluded that the observed production of iodotyrosine results from protein hydrolysis within intact heterolysosomes. 2. Particles from rats pre-treated with Trypan Blue, suramin or aurothiomalate released iodotyrosine more slowly than controls. Since these compounds are enzyme inhibitors that concentrate in liver lysosomes after administration in vivo, their effect is ascribed to intralysosomal inhibition of proteolysis. The doses used did not decrease endocytosis of albumin into liver or cause increased lysosome breakage during incubation, thus allowing some alternative explanations of the decreased proteolysis to be eliminated. Particulate carbon, a non-inhibitor that also concentrates in lysosomes, did not affect albumin hydrolysis.


Effect of vitamin A status on the content of some steroids in the ovarian-vein blood of pregnant rats.


Subcellular protein movement in rat uterus and liver.


Enzyme changes indicative of fibre type in the denervated rat hemidiaphragm.


Induction of delta-aminolaevulate synthetase activity in cultured chick-embryo liver cells by ribonucleic acid.


Proteolipid metabolism in denervated muscle.


Binding of polylysine and Toluidine Blue to deoxyribonucleoprotein.


Investigations into the nucleotide sequence of cysteine transfer ribonucleic acid from baker's yeast.


Tyrosine metabolism in the blowfly larva, Calliphora erythrocephala.


Species differences in the formation of 4-amino-3-biphenylyl beta-D-glucosiduronate in vitro.


Computer assistance in the chemical pathology laboratory.


Small versus big computers for data processing.


Molecular modelling and computer graphics.


On-line applications in x-ray crystallography.


Computer control of mechanical experiments on muscle.


Molecular aspects of the regulation of rat kidney alkaline phosphatase. The mechanisms by which phosphate regulates the activity of alkaline phosphatase (orthophosphoric monoester phosphohydrolase, EC 3.1.3.1) in rat kidney were investigated. Measurements of incorporation of [(14)C]leucine into kidney alkaline phosphatase in rats fed on complete or phosphate-free diet provide evidence of a twofold increase in the rate of synthesis of the enzyme in diet-treated animals. Cycloheximide experiments indicated that control and diet-adapted enzyme decreases in activity according to first-order kinetics with a calculated half-life of 10.3 and 6.5h after complete and phosphate-free diet administration respectively. Basal and diet-adapted enzymes exhibit similar K(m) values for several phosphomonoesters and an identical degree of inhibition is produced by cysteine. In addition, the enzyme from both sources is the same with regard to heat inactivation at 45, 56 or 64 degrees C, to the profile of elution from Sephadex and to electrophoretic properties on polyacrylamide gel. A failure of rat kidney alkaline phosphatase to respond to cortisol (hydrocortisone) was also observed.


A computer-based multi-channel system for automatic chemical analysis.


Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats. 1. The activities of 3-hydroxybutyrate dehydrogenase and 3-oxo acid CoA-transferase in rat brain at birth were found to be about two-thirds of those of adult rat brain, expressed per g wet wt. The activities rose throughout the suckling period and at the time of weaning reached values about three times higher than those for adult brain. Later they gradually declined. 2. At birth the activity of acetoacetyl-CoA thiolase in rat brain was about 60% higher than in the adult. During the suckling period there was no significant change in activity. 3. In rat kidney the activities of the three enzymes at birth were less than one-third of those at maturity. They gradually rose and after 5 weeks approached the adult value. Similar results were obtained with rat heart. 4. The activity of glutamate dehydrogenase (a mitochondrial enzyme like 3-hydroxybutyrate dehydrogenase and 3-oxo acid CoA-transferase) also rose in brain and kidney during the suckling period, but at no stage did it exceed the adult value. 5. Throughout the suckling period the total ketone-body concentration in the blood was about six times higher than in adult fed rats, and the concentration of free fatty acids in the blood was three to four times higher. 6. It is concluded that the rate of ketone-body utilization in brains of suckling rats is determined by both the greater amounts of the key enzymes in the tissue and the high concentrations of ketone bodies in the blood. In addition, the low activities of the relevant enzymes in kidney and heart of suckling rats may make available more ketone bodies for the brain.


Complex-formation between cytochrome c and cytochrome c peroxidase. Kinetic studies. 1. The kinetics of ferrocytochrome c peroxidation by yeast peroxidase are described. Kinetic differences between the older and more recent preparations of the enzyme most probably arise from differences in intrinsic turnover rates. 2. The time-courses of cytochrome c peroxidation by the enzyme follow essentially first-order kinetics in phosphate buffer. Deviations from first-order kinetics occur in acetate buffer, and are due to a higher enzymic turnover rate in this medium accompanied by a greater tendency to autocatalytic peroxidation of cytochrome c. 3. The kinetics of ferrocytochrome c peroxidation by yeast peroxidase are interpreted in terms of a mechanism postulating formation of reversible complexes between the peroxidase and both reduced and oxidized cytochrome c. Formation of these complexes is inhibited at high ionic strengths and by polycations. 4. Oxidized cytochrome c can act as a competitive inhibitor of ferrocytochrome c peroxidation by peroxidase. The K(i) for ferricytochrome c is approximately equal to the K(m) for ferrocytochrome c and thus probably accounts for the observed apparent first-order kinetics even at saturating concentrations of ferrocytochrome c. 5. The results are discussed in terms of a possible analogy between the oxidations of cytochrome c catalysed by yeast peroxidase and by mammalian cytochrome oxidase.


Chicken liver transfer ribonucleic acid: heterologous interaction of alanine transfer ribonucleic acid with yeast.


Cytoplasmic deoxyribonucleic acid in roots of Pisum sativum.


Physicochemical studies on chloroplast thylakoid protein from Phaseolus vulgaris.


Inhibition of the Hill reaction and photophosphorylation by 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT).


The effect of isonicotinyl hydrazide on the greening of maize and barley.


Complex-formation between cytochrome c and cytochrome c peroxidase. Equilibrium and titration studies. 1. Physical studies of complex-formation between cytochrome c and yeast peroxidase are consistent with kinetic predictions that these complexes participate in the catalytic activity of yeast peroxidase towards ferrocytochrome c. Enzyme-ferricytochrome c complexes have been detected both by the analytical ultracentrifuge and by column chromatography, whereas an enzyme-ferrocytochrome c complex was demonstrated by column chromatography. Estimated binding constants obtained from chromatographic experiments were similar to the measured kinetic values. 2. The physicochemical study of the enzyme-ferricytochrome c complex, and an analysis of its spectrum and reactivity, suggest that the conformation and reactivity of neither cytochrome c nor yeast peroxidase are grossly modified in the complex. 3. The peroxide compound of yeast cytochrome c peroxidase was found to have two oxidizing equivalents accessible to cytochrome c but only one readily accessible to ferrocyanide. Several types of peroxide compound, differing in available oxidizing equivalents and in reactivity with cytochrome c, seem to be formed by stoicheiometric amounts of hydrogen peroxide. 4. Fluoride combines not only with free yeast peroxidase but also with peroxidase-peroxide and accelerates the decomposition of the latter compound. The ligand-catalysed decomposition provides evidence for one-electron reduction pathways in yeast peroxidase, and the reversible binding of fluoride casts doubt upon the concept that the peroxidase-peroxide intermediate is any form of peroxide complex. 5. A mechanism for cytochrome c oxidation is proposed involving the successive reaction of two reversibly bound molecules of cytochrome c with oxidizing equivalents associated with the enzyme protein.


The effects of oestradiol on nucleoside transport in rat uterus. 1. By using the non-metabolized cytidine analogue, cytosine arabinoside, it was possible to examine the mechanism of nucleoside transport in the immature rat uterus in the absence of intracellular utilization of the permeant. It was demonstrated that the uptake of cytosine arabinoside is not accumulative and that it can be competitively inhibited by the addition of a second nucleoside, uridine. Introduction of a concentration gradient of uridine from the medium towards the intracellular water promotes the counterflow of cytosine arabinoside out of the cells against its concentration gradient. These properties indicate that a facilitated-diffusion system is involved in nucleoside transport in the uterus. Further counterflow studies have shown that the transport system has a broad specificity for purine and pyrimidine nucleosides and that it is distinct from the processes that mediate the uptake of sugars, amino acids and purine and pyrimidine bases. 2. Oestradiol injection has no effect on the initial rate of cytosine arabinoside uptake in vitro. The increased amount of the analogue taken up per uterus is simply due to the expansion of the uterine volume that accompanies oestrogen action. 3. It is concluded that the striking increase in uridine uptake, observed in vivo in uteri from oestrogen-treated rats, does not result from an increase in the initial rate of nucleoside transport into the intracellular space of the tissue.


Dextro-gamma-carboxymethyl-gamma-methyl-delta-alpha-butenolide. A 1,2-ring-fission product of 4-methylcatechol by Pseudomonas desmolyticum. 1. (+)-gamma-Carboxymethyl-gamma-methyl-Delta(alpha)-butenolide was isolated from resting-cell cultures of Pseudomonas desmolyticum incubated in the presence of 5-methylsalicylic acid. 2. The structure of this metabolite was deduced from physical and chemical evidence. 3. The isolated compound must be formed in an enzymic reaction since it shows optical activity. 4. The degradative pathway of 4-methylcatechol by Ps. desmolyticum is discussed.


A new type of bile salt.

A new type of bile salt.


Regulation of enzymes converting L-mandelate into benzoate in bacterium N.C.I.B. 8250.


Practical problems in a method of cluster analysis.


The purification and properties of a bacterial trimethylamine dehydrogenase.


Effects of collapsing multidimensional contingency tables.


Problems arising in estimating from retrospective survey data the latent periods of juvenile cancers initiated by obstetric radiography.


Markov chain methods in chain binomial epidemic models.


Estimation of hit number.

Estimation of hit number.


An examination and extension of Leslie's test of equal catchability.


An iterative procedure for analysing log-linear models.


Analysis of drug effects on body temperature.


Design of experiments: the single cycle sine wave model.


Graphical Monte Carlo type I error rates for multiple comparison procedures.


The sodium-potassium exchange pump. II. Analysis of Na + -loaded frog sartorius muscle. A model for the Na-K exchange pump was applied to data on Na(+)-loaded frog sartorius muscle, and was used to relate the rate of adenosine triphosphate (ATP) hydrolysis to the electrical properties of the cell membrane. Membrane hyperpolarization was considered to arise from an electrical current which was produced by the hydrolysis reaction coupled to ion movements, and which flowed across the membrane. The reaction rate, as calculated from hyperpolarization, agreed with direct measurements of ATP hydrolysis and with the rate estimated from Na(+) tracer efflux studies. Although Na(+) is actively extruded, the model showed that K(+) is inwardly transported if the potassium permeability of the membrane is less than about 6.6 x 10(-6) cm/sec, as is suggested by resistance data. Calculations indicated that the reaction conductance L(rr) was relatively constant when compared with the reaction rate and reaction free energy for large changes in internal and external ionic concentrations. Its value agreed with the value obtained from the dependence of Na(+) tracer efflux on external K(+). A set of experiments was suggested which would provide a more complete interpretation of the data.


An investigation of the bound water in tendon by dielectric measurement. The dielectric constant of natural tendon in the frequency range of 200 Hz to 100 kHz has been determined as a function of temperature (300-450 degrees K) for water concentrations ranging from about 6 to 16% by weight. The results compare well with the approach taken by Haggis and his coworkers. Based on the assumption that at low concentration of water the probability of water-water bonding is small and hence may be disregarded, a structure for water in the collagen matrix is proposed in which the water is either bonded in one of four possible states to the polar groups of the polypeptide chains, or is unbound. In determining the distribution of the water among these states an approach similar to that of Haggis and his co-workers, in conjunction with the order-disorder theory of Bragg and Williams, is used. The number of water molecules per unit volume is then determined experimentally by relating it to weight loss as a function of temperature, as determined by thermogravimetric analysis. The dispersion which is normally found in dipolar substances has not been found for tendon. A maximum in the value of the dielectric constant is observed to occur between 25 and 80 degrees C, the temperature depending upon the heating rate.


Kinetic theory model for ion movement through biological membranes. 3. Steady-state electrical properties with solution asymmetry. An electrodiffusion model for plasma membrane ion transport, which takes into account the influence of high electric field strengths and ion-membrane molecule interactions, is presented and analyzed. A generalized Nernst-Planck equation for steady-state situations is derived which has electric field-dependent mobility and diffusion coefficients. Under the assumption of a constant electric field within the membrane, this equation is integrated to give a more general form of the Goldman equation. Based on this equation numerical computations of ionic chord conductance as a function of applied electric field strength were carried out for several permeant ion concentration ratios. The model is capable of yielding significantly larger rectification ratios than is the Goldman equation. Further, high field asymptotes to the current vs. electric field strength curve do not generally intersect at the origin.


The independence principle. A reconsideration. The electrodiffusion model presented in the previous paper, which specifically excludes ion-ion interactions, is analyzed for the ratio of one-way fluxes (flux ratio) as a function of the ionic driving force across the membrane. Significant deviations from the behavior expected on the basis of the Ussing relation are found. These are sufficient to explain the "nonindependent" ion movement noted in some biological flux ratio data. One-way fluxes are dependent on the ionic concentration on both sides of the membrane. The coupling of these fluxes to ionic concentrations comes from the dependence of ionic mobility and the diffusion coefficient on the equilibrium potential. It is concluded that nonindependent behavior in experimental data is not sufficient to implicate ion-ion interaction as the source of the discrepancy.


Blood flow, slip, and viscometry.

Blood flow, slip, and viscometry.


Climbing behavior patterns in prepubertal rats. Effects of hormones, rearing conditions, and sensory cues.


A study on ineffective erythropoiesis in the dog.


Cartilage cell proliferation in the tail-vertebrae of new-born rats.


The relationship between cell maturation and proliferation in the erythroid system of the rat.


Cell proliferation during the course of immunological rejection of Ehrlich ascites tumour cells.


The technique of labelled mitoses: analysis by automatic curve-fitting.


Cleidocranial dysostosis. A clinical and cytological study.


Clinical applications of polymorphism in chromosome fluoresence.


Dominant mode of inheritance in atrial septal defect.


Autosomal dominant inheritance in Larsen's syndrome.


Amino acid composition of serum high density lipoprotein in patients with familial lecithin:cholesterol acyltransferase deficiency.


The adducted thumbs syndrome. An autosomal recessive disease with arthrogryposis, dysmyelination, craniostenosis, and cleft palate.


Studies on lichen enzymes. Purification and properties of an orsellinate depside hydrolase obtained from Lasallia pustulata.


Isolation and properties of tRNA nucleotidyl transferase from yeast.


Fatty acid synthetase from pig liver. 2. Characterization of the enzyme complex with oxidoreductase activity for alicyclic ketones as a fatty acid synthetase.


Biological activities of chemically modified endotoxins.


Studies on deoxyribonucleoprotein structure. Redistribution of proteins in mixtures of deoxyribonucleoproteins, DNA and RNA.


Steroids in meconium from male and female newborn infants.


Interaction between arginase and ornithine carbamoyltransferase in Saccharomyces cerevisiae. The regulatory site for ornithine.


Social differentiation in immature white mice.


Studies on the attachment of the bovine J blood-group substance at the erythrocyte membrane.


Interrelations of motile and metabolic activities in tissue culture cells. II. Motile activities in chick embryo fibroblasts locomoting on a network of glass wool fibres.


The influence of dipolienylphosphathydilcholine and dimaleinic 1-methylbutanoloamide of d-lisergic acid upon morphological and histochemical changes in the organs, caused by a prolonged application of carbon disulphide in white rats.


Changes in the diurnal rhythm of neurosecretory activity in the mouse following x-ray irradiation.


Activity of the pituitary-thyroid system during the neonatal period in the pig. II. Histology.


The relation between the heart rate and a complex of cardio-respiratory parameters during muscular exercise in male age groups.


Electron microscopic study of the development of the mouse corneal epithelium.


Beta radiation inhibition of corneal healing. I. Tensile strength and ultrastructure change.


Sorbitol pathway in the ciliary body in relation to accumulation of amino acids in the aqueous humor of alloxan-diabetic rabbits.


Electroretinographic evaluation of the Bunsen-Roscoe law for the human eye at high energy levels.


Glycosidases of the crystalline lens. II. Alterations in diabetic cataracts.


Amino acid transport by rabbit optic nerve in vitro.


Pornography and the sex offender: patterns of previous exposure and arousal effects of pornographic stimuli.


Anxiety as a function of intrinsic-extrinsic job orientation. The presence or absence of observers, and task difficulty.


Error and variability in the visual processing of dental radiographs.


Spatial and temporal information as cues in a time-sharing task.


Effects of alcohol ingestion on tracking performance during angular acceleration.


Influence of expectation of task duration on efficiency of muscular activity.


Studies on metapyrocatechase. IV. Circular dichroism and optical rotatory dispersion.


Effect of  -bromo-palmitate on the oxidation of palmitic acid by rat liver cells.


Facilitated diffusion. The case of carbon monoxide.


Acylation of  - and  -chymotrypsins by p-nitrophenyl acetate. Enzyme-substrate complex formation and pH dependence.


A kinetic approach to the mechanism of deoxyribonucleic acid cross-linking by HNO 2 .


The dissociation of the first oxygen molecule from some mammalian oxyhemoglobins.


Ternary coordination complexes between glycine, copper (II), and glycine peptides in aqueous solution.


Formation rates of the two ethyl isocyanide compounds of liver cytochrome P-450 at low temperatures.


Multiple active forms of thrombin. I. Partial resolution, differential activities, and sequential formation.


The mechanism of action of ethanolamine ammonia-lyase, a B 12 -dependent enzyme. 8. Further studies with compounds labeled with isotopes of hydrogen: identification and some properties of the rate-limiting step.


Multiple active forms of thrombin. II. Mechanism of production from prothrombin.


The chymotrypsinogens and procarboxypeptidases of chick pancreas.


Location of the saccharide binding site of concanavalin A.


Contribution of psychological reports to patient management.


Masculinity-femininity in obese women.

Masculinity-femininity in obese women.


Disclosing of verbal material as a function of information requested, information about the interviewer, and interviewee differences.


A and B subject-therapists' responses to videotaped schizoid and intropunitive-neurotic prototypes.


Diagnoses as moderators of the relationship between biographical variables and psychiatric decision in a combat zone.


Behavioral deficits in groups with cerebral vascular lesions.


An objective approach to measurement of interpersonal behavior in phenylketonuria.


Systematic desensitization as training in self-control.


A university freshman preventive intervention program: report of a pilot project.


Dimensions of problem behavior in the early grades.


Patients' self-perceived treatment needs and their relationship to background variables.


Perceived locus of control and personal adjustment.


Sex differences in ego functioning: exploratory studies of agency and communion.


Parental child-rearing attitudes and preadolescents' problem behaviors.


Concurrent validity of the Mosaic test for differential diagnosis between brain injury and schizophrenia.


Attitude similarity in marital therapy.

Attitude similarity in marital therapy.


Note on "Strangers in Paradise," or telling it like it isn't.


Immediate and delayed responses from memory in brain-damaged patients.


Elaboration training and paired-associate learning efficiency in children.


Teaching disadvantaged preschool children to think creatively with pictures.


Effects of variations in content and stimulus grouping on visual sequential memory.


Effects of memory support on state anxiety and performance in computer-assisted learning.


Verbal facilitation of paired-associate learning: a limited generalization?


A new familial form of convulsive disorder and mental retardation limited to females.


Otitis media in low-birth-weight infants.


The relationship between proved viral bronchiolitis and subsequent wheezing.


The Russell-Silver syndrome without asymmetry.


Hydrocephalus in Apert's syndrome.

Hydrocephalus in Apert's syndrome.


Aortic arch in the neck: a case report.

Aortic arch in the neck: a case report.


A simple rapid test for lead poisoning.

A simple rapid test for lead poisoning.


The unsuitability of random urinary delta aminolevulinic acid samples as a screening test for lead poisoning.


Maternal-fetal urea concentration difference in man: metabolic significance.


Malignant mesenchymoma of the cervix. Simple excision followed by long-term survival.


Pneumatosis intestinalis following pneumomediastinum in a newborn infant.


Dominant inheritance of Sprengel's deformity.


Deep thrombophlebitis associated with acute osteomyelitis.


Intravenous diazoxide for severe hypertension in childhood.


Sexual precocity: an unusual complication of propylthiouracil therapy.


Aspirin, platelets, and bleeding.

Aspirin, platelets, and bleeding.


Cortical hyperostosis with hyperphosphatemia.


Russell-Silver syndrome in siblings.

Russell-Silver syndrome in siblings.


A further warning on the use of salt as an emetic agent.


Familial selective deficiency of IgA.

Familial selective deficiency of IgA.


Effect of intermittency on stereopsis.

Effect of intermittency on stereopsis.


Behavioral correlates of the EEG in delinquents.


The relationship of cue strength and temporal interval to schizophrenic associative disorders.


Recognition paired-associate learning in preschool children.


Developmental factors in masturbation: family background antecedents and later personality patterns.


Relationship between kinesthetic and spiral aftereffect and Eysenck's theory of personality.


Effects of noncompetitive, competitive instructions, and sex on performance in a color-word interference task.


The effects of body size and body markings on nonpolarized schooling behavior of zebra fish (Brachydanio rerio).


Some correlates of negative reaction tendencies in institutionalized retarded children.


Reaction time as a function of magnitude estimations of vibrotactile internal noise.


Management of fluctuant hearing loss.

Management of fluctuant hearing loss.


Cushing's disease. St. Thomas Hospital.

Cushing's disease. St. Thomas Hospital.


Useful symptoms and signs in chest disease.


Rehabilitation and acute myocardial infarction.


Alcoholism: a social study on 200 patients.


Mechanism of action of thyroid hormone on the heart.


Somatic crossing-over in the housefly.

Somatic crossing-over in the housefly.


Interspecific transformation and DNA characteristics in Allomyces.


Genetic fine structure and function of mutants at the ilv1-gene locus of Saccharomyces cervisiae.


Chronic administration of antidepressants in animals.


Comparative effects of single and repeat dose administration of CNS stimulants.


Single and repeat dose effects of imipramine, chlorpromazine, perphenazine, and chlordiazepoxide in the mouse.


Differential behavioral and biochemical effects of yohimbine over time of administration.


Occipital alpha and accommodative vergence, pursuit tracking, and fast eye movements.


Information on clinical psychotropic drug studies--a request and a resource.


Visual evoked responses to emotional stimuli in the mentally retarded.


Operant conditioning of the human salivary response.


Frequency of the EEG during acquisition in short-term memory.


Individual differences in stimulus intensity response.


Physiological reactivity as a predictor of performance in a vigilance task.


Individual differences in orienting, conditionability, and skin resistance responsivity.


Habituation of the orienting reflex in brain damaged patients.


Comparative advantages of bipolar abraded skin surface electrodes over bipolar intramuscular electrodes for single motor unit recording in psychophysiological research.


Effects of depth and rate of breathing on heart rate and heart rate variability.


Direct measurement of skin conductance: a proposal for standardization.


Lightfoot, levers, and psychophysiology.


An electrically operated skin resistance switch.


Human reaction time and endogenous heart rate changes in normal subjects.


On the unlikelihood of non-aqueous biosystems.


Urease reaction rates at low water activity.


Exponential decontamination models for count data.


Polypeptides from the condensation of amino acid adenylates.


A computerized bacterial identification system as applied to planetary quarantine.


The application of acetolysis for releasing leaf cuticular membranes of Pandanus in taxonomic studies.


A portable dry-ice storage chamber for enhanced preservation of enzymes in frozen tissue specimens.


The effects of maternal hypercortisonism and hypervitaminosis D2 on fetal osteogenesis and ossification in rats.


Cytogenetic and teratologic studies on rats continuously infused with various doses of tritiated thymidine during pregnancy.


An investigation of dermatoglyphic asymmetry in rubella embryopathy.


Effects of 5 days of hypoxia on the blood of chick embryos.


Changes in DNA, RNA, and protein content of regions of explanted chicken embryos following insulin treatment.


Umbilical vein entering the right atrium: comments on a previously reported human case.


Symposium on Electophysiologic Correlates of Clinical Arrhythmias. 3. Contribution of His bundle recordings to the understanding of clinical arrhythmias.


Symposium on electrophysiologic correlates of clinical arrhythmias. 3. Wolff-Parkinson-White syndrome: a new look.


Artificial pacing of the human heart: its contribution to the understanding of the arrhythmias.


Patterns and mechanisms of QRS normalization in patients with Wolff-Parkinson-White syndrome.


Effects of lignocaine, propranolol and bretylium on ventricular fibrillation threshold.


Peripheral venous scintillation angiocardiography in determination of left ventricular volume in man.


Oscillatory flow patterns in patients iwth aortic valve disease.


A scintiphotographic method for measuring left ventricular ejection fraction in man without cardiac catheterization.


Attempted surgical division of the preexcitation pathway in the Wolff-Parkinson-White syndrome.


Recurrent Wolff-Parkinson-White tachycardia in an infant: successful treatment by a radio-frequency pacemaker.


The Wolff-Parkinson-White syndrome in advanced atrioventricular block.


Acute coronary insufficiency (impending myocardial infarction and myocardial infarction): surgical treatment by the saphenous vein graft technique.


Do we have enough cardiologists in the U.S.?


Arrhythmia, sudden death and coronary artery disease.


Drug abuse and medical leadership.

Drug abuse and medical leadership.


The concept of community. The short-circuit of the mental health movement.


Treatment of anxiety states.

Treatment of anxiety states.


Use of the couch in the psychotherapy of borderline patients.


The teaching of psychotherapy problems by computer.


Cluster analyses of life changes. I. Consistency of clusters across large Navy samples.


Cluster analyses of life changes. II. Method and replication in Navy subpopulations.


Scaling of life events.

Scaling of life events.


Differential catechol-O-methyltransferase activity in unipolar and bipolar affective illness.


Homovanillic and 5-hydroxyindoleacetic acid in cerebrospinal fluid of depressed patients.


Psychiatrists, employers, and information exchange.


Altered tyrosine daytime plasma levels in endogenous depressive patients.


Sensory hair fusion in vestibular sensory cells after gentamycin exposure. A transmission and scanning electron microscope study.


Surgical judgment in vascular surgery.

Surgical judgment in vascular surgery.


Emergency aortocoronary bypass for acute myocardial infarction.


Direct coronary arterial revascularization. Treatment of cardiac failure associated with coronary artery disease.


Aortocoronary bypass grafts. Early postoperative angiographic evaluation and reexploration for stenosis or thrombosis of the vein graft.


Coronary hemodynamics following aorta-coronary bypass graft.


Development of occlusive arterial disease in lower limbs. Angiographic follow-up of 705 medical patients.


Surgery for femoropopliteal atherosclerosis. A reappraisal.


Surgical treatment of the refractory postphlebitic ulcer.


Postoperative venous thrombosis and the effectiveness of prophylactic measures.


Changing orthopedic surgery. (1947-1970).


Medical vs surgical treatment of acute dissecting aneurysms.


Effect of dextrans on small arterial anastomosis.


Hemodynamics of experimental portacaval transposition. A promising procedure for decompression of portal hypertension.


Treatment of acute renal insufficiency after aortoiliac surgery.


Operative blood flow in femoral-popliteal and femoral-tibial grafts for lower extremity ischemia.


A clinicoanatomical study of the arcuate ligament of the diaphragm.


Emergency carotid thromboendarterectomy. Surgical indications and results.


Plasma renin activity following operations for renovascular hypertension.


Electrophysiological basis for supraventricular arrhythmias: following surgical procedures for aortic stenosis.


Unrecognized aortoiliac stenosis. A physiologic approach to the diagnosis.


Repair of late vein graft occlusions.

Repair of late vein graft occlusions.


Ultrasonic flow detector value in combat vascular injuries.


Circulatory arrest during deep hypothermia induced by peritoneal dialysis.


Valvular heart surgery in infants and children.


Too many "surgeons"?

Too many "surgeons"?


Transapical left ventricular bypass.

Transapical left ventricular bypass.


Circular dischroism of bradykinin and related peptides. 1. The circular dichroism of bradykinin and a number of its analogues and homologues was measured over the spectral range 200-300nm. All of the biologically active peptides showed maxima at 220nm and minima at 235nm. The spectra were independent of solvent and temperature. The vibronic transitions of phenylalanyl residues in the 250-280nm range showed no evidence of intra- or inter-molecular interactions. We take this as evidence that bradykinin and its biologically active analogues and homologues exist in solution as disordered chains. 2. None of the analogues with spectra unlike bradykinin possessed biological activity. However, peptides such as retro-bradykinin, des-6-serine-bradykinin, des-1-arginine-bradykinin and des-9-arginine-bradykinin produced spectra like that of bradykinin but were devoid of biological activity. Although we could not identify spectral features that were clearly correlated with biological activity, it appears unlikely that highly ordered peptides of the same amino acid composition as bradykinin would possess bradykinin-like effects.


The cross-linking of tyrosine by treatment with tetranitromethane. 1. Tyrosine was treated with tetranitromethane. 2. Approx. 10% of the tyrosine was converted into 3-nitrotyrosine. 3. Three fluorescent compounds were also formed. They appear to be a dimer, trimer and tetramer in which tyrosine units are linked by biphenyl bonds. 4. The dimer and trimer have also been isolated from some proteins after treatment with tetranitromethane. 5. The yield of 3-nitrotyrosine from ovotransferrin after treatment with tetranitromethane was much smaller than the loss of tyrosine. 6. Several unidentified compounds were also formed by the reaction between tyrosine and tetranitromethane.


Glycopeptides from human kappa-chains.

Glycopeptides from human kappa-chains. Glycopeptides have been isolated from tryptic digests of kappa-type light chains separated from human myeloma proteins obtained from the serum of two patients, Car and Rai. The glycopeptides are derived from the variable region of the chain in both cases, but from different sections. On the basis of homology it is deduced that glycopeptide from Car, kappaI type, is derived from position 25-31 whereas that from Rai, kappaII type, is from position 62-77, their sequences being respectively Ala-Ser-Gln-Asn-Ile-Ser and Phe-Ser-Gly-Ser-Gly-Ser-Gly(Thr,Asp)Phe-Thr-Leu-Asx-Ile-Ser-Arg. The significance of the results is discussed in connexion with the nature of the attachment site of carbohydrate to protein.


A study of permeability of lysosomes to amino acids and small peptides. The latency of nitrocatechol sulphatase activity was measured in rat liver lysosomes before and after preincubation in 0.25m solutions of five amino acids, three dipeptides and a tripeptide. Rates of increase in ;free' activity were taken as an indication of rates of solute penetration into lysosomes and were correlated with the structure of each molecule studied. In general permeability was greater in solutions of pH7 than of pH5 or 6, and dipeptides entered more rapidly than amino acids or triglycine. The conclusions are in good agreement with those obtained by other methods.


Heterogeneity of protein-polysaccharides of porcine articular cartilage. The sequential extraction of chondroitin sulphate-proteins with iso-osmotic neutral sodium acetate. Protein-polysaccharides of knee-joint cartilage of 9-month-old pigs were extracted sequentially with neutral iso-osmotic sodium acetate after five repeated homogenizations. One-third of the uronic acid originally present in the tissue was brought into solution, about half being in the first extract. The protein-polysaccharides, which were purified by precipitation with 9-aminoacridine, were heterogeneous in size on gel chromatography. The smallest (retarded by 6% agarose) were the most easily extracted since they were most prevalent in the initial extracts and absent from later ones, whereas the proportion of larger molecules increased progressively in successive extracts. Nevertheless a small proportion of the largest molecules (excluded from Sepharose 2B) was present even in the first extract. None of the protein-polysaccharide preparations contained hydroxyproline, and the analyses of their constituent sugars were the same, although there was a progressive increase in the protein content and in the glucosamine/galactosamine molar ratio of successive extracts. In each preparation this molar ratio was invariably greater in larger than in smaller molecules separated by gel filtration. From galactosamine/pentose molar ratios it appeared that the chondroitin sulphate chains were on average about 29 disaccharide units in length in the protein-polysaccharides of each extract, although gel-chromatography and cetylpyridinium chloride elution profiles showed that a somewhat higher proportion of shorter chondroitin sulphate chains occurred in the larger protein-polysaccharides. In the last extract, where the largest molecules predominated, about half could be reversibly dissociated by urea, whereas this had no effect on the protein-polysaccharides of earlier extracts even though these contained some large molecules.


The chemistry of the collagen cross-links. The absence of reduction of dehydrolysinonorleucine and dehydrohydroxylysinonorleucine in vivo. Two aldimine bonds have been shown to be present as stabilizing cross-links in intact collagen fibres from soft tissues: dehydrohydroxylysinonorleucine as a major component and dehydrolysinonorleucine being present in trace quantities. In the highly insoluble collagens less dehydrohydroxylysinonorleucine is present but the proportion of dehydrolysinonorleucine increases. In elastin the latter aldimine is reduced in vivo to give a more stable cross-link but no comparable reduction could be detected with either of the aldimines present in collagen.


Human small-intestinal  -galactosidases. Separation and characterization of three forms of an acid  -galactosidase. 1. An acid beta-galactosidase, optimum pH4.0-4.5, in the human small-intestinal mucosa was separated and characterized. 2. Autolysis of mucosal homogenates at acid pH inactivated the lactase and hetero beta-galactosidase; the total activity of the acid beta-galactosidase was only slightly depleted, but a greater proportion of the enzyme was solubilized by this treatment. 3. Separation on a Sephadex G-200 column revealed that the acid beta-galactosidase could occur in at least three different forms, probably representing monomer, dimer and octamer or polymer of the enzyme. 4. The properties of the different forms of the acid beta-galactosidase were studied with regard to pH optimum, K(m), rate of hydrolysis of different substrates, and sensitivity to p-chloromercuribenzoate and tris as inhibitors. All these properties were the same for the different forms of the enzyme. 5. The acid beta-galactosidase hydrolyses lactose as well as hetero beta-galactosides and contributes to the lactase activity of intestinal biopsies also when measured at pH 6. This enzyme may therefore be responsible for a considerable part of the residual lactase activity found in lactose-intolerant patients.


The  -amylase of the beetle Callosobruchus chinensis. Purification and action pattern. Callosobruchus chinensis larval amylase was isolated and purified in five steps, which included co-precipitation with glycogen and column chromatography on ECTEOLA-cellulose. The enzyme was homogeneous by disc gel electrophoresis on polyacrylamide. The alpha-amylase nature was evidenced by the action on amylopectin beta-amylase limit-dextrin, by the effect on the substrate-iodine complex and by the action pattern on several polysaccharide substrates. These action patterns are compared with those of other alpha-amylases.


The ultrasonic blood velocity detector as an aid to arteriography.


A constant depth ultrasonic scanner.

A constant depth ultrasonic scanner.


The nidus concept of spinal cord arteriovenous malformations. A surgical recommendation based upon angiographic observations.


The value of the plain radiograph in acute massive pulmonary embolism.


Comparison of cerebral toxicity of monomeric and trimeric forms of sodium iothalamate.


A review of pelvimetry data.

A review of pelvimetry data.


The determination of time-dose relationships from clinical data.


Pneumoencephalographic findings in a case of vein of Galen aneurysm.


An unusual manifestation of sarcoid.

An unusual manifestation of sarcoid.


A liver phantom for evaluating camera and scanner performance in clinical practice.


A simple kit for the percutaneous catheterization of small arteries.


Poor man's neutrons?

Poor man's neutrons?


Aetiological considerations of thyroid cancer.


Clinical and surgical aspects of thyroid tumours and endocrine associations of medullary carcinoma.


Radiotherapy of thyroid cancer.

Radiotherapy of thyroid cancer.


Diagnostic aspects of thyroid carcinoma.


Malignant lymphoma of the thyroid gland.


Cyclazocine treatment of opiate dependence: a progress report.


Male and female homosexuality: natural history.


Can psychiatry contribute to international conciliation?


Military psychiatry--theory and practice in noncombat areas: the role conflicts of the psychiatrist.


Social psychiatric consequences of job incompetence.


Onus-taking and onus-putting.

Onus-taking and onus-putting.


Group therapy: what specific therapeutic advantages?


Hope and discomfort as factors influencing treatment continuance.


Psychiatric assessment from documentary evidence.


Narcotic addiction--new approaches.

Narcotic addiction--new approaches.


The synthesis of collagen during the development of anal-fin processes in ethisterone-treated females of Oryzias latipes.


Experimental control of budding and stolon elongation in Perophora orientalis. A compound ascidian.


Study on the influence of the arterial pressure upon the morphology of cisternal CSF pulsations.


Arterial vascularisation and angioarchtitecture of the nucleus caudatus in human brain.


Observations on the efficacy of L-dopa in progressive supranuclear palsy.


The evaluation of the cerebral hemodynamics in ischemic stroke by the intravenous injection of hippuran  131 I.


Hereditary polyneuropathy, oligophrenia, premature menopause and acromicria. A new syndrome.


How to prevent death from bronchial asthma.


[Housing and domestic conditions of workers in railroad machine stations].


The effect of marginal gingivitis on tooth mobility.


A pressure-sensitive periodontal probe.

A pressure-sensitive periodontal probe.


Biometric comparison of three methods for determining the mucogingival junction.


Bone loss in Ramfjord's index: substitution of selected teeth.


Cytological evaluation of chemotoxic effects on the oral mucosa.


Splinting of teeth--an objective assessment.


Fluoride uptake by calculus following topical application of fluorides.


Further studies on the effects of coca chewing on exercise.


A cariogenic Actinomyces viscosus--a bacteriological and gnotobiotic study.


Areolar size during pubescence.

Areolar size during pubescence.


Anthropometric and functional evidence of heterosis from Egyptian Nubia.


Height, weight and chest circumference of children of different ethnic groups in Lourenço Marques, Moçambique, in 1965 with a note on the secular trend.


Comparative fitting of the Gompertz and logistic functions to longitudinal height data during adolescence in girls.


The interrelationship of pattern elements on soles.


Studies on polypeptides. XLIX. Fragment condensations with peptide derivatives related to the primary structure of ribonuclease T 1 .


Substrate-induced pK perturbations with chymotrypsin.


An evaluation of the DuVries modification of the McBride hallux abducto valgus correction. A preoperative, immediate postoperative, and longterm study.


Medial arthroplasty technique for the correction of helomas.


Hydrosonic therapy: immersed three-dimensional ultrasound. A 9-month clinical evaluation.


Ventilatory and metabolic responses of unanesthetized dogs to CO 2  at 2 and 18 C.


Solar heat load in man.

Solar heat load in man.


Physiological effects of localized ventilation.


Hypocapnia-induced increases in rectal temperature in man during heat exposure.


Survival of bilaterally adrenalectomized hamsters drinking saline sucrose.


Effect of pH on pulmonary pressor responses to humoral agents.


Effect of gravitoinertial force on ocular counterrolling.


Nervous control of renal circulation--on the existence of sympathetic cholinergic fibers.


Effect of arterial CO 2  tension on cerebral blood flow, mean transit time, and vascular volume.


Factors affecting upper airway resistance in conscious man.


Sweat lactate in man is derived from blood glucose.


Endurance exercise: effect of work-rest schedules and repeated testing.


Partitional calorimetry of the New Zealand white rabbit at temperatures 5-35 degrees C.


"Closing volume" and its relationship to gas exchange in seated and supine positions.


Temperature regulation against cold: effect of induced hyperthyroidism in men and women.


Hering-Breuer inflation reflex and regulation of breathing in conscious dogs.


Effect of short periods of hypoxia, hyperoxia, and hypercapnia on brain O 2  supply.


Metabolic responses to normoxia and hypoxia in the altitude-adapted rat during swimming.


Pneumotachograph for use with infants during spontaneous or assisted ventilation.


An artificial arterial system for pumping hearts.


Measurement of renal blood flow by a differential pressure technique in the cat.


A nonerosive electromagnetic flowmeter probe for chronic aortic implantation.


Static pulmonary compliance of man during altitude hypoxia.


Measurement of aortic blood flow in man by the computed pressure derivative method.


Cardiorespiratory measurements in fetal monkeys obtained by chronic catheters.


Characteristics of transducers used for recording the apexcardiogram.


Kamin effect in rats: index of memory or shock-induced inhibition?


Effects of successive and simultaneous lesions of somatosensory cortex on tactile discrimination in the rat.


Incubation effect in rats: decline of footshock-produced activation.


Acquisition of new responses by rats during chronic depression of acetylcholinesterase activity.


Effect of septal lesions in two strains of rats on one-way and shuttle avoidance acquisition.


Sexual responses of polygamous female and monogamous male rats to novel partners after sexual cessation.


Repeated variations in deprivation level: different effects depending on amount of training.


Cardiac activity in the mouse: strain differences.


Hippocampal lesions and inhibition of avoidance behavior.


Loss of behavioral thermoregulation after lateral hypothalamic lesions in rats.


The architecture of stratum corneum after wounding.


Cell proliferation in human fetal epidermis.


Free nerve endings of the epidermis in hairy and hairless mice.


Determination of the perfect state, mating type and elastase activity in clinical isolates of the Microsporum gypseum complex.


An orderly lattice of axial tubules which interconnect adjacent transverse tubules in guinea-pig ventricular myocardium.


The coronary microcirculation in the potassium chloride arrested heart.


The ventriculocaval shunt in the treatment of adult hydrocephalus. Results and complications in 101 patients.


On the fate of glycogen phosphorylase in the ischemic and infarcting myocardium.


Effects of subarachnoid hemorrhage from puncture of the middle cerebral artery on blood flow and vasculature of the cerebral cortex in the cat.


Ventriculoauriculostomy-associated infection. A 12-year study.


Pericardial tamponade by Holter ventriculoatrial shunts.


Biochemical changes in non-infarcted heart muscle following myocardial infarction.


Giant intracranial epidural meningioma. Case report.


An angiographic study of meningiomas of the posterior fossa.


Treatment of multiple intracranial aneurysms. Treatment of multiple intracranial aneurysms.


Chiasmapexy for the correction of traction on the optic nerves and chiasm associated with their descent into an empty sella turcica. Case report.


Spasm of the extracranial internal carotid artery resulting from blunt trauma demonstrated by angiography. Case report.


Viability of connective tissue cells following storage of aortic valve leaflets.


The flexible stent. A new concept in the fabrication of tissue heart valve prostheses.


The role of rejection and mechanical trauma on valve graft viability.


Collagen-derived heart valves; concept and experimental results.


Effective measures in the prevention of intraoperative aeroembolus.


Mesothelial fibrinolysis.

Mesothelial fibrinolysis.


Cardiac prosthesis utilizing biological material.


Ependymal cyst of the Sylvian fissure. Case report.


New developments in the design of fabric-covered prosthetic heart valves.


Transvenous stimulation of the phrenic nerves.


Intracardiac air following cardiotomy. Location, causative factors, and a method for removal.


Preclinical testing of a redundant, rechargeable cardiac pacemaker.


Extracorporeal support of the circulation by means of venoarterial bypass with an oxygenator. Case study of eight patients in shock.


Cavopulmonary anastomosis for cyanotic congenital heart disease.


Reconstruction of the main pulmonary artery with a valve-bearing tube graft made of autologous pericardium.


Supravalvular stenosis after disc mitral valve replacement.


Multisaccular aneurysm of the proximal descending thoracic aorta. Report of a case with associated coarctation.


Intraventricular rerouting of blood for the correction of Taussig-Bing malformation.


Aortocardiac fistula.

Aortocardiac fistula.


Traumatic ventricular septal defect, aortic insufficiency, and sinus aneurysm.


Lipid alterations and their reversion in the central nervous system of growing rats deficient in essential fatty acids.


Quantitative analysis of the phospholipids of some marine bioluminescent bacteria.


Effect of EFA deficiency on lipid transport from liver.


Studies on the role of phospholipids in the triglyceride cycle. 3. Liver and plasma phospholipid exchange in depancreatized dogs.


Effects of level and type of dietary fat on incidence of mammary tumors induced in female Sprague-Dawley rats by 7,12-dimethylbenz()anthracene.


Renal cerebroside in globoid cell leukodystrophy (Krabbe's disease).


The declaration of Geneva, 1948: a 1971 reappraisal.


Teaching postgraduate teachers how to teach.


Cardiac slowing, not cardiac irritability, the major problem in the prehospital phase of myocardial infarction.


Urinary calculi in Fiji Indians. The curry kidney.


Molluscum contagiosum in villages of the West Sepik District of New Guinea.


Disseminated intravascular clotting complicating viral pneumonia due to influenza.


Laryngeal cytology. Histological basis and clinical applications.


A curiosity in medicine.

A curiosity in medicine.


Recent advances in contraceptive technology.


The position of tubal ligation in family planning.


Conditions of membership of the A. M. A.


Storage of rubella serum.

Storage of rubella serum.


Rebates from benefit organizations.

Rebates from benefit organizations.


National health service.

National health service.


Fourth Australian Medical Congress. Concurrent session: hormones and reproduction.


Fourth Australian Medical Congress. Concurrent session: normal and abnormal blood formation and destruction.


The Twenty-fifth World Medical Assembly.


More tuberculosis beds released.

More tuberculosis beds released.


Stress and psychiatry.

Stress and psychiatry.


Migration and suicide.

Migration and suicide.


Antidepressant overdosage in children--a new menace.


Plastic chatheter embolism to the right heart. A technique of non-surgical removal.


Knee instability my foot.

Knee instability my foot.


Systemic candidiasis in an infant treated with 5-fluorocytosine.


A future for the medical and health care services in Australia.


National Health Service.

National Health Service.


The most common fee.

The most common fee.


The analgesic powder.

The analgesic powder.


The management of stuttering.

The management of stuttering.


Scientific and medical aspects of the Australian Andean expedition.


Prescribing of oral contraceptives to minors.


The good samaritans.

The good samaritans.


Survival in childhood leukemia.

Survival in childhood leukemia.


The education of the doctor.

The education of the doctor.


Twenty-second session of WHO Western Pacific Regional Committee.


Whither virology?

Whither virology?


Effect of mersalyl, ethacrynic acid and sodium sulphate infusion on urinary acidification in hereditary renal tubular acidosis.


A comparison of the post-mortem blood-alcohol levels of drivers and passengers compared with those of drinking drivers who kill pedestrians.


Post-mortem blood alcohol survey in some Australian states.


Pyuria and bacteriuria in patients admitted into a psychiatric hospital.


Amniotic fluid embolism.

Amniotic fluid embolism.


A universal ligature applicator.

A universal ligature applicator.


Histiocytic medullary reticulosis.

Histiocytic medullary reticulosis.


Addition of drugs to intravenous fluids.


A statement on abortion in Victoria.

A statement on abortion in Victoria.


Permanent gluten intolerance.

Permanent gluten intolerance.


L-dopa-variation in response with different pharmaceutical preparations (Syndopa vs. Larodopa).


Hay fever and corticosteroids.

Hay fever and corticosteroids.


Cot deaths.

Cot deaths.


New appliances: an automatic skin clip applier.


Patients and strangers.

Patients and strangers.


Arthrodesis of the hip joint. Current indications and technique.


Thromboembolism after elective surgery of the hip. Detection, natural history, prophylaxis, and results with low molecular weight dextran.


An evaluation of the ring total hip joint prosthesis. A preliminary report.


Synovectomy of the knee.

Synovectomy of the knee.


Proximal tibial osteotomy for degenerative arthritis of the knee.


Arthroplasty and arthrodesis of the knee joint.


Total knee joint replacement prosthesis.


Some observations on present-day hip surgery.


Cup arthroplasty.

Cup arthroplasty.


Effects of radiation on the thrombocytopoietic system of mice.


Electrical conductivity and cholinergic activity of the rat gastric mucosa, at 4 and 170 hours after 600 R x-irradiation.


Effect of continuous gamma irradiation of chick embryos upon hatchability and growth.


Survival time response of the Mongolian gerbil after total body irradiation.


Report to the Radiation Research Society by its nineteenth president.


Prognostic significance of concentrations of four classes of protein-bound carbohydrates in the serum of dogs.


The effect of extreme hypoxia on recovery after radiation by synchronized mammalian cells.


Radiation chemistry of some sulfonephthalein dyes.


Oxygen and carbon dioxide tensions in experimental wounds.


The abuse of blood transfusions.

The abuse of blood transfusions.


Captains are courageous.

Captains are courageous.


Technical considerations in combined valvular replacement and coronary artery bypass operations.


Brain tolerance to impact in football.

Brain tolerance to impact in football.


Developmental neurophysiology of the human brain.


The development of gallstones.

The development of gallstones.


Reduction of experimental wound infection with iodized gut sutures.


An evaluation of manometric operative cholangiography in 100 patients with biliary disease.


Lymph node-breast carcinoma interrelations in tissue culture.


Surgical treatment of carcinoma of the floor of the mouth.


Vascular tumors of the parotid region in children.


The recurrent laryngeal nerve in thyroid operations.


Fatty acid toxicity.

Fatty acid toxicity.


Chemical modification of phyllotaxis and its implications.


The time needed to set up a gradient: detailed calculations.


Ultrastructure of rat uterine luminal epithelium at functional states compatible with implantation.


Effects of puromycin on chick embryo lung development in vitro.


The early development of the pars distalis of human foetal pituitary gland.


Gas chromatography-mass spectrometry in forensic chemistry for identification of substances isolated from tissue.


The N-terminal tryptic peptide of rabbit muscle aldolase.


Further characterization and cellular localization of an ATP: triacetic acid lactone lyase in pigeon liver.


Investigation on the relationship between dose and energy response of the photon radiation in film dosimetry.


A kinetic model for calculations of the number of tRNA molecules.


Biology and mathematics. II. Probability and biology.


Studies on orchidaceae alkaloids. XXV. N-isopentenyl derivatives of dendroxine and 6-hydroxydendroxine from Dendrobium friedricksianum Lindl. and Dendrobium hildebrandii Rolfe.


Separation and characterization of three proline peptidases from a strain of Arthrobacter.


On the effect of tension on myosin.

On the effect of tension on myosin.


Acid degradation of lignin. IV. Analysis of lignin acidolysis products by gas chromatography, using trimethylsilyl derivatives.


Studies on orchidaceae alkaloids. 23. Alkaloids from Liparis loeselii (L.) L. C. Rich. and Hammarbya paludosa (L.) O. K.


Control and modification of methods for determination of  15 N in biological material.


Structural studies on the O-specific side-chains of the cell-wall lipopolysaccharide from Salmonella newington.


Structural studies on the O-specific side-chains of the cell-wall lipopolysaccharide from Salmonella parathyphi A var. durazzo.


Constituents of umbelliferous plants. XVI. Terpenoids from the root of Selinum carvifolium L.


Diagnose this unusual case in gastroenterology.


The patient as a "paramedical" worker.

The patient as a "paramedical" worker.


Exchange of views: the forgotten addict.


A clinical view of the amphetamines.

A clinical view of the amphetamines.


Levodopa in treating Parkinsonism.

Levodopa in treating Parkinsonism.


Endoscopic diagnosis of esophageal varices.


Serum immunoglobulins and five serum proteins in extrahepatic obstructive jaundice and alcoholic cirrhosis. Immunoglobulins and proteins in liver diseases.


The histopathology of the pharynx and esophagus in oculopharyngeal muscular dystrophy. Case report and literature review.


Psychology and national health care.

Psychology and national health care.


Carcinoma of the hepatic duct bifurcation.


Crystallization of glycerol 3-phosphate dehydrogenase, triosephosphate dehydrogenase, arginine kinase, and cytochrome c from a single extract of honeybees.


Malaria eradication: a tangled web.

Malaria eradication: a tangled web.


Relationship of ATP:AMP phosphotransferase isozymes to tissue respiration.


A comparison of some properties of microsomal cytochrome P-450 from normal, methylcholanthrene-, and phenobarbital-treated rats.


Acidic and basic amino acid transport systems of Penicillium chrysogenum.


Transport of vitamin B 12  in Ochromonas malhamensis.


The metabolism of D- and L-lysine in the chicken.


Synthesis of phenylalanyl-arginyl-leucyl-aspartic acid: a model study of the coupling of arginine-terminal tryptic fragments of proteins.


Purification and characterization of glucose-6-phosphate isomerase from Bacillus stearothermophilus.


Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: evidence for homologous enzymes.


Lactate dehydrogenase isoenzymes: distribution in fast-twitch red, fast-twitch white, and slow-twitch intermediate fibers of guinea pig skeletal muscle.


The substrate recognition site of collagen proline hydroxylase: the hydroxylation of -X-Pro-Gly- sequences in bradykinin analogs and other peptides.


Studies on the spatial relationship between intestinal disaccharidases and the phlorizin-sensitive transport of glucose.


The nitrate dependence of the inhibition of photosynthesis by carbon monoxide in Chlorella.


Thyroxine-induced mitochondrial protein and its effect on respiration.


Effect of fatty acids on xanthine dehydrogenase synthesis in the chick.


The estimation of redox potentials of cytochromes in mitochondria.


Ribosomal protein synthesis in Duchenne muscular dystrophy.


Physicochemical investigations on buffalo  -lactoglobulin. Studies on sedimentation, diffusion, and hydrogen ion titration.


Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in microsomes from rat tissues: differential inhibition and stimulation by benzoflavones and organic solvents.


An automated atmospheric radon sampling system.


Use of statistical techniques to assess progress toward a clean air environment: Houston, Texas.


Area-wide distribution of lead, copper, and cadmium in air particulates from Chicago and Northwest Indiana.


The determination of nitrogen dioxide in air after absorption in a modified alkaline solution.


Modified roller drum apparatus for analyzing effects of pollutant gases on tissue culture systems.


Cardiolipin and cytochrome AA 3  in intact liver mitochondria of rats. Evidence of successive formation of inner membrane components.


The effect of ultrasonic irradiation on the chemical structure of egg lecithin.


Isolation and characterization of a water-soluble protein from bovine erythrocyte membranes.


Exterior proteins on the human erythrocyte membrane.


Selective uptake and metabolism of androgens by rat epididymis. The prescence of a cytoplasmic receptor.


Pyrimidine biosynthesis in rat liver: studies on the source of carbamoylphosphate.


Peptidase activity in the membranes of Mycoplasma laidlawii.


Transport of iron by mycobactin in Mycobacterium smegmatis.


Evidence for the formation of membranous chromatophore precursor fractions in Rhodopseudomonas spheroides.


The effect of Gram negative endotoxin on the calcium uptake activity of sarcoplasmic reticulum isolated from canine myocardium.


Biogenesis of ubiquinone in rats--an alternate origin of the benzoquinone moiety.


Modification, permethylation and mass spectrometry of arginine-containing oligopeptides at the 100 nanomolar level.


ATP and pH induced spectral changes of cytochrome b in rat liver mitochondria.


Transfer RNA-primed oligoadenylate synthesis in maize seedlings. 3. Deoxyoligonucleotide primers.


Relative turnover rates of proteins and peptides of rat liver fatty acid synthetase.


A role for DNA in the formation of nuclear estradiol-receptor complex in a cell-free system.


Incorporation of label from D- -hydroxy( 14 C)butyrate and (3- 14 C)acetoacetate into amino acids in rat brain in vivo. The metabolism of ketone bodies by rat brain was studied in vivo. Rats starved for 48h were given either d-beta-hydroxy[3-(14)C]butyrate or [3-(14)C]acetoacetate by intravenous injection and killed after 3 or 10min. Total radioactivity in the acid-soluble material of the brain and the specific radioactivities of the brain amino acids glutamate, glutamine, aspartate and gamma-aminobutyrate were determined. A group of fed animals were also given d-beta-hydroxy[3-(14)C]butyrate. In the brains of all animals (14)C was present in the acid-soluble material and the specific radioactivity of glutamate was greater than that of glutamine.


Kinetics and mechanisms of catalase in peroxisomes of the mitochondrial fraction. 1. The primary intermediate of catalase and hydrogen peroxide was identified and investigated in peroxisome-rich mitochondrial fractions of rat liver. On the basis of kinetic constants determined in vitro, it is possible to calculate with reasonable precision the molecular statistics of catalase action in the peroxisomes. 2. The endogenous hydrogen peroxide generation is adequate to sustain a concentration of the catalase intermediate (p(m)/e) of 60-70% of the hydrogen peroxide saturation value. Total amount of catalase corresponds to 0.12-0.15nmol of haem iron/mg of protein. In State 1 the rate of hydrogen peroxide generation corresponds to 0.9nmol/min per mg of protein or 5% of the mitochondrial respiratory rate in State 4. 3. Partial saturation of the catalase intermediate with hydrogen peroxide (p(m)/e) in the mitochondrial fraction suggests its significant peroxidatic activity towards its endogenous hydrogen donor. A variation of this value (p(m)/e) from 0.3 in State 4 to 0 under anaerobic conditions is observed. 4. For a particular preparation the hydrogen peroxide generation rate in the substrate-supplemented State 4 corresponds to 0.17s(-1) (eqn. 6), the hydrogen peroxide concentration to 2.5nm and the hydrogen-donor concentration (in terms of ethanol) to 0.12mm. The reaction is 70% peroxidatic and 30% catalatic. 5. A co-ordinated production of both oxidizing and reducing substrates for catalase in the mitochondrial fraction is suggested by a 2.2-fold increase of hydrogen peroxide generation and a threefold increase in hydrogen-donor generation in the State 1 to State 4 transition. 6. Additional hydrogen peroxide generation provided by the urate oxidase system of peroxisomes (8-12nmol of uric acid oxidized/min per mg of protein) permits saturation of the catalase with hydrogen peroxide to haem occupancy of 40% compared with values of 36% for a purified rat liver catalase ofk(1)=1.7x10(7)m(-1).s(-1) and k'(4)=2.6x10(7)m(-1). s(-1)(Chance, Greenstein & Roughton, 1952). 7. The turnover of the catalase ethyl hydrogen peroxide intermediate (k'(3)) in the peroxisomes is initially very rapid since endogenous hydrogen peroxide acts as a hydrogen donor. k'(3) decreases fivefold in the uncoupled state of the mitochondria.


The diglyceride kinase of rat cerebral cortex. 1. Formation of phosphatidic acid by diglyceride kinase (EC 2.7.1.-) in the presence of ATP and Mg(2+) was shown in a homogenate and subcellular fractions of rat cerebral cortex. 2. The kinase was activated by Mg(2+). Ca(2+) activated to a smaller extent but was inhibitory in the presence of optimum concentration of Mg(2+). Activity was greatly increased in the presence of added 1,2-diglyceride. 3. Sodium deoxycholate markedly stimulated the reaction, but other detergents (Cutscum and Triton X-100) did not. 4. Diglyceride kinase was concentrated in the supernatant and microsomal fractions from rat cerebral cortex. The distribution of the kinase in the particulate fractions resembled that of acetylcholinesterase and 5'-nucleotidase. 5. The rate of phosphatidic acid synthesis by the diglyceride kinase route was much greater than reported rates for acylation of 3-glycerophosphate and was also very rapid in comparison with the rates of other steps in the synthesis of phosphoinositides. 6. Acetylcholine had no stimulatory effect on diglyceride kinase of isolated intact nerve-ending particles or of nerve-ending membranes obtained after osmotic shock.


Studies on metabolism of vitamin A. The effect of vitamin A status on the secretion rates of some steroids into the ovarian venous blood of pregnant rats. 1. Rats raised on a vitamin A-deficient diet supplemented with either retinyl acetate or retinoic acid were mated and became pregnant. 2. The rates of secretion of progesterone, 20alpha-hydroxypregn-4-en-3-one, oestradiol-17beta and oestrone into the ovarian-venous blood of rats in these two groups were measured on days 9 and 15 of pregnancy. 3. Rates of secretion of progesterone and 20alpha-hydroxypregn-4-en-3-one, both on days 9 and 15, were lower for the rats given retinoic acid. No such differences were found in ovarian oestrogen secretion. 4. The implications of these results are discussed in the light of the previous demonstration that the activity of ovarian 3beta-hydroxy-Delta(5)-steroid dehydrogenase was markedly less in pregnant rats given retinoic acid.


Permeability of housefly mitochondria towards dicarboxylate ions.


Regulation mechanism for fatty acid and  -ketoglutarate oxidations.


Dielectrophoresis of chloroplasts.

Dielectrophoresis of chloroplasts.


Osmotic regulation of photosynthetic glycerol production in Dunaliella.


Are specific chlorophyll-protein complexes required for photosynthesis?


Reactions at 77 degrees K in photosystem 2 of green plants.


The relationship between Q, C- 550  and cytochrome b 559 in photoreactions at -196 degrees in chloroplasts.


The light-induced oxidation-reduction reactions of menaquinone in intact cells of a green photosynthetic bacterium, Chloropseudomonas ethylica.


Fluorescence induction studies in isolated chloroplasts. 3. On the electron-transfer equilibria in the pool of electron acceptors of photosystem II.


Iron-containing proteins in Chromatium. I. Solubilization of membrane-bound cytochrome.


Some properties of five non-allelic  -D-fructofuranosidases (invertases) of Saccharomyces.


Orthopedic rehabilitation of the stroke patient. Rehabilitation of hemiplegic patients begins with setting reasonable functional goals and a treatment plan to reach them. During the initial illness an effort is made to begin range of motion exercising and positioning to prevent contractures. Transfer from bed to chair is recommended as soon as the patient's general condition permits.Upper extremity function depends on sensory and motor function as well as visual and central cerebral impairment. Spastic symptomatic contracture of the shoulder must be prevented by adequate orthopedic management of any musculoskeletal problems such as arthritis or tendinitis and the initiation of an active exercise program. Surgical release of contractures is occasionally indicated in refractory cases. Elbow flexion and pronation flexion deformity of the forearm and hand have also required surgical release on occasion. The goal of lower extremity function is ambulation. A double upright short leg brace aids stability in gait. Long leg braces are not used but a cane may be necessary for balance assistance. Contractures must be prevented by an exercise program or surgically released.


Transmission of rubella vaccine virus from vaccinees to contacts. The report presents evidence of the transmission of hpv-77 derived rubella vaccine virus from vaccinees to two susceptible contacts. The first instance of transmission was to a child who served as a transmission control on a "closed" study ward, and the second was to an antibody-negative mother in an "open" family study. Neither of these persons had any clinical evidence of rubella. Both had significant increases in rubella hemagglutination inhibiting (hai) antibody titers, but detectable complement fixing (cf) antibodies did not develop in either. With the kind of antigen used in our rubella cf test, this pattern of serologic response is characteristic of, but not diagnostic of, infection with the rubella vaccine virus. The serological evidence which was compatible with rubella vaccine virus infection, the complete absence of serologic or clinical evidence of "wild" rubella virus infections among the other four rubella susceptible transmission control children and the security precautions employed to ensure isolation on the "closed" ward, make "wild" rubella virus infection extremely unlikely. The evidence for rubella vaccine virus infection in the other susceptible contact is not as conclusive, because "wild" rubella virus infection is difficult to rule out in any person living in an "open" family situation. Nevertheless the need for more data is emphasized by the virtual certainty that rubella vaccine virus transmission did occur in the subject on the isolation ward, plus the high probability that the infection observed in the family group setting also represented transmission of rubella vaccine virus. Such data can only come from close surveillance of recipients of live rubella virus vaccines and their contacts in the future.


Indications for coronary arteriography: risks vs. benefits. Coronary arteriography has become a diagnostic procedure which is no longer limited to major medical centers but is being performed in many community hospitals. The procedure carries an appreciable risk, which is only justifiable by specific benefits to the patient. The benefits are related to the potential availability of newer surgical procedures of bypassing obstructive coronary arterial lesions. A specific set of criteria for the performance of coronary arteriography has been developed from a critical analysis of the ratio of risk to benefit. A survey of the risk of coronary arteriography indicates that mortality increases at least twentyfold and morbidity sixfold when this procedure is performed in laboratories with a low caseload as compared with high caseload institutions. Thus there appears to be no justification for performing coronary arteriography in the absence of proper team facilities.


Medical complications of heroin addiction. These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from transcriptions, they are prepared by Drs. Sydney E. Salmon and Robert W. Schrier, Assistant Professors of Medicine, under the direction of Dr. Lloyd H. Smith, Jr., Professor of Medicine and Chairman of the Department of Medicine. Requests for reprints should be sent to the Department of Medicine, University of California, San Francisco, San Francisco, Ca. 94122.


Malaria transmission among narcotic addicts. A report of ten cases and review of the literature.


Duodenocolic fistula.

Duodenocolic fistula.


Nephrotic syndrome.

Nephrotic syndrome.


Retrieval of catheter fragments. Report of two cases.


A synergistic danger in ketamine and Innovar.


Penicillin reactions.

Penicillin reactions.


The antibiotics and the peripheral nerves.


Cerebrospinal fluid after death.

Cerebrospinal fluid after death.


Anatomo-electrographic aspects in familial periodic paralysis.


Familial postero-lateral myelopathy and angiomatosis retinae.


Addison-Schilder's disease. Report of a case with probable relapsing addisonian encephalopathy.


Auditory receptor organs of reptiles, birds, and mammals.


Old and new data on tone perception.

Old and new data on tone perception.


Simple cells of the striate cortex.

Simple cells of the striate cortex.


Relations and possible significance of taste bud cells.


A model of fatigue.

A model of fatigue.


The nature of taste receptor sites.

The nature of taste receptor sites.


A telemetric method for assessing mental performance.


An analysis of eye movements during a visual task.


Relations between the symptoms and the feeling of fatigue.


Fatigue in industry. Understanding fatigue in modern life.


Psychological rating of human fatigue.

Psychological rating of human fatigue.


Evaluation of methods for the determination of factors inducing fatigue in man at work.


The blink method as an assessment of fatigue.


Fatigue assessment in relation to industrial conditions. Direct estimation of circulatory fatigue using a bicycle ergometer.


Mechanical and physiological efficiency of muscular work with different muscle groups.


Experimental studies of muscular fatigue of Bengalees with increasing work loads under different environmental conditions.


The measurement of fatigue in hot working conditions.


Heat stress in outdoor manual workers in East Africa.


The understanding of complaints in a noisy workshop.


Unusual cerebral and spinal symptoms in extradural sacral cyst.


Study of evoked responses in proximal muscles of the superior and inferior limbs.


Further studies concerning the detection of carriership in the Duchenne type of dystrophy.


Resting and pentagastrin-stimulated gastroesophageal sphincter pressure in patients with Zollinger-Ellison syndrome.


Relationships of gastrin dose, serum gastrin, and acid secretion.


Effect of distal antrectomy on gastric emptying of liquids and solids.


Parietal cell mass in healthy human stomach.


Effect of jejunal amino acid perfusion and exogenous cholecystokinin on the exocrine pancreatic and biliary secretions in man.


Relationship of bile acid pool size to biliary lipid excretion and the formation of lithogenic bile in man.


Morphological studies of rejection in canine jejunal allographs.


Absorption of water, unconjugated bilirubin, and sodium glycodeoxycholate by the rabbit gallbladder with dietary-induced gallstones.


Progress in liver disease: physiological factors involved in the causation of cirrhotic ascites.


Comparison of serum clearance and urinary excretion of mesobilirubinogen-H 3  in control subjects and patients with liver disease.


Surgical management of regional enteritis.


Inhibitory mechanisms in duodenal control of gastric acid secretion.


An economical approach to esophageal manometry and pH recording.


Mechanisms of malabsorption and malnutrition in the blind loop syndrome.


Selection and appointment of gastroenterology fellows and trainees.


Etiology of lactase deficiency: another perspective.


Effects of unilateral Ménières disease on masking-level differences.


Monaural detection with contralateral cue (MDCC). IV. Psychometric functions with sinusoidal signals.


Effects of attenuation step on descending Békésy threshold.


Influence of pulsed masking on spondee words.


Speaker sex recognition of 5- and 6-year-old children's voices.


Acoustical consequences of lip, tongue, jaw, and larynx movement.


Diagnosis and treatment of childhood cancer. A statewide attack.


Surgical aspects of childhood cancer.

Surgical aspects of childhood cancer.


Brain tumors of childhood.

Brain tumors of childhood.


Current management of retinoblastoma.

Current management of retinoblastoma.


Diagnosis and management of neuroblastoma in children.


Primary bone tumors in children.

Primary bone tumors in children.


Skin and soft tissue cancer.

Skin and soft tissue cancer.


We, the AMA.

We, the AMA.


The teaching hospital and the school of medicine. A plan for affiliation.


Maintaining physician competence.

Maintaining physician competence.


Organization. Podiatrists, the other doctors.


Formaldehyde condensation. A method for the fluorescence microscopic demonstration of peptides with NH 2 -terminal tryptophan residues.


Cholinesterase activity in the human fetal heart between the 35- and 160-millimeter crown-rump length stages.


The use of dextran in phosphatase techniques employing lead salts.


Amino acid sequences of free and blocked N-termini of Leopard shark immunoglobulins.


Direct observations on the effect of "proliferation inhibitory factor" on the clonal growth of target cells.


Dual pathways of complement interaction with guinea pig immunoglobulins.


A factor in maternal plasma during pregnancy that suppresses the reactivity of mixed leukocyte cultures.


Fate and immunogenicity of antigens endocytosed by macrophages: a study using foreign red cells and immunoglobulin G.


Inheritance and strain distribution of a rat immunoglobulin allotype.


Effect of age upon primary alloantigen recognition by mouse spleen cells.


Enhancement of hemolytic complement activity by treatment of human serum with iodine.


Immune fever in the rabbit: responses of the hematologic and complement systems.


The relationship of complement consumption to immune fever.


The Georgia Regional Medical Program.

The Georgia Regional Medical Program.


The Mass Casualty Plan: some basic concepts. Medical Association of Georgia Committee on Emergency Medical Services.


The surgical treatment of carotid artery obstructions.


Acute abdominal pain and a "bump" on the left diaphragm.


Comments on current burn therapy.

Comments on current burn therapy.


The clinical recognition of pericardial disease.


A conformational study of catecholamine receptor sites. 5. Syntheses of dl-3-amino-2-(3,4-dihydroxyphenyl)-trans-2-decalol hydrochlorides.


A conformational study of catecholamine receptor sites. 6. Syntheses of dl-3-amino-2-(3,4-dihydroxyphenyl)-trans-2-decalin hydrochlorides.


Synthesis and alkaline decomposition of 5-alkyl-5-(1-methyl-3-oxobutyl)barbituric and 2-thiobarbituric acid derivatives.


Inhibitors of platelet aggregation. 1. 5,10-Dihydro-3-(phenyl, thienyl, and furyl)thiazolo(3,2-b)(2,4)benzodiazepines and related compounds.


Studies on the inhibition of glyoxalase I by S-substituted glutathiones.


Synthesis and biological activity of some 5-(1-adamantyl)pyrimidines. 2.


2-Alkylthioadenosines, specific coronary vasodilators.


Antitumor activity of some quaternary ammonium compounds. Structure-activity relationship.


Aminobenzoic acid diuretics. 2. 4-Substituted-3-amino-5-sulfamylbenzoic acid derivatives.


Minimal statistical data for structure-function correlations.


Synthesis and local anesthetic activity of certain piperazine and ephedrine derivatives.


Synthesis and toxicology of 5,7-dibenzyloxycyclopentenone(2,3-c)coumarin. A model compound of aflatoxin B 1 .


Antitumor agents. Schiff bases from benzaldehyde nitrogen mustards and 2-phenyl-4-((3-amino-4-methoxy)phenyl)thiazole.


Synthesis, alkylation, and oxidation of thieno(3,4-c)- and -(3,2-c)pyrazoles.


Some halogenated acetyl derivatives and their antitumor activity.


Synthesis and biological study of a series of S-substituted  -mercaptohippuramides and nitriles.


Seeds as sources of L-dopa.

Seeds as sources of L-dopa.


Mannich derivatives of medicinals. 2. Derivatives of some carbonic anhydrase inhibitors.


Analogs of albizziin.

Analogs of albizziin.


Conversion of ergosterol into the estrogen neoergosterol by direct peroxide cleavage.


Trans-2-aminoethyl 2-acetoxycinnamates. Potential analgetic antiinflammatory agents.


Derivatives of fluorene. 34. N 1 -acetyl-N 2 -fluorenylasparagines.


Cold caloric test for prognosis of brain injuries.


Partial laryngectomy and laryngoplasty.

Partial laryngectomy and laryngoplasty.


Cellular reactions in acute otitis media--scanning and transmission electron microscopy.


Bekesy audiometry: threshold recruitment and rhythm factors.


Audiologic findings in acoustic neuroma.


[Histological investigation of testis in infertile man. I. Some clinical problems on testicular biopsy].


Histological investigation of testis in infertile man. II. Pathological problems.


The role of mast cells in human liver cirrhosis.


Electron microscopic studies on the adrenal of rat treated with aminoglutethimide--with special reference to accumulation of cholesterol in intramitochondrial vacuoles.


A study of increased permeability of vasa vasorum.


Study on role of reticuloendothelial system in metabolic regulation.


Notes on digestive diseases. 3. The lower esophageal ring.


Voluntary sterilization of the male: a survey of elective vasectomies performed by Washington State urologists.


Vagotomy: truncal, selective or none. A plea for common sense in the choice of operation for peptic ulcer.


Disposable radiopaque grid for intrauterine fetal transfusion and other uses.


Crossed renal ectopia: a diagnostic trap.


Telephone recall system for periodic cervical cytologic examinations.


Establishing the efficacy of psychotropic agents.


Report of the conference on the use of stimulant drugs in the treatment of behaviorally disturbed young school children.


Biological effects of pharmaceutical agents--metabolic and chemical aspects.


Recent advances in application of neurophysiological methods to psychopharmacology.


Influence of acute infection on the metabolism of zinc and other trace elements.


A longitudinal study of trace metal therapy in the copper loaded schizophrenic patient.


Method of obtaining basophils by filtration.


Behavioral deficit with zinc deficiency.


Blood histamine levels, basophil counts, and trace metals in the schizophrenias.


An analysis of the effects of trace metals on brain electrical activity in rabbits and in man.


EEG studies of the hyperkinetic child.

EEG studies of the hyperkinetic child.


Details for the fluorometric determination of histamine, spermidine, and spermine after sequential separation of phosphorylated cellulose.


Review of stimulant drugs in learning and behavior disorders.


Results of a followup radiation survey on color television sets, Suffolk County, New York.


Gross radioactivity in surface waters of the United States, January 1971.


1. Radionuclides in institutional diet samples, January-March 1971.


Radioactivity in New York surface water July-December 1969 and January-June 1970.


Radioactivity in airborne particulates and precipitation.


Strontium-90 in human bone, October-December 1970.


Environmental levels of radioactivity at Atomic Energy Commission installations.


The importance of DNA repair mechanisms in cancer therapy.


Radioisotope labels for the study of leukocyte kinetics. I.


Determination of hydroxyurea in mammalian tissues and blood.


Unidirectional Na flow in rat jejunem before and during intravenous infusion of 0.9 per cent NaCl.


Membrane glycoproteins of human blood platelets.


Elastolytic protease in blood platelets.


Adenine nucleotides and platelet function.


Interferon production by blood leucocytes in Hodgkin's disease.


Lipid metabolism in human platelets.

Lipid metabolism in human platelets.


Action of antilymphocytic serum on the electrophoretic mobility of human lymphocytes, platelets and erythrocytes.


Energy metabolism of aggregating platelets.


Some effects of combining close, punitive, and supportive styles of supervision.


The role of hydrophobic bonding in the thermoprecipitation of a pyroglobulin.


Science policy in perspective.

Science policy in perspective.


Technology assessment and its social context.


On "summe" and "Ganzheit".

On "summe" and "Ganzheit".


Observable versus inferred entities: pragmatic and phenomenological considerations.


An unusual form of chronic lymphatic leukaemia showing a delayed response to extracorporeal irradiation of the blood.


Ultrastructural anomalies in mononuclear cells of peripheral blood in S.L.E.: Presence of virus-like inclusions.


Intramitochondrial bodies in sheep adrenal zona glomerulosa cells.


Functional organization of the vasomotor centre.


Behaviour of the coronaries in the gas-perfused isolated heart.


Arterio-venous anastomoses in the kidney. 8. Intrarenal circulation during haemorrhagic hypotension.


Periodicity in conditioned performance: fourier analysis and autocorrelation of performance curves of rats.


Sensitizing property of papain digested rabbit IgG Fab and Fc fragments.


Effect of pretreatment and treatment with isoproterenol on experimental massive pulmonary embolism in the rat.


Age-independent anthropometry.

Age-independent anthropometry.


Relative values of different fat folds in a nutritional survey.


Lack of an effect of oral L-histidine on the serum cholesterol in human subjects.


Factors influencing the nutritive value of 1,2-dichloroethane-extracted fish protein concentrate in rat diets.


Folate levels in citrus and other juices.


Effect of caloric restriction and excessive caloric intake on energy expenditure.


Long-term energy intake and expenditure of obese housewives.


Determining energy costs of agricultural activities by respirometer and energy balance techniques.


Energy expenditure studies in military populations using Kofranyi-Michaelis respirometers.


Heart-rate telemetry for evaluation of the energy expenditure of children with cerebral palsy.


Use of the SAMI heart-rate integrator in malnourished children.


Energy expenditure and oxygen handling efficiency of anemic school children.


Measurement of free-range activity in children as modified by social and environmental complexity.


Energy expenditures and heart rates of Cambridge boys at school.


Energy expenditure of elderly people living alone or in local authority homes.


Estimating the energy expenditure of housekeeping activities.


Heart rate in middle-aged men.

Heart rate in middle-aged men.


Energy expenditure and heart rate of obese high school girls.


Relationship between habitual physical activity and physical fitness.


Hypercoagulability in the dysmature syndrome.


Inhibition of uterine contractility in labor.


The outcome of pregnancy in class A diabetes mellitus.


Epinephrine and norepinephrine in pregnancy. A comparative study of the adrenal gland and catechol output in different species of animals and man.


Uterine blood flow and O2 consumption following fetal death in sheep.


Relationship between amniotic fluid triglyceride levels and fetal maturity.


Abnormal progesterone synthesis in placental tissue from a spontaneous abortion.


The relation of serum 17-hydroxyprogesterone and estradiol-17-beta levels during the human menstrual cycle.


Pelvic arteriography in the differential diagnosis of pelvic mass.


A primary melanocarcinoma of the cervix.


Effect of prenatal administration of testosterone on ovarian function in rats.


I. Regeneration of rabbit endometrium following curettage.


Therapeutic abortion. A social work view.


Catalogue of arthropod-borne and selected vertebrate viruses of the world. The Subcommittee on Information Exchange of The American Committee on Arthropod-Borne Viruses.


A prospective study of the dangers of central venous pressure monitoring.


Pulmonary nocardiosis.

Pulmonary nocardiosis.


Operative cholangiograms.

Operative cholangiograms.


Malignant thymoma in a child.

Malignant thymoma in a child.


Fibulectomy: a radical decompression of the post-ischemic leg.


Chronic afferent loop obstruction.

Chronic afferent loop obstruction.


An amoebic liver abscess presenting as a space occupying lesion of the right kidney.


Simplified dressing technics.

Simplified dressing technics.


Closure of wounds of the stomach and pancreas with tissue adhesive and autoplastic peritoneum patch: an experimental study.


Effects of totally synthetic, low phenylalanine diet on adolescent phenylketonuric patients.


SH (Australia) antigen in early life.

SH (Australia) antigen in early life.


Fate of hypoplastic lungs after repair of congenital diaphragmatic hernia.


Effect of scoliosis on growth of alveoli and pulmonary arteries and on right ventricle.


Blood pressure recording in children.

Blood pressure recording in children.


Renal excretion of water in infants with acute gastroenteritis.


Uraemia as a determinant of convulsions in acute infantile hypernatraemia.


IgA deficiency in children. A clinical study with special reference to intestinal findings.


Endemic skeletal fluorosis.

Endemic skeletal fluorosis.


Disseminated intravascular coagulation and the Waterhouse-Friderichsen syndrome.


Cretinism: early diagnosis and its relation to mental prognosis.


Height and weight at menarche and a hypothesis of menarche.


Pathogenesis of respiratory syncytial virus diseases in infancy.


Coeliac disease. Reappraisal of clinical diagnosis.


Cyclophosphamide therapy in prepubertal rats and subsequent reproductive performance.


Phenobarbitone in neonatal jaundice.

Phenobarbitone in neonatal jaundice.


Plasma glutamine in a phenylketonuric family with normal and mentally defective members.


Cephalhaematomata with disseminated intravascular coagulation.


Intramural jejunal haematoma after peroral mucosal biopsy in a child with intestinal malrotation.


Familial haemophagocytic reticulosis in first cousins.


Transient metastatic calcification complicating renal failure in an infant.


Familial occurrence of single ventricle.


Endocarditis in the neonatal period.

Endocarditis in the neonatal period.


Rippling mattress worked from compressed air supply.


The respiratory jacket: a method for measuring static compliance in conscious children.


Early fed prematures: relation between fluid balance and weight change during first 4 days.