Systemic lupus erythematosus.

Systemic lupus erythematosus. Systemic lupus erythematosus is a polysystemic disease with a high incidence of associated glomerulonephritis. Patients with sle rarely have the destructive arthritis so characteristic of rheumatoid arthritis. An unusual case is presented in which both glomerulonephritis and destructive arthritis occurred simultaneously, justifying the diagnosis of both systemic lupus erythematosus and rheumatoid arthritis.Immunohistochemical studies in lupus glomerulonephritis suggest that the pathogenetic mechanisms involve the deposition of immune complexes containing "nuclear" antigens and antinuclear antibodies in the lesions. The detection of mixed cryoglobulins in the sera of patients with sle suggests that a portion of the circulating immune complexes may precipitate at reduced temperatures and be detected as mixed cryoglobulins. The therapy of lupus glomerulonephritis with combinations of corticosteroids and azathioprine, though still in an investigative state, holds great promise. Similar abnormalities in diseases of minks and mice and in sle suggest similar pathogenetic mechanisms in the three species involved. Since the diseases in the lower animals have been associated with persistent viral infection, the investigation of the role of persistent infection in sle seems warranted.


Polymyalgia rheumatica and associated arteritis: A review.


Systemic lupus erythematosus.

Systemic lupus erythematosus.


Whither nursing?

Whither nursing?


Polymyalgia rheumatica.

Polymyalgia rheumatica.


A medical corpsmen project.

A medical corpsmen project.


Prosthetic replacement of the mitral valve: an assessment of the clinical and hemodynamic results of operation.


Abortion in California. State Supreme Court decision under former law sheds some light on conduct under amended act.


Public health report. The challenge ahead.


Survey on medical student attitudes. A socio-economic report of the Bureau of Research and Planning, California Medical Association. One of the concerns of the Committee on the Role of Medicine in Society of the California Medical Association is the apparent "attitude gap" between medical students and physicians already established in practice. In November 1967, the first of a series of meetings took place between Committee members and senior students from each California medical school. Discussion ranged from curriculum planning to individual and organizational politics, and revealed differences of opinion between students and physicians on such issues as Medicare and the financing of health care for the nation. These discussions suggested to members of the Committee that several clearly defined subject areas were worthy of further investigation. It was decided, therefore, that a questionnaire be sent to medical students and residents, with the goal of gaining a better understanding of the nature and extent of such differences of opinion. Some of the highlights of the findings of this survey are discussed in this Socio-Economic Report.


Renal blood flow in patients with hypertension.


Variation in the availability of transferrin-bound iron for uptake by immature red cells.


The relationship between gas exchange and changes in blood lactate concentrations during exercise.


The immediate buffering of retained carbon dioxide in man.


Potassium retention during the respiratory alkalosis of mild hypoxia in man: its relationship to aldosterone secretion and other metabolic changes.


The effect of expiratory flow rate on regional lung emptying.


Change in pulmonary ventilation in different postures.


Control of aldosterone secretion during acclimatization to hypoxia in man.


Blood pressure survey in pregnancy.

Blood pressure survey in pregnancy.


The extravascular retention of albumin in wound tissue and its contribution to the postoperative hypoalbuminaemia in rabbits.


The metabolism of cholesterol in two hypercholesterolaemic patients treated with cholestyramine.


Carbohydrate metabolism by rat liver slices incubated in serum obtained from uraemic patients.


The effect of malnutrition and food habits on the concentrating power of the kidney.


Forearm metabolism in patients with chronic liver disease.


Elevated pulmonary artery wedge pressure at rest and during exercise in chronic bronchitis: fact or fancy.


Iron absorption in idiopathic haemochromatosis and its measurement using a whole-body counter.


The mechanism of decreased specific airway conductance in man during hypercapnia caused by inhalation of 7 per cent CO2.


In vivo dialysis of faeces as a method of stool analysis. IV. The organic anion component.


The action of pyridoxine in primary hyperoxaluria.


Induction of drug metabolizing enzymes in man and rat by dichloralphenazone.


Uptake of amino acids by rat liver.

Uptake of amino acids by rat liver.


The interaction between LATS and thyroid tissue in vitro.


Effect of thyroid hormones on sodium transport by rat colon.


Aspects of controlled haemodialysis.

Aspects of controlled haemodialysis.


Changes of chest configuration during breathing in children with reversible airways obstruction.


Oscillations in expiratory gas flow during a forced vital capacity manoeuvre.


The location of the chemoreceptor controlling gastric acid secretion during hypoglycaemia.


Nocturia due to reversal of circadian rhythm in paitents on long-term steroid therapy.


Respiratory and acid-base changes during the crises in relapsing fever.


Subcellular localization of radioactive vitamin B12 during absorption by guinea-pig ileum.


Absorption of amino acids and the dipeptide, carnosine, from the gut in normal subjects and a case of Hartnup disease.


The validation of insulin standards by comparison with endogenous hormone at different antiserum concentrations.


Glucose metabolism by adipose tissue in adult diabetes.


Interaction of neomycin with micellar fatty acid and cholesterol.


The incidence of thyroid and gastric autoimmunity in patients with diabetes mellitus.


Radioimmunoassay techniques.

Radioimmunoassay techniques.


Saturation analysis.

Saturation analysis.


Immunoradiometric assay of polypeptide hormones.


Reproductibility of estimates: use of standards and reference reagents.


The isolation and assay of human parathyroid hormone.


Application of the radioimmunoassay technique for determining plasma levels of oxytocinase.


A direct finite element analysis method for particle mechanics: the three-body problem.


Electrostatic theory of ion movements through biological cell membranes.


The application of the radioimmunoassay techniques for determining serum levels of digoxin.


Study of a biological model of membrane function by finite element analysis.


Simulation method for the design and data correction of calorimeters.


A general method for calculating the dynamics of linear mathematical models of biological systems.


A mathematical model of biological growth and regression.


Pictorial pattern recognition.

Pictorial pattern recognition.


"Direct analysis" or "finite element analysis" in biology: a new computer approach.


Considerations in designing a system for developing dental caries models.


Finite element methods in cell dynamics fundamentals.


Changes in titer of the brain hormone during development of the silkworm. Bombyx mori.


Phytochrome action in Oryza sativa L. 3. The separation of photoperceptive site and growing zone in coleoptiles, and auxin transport as effector system.


Effect of light on auxin transport and elongation of Avena mesocotyl.


Endocrinological studies on spermatogenesis in the silkworm, Bombyx mori L.


Treatment of parkinsonism with L-dopa (study of 105 patients).


Drug efficacy and diagnostic specificity in manic depressive illness and schizophrenia.


Panel on the humanistic approach to sexuality. Sex and character formation.


Sex and love.

Sex and love.


Adolescence and human sexuality.

Adolescence and human sexuality.


Humanizing and dehumanizing aspects of human sexuality.


Freedom and sexuality.

Freedom and sexuality.


Effect of antiserum to mouse testes extract on the fertility of female mice.


Effect of glycogen with adrenaline on experimental atherosclerosis.


Role of catecholamines in experimental atherosclerosis.


Pharmacological investigations of usaramine, an alkaloid isolated from Crotalaria brevifolia.


A comparative study of wound healing.

A comparative study of wound healing.


Lipids of Culex pipiens fatigans during metamorphosis.


Effect of gamma-radiation on callus growth of Phylloxera gall & normal grape stem tissues in culture.


Prevention of busulphan induced antispermatogenesis in rats by follicle stimulating hormone & zinc.


Effect of buffer salt & H-ion concentration on potato virus X infection on Capsicum pendulum Willd.


Effect of estrogen on survival of spermatozoa in the genital tract of castrated male rats.


Effects of endoxan & 5-fluorouracil on the primary culture of melanoma cells.


Effect of oxotremorine on acetylcholine content of brain & peripheral tissues in rats.


Behaviour of black chromatophores in the crab, Paratelphusa hydrodromous Herbst.


Effect of carotenoid pigments on sublethal radiation injury in rats.


Salmonella typhi "O" agglutinin titres in human sera with differently prepared suspensions in the conventional Widal test.


Effect of starvation on the trophocyte nucleus of Musca domestica.


Hyaluronate lyase activity of staphylococci.


Beta-glucuronidase of crystalline style of lamellidens marginalis.


Interference with pituitary luteinizing hormone activity by intrauterine devices in goats.


Role of bovine growth hormone in chemically induced skin carcinogenesis in Swiss albino mice.


Effect of altered hormonal states on histochemical distribution of alkaline & acid phosphatase activity in the rat prostatic complex.


Protein synthesis in the testis of protein-deficient rats. Effect of gonadotrophic hormone & testosterone propionate.


Fate of cobalt-60 I-nitroso 2-naphthol chelate in albino rats after intravenous administration.


Succinate dehydrogenase activity & protein charges in cell-free system.


Effect of oxotremorine on histamine content of blood & peripheral tissues in rats.


Effects of psychotropic drugs on acetylcholinesterase activity of mouse brain.


Role of reticulo-endothelial system in the mechanism of cobalt chloride induced blood cholesterol rise.


Cation content in th phasic & tonic muscles of frogs & its seasonal variation.


Effect of alcohols on smooth & skeletal muscles.


Respiratory metabolism in virus-infected Capsicum annuum L. & Cucurbita pepo L.


Transplacental transmission of polio antibodies, neutralizing & flocculating in rabbits. Decay of antibody level in litters following birth & immunogenic potency of neonate rabbits.


Relationship of blood group antigens in cattle to homologous spermatozoan antigens as detected by natural agglutinins.


Screening of Indian plants for biological activity. II.


Influence of vitamin B 12 on fecal excretion of cholesterol and bile acid of albino rats kept on high cholesterol diet.


Alpha-amylase of the hepatopancreas of the scorpion, Heterometrus scaber.


Decarboxylase reactions of vibrios.

Decarboxylase reactions of vibrios.


Biological activity of the amphioxus endostyle.


Nature of intestinal motility.

Nature of intestinal motility.


Seasonal variations in summer cells of adrenal of male frogs (Rana trigrina).


Chick morphogenesis in 2-amino-4-methylpyrimidine.


Nutritive value of leaf protein from lucerne (Medicago sativa). Growth responses in rats at different protein levels & to supplementation with lysine &-or methionine.


Erythromycin fermentation by Streptomyces erythreus.


Studies on vaccination with lentogenic strains of Newcastle Disease virus administered through spray and drinking water.


Studies on female reproduction in Murrah buffaloes.


Investigations on gestation period in Gir cows.


Epithelial metaplasia in experimental vitamin A deficient goats.


Differences in pattern of oxygen consumption by newborn sheep of two breeds.


Correlation of birth weights and weights at one and six months of age of cross-bred calves.


Effects of feeding ruminants non-protein nitrogen as the only nitrogen source.


General practitioners and family planning in Sheffield.


Family growth in Aberdeen.

Family growth in Aberdeen.


Recent trends and patterns in fertility in Australia.


Effect of fewer births on average income. Using the parameters of developing countries, a model of the effects of varying degrees of birth control is analysed.  With the use of no, increasing, and full birth control, the per capita income rises from 150 dollars initially to 117 dollars, 202 dollars, and 216 dollars after 15 years; and to 206 dollars, 255 dollars, 268 dollars after 25 years.  The value of preventing one birth is 288 dollars over 10 years, and 705 dollars over 25 years; but the cost is only 10 dollars per birth averted.  With no birth control the rate of product innovation would need to be 1.5 times the present rate, and saving propensities would need to be doubled to tripled.  If countries could have full birth control participation including half of all fertile couples, at 2.00 dollars per couple, the cost to the government would be less than 3% of all expenditures for economic development.  As shown in the model, the advantages of such a policy are beneficial to the economic situation in the country.


Delineation of the lowest social class.

Delineation of the lowest social class.


Intervals between births in families containing one set of twins.


Attempted suicide and the experience of violence.


The sociobiological aspects of the national survey on fecundity and fertility in Belgium.


Multiple births in Australia, 1944-63.

Multiple births in Australia, 1944-63.


Optical noise in photometric scanning of thin media chromatograms. I. General theory and its application to single-beam transmission measurements.


Optical noise in photometric scanning of thin media chromatograms. II. Double-beam difference systems.


The gas chromatography of aromatic acids as their trimethylsilyl derivatives, including applications to urine analysis.


Tobacco chemistry. II. Analysis of the gas phase of tobacco smoke by gas chromatography-mass spectrometry.


Determination of creatinine in soups and soup preparations by ion-exchange chromatography.


Separation and detection of gallic acid and its alkyl esters by polyamide thin-layer chromatography.


Chromatography of aromatic hydrocarbons on impregnated layers.


Thin-layer chromatography of nucleic acid bases, nucleosides, nucleotides and related compounds. IX. Quantitative analysis in situ reflectance spectroscopy.


An inexpensive and efficient pyrolysis unit for the analysis of picloram and other herbicides by thermal decomposition.


Thin-layer chromatographic investigations of some synthetic compounds having laxative properties.


Micellar size, shape, and hydration of nonionic surfactants.


A technique for improved thin-layer chromatography of phospholipids.


Neonatal castration, androstenedione, and the mating behavior of the male rat.


Lack of effect of drinking of stimulation of the ventral amygdala of rat with GABA.


Differential enrichment potential of visual experience with angles versus curves.


Complexity, amounts of contour, and visually dependent behavior in hooded rats, domestic chicks, and human infants.


Overpopulation effects on social reduction of emotionality in the albino rat.


The course of Pavlovian excitation and inhibition of fear in rats.


Role of contextual discrimination in fear conditioning.


Free versus forced exposure with two procedures for conditioning and measuring fear in the rat.


Effects of differential and nondifferential reinforcement on generalization test performance by cats.


The incentive of brain-stimulation reward.


Effects of stimulation intensity on behavior elicited by hypothalamic stimulation.


Self-stimulation: failure of pretrial stimulation to affect rats' electrode preference.


Verbal and nonverbal factors in right-hemisphere speech: relation to early neurological history.


Hippocampal lesions and the cardiac component of the orienting response in the rat.


Effects of CS preexposures on avoidance learning in rats with hippocampal lesions.


Role of the caudate nucleus in spatial orientation of rats.


Schizophrenia as a "put-on".

Schizophrenia as a "put-on".


Schizomimetic conditions and schizophrenia.


An experimental procedure for the modification of psychotic behavior.


Frequency of dream recall estimated by three methods and related to defense preference and anxiety.


Operant-interpersonal treatment for marital discord.


Intelligence defined as effectiveness of approaches.


Personal adjustment as a determinant of aggressive behavior toward the mentally ill.


Effect of information, subject age, and instructional set on predictive judgments.


Rorschach prediction of success in clinical training: a second look.


Verbal and overt-behavioral assessment of a specific fear.


Relations between personality and smoking behavior in preadult subjects.


Effects of cues and examiner influence on two Wechsler subtests.


Relationship of work therapy to psychiatric length of stay and readmission.


Some personality and aptitudinal correlates of the "A-B" therapist scale.


Distinctive personality attributes of child-abusing mothers.


Prospective span as a cognitive ability.


Should WISC subjects explain picture arrangement stories?


Dioxane and dioxaspiro derivatives as attractants for male yellow-fever mosquitoes.


Use of the multiple regression equation in the prediction of the insecticidal activity of anticholinesterase insecticides.


The residual fate of N,N,N',N'-tetramethyl-p-piperidinophosphonic diamide after injection, tarsal contact, and topical application to the boll weevil.


Toxicology and physiology of DDT resistance in the German cockroach.


Absorption of DDT and metabolism of DDT and related compounds by DDT-resistant codling moths.


The chemosterilant effect of anthramycin methyl ether in Drosophila melanogaster.


The metabolism of Bayer 9017 in calves.

The metabolism of Bayer 9017 in calves.


Further evaluation of animal systemic insecticides, 1968.


Toxicity of ouabain (G-strophanthin) to adult house flies.


Ectopic pregnancy: a review of 201 cases at Southern Baptist Hospital.


Clinical evaluation of a plastic ring intra-uterine contraceptive device (INCON).


Senility.

Senility.


Demonstration of bladder tumors by endo- and perivesical gas insufflation and arteriography.


The search for safe air.

The search for safe air.


Menstrual abnormalities following the use of oral contraceptives.


Some issues in health insurance.

Some issues in health insurance.


Blood pressure, height and weight status of a group of Lebanese.


Pitfalls in the diagnosis of amoebic liver abscess (2 case reports).


Triceps tendon rupture (repair of an old rupture).


Familial hypercholesterolemia.

Familial hypercholesterolemia.


Recognition and treatment of chronic liver disease in the disadvantaged.


Equal opportunity--a reality for minority students in the health professions?


Oral contraceptives and urokinase activity.


The distribution of black physicians in the United States, 1967.


The National Medical Association: Jordan B. Noble revisited.


Hyphema--special problems.

Hyphema--special problems.


A urologic view of primary hyperparathyroidism.


Radiotherapy of the ear.

Radiotherapy of the ear.


Hair transplantation: interesting sidelights.


Pitfalls in diagnosis and treatment of the acutely injured hand.


Congenital absence of the vagina.

Congenital absence of the vagina.


Lung diffusing capacity response to exercise in sarcoidosis. A physiologic study.


Nose and chinplasty.

Nose and chinplasty.


The brittle diabetic.

The brittle diabetic.


Man on earth deserves equal time with man on the moon.


Medicine and education at the Danang Medical Center.


Longitudinal myelotomy for spasticity.

Longitudinal myelotomy for spasticity.


Effects of percutaneous cervical cordotomy on pulmonary function.


Clinical application of hyperbaric oxygenation in the treatment of acute cerebral damage.


Pre- and postoperative evaluation of cerebral blood flow in low-pressure hydrocephalus.


Acrylic investment of intracranial aneurysms. A report of 12 years' experience.


Experimental performance of steel and platinum electrodes with chronic monophasic stimulation of the brain.


Intrasellar germinomas: a form of ectopic pinealoma.


Intradural herniated lumbar disc.

Intradural herniated lumbar disc.


Stab wounds of the cauda equina. Case report.


Monstrocellular sarcoma of the brain: 6-year postoperative survival. Case report.


Successful removal of a large intrapontine hematoma. Case report.


Cardiac arrest after medication through central-venous catheter. Case report.


Adrenocortical nodular hyperplasia: the ageing adrenal.


Changes in the wall of the pulmonary artery after banding.


Primary dissecting aneurysms of coronary arteries.


Ultrastructural observations in Parkinsonism.


Microscopy of the pulmonary alveolar lining layer in rabbits and perinatal infants.


Solid malignant ovarian teratoma with "embryoid bodies" and trophoblastic differentiation.


The effect of Lantana camara on the liver of sheep.


Objective quantitative estimation of the acute inflammatory response.


Good samaritanism: an underground phenomenon?


A behavioral analysis of teacher expectancy effect.


Relationship between authoritarianism and attitude change as a function of source credibility and type of communication.


Commitment and expeience as determinants of assimilation and contrast.


Social power and communication within families of disturbed and nondisturbed preadolescents.


Recognition for faces of own and other race.


Behavioral correlates of peceived leadership.


Individual-group problem solving, subject preference, and problem type.


Relative toxicities and dispersing-evaluations of eleven oil-dispersing products.


Experimental fractures of the adult humerus.


An analogue computer for thermal dilution flow measurement.


Electronic techniques for radiological image processing.


Analogue computer model of the human cardiovascular control system.


A radiation power calorimeter and a radiation force meter for small ultrasonic beams.


Conversion of a typewritten or printed text into speech--a new method of typewriting and reading for the blind.


Versatile technique for the analysis of dynamic multidimensional information.


Use of a digital computer to produce a psychological test--Rabbitt's test of selective attention.


A design of an artificial control system of the cardiac output.


Construction of a fine wire thermocouple capable of repeated insertions into and accurate positioning within a controlled environmental chamber.


A new pulsatile blood flowmeter.

A new pulsatile blood flowmeter.


Biomedical engineering in India.

Biomedical engineering in India.


Percutaneous pin fixation of transcondylar fractures of the humerus in children.


Hospital operating room and the law.

Hospital operating room and the law.


Hallucinogenic drug reactions.

Hallucinogenic drug reactions.


Informed consent and expressed warranty.


The arthritides; special note on trauma. Medicolegal decisions.


Psychotherapist prescribes a drug in his office; medicolegal risks.


Injuries to the male genitalia. Anatomy of the male genitalia.


Slimming at the institute of cancer research.


Urinary incontinence after prostatectomy.


Curbs on panic and pesticides.

Curbs on panic and pesticides.


Protein synthesis in cell-free systems from reticulocytes of thalassaemic patients.


Conformation of the free and antigen-bound IgM antibody molecules.


Rifampicin: a specific inhibitor of vaccinia virus assembly.


Multiple forms of monoamine oxidase in the developing brain.


Replication of an infectious form of tobacco mosaic virus in chicken embryos.


Malignancy of somatic cell hybrids.

Malignancy of somatic cell hybrids.


Rapid changes of nuclease activities in spleens of leukaemia virus infected mice.


Effect of prostaglandin E2 on adjuvant arthritis.


Growth of differentiating testes and ovaries.


Passive transfer of adjuvant-induced arthritis and allergic encephalomyelitis in rats using thoracic duct lymphocytes.


Hyperactivity in rats bred and raised on relatively low amounts of cyclamates.


Specific genetic deletions by a carcinogenic hydrocarbon in Drosophila.


Perception and memory of the orientation of visually presented lines by children.


Changing patterns in the doctor-nurse relationship.


A new paramedical specialty. Inhalation therapy.


The need for the physician's support of the nurse in day-to-day practice.


Management of peripheral arterial diseases. I.


Drug Interactions.

Drug Interactions.


The physician's role in smoking and health.


The cavity electrocardiogram in emergency artificial pacing.


Psychiatric referrals since the Abortion Act 1967.


Exchange and simple transfusion in sickle-cell diseases in pregnancy.


Insidious rheumatic carditis and athletic activities.


Electrofocusing and protein detection and isolation.


The insulin response to glucose in patients with pancreatic disease.


Hypertrophic osteoarthropathy associated with carcinoma of the oesophagus.


Dissociative anesthesia with ketamine hydrochloride.


Some current research in oral mucous membrane diseases.


Some features of oral carcinoma. Presidential address.


Diagnosis of extrapulmonary lesions by sputum cytology.


Drug effects on canary steriotypies.

Drug effects on canary steriotypies.


Effect of chronic cold stress on catecholamine levels in rat brain.


Resistance of one-trial discriminated avoidance to chlorpromazine.


The effect of strychnine administration during development on adult maze learning in the rat.


Exploration and latent learning: differential effects of dexamphetamine on components of exploratory behaviour in rats.


The maintenance and improvement of technical standards.


The relative effectiveness of several hallucinogens in disrupting maze performance by rats.


Effects on offspring behavior of mothers' early chronic drug experience.


A new myelography jacket and harness.

A new myelography jacket and harness.


Are training objectives objectionable?

Are training objectives objectionable?


Open heart surgery in infants under deep hypothermia without cardiopulmonary bypass.


Embolectomy for chronic pulmonary embolism and hypertension.


Studies on 4-phenylpiperidine series. IX. The stereochemistry of the quaternization of some N-alkyl-4-phenyl-4-formylpiperidines.


Transformation of quinine into the indole alkaloids. I. The absolute configuration of hunterburnine alpha- and beta-methochloride.


Transformation of quinine into the indole alkaloids. II. The synthesis of 10-methoxydihydrocorynantheol and ochrosandwine.


A laboratory infection with Erysipelothrix rhusiopathiae.


The nutrition of the laying fowl.

The nutrition of the laying fowl.


The Ena antigen and antibody a genetical modification of human red cells affecting their blood grouping reactions.


Mk and Mg: some serological and physicochemical observations.


Low incidence of erythrocyte G-6-P D deficiency in aborigines of Taiwan.


Pta--a new private antigen.

Pta--a new private antigen.


Serological findings on quadrizygotic quadruplets.


New factors and alleles in the M blood-group system of the pig.


Dialogue and confrontation with Seymour Wolfbein.


Medical technology education: an impetus for revolutionary concepts.


Development of a medical technology degree program in a liberal arts college.


Laboratory management seminar.

Laboratory management seminar.


A modified chloranilic acid method for calcium determination.


Surgical treatment of peptic ulcer.

Surgical treatment of peptic ulcer.


Baroreceptor functions in the fetal lamb.


Long-term study of aerosol cyanoacrylate tissue adhesive spray: carcinogenicity and other untoward effects.


The surgical management of hepatic trauma and its complications.


Precancerous conditions of the oral mucosa. A computer-aided study.


Structure and function of hip joint innervation.


Cerebral dysfunction in children.

Cerebral dysfunction in children.


Foreign body injuries to the eye.

Foreign body injuries to the eye.


Laceration of the eyelids.

Laceration of the eyelids.


Ocular injury due to blunt trauma.

Ocular injury due to blunt trauma.


Burns to the eye.

Burns to the eye.


The care of children with intractable asthma in the Ontario Crippled Children's Centre.


Subunit structure of rabbit muscle aldolase: extent of homology of the alpha and beta subunits and age-dependent changes in their ratio.


Control of electron flow in chloroplasts by cations.


The 'SIMBOL' rating and evaluation system. A measurement tool for injured persons.


The initiation of haemoglobin synthesis in rabbit reticulocytes. 1. The incorporation of labelled valine by rabbit reticulocytes into the N-terminal position of nascent haemoglobin was investigated by deaminating the nascent peptides with nitrous acid and isolating labelled alpha-hydroxyisovaleric acid and valine after acid hydrolysis. 2. The amount of radioactivity in alpha-hydroxyisovaleric acid relative to that in valine indicated the presence of 12.3% N-terminal valine having a free amino group. This high value suggests that most if not all nascent peptides contain valine in the N-terminal position. 3. Cell-free preparations containing reticulocyte ribosomes and pH5 enzymes incorporated alpha-hydroxy-[(14)C]isovaleryl-tRNA (where tRNA refers to transfer RNA), which was obtained by deamination of [(14)C]valyl-tRNA from yeast or liver with nitrous acid, into both soluble and nascent protein. 4. When the soluble protein was chromatographed on CM-cellulose, radioactivity was found to be associated with both the alpha-and beta-globin chains. 5. The kinetics of hydrolysis of [(14)C]valine, was also investigated. Most of the material was hydrolysed rapidly at pH10, but a minor component that was relatively stable appeared to be present to the extent of about 10% of the total valyl-tRNA. Valine was, however, the only hydrolysis product detected by paper chromatography. 6. It is concluded that chain initiation in haemoglobin synthesis involves valine as the N-terminal amino acid and that the amino group of nascent protein is probably not substituted.


Compliance changes during caesarean section. A study of forty cases.


Conservative surgery for peptic ulcer.

Conservative surgery for peptic ulcer.


A trial of proxyphylline in the treatment of chronic obstructive airways disease.


Assay, purification and properties of mammalian D-2-hydroxy acid dehydrogenase. 1. A new method is described for the measurement of d-2-hydroxy acid dehydrogenase in samples of animal tissues. 2. The distribution of the enzyme in a number of animals was determined. Of the animal tissues tested, the most active source of the enzyme was found to be rabbit kidney cortex. 3. The enzyme was purified from rabbit kidney to a stage at which it appears to be homogeneous in the analytical ultracentrifuge and on polyacrylamide-gel electrophoresis. 4. The molecular weight was estimated by gel filtration to be approx. 102000; combination of gelfiltration data and the sedimentation coefficient gave a value of 95000. 5. The purified enzyme has a spectrum typical of a flavoprotein. The change induced in the spectrum on addition of d-malate or d-lactate suggests the formation of a flavin semiquinone. 6. Flavin can be removed by treatment with acid ammonium sulphate, and activity can be restored to the inactive apoenzyme by addition of FAD, but not of FMN or riboflavin. 7. Studies of acceptor specificity showed that the enzyme has a relatively weak d-2-hydroxy acid oxidase activity.


The use of chymotrypsin as an adjuvant therapy in the treatment of tubercular pleural effusion.


Painless metastatic deposit in a finger presenting as a pulp infection with osteitis.


Alopecia areata, thyroid disease and autoimmunity.


Factitious wealing at the site of previous cutaneous response.


Sensitization by routine patch testing with ether extract of Primula obconica.


Chronic polymorphic light eruption (a study of 25 cases).


Percutaneous absorption of sodium fusidate and fusidic acid.


The vitamin B12 level in psoriatic skin and serum.


A case of hypersensitivity to corticosteroids.


An electron microscope study of the degranulation of rat peritoneal mast cells brought about by four different agents.


Vascular changes accompanying white dermographism and delayed blanch in atopic dermatitis.


Ureteroceles in disguise.

Ureteroceles in disguise.


Erythropoietic protoporphyria--a fatal case.


Theoretical considerations in the optimisation of dose distribution in radiation therapy.


Acro-osteolysis and bone fragility.

Acro-osteolysis and bone fragility.


Retroperitoneal accessory spleen simulating a suprarenal mass.


Large artery damage after x radiation.

Large artery damage after x radiation.


Pitfalls in the use of chromosome aberration analysis for biological radiation dosimetry.


PVP-stabilised indium sulphide colloid for liver and spleen scanning.


Leak testing of radioactive sources.

Leak testing of radioactive sources.


Angiography in the investigation of renal tumours.


Lymphography in renal tumours.

Lymphography in renal tumours.


Isotopic angiography using a gamma camera.


The place of radiotherapy in the treatment of hypernephroma.


An evaluation of the 70mm camera.

An evaluation of the 70mm camera.


The use of the 70 mm camera in coronary arteriography.


The radiological changes in closed injury of the chest.


Epidemiological changes in cancer incidence.


Suitable radioactive sources.

Suitable radioactive sources.


Clinical uses of 4-pi therapy.

Clinical uses of 4-pi therapy.


4-pi irradiation: the Cathetron.

4-pi irradiation: the Cathetron.


Experimental obstructive nephropathy in the pig. II. Pathology.


Experimental obstructive nephropathy in the pig. 3. Renal artery changes in experimental hydronephrosis, with special reference to renal artery stenosis due to fibromuscular hyperplasia.


Experimental obstructive nephropathy in the pig. IV. Experimental ureteric anastomosis in the pig.


Experimental obstructive nephropathy in the pig. V. Clinical and pathological applications.


Experimental obstructive nephropathy in the pig. I. Radiology.


Urological complications of pelvic surgery.


Post-operative recto-prostatic fistula.

Post-operative recto-prostatic fistula.


Urological complications of rectal surgery.


Urological complications of imperforate anus.


Bilateral ureteral injuries in gynaecology.


Urological problems following treatment of ovarian carcinoma.


A case of bilateral ureteric obstruction following obstetrical trauma.


The late urological complications of total hysterectomy.


The psoas bladder-hitch procedure for the replacement of the lower third of the ureter.


Ureteric replacement and recovery of renal function after pelvic surgery and irradiation in a patient with a uretero-peritoneal fistula.


The urological complications of Wertheim's hysterectomy.


The evolution of tumour cell populations in human bladder cancer.


The immediate response of bladder epithelium to injury by chemical carcinogens.


The aetiology of bladder tumours.

The aetiology of bladder tumours.


The pathogenesis of hydronephrosis in children.


Radical resection for tumours involving the posterior urethra.


Ileal conduit: acute obstruction of the uretero-ileal anastomosis.


The effects of anoxia, glucose, ATP, and ouabain on Na, K, and Cl in the rabbit lens.


Ocular hypotension in a population survey.


Ocular rigidity in tonography.

Ocular rigidity in tonography.


The colour of the optic disc.

The colour of the optic disc.


Kinetics of the pump-leak system of transport in the ocular lens, derived from classic enzyme kinetics and diffusion theory.


Transfer of D-isoascorbic acid and L-ascorbic acid into guinea pig eyes.


Cholinesterase isoenzymes in rabbit ocular tissue homogenates.


Development of quantitative perimetric tests.


Adaptation and the electrical excitability of the eye.


An automatic self-registering apparatus for the recording of global dark adaptation thresholds.


A contact glass with an adjustable indentor; description of a prototype.


Pseudofacility in untreated glaucoma.

Pseudofacility in untreated glaucoma.


The reversal of triparanol-induced cataracts in the rat.


Variation of acuity with luminance in ocular diseases and anomalies.


Physio-anatomy of the axial vascularisation of the optic nerve.


Studies on the visual evoked response: 3. Strabismus amblyopia and hysterical amblyopia.


A syndrome of iris nodules, ectopic Descemet's membrane, and unilateral glaucoma.


Norrie's disease in North America.

Norrie's disease in North America.


Ocular histopathologic changes in a case of a-beta-lipoproteinemia (Bassen-Kornzweig syndrome).


Proliferation of the juxtapapillary retinal pigment epithelium simulating malignant melanoma.


Linear systems analysis in the study of fluid dynamics in the eye.


The role of the astroglial cells in glaucomatous disc cupping.


Cup-disc ratio in early open-angle glaucoma.


Development of sickle cell retinopathy.

Development of sickle cell retinopathy.


Vascular opticopathy.

Vascular opticopathy.


Case studies in dyslexia.

Case studies in dyslexia.


Aspects of paralytic and comitant strabismus.


Fluorescein dynamics in the eye.

Fluorescein dynamics in the eye.


Lens subluxation and surgical aphakia treated with photocoagulation of the iris.


A photoelectric method for pupillary flow measurements.


Divergence excess and simulated divergence excess: diagnosis and surgical management.


Ultrastructure of the deep corneolimbal region.


Evaluation of the Fricke dosimeter with other dosimetry systems.


Importance of some methods of pasture feeding, of pasture type and of seasonal factors on 85Sr and 134Cs transfer from grass to milk.


Eosinophils.

Eosinophils.


Protein-bound carbohydrates and electrophoretogram of cerebrospinal fluid protein.


The African lymphoma in Central Africa.

The African lymphoma in Central Africa.


Lactose intolerance.

Lactose intolerance.


Light and electron microscopy on plasma cells and Russell bodies in the iris of a chronic uveitis patient.


The ocular immune response. 3. Effect of antilymphocyte serum on the development of immunogenic uveitis.


Retinal dystrophy in the rat--a pigment epithelial disease.


The electrically evoked response (EER) of the visual system. II. Effect of adaptation and retinitis pigmentosa.


Evaporation rate of water from the precorneal tear film and cornea in the rabbit.


Changes in the levels of free amino acids and myo-inositol in the galactose-exposed lens.


Mitotic activity in the cortical vitreous cells (hyalocytes) after photocoagulation.


Reality closeness, phantasy, and autokinesis: a dimension of cognitive style.


Self-concept therapy for adolescent females.


Subjective matching of anxiety to intensities of white noise.


Visual perception of sequential numerosity by normals and retardates.


Determinants of institutional release and prognosis in mental retardates.


Effect of hypnotic age regression on the magnitude of the Ponzo and Poggendorff illusions.


Psychopathology and semantic interpretation of ambiguous words.


The total synthesis of flulvoplumierin.

The total synthesis of flulvoplumierin.


Histologic post mortem evaluation of bone hyperplasia accompanying digital clavus.


The repair of bone following hammertoe surgery.


The pH of the fourth intertriginous area of the foot in Caucasians.


Molluscum contagiosum of the foot: a clinical note.


Hypoglycemia and burning feet.

Hypoglycemia and burning feet.


Influence of weight and nutrition upon muscle growth and intramuscular fat deposition in Holstein steers.


Effects of starter protein level on performance and body composition of pigs.


Effects of dietary levels of manganese and magnesium on performance of growing-finishing swine raised in confinement and on pasture.


Absorption and utilization of sugars by the baby pigs.


Response of growing-finishing swine to different housing environments during winter seasons.


Tonometer for measuring testicular consistency of bulls to predict semen quality.


Influence of season, sex and hormonal growth stimulants on feedlot performance of beef cattle.


Influence of graded levels of dietary iron, as ferrous sulfate, on performance and tissue mineral composition of steers.


Secretion of metabolites of vitamin A and B-carotene in the bile of sheep.


Ruminal volatile fatty acid concentrations in steers fed antibiotics.


Intake and digestibility of corn silages of different maturities, varieties and plant populations.


The structure of fatty acids from the antibiotic amphomycin.


Renal osteodystrophy.

Renal osteodystrophy.


Size-separation of yeast mitochondria in the zonal centrifuge. Mitochondria, released from yeast spheroplasts and subjected to rate separation through sorbitol gradients in the zonal centrifuge, migrated in a wide symmetrical zone. Electron micrographs showed that the mitochondria had been resolved within the zone according to size. The mean mitochondrial diameter at the leading edge was approximately twice that at the trailing edge of the particle zone. Activities of the enzymes cytochrome oxidase, malate dehydrogenase, and reduced nicotinamide adenine dinucleotide- and d-lactate cytochrome c reductases were essentially uniform throughout the mitochondrial zone. Mitochondria from a vegetative-petite mutant had almost the same size distribution as the isogenic wild type, but with somewhat larger mean diameter and either absent or markedly reduced enzyme activities. Mixtures of wild-type and petite mitochondria produced sedimentation profiles showing overlap of particle populations with respect to mean sedimentation rates and mitochondrial diameters, as well as intermediate levels of enzyme activities. Both cristate and noncristate organelles were present throughout the mitochondrial zone from these mixtures. Mitochondria centrifuged in sorbitol density gradients were well-preserved and yielded consistent sedimentation profiles, whereas particles in sucrose density gradients migrated more slowly, produced varied sedimentation profiles, and often showed spurious peaks, presumably due to particle aggregations.


Characteristics of virulent, attenuated, and avirulent Mycoplasma pneumoniae strains. Homologous pairs of virulent and attenuated or avirulent Mycoplasma pneumoniae strains were derived and compared in an effort to elucidate the mechanisms of virulence. These related strains were found to vary in growth, glycolysis, protein electrophoretic patterns, peroxide formation, morphology, and cytadsorption. Variations in the last two characteristics closely correlated with avirulence. This enables understanding of one stage in the pathogenic sequence and provides a convenient marker for avirulence. The derivation of infectious avirulent strains may make possible their use as live vaccines against M. pneumoniae disease.


Ultrastructural changes in bacteria isolated from cases of leprosy. One of two groups of rod-shaped bacteria (bacilli) isolated from cases of human leprosy have been found, under certain cultural conditions, to give rise to unusual phenotypes. In electron micrographs of ultrathin sections and negatively stained whole cells of these osmotically fragile bacteria, ultrastructural anomalies are apparent and seem to arise from disorder in the process(es) of septum formation or cell envelope biosynthesis or both. Two of the four strains examined are related to Corynebacterium acnes.


Ultrastructure of dimorphic transformation in paracoccidioides brasiliensis. The fine structure of Paracoccidioides brasiliensis undergoing temperature-dependent transformation from mycelium to yeast and vice versa (M right harpoon over left harpoon Y) was studied. The transitional form to mycelium from the yeast appears as an elongated bud that extends from the yeast and which has a mixture of characteristics from both the yeast and the mycelium. The transitional form to yeast from the mycelium starts with enlargement of the interseptal spaces and cracking of the outer electron-dense layer of the cell wall of the hypha. Later the interseptal spaces tend to become round and separate. In M --> Y only few interseptal spaces seem to transform. The yeast is produced by self-transformation of the hypha. In Y --> M a new structure is formed and the yeast dies. Intrahyphal hyphae are observed during the transformation from M --> Y, and intrayeast hyphae during the Y --> M. Due to the high mortality and breakage observed in both types of transformations, we believe that wound of the yeast or the mycelium could elicit this phenomenon.


Surface structure of Azotobactervinelandii cysts as revealed by freeze-cleaving. Micrographs of freeze-cleaved Azotobacter vinelandii cysts reveal that the surface is composed of several overlapping layers. This observation is consistent with the previously proposed structure of the outer cyst coat.


Transformation of Pasteurella novicida.

Transformation of Pasteurella novicida. Deoxyribonucleic acid from a streptomycin-resistant mutant of Pasteurella novicida transformed portions of P. novicida streptomycin-sensitive populations to streptomycin-resistant. Similarly, mutants auxotrophic for tryptophan or purine biosynthesis were also transformed to nutritional independence.


Antigenic characteristics of five species of human Bacteroides. The antigenic characteristics of five species of Bacteroides were determined by agglutination tests. No cross-reactivity among the species was observed.


Regulation of the meta cleavage pathway for benzoate oxidation by Pseudomonas putida. Catechol or 2-hydroxymuconic semialdehyde cannot participate as functional inducers of the meta pathway for benzoate metabolism in Pseudomonas putida. Induction of the first two enzymes of the pathway must be mediated by benzoate, or its analogues, as primary substrate.


Simplified method for testing mutagens in Saccharomyces. Pretreatment of yeast auxotrophs with mutagen on complete medium stimulates the reversion frequency.


Hydrogen metabolism by Rhodomicrobium vannielii. Under appropriate cultural conditions, cell suspensions of Rhodomicrobium vannielii effect two distinct photoreactions involving molecular hydrogen: (i) the photoreduction of carbon dioxide, and (ii) the photoproduction of hydrogen.


Effect of emulsion characteristics of a low-fat dairy spread on bacterial growth.


Vibrio enterotoxin in miniature pigs.

Vibrio enterotoxin in miniature pigs. Miniature pigs appear to be less sensitive than rabbits to cholera toxin introduced into segments of the ileum.


Effects of 131-I thyroid irradiation damage, thyroxine, and thiocyanate on radioiodine metabolism in dairy cows.


Reaction of Vibrio cholerae and choleragenic toxin in ileal loop of laboratory animals. Accumulation of fluid in the ligated ileal loop upon injection of cholera vibrios or choleragenic toxin seems to be a generalized phenomenon in laboratory animals.


Energy balance and excretion of DDT into milk.


Biosynthesis of milk.

Biosynthesis of milk.


Generalization gradients and stimulus control in delayed matching-to-sample. Neurological patients were subjects in delayed visual matching-to-sample. The sample and choice stimuli were ellipses of varying size. By measuring the difference in size between the sample on a given trial and the ellipse the subject chose on that trial, gradients of differences between samples and choice stimuli could be plotted. These difference gradients broadened with increasing delays. Sharp gradients were controlled by the samples. Flat gradients were controlled by features of the choice display, independently of the samples. Intermediate gradients reflected combined control by the samples and by the choice displays.


The presence of a temporal discrimination in the conditioned emotional response with humans. Six college students participated in matching-to-sample tasks. Conditioned emotional response (CER) training consisted of pairing a tone with a "painful" level of shock. Three of the subjects demonstrated response suppression, one subject showed facilitation, and two showed no change. Analysis of response rate during the tone interval indicated that, for those subjects who showed response suppression, the decrease in response rate was greatest immediately before onset of the unconditioned stimulus. This temporal discrimination was similar to that obtained with infrahumans.


Reinforcement of eye movement with concurrent schedules. Human macrosaccadic eye movements to two areas of a four-dial display were conditioned by concurrent variable-interval schedules of signals. Reinforcers (signals) were delivered to the two right-hand dials on one schedule and to the two left-hand dials on another, independent schedule. The use of a changeover delay between crossover eye movements and reinforcement had the effect of changing the pattern of scanning from fixating four dials in succession or in a Z-shaped pattern to scanning vertically the dials on either side with fewer crossovers. In the presence of a changeover delay, subjects matched relative eye-movement rates and relative reinforcement rates on each schedule. Rate of crossover eye movements, with a changeover delay in effect, was also inversely related to the difference in reinforcements arranged by the concurrent schedules. The results suggest that for stimuli whose critical components are arranged spatially, conditioned eye movements play an important part in selective stimulus control.


A light-activated scheduling system for complex visual discrimination training.


Behavioral discrimination of click intensity in cat. Avoidance conditioning procedures were used to train cats to discriminate intensity differences between successive clicks. The discriminative behavior was applied in a modified method of adjustment to determine a difference limen (DL) for click intensity. The obtained DLs were consistent within and between subjects, and averaged 4.4 db. This value is greater than previously reported intensity DLs for pure tones in cats.


A new technique for measuring thermoregulatory behavior in the rat. A tracking procedure was used to investigate the ability of rats to regulate their ambient temperature. Rats were placed in a chamber with two levers; depressions of one lever controlled a cold-water flow (11 degrees C) and the other controlled the flow of hot water (57 +/- 1 degrees C). If it alternated responses, the rat could regulate temperature within these two extremes. With training, this regulatory behavior resulted in a narrow environmental temperature range that approximated normal body temperature.


Combined action of diazepam and d-amphetamine on fixed-interval performance in cats. Cats trained under a fixed-interval 5-min schedule of milk presentation were injected with diazepam, amphetamine, and combinations of amphetamine and diazepam. Diazepam increased overall response rate as a function of the dose and disrupted the temporal pattern of responding. Low doses of amphetamine (0.5 mg/kg) usually increased the response rate; higher doses (1 to 2 mg/kg) either decreased the response rate or had little effect. Amphetamine always disrupted the temporal pattern of responding, even though it did not affect the overall rate. When doses of amphetamine that increased the response rate or left it unchanged were combined with diazepam, a potentiated increase in response rate occurred. When doses of amphetamine that decreased the response rate were combined with diazepam, the amphetamine-induced rate decreases were reversed at least partially. Less clear potentiation of disruption of the temporal pattern of responding was observed when amphetamine and diazepam were combined.


Adenosine deaminase phenotypes among sexual and parthenogenetic lizards in the genus Cnemidophorus (Teiidae).


Age-dependent changes in alcohol dehydrogenase in drosophila.


Effect of several hormones on the tolerance to glucose in the non diabetic stage of KK mice.


Is the Halsted radical mastectomy any longer indicated?


Causalgia.

Causalgia.


Effects of mammalian gonadotropins on the ovaries and oviducts of the lizard, Lygosoma laterale.


A machine scored medical examination form  for the state universities of Florida.


Group practice.

Group practice.


Uniform Anatomical Gift Act.

Uniform Anatomical Gift Act.


Linear growth kinetics of plaque-forming streptococci in the presence of sucrose.


The problem of the similarity of objects in numerical taxonomy.


Generation times of bacteria: real and artificial distributions.


Thiamine limited steady state growth of the yeast Cryptococcus albidus.


The supply of cholesterol and fatty acids for the growth of mycoplasmas.


Sources of carbon and energy used by Coprimus lagopus sensu Buller.


The partial purification and properties of endopolygalacturonase and alpha-L-arabino-furanosidase secreted by Sclerontinia fructigena.


Heart in cerebrovascular accidents.

Heart in cerebrovascular accidents.


Peptic ulcer.

Peptic ulcer.


Serum iron levels in jaundice in infancy and childhood.


Cold abscess in caries spine. A preliminary report.


Spontaneous subarachnoid haemorrhage.

Spontaneous subarachnoid haemorrhage.


I.M.A. Maternal Mortality Committee. Report for 1968.


Laboratory services.

Laboratory services.


Sacro-coccygeal chordoma.

Sacro-coccygeal chordoma.


Prevalence of urinary tract infection in Dublin school children.


Anticoagulant therapy in patients with cancer.


Spontaneous perforation of the oesophagus.


Caudal analgesia and anesthesia in obstetric practice.


Reactions to tetanus toxoid.

Reactions to tetanus toxoid.


From the files of the Committee for the Study of Maternal Mortality.


Antidepressant drugs.

Antidepressant drugs.


Hydroxyurea: a new agent for the management of refractory psoriasis.


Percutaneous catheterization of the subclavian vein in various clinical situations.


New glucose-6-phosphate dehydrogenase variants observed in Israel and their association with congenital nonspherocytic hemolytic disease.


Chloramphenicol and bone marrow mitochondria.


Effects of fasting and refeeding. II. Tubular sites of sodium reabsorption and effects of oral carbohydrate on potassium, calcium and phosphate excretion.


Comparative production of interferon by foreskin fibroblasts from newborn infants and children.


Analysis of organic compounds in human breath by gas chromatography-mass spectrometry.


Radioassay for serum vitamin B12 with the use of saliva as the vitamin B12 binder.


Serum heat stable alkaline phosphatase: an index of placental function.


The estimation of fetal maturity with retarded intrauterine growth.


Computer analysis of labour progression.


Serial analysis of plasma progesterone and pregnanediol in human pregnancy.


Cyclic changes in cervical mucus. 2. The role of saline.


Clinical and endocrinological studies with the isomeric components of clomiphene citrate.


Urinary testosterone and epitestosterone glucuroniside in hirsutism and certain menstrual disorders.


Adnexal inflammation and ureteric obstruction.


Ovarian function in congenital absence of the uterus.


Structure of mesuagin. A new 4-phenylcoumarin.


Evidence for dual innervation of the human extrinsic uterine arteries.


Delta-3 and delta-4 isomers of 4-alkyl-2-p-methoxybenzyl- L-methyltetrahydropyridines.


4-methoxy-1-methylpyridinium iodide. Grignard products and transformations thereof.


Formulation of multi-component eluents for laminar chromatography: amino acids on cellulose.


Technique aspects of carbohydrates.

Technique aspects of carbohydrates.


Estimation of euglobulin lysis time using a time-saving recorder.


Centrifugation of micro volumes using polythene tubing.


Simple, flexible, scale model of the DNA diad helix.


Genetic counselling.

Genetic counselling.


Sampler control of chart-drive for an autoanalyser.


Aspiration biopsy of localized upper-zone lung lesions.


The polymorphonuclear leucocyte count as an aid to the diagnosis of acute appendicitis.


Bed-sore control and a multi-purpose mattress.


Management of chronic renal failure by means of isolated jejunal loop dialysis.


Phenylbutazone and leukaemia. Is there a relationship?


An unusual case of bronchial obstruction.


Experiences with the cryosurgical treatment of epistaxis.


Electronically controlled wheelchair for a quadriplegic person.


The education of nurses in N.S.W.

The education of nurses in N.S.W.


Results of the F.F.A.R.A.C.S. examination and their effect in New South Wales on postgraduate teaching for the primary examination.


Specialists in Western Australian teaching hospitals.


Cancer of the bladder presenting as "cystitis" or "prostatism".


A new and effective treatment for acute vertigo and vomiting.


Hair grafting: a practical possibility.

Hair grafting: a practical possibility.


On specialization.

On specialization.


Puerperal thromboembolism and suppression of lactation by oestrogen.


The climates of change.

The climates of change.


Posterior ilio-psoas transplants for paralytic dislocation of the hips in a child with a lumbo-sacral meningocele.


Foetal distress during labour.

Foetal distress during labour.


Hospitals and the press.

Hospitals and the press.


'An old look at nursing and hospitals': a fable.


Ward housekeeping. 2. The ward housekeeper: a proposal based on organisational analysis.


This can happen again...

This can happen again...


A hospital is people.

A hospital is people.


Danger. Drivers at risk. 1.

Danger. Drivers at risk. 1.


'...and the eyes of the blind shall see'.


Nursing behind bars. 3. Pucklechurch Remand Centre.


Psychiatric nursing in Wales.

Psychiatric nursing in Wales.


Aspects of loving.

Aspects of loving.


Getting the best from others.

Getting the best from others.


Hope in the life of a child.

Hope in the life of a child.


Reflections on an early retirement.

Reflections on an early retirement.


Does the nursing profession need its own members of Parliament?


Danger. Drivers at risk. 2.

Danger. Drivers at risk. 2.


Reconstructive surgery in the anterior chamber.


Posttraumatic pseudophakia in children.

Posttraumatic pseudophakia in children.


Perforating and non-perforating acrylic corneal implants, including the Choyce 2-piece perforating kerato-prosthesis.


Combined implantations of the intraocular iris-clip-lens in post-traumatic lens opacifications and secondary cataracts.


Diagnosis and surgical correction of optic canal fracture after head injury.


Blow-out fractures of the orbit.

Blow-out fractures of the orbit.


Traumatic bitemporal hemianopsia.

Traumatic bitemporal hemianopsia.


Ophthalmic pathological findings in a case of thallium poisoning.


Cyanide induced optic neuropathy.

Cyanide induced optic neuropathy.


Visual load.

Visual load.


Are visual functions relevant to traffic safety?


Major injuries and rehabilitation.

Major injuries and rehabilitation.


Post-medical rehabilitation, why and how?


Changes in rabbit lenses following DMSO therapy.


The effects of oxygen on retinal circulation.


Casualties treated in the Eye Clinic of the Wilhelmina Gasthuis Amsterdam during a period of five years.


Replacement of iris prolapse after penetrating wounds of the eyes.


The early detection of chloroquine retinopathy with the Friedmann visual field analyser.


Phenothiazine retinopathy.

Phenothiazine retinopathy.


Fluorescein fundus angiography in chloroquine retinopathy.


Effect on the ERG of injecting N-ethyl maleimide into the eye after light adaptation.


Influences of some drugs on the ERG of the isolated rabbit retina.


On very short wavelength electroretinography. An original technique of diagnosis in infraclinical synthetic antimalarial retinopathies.


Some metabolic disturbances of the retina due to the effect of natrium fluoride.


Psychoanalytic or experiential group psychotherapy: a false dichotomy.


Electroretinographic and ganglion cell sensitivity in the isolated rat retina.


Psychotherapy of a male homosexual.

Psychotherapy of a male homosexual.


Psychotherapy with children of psychotherapists.


A psychotherapeutic corroboration of the meaning of the smiling response.


On form and similarity in mental functioning.


A note on M.D. Faber's essay "Suicide and the 'Ajax' of Sophocles".


Sexual symbolism and archeology.

Sexual symbolism and archeology.


An EEG study of the relationships between brain structures in rabbits under ethanol and d-amphetamine.


Selection and avoidance of alcohol solutions by two strains of inbred mice and derived generations.


Alcoholics at fault in fatal accidents and hospitalized alcoholics; a comparison.


A comparison of two treatment programs for alcoholics.


Alcohol and human physical aggression.

Alcohol and human physical aggression.


Response to alcoholics by the helping professions and community agencies in Denver.


The alcoholic game.

The alcoholic game.


Physician authoritarianism and the treatment of alcoholics.


Isolation of Salmonella stanleyville in Romania.


Acute haemorrhagic syndrome due to intravascular coagulation.


Why is the diagnosis of bronchopulmonary cancer made so late?


An instrument for biopsy of the buccal mucosa.


Erythropoietic protoporphyria (notes on a case).


Acute febrile states of tuberculous origin. Problems of diagnosis and treatment.


Prosthetic treatment of hereditary dentinogenesis imperfecta.


The cleavable hydatiform polycystic pseudotumoural disease.


Some pathogenic and clinical problems in nasosinusal allergy.


Stab wound sinography.

Stab wound sinography.


Immunoglobulins and acute phase reactants in man after major hepatic resection.


Sacrococcygeal pilonidal disease.

Sacrococcygeal pilonidal disease.


Immediate fistulotomy in the treatment of perianal abscess.


Control of epistaxis.

Control of epistaxis.


Mediastinoscopy.

Mediastinoscopy.


Arthrocentesis for diagnosis and therapy.


Gastrostomy.

Gastrostomy.


Carotid, vertebral, and brachial arteriography for extracranial lesions.


Treatment of nasal hemorrhage.

Treatment of nasal hemorrhage.


Brachial and radial artery cutdown.

Brachial and radial artery cutdown.


Plethysmography: a simple method of studying and following peripheral vascular disorders.


Tracheostomy.

Tracheostomy.


Scalene lymph node biopsy.

Scalene lymph node biopsy.


Central venous pressure technique.

Central venous pressure technique.


The creation of an artificial eustachian tube for otitis media.


Myringotomy.

Myringotomy.


Abdominal paracentesis.

Abdominal paracentesis.


Bronchoscopy in the sitting position.

Bronchoscopy in the sitting position.


Operative treatment of acute craniocerebral injuries.


Carotid angiography.

Carotid angiography.


Venography.

Venography.


Lymphangiography.

Lymphangiography.


Tube and trocar thoracostomy.

Tube and trocar thoracostomy.


Superior mediastinotomy: advantages over mediastinoscopy.


Esophagoscopy.

Esophagoscopy.


Central venous pressure monitoring: the subclavian approach.


Surgical treatment of bunions.

Surgical treatment of bunions.


Treatment of the ingrown toenail and a new anesthetic method.


Prevention of experimental rat caries. VI. Prevalence-extent relationship in experimental fissure caries in rats.


Excitatory and inhibitory components of somato-sympathetic reflex.


Biochemical maturation of the central nervous system. I. Lipid changes.


A model for the distribution of materials in the fluids of the central nervous system.


UDP-galactose-4-epimerase activity of developing mouse brain and liver extracts.


Uptake of gamma-aminobutyric acid by mitochondrial and synaptosomal fractions from mouse brain.


Epimerase-catalyzed glucose-galactose interconversion in the developing mouse brain.


The effects of environmental temperature and hypothalamic temperature on excretion of catecholamines in the urine of the pig.


Cortical representation of the ipsilateral chorda tympani nerve in the cat.


Composition of the corticofugal reflex.

Composition of the corticofugal reflex.


Rapid thermal cutaneous stimulation: peripheral nerve responses.


New fibers of sympathetic nature in the inner core region of Pacinian corpuscles.


Contact dermatitis due to an optical whitener in washing powders.


Inflammatory angiomatous nodules with abnormal blood vessels occurring about the ears and scalp (pseudo or atypical pyogenic granuloma).


Malignant atrophic papulosis (Degos' disease). Two cases occurring in the same family.


Pasteurella pseudotuberculosis as a cause of erythema nodosum.


Microscopic appearance of geographic tongue.


Studies on the mechanism of lymphocyte transformation inhibition in sarcoidosis.


Multiple defects of the hair shaft in Netherton's disease. Association with ichthyosis linearis circumflexa.


The abnormality of sweat duct function in psoriasis.


The etiology of tinea cruris in Karachi.


Iron deficiency and the oral mucous membrane.


Diurnal variation in transepidermal water loss.


Seasonal variation in the incidence of skin disease.


Psoriasis and anti-convulsant drugs.

Psoriasis and anti-convulsant drugs.


?Focal dermal hypoplasia; ?multiple cutaneous infarcts of the newborn.


Dermatitis from pollens and lichens.

Dermatitis from pollens and lichens.


Glucagon and the heart.

Glucagon and the heart.


Lung scanning.

Lung scanning.


End of an era.

End of an era.


Mental illness and the family doctor.

Mental illness and the family doctor.


Haemolysis in hepatitis and jaundice.

Haemolysis in hepatitis and jaundice.


Natural history of diverticular disease of the colon. A review of 521 cases. In a survey of the natural history of 521 patients with diverticular disease of the colon half of the patients had had symptoms for less than one month on presentation at hospital, and these carried the highest morbidity and mortality. Progression of the disease was usually within segments initially involved, and extension to other regions of the colon rarely occurred. The overall prognosis of patients with total colonic involvement was similar to those with localized disease, while the morbidity and mortality associated with a recurrent attack were higher than in the initial acute episode.


Reappraisal of clinical features of diverticular disease of the colon. In patients with diverticular disease of the colon factors which indicate a worse prognosis include widespread abdominal pain, nausea and vomiting, disturbed bowel habit, a palpable abdominal mass, abdominal distension, and any of the inflammatory complications. While radiology is of prime importance in the initial diagnosis, it is often impossible to differentiate between diverticulosis and diverticulitis. A more accurate distinction can be made by assessing all the available clinical, radiological, and pathological data, but again there are limitations and inaccuracies. The use of the term "diverticular disease" is preferable.


Blood pressure in a Scottish island community. A survey of mean blood pressure levels in age-and-sex-matched samples of the population of the island of Tiree appears to support the local belief that blood pressure is higher on the island than on the mainland. This conclusion may be related to the observation of a greater mean width of the heart, measured radiologically, in the island population compared with the mainland population. The greater mean body weight observed in the island compared with the mainland may be a factor. Blood pressure in men between the ages of 40 and 59 years is higher in Tiree than in selected samples in England and America.


Mammography in management of breast lesions. Comparison of the clinical and mammography findings in 101 histologically proved breast lesions showed that the accuracy of each method in diagnosing carcinoma was about 90%, but when taken together an accuracy of 98% was reached. Though mammography was less accurate in the diagnosis of benign lesions, it was found to be a valuable complement in the management of a lesion in the large atrophic breast and for showing an impalpable carcinoma. In mammography of the young dense breast a negative result must be interpreted with caution.


Percutaneous needle nephrostomy.

Percutaneous needle nephrostomy. Percutaneous nephrostomy is a simple technique for temporary drainage of an obstructed kidney. Under local anaesthesia a ureteric catheter is passed through a Vim-Silverman needle into the renal pelvis and is connected to a drainage bag. Seven cases (six successful) in which this method was used are described and the indications are discussed. It has been free from complications, is acceptable to patients, and is felt to represent a useful addition to the methods available for the treatment of obstruction of the upper urinary tract.


Acute post-streptococcal toxaemic renal failure.


Facial pain.

Facial pain.


Glucagon and haemodynamics of acute myocardial infarction. Glucagon was administered to six patients with acute myocardial infarction. Three of them had cardiogenic shock syndrome. Glucagon produced a positive inotropic response in all cases, which resulted in a significant rise in blood pressure, with only slight chronotropic effect. No arrhythmias were induced, and all patients with cardiogenic shock improved temporarily. Further evaluation of glucagon in shock syndrome to determine the dose and method of administration is required.


Fluids for intravenous infusion.

Fluids for intravenous infusion.


Deep vein thrombosis. Diagnosis.

Deep vein thrombosis. Diagnosis.


Deep vein thrombosis: medical management.


"Five-day courses" and respiratory infections.


Deep vein thrombosis: surgical management.


Hiatus hernia and reflux oesophagitis.

Hiatus hernia and reflux oesophagitis.


Spironolactone in hyperaldosteronism.

Spironolactone in hyperaldosteronism.


Fibrinolysis and toxaemia of pregnancy.

Fibrinolysis and toxaemia of pregnancy.


Anaesthesia in the dark.

Anaesthesia in the dark.


Mutants of influenza virus.

Mutants of influenza virus.


Steroids and sarcoid.

Steroids and sarcoid.


Synovectomy of the knee in rheumatoid arthritis.


Switching pills.

Switching pills.


Syringomyelia and cavities in the cord.

Syringomyelia and cavities in the cord.


Family planning services.

Family planning services.


Ten-year haematological follow-up: mortality and haematological changes. In a 10-year follow-up study of 543 men and 180 women seen in a community survey in 1958 mortality was examined in relation to the 1958 haematological data, and 91% of the survivors were re-examined. Analyses based on the 1958 haemoglobin and packed cell volume estimations suggested that those with values near the mean may subsequently have lower death rates. Higher death rates occurred in those having low serum iron levels. Comparisons of haemoglobin concentrations and of packed cell volumes in 1958 and 1968 show correlation coefficients (r) between 0.30 and 0.60 in various subgroups.


Results of treatment of dermatitis herpetiformis with a gluten-free diet after one year. Twenty-one patients with dermatitis herpetiformis initially controlled by dapsone or sulphonamides have been treated with a gluten-free diet and reassessed at intervals for up to 15 months (mean 11.9 months). According to routine histological and dissecting microscope criteria the small-bowel lesion improved in 10, but when mean epithelial cell height was used as a measure 15 patients improved. Five of the patients with diarrhoea improved after withdrawing gluten from the diet but none reverted to completely normal bowel habit. The tests for malabsorption showed little improvement in the treatment period. Twelve patients needed less dapsone to control their skin complaint, the mean dose falling from 144 mg. to a mean of 70 mg. per day; of these three stopped using this drug altogether.


Intravenous glucose tolerance, insulin, glucose, and free fatty acid levels after myocardial infarction. Glucose tolerance tests performed on 12 patients within 15 hours of myocardial infarction and repeated two to four weeks later showed failure of insulin secretion, hyperglycaemia, glucose intolerance, and high free fatty acid levels. More pronounced changes were found in patients with cardiogenic shock. These findings suggest that the therapeutic use of potassium, glucose, and insulin should be re-evaluated.


Assessment of platelet production with 75Se selenomethionine. Incorporation of intravenously injected (75)Se selenomethionine into platelets has been found to vary with alterations in the rate of platelet production. It appears to label newly produced platelets during their formation in megakaryocytes and provides a method by which thrombopoiesis may be studied in vivo. This technique may be applicable to clinical studies of disordered platelet production.


Alcoholic myopathy.

Alcoholic myopathy.


Recurrent virus meningitis.

Recurrent virus meningitis.


Changing oral contraceptives.

Changing oral contraceptives.


Study of patients' psychological attitudes to a coronary care unit. Seventy-four consecutive male patients aged 38 to 63 years were admitted to a coronary care unit with their first myocardial infarction. Their attitude to the unit was studied by interview and personality tests. Only six patients found the unit anxiety-provoking. Dependency feelings were found to occur frequently, both after transfer from the unit to the general wards and after discharge from hospital. It is suggested that the weaning process from the unit should be gradual and that at least one follow-up outpatient appointment should be arranged, as well as good liaison between the family doctor and the hospital.


Some features of traffic accidents.

Some features of traffic accidents. Some aspects of urban and rural traffic accidents have been studied at the scene of some accidents in Birmingham and the county of Worcestershire. Accidents to pedestrians are essentially an urban problem, occur mainly at low speed, and most of the serious injury comes from the initial contact with the vehicle, rather than from secondary impacts with the road surface. The characteristics of motor-cycle accidents are more varied; in urban areas there are many side impacts, with consequent injury to the lower limbs, while rural collisions are predominantly front on, with a high incidence of head injury. Accidents to car occupants vary according to the environment.


Life cycle of toxoplasma gondii.

Life cycle of toxoplasma gondii.


Mental problems in rheumatoid arthritis.


Unusual effect of fenfluramine.

Unusual effect of fenfluramine.


Heat and the I.U.C.D.

Heat and the I.U.C.D.


Length of a lippes loop.

Length of a lippes loop.


Epilepsy and folate deficiency.

Epilepsy and folate deficiency.


Serological evidence of infection with A2 Hong Kong influenza virus during the epidemic in Britain 1968-9.


Death from paraquat.

Death from paraquat.


Nurses committed for trial.

Nurses committed for trial.


Studies on the antigenic structure of human and hog intrinsic factors.


Measurement of antibody-producing capacity in man. I. The normal response to flagellin from Salmonella adelaide.


Preliminary observations on the effect of heterologous anti-lymphocytic globulin on autologous immune complex nephritis in rats.


Antibodies to nucleoprotein and to hydrazide-altered soluble nucleoprotein in tuberculous patients receiving isoniazid.


Study of the effect of a dihydromorphanthridine derivative in Parkinson's disease.


Liver damage and isoniazid allergy.

Liver damage and isoniazid allergy.


Encephalitis with ophthalmoplegia.

Encephalitis with ophthalmoplegia.


Cephalothin v. cephaloridine.

Cephalothin v. cephaloridine.


Treatment of generalized epilepsy with acrisuxine.


Surgery for chronic gingivitis and periodontitis.


Serum sialic acid in rickets and osteomalacia.


A case of double superior vena cavae along with an apical septate lobe of the lung.


A single left sided inferior vena cava.

A single left sided inferior vena cava.


Effect of intrauterine foreign body on pregnancy and pseudopregnancy of rats.


Polymers as bearing materials for total hip replacement: a friction and wear analysis.


Corrosion under stress of materials composing dental amalgam.


Membrane resistance of semipermeable microcapsules.


Nonthrombogenic surface preparation for silicone rubber.


Thrombogenicity of some biomedical materials: platelet-interface reactions.


Enzymatic and electrochemical polymerization of fibrinogen.


Electrosorption of amino acids peptides and proteins in relation to the compatibility of materials and the human body.


Electrochemical power sources for pacemakers: electrocatalytic investigation of various oxygen cathodes using stainless steel anodes.


Crosslinking of ionotropic protein symplexes by sulfur bridges.


The measurement of cell adhesiveness by an absolute method.


Embryonic development of the heart. II. Formation of the epicardium.


The role of movement in the development of joints and related structures: the head and neck in the chick embryo.


Epithelial and mesenchymal cell interactions with extracellular matrix material in vitro.


The differentiation capacity of isolated loach (Misgurnus fossilis L.) blastoderm.


Ontogenetic changes in hemoglobin synthesis of two strains of Chironomus tentans.


Biophysical considerations of some problems in tympanoplasties.


A practical alternative to combined approach tympanoplasty.


Fate of primordial germ cells in the transplanted hind gut of mouse embryos.


Unusual complications of tonsil and adenoid removal.


Probability of perceptive deafness in obliterative otosclerosis undergoing re-operation.


Relation of the otosclerotic focus to the fissula ante-fenestram.


Neonatal nasal septal deformities.

Neonatal nasal septal deformities.


A case of nasal neurilemmoma.

A case of nasal neurilemmoma.


An unusual foreign body in the retro-pharyngeal space.


Deafness following acute carbon monoxide poisoning.


Adenolymphoma in a laryngocoele.

Adenolymphoma in a laryngocoele.


Effect of the methylation of the 2'-hydroxyl groups in polyadenylic acid on its structure in weakly acidic and neutral solutions and on its capability to form ordered complexes with polyuridylic acid.


Refinement of protein conformations using a macromolecular energy minimization procedure.


Fractions of HeLa DNA differing in their content of guanine+cytosine.


Calibration of molecular weight scales for DNA.


Structure of crystalline alpha-chymotrypsin. 3. Crystallographic studies of substrates and inhibitors bound to the active site of alpha-chymotrypsin.


Regional blood flow in the normal cerebral hemisphere.


A feasibility study of a screening test for abnormalities of carotid blood flow using Technetium-99m.


Intracranial thrombosis of the internal carotid artery after closed head injury.


Interhemispheric subdural daematoma: a case report.


Perinatal telencephalic leucoencephalopathy.


A procedure for the determination of thresholds in impaired sensory fields.


Reversal of the glabellar reflex in Parkinsonism by L-dopa.


An unusual case of neuroma of the median nerve.


Haemangiopericytoma of the pineal body.

Haemangiopericytoma of the pineal body.


L-dopa and the negative symptoms of Parkinsonism.


The effects of hypoxia on the excitability of the isolated peripheral nerves of alloxan-diabetic rats.


Clinical investigation of lesions of the visual pathway: a new objective technique.


Subcellular distribution and possible nature of the binding for 14C-dibenamine and 14C-propanolol in the CNS.


Evidence for a cholinergic influence on pineal hydroxyindole O-methyltransferase activity with changes in environmental lighting.


Electrical measurements of changes in the passive permeability of the small intestine during ontogeny.


The effect of some monoamine oxidase inhibitors on gluconeogenesis.


The influence of light on daily rhythm in hepatic drug metabolizing enzymes in rat.


Effects of guanethidine on rat brain serotonin and norepinephrine.


The mode of potassium action on the adrenergic neuron amine transport system.


Recording of the respiratory process in mice without strain on the respiratory organs.


The effect of calcium ion on hypotonic hemolysis of human erythrocytes.


Molecular biology of aging.

Molecular biology of aging.


Metabolism of mono- and diacyl esters of tropane-3 alpha, 6 beta-diol in the Solanaceae.


Minimum number of hemopoietic cells needed to preserve life in mice.


Phytochrome-mediated repression of enzyme increase in mustard seedlings.


Antigens and antigenicity.

Antigens and antigenicity.


Nihilistic effect of 2 positive chemical stimuli.


Effect of biotin on the fertility of the yellow fever mosquito, Aedes aegypti (L.).


Inhibition of plant growth by thermal polylysine.


Isolation on intact mitochondria from sugar beet leaves.


Value of adenine, various nucleosides, and ouabain in maintenance of integrity of red blood cells under blood bank conditions.


Antigenic markers on cultured human cells. 3. The MN antigens.


Serotyping for homotransplantation. 28. Sib-pair assay for nonHL-A antigens.


A simple method for freezing of lymphocytes with retained viability.


First example of Nya blood group antigen in American population.


Absence of close linkage between the locus for Xg and the locus for anhidrotic ectodermal dysplasia.


Blood group antibody notation.

Blood group antibody notation.


Acrylamide gel electrophoretic analysis of adenohypophyseal STH and LTH in androgenized male and female rats.


Reactivity of the subcutaneous pituitary graft in chicken embryos treated with propylthiouracil.


Accessory parathyroid tissue in the rat thymus. Electron- and light-microscopic autoradiographic studies.


Histochemical evidence of direct neuronal pathways in Anodonta cygnea L.


Hemodynamic alterations in acute myocardial infarction with shock.


Relieving angina.

Relieving angina.


Early phase of myocardial ischemic injury and infarction.


Acute coronary occlusion: early changes that induce coronary dilatation and the development of collateral circulation.


Biochemical aspects of early myocardial ischemia.


Heterogeneity of coronary blood flow in human coronary artery disease and experimental myocardial infarction.


The clinical significance of bradycardic rhythms in acute myocardial infarction.


Pathogenesis of arrhythmias in acute myocardial infarction.


Pre-hospital management of acute myocardial infarction.


Sinoventricular conduction and its relation to sinoatrial conduction.


Pathogenesis of arrhythmias in myocardial infarction.


Correcting arterial hypoxemia by oxygen therapy in patients with acute myocardial infarction. Effect on ventilation and hemodynamics.


Fetal risk with the use of coumarin anticoagulant agents in pregnant patients with intracardiac ball valve prosthesis.


The effect of diazoxide on coronary blood flow.


Management of severe hypertension with intravenous injections of diazoxide.


Smoldering myocarditis with intermittent complete A-V block and Stokes-Adams syndrome. A histopathologic and electrocardiographic study of "trifascicular" bundle branch block.


Incomplete bilateral bundle branch block. A simplified diagram for its recognition.


Estrogen metabolism in patients at high risk for endometrial carcinoma. I. Urinary metabolites of H3-estradiol in normal postmenopausal women and those with endometrial carcinoma. Of 51 patients more than 2 years beyond the menopause, 34 had a diagnosis of endometrial carcinoma.  Any with liver involvement were not included.  14 were found to have abnormal glucose metabolism.  Each patient received an intravenous infusion of 8 mcc of bata-6, 7H-3 dissolved in 10 cc of 10% propylene glycol.  96 hour urine collections were obtained by an indwelling catheter.  Values for the recovery of radioactivity associated with estrone, estradio, estriol, and estriol/estrone + estradiol expressed in percent of injected radioactivity are given.  A wide range of values was obtained and great variations in ratios.  Generally the results were similar to those obtained from studies on menstruating females.  There was no significant difference between patients with or without endometrial carcinoma in terms of recovered radioactivity or of the estriol quotient.  However, methoxgestrone, epiestriol, and the alpha-ketols which make up a significant portion of theurinary metabolites of estradiol 17 beta were not studied.  Restudy of 6 patients with carcinoma produced constant patterns of metabolism.  A significantly lower specific activity of estriol as compared to that of estrone was demonstrated in both groups of patients when estradiol 17 beta had been administered.  However, this difference was less precursons of urinary estriol.  Androstenedione may be one of these.  Reasonable radiochemical purity of each final metabolite was verified by recrystallization to constant specific activity following the addition of nouradioactive estrone or estriol.


Clinical biochemical, and experimental studies on lactation. IV. Quantitative and qualitative changes induced in goat's milk by gestagens.


Suprapubic cystotomy with a polyethylene tube.


Current thoughts on the management of dysfunctional uterine bleeding.


Effect of radium treatment on the enzyme content of vaginal fluid in cervical cancer.


Prognostic significance of radiographic ureteropathy before and after irradiation therapy for carcinoma of the cervix uteri.


A vasodepressor substance of the human placenta. The authors of this article have been able to isolate from the human placenta large amounts of a vasodepressor substance able to cause relaxation of the duodenum, and decrease blood pressure in rats.  The vasoactive substance was obtained only by extraction with dichloroacetic acid, hydrochloric acid, and with methylene chloride, but not with aqueous extract, or by ether, ethanol, or acetone extraction.  The substance is not a peptide; it may be either a prostaglandin such as PGE1, or may be related to this group.  Normal placenta usually yield more vasodepressor material than toxemic placenta.


Relationship between length of gestation and cervical dilatation, uterine contractility, and other factors during pregnancy.


Some significant obstetric trends in a metropolitan area.


Effects of certain psychotropic drugs on immunologic pregnancy tests.


Pathogenesis of tubal pregnancy.

Pathogenesis of tubal pregnancy.


Maternal heart volume and prematurity.

Maternal heart volume and prematurity.


Fetal leukocyte pattern in premature rupture of amniotic membranes and in normal and abnormal labor.


Unilateral gonadoblastoma in a pregnant woman.


Amebiasis of the female genital tract.

Amebiasis of the female genital tract.


Metallic copper as an intrauterine contraceptice adjunct to the "T" device. 605 women were inserted with plain T-IUDs, 508 patients were inserted with TCu-A devices, and 279 women were inserted with TCu-B devices.  In the TCu-A, a 2 cm length of copper wire of .5 mm diameter was wound around the upper aspect of the vertical arm of the T-IUD.  In the TCu-B, a 6 cm length of wire of .15 mm diameter was coiled downward over a 1 cm distance.  The surface area of copper was 30 mm in both prototypes.  The data derived from the 3 series of patients were tabulated and analyzed utilizing the Life Table method of Tietze.  Endometrial biopsies were obtained from randomly selected patients.  Results showed that after 2 years of use, the plain T device had a significantly lower rate of metrorrhagia than had been reported for any other contraceptive device.  The rate was approximately 6 times less than that observed with the Lippes loop D.  Pain was a negligible cause for closure during the 2 year period.  The T device had a rate of pregnancy of 24.3 which is 6 times the pregnancy rate of the Lippes loop D.  The first expulsion rate was 4.5, but the rate for later expulsions was .4.  When a small qlantity of copper was added to the T there was a dramatic and highly significant reduction in the rate of pregnancy.  At the end of 2 years of use the rate was 9.8 for the TCu-A.  Other clinical parameters also were apparently modified by the metallic copper.  The expulsion rate was reduced, the rate of metrorrhagia was slightly increased, and the rate of pain may have been increased.  During the same lenght of time the rate of removal for loop D because of bleeding and/or pain is approximately 3 times greater than for the T with copper.  Reductions in both expulsion and removal rates of TCu because of medical reasons constituted the principal factors accounting for the continuation rate of 77.6 as compared with 65.6 for loop D at the end of 2 years of use.


Perforation of a puerperal uterus with two Lippes loops.


Sebaceous metaplasia of the human cervix.


Fluorescein angiography of malignant melanoma of the choroid.


Unilateral proptosis secondary to orbital mucocele in infancy.


Peripapillary staphyloma with respiratory pulsation.


An autoradiographic study of the effect of neuraminidase or trypsin on transfused lymphocytes.


Subcellular localization of sodium in normal and injured proximal tubules of the rat kidney.


Some alterations in hepatic cytosome structure and acid phosphatase activity induced by DL-ethionine.


The effect of leukocyte antiserum on the generalized Shwartzman reaction.


Fine structural alterations in thyroid parafollicular cells of cows in response to experimental hypercalcemia induced by vitamin D.


Effect of native levan on membrane permeability. I. Effect on the vascular membrane in acute nonspecific inflammation: a study with the light microscope.


Influence of cirrhosis on production of atheroarteriosclerosis and thromboarteritis with vitamin D and dietary cholesterol.


Teaching science in Ethiopia.

Teaching science in Ethiopia.


The synthesis of an enzyme.

The synthesis of an enzyme.


Early changes in livers of rats fed choline-deficient diets at four levels of protein.


Chemical systems and chemical evolution: the philosophy of molecular biology.


Memory-scanning: mental processes revealed by reaction-time experiments.


Time and the earth.

Time and the earth.


The scientific community and the crisis of belief.


Acausal phenomena in physics and biology: a case for reconstruction.


Federal research problems.

Federal research problems.


The public perception of protest.

The public perception of protest.


Ecological analysis of delinquency: aggregation effects.


Clinical and laboratory features of epidemic St. Louis encephalitis.


Interferon in human infections with St. Louis encephalitis virus.


The response of patients with "idiopathic" obstructive pulmonary disease and "allergic" obstructive bronchitis to prednisone.


Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?


Serum vitamin B12 content and unsaturated vitamin B12-binding capacity in myeloproliferative disease. Value in differential diagnosis and as indicators of disease activity.


The kallikreinogen-kallikrein enzyme system of human plasma. Assay of components and observations in disease states.


Consumption coagulopathy in miliary tuberculosis.


Prolonged survival in lymphangitic carcinomatosis.


Ultrasound for the diagnosis of atrial tumor.


Anticoagulants in acute myocardial infarction: the last (?) word.


Calcitonin--a progress report.

Calcitonin--a progress report.


Underemployment of women physicians.

Underemployment of women physicians.


Percussion of the liver.

Percussion of the liver.


Oral solutions for cholera.

Oral solutions for cholera.


Intraperitoneal loss of a dialysis catheter.


Functional or organic? a pointless question.


Idiopathic proteinuria.

Idiopathic proteinuria.


Standardization of the oral glucose-tolerance test.


Serum creatine kinase as a test of thyroid function.


Terminology of pulmonary function.

Terminology of pulmonary function.


Glomeruli: local and focal.

Glomeruli: local and focal.


Lung cancer and surgery.

Lung cancer and surgery.


Methotrexate in sarcoidosis.

Methotrexate in sarcoidosis.


Hypertension induced by oral contraceptives containing estrogen and gestagen. Effects on plasma renin activity and aldosterone excretion.


The renal clearance of amylase in renal insufficiency, acute pancreatitis, and macroamylasemia.


Paroxysmal atrial fibrillation in heroin intoxication.


Quinidine excretion in aciduria and alkaluria.


Miosis, trismus, and dysphagia. An unusual presentation of temporal arteritis.


Rat-bite fever. Report of three cases.

Rat-bite fever. Report of three cases.


Treatment of early mammary carcinoma: a cooperative international study.


Total mastectomy with axillary dissection and irradiation for mammary carcinoma.


Conservative radial mastectomy (Patey's operation).


Erythema annulare centrifugum (Darier).

Erythema annulare centrifugum (Darier).


Nonlinear relationship between averaged electromyogram potential and muscle tension in normal subjects.


Electromyographic evidence of lower motor neuron involvement in hemiplegia.


Morphology, innervation, and electromyographic study of the erector spinae.


Silent period during isometric and isotonic contraction.


Effects of axillary nerve block on muscle force in the upper extremity.


Practical graded exercise program after myocardial infarction.


Safe exercise after myocardial infarction.


Hematopoiesis and serum iron changes following vincristine sulfate.


A study of the sickling phenomenon and oxygen dissociation curve in patients with hemoglobins SS, SD, SF and SC.


Early development of injection-site sarcomas in rats: a study of tumours induced by iron-dextran.


Mesotheliomas in rats following inoculation with asbestos.


The application of a mathematical model describing the times of occurrence of mesotheliomas in rats following inoculation with asbestos.


Effect of oral copper sulfate on 7,12-dimethylbenz(alpha)anthracene carcinogenesis in mice.


The vascularisation of Brown-Pearce carcinoma implanted in rabbit liver.


Aflatoxin induced lesions in Syrian hamsters.


The effects of oestrogens and progestins on the response of mice to barbiturates. 1. Mestranol (oestrogen) prolonged, whilst lynestrenol (progestin) reduced, the duration of pentobarbitone and hexobarbitone sleep in mice, whilst the effects of barbitone were not altered.2. The effects of these steroids on pentobarbitone sleep were dose-related, did not show tachyphylaxis, and produced optimal effects after only 4 days pretreatment.3. The effects of lynestrenol were abolished by SKF 525A, whilst those of mestranol were markedly potentiated, suggesting a different mechanism and/or locus of action for mestranol and SKF 525A.4. Examination of plasma levels of pentobarbitone in mice pretreated with mestranol, lynestrenol or SKF 525A showed that lynestrenol increased whilst mestranol and SKF 525A reduced the rate of clearance of barbiturate from the plasma.5. The effects of lynestrenol disappeared when pentobarbitone was prevented from inducing hypothermia, whilst some significant prolongation of pentobarbitone sleep persisted in mestranol treated mice. This suggested that the ability to potentiate hypothermia was not the sole mechanism by which the effects of pentobarbitone were enhanced by mestranol.6. It is concluded these steroids alter the duration of action of pentobarbitone (and hexobarbitone) by changing the rate of barbiturate metabolism. In the case of mestranol, this might be a combination of an effect upon basal metabolic rate (enhancing hypothermia) and a direct effect on the liver. An effect upon renal clearance cannot be excluded by these results.


Polarographic assay of monoamine oxidase.


The tatooed psychiatric patient.

The tatooed psychiatric patient.


Theory and technique of the repertory grid.


The diagnostic distribution of treated psychiatric illness in Lebanon.


Role of adrenal hormones in the synthesis of noradrenaline in cardiac sympathetic neurones. 1. Adrenalectomy or adrenal demedullation affected neither the levels of endogenous catecholamines in the rat heart nor the accumulation of (3)H-noradrenaline 1 hr after its intravenous administration.2. Twenty-four hours after intravenous administration of labelled amine, however, its retention was markedly reduced in the heart of adrenalectomized or demedullated rats. Ganglionic blockade prevented this reduction.3. Rate calculations from the decline of catecholamine levels after blockade of synthesis with alpha-methyl-tyrosine showed that cardiac synthesis of noradrenaline increased about four-fold after demedullation and about three-fold after adrenalectomy. This increase in synthesis may compensate for the loss of circulating catecholamines.4. There was no change in catechol-o-methyl-transferase activity, but monoamine oxidase activity was increased in the homogenates of the heart of adrenalectomized and demedullated rats. The increase in the cardiac monoamine oxidase activity was markedly greater in the adrenalectomized rats than in the demedullated rats.5. It is suggested that adrenal cortex insufficiency may modulate the rate of synthesis of noradrenaline and monoamine oxidase activity in cardiac sympathetic neurones.


The physiology of faith.

The physiology of faith.


Acute psychotic episodes in patients treated with fluphenazine enanthate.


Dermatoglyphics and schizophrenia.

Dermatoglyphics and schizophrenia.


A quantum-theoretic approach to enzyme specificity: proposals for a new type of biochemical control mechanism.


Comparison of mathematical models for cat lung and viscoelastic balloon derived by Laplace transform methods from pressure-volume data.


A tumor cell model for the determination of drug schedules and drug effect in tumor reduction.


A model of population fitness and the maintenance of genetic polymorphism when two ecological patches are available.


Hydrodynamics of bolus flow--an analytical approach to blood flow in capillaries.


Models for the pressing rate response of rats and pogeons on a certain class of variable interval schedules of behavior.


On the theory of the spatial organization of macromolecules in connective tissue.


Models for reserpine effects on normal and brain-operated animals on a continuous reinforcement bar pressing schedule.


Some conditions for sustained oscillations in biochemical chains with feedback inhibition.


Action of pyridine-2-aldoxime methochloride (PAM) on the rectus abdominis muscle of the frog.


The strandedness of nucleic acids.

The strandedness of nucleic acids.


Transmembrane potential and force of contraction of the normal and potassium-deficient human atrial tissue in vitro.