Congenital nephropathy associated with hearing loss, ocular abnormalities, mental retardation, convulsions and abnormal E.E.G.


Diurnal change of plasma insulin in diabetics with sulfonylurea treatment.


Effect of administration of thiamine, riboflavin, ascorbic acid and vitamin A to students on their pantothenic acid contents in serum and urine.


The Pickwickian syndrome in a child.

The Pickwickian syndrome in a child.


In vivo appearance and function of the termination of the ileum as observed directly through a cecostomy.


Steroid and hypokalemic myopathy after corticosteroids for ulcerative colitis. Systemic and tropical application.


"Pseudotumor" of the stomach simulated by splenic artery tortuosity.


A comparative study of the effects of histamine and betazole hydrochloride on secretory capacity of the human stomach.


Rheumatoid arthritis and the xylose tolerance test.


Effects of lesions in medial forebrain bundle on self-stimulation behavior.


Fatty acid, epinephrine, and glucagon hyperglycemia in normal and depancreatized sheep.


Myocardial mechanics in ppillary muscles of the rat and cat.


Effect of manganese on transmembrane potential and contractility of atrial muscle.


Effects of parabiosis of normal with genetically diabetic mice.


Nuclear RNA polymerase activity in acute hemodynamic overload in the perfused heart.


Warfarin metabolism and vitamin K requirement in the warfarin-resistant rat.


Effect of ceruloplasmin on plasma iron in copper-deficient swine.


Secretion ofpotassium by perfused excretory duct of rat submaxillary gland.


Platelet volume: effect of temperature and agents affecting platelet aggregation.


Influence of absolute flow rate and rouleau formation on plasma skimming in vitro.


Left ventricular mechanics and oxygen consumption during arterial counterpulsation.


Catabolsm of human beta-2-microglobulin by the rat kidney.


Effects of cyanide on renal concentration and dilution.


Electrical stimulation of esophageal smooth muscle and effects of antagonists.


Pattern of discharge of respiratory neurons during systemic vasomotor waves.


Stochastic properties of individual motor unit interspike intervals.


Characteristics of inhibition of gastric secretion by secretin.


Kidney growth and adaptation of phosphate-dependent glutaminase in the mouse.


Effects of acute renal ischemia on aerobic metabolism of dog kidney homogenates.


Active ion transport by isolated gastric mucosae of rat and guinea pig.


Changes in light scattered by striated muscle during excitation-contraction coupling.


Intracellular accumulation of nitrofurantoin by rabbit renal cortical slices.


Effect of estrogen and progesterone on uterine blood flow of castrate sows.


Amino acid balance and food intake: effect of amino acid infusions on plasma amino acids.


Activatioof muscle afferents by nonproprioceptive stimuli.


Transmitter release and responses of arteries and veins during nerve stimulation.


Effect of oxygen tension on glucose metabolism in rabbit kidney cortex and medulla.


Effect of sodium pyruvate infusion on acid-base balance and gas exchange in the dog.


Effect of magnesium deficiency on electrolyte distribution in the rabbit.


Physiological responses to heat stress in the poorwill.


Uptake of 28 Mg and 45Ca by tissues of magnesium-deficient rabbits.


Sodium and potassium secretion by isolated insect Malpighian tubules.


Effects of K, Na, and ouabain on urate and PAH uptake by snake and chicken kidney slices.


A micropuncture study of water transport by dog jejunal villi in vitro.


Ionic basis of intestinal electrical activity.


Ionic dependence of slow waves and spikes in intestinal muscle.


Ruptured omphalocele of the newborn.

Ruptured omphalocele of the newborn.


Parathyroid adenomas: experience at Good Samaritan Hospital.


Second gastric resection for recurrent peptic ulcer.


Leiomyosarcoma of the gastrointestinal tract.


Probable growth of venous-right pulmonary artery anastomosis and failure of growth of an arterial-left pulmonary artery anastomosis in the same infant.


Intestinal obstruction due to food.

Intestinal obstruction due to food.


The "changing epidemiology" of mortality in duodenal ulcer hemorrhage.


Isolation of diphtheroid bacilli from synovial membrane and fluid in rheumatoid arthritis.


Familial ankylosing vertebral hyperostosis with tylosis.


Intracellular enzymes and kinin enzymes in synovial fluid in joint diseases. Origin and relation to disease category.


Iron absorption in rheumatoid arthritis.


Ultrastructural changes in the synovial membrane in lipohaemarthrosis.


Clearnace of Fe59-labelled erythrocytes from normal and inflamed rabbit knee joints. I. Relationship to the anaemia of rheumatoid arthritis.


Development of tumors in hamsters by in utero injection of adenovirus type 12 into fetuses.


Observation of booster infections of measles in mothers of children with measles.


Regulaion of amylase synthesis by Vibrio parahaemolyticus.


Interaction of O-antigen with heated bacterial cells.


Finding of a g-determinant in the flagella of Salmonella haelsingborg.


Studies on the combined use of killed and live measles vaccines. IV. Fou years follow-up.


Highly inhibitory antibody fraction against enzymic activity of egg white lysozyme on a small substrate.


Coproporphyrinogenase activity in extracts from Rhodopseudomonas spheroides.


The effect of incubation with puromycin on the dissociation of rat liver ribosomes into active subunits.


The effect of oestrogen on the activity and binding of multiple forms of hexokinase in the rat uterus.


Poly r-U directed ambiguous amino acid incorporation in the rabbit reticulocyte system.


Mass spectrometry of polar complex lipids. Analysis of a sulfatide derivative.


Gas-liquid chromatography-mass spectrometry of cerebrosides as trimethylsilyl ether derivatives.


A new micro-scale synthesis of lactose.

A new micro-scale synthesis of lactose.


Carbon-13 magnetic resonance studies of carbon-13 enriched amino acids.


Identification of epsilon-N-monomethyllysine and epsilon-N-trimethyllysine in rabbit skeletal myosin.


Determination of glycosphingolipid structures by mass spectrometry.


(35S)-Atractyloside binding to mitochondrial membranes.


Changes in leucyl-tRNA during spontaneous and induced metamorphosis of bullfrog tadpoles.


The peptide moiety of human-blood-group active glycoproteins associated with the ABO and Lewis groups.


Iodination of insulin in aqueous and organic solvents. 1. The iodination of insulin was studied under various experimental conditions in aqueous media and in some organic solvents, by measuring separately the uptake of iodine by the four tyrosyl groups and the relative amounts of monoiodotyrosine and di-iodotyrosine that are formed. In aqueous media from pH1 to pH9 the iodination occurs predominantly on the tyrosyl groups of the A chain. Some organic solvents increase the iodine uptake of the B-chain tyrosyl groups. Their efficacy in promoting iodination of Tyr-B-16 and Tyr-B-26 is in the order: ethylene glycol and propylene glycol approximately methanol and ethanol>dioxan>8m-urea. 2. It is suggested that each of the four tyrosyl groups in insulin has a different environment: Tyr-A-14 is fully exposed to the solvent; Tyr-A-19 is sterically influenced by the environmental structure, possibly by the vicinity of a disulphide interchain bond; Tyr-B-16 is embedded into a non-polar area whose stability is virtually independent of the molecular conformation; Tyr-B-26 is probably in a situation similar to Tyr-B-16 with the difference that its non-polar environment depends on the preservation of the native structure.


Linoleic acid and linolenic acid elongation products in muscle tissue of Sncerus caffer and other ruminant species. The metabolic elongation products of both linoleic acid and linolenic acid were found in muscle tissues of Syncerus caffer and other ruminants. The acids with four double bonds were predominantly in the linoleic acid series, whereas the higher degrees of unsaturation, mainly five double bonds, were in the linolenic acid series. The total linoleic acid and linolenic acid groups were present in the relative proportions of about 4:1, in contrast with the fish oils, where the acids are mainly in the linolenic acid series. The consistent occurrence of members of both groups of acids in the animals studied here suggests to us that both may be important for structural purposes.


Inhibition of pyrophosphatase activity of mouse duodenal lkaline phosphatase by magnesium ions. Duodenal alkaline phosphatase of juvenile (11-day-old) mice, like other non-specific alkaline phosphatases, has the ability to hydrolyse PP(i). When a constant Mg(2+)/PP(i) concentration ratio is maintained, plots of velocity as a function of PP(i) concentration are consistent with Michaelis-Menten kinetics. Mg(2+) activates pyrophosphate hydrolysis and maximal activity is obtained at a constant Mg(2+)/PP(i) concentration ratio of 0.66. At higher ratios there is strong inhibition. At constant concentrations of Mg(2+) and increasing concentrations of PP(i), the velocity-substrate (PP(i)) concentration plots show sigmoidal dependence. By assuming that the true substrate is MgP(2)O(7) (2-) complex, and using complexity constants, the concentrations of free Mg(2+), Mg(2)P(2)O(7) and MgP(2)O(7) (2-) were calculated in assay mixtures ranging in PP(i) concentration from 0.1 to 2.5mm and in total Mg(2+) concentration from 0.6 to 2.6mm. From these data, the concentrations of added Mg(2+) and PP(i) in the assay mixtures were selected so that the velocity could be measured (1) at three fixed concentrations of free Mg(2+) ions with varied concentrations of MgP(2)O(7) (2-) and (2) at four fixed concentrations of Mg(2)P(2)O(7) with varied concentrations of MgP(2)O(7) (2-). Lineweaver-Burk and Hill plots from these data showed that the inhibition is caused by free Mg(2+) ions, of a mixed type and consistent with Michaelis-Menten kinetics. The sigmoidal dependence observed between velocity and PP(i) concentration at constant concentration of total Mg(2+) is therefore not due to allosteric inhibition. It is due to a combined effect of (1) inhibition by free Mg(2+) ions, (2) depletion of the true substrate, MgP(2)O(7) (2-), owing to the formation of Mg(2)P(2)O(7) and (3) the manner in which the concentrations of these three molecular or ionic species change when PP(i) concentration is increased maintaining the total Mg(2+) concentration constant.


Substrate specificity and kinetic properties of alpha-galactosidases from Vicia faba. 1. The hydrolysis of a variety of galactosides and other glycosides by alpha-galactosidases I and II of Vicia faba was studied. 2. The effect of temperature on kinetic parameters was also examined. 3. Both enzymes are inhibited by excess of substrate (p-nitrophenyl alpha-d-galactoside); with enzyme I this is competitive and is caused by the galactosyl moiety. 4. Enzyme I is inhibited by oligosaccharides possessing terminal non-reducing galactose residues and to a smaller extent by l-arabinose and d-fucose. 5. The effect of pH on K(m) and V(max.) values suggests that carboxyl and imidazole groups are involved in the catalytic activity of enzyme I. 6. Photo-oxidation experiments with enzyme I also suggest that an imidazole group is present at the active site.


Activation of liver succinate dehydrogenase in rats exposed to hypobaric conditions. 1. On brief exposure of rats to hypobaric conditions, the activity of hepatic mitochondrial succinate dehydrogenase was raised from the basal state to a ;partially activated state'. This was further raised to ;fully activated state' by preincubation of mitochondria with succinate, as was the activity in mitochondria from normal rats. 2. On washing mitochondria with the homogenizing sucrose medium the activity excess obtained on preincubation with succinate was lost in mitochondria from both normal and treated rats. 3. The enzyme in the ;partially activated state' from animals exposed to hypobaric conditions was stable to the washing procedure but was labilized and reverted to a low basal state of activity on freezing and thawing of the isolated mitochondria. 4. The results suggest that activation of succinate dehydrogenase under hypobaric conditions represents a conformational change leading to a stable, partially activated, form of the enzyme system: this is the first evidence of physiological modulation of this rate-limiting step in the control of the rate of oxidation of succinate.


Properties and biosynthesis of a neurotoxic protein of the venoms of s snakes Laticauda laticaudata and Laticauda colubrina. 1. A neurotoxic protein similar to erabutoxins a and b of Laticauda semifasciata was isolated in crystalline form from the venoms of Laticauda laticaudata and Laticauda colubrina. The name ;laticotoxin a' is proposed. 2. Laticotoxin a is homogeneous by CM-cellulose column chromatography, disc electrophoresis and ultracentrifugation and by terminal amino acid analyses. 3. Laticotoxin a consists of 62 amino acid residues. The molecular weight by ultracentrifuging is 6520. 4. The minimal 50% lethal dose of laticotoxin a by intramuscular injection to mice is 0.13mug./g. body wt. The toxin attacks the postsynaptic membrane, competing with acetylcholine. 5. Radioactive amino acids are incorporated into laticotoxin a in vivo. The incorporation is inhibited by puromycin, suggesting that the biosynthesis of the toxin follows the mechanism of protein biosynthesis, although the toxin molecule is rather small as a protein.


Differential stability of 28s and 18s rat liver ribosomal ribonucleic acids. Rat liver ribosomal RNA (rRNA) free from nuclease contaminants was isolated by a modification of the phenol technique. The 28s and 18s rRNA species were separated by preparative agar-gel electrophoresis. The two rRNA species were heated at different temperatures under various conditions and the amount of undegraded rRNA was determined by analytical agar-gel electrophoresis. The 18s rRNA remained unaltered after heating for up to 10min. at 90 degrees in water, acetate buffer, pH5.0, or phosphate buffer, pH7.0. Under similar or milder conditions 28s rRNA was partially degraded, giving rise to a well-delimited 6s peak and a heterogeneous material located in the zone between 28s and 6s. The dependence of degradation of 28s rRNA on the temperature and the ionic strength of the medium was studied. The greatest extent of degradation of 28s rRNA was observed on heating at 90 degrees in water. It is suggested that the instability of rat liver 28s rRNA is due to two factors: the presence of hidden breaks in the polymer chain and a higher susceptibility of some phosphodiester bonds to thermal hydrolysis.


Purification and characterization of bovine aorta ribonucleases. 1. Two ribonucleases (aorta ribonuclease I and aorta ribonuclease II) from bovine aorta were purified 4611-fold and 667-fold respectively. Ethanolic precipitation, acid extraction, isoionic precipitation at pH3.5 and Bio-Rex 70 column chromatography were the methods employed. 2. Aorta ribonuclease I exhibited no deoxyribonuclease or alkaline phosphatase activity. 3. Aorta ribonuclease I appeared to be homogeneous when subjected to discontinuous gel electrophoresis. 4. Aorta ribonuclease II exhibited the same properties as aorta ribonuclease previously isolated. 5. The activities of the aorta ribonucleases and pancreatic ribonuclease on homopolymers and dinucleoside phosphates were compared. 6. Aorta ribonuclease I exhibited optimum pH7.5 and, under the assay conditions used, optimum temperature 60 degrees .


Titration of ribonuclease T1.

Titration of ribonuclease T1.


Pig liver esterase. Some kinetic properties.


Intramolecular singlet excitation transfer. Applications to polypeptides.


Proton magnetic resonance studies of the cation-binding properties of nonactin. I. The K+-nonactin complex.


Oligodeoxythymidylate: polydeoxyadenylate and oligodeoxyadenylate: polydeoxythymidylate interactions.


Human liver mitochondrial monoamine oxidase. 3. Kinetic studies concerning time-dependent inhibitions.


The heterogeneity of histones. I. A quantitative analysis of calf histones in very long polyacrylamide gels.


Structural and functional factors in the hydrogen bonding of polar organic solvents to acid-soluble collagen. Effect on renaturation kinetics and thermal stability.


Regulation of hepatic glycogen synthetase of Rana catesbeiana. I. The effect of insulin treatment.


Characterization of the aggregated states of glycogen phosphorylases by gel electrophoresis.


Studies on steroid hydroxylase. Molecular properties of adrenal iron-sulfur protein.


Contribution of aromatic residue interactions to the stability of myoglobin. IV. Delineation of binding forces between aromatic compounds and myoglobin.


A study of the biosynthesis of deoxyribose in wheat embryos.


Phytol-derived C19 di- and triolefinic hydrocarbons in marine zooplankton and fishes.


Murine histocompatibility-2 (H-2) alloantigens. Purification and some chemical properties of soluble products from H-2b and H-2d genotypes released by papain digestion of membrane fractions.


Conformations of cyclic peptides. IV. Nuclear magnetic resonance studies of cyclo-pentaglycyl-L-leucyl and cyclo-diglycyl-L-histidyldiglycyl-L-tyrosyl.


The single-stranded polyadenylic acid-poly-L-lysine complex. A conformational study and characterization.


Computed circular dichroism spectra for the evaluation of protein conformation.


Use of sodium dodecyl sulfate, alone, to separate chromatin proteins from deoxyribonucleoprotein of Arbacia punctulata sperm chromatin.


Mössbauer spectroscopic evidence for the electronic configuration of iron in horseradish peroxidase and its peroxide derivatives.


The biosynthesis of conium alkaloids uring carbon-14 dioxide. The kinetics of 14C incorporation into the known alkaloids and some new alkaloids.


Complement-dependent damage to liposomes prepared from pure lipids and Forssman hapten.


The biosynthesis of conium alkaloids. Identification of a novel nonnitrogenous base from Conium maculatum as 3-formyl-4-hydroxy-2H-pyran.


Dissociation of chicken egg-white macroglobulin into subunite in acid. Hydrodynamic, spectrophotometric, and optical rotatory measurements.


Use of synthetic substrates to study binding and catalysis by lysozyme.


Medium chain triglycerides.

Medium chain triglycerides.


Antibacterial chemotherapy.

Antibacterial chemotherapy.


The treatment of vaginal infection with nifuratel.


Recurrent pancreatitis caused by peptic ulceration in an intra-pancreatic gastrireduplication cyst.


Obstructed femoral hernia in young children.


The misused reticulocyte.

The misused reticulocyte.


A comparative trial of beclomethasone dipropionate and flurometholone in general practice.


The role of puberty in red-cell production in hereditary haemolytic anaemias.


Haemolysis and erythropoiesis. II. Reticulocytosis and rate of haemoglobin rise in haemolytic and deficiency anaemias.


Diurnal variations of the serum iron in normal subjects and in patients with haemochromatosis.


Comparison of phospholipid and fatty acid composition of human erythrocytes and platelets.


Effect of ethanol on liver delta-aminolaevulinate synthetase activity and urinary porphyrin excretion in symptomatic porphyria.


Wiskott-Aldrich syndrome: qualitative platelet defects and short platelet survival.


Extracorporeal irradiation of blood by ultra-violet light in four cases of chronic lymphocytic leukaemia.


Chronic lymphocytic leukaemia treatment by splenic irradiation.


Cytological and cytogenetic study of lymphocytes during treatment of chronic lymphocytic leukaemia by ECIB.


Comparison of the action of ionizing and ultra-violet radiation on lymphocytes in vitro.


Selective lymphopenia produced by chronic irradiation of lymphatic tissue.


VDRL test in normal albino and pigmented rabbits.


Erythromycin in early syphilis.

Erythromycin in early syphilis.


Effect of 2-mercaptoethanol treatment on anticardiolipin reactivity in sera from syphilitics and false positive reactors.


Kanamycin sulphate in the management of gonorrhoea failing to respond to penicillin.


Treatment of gonorrhoea by one oral dose of ampicillin and probenecid combined.


Influence of pH on vaginal discharges.

Influence of pH on vaginal discharges.


Persistent urethritis associated with staghorn calculus of the kidney.


Sexually acquired gonorrhoeal urethritis in a 6-year-old bod.


Platelet aggregation by lathyric collagen.


Kinetics of the transition of titanium dioxide prepared by sulfate process and chloride process.


The kinetic studies of the acid-catalyzed etherification of the tautomers of p-nitrosophenol and p-benzoquinoneoxime with ethanol in dioxane.


The patient: a statistic or a person.

The patient: a statistic or a person.


Kinetic study of the polymerization of diallyl carbonate.


Physician opinions about continuing education programs. Highlights of findings in part II of a survey in California. A socio-economic report of the ureau of Research and Planning, California MedicalAssociation.


Informed consent regarding "the pill" and new drugs. In prescribing certain drugs, it is prudent for the physician to give the patient information on the advantages and disadvantages of the medication. This is especially true when patients request the oral contraceptive, popularly known as "the pill." Because of the sensational publicity relating to possible side effects from the pill, we know from past experience in other similar situations that serious patient questions may arise out of real or fancied effects from use of the pill.CMA has prepared two Health Tip articles: one devoted exclusively to the pill, and the other entitled How Does Your Doctor Know When a New Drug Is Safe? The two articles are available in quantity through CMA and are reprinted below. It is suggested that each physician consider giving the two articles to every patient seeking a prescription for the pill, and the drug article to all patients receiving certain other drugs-and in addition, the physician should make an entry in the patient's record of the delivery of the articles. In this fashion, "informed consent" could occur without the physician being required to be a lecturer but with the explanation to the patients being uniform and being done in a friendly, understandable manner. The dissemination of this data by the physician with the corresponding entry in the patient's record has a relationship to the continuation of the physician-patient rapport. The importance of an entry in the patient's record of whatever information you give cannot be overemphasized. The two articles reprinted here may be ordered in quantity for this purpose at nominal cost from CMA Health Tips. (See Order Blank at end of article.)


Hypotension and the shock syndrome in myocardial infarction.


Northern California epilepsy program.

Northern California epilepsy program.


Total retropubic prostatectomy for carcinoma of the prostate. Results in 96 patients who had total retropubic prostatectomy were reviewed. The most common complications were impotence and difficulty with urinary control. The most serious were rectal injury and vesical neck contracture. Twenty-eight of 33 patients who were followed for five years after operation and eight of twelve who were followed for ten years were alive without evidence of recurrence of cancer. Evidence of recurrence was found only in patients in whom cancer had spread beyond the parenchyma of the prostate before operation. There were no operative deaths.


Leg cramps (systremma0 and "restless legs" syndrome. Response to vitamin E (tocopherol). A clinical investigation into the therapeutic value of vitamin E (tocopherol) in certain dermatological conditions of obscure etiology led to the incidental observation that this compound produced beneficial effects in some of the patients who were suffering from frequent and severe nocturnal leg cramps. Nearly all of the patients with leg cramps received prompt and gratifying relief from their symptoms while taking vitamin E in the form of d, alpha-tocopheryl acetate, 100 I.U. three times a day before meals. The group included 24 private patients with leg cramps and two with the "restless legs" syndrome, probably a related condition. One of the patients with leg and foot cramps also had severe nocturnal rectal cramps which were also relieved. Nocturnal leg cramps constitute a relatively common complaint in the general practice of medicine and may be very distressing to the patient. Not only is the cause obscure and the treatment relatively unsatisfactory, but even its proper medical name, systremma (anything twisted up together), is unknown to most physicians.


Sublingual dermoid tumors.

Sublingual dermoid tumors.


The physical working capacity of blind and deaf school children.


Cell and tissue damage through antigen-antibody complexes.


Effects of high temperature and acute diuresis on glucose-6-phosphate dehydrogenase activity of mascula densa and plasma renin activity in rats.


Water intake of normal and desalivate rats on exposure to environmental heat.


Glass electrode measurement of ion transfers during rewarming of the single rat tail artery.


Some response characteristics of cells of the magnocellular division of the medial geniculate body of the cat.


Rate of release of amino acids from the cerebral cortex in the cat as affected by brainstem and thalamic stimulation.


On the delegation of responsibility ...

On the delegation of responsibility ...


Staff-line conflict in hospitals.

Staff-line conflict in hospitals.


Aging and learning.

Aging and learning.


Psoriasis--the stubborn malady.

Psoriasis--the stubborn malady.


The minis have it.

The minis have it.


Reaction of students who helped plan workshop at Queen's.


Two-year-old Michael--ill and in hospital.


Quality of care makes the difference.

Quality of care makes the difference.


The fluorescent properties of maturing arterial elastin.


Probabilistic characterization of R-R intervals.


Teen-age smoking in New Haven. I. Results of an in-depath survey.


The direct agglutination pregnancy (DAP) Test.


Electrocardiogram of the month.

Electrocardiogram of the month.


Heroin and public health.

Heroin and public health.


Electrophysiology of the intertectal commissures in the pigeon. I. Analysis of the pathways.


Electrophysiology of the intertectal commissures in the pigeon. II. Inhibitory interaction.


Cortical inhibition and gamma-aminobutyric acid.


Educational child care.

Educational child care.


Suicide in the hospital.

Suicide in the hospital.


Spinal injury unit.

Spinal injury unit.


Civil disturbance.

Civil disturbance.


Microbiological contamination control in hospitals. 3. Role of nursing service.


Nursing personnel show preference for carpeting.


Building a computer-assisted nutrient file.


Needed better pharmacy service. 2. The need in nursing homes.


Evaluation of computer-assisted management of the dietary department.


Trophoblastic tumours. I. Hydatidiform mole (review based on a study of 135 cases).


Disaccharidases in jejunal and ileal mucosa in Indian subjects.


Antibiogram of Staphylococcus pyogenes and some gram negative bacteria isolated in a large hospital.


The sensitivity of a Yoshida sarcoma to methylene dimethane sulphonate.


Effect of centrally acting drugs on the web building activity of a new species of an Indian spider. A preliminary report.


Serum alpha-1 foeto-protein (fetuin) in children with malignant ovarian or testicular teratomas. Preliminary results.


Continuous production of avian sarcoma virus B77 by rat tumour cells in tissue culture.


A reinvestigation of the origin of cells in grafted tumours, using the mouse T6 marker chromosome.


A mathematical model for the age distribution of cancer in man.


Editorial: folic acid.

Editorial: folic acid.


The haemopoietic factors associated with megaloblastosis.


Studies in neurological structure. 8. Excitor-depressor systems.


Failure of surface potential to influence thrombus formation.


The effect of oral ammonium chloride on the urinary excretion of calcium, magnesium and sodium in man.


Thyroid, tetany and trophic syndromes.

Thyroid, tetany and trophic syndromes.


Spontaneous Nosema cuniculi infection in laboratory rabbits.


Experimental use of animals by secondary school students.


Correlation between the anti-animal and anti-plant-virus activities of several antibiotics. (Studies on antiviral and antitumor antibiotics. XIX).


Studi on siomycin. II. The composition and degradation products of siomycin A.


The normal external radial pulse and its variation with posture.


The normal external carotid pulse and the effect of posture.


Lipids and fibrinolytic activity in normal fasting human plasma.


Effect of hydrochlorothiazides on blood sugar level in diabetics and nondiabetics.


Neurological manifestations in diabetes.


Neurological complication after smallpox vaccination.


Treatment of 80 cases of iron deficiency anaemias by T. D. I. of iron dextran complex.


Endomyocardial fibrosis. Clinicopathological study of a case.


Marble bone disease in a family.

Marble bone disease in a family.


The Landry Gullain--Barre syndrome. Survey and clinical report of 45 cases.


Occult tuberculosis as a cause of P.U.O. in tropics.


Cryptococcosis. A case report.

Cryptococcosis. A case report.


Diffuse encephalo-myelitis--a complication of antirabic vaccination.


Paroxysmal ventricular tachycardia in normal persons.


Association of Friedreich's ataxia and peroneal muscular atrophy (familial ataxia with atrophy). Report of two cases.


Dehydroemetine oral tablets in amoebiasis.


Jaw winking phenomenon.

Jaw winking phenomenon.


Studies on total, free and ester cholesterols and total bilirubin in kwashiorkor.


In vivo discrimination of iron-59 and chromium-51..


On the reversibility of the pre-eclamptic renal lesion (a report of 5 cases).


Erythromycin stearate in intestinal amoebiasis.


Forensic micro-anatomical patterns of true neck bruises versus post-mortem artefacts simulating bruises.


The role of liver dysfunction in the occurrence of the neuropsychiatric side effects of ambilhar.


Effect of dipterex on the acetylcholine content and cholinesterase activity of the brain of male albino rats.


Clinical and pathological evaluation of SH 850 for contraception.


Ultrastructural development of nuclear bodies in lymphocytic cells of normal mouse lymph nodes.


Correlation of structure, speed of contraction, and total tension in fast and slow abdominal muscle fibers of the lobster (Homarus americanus).


The lactate dehydrogenase isozymes of twelve species of flatfish (Heterosomata).


Modification of excitation-contraction coupling in locust skeletal muscle induced by caffeine.


Aster-equatorial surface relations and furrow establishment.


Lactate dehydrogenase isozymes of the flatfish, Pleuronectiformes: kinetic, molecular and immunochemical analysis.


Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons. Several analogues of the tetraethylammonium (TEA(+)) ion were injected into the giant axon of the squid, and the resultant changes in time course and magnitude of the potassium current (I(K)) were studied. For all the analogues used, three of the ethyl side chains of TEA(+) were left unchanged, while the fourth chain was either lengthened or shortened. Increasing the length of this chain increased binding to the blocking site in the channel by a factor of roughly two for each added CH(2) group. The effect on the rate of entry into the blocking site was relatively slight. Thus the concentration for half-suppression of g(K) decreased by about the same factor of two for each added CH(2). All the analogues caused anomalous or ingoing rectification. The longest chain analogue used, pentyltriethylammonium ion, caused rapid inactivation of g(K), and this inactivation had properties quite similar to g(Na) inactivation. The anomalous rectification and the g(K) inactivation caused by these compounds have the same basic mechanism.


The effect of ouabain and external potassium on the ion transport of rabbit red cells. Na efflux of rabbit RBC is approximately 10 mmoles/kg wet weight. hr. One-half of this consists of a ouabain-insensitive exchange diffusion component. Ouabain inhibits 2.5 mmoles/kg.hr of Na efflux. K influx is 3.0 mmoles/kg.hr; 2.2 mmoles/kg.hr are inhibited by ouabain. In contrast with human RBC, ouabain inhibition of Na efflux and K influx of rabbit RBC is easily reversible. After 2 hr, ouabain inhibition of Na efflux is completely compensated for by increased internal Na concentration and Na efflux returns to initial levels. Removal of ouabain at this stage results in stimulation of the efflux by 4.3 mmoles/kg.hr. Na influx is initially not affected by ouabain but is increased by 2.4 mmoles/kg.hr after 2 hr incubation with the drug. Removal of K from normal Ringer does not affect Na efflux and increases Na influx by 1.6 mmoles/kg.hr. Addition of ouabain to K-free Ringer inhibits Na efflux and influx to the same extent (1.6 mmoles/kg.hr). Removal of Na from K-free Ringer has an inhibitory effect on efflux similar to that of ouabain. These findings suggest that the fraction of Na efflux inhibited by removal of external K is completely replaced by a new, ouabain-sensitive exchange diffusion of Na ions.


The effects of external potassium and long duration voltage conditioning on the amplitude of sodium currents in the giant axon of the squid, Loligo pealei. Giant axons were voltage-clamped in solutions of constant sodium concentration (230 mM) and variable potassium concentrations (from 0 to 210 mM). The values of the peak initial transient current, I(p), were measured as a function of conditioning prepulse duration over the range from less than 1 msec to over 3 min. Prepulse amplitudes were varied from E(m) = -20 mv to E(m) = -160 mv. The attenuation of the I(p) values in high [K(o)] was found to vary as a function of time when long duration conditioning potentials were applied. In both high and low [K(o)], I(p) values which had reached a quasi-steady-state level within a few milliseconds following a few milliseconds of hyperpolarization were found to increase following longer hyperpolarization. A second plateau was reached with a time constant of about 100-500 msec and a third with a time constant in the range of 30 to 200 sec. The intermediate quasi-steady-state level was absent in K-free ASW solutions. Sodium inactivation curves, normalized to I(pmax) values obtained at either the first or second plateaus, were significantly different in different [K(o)]. The inactivation curves, however, tended to superpose after about 1 min of hyperpolarizing conditioning. The time courses and magnitudes of the intermediate and very slow sodium conductance restorations induced by long hyperpolarizing pulses are in agreement with those predicted from the calculated rates and magnitudes of [K(+)] depletion in the space between the axolemma and the Schwann layer.


The spectral sensitivities of single cells in the median ocellus of Limulus. The spectral sensitivities of single Limulus median ocellus photoreceptors have been determined from records of receptor potentials obtained using intracellular microelectrodes. One class of receptors, called UV cells (ultraviolet cells), depolarizes to near-UV light and is maximally sensitive at 360 nm; a Dartnall template fits the spectral sensitivity curve. A second class of receptors, called visible cells, depolarizes to visible light; the spectral sensitivity curve is fit by a Dartnall template with lambda(max) at 530 nm. Dark-adapted UV cells are about 2 log units more sensitive than dark-adapted visible cells. UV cells respond with a small hyperpolarization to visible light and the spectral sensitivity curve for this hyperpolarization peaks at 525-550 nm. Visible cells respond with a small hyperpolarization to UV light, and the spectral sensitivity curve for this response peaks at 350-375 nm. Rarely, a double-peaked (360 and 530 nm) spectral sensitivity curve is obtained; two photopigments are involved, as revealed by chromatic adaptation experiments. Thus there may be a small third class of receptor cells containing two photopigments.


Two components of the cardiac action potential. I. Voltage-time course and the effect of acetylcholine on atrial and nodal cells of the rabbit heart. Transmembrane potentials recorded from the rabbit heart in vitro were displayed as voltage against time (V, t display), and dV/dt against voltage (V, V or phase-plane display). Acetylcholine was applied to the recording site by means of a hydraulic system. Results showed that (a) differences in time course of action potential upstroke can be explained in terms of the relative magnitude of fast and slow phases of depolarization; (b) acetylcholine is capable of depressing the slow phase of depolarization as well as the plateau of the action potential; and (c) action potentials from nodal (SA and AV) cells seem to lack the initial fast phase. These results were construed to support a two-component hypothesis for cardiac electrogenesis. The hypothesis states that cardiac action potentials are composed of two distinct and physiologically separable "components" which result from discrete mechanisms. An initial fast component is a sodium spike similar to that of squid nerve. The slow component, which accounts for both a slow depolarization during phase 0 and the plateau, probably is dependent on the properties of a slow inward current having a positive equilibrium potential, coupled to a decrease in the resting potassium conductance. According to the hypothesis, SA and AV nodal action potentials are due entirely or almost entirely to the slow component and can therefore be expected to exhibit unique electrophysiological and pharmacological properties.


The influence of potassium- and sodium-free solutions on sodium efflux from squid giant axons. The sensitivity of sodium efflux to the removal of potassium ions from the external solution and the change in sodium efflux occurring when sodium ions are also removed were observed to be related. When Tris was used to replace external sodium ions, increases in sodium efflux were always observed whether the sensitivity of sodium efflux to external potassium ions was weak or strong. Greater percentage increases in sodium efflux occurred, however, the greater the sensitivity of sodium efflux to external potassium ions. When lithium ions were used to replace external sodium ions, increases in sodium efflux occurred if the sensitivity of efflux to external potassium ions was strong whereas decreases in sodium efflux took place if the sensitivity of efflux to external potassium ions was weak. Intermediate sensitivities of efflux to external potassium resulted in no change in efflux upon substitution of lithium ions for external sodium ions. In the presence of 10(-5)M ouabain, substitution of Tris for external sodium ions always resulted in a small decrease in sodium efflux. The data can be described in terms of a model which assumes the presence of efflux stimulation sites that are about 98% selective to potassium ions and about 2% selective to sodium or lithium ions.


The relationship between cell membrane potassium ion transport and glycolysis. The effect of ethacrynic acid. Cell membrane transport of K(+) stimulates the rate of glycolysis in Ehrlich ascites tumor cells. A study of the characteristics of this relationship indicates that the stimulation occurs under anaerobic as well as under aerobic conditions. The data suggest that glycolysis is stimulated by a K(+) transport mechanism that is coupled to Na(+) transport because the effect is blunted or abolished when the principal intracellular ion is lithium or choline. This stimulus to glycolysis is blocked by ouabain and ethacrynic acid, agents that have been shown to inhibit monovalent cation transport in erythrocytes. In contrast to the action of ouabain, glycolysis is inhibited by ethacrynic acid in Ehrlich ascites tumor cells in the absence of cell membrane K(+) transport. In studies with ghost-free hemolysates of human erythrocytes and with cytosol prepared from Ehrlich ascites tumor cells, ethacrynic acid significantly blocks lactate formation from fructose diphosphate demonstrating the direct inhibitory effect of this agent on one or more enzymes of the Embden-Meyerhof pathway. Since ethacrynic acid has no influence on lactate formation in intact erythrocytes utilizing an endogenous substrate, the presumptive site of inhibition is proximal to the 3-phosphoglycerate level.


Pacemaker electrocardiography. (II).

Pacemaker electrocardiography. (II).


Studies on the serum therapy of type E botulism. II.


Primary immunization of infants and children with group A streptococcal M protein.


The effect of calorie and protein malnutrition on both the parasite and the host in acute murine schistosomiasis mansoni.


Trends in meningococcal disease.

Trends in meningococcal disease.


Germfree research at the NIH.

Germfree research at the NIH.


New test for congenital infections.

New test for congenital infections.


White House Conference on Food, Nutrition, and Health, December 2-4, 1969, Washington, D. C.


Serum antigens in viral hepatitis.

Serum antigens in viral hepatitis.


Increases in skeletal calcium and femur cortex thickness produced by undernutrition.


Changes in plasma proteins associated with the anemia produced by dietary cadmium in Japanese quail.


Vitamin A activity of corn carotenes for swine.


A study of the relative potency of L- and D-thyroxine in preventing kidney calcification associated with magnesium deficiency.


Regional renal adenosine triphosphate metabolism in thiamine deficiency.


Effect of dietary molybdenum and sulfate upon copper metabolism in sheep.


Effect of cold exposure on the response of rats to a dietary amino acid imbalance.


Vitamin E deficiency and fat stress in the dog.


Influence of dietary carbohydrate on duodenal lesions in the mouse.


Relation between the lumen-blood electrochemical potential difference of calcium, calcium absorption and calcium-binding protein in the intestine of the fowl.


Sodium metabolism and its requirement during reproduction in female rats.


Master and apprentice.

Master and apprentice.


The solitary thyroid nodule.

The solitary thyroid nodule.


I. The thyroid. Epidemiology of thyroid cancer.


II. The colon. The pharmacology of colonic muscle.


Ulcerative colitis and carcinoma of the colon.


The radiological detection of early carcinoma and pre-malignant lesions of the colon and rectum.


A study of large bowel peristalsis in man.


Intrahepatic choledochus cyst.

Intrahepatic choledochus cyst.


Postoperative abdominal support.

Postoperative abdominal support.


Congenital complete heart block in newborns, infants, children and adults.


Critical complications in patients with cancer: prevention and treatment.


The importance of circulating antibody in human disease.


Convulsive disorders. A working classification and guideline for diagnosis and treatment.


Arteriographic diagnosis of thoracic outlet syndromes. Improved surgical results of corrective procedures selected on basis of arteriographic studies.


Chylous mesenteric cyst. Case report.

Chylous mesenteric cyst. Case report.


Mitral stenosis--how not to miss it. With emphasis on the "White Bear" syndrome.


Dialysis and the surgical patient.

Dialysis and the surgical patient.


Ultrasound treatment in diseases of the locomotor system.


Diuretics in renal disease.

Diuretics in renal disease.


Primam non nocere.

Primam non nocere.


Two minutes with diabetes.

Two minutes with diabetes.


Inservice training for non-professional personnel in a mental retardation center.


The integration of the mentally retarded and non-retarded in a day camping program. A demonstration project.


Criteria for priority admission to state residential facilities for the mentally retarded.


Project: service through inservice.

Project: service through inservice.


Heterosexual and aggressive behaviors among institutionalized retardates.


Social changes, minorities, and the mentally retarded.


The transfer of adult mental retardates from a state hospital to nursing homes.


Emerging curricula for the elementary level educable mentally retarded.


Family therapy: its use in mental retardation.


The emergency role of the residential facility in the treatment & care of the community retardate.


More ado about operant conditioning--or nothing?


Program profiles. Group therapy as an instrument to develop a concept of self-worth in the adolescent and young adult mentally retarded.


Special education for the mentally retarded in Japan.


QT prolongation and sudden death.

QT prolongation and sudden death.


The U wave of the electrocardiogram.

The U wave of the electrocardiogram.


Rationale and limitations of hemodynamic measurements in patients with acute myocardial infarction.


Echocardiography.

Echocardiography.


Lesions in swine inoculated with attenuated hog cholera viruses.


Hydrogen ion and the activation of electrically excitable membranes.


High resolution proton magnetic resonance studies of fully deuterated and isotope hybrid proteins.


Occurrence of fatty acids and aliphatic hydrocarbons in a 3-4 billion-year-old sediment.


Structure of ferroverdin.

Structure of ferroverdin.


Relationship between absorption spectrum and molecular conformations of 11-cis-retinal.


Physicochemical studies of L-asparaginase from Erwinia carotovora.


Glucose-6-phosphate dehydrogenase mosaicism for studying the development of blood cell precursors.


Does hydroxyurea inhibit chromosome repair in cultured human lymphocytes?


Isolation and growth of mycoplasma in human embryo trachea cultures.


Time course of rat brain GABA levels following methionine sulphoximine treatment.


Possible basis for the evolution of lateral specialization of the human brain.


Fluid mechanics of the mitral valve.

Fluid mechanics of the mitral valve.


DDT in Antarctic snow.

DDT in Antarctic snow.


Radiobiological terminology.

Radiobiological terminology.


Incomplete labeling of prescriptions by pharmacists.


Survey of existing services and facilities for the epileptic in the state of Oregon.


Prognostic value of serum creatine phosphokinase levels in myocardial infarction.


Malady in G. The Chinese restaurant signdrome.


The meaning of family medicine.

The meaning of family medicine.


Reactive depression in a case of muscular dystrophy.


Royal occasion at Nocton Hall.

Royal occasion at Nocton Hall.


Teenage hypercalcaemia.

Teenage hypercalcaemia.


Surgery in rheumatoid arthritis. 1.

Surgery in rheumatoid arthritis. 1.


Toronto's Scarborough General Hospital.

Toronto's Scarborough General Hospital.


Progress in programmed instruction.

Progress in programmed instruction.


Rubella--a light-hearted case history.

Rubella--a light-hearted case history.


Surgery in rheumatoid arthritis. 2.

Surgery in rheumatoid arthritis. 2.


Occupational therapy and the nurse. 1.

Occupational therapy and the nurse. 1.


Mental disorders in the elderly.

Mental disorders in the elderly.


The Croydon Volunteer Aid Project.

The Croydon Volunteer Aid Project.


Modern trends in general practice. A quiet revolution.


Diagnostic lung puncture.

Diagnostic lung puncture.


Antibiotic treatment of pertussis.

Antibiotic treatment of pertussis.


Acute hemangioma-like lesions associated with ECHO viral infections.


Sympathomimetic drugs in acute viral bronchiolitis. Their effect on pulmonary resistance.


Dexamethasone in the treatment of acute bacterial meningitis: the effect of study design on the interpretation of results.


Tuberculous meningitis developing during the course of chemotherapy for pulmonary tuberculosis.


The preschool intelligence of oversized newborns.


Rectal thermometer-induced pneumoperitoneum in the newborn. Report of two cases.


The adsorption of bilirubin by Sephadex and its relationship to the criteria for exchange transfusion.


Hyperprolinemia: clinical and biochemical family study.


Rieger's syndrome.

Rieger's syndrome.


Congenital asymmetry: report of 10 cases with associated developmental abnormalities.


Neuronal ceroid-lipofuscinosis (Batten's disease): relationship to amaurotic family idiocy?


Diagnosis and treatment: dyslexia.

Diagnosis and treatment: dyslexia.


Child abuse syndrome: the "gray areas" in extablishing a diagnosis.


The pediatric convalescence hospital.

The pediatric convalescence hospital.


Transient left bundle branch block in a neonate.


Prognosis of childhood leukemia.

Prognosis of childhood leukemia.


The XYY condition in childhood: clinical observation.


Salt-losing congenital adrenal hyperplasia.


Stage O carcinoma of the cervix. A twenty-one year survey.


Occupational hazards to physicians--suicide.


On doctors and title XIX.

On doctors and title XIX.


The coronary care unit and arrhythmias complicating myocardial infarction. I.


Reach to Recovery Program. I.

Reach to Recovery Program. I.


Absolute values of photon emission from the marine dinoflagellates Pyrodinium bahamense, Gonyaulax polyedra and Pyrocystis lunula.


The photochromism of the dehydrodianthrones. Pariser-Parr-Pople calculations.


Transfer of energy from reaction center to light harvesting chlorophyll in a photosynthetic bacterium.


Photoinhibition of growth of a yellow and colorless form of Chlamydomonas reinhardtii.


Stabilization of semiquinone intermediates in the photoreduction of phenanthrenequinone by complex formation.


Chemical filters for narrow band U.V. irradiation between 235 and 300 nm.


Diffuse spectral reflectance modification of skin by U.V. irradiation.


Physiology of the distal esophagus in achalasia.


The effect of unabsorbed sucrose- or mannitol-induced accelerated transit on absorption in the human small intestine.


A study of the gastro-secretagogue power of urine (P. S. U.) before and after portacaval anastomosis in man.


Experimental acute pancreatitis in dogs. 3. The nature of the phospholipase activity of pancreatic exudate.


Action of Histalog on the secretion of sulfated glycoproteins in the human stomach.


Effect of tolbutamide on the dumping syndrome.


The functional state of the gastrointestinal tract before and after selective surgery.


The production of acute gastric ulceration by indomethacin in the rat.


Absorption of acetylsalicylic acid b a normal and an atrophic gastic mucosa.


Body building for mental health.

Body building for mental health.


Studies of gastrointestinal function in amyloidosis f familial Mediterranean fever.


Rehabilitation of the forgotten cleft child.


A preview of the migrant as a rehab client.


Studies on the mechanism of te antrectomy-inced suppression of the maximal acid response to histamine in duodenal ulcer patients.


Correlation analysis of duodenal aspirates after secretin administration.


Acid base changes due to secretin administration in normal patients and in patients with pancreatic disease.


The steatorrhoea of chronic liver disease without jaundice.


The relationship between the gastric and pancreatic secretion in man.


Diagnosis of lactose malabsorption by the lactose tolerance test with peroral ethanol administration.


A screening technique for the detection of achlorhydria using the Heidelberg capsule.


Specific small-intestinal lactase deficiency in adults.


The vicissitudes of change.

The vicissitudes of change.


Medical organization, medical care and lower income groups.


Sex reannouncement in hereditary sex deformity: psychology and sociology of habilitation.


Nurses, professional striving and the poor--a case of incompatibility.


Cultural deprivation, lower class and mental retardation: certain terminological and conceptual confusions.


Labeling and psychiatry: perspectives in need of data.


General practitioners' attitudes towards group practice in the Netherlands.


Effect of ionizing radiation on tryptophan oxygenase of rat liver.


Reproductive performance of Wistar rat following internal Co60 irradiation at low dose levels.


Staphylocoagulase as a hemostatic agent.


Federal support of education and research: policy issues and national needs.


Door-to-door canvassing as a means of family planning patient recruitment.


Enzymic, ATP-Dependent cleavage of beta-methyl-delta-keto-delta(alpha beta)-hexenoic acid. I. Beta-methyl-delta-keto-delta(alpha beta)-hexenoic acid as acetyl donor.


The reaction of sulfhydryl groups of dehydrogenases with iodine.


Studies on the mechanism of the effect of trypsin on the shape maintenance of erythrocytes.


Longitudinal structure of the striated fibril.


Transversal structure of the striated fibril.


Development of media suitable for dose measurement. Dose measurement media.


The use and comparative study of dose measurement media in animal experiments. Various media in animal irradiations.


Effect of radioactive radiations on the lifetime of sperms.


Photoreduction of chlorophyll b in the presence of benzylamine.


Quantitative chromatography of aromatic amino acids on Sephadex G-10.


Synthesis of arginine from citrulline and aspartate in preparations from wheat sprouts.


Studies on ox-brain arginase.

Studies on ox-brain arginase.


The formation of UDP-glucose and UDP-galactose in wild type and mutants of Aspergillus nidulans.


Utilization of 14C-labelled purine precursors for uric acid synthesis in Helix pomatia.


Preparation and properties of N4-alkyl analogues of 5-methyl-2'-deoxycytidine, their 5'-mono- and triphosphates, and N4-alkyl derivatives of 1,5-dimethylcytosine.


Mechanism of hydroxylamine mutagenesis: complexing properties of copolymers of hydroxycytidylic acid with cytidylic or uridylic acids.


The nature of the litter size loss in senescent hamsters.


Ovarian morphological and functional changes in reproductively senescent hamsters.


Age changes in the cranial base of the rabbit (Oryctolagus cuniculus).


H3-leucine incorporation in antigenically stimulated rat popliteal lymph node cells.


Changes in coronary arteries of mice fed a high-fat, low-protein diet followed by a normal diet.


Responses of fatty livers of mice of carbon tetrachloride.


Electromyography of genioglossus and geniohyoid muscles during deglutition.


The placenta of the four-eye opossum (Philander opossum).


Chorioretinal changes, juxtapapillary staphyloma, and retinal detachment in the collie.


The axial length of the eye of normal subjects and of patients with retinal detachment.


Photoelastic and ultrasonic studies on the structure and senile changes of the intervertebral disc and of the vitreous body.


Retinal detachment in children: surgical experience.


The role of trauma in juvenile retinal detachment.


Retinal detachment in juveniles (ages 1 to 20 years).


Retinal detachments in children.

Retinal detachments in children.


Juvenile retinal detachment at the Barraquer Clinic.


Juvenile detachment in Denmark.

Juvenile detachment in Denmark.


Juvenile retinal detachment.

Juvenile retinal detachment.


Survey of statistics on juvenile detachment.


Juvenile sex-linked retinoschisis.

Juvenile sex-linked retinoschisis.


Three brothers with juvenile retinoschisis.


Rhegmatogenous retinal detachment in premature twins.


A method for measuring the relative strengths of induced chorio-retinal adhesions.


The cryosurgical adhesion.

The cryosurgical adhesion.


Cooling of the sclera in diathermal coagulation.


Retinal detachment surgery; a comparison of diathermy and cryosurgery.


Significance of pigment dispersion following cryoretinopexy: scotomata and atrophy.


Diabetic retinopathy and photocoagulation.


Photocoagulation in diabetic retinopathy.


Surgery of advanced diabetic retinopathy.


Experimental detachment of the retina and its effect on the intraocular fluid dynamics.


Silicone injection in retinal detachment.


The prevention of aphakic detachment by a method of extraction designed for the purpose and the prevention of myopic detachment by contact lenses.


Treatment of retinoblastoma with cryopexy; a follow-up report.


Lamellar undermining, diathermy and tissue transplantation versus cryotherapy and full-thickness scleral buckling.


Remote screw-type syringe for intra-vitreous injection.


Chronic bronchitis, smoking and social class. A study among working people in the towns of Mid and East Cheshire.


Endobronchial chondroma presenting as asthma.


Cervical herpes zoster and diaphragmatic paralysis.


The effect of arvin on experimental pulmonary embolism in the rabbit.


Fibrinolysis at rest and after exercise in hepatic cirrhosis.


Mechanism of enhanced streptokinase-induced clot lysis following in-vitro factor-XIII inactivation.


Electron microscopy of fibrin-like precipitate formed during the paracoagulation reaction between soluble fibrin monomer complexes and protamine sulphate.


Erythropoiesis, red-cell creatine and plasma aldolase activity in anaemia in the rabbit and man.


Haemoglobin synthesis in beta-thalassaemia.


Immunochemical quantitation of human transferrin in pregnancy and during the administration of oral contraceptives.


Constitutional differences between men recruited for driving and non-driving occupations.


Validation of death certificates in asbestos workers.


A study of the mortality of workers in an asbestos factory.


A population study in cotton ginnery workers in the Sudan.


Exposure of spray operators to paraquat.


Effects of carbon disulphide on the liver of rats.


Dieldrin poisoning in dogs: relation to obesity and treatment.


The kinetics of the autoxidation of ferrous ions in aqueous tripolyphosphate solutions.


Temperature-jump studies of the kinetics of the formation of the monochloro and monobromo complexes of iron. 3.


Spectrophotometric determination of L-ascorbic acid.


Kinetic studies of the triethylenediamine-catalyzed transamidation of 1,3-diphenylurea with n-butylamine in dioxane.


Studies on cow's urine. V. Determination by gas-liquid chromatography of an acidic part obtained from cow's urine (supplement).


Positive expiratory pressure plateau: improved gas exchange during mechanical ventilation.


A clinical appraisal of the adequacy of brain circulation during anaesthesia (with particular reference to carotid thromboendarterectomy).


Experimental observations on propranolol in anaesthesia.


Canadian hospital bans flammable anesthetics for safety's sake.


Influence of enzyme induction on the sleeping time of rats.


Whole-body metabolism during and after abdominal surgery.


Veterinarians and physicians collaborate.


Effects of cold acclimation and arousal from hibernation on brown fat lipid and protein in the golden hamster (Mesocricetus auratus).


Differences in the chromium51-labelling patterns of cod (Gadus callarias) and human blood.


The lipids of some lantern fishes (family Myctophidae).


Quaternary structure of the radular muscle myoglobin of the gastropod mollusc Buccinum undatum L.


Glycerokinase and desaturase activity in pig, chicken and sheep intestinal epithelium.


Seven-minute rhythms in stable avoidance conditioning.


Isocitrate dehydrogenase activity of serum in experimental kidney damage.


Changing lactate dehydrogenase isoenzyme pattern in the ageing erythrocyte.


Effect of streptomycin on urate oxidase activity.


Conditional reflexes and sensory-evoked epilepsy: the nature of the therapeutic process.


Influence of subcellular RNA fractions of rat livers of normal, fasted and re-fed, and actinomycin treated animals, on the amino acid incorporation in vitro.


Ultrastructural studies on normal and leukaemic human haematopoietic cells.


Carcinoma of the colon in a rat.

Carcinoma of the colon in a rat.


Pharmaco-biochemical studies on cytotoxic polyol derivates. I. Effects of 1-6-dibromo-1-6-dideoxy-dulcitol on sensitive, resistant and refractor tumours.


Development of a vertebrate experimental model for cellular neurophysiologic studies of learning.


Hypercalcemia associated with vulvar carcinoma.


Growth pattern of normal infants in Varanasi (U. P.) India.


Encephalitis in children. A clinical study of 409 cases.


45,X-46,XX mosaicism in Turner's syndrome.


Disappearance of infectious virus from Friend Virus-induced C57BL-6 tumors.


Aflatoxin carcinogenesis: inhibition of liver cancer induction in hypophysectomized rats.


A spleen weight assay for Murine Sarcoma Virus Harvey (MSV-H).


Effect of age and sex on the development of neoplasms in wistar rats receiving a single intragastric instillation of 7,13-Dimethylbenz(a)anthracene.


Large- and small-plaque variants of oncogenic Simian Adenovirus SA7(C8).


Cytotoxicity of sera from healthy persons and cancer patients.


Intraperitoneal introduction of tantalum powder. A roentgenographic and pathologic study.


Clinical limitations to use of xenon for measurement of myocardial blood flow.


Angiography with direct fourfold magnification.


Effect of graded osmolalities of saline solution and contrast media on renal extraction of PAH in the dog.


Determination of focal-spot characteristics of microfocus x-ray tubes.


Does renal blood flow rise or fall in response to diatrizoate?


Benemid in intravenous cholangiography. Clinical evaluation.


Studies on the function of ribonuclease inhibitor in rat liver.


Circular dischroism of Japanese-radish peroxidase a.


Fistula between bowel and urinary tract.


Diagnosis of meningioma by radioisotopic and thermal scans.


Obturator obstruction of the intestine: report of two unusual cases.


Isolation and analysis of glycopeptides from polymorphic variants of alpha 1-acid glycoprotein of human plasma.


Transluminally-placed coilspring endarterial tube grafts. Long-term patency in canine popliteal artery.


Hypsarrhythmia accompanying tetany of the newborn.


Arteriographic diagnosis of acute pancreatitis.


Radiodermatography. Simultaneous demonstration of dermatoglyphics and osseous structures in the hand.


Pacemaker electrocardiography (3).

Pacemaker electrocardiography (3).


Exacerbation of spontaneously occurring arteriosclerosis in breeder rats following chronic treatment with cortisone.


The Katherine Hamilton Mental Health Center.


Tyrannical taxation.

Tyrannical taxation.


Lipid accretion in the perfused rabbit aorta.


The dependence of post-reproduction arteriopathy in rats on diet.


Carbon monoxide intoxication and poisoning.


The modified rapid-sequence urogram as a screening test for renovascular hypertension.


Pattern of vessel involvement in cerebral atherosclerosis. A comparative study between a Japanese and Minnesota population.


Macrodactyly.

Macrodactyly.


The pediatric aspects of atherosclerosis.


Some reflections on surgery and surgeons.


The effect of modified beta-lipoproteins on adhesiveness and on aggregation of blood platelets.


Which billing system?

Which billing system?


Method of inspecting the jugular veins.

Method of inspecting the jugular veins.


Group practice.

Group practice.


Recent trends in acute coronary care.

Recent trends in acute coronary care.


A review of 56 abdominal aortic aneurysms.


Ischaemic heart disease in a general practice.


The future of medical education in Dublin.


Multiple injuries.

Multiple injuries.


Oak Ridge Institute and nuclear medical technology.


The management of behavior disorders with thioridazine in the mentally retarded.


X-ray of the monh.

X-ray of the monh.


The epidemiology of infectious syphilis.


How to help your patient stop smoking.

How to help your patient stop smoking.


Acute blood levels of lidocaine following paracervical block.


Carpal tunnel syndrome--diagnosis and management.


Experiences with the use of flurandrenolone tape in dermatology.


One medical community's fight against cancer--"Savannah".


Coronary heart disease and smoking. A reducible risk factor.


Neural servosystems and the structure of personality.


Limbic encephalitis.

Limbic encephalitis.


A histopathological study on the distribution of tissue mast cells in human uterine cervix and stomach.


Comparative studies of the adrenergic relaxations in the excised jejunum of rat, evoked by nicotine, tyramine, histamine, calcium and transmural stimulation; with a special reference to the catecholamine release.


An inborn error of cerebroside biosynthesis as the molecular defect of the Jimpy mouse brain.


The coagulation of blood: preliminary survey of thrombin and autoprothrombin zymogen structure.


Citrate synthase of bean seedlings--comparison of activity following in vitro and in vivo treatments of enzyme.


Binding of sugars to isolated brush borders.


Preliminary results of erythropoietin production by bovine kidney cells in culture.


Macromolecular interactions in organic solvents.


Further studies on RNA fractions from normal and crown gall tumor tissue cultures of tobacco.


Isolation and characterization of a novel nucleoside, N-[(9-beta-D-ribofuranosyl-9H-purin-6-yl)carbamoyl]threonine, from human urine.


Hydrolysis of cholesteryl oleate in vitro by ovarian homogenates from non-pregnant and pregnant rabbits.


Dermatology in Minnesota.

Dermatology in Minnesota.


Treatment of coronary disease--pathologic limitations.


Suicide and related clinical problems.

Suicide and related clinical problems.


Thrombocytosis. A clinical evaluation of 322 patients.


Tussive syncope.

Tussive syncope.


Hematologic toxicity of chloramphenicol.


Malignant tumors in children.

Malignant tumors in children.


Electronic pacemakers.

Electronic pacemakers.


Post-intubation granuloma of the larynx.


Corrective surgery in elderly patients: a dilemma.


Vaginal hysterectomy.

Vaginal hysterectomy.


Curbstone consultation.

Curbstone consultation.


Weakness and backache.

Weakness and backache.


Problems in initial treatment of multiple fractures.


Corrosive esophagitis. Acute management with a case report of early surgical intervention.


Cutaneous biopsy.

Cutaneous biopsy.


Hypercalcemia associated with non-parathyroid tumors.


"Normal ranges" and aging.

"Normal ranges" and aging.


Tumors in infancy and childhood.

Tumors in infancy and childhood.


Splitting of the atrial sounds.

Splitting of the atrial sounds.


The differential diagnosis of sudden cerebral deficit.


Radioisotope encephalography and brain tumors.


The place of radiotherapy in the treatment of bronchogenic carcinoma.


Congenital nasolacrymal duct obstruction in infancy.


A new application of ultrasono-tomography in the region of radiotherapy and its clinical significance. I. Ultrasono-tomogram of tumor in radiotherapy.


On plasmocytoma oncogenesis of mice. 3. Annulate lamellae with unusual morphology in a plasmocytoid neoplasia of mice (HIPA tumor).


On the size and biological properties of mycoplasma. Minimal reproductive units.


Biochemical activity of coagulase positive Staphylococci isolated from cases and carriers.


Freeze-etch appearance of the tight junctions in the epithelium of small and large intestine of mice.


Extracellular and intracellular chemical environments in relation to embryogenesis in vitro.


Augmentation and dispersion of the in vivo mitotic apparatus of living marine eggs.


Differences in response to colchicine by differentiating xylem cells in roots of Pisum.


Psychoanalytic considerations of language and thought. A comparative study.


Pathological jealousy.

Pathological jealousy.


A note on "the pill" and emotional conflict.


Errors and error detection in typing.

Errors and error detection in typing.


The effect of object familiarity on the perception of size and distance.


Using several modalities to perceive one temporal pattern.


Some evidence for parallel comparisons in a letter recognition task.


Syntactic structure modifies attention during speech perception and recognition.


The non-reactive type of low-voltage EEG.


The operation: a fundamental aspect of nervous function.


Some characteristics of the early components of the somato-sensory evoked response to mechanical stimuli in man.


Transient global amnesia.

Transient global amnesia.


Electrocardiographic changes in intracranial expanding processes.


Pseudodementia as initial syndrome in obscure brain disease.


Electron microscopic studies on the rebral lesions of rats in experimental carbon monoxide poisoning.


Sodium localization in the adult brain. II. Triethyltin intoxication and cerebral edema produced by epidural compression.


Predominantly cerebral forms of histiocytosis-X. A reappraisal of "Gagel's hypothalamic granuloma", "granuloma infiltrans of the hypothalamus" and "Ayala's disease" with a report of four cases.


Femoral-popliteal venous thrombosis and pulmonary embolism.


Indirect methods for estimating the normal range.


An automatic instrument for the measurement of hemoglobin concentration.


Plasma fibrin-stabilizing factor: acquired deficiency in various disorders.


Assay for erythrocyte adenosine monophosphate deaminase (AMP aminohydrolase, EC 3.5.4.6) and effects of certain blood preservatives on this enzyme.


Spurious hypocalcemia in patients undergoing maintenance hemodialysis.


Errors of converting a urine alcohol value into a blood alcohol level.


Slide rule for the evaluation of compensation in primary metabolic or respiratory acidosis.


The pathologic changes associated with the intravenous use of Sephadex.


Benign rhabdomyoma of the vagina.

Benign rhabdomyoma of the vagina.


Cytoplasmic lamellar inclusions resembling tissue mast cel granules in suspected rheumatoid lung disease.


The world of work in the 1970's.

The world of work in the 1970's.


Career ladders and equivalency examinations: what does it all mean?


Electron microscopical study of experimentally induced poisoning due to organic mercury compound. Mechanisof development of the morbid change.


Microinvasive carcinoma of the uterine cervix.


Pelizacus-Merzbacher disease. Transitional form between classical and co-natal (Seitelberger) type.


The 13q-deletion syndrome.

The 13q-deletion syndrome.


Contralateral spread of head and neck cncer.


Future of the head and neck cancer surgeon.


Factors influencing the safety of carotid ligation.


Cryosurgery for oral and pharyngeal carcinoma.


Carcinoma of the larynx, a retrospective study of 144 cases.


Treatment d survival in cancer of the cervical esophagus.


A simple technic for laryngeal suspension after partial or complete resection of the hyomandibular complex.


A patty-bear leg for amputation at the knee--or how to make a leg to fit a stump instead of a stump to fit a leg. 3.


Total lid resection with plastic repair.


Intra-articular osteochondroma. Report of a case.


Irradiation twenty-four hours preoperatively.


Three-year observation of combined treatment for far advanced cancer of the head and neck.


Treatment of advanced cancer ofhe head and neck with intensive preoperative irradiation and radical surgery.


Successful reimplantation of autogenous parathyroid tissue.


Carcinoma of the thyroid after external radiation to the neck in adults.


Craniofacial resection for tumors invading the pterygoid fossa.


Tongue flaps for intraoral reconstruction.


Free grafts of the spinal accessory nerve during radical neck dissection.


Spinal accessory nerve in radical neck dissections.


Squamous cell carcinoma of the maxillary antrum.


Hematologic values of burros from birth to maturity: cellular elements of peripheral blood.


Toxicologic effects of aerosols of N,N-diethyl-m-toluamide (deet) applied on skin of horses.


Effect of coumaphos and fenthion feed additives on gastrointestinal nematode egg counts in feedlot cattle.


Penetration of penicillin into the aqueous humor of the dog.


Clinical and serologic responses in dogs inoculated with the chlamydial (psittacosis) agent of ovine polyarthritis.


Values for plasma electrolytes, osmolality, and creatinine and venous PCO2 in normal sheep.


Cholelithiasis in rabbits: effects of several treatments on formation and dissolution of gallstones.


A partially defined (synthetic) medium for Mycoplasma gallisepticum.


A technique for pinealectomy of the ewe.


Regional distribution of cholinesterase in the central nervous system of miniature swine.


A new look at prosthetic materials.

A new look at prosthetic materials.


The place of antibiotics in surgical practice to-day.


Gynaecological aspects of the acute abdomen.


Oral glucose tolerance studies in recurrent Trichophyton rubrum infections.


Surgical training of dermatologists.

Surgical training of dermatologists.


Tympanic thermometry during anesthesia.

Tympanic thermometry during anesthesia.


Facial palsy in Hand-Schüller-Christian's disease.


Geniculate ganglion anatomy for the otologist.


Succinic dehydrogenase in the pigeon ampulla.


Sulfur metabolism in otosclerosis.

Sulfur metabolism in otosclerosis.


Sensorineural hearing loss associated with firearms.


Stapedial otosclerosis and fluorine in the drinking water.


Papillary cystadenoma lymphomatosum (Warthin's tumor); report of a case.


Facial nerve paralysis secondary to benign parotid tumor.


Infantile hemangioma of the parotid gland; a clinicopathological study of 15 cases.


Rhabdomyosarcoma of the ear; a cause for suppurative ear diseases in children.


Multiple sclerosis after x-radiation. Activation by treatment of metastatic glomus tumor.


Diminishing facial wrinkles by linear eversion.


Cricoid cartilage abnormalities.

Cricoid cartilage abnormalities.


Nasal spirometry; a volumetric study of nasal air flow capacity.


Malignant hyperthermia complicating general anesthesia.


Palatal stone.

Palatal stone.


Doctor in the courtroom.

Doctor in the courtroom.


A positive approach to the foreign pathology resident.


Granulomatous eosinophilic epicarditis in the newborn. Report of three cases.


Increased mitotic activity in aortas of swine after three days of cholesterol feeding.


Myocardial carbohydrate metabolism and lesions in hemorrhagic shock. Effects of hyperbaric oxygen.


Parathyroid cyst and cystic degeneration of parathyroid adenoma.


Mixed carcinoid and mucus-secreting intestinal tumors.


Dimensions of normal human hearts after standard fixation by controlled pressure coronary perfusion.


Bone formation in osteoporosis. Appositional rate measured by tetracycline labeling.


Histopathology of endotracheal intubation. An autopsy study of 99 cases.


Effect of spironolactone on the zona. Light and electron microscopy.


Origin of the lung macrophage. Evidence derived from radiation injury.


Two cases of coronary embolism following cardiac surgery.


Bilateral papillary cystadenomas of the lacrimal caruncle.


Persistent left vitelline vein entering right atrium.


Pseudolipoma of Glisson's capsule.

Pseudolipoma of Glisson's capsule.


Primary lipoma of the spleen. Report of a case.


Mental health services in Pinal County.

Mental health services in Pinal County.


The elusive profile of the teenage drug user.


The horizons of pediatrics.

The horizons of pediatrics.


Program of community medicine at the University of Arizona College of Medicine.


Placental transmission of anaesthetic agents.


The influence of neuroleptanalgesic drugs on cerebrospinal fluid pressure.


The effects of anaesthesia with thiopentone, nitrous oxide, narcotics and neuromuscular blocking drugs on renal function in normal man.


A comparison of Macrodex and stored blood as replacement for blood loss during planned surgery. II. Changes in peripheral haematocrit and whole body-large vessel haematocrit ratio.


Changes in the bicarbonate concentration of lumbar and cisternal cerebrospinal fluid in man following acute hypocapnia and hypercapnia.


Laboratory studies of inhalation anaesthetics.


Pulmonary mechanics during anaesthesia. IV. Effect of intravenous isoprenaline in asthmatic patients.


A study of the cardiovascular effects of chlormethiazole.


Blood loss during Caesarean section under general anaesthesia.


Electroconvulsive therapy no-relaxant anaesthesia.


Essential progressive iris atrophy.

Essential progressive iris atrophy.


Problem of aortic vascular rings and other anomalies of the aortic arch.


Diabetic retinopathy in Nigerians. A study of 758 patients.


Trial results of a hand-held applanation apparatus.


Postoperative iris foreign bodies.

Postoperative iris foreign bodies.


Outbreak of superficial keratitis in rubber workers.


Ocular damage caused by Paraquat.

Ocular damage caused by Paraquat.


Tarsus as buckling material in retinal detachment surgery.


Surgical restoration of flat anterior chamber. Air injection and posterior sclerotomy through the same incision.


Quantitative measurement of abnormal retinal correspondence.


Osmotic treatment of hyphaema.

Osmotic treatment of hyphaema.


Occlusion of the retinal artery in two cases of orbital granuloma.


Transilluminator using fibre ray lighting.


Ex-addict hostel at Lewisham.

Ex-addict hostel at Lewisham.


Primary subacute haematogenous osteomyelitis.


Choriocarcinoma after hydatidiform mole. Studies related to effectiveness of follow-up practice after hydatidiform mole. Chemotherapy, in conjunction with other methods of treatment, was used in 100 patients with invasive hydatidiform mole or choriocarcinoma following mole. When treatment was instituted within two to six months of the antecedent mole serious drug resistance was not encountered, drug toxicity was slight, the duration of treatment was comparatively short, and sustained remissions were obtained in 57 out of 60 patients. When the start of chemotherapy was delayed beyond six months drug resistance occurred in many instances, toxicity was often severe, the duration of treatment was much longer, and sustained remissions were obtained in 22 out of 40 patients.The practice of giving prophylactic chemotherapy to all patients with mole is not established as effective or safe. Differences in the social background to hydatidiform mole in different geographical areas may be such that conclusions based on evidence from one area are not necessarily applicable to another.Careful follow-up after mole remains essential, though present methods often fail to ensure recognition of choriocarcinoma while it is still curable. Standard qualitative and quantitative methods for detecting the continued excretion of chorionic gonadotrophin, though useful, are sometimes too insensitive. It is suggested that to supplement local arrangements some form of centralized or regionalized follow-up service based on notification of patients with hydatidiform mole, and making use of radioimmunoassays for chorionic gonadotrophin, could reduce deaths attributable to late diagnosis.


Massive subaponeurotic haemorrhage in infants born by vacuum extraction. Nine out of 232 infants on whom the vacuum extractor was employed developed subaponeurotic haemorrhage and two of these infants died. In a further 78 infants born by vacuum extraction, all of whom received intramuscular vitamin K(1), four sustained subaponeurotic haemorrhage and one died. This type of haemorrhage was not encountered in over 12,000 infants born by other methods. Its relationship to vacuum extraction was found to be significantly more frequent when the thrombotest level was 10% or below of normal adult activity. It is suggested that infants born by vacuum extraction and with a thrombotest level of 10% or below might be protected from subaponeurotic haemorrhage by the transfusion of fresh frozen plasma.


Comparison of birth weight-gestation distribution in cases of stillbirth and neonatal death according to lesions found at necropsy. The birth weight/gestation distribution of a large series of cases of perinatal death has been analysed according to the lesion (or lesions) present at necropsy. Among the lesions associated with low gestation babies dying with hyaline membranes have a much higher mean birth weight for gestation than either the babies with intraventricular haemorrhage or "no cause found." Among infants dying of intrapartum asphyxia or cerebral birth trauma it was found that those who were stillborn with trauma had, at term, a significantly higher mean birth weight than the control livebirths, and that, at all gestations, the stillbirths with trauma were, on average, heavier than the babies dying neonatally with this lesion. Cases of intrapartum asphyxia were smaller than the stillbirths with trauma, but those dying during the second stage of labour were larger than those dying during the first stage.Cases of intrauterine pneumonia-that is, stillbirths and first-day deaths-were also shown to be larger for length of gestation than cases of extrauterine pneumonia-that is, deaths between the second and the 28th day. The cases with haemorrhagic pneumonia, however, were, at least at term, smaller than the cases of extrauterine pneumonia, and cases of massive pulmonary haemorrhage showed evidence of growth retardation at all gestations.


Combined procedure of aspiration termination and laparoscopic sterilization. Termination of pregnancy and laparoscopic sterilization has been performed in 101 women in a one-year period. The complication rate was low and the average stay in hospital was short. With close supervision and co-operation between the gynaecologist and the patient's general practitioner it is suggested that this is a safe and economic procedure.


Virulence of temperature-sensitive mutants of influenza virus. The acquisition of temperature-mutant (ts) defects in a strain of influenza virus has been shown in mice to be associated with diminished virulence, though the antibody-producing stimulus remained. It is suggested that three advantages may make ts strains potential sources of attenuated live influenza vaccine-the ease of obtaining the strains, the ease of testing the vaccine strain, and the high yield of vaccine doses from a single egg.


Thirteen children from twelve pregnancies in sickle-cell thalassaemia.


Shock, coma, and electrocardiographic change with enzyme release in case of wasp-sting allergy.


Transient blindness.

Transient blindness.


Distribution and origins of manpower and work-load in the psychiatric services.


Filming during anaesthesia.

Filming during anaesthesia.


Depression following fluphenazine treatment.


Cancer and the nervous system.

Cancer and the nervous system.


Nail changes in gout.

Nail changes in gout.


Detection of hyperparathyroidism.

Detection of hyperparathyroidism.


Elbow disorders.

Elbow disorders.


Modern trepanation. A note of the present-day use of prehistoric therapy.


Wallerian degeneration: ultrastructural and histochemical studies.


The treatment of superficial fungous infections. Superficial fungous infections of the skin often are difficult therapeutic problems especially if the laboratory identification of the organism, necessary to guide selection of means of treatment, is not obtained. Proper diagnosis will reveal that some infections need certain specific antifungal drugs topically applied, another group will yield to other less specific topical therapy, and a third type can be successfully influenced only by oral administration of griseofulvin.


New concepts in cancer control. Preventable and avoidable cancers.


The catheter. How to use and when not to use. Catheterization should not be used without true indication. Careful control of hydration, sedation, anesthesia and use of anticholinergic agents before, during and after operation can do a great deal to prevent the need for catheterization. When the procedure is necessary, simple, inexpensive measures of care usually are sufficient. Prophylactic antisepsis before and after, with reexamination of the urine after discontinuance of antiseptic drugs to make sure there is no recrudescence, prevents acute and chronic infections. The catheter recommended for routine male and female catheterization is the 14-16 (French) olive tip coude (Tieman) catheter or the Tieman-Foley. Closed drainage systems are the best. Continuous irrigation is without value. Water is an excellent irrigant. Calcium deposits are prevented by Renacidin(R) instillation and acetic acid irrigation.


Neurosurgical aspects of unexplained unconsciousness. Neurosurgical experiences and diagnostic difficulties with unconscious patients without diagnosis included cases of intracranial neplasia, cerebral arteriosclerosis, subdural hematoma, traumatic subcortical hemorrhage, subdural abscess, rheumatic encephalitis, spontaneous subarachnoid hemorrhage, subacute bacterial endocarditis and emboli, myocardial infarction and emboli, spontaneous subcortical hemorrhage, fat embolism, meningitis, drug intoxication, uremia, cases in which the cause of death was not clearly established, and phycomycosis of the central nervous system.


Larval conjunctivitis in California caused by Oestrus ovis.


University of California, Los Angeles, school of Public Health.


Pharmacogenetics.

Pharmacogenetics.


Congenital histiocytosis X.

Congenital histiocytosis X.


The clinical importance of pharmacogenetics. These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California Medical Center, San Francisco. Taken from transcriptions, they are prepared by Drs. Martin J. Cline and Hibbard E. Williams, Associate Professors of Medicine, under the direction of Dr. Lloyd H. Smith, Jr., Professor of Medicine and Chairman of the Department of Medicine.


Cardiovascular roentgenology: conventional studies.


New concepts in cancer control. Preventable and avoidable cancer.


Therapeutic abortion and mental health.

Therapeutic abortion and mental health.


Current status of tuberculin testing.

Current status of tuberculin testing.


Metastatic malignant melanoma of ciliary body and choroid from a primary melanoma of skin.


Primary ovarian pregnancy.

Primary ovarian pregnancy.


Psychiatric emergencies in general practice.


The use of trypsin in the treatment of inflammatory oedema.


The interpretation of the rise of population in England and Wales.


The rarity of hypertensive retinopathy in the African.


A bilharzioma of the abdomen.

A bilharzioma of the abdomen.


Distribution of radioactivity after administration of taurine-35S in rats.


Pressure-flow relationships in the coronary circulation.


Chronotropic effect of cardiac glycosides in cats, dogs, and rabbits.


Engineering simulation of the viscous behavior of whole blood using suspensions of flexible particles.


Autoregulation of the total systemic circulation following destruction of the central nervous system in the dog.


Inhibition of incorporation of leucine into myocardial proteins of the rat by antiarrhythmic agents.


Release of adenosine by the normal myocardium in dogs and its relationship to the regulation of coronary resistance.


Answers to a congressman's questions.

Answers to a congressman's questions.


Influence of the direction of the atrial wave front on A-V nodal transmission in isolated hearts of rabbits.


Analgesia and anesthesia in cesarean hysterectomy.


Indications and techniques for cesarean hysterectomy.


Tubal ligation versus cesarean hysterectomy.


Cesarean hysterectomy at the Charity Hospital in New Orleans--1000 consecutive operations.


Cesarean hysterectomy at the Boston Hospital for Women.


Pitfalls and complications of cesarean section hysterectomy.


Dysmenorrhea.

Dysmenorrhea.


Psychosomatic aspects of menstrual disorders.


LSD ingestion. A review with four case reports.


Industry and mental illness.

Industry and mental illness.


Primary pulmonary actinomycosis. A case report.


Comparative studies on the activity of 3-beta-hydroxy-delta-5-norcholenic acid on the delta-24-sterol reductase enzyme(s) in an insect and the rat.


Hirsutism: a disorder frequently associated with menstrual abnormalities.


Climatology and medicine. VI.

Climatology and medicine. VI.


Screening for cancer: how should it be done?


Continuing medical education.

Continuing medical education.


A science of learning for medical science.


Are herbicides contaminating surface and ground water in Delaware?


Structure and function: why did the heart stop?


Physicians and the smoking controversy.

Physicians and the smoking controversy.


Pathology of heart valve replacement surgery: autopsies of 62 patients with Starr-Edwards prostheses.


The mechanical suture with UKL-40 and UKL-60 in pulmonary surgery.


Pulmonary cryptococcosis: report on the treatment of nine cases.


Bronchial asthma and asthmatic bronchitis determined by simple chemicals.


Postexercise electrocardiogram in screening for latent ischemic heart disease. A study with clinical follow-up observation.


Control of massive hemorrhage during bronchoscopy.


Post-infarction conduction disturbances: a self-teaching program.


The Mono-Vacc tuberculin skin test.

The Mono-Vacc tuberculin skin test.


Long-term follow-up (one to four years) of heart valve prtheses (102 consecutive patients).


Breast carcinoma as a cause of dysphagia.


Primary leiomyosarcoma of the lung.

Primary leiomyosarcoma of the lung.


Pericardio peritoneal communication--an additional etiologic factor in purulent pericarditis.


Para-aortic mass in an asymptomatic man.


A useful roentgen sign in dissecting aneurysm of the thoracic aorta.


Ventricular preexicitation simulating anteroseptal infarction.


Lipids of the mutant bronze mosquito, Aedes aegypti (L.).


Storage and retrieval of information from insect specimens.


Five years ago--and five years from now.


Economics and the purchasing manager. 1.


What are hospital architects planning?

What are hospital architects planning?


Changing patterns in public health nursing and medical social work.


Group survival and change.

Group survival and change.


The practicing physicians's role in hospital management--a consultant's view.


The practicing physician's role in hospital management--a consultant's view.


The practicing physician's role in hospital management--an administrator's view.


Comprehensive health planning: problems and benefits.


Reorganizing a hospital's corporate and board structure.


Pharmacist vital to utilization review.

Pharmacist vital to utilization review.


Whither leukaemia?

Whither leukaemia?


Histochemical and submicroscopic studies on sialic acid in induced epidermal cancer in relation to cell detachment and metastasis.


Radiation and radiomimetic agents. I. The distribution of P32 labelled cyclophosphamide in albino rats and in humans.


Carcinoma cervix uteri (a clinico-pathological study of 640 cases).


Major salivary gland tumours.

Major salivary gland tumours.


Collision tumour of the uterus.

Collision tumour of the uterus.


A case of Burkitt's lymphoma. Clinical features and response to therapy.


Benign chondroblastoma of talus. A case report.


Malignant sacrococcygeal teratoma. A case report.


Immunological studies on mouse mammary tumors. II. Characterization of tumor-specific antibodies against mouse mammary tumors.


Immunological studies on mouse mammary tumors. 3. Surface antigens reacting with tumor-specific antibodies in immune adherence.


Immunological studies on mouse mammary tumors. IV. Extraction and solubilization of transplantation antigen of mouse mammary tumor.


The occurrence of tumours in F1, F2, and F3 descendants of pregnant mice injected with 7,12-dimethylbenz(a)anthracene.


Gastric cancer in man and physical activity at work.


Pulmonary resection as treatment for coccidioidomycosis of the lung. Review of 40 cases.


Massive resection of the small intestine. Survival of two patients with less than two feet (60 cm) of small bowel.


Aid of LN2-cryospray in extirpation of brain tumors.


Postoperative treatment of carcinoma of the breast with telecesium.


Enterocele. The enigma of the posterior vaginal hernia.


Lingual thyroid.

Lingual thyroid.


Cancer and thrombohemorrhagic disease.

Cancer and thrombohemorrhagic disease.


Bilateral ankylosis of the elbows in extension due to contracture of the triceps. A case report.


Carcinoma of the colon.

Carcinoma of the colon.


Elderly primipara. An analysis of 1574 cases.


The postinjection cord syndrome of varicose veins and its significance for therapy.


Observations on thermal burns treated with liquid nitrogen.


Complications with cataract cryoextraction following zonulolysis.


Arterial reconstruction with vein grafts.


Whole body counting for appraisal of radiation risk in thorium dioxide delineation of brain abscess cavity.


Acute appendicitis in patients over the age of sixty.


Total excision of the biceps muscle. An unusual case of a malignant tumor.


Acrocephalosyndactyly (Apert's syndrome).


The "lighthouse" and other metaphors in gynecology.


Transient traumatic cerebellar dysfunction. Report of a syndrome.


Treatment of uterine prolapse by vaginal hysterectomy.


Surgical treatment of wrinkles of the lower eyelids associated with herniation of orbital fat. Muscular-cutaneous flap technique.


Surgical management of perforated thyphoid ulcer.


Intraabdominal extraperitonealization of the colon anastomosis.


Management of cervical incompetence.

Management of cervical incompetence.


Environmental appraisal--particulate matter, oxides of sulfur, and sulfuric acid. Discussion.


Toxicologic appraisal of particulate matter, oxides of sulfur, and sulfuric acid. Discussion.


An epidemiological appraisal of the effects of ambient air on health: particulates and oxides of sulfur. Disscussion.


Environmental appraisal: Oxidants, hydrocarbons, and oxides of nitrogen. Discussion.


Air quality criteria--toxicological appraisal for oxidants, nitrogen oxides, and hydrocarbons. Discussion.


An appraisal of epidemiologic data concerning the effect of oxidants, nitrogen dioxide and hydrocarbons upon human populations. Discussions.


An appraisal of epidemiologic data concerning the effect of oxidants, nitrogen dioxide and hydrocarbons upon human populations.


Carbon monoxide and lead--an environmental appraisal. Discussion.


Epidemiological bases for possible air quality criteria for lead. Discussion.


Toxicological appraisal of lead in relation to the considerable concentration in the ambient air. Discussion.


Toxicological appraisal of carbon monoxide. Discussion.


Model reporting area for blindness.

Model reporting area for blindness.


Toxicologic and epidemiologic bases for air quality criteria. Carbon monoxide and lead. Session summary.


Learning efficiency in low vision.

Learning efficiency in low vision.


A simplified procedure for prescribing low vision reading lenses.


Non-optical low vision services.

Non-optical low vision services.


Management of the low vision patient with peripheral field loss.


Nystagmus and low vision.

Nystagmus and low vision.


Psychological factors in working with partially sighted persons.


The controlled-pupil contact lens in low vision problems.


What constitutes blindness? I. Optics.

What constitutes blindness? I. Optics.


The simplified approach to low vision.

The simplified approach to low vision.


Illumination for partially seeing school children.


A cornerstone of professional strenght.

A cornerstone of professional strenght.


The making of public opinion.

The making of public opinion.


Communications please.

Communications please.


A public relations path.

A public relations path.


Pitfalls and platitudes of optometric public relations.


You feel great--when you communicate.

You feel great--when you communicate.


An award is an award, is an award ... or is it?


Publish and/or perish ... an admonition.


The feminine touch.

The feminine touch.


Taking a brief rear-view mirror glance.

Taking a brief rear-view mirror glance.


Plasma creatine phosphokinase changes induced by freezing injury and adaptation to cold.


Gas chromatographic analysis of amines in volatile substances of Streptococcus lactis.


Identification and determination of organomercurial fungicide residues by thin-layer and gas chromatography.


Chromatographic properties of some cyclic alpha-imino acids homologous to proline, and their DNP-, DNS- and PTH-derivatives.


Thin-layer chromatography of malto-oligosaccharides.


Ion-exchange chromatography of tissue nucleotides.


Gas-liquid chromatographic determination of benzene metabolites.


Interference of ethoxyquin in the thin-layer chromatographic estimation of aflatoxin.


A sensitive method of documentation of porphyrin and hemin thin-layer chromatograms.


The detection of sulphonamido groups.

The detection of sulphonamido groups.


The separation of isoasparagine from asparagine.


Influence of gastrointestinal loads on meal-eating patterns.


Invariance of the rat's rate of drinking.


Monocular and binocular control of horizontal optokinetic nystagmus in cats and rabbits.


Adaptive food sampling patterns in vitamin deficient rats.


Patterns of autonomic and somatic activity during classical conditioning of a motor response.


Anterior limbic cortex and partial reinforcement effects on acquisition and extinction of a runway response in rats.


Visually mediated behaviors following neocortical destruction in the rat.


Effects of stimulation of midbrain tegmentum on performance of a brightness discrimination in the rat.


Stimulus control value of spreading depression demonstrated without shifting depressed hemispheres.


Effects of d-amphetamine and frontal ablations on response suppression in rats.


Inhibition of flexion reflex by rewarding or aversive central stimulation.


Sodium amobarbital and effects of frustrative nonreward.


Effects of pretrial and posttrial administration of cholinergic and anticholinergic drugs on spontaneous alternation.


Thermoregulatory adjustments in rats after removal of the frontal poles of the brain.


Behavioral changes following disruption of central cholinergic pathways.


The clearance of renin from the peripheral plasma of the marsupial Trichosurus vulpecula.


An interesting anatomical relationship between the hamster pineal gland and the ventricular system of the brain.


Growth hormone concentration in human pituitary tumours.


Transplacental influence of oestrogen upon ovulatory mechanisms in the rat.


Hypogonadotrophic hypogonadism in adult male rats treated with gonadotrophin in neonatal life.


Uroterpenol, a Pettenkofer chromogen of dietary origin and a common constituent of human urine.


Hormone secretion during early pregnancy in the mouse.


Progesterone metabolism in the ewe.

Progesterone metabolism in the ewe.


Increased production of follicle-stimulating hormone in immature female rats by a single injection of androgen or oestrogen.


Endocrine control of the metabolism of oestradiol by rat liver microsomes.


The release of antidiuretic hormone from the pituitary stalk after intravenous calcium chloride or magnesium chloride infusion in rats.


The calcitonin secreting C cells and their relationship to the APUD cell series.