Knee extension. Measurement of the isometric force in different positions of the knee-joint.


Reflex inhibition of the quadriceps elicited from a subperiosteal tumour of the femur.


Treatment of delayed union and non-union of the tibia by fibular resection.


Chemiluminescence in dosimetry.

Chemiluminescence in dosimetry.


The value of forced inspirogram for estimating reversibility of ventilatory impairment chronic obstructive lung disease.


Purification and some properties of muscle AMP-aminohydrolase from carp (Cyprinus carpio).


The reaction of azlactone with chymotrypsin and trypsin.


Inhibition of RNA synthesis by 9-aminoacridine in regenerating rat liver and cell culture.


influence of a cationic detergent on the development of infection in experimental wounds contaminated with staphylococci.


Immunosuppressive treatment in non-transplanted dogs. Azathioprine versus azathioprine-antilymphocyteimmuno-globulin-G.


Reaction of the venous wall to experimentally induced thrombi.


Buerger's disease in Israel. Investigations on carboxyhemoglobin and serum cholesterol levels after smoking.


Fracture dislocations of the shoulder joint. Four cases treated with vitallium prosthesis.


Carcinoma of the pancreas. Biopsy or not?


Vascular changes within the liver in biliary obstruction.


Mucosal hyperplasia of the gallbladder in cases of cholecystolithiasis.


Carcinoma of the extrahepatic bile ducts. Report of nine cases.


Surgical indications in Meckel's diverticulum.


Appendiceal abscess-acute appendectomy or conservative treatment.


Appendiceal peritonitis in children. A ten-year case material.


Malignant tumours of the small intestine.


Stercoraceous perforation of the colon. Case report.


Echinococcosis unilocularis hepatis with cyst rupture into the biliary ducts. Report of a case.


Fibrinolytic activity in healing wound.

Fibrinolytic activity in healing wound.


Relation between cystic fibroadenomatosis and cancer of the breast.


Comparison of lipolysis in human subcutaneous and omental adipose tissue with regard to effects of noradrenaline, theophylline, prostaglandin E1 and age.


Intravascular coagulation in the lungs in experimental fat embolism.


Fatigue fracture of the first rib.

Fatigue fracture of the first rib.


Evaluation of transluminal recanalisation of the femoral artery.


Two-stage operation for the production of intermittent claudication in dogs.


Reversal of the venous circulation through the canine liver.


The effect of vagotomy on gall bladder and duodenal pressures during rest and stimulation with cholecystokinin.


Evaluation of conservative treatment of acute cholecystitis.


Gallstone ileus. A report of 22 cases.

Gallstone ileus. A report of 22 cases.


Gallstone ileus.

Gallstone ileus.


Comparison between the effect of pentagastrin and histamine on gastric acid secretion.


Fatal necrosis of the left colon following iliofemoral thromboendarterectomy. Case report.


Malignant melanoma of the anal canal. Report of two cases.


Stereotypes according to ethnic origin, social class and sex.


Personality attributes associated with two measures of cognitive style.


The role of the felt position of the head in the audiogyral illusion.


A cross-cultural study of belongingness, anxiety and self sufficiency.


A study of the Bender Gestalt figures and visual perception.


Bufotenine in human urine.

Bufotenine in human urine.


CNS effects of local anesthetics only partially dependent on biogenic amine mechanisms.


Congeners of gamma-hydroxybutyrate in relation to depressant and convulsant activity.


Neuropharmacological analysis of agonistic actions of cyclazocine in rabbits.


Changing concepts of the function of sleep: discovery of intense brain activity during sleep calls for revision of hypotheses as to its function.


Auditory or visual deafferentation and cerebral epileptogenicity.


The present pattern of paediatrics in Britain. Introduction.


The magnitude of pitch inflection.

The magnitude of pitch inflection.


The present pattern of paediatrics in Britain. The present role of the general practitioner in the medical care of children.


The present pattern of paediatrics in Britain. The local authority child health services.


The present pattern of paediatrics in Britain. The work of consultant paediatricans employed by regional hospital boards.


The present pattern of paediatrics in Britain. The work of the full-time consultant paediatrician employed by a university.


The role and training of paediatricians in Britain. Undergraduate education.


The role and training of paediatricians in Britain. Student attitudes.


The role and training of paediatricians in Britain. Postgraduate training of consultant paediatricians.


The role and training of paediatricians in Britain. Continuing education of consultant paediatricians.


The role and training of paediatricians in Britain. Paediatric education for doctors in other branches of medicine and for non-medical colleagues.


The future of paediatric care in Britain. The future of paediatric care in general practice.


The future of paediatric care in Britain. The work of an "attached" health visitor.


The future of paediatric care in Britain. The future of community paediatric care.


The future of paediatric care in Britain. Specialist paediatrics: surgery.


The future of paediatric care in Britain. The future rôle of the regional paediatrician.


The future of paediatric care in Britain. The relevance of research to paediatric care.


The future training of consultant paediatricians. The knowledge, skills, and professional attitudes required of the consultant paediatrician.


The future training of consultant paediatricians. Methods of training.


The future training of consultant paediatricians. Programme of training.


The future training of consultant paediatricians. Requirements for training.


Further medical education of Aberdeen graduates 1956-58.


Students' perceptions of medical school and their attitudes towards patients.


The teaching of anatomy in the Wessex hospital region.


An evaluation of programmed instruction in a new medical faculty.


The effects of septal, thalamic, and tegmental lesions on general activity in the hooded rat.


An evaluation of self-pacing in an auditory identification learning task.


The effect of parental age on the rate of female maturation.


Influence of age on rat liver and kidney chromatin.


The sulphokinase, arylsulphatase-B and acid phosphatase activities of carrageenin granuloma in rats of different ages.


The role of the thyroid and food intake in the ageing of collagen fibres. II. In the old rat.


Ultrastructure of chromosomes of L-cells at metaphase.


Cytotoxic and cancerostatic effects of isothiocyanates and related compounds. IV. Benzhydryl- and cinamoylisothiocyanates.


Substances with antineoplastic effect. XL. The influence of sodium salt of beta-4-methoxybenzoyl-beta-bromacrylic acid (MBBA) and some related substances on the respiration of rat liver homogenate and Yoshida ascites rat sarcoma cells; the influence of these substances on the mechanisms of oxidative phosphorylation of the liver homogenate.


In vivo testing of cytostatics. A contribution to selective chemotherapy.


The tumour-inhibiting effect of properdin.


Resistance and susceptibility to tumours. 3. Effect of some derivatives from immunized animals on the Bo4 and Ehrlich carcinomas.


Isoenzymes of lactate dehydrogenase in human lung tissue and in malignant lung tumours.


Immune response and pyrrole levels in rat sera after a single injection of methionine sulphoximine as compared with the effect of whole body irradiation with x-rays.


Sterile reflux: report of 24 cases.

Sterile reflux: report of 24 cases.


Localization of phosphaturic action in the nephron of patients with primary hyperparathyroidism.


Vertebral epiphyseodesis of the thoracic curve in the operative treatment of idiopathic scoliosis.


On abortion, a dissent.

On abortion, a dissent.


The village medical aides--Alaska's unsung, unlicensed and unprotected physicians.


The Environmental Health Program of the Alaska Area Native Health Service.


Fluoridation for Seward.

Fluoridation for Seward.


The education and care of pilots.

The education and care of pilots.


Pain in the upper extremities.

Pain in the upper extremities.


Microscopy of the living pancreas in situ.


Fine structure of the human menstrual corpus luteum at its stage of maximum secretory activity.


The ultrastructure of stellate cells in the pars distalis of the salamander pituitary gland.


Ultrastructural properties of primary olfactory neurons in fish (Lota lota L.).


The ultrastructure of the stellate cell in the rabbit pars distalis.


Features of trigeminal mesencephalic nucleus structure and organization. I. Light microscopy.


Renewal of Paneth cells in the small intestine of the mouse.


The resistance to airflow caused by heat and moisture exchanger and by artificial airways.


Disseminate and recurrent infundibulo-folliculitis. Report of a second case.


S.C. Paul Lecture. Pulmonary abscess in Ceylon.


Extradural haematoma.

Extradural haematoma.


Conference on community medicine and medical cooperation in Asia and Oceania.


Polyneuropathy following acute arsenic poisoning.


Spontaneous mediastinal emphysema: Hamman's syndrome. A report of two cases and review of literature.


A case of pheochromocytoma with polycythaemia successfully treated surgically.


Post-partum hypopituitarism--Sheehan's syndrome.


The effect of local heating on blood flow through the testes of some Australian marsupials.


Clinical usefulness of adrenal phlebography.


Angiography in the diagnosis of liver disease.


Hypotonic duodenography for improved radiologic evaluation of pancreaticoduodenal disease.


X-ray of the month. Section of chest diseases.


Percutaneous transhepatic cholangiography.


Electrocardiogram of the month: fatigue and syncope.


SEDAC as a replacement for electroconvulsive therapy; a preliminary report.


Patterns of psychological decompensation in patients with spinal cord syndromes.


Lithium carbonate treatment during pregnancy; report of a case.


Treatment considerations in the adolescent inpatient; report on ninety-two cases compared with ninety-two adults.


The mono-amine oxidase inhibitors; their usefulness and their safety.


Presidential address.

Presidential address.


Surgical training in East Africa.

Surgical training in East Africa.


Empyema thoracis.

Empyema thoracis.


Goitre in Kenya.

Goitre in Kenya.


Skelecasts--a concept of lightweight immobilisation; preliminary communication.


An analysis of 100 cases of tuberculosis of the spine in Nairobi, Kenya.


Septic abortion.

Septic abortion.


Unusual subcutaneous swellings in African patients.


The changing role of central service.

The changing role of central service.


The health professionals: cure or cause of the health crisis?


How hospitals can meet 'disclosure' requirements.


Community workers serve as link between hospital, ghetto residents.


Four hospitals join in planning city-wide disaster alert.


Can the voluntary hospital survive?

Can the voluntary hospital survive?


Reorganizing hospital disaster plan to facilitate reference, revision.


High-school students participate in realistic community drill.


The personnel administrator as a hospital manager.


Communicating with the inner city on health-care problems.


Heliport at your hospital?

Heliport at your hospital?


Housekeeping has important role in disaster planning.


Transference birth fantasies and narcissism.


Transference, somatization, and symbiotic need.


Sensory irruptions and mental organization.


On the nature of addiction to cigarettes.


Further comments on a common type of marital incompatibility.


Defensive reactions to infantile separation anxiety.


The reversal of déjá raconté.

The reversal of déjá raconté.


Some early manifestations of transference. Their implications for the first phase of psychoanalysis.


The metabolic availability of phenol analogues in bacterium NCIB 8250.


Physiological and morphological characteristics of Kurthia zopfii isolated from meat products.


Serological response produced in chickens by three strains of Mycoplasma gallisepticum.


United States Biological Stain Commission; certification of fluorescein isothiocyanate.


Effects of modeling procedures in helping relationships.


Therapist directiveness, client dominance, and therapy resistance.


Temporal correlates of the achievement value and manifest anxiety.


Different psychological effects of lateralized brain damage.


Self-care unit: some lessons in institutional power.


Conditioning and transfer of affective self-references in a role-played counseling interview.


Locus of control in psychiatric patients.


Study of psychological content in the communications of suicidal individuals.


Direction of affective influence in psychotherapy.


Prediction enhancement through the use of moderator variables.


Sex differences and variations in body attitudes.


Field independence and educational-vocational interests.


Impact of audio-visual feedback on group psychotherapy.


Influence of oxygen on maltose metabolism by Mucor rouxii.


Sedative neurosurgery. A contribution to the behavioural sciences.


Paper electrophoretic study of serum proteins after B.C.G. vaccination.


A study of 232 cases of brucellosis in Karnal.


Treatment of muscular dystrophy with laevadosin.


Observations on some hepatic disorders.

Observations on some hepatic disorders.


Hysteria. A review for the general practitioner.


Surgery in camps.

Surgery in camps.


The reaction of the Pacific oyster, Crassostrea gigas, to homologous tissue implants.


Multiple intussusceptions.

Multiple intussusceptions.


Biochemical studies on the multiplication of a nuclear-polyhedrosis virus in the silkworm, Bombyx mori. II. Protein synthesis in larval tissues after infection.


Biochemical studies on the multiplication of a nuclear-polyhedrosis virus in the silkworm, Bombyx mori. 3. Functional changes in infected cells, with reference to the synthesis of nucleic acids and proteins.


The effect of ultraviolet radiation of known wavelengths on a granulosis virus of Pieris brassicae.


Cross infection studies with Heliothis zea using nuclear-polyhedrosis viruses from Trichoplusia ni.


Mode of action of Bacillus thuringiensis toxic crystals in larvae of the silkworm, Bombyx mori.


Symbiontic interrelationships between microbes and ambrosia beetles IV. Ambrosial fungi associated with Xyloterinus politus.


Mitoses in cell cultures from cardiac tissue of the surf clam Spisula solidissima.


Lack of a bactericidal response in the earthworm Lumbricus terrestris after immunization with bacterial antigens.


Bacillus larvae isolation, culturing, and vegetative thermal death point.


Hemolymph proteins of the cabbage armyworm, Mamestra brassicae, after infection with a nucleopolyhedrosis virus.


Influence of a virus infection (densonucleosis) on the formation of uric acid in the fat body of Calleria mellonella.


Toxicity of Bacillus thuringiensis for larvae of the clothes moth, Tineola bisselliella.


Mental disease in employed persons.

Mental disease in employed persons.


Automated multiphasic health screening. A conceptual model and description of a program.


Preventive industrial psychiatry.

Preventive industrial psychiatry.


Return to work. Industry's responsibility.


The industrial medical department laboratory. Experience with automation.


Liability in refusal of tetanus toxoid booster injection.


Gas chromatographic analysis of estrogens. II. Application of estrogen heptafluorobutyrates on to the column by wet or dry sampling through a septumless port.


Studies on the biosynthesis of TMV. II. On the RNA synthesis of infected cells.


The influence of heterochromatin, inversion-heterozygosity and somatic pairing on x-ray induced mitotic recombination in Drosophila melanogaster.


Evaluation of radium-226 in total diet samples, 1964 to June 1967.


Strontium-90 in tri-city diets, August-December 1968.


Radioactivity in California waters, January-June 1968.


Alpha radioactivity in Colorado uranium mines 1961-1968.


Strontium-90 in human bone, October-December 1968.


Environmental levels of radioactivity at Atomic Energy Commission Installations.


Reflections of a clergyman on patient-pastor interaction.


Rubella vaccine recommendations.

Rubella vaccine recommendations.


Therapeutic problems with psychotropic drugs: some epidemiological considerations.


Reactions to local anesthetics.

Reactions to local anesthetics.


Considerations on synovial ragocytosis.

Considerations on synovial ragocytosis.


Electromyography in patients with lesions of the central motor neuron and the so-called parietal muscular atrophy.


Scurvy in children. A report of three cases.


An abortive from of Parkinson's disease?


Schizophrenia and pink spot.

Schizophrenia and pink spot.


Some cardiac effects of diphenylhydantoin.


Short term reaction of biliary bile acids to cholestyramine medication.


Exposure to fibers in the manufacture of fibrous glass.


Combustible gas indicator response in low oxygen atmospheres.


The inhalation toxicity of pyrolysis products of bromochloromethane (CH2BrCl) and bromotrifluoromethane (CBrF3).


Noise control for electric motors.

Noise control for electric motors.


A rapid and sensitive method for estimating carbon monoxide in blood and its application in problem areas.


Evaluation of laser hazards to the eye and the skin.


Anesthesia for endoscopy.

Anesthesia for endoscopy.


Patterns of hair cell damage after intense auditory stimulation.


Noise control of emergency power generating equipment.


Community noise problems--origin and control.


A gas chromatographic determination of benzo(a)pyrene using electron capture.


Microrespirometry of the membranous cochlea and ototoxicity in vitro.


High-speed photography of the larynx in a clinical setting.


Functional aphonia.

Functional aphonia.


Miniature air samplers for sulfur dioxide.


A reappraisal of the innervation of the canine cricothyroid muscle.


Extreme development of the paranasal sinuses. Report of a case.


Endobronchial lipoma. A review of the literature and report of an unusual case.


An evaluation of certain direct reading devices for the determination of ozone.


Experience with burned lead-in plastic material.


Microdetermination of toluenediisocyanate using toluenediamine as the primary standard.


Tear-away sleeve.

Tear-away sleeve.


Launch conditions produced by the titan III-C launch vehicle.


The location of personal sampler filter filter heads.


Ewing's sarcoma of the maxilla.

Ewing's sarcoma of the maxilla.


Barium plus hydrogenated hydrocarbons may explode.


Plugging of vascular canals in the otic capsule.


Antiviral effect of cyclic amines on a 1969 isolate of A2 influenza. Cyclooctylamine and amantadine inhibit the growth of 1969 isolates of A(2) influenza virus to a significant degree. There was slightly more inhibition of the virus by the cyclooctylamine (COA) than the amantadine; however, the dose of COA used was greater than the dose of amantadine. There was no significant difference between flasks treated 3 or 4 hr and those treated 2 hr. However, there was a curious relationship of more plaques in the flasks exposed to the two drugs for the longer intervals. Other experiments done with slight modifications in technique support the antiviral effect demonstrated in this experiment when the cell system is pretreated prior to virus infection. In two experiments, pretreating the cells for 2 hr with COA at 100 mug/ml but removing the drug solution and washing the cells prior to virus inoculation revealed no differences in plaque counts between controls and treated cells. This would indicate that the antiviral effect required the presence of the drug during the early stages of penetration of the cells by the virus particles.


Identification of the Mima-Herellea group of organisms and selected members of the genus Neisseria. To determine a rapid and reliable protocol for the differentiation of Mima polymorpha, M. polymorpha var. oxidans, Herellea, Bacterium antitratum, Neisseria gonorrheae, and other related members of the genus Neisseria, reference cultures were examined on a variety of microbiological media. The media were selected because of the typical morphological and biochemical characteristics exhibited by the test organisms and were those media which would be readily available in a microbiology facility. After compiling data obtained from 21,714 observations, an inclusive protocol is presented which has proven to be quite adequate for the identification of these particular gram-negative bacteria.


Reaction of airborne Rhizobium meliloti to some environmental factors. Survival of Rhizobium meliloti 102F5 in aerosols at 20 C was maximal at high relative humidity (RH) and minimal at low RH. Relatively high concentrations of NO(2), SO(2), or formaldehyde were needed to significantly reduce viability of R. meliloti in aerosols at 50% RH. Except for the reduction in activity of formaldehyde by SO(2), there was no additive or antagonistic effect of mixing pollutants. High environmental RH enhanced bactericidal activity of NO(2) and SO(2). High RH minimized and low RH accentuated the biological effect of ultraviolet light of 300 to 400 nm wavelength.


Biosynthesis of ochratoxin A.

Biosynthesis of ochratoxin A. Biosynthesis of ochratoxin A by Aspergillus ochraceus Wilh. was investigated by radiolabeling experiments in which phenylalanine-1-(14)C and sodium acetate-2-(14)C were supplied to the fungus in sucrose-yeast extract medium. Results showed that phenylalanine was incorporated unaltered into the phenylalanine moiety of ochratoxin A, whereas the isocoumarin moiety of ochratoxin A was mostly derived via acetate condensation.


Effect of repeated irradiation on various characteristics of Salmonella. Four Salmonella serotypes which had been subjected to either 15 or 20 cycles of irradiation and subculture were examined for possible changes induced by the treatment. With three serotypes virulence remained unchanged, and with one serotype a reduction had occurred. A few minor changes in the biochemical characteristics occurred in some instances, but with all cultures the serological property was affected to some extent. Lag times and growth rates of the treated cultures were not altered, but the maximal viable population was usually less than that for untreated cultures.


Some properties of the beta-lactamase genes in Staphylococcus epidermidis. Eighty-three per cent of 200 different freshly isolated cultures of Staphylococcus epidermidis produced beta lactamase. Growth in the presence of acridine orange or ethidium bromide or growth at 44 C resulted in a high frequency of loss of the beta lactamase genes in some strains of S. epidermidis. The relationship between beta-lactamase production and resistance to mercuric, cadmium and arsenate ions differed from that observed in Staphylococcus aureus. It is postulated that the genes for beta lactamase in certain strains of S. epidermidis are on a plasmid.


A simple gas dilution apparatus.

A simple gas dilution apparatus.


Effect of gravity on the colonial morphology of staphylococci in soft agar. After horizontal rotation on a clinostat at 1 rev/min, subsurface colonies of staphylococci in soft agar were compact and spherical; nonrotated colonies were diffuse and elongated.


Prophylactic effects of gamma-aminobutyrylhistidine (homocarnosine) on experimental staphylococcal infections in mice. Prophylactic administration of the dipeptide homocarnosine induced a high degree of resistance to staphylococcal infections in Swiss albino mice. It expressed its antistaphylococcal properties 1 hr after administration, and this protection lasted for at least 1 month. Although 5 mg per animal (approximately 200 to 250 mg/kg) was routinely used in our studies, experiments showed that comparable results could be obtained with 1.5 mg per animal. Rechallenge experiments indicated that an active infection by itself may confer immunity up to 4 weeks, but an infection after treatment with homocarnosine gave complete immunity to reinfection for at least 2 months. Studies in vitro showed that homocarnosine had no effect on the growth or certain other characteristics (ability to ferment mannitol, liquefy gelatin, and to produce coagulase, deoxyribonuclease, and pigment) of S. aureus. It appears that resistance induced by this peptide is an indirect effect mediated by some nonimmunological host reaction. The possible involvement of homocarnosine, among other compounds, in the protective action of deproteinized beef extract against staphylococcal infections is suggested.


Salmonella survey of plant foods used in and around the home. Nine of 100 plant food samples investigated yielded salmonellae. A brilliant green tetrathionate-brilliant green agar combination gave the most salmonellae recoveries.


Antibacterial properties of 3,3',5,5'-tetrachlorotetranitrodiphenylamine. An analogue of tetramethyldicrylamine, 3,3',5,5'-tetrachlorotetranitrodiphenylamine, was synthesized and tested in vitro for its antibacterial activity.


Isolation of phenylalanine-negative Proteus vulgaris. Three phenylalanine-negative Proteus vulgaris strains were isolated from three different sources. The significance of these Proteus strains has not been fully recognized.


Stability of rifampin in dimethylsulfoxide. Stock solutions of rifampin remain stable in dimethylsulfoxide for at least 8 months.


Scanning electron microscopy of selected members of the Streptomyces hygroscopicus group. Distinctive variations in whole spore morphology and spore surface morphology of Streptomyces hygroscopicus strains, which had been observed previously by the authors by the preshadowed carbon replica technique, were confirmed by observations with the scanning electron microscope.


Identification and genetic control of starch-degrading enzymes in maize endosperm.


An improved technique for the separation of glucose 6-phosphate dehydrogenase isoenzymes by disc electrophoresis on polyacrylamide gel.


The nature of thymidine kinase in the human-mouse hybrid cell.


The predominance of heterozygotes found in wild goldfish of Lake Erie at the gene locus for sorbitol dehydrogenase.


Genetic control of alcohol dehydrogenase isozymes in Triticum dicoccum.


Cell population density and phenotypic expression of tissue culture fibroblasts from heterozygotes of Lesch-Nyhan's disease (inosinate pyrophosphorylase deficiency).


Intracerebral mouse protection test for petussis vaccine. II. Immunosuppression with cyclophosphamide.


Preparation and properties of cellulases from rumen microorganisms.


Changes produced in hop extract components by yeasts.


Temperature-sensitive mutation. 3. Temperature-sensitive catalase reaction of a ts-mutant in Paramecium aurelia.


Studies on the taxonomy of the Myxobacterales. I. Record of Canadian isolates and survey of methods.


Inability of cyclophosphamide to inhibit the action of pertussis HSF in mice.


Blood clearance of bacteriophage phi-X 174 in mice: effect of immunosuppressive drugs.


Enhanced resistance to arboviruses of mice with persistent lymphocytic choriomeningitis virus infection.


Influence of temperature upon levels of virus and an induced antiviral principle in tomato plants systemically infected with tobacco mosaic virus.


Surface characteristics of conidia from monosporous cultures of Penicillium digitatum and Aspergillus nidulans var. echinulatus.


The keeping quality of pasteurized egg.

The keeping quality of pasteurized egg.


Determination of the microbiological status of gnotobiotic pigs.


Extended storage of streptococcus lactis in phosphate buffer.


Inactivation of nisin by alpha-chymotrypsin.


The probability of cancer.

The probability of cancer.


Effect of bidrin on the metabolism of dietary components by the bovine.


Medico-legal autopsies. II. Non-traumatic cases.


Epilepsy (a follow-up study of 170 cases).


Carotid cavernous aneurysm. A case report.


Methemoglobinemia due to nitro-aniline intoxication. Review of the literature with a report of 9 cases.


Auricular biopsies in rheumatic mitral stenosis. A histopathologic study of 264 cases.


Railroading method of intramedullary nailing of fractures of tibial shaft. Another method for passing a Kuntschner nail when it fails ordinarily.


Intralobar sequestrated lung. A case report.


Betatherapy with 90Sr in the treatment of pterygium.


Caclium dobesilate in diabetic retinopathy.


Proteins of the normal human aqueous humour.


Malignant melanoma of the choroid in the nevus of Ota.


Calculation of total refractive ocular power and refractive lens power: an ultrasonic-optical procedure.


The mechanism of the lacrimal flow.

The mechanism of the lacrimal flow.


Electromyograms in the early stage of complete paralysis of human extraocular muscles. With special reference to the "fibrillation potential" and "spontaneous discharge".


Ocular manifestations of cystinosis.

Ocular manifestations of cystinosis.


Fluorescein angiography in papilloedema and Pseudo-Papilloedema.


Tolerance of normal and dystrophic hamsters to d-tubocurarine.


Diaphragmatic trauma.

Diaphragmatic trauma.


Gas in the portal venous system.

Gas in the portal venous system.


Acute appendicitis. An analysis of six hundred and sixty-six appendicectomies in adults 1959-1968.


The bowel sounds.

The bowel sounds.


Some medical and engineering considerations of the design of an intra-thoracic artificial heart.


NMR study of conformationally restricted substrates of alpha-chymotrypsin.


Novel lignans from a Cinnamomum sp. from Bougainville.


Photochemistry of 4,5,6,7-tetrahydroindan-2-one.


New syntheses of xanthotoxol and xanthotoxin.


Early detection of bone-marrow injury due to drugs.


Scintillation scanning in a community hospital: A review. 3.


The role of the community hospital in patient care and medical education.


Electrocardiogram of the month.

Electrocardiogram of the month.


Chest X-ray of the month. Section of chest diseases.


Preliminary clinical studies of a new oral antimycotic agent in systemic mycosis.


Hypercalciuria during administration of calcium aminosalicylate as a causitive factor in urolithiasis.


Management training and psychiatry in a company.


Seminars for executives and occupational physicians.


Mental health education for occupational physicians.


Occupational psychiatry and group psychotherapy in Czechoslovakia.


Absenteeism: an unsolved problem.

Absenteeism: an unsolved problem.


Accidents.

Accidents.


Disability.

Disability.


Emotional factors in physical injury.

Emotional factors in physical injury.


The management team approach to industrial plant design. Its influence on mental health.


The epidemiology of mental illness in industry.


Alcoholism and the job.

Alcoholism and the job.


Executive stress.

Executive stress.


A program for alcoholics in a company.

A program for alcoholics in a company.


Psychiatric insurance and industry.

Psychiatric insurance and industry.


Psychiatric disorders and industrial toxicology.


Unions and psychiatric care.

Unions and psychiatric care.


Community-hospital-industrial-rehabilitation-placements: CHIRP.


Rehabilitation and employment of the mentally restored.


Occupational psychiatry. Introduction.

Occupational psychiatry. Introduction.


The medical department and a psychiatric program.


The role of the psychiatrist in industry.


The psychologist and occupational mental health.


The role of the nurse in a mental health program.


A businessman's view of mental health.

A businessman's view of mental health.


Neuropsychiatry in a company.

Neuropsychiatry in a company.


Liver glycogen metabolism in the hyperthyroid rat.


In vitro measurement of resting membrane potentials of thyroid follicles of the albino rat.


Chromatographic studies of aminoacids released in the incubation media of Fasciola hepatica.


Unusual nature of ganglionic slow EPSP studied by a voltage-clamp method.


An extragonadal male antifertility agent.


Effects of some naturally occurring prostaglandins on the isolated hypogastric nerve seminal vesicle preparation of the guinea pig.


Chemical contraction and relaxation of tail tendon collagen after heparin administration in rats of different ages.


Differential uptake of biogenic amines by isolated 5-hydroxytryptamine organelles of blood platelets.


Clearance of amphotericin B-C14 from cerebrospinal fluid.


The evaluation of a new animal method for the prediction of clinical anti-depressant activity.


Feedback suppression of pituitary-adrenal function in rats with pituitary islands.


The chemistry of thiabendazole.

The chemistry of thiabendazole.


Thiabendazole in the treatment of enterobius vermicularis.


Thiabendazole for the treatment of trichinosis in humans.


Treatment of oxyuriasis with thiabendazole.


Thiabendazole and related compounds in treatment of hookworm infestation.


Pinworm infestation. Therapy with thiabendazole.


Community control of intestinal nematodes by thiabendazole treatment.


Treatment of creeping eruption with topical thiabendazole.


Systemic and topical thiabendazole for creeping eruption.


Radiation physics. ORNL-4446.

Radiation physics. ORNL-4446.


Health Physics Division annual progress report for period ending July 31, 1969. ORNL-4446.


Radiation dosimetry research. ORNL-4446.


Radioactive waste disposal. ORNL-4446.

Radioactive waste disposal. ORNL-4446.


Internal dosimetry. ORNL-4446.

Internal dosimetry. ORNL-4446.


Selected serum enzymes as indicators of changes in physical condition. Vol XIX, No 14.


Radiation ecology. ORNL-4446.

Radiation ecology. ORNL-4446.


The effect of 5-fluorouracil on DNA-thymine synthesis in human tumors.


The carcinogenic activity of some 5-nitrofuran derivatives in the rat.


Immunization of C58 mice to line Ib leukemia.


Dependence of immunity to Ib leukemia on an adjuvant effect of immunizing cell preparations.


Immunotherapy and chemotherapy of Moloney sarcoma virus-induced tumors in mice.


The effect of nucleoproteins upon amino acid incorporation into protein in Walker 256 cells.


Suppression of experimental allergic encephalomyelitis by NSC 82196, a new imidazole carboxamide derivative.


Formal discussion: cautionary considerations of combination chemotherapy in the treatment of human malignancies.


An empirical cellular approach to the improvement of cancer chemotherapy.


Improvement of the model systems.

Improvement of the model systems.


The improvement of the animal tumor model.


Induced immunologic response to tumors.

Induced immunologic response to tumors.


Immunologic parameters of host-tumor relationships: spontaneous mammary neoplasia of the inbred mouse as a model.


Immunologic surveillance at the marcoscopic level: nonselective elimination of premalignant skin papillomas.


The use of tumor growth kinetics in planning "curative" chemotherapy of advanced solid tumors.


Cell cycle kinetics and mitotically linked chemotherapy.


The G1--S conversion: a target for cancer chemotherapy.


Variation in selective toxicity: causes and consequences.


Prospects in endocrinology for chemotherapy.


The manipulation of metabolism by drugs and nutrients.


The need for additional alkylating agents.


Utilization of segments of nuclear macromolecules in cancer chemotherapy.


The application of new knowledge to the effective administration of anticancer agents.


Summary of informal discussion on the basis for future approaches to cancer chemotherapy.


New approaches in administration of anticancer drugs.


The present status of cancer chemotherapy--a summary of papers delivered at the Cherry Hill Conference on "a critical evaluation of cancer chemotherapy".


Studies on the biosynthesis of diglycerides and triglycerides in cell free preparations of the fat body of the locust Locusta migratoria.


Renal handling of phosphate in patients with chronic renal failure. The role of variations in serum phosphorus and parathyroid activity.


Hereditary hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency (Mediterranean type).


Inhibition of fat mobilization by propranolol during fasting.


On the mechanism of tension development in glycerinated insect flight muscle.


Influence of ouabain and lack of potassium on QO2 of rat diaphragm in hypertonic sodium chloride solutions.


Acute oliguric intrinsic renal failure. Diagnostic criteria and clinical features in 61 patients.


Hyperglycemia and uric acid.

Hyperglycemia and uric acid.


Recurrent hydronephrosis, retroperitoneal fibrosis and eosinophilia in a patient with previous evidence of Loeffler's infiltrate in the lungs.


Pruritus as a possible early sign of paraproteinemia.


Hereditary deficiency of blood clotting factor VII and Dubin-Johnson syndrome in an Israeli family.


Hemoglobin D Punjab in a Bulgarian Jewish family.


Study on the Mycobacterial polyol dehydrogenases.


Bacteriolytic enzyme produced by Acanthamoeba castellanii.


Nucleo-cytoplasmic studies in the development of influenza virus in mammaliam cells.


Studies on adenovirus type 12 strain variation. I. Cross-neutralization tests.


Action of chloroform on the hemagglutinin of ECHO virus types 7 and 11.


Response of swine to inactivated foot-and-mouth disease vaccine. Duration of immunity and local tissue reaction.


Identification of two plaque variants of Guaroa virus.


Kinetics of the respiratory syncytial virus growth cycle in HeLa cells.


Fiber-associated incomplete and complete hemagglutinins of adenovirus type 6.


Ankylostoma duodenale and ultraviolet irradiation.


Isolation of dengue virus from the blood of a clinical case of encephalitis.


Comparative studies on the protective value of different antigenic preparations from cholera vibrios.


Re-survey for arbovirus antibody in the human sera after an interval of six years.


Virulence of V. cholerae strains, isolated from carriers, in the rabbit ileal loop.


Blood and bone marrow studies in Indian childhood cirrhosis.


Alkaline phosphatase activity in D. M. B. A. induced experimental oral carcinogenesis in hamster cheek pouch.


The anaemia of experimental burns. I. Observations on the nature of anaemia in the immediate post-burn period.


Electrophoretic studies of hamster cheek pouch tissue proteins during progressive experimental oral carcinogenesis induced with D.M.B.A.


The effect of some newer phenothiazine derivatives on certain central nervous system parameters.


Effect of oral contraceptives on the blood coagulation in experimental animals.


Chymous complications in filariasis chylous arthritis. 3. A clinical and lymphographic study.


The effect of methandienone (an anabolic steroid) on nitrogen metabolism following surgical trauma.


Effect of exposure to heat on total blood sulfhydryl (SH) groups in human beings.


A study of sensitivity induced by certain drugs by intradermal skin tests.


Review of byssinosis in India.

Review of byssinosis in India.


Chemical analysis of urinary calculi in Chandigarh area.


Aplastic anemia after hepatitis. A case report.


Congenital deficiency of factor XIII.

Congenital deficiency of factor XIII.


Electro-retino-encephalography in Leber's tapeto-retinal dystrophy.


Sex chromatin and nuclear sex-specific appendages in the newborn.


Mitochondrion-desmosome complexes in human hepatocytes.


Pituitary monoamines of the cat with special reference to the presence of an unidentified monoamine-like substance in the adenohypophysis.


A neurofibrillar body in the perikaryon of nervus terminalis ganglion cells in teleosts.


Peroperative hydration with lactated Ringer's solution versus a saltfree restrictive fluid regimen. Effects on postoperative fluid and electrolyte metabolism and renal function in patients undergoing partial gastrectomy.


Drug interactions in perspective.

Drug interactions in perspective.


Hospital pharmacy service--an administrator's viewpoint.


Career patterns among hospital pharmacists in the Southeastern United States.


Breaking the language barrier with E.D.P.


A flexible drug display system.

A flexible drug display system.


Assay of potassium gluconate solution.

Assay of potassium gluconate solution.


Observations on thyroid carcinoma and its surgical treatment. I. Stage of the tumour at commencement of treatment.


Observations on thyroid carcinoma and its surgical treatment. II. Aetiology and sympatomatology.


Observations on thyroid carcinoma and its surgical treatment. 3. Diagnostic procedures and their evaluation.


Observations on thyroid carcinoma and its surgical treatment. IV. Surgery and its results.


Radiostronium in the early diagnosis of the bone metastases of patients with mammary carcinoma. Comparison of a radiological and isotope study.


Combined 5-fluoro-uracil and procarbazin in the treatment of lung metastases from different carcinomas.


The management of corrosive gastritis.

The management of corrosive gastritis.


Unusual causes of mechanical ileus: obturator hernia and duodeno-jejunal obstruction.


Two unusual cases of metastasis of prostatic cancer: metastases to the spermatic cord and the epididymis.


Haemobilia associated with hepatic necrosis after halothane anaesthesia. A case report.


The action of prostaglandin 15-hydroxydehydrogenase on various prostaglandins.


Arabinonucleotides. I. A study of the formation of 3,-arabinonucleotidyl esters by the conversion of an internucleotide linkage.


Erythrocyte metabolism and function: hexokinase inhibition by 2,3-diphosphogly- cerate and interaction with ATP and Mg2+.


The effect of mersalyl on the oxidation of succinate by housefly mitochondria.


Fluorescence and oxygen evolution from Chlorella pyrenoidosa.


Seleno amino compounds from Astragalus bisculcatus. Isolation and identification of gamma-L-glutamyl-Se-methyl-seleno-L-cysteine and Se-methylseleno-L-cysteine.


Analysis of submaxillary mucins for amide and tryptophan contents.


The assignment of structure to the formamidopyrimidine nucleoside triphosphate precursor of pteridines.


Slow reactions of Ca2+ and Zn2+ with the surfaces of bone powder and anorganic bone.


The effect of myo-inositol on the synthesis of arginase and ornithine transaminase in baker's yeast.


The effects of actinomycin D on the increased total hydroxyprolinuria in healing rachitic rats.


Mechanism of the diabetogenic action of growth hormone. I. Effect of polypeptides derived from growth hormone on glycolysis in muscle.


Mechanism of the diabetogenic action of growth hormone. II. Effect of polypeptides derived from growth hormone on fat metabolism.


The thyroid-stimulating properties of long-acting thyroid stimulator gamma G-globulin subunits.


The steroid induction of glutamine synthetase in chick embryo retinas in culture. A possible role of corticosteroid-binding globulin.


Biosynthesis of streptomycin. VI. Myo-inosose-2, an intermediate in streptidine biosynthesis.


Macromolecular binding of aldosterone in the toad bladder.


Anaplerotic CO2 fixation in mesophilic and thermophilic bacilli.


Gas chromatographic analysis of myo-inositol in microgram samples of brain.


Chemical analysis of the mucopeptide of Mycobacterium smegmatis.


The "hot" thyroid nodule.

The "hot" thyroid nodule.


Transformation of steroids by mixed cultures.


An improved appliance for the pre-surgical orthodontic preparation of the cleft case for secondary bone grafting.


Heat-retaining mattress for temperature control in surgery.


Epidemic malaise.

Epidemic malaise.


The influenza epidemic.

The influenza epidemic.


Television for emergency treatment.

Television for emergency treatment.


Cytotoxic lymphocytes in Hodgkin's disease.


Recurrent inguinal hernia with three sacs.


Blood-gas tensions and aerosols.

Blood-gas tensions and aerosols.


Fibrinolysis and toxemia of pregnancy.

Fibrinolysis and toxemia of pregnancy.


Vitamin C activity of D-isoascorbic acid for the guinea pig.


A study of the pathogenesis of rheumatic fever, glomerulonephritis and other autoimmune diseases triggered by infection.


On the mechanism of "rosette" formation in human and experimental thyroiditis.


The actvity of mouse Kupffer cells following intravenous injection of T4 bacteriophage.


The immunogenicity of phagocytosed T4 bacteriophage: cell replacement studies with splenectomized and irradiated mice.


Heterogeneity of populations of antibody-forming cells fractionated by glass bead columns.


Successive blood volume determination with human serum albumin-131-I without increasing uncertainty. A solution of edose- and dosage problems.


Syntheses of some derivatives alpha-hydroxyamino-gamma-hydroxycarboxylic acids.


In vitro and in vivo investigations of a new timed-release dosage form of propoxyphene hydrochloride.


Analysis of the crystall structure of syn-p-nitrobenzaldoxime.


Surface characters of dividing cells. 3. Unequal division caused by steep temperature gradient in grasshopper spermatocyte.


Division and growth of single mesophyll cells isolated enzymatically from tobacco leaves.


Photocontrol of development of excised Eragrostis embryos.


Experimental control of fruit-body formation in Coprinus macrohizus.


Changes in RNA-, DNA- and proteinsynthetic activity during the formation of analfin processes in ethisterone-treated females of Oryzias latipes.


Effects of androstenedione, 19-norethynyltestosterone, progesterone, and medaka, Oryzias latipes.


Effect of thyroxine and pentachlorophenol on the metabolism of 14C labelled substrates in the tissues of the albino rat.


Factors which determine the gastric secretory response to 2-deoxy-D-glucose. The physiological factors which determine the penetration of the brain by 2-deoxy-D-glucose have been studied and the practical importance of the blood-brain barrier has been demonstrated. The evaluation of the gastric secretory response to 2-deoxy-D-glucose has been shown to depend upon the plasma glucose concentration. It is concluded that because of the hazards and uncertainties in the use of 2-deoxy-D-glucose in man its use is to be deprecated.


The effect of diversion of intestinal contents on the progress of Crohn's disease of the large bowel.


Hypothalamus and growth hormone release.


"Therapeutic jungle".

"Therapeutic jungle".


Jejunal transport of electrolytes and water in intestinal diseases. The role of decreased absorption of electrolytes and water by the jejunum in the pathogenesis of diarrhoea was examined in patients with intestinal scleroderma, ileocolitis, gastric hypersecretion, or extensive ileal resection. Absorption of electrolytes and water from a 20-cm segment of jejunum was compared in 10 patients and six healthy volunteers. Malabsorption of electrolytes and water by the jejunum may contribute to diarrhoea in scleroderma, regional enteritis, and gastric hypersecretion. After ileal resection, jejunal absorption was normal.


Klebsiella mutants showing temperature-dependent polysaccharide synthesis.


Ectopia cloacae--a misnomer.

Ectopia cloacae--a misnomer.


Selection for prothrombin time at 18 weeks of age in chickens.


The physician's disclosure to his patient: full or partial?


Virginia medical examiner system statistical data--1968.


Legal aspects of the hospital emergency department.


The anomalous shear lability of SP50 DNA.


Effects of two TMV strains on the synthesis and stability of chloroplast ribosomal RNA in tobacco leaves.


Insertion of phage Mu. 1 within prophage lambda. A new approach for studying the control of the late functions in bacteriophage lambda.


Comparison of the effects of ultraviolet light and ethylmethanesulphonate upon the frequency of mitotic recombination in yeast.


A new class of clear mutants from coliphage 434 hy not complementing CII and C3 mutants for lysogenization.


Postpartum thrombophlebitis of the ovarian vein.


Malabsorption syndrome in Singapore.

Malabsorption syndrome in Singapore.


Influence of morphine on muscle relaxants in anesthetized dogs.


Products most frequently ingested--1968.


Plantain meals and serum 5-hydroxytryptamine in healthy Nigerians.


Interval analysis of heart rhythm.

Interval analysis of heart rhythm.


Duration of the phases of left ventricular mechanical systole in healthy men aged 45 to 64 years.


Aneurysms of the splenic artery in portal hypertension.


Factors affecting early patency of human venous allografts in arterial reconstruction.


Importance of temperature for the diagnosis of sulphonamide crystalluria in man.


Benign tumours of the stomach and duodenum. Clinical and radiological aspects.


Erythema induratum Bazin and lymphographic changes compatible with tuberculosis of the retroperitoneal lymph-nodes.


Carcinomatous changes in lupus vulgaris.


Studies on the cell cycle of Ehrlich carcinoma cells transplanted into allogeneic and xenogeneic hosts.


Variations in thickness of cortical bones in two populations.


Blastic transformation of lymphocytes in mixed cultures in vitro.


Seromucoid fraction in rats bearing Yoshida solid sarcoma.


The influence of fatigue on the osmotic resistance of white blood cells.


Studies on proteolytic activity of blood and the lymphnodal blastic reaction in the course of adjuvant arthritis in rats.


Studies on the use of human kidney tissue cultures for detection of cytotoxic properties of human sera.


Streptomyces olivaceus 142. II. Isolation of the antibiotic and its properties.


Histochemical and biochemical studies on the activity of gamma-glutamyl transpeptidase in the central nervous system of rats anesthetized with halothane and diethyl ether.


Comparative quantitative studies on cholinolytic agents. I. Atropine and methylatropine.


Molecular heterogeneity of human serum albumin.


Comparative studies on the occurrence of lipid A, diaminopimelic acid and arabinose in Nocardia cells.


Production of circulating antibodies and development of delayed hypersensitivity in rabbits infected with Mycobacterium avium.


The role of delayed hypersensitivity and circulating antibodies in rabbits infected with Mycobacterium avium.


Secretion of gamma-glutamyl transpeptidase (GGTP) in experimental cholestasis.


The influence of castration and administration of stilbestrol on the gamma-glutamyl transpeptidase activity in the liver of male rats.


Comparative quantitative studies on cholinolytic drugs. II. The action of scopolamine, methylscopolamine and butylscopolamine.


Aortic valve replacement with a ball-valve prosthesis. Detailed analysis of early and late results.


Carotid artery back pressure: a test of cerebral tolerance to temporary carotid occlusion.


Caval interruption for prevention of pulmonary embolism. Long-term results of a new method.


Aorta to pulmonary artery shunts. Pulmonary vascular changes in newborn calves and their resolution following shunt closure.


Intra-aortic balloon pumping. Hemodynamic and metabolic effects during cardiogenic shock in patients with triple coronary artery obstructive disease.


Phase-shift balloon pumping in medically refractory cardiogenic shock. Results in 27 patients.


Hyperbaric oxygenation: influence on coronary blood flow and oxygen delivery to the myocardium.


Isoproterenol, hemodynamics and acid-base alterations.


Penetrating abdominal vascular injuries.


Distal tibial arterial bypass. Analysis of 91 cases.


Femoral grafts in diabetics. Resulting conservative amputations.


Late failure of arterialized in situ saphenous vein.


Secondary disruption of vascular repair following war wounds.


Arteriographic pitfalls in the diagnosis of renovascular hypertension.


Arrhythmias and left ventricular efficiency following infarction and infarctectomy.


Latent mediastinal tamponade after open-heart surgery.


Irreversible denaturation and "thermal fractionation" as the basis of narrowing of mammalian DNA heterogeneity.


Abolition of the effect of hypovolemia on the thirst threshold after cervical vagosympathectomy in dogs.


The management of compound depressed fractures of the skull.


An analysis of the modes of presentation and treatment of hydatidiform mole.


From Russia--with admiration.

From Russia--with admiration.


The spectrum of erythema multiforme.

The spectrum of erythema multiforme.


Bowen's disease of the breast.

Bowen's disease of the breast.


A case of multiple congenital anomalies--D1 trisomy syndrome.


A case of subacute discoid lupus erythematosus.


Blood levels of nicotine and physiological effects after inhalation of tobacco smoke.


Alk-1-enyl groups of glycerophosphatides from human aortic intima, plasma and erythrocytes.


Behavioural and brain neurohormonal changes produced by acute heat stress in rats: influence of psychopharmacological agents.


The effect of chlordiazepoxide, diazepam and nitrazepam on catecholamine metabolism in regions of the rat brain.


Histamine-containing epithelial cells in rat stomach. A possible storage site for the intrinsic factor.


Alteration of norepinephrine responses in the dog by dual adrenergic blockade.


The effect of a pair of enantiomers with local anesthetic activity on action potential generation and acetylcholine sensitivity in muscle.


Observations on the pharmacological properties of inflammatory exudate.


Stereoisomerism and differential activity in excitation block by local anesthetics.


Effect of reserpine on the uptake of 1,2-3H-testosterone by mouse prostate glands.


Effect of fenfluramine on the d-amphetamine toxicity in mice.


Long-term hepatic tolerance of amiodarone in the clinic.


Effect of stimulation of midbrain raphe on serotonin (5-HT) level and turnover in different areas of rat brain.


Scleral lesions in rheumatoid arthritis.


Erosive arthritis of the metacarpophalangeal joints in rheumatoid arthritis and tuberculosis.


Definite roentgenographic improvement in seronegative polyarthritis.


Polymyalgia rheumatica.

Polymyalgia rheumatica.


A histochemical method for demonstration of a new steroid dehydrogenase in the human ovary (17 alpha-hydroxysteroid dehydrogenase).


Subcutaneous abscess caused by dematiaceous fungus.


Pattern of neoplasia in children--a study of 215 cases.


Mucormycosis of intestine.

Mucormycosis of intestine.


Spectrum of minor histologic alterations in livers obtained from medico-legal autopsies.


Deoxyribonucleic acid homology and relative genome size in Mycoplasma. The deoxyribonucleic acid homologies of Mycoplasma laidlawii type A and type B, M. pulmonis (#47 and #63), and M. hominis were determined by membrane methodology. The homology data revealed a difference in genome size between M. laidlawii type A and type B. This difference also held with stringent conditions of annealing (high temperature). Little or negligible homology was shown to exist between the M. laidlawii strains type A and type B and M. pulmonis strains 47 and 63 and M. hominis. M. hominis showed less than 10% homology to the M. pulmonis and M. laidlawii strains. Neither of the M. laidlawii strains showed more than 2% annealing to the M. pulmonis strains. Reaction rate studies are suggested as a means of demonstrating the phylogenetic relationship between the Mycoplasma and other microorganisms.


Somatic O antigen relationship of Brucella and Vibrio cholerae. The antigenic relationship between Brucella species and Vibrio cholerae was examined by agglutinin and agglutinin-absorption tests by using rabbit antisera. Brucella antisera agglutinated only the Inaba serotype of V. cholerae and at low titer. Inaba-reactive antibody was absorbed by either heat-stable (100 C, 2 hr) Ogawa or Inaba O antigens. Cholera antisera from rabbits immunized with either O or HO antigens of either Ogawa or Inaba serotypes contained brucella agglutinins. This activity was absorbed completely from Ogawa antisera by either Ogawa or Inaba O antigens but only partially from Inaba antisera by Ogawa O antigen. These findings support the claim of Gallut that the cross-reaction is due to heat-stable O antigens of V. cholerae rather than heat-labile flagellar antigens as described in many text books. The cross-reactive component is more dominant in the Inaba than in the Ogawa serotype of V. cholerae.


Differential lytic response of enterococci associated with addition order of lysozyme and anions. Suspensions of Streptococcus faecium, prepared by washing with and resuspending in water, were lysed slowly if sodium chloride was added prior to lysozyme; however, if brief incubation with lysozyme was followed by addition of sodium chloride, lysis was immediate and extensive. Relatively lysozyme-resistant strains of S. faecalis could be lysed readily by adding lysozyme first. The primary addition of lysozyme apparently resulted in a "sensitized" cell with a damaged wall, as evidenced by N-acetylhexosamine release. Anionic detergents could replace sodium chloride in lysing these sensitized cells. The difference in activity associated with the order of addition probably involved a competition for reactive sites on the cell surface.


Progressive changes of Vibrio serotypes in germ-free mice infected with Vibrio cholerae. Germ-free mice inoculated with Vibrio cholerae became colonized with vibrios throughout the gastrointestinal tract, but they did not become ill. High vibrio concentrations in the feces were observed throughout the 3 months of observation in spite of the presence of serum antibody. Reciprocal conversions of both Inaba and Ogawa serotypes occurred regularly after inoculation and could be correlated temporally with the appearance of serum-agglutinating antibody. Both of these smooth serotype were later progressively replaced by rough vibrios. Rough to smooth serotype reversions were also found in mice inoculated with a rough vibrio strain. Studies employing immunosuppression and selective vaccination suggested that such serotypic changes were a result of the selective effect of antibody within the intestinal lumen.


Genetic homologies among Streptomyces violaceoruber strains. Most of the genetic studies on streptomycetes have been done with cultures erroneously designated as Streptomyces coelicolor. To determine whether these cultures are genetically homologous with the S. violaceoruber nominifer, their deoxyribonucleic acids (DNA) were analyzed, and selected pairs of mutants were crossed. The four cultures used in genetic studies, and called S. coelicolor in the literature, were found to constitute a genospecies, based upon DNA hybridization and recombination tests. In addition, DNA from Actinopycnidium caeruleum formed extensive duplexes with S. violaceoruber DNA. S. violaceoruber cultures and A. caeruleum were distinctly different from the S. coelicolor nominifer.


Effect of culture medium composition and pH on the production of M protein and proteinase by group A Streptococci. The effects of pH, yeast extract, and neopeptone on the production of extracellular proteinase and M protein by group A streptococci were studied with a type 1 strain capable of producing both M protein and proteinase. The strain DS 2036-66 grew moderately well in a semisynthetic broth. M protein was produced without adding peptides to the medium. When added to a medium with 1% glucose, yeast extract (0.1%) was found to stimulate both growth and proteinase formation. Limiting the glucose to 0.25% prevented a drop in pH below 6.7 and prevented proteinase formation. Although less growth occurred with limited glucose, M protein of high specific activity was produced with an actual increase in acid-extractable M protein during the stationary phase of growth. When the medium was buffered at pH 7.85 with tris(hydroxymethyl)aminomethane buffer, 0.5% neopeptone prevented proteinase formation. This was true even in the presence of 1% glucose and 0.1% yeast extract, which resulted in a fall in pH to about 4.8 by 48 hr. Growth was greater than in Todd Hewitt broth, but the specific activity of M protein was considerably less than that found in the medium with glucose limited to 0.25%. Neopeptone was found to have little direct action on crude streptococcal proteinase. Instead, the evidence suggested that neopeptone somehow prevents proteinase elaboration. Yeast extract, on the other hand, appears to stimulate proteinase elaboration. To prevent proteinase formation, neopeptone must be added early, during the logarithmic phase of growth or at the start. In contrast, when yeast extract was added as late as 24 hr, it resulted in the elaboration of extracellular proteinase and in the decline of M protein. When 38 M nontypable strains from the diagnostic laboratory were tested for proteinase activity under conditions similar to those used in the diagnostic laboratory, only six produced much proteinase.


Dissimilation of methionine by a demethiolase of Aspergillus species. Enzyme preparations obtained from the mycelium of Aspergillus species broke down methionine by co-dissimilation. The deaminase and demethiolase activities of crude extracts were increased 100-fold by precipitation with (NH(4))(2)SO(4) and column chromatography on diethylaminoethyl cellulose. The enzyme acted on d-methionine but not on l-methionine. The enzyme was labile: it was inactivated by oxygen and ascorbic acid but ethylenediaminetetraacetic acid and mercaptoethanol preserved its activity. Enzyme activity decreased even at 4 and -30 C and was lost rapidly above 45 C. It was most rapid at 35 C and at pH 8.0 to 9.0. For the following reasons, it was concluded that deamination and demethiolation of methionine were effected by the same enzyme: both activities increased equally at each stage of purification; ammonia, methanethiol, and alpha-keto butyric acid were formed in amounts equivalent to the amount of methionine dissimilated; the K(m) and optimal pH for formation of both keto acid and methanethiol were the same; both activities remained in the same fractions that were separated by electrophoresis and the activities were equivalent. The purified enzyme demethiolated alpha-keto methionine and alpha-hydroxy methionine and split the sulfur linkage of ethionine but did not cleave cystathionine. Few amino acids were deaminated. The enzyme was sensitive to some carbonyl and sulfhydryl reagents and was relatively insensitive to heavy metals other than Hg(++). The K(m) was 1.3 x 10(-3) to 1.5 x 10(-3)m at pH 7.0. No requirement for cofactors was noted, and attempts to dissociate the enzyme, including dialysis with hydroxylamine, were unsuccessful.


Temperature-sensitive yeast mutant defective in ribonucleic acid production. A single, recessive mutation in a nuclear gene confers a temperature-sensitive growth response in a mutant of Saccharomyces cerevisiae, ts(-) 136. The mutant grows normally at 23 C, but exhibits a rapid and preferential inhibition of ribonucleic acid (RNA) accumulation after a shift to 36 C, demonstrating a defect in stable RNA production. Cultures of the mutant which were shifted from 23 to 36 C display the following phenomena which indicate that messenger RNA (mRNA), as well as stable RNA production, is defective. The entrance of pulse-labeled RNA into cytoplasmic polyribosomes is even more strongly inhibited than is net RNA accumulation. The rate of protein synthesis, at first unaffected, decreases slowly; this decrease is paralleled by the decay of polyribosomes to monoribosomes with a half-time of 23 min. The polyribosomes which remain after a 30-min preincubation of the mutant at 36 C are active in polypeptide synthesis in vivo, whereas the monoribosomes which accumulate are not. Furthermore, ribosomes isolated from a culture of the mutant preincubated for 1 hr at 36 C are inactive in polypeptide synthesis in vitro, but can be restored to full activity by the addition of polyuridylic acid as mRNA. We conclude that mutant ts(-) 136 is defective either in the synthesis of all types of cytoplasmic RNA, or in the transport of newly synthesized RNA from the nucleus to the cytoplasm, and that the mRNA of a eucaryotic organism (yeast) is metabolically unstable, having a half-life of approximately 23 min at 36 C.


Ultrastructure of putrefactive anaerobe 3679h during sporulation. Sporulation of putrefactive anaerobe 3679h was studied by observation of ultra-thin sections in the electron microscope. The customary stages were observed during forespore formation, spore maturation, and liberation of the free spore. The exosporium was partially laminated and devoid of the hairlike surface projections observed on spores of some species. Atypical membrane configurations occurred in some cells, and, occasionally, cells with bipolar forespores were found.


Cation-activated nucleotidase in cell envelopes of a marine bacterium. Isolated cell envelopes of a marine bacterium, M.B.3, have been prepared which possess a nonspecific, cation-activated nucleotidase. The cell envelope comprises approximately 35% (dry weight) of the whole cell and contains protein, 60.2%; lipids, 20.7%; hexose, 3.4%; and ribonucleic acid, 4.6%. No deoxyribonucleic acid could be detected in the preparations. The nucleotidase has an essential requirement for Mg(2+); maximum activation at pH 8.0 occurs at a divalent cation concentration of approximately 80 mm. At a Mg(2+) to adenosine 5'-triphosphate (ATP) ratio of 2:1, the enzyme was further stimulated by monovalent cations Na(+), K(+), NH(4) (+), and Li(+). Maximum activity was found at a monovalent ion concentration of approximately 0.3 m. The envelope preparation liberated inorganic orthophosphate (P(i)) from ATP, adenosine 5'-diphosphate (ADP), and adenosine 5'-monophosphate (AMP) at similar rates. Thin-layer and ion-exchange chromatography show that when AMP, ADP, and ATP were utilized as substrate, approximately 1, 2, and 3 moles of P(i), respectively, were produced per mole of adenosine. P(i) was also liberated from the 5'-triphosphates of guanosine, uridine, and cytidine. The enzyme preparation did not attack p-nitrophenyl phosphate, beta-glycerophosphate, or inorganic pyrophosphate. Sulfhydryl inhibitors p-chloromercuribenzoate, N-ethyl maleimide, and iodoacetate had little effect upon the nucleotidase activity. Ca(2+) and ethylenediaminetetraacetic acid caused complete inhibition of the system, whereas ouabain had no effect upon the enzyme activity. The concentrations of Na(+) (0.3 m) and Mg(2+) ions (60 to 80 mm) required for maximum ATP-hydrolyzing activity were similar to those concentrations necessary for maintenance of cell integrity and for the prevention of cell lysis.


Comparison of the pathogenicity for mice of Mycobacterium fortuitum and Mycobacterium abscessus. The pathogenicity for mice of 12 strains of Mycobacterium abscessus was compared with that for 8 strains of M. fortuitum. Both species caused lesions in kidneys and produced "spinning disease" resulting from inner ear infections. No major differences in pathogenicity of these two species were demonstrated. Strain to strain variation was marked, especially with M. abscessus. For example, 1.6 x 10(6) organisms of strain 11188 of M. abscessus produced death in four of five animals within 42 days, whereas strain 380 of M. abscessus failed to produce any deaths within 42 days. In the case of M. fortuitum, the greatest mortality observed was one of five animals, yet the incidence of spinning disease and kidney disease occurred earlier postinfection than in mice infected with M. abscessus. Histologically, abscess formation by a strain of M. abscessus was greater than by a strain of M. fortuitum, but this difference cannot be interpreted as a species difference.


Cell wall residues in yeast protoplast preparations. Protoplast preparations made from Saccharomyces cerevisiae by prolonged treatment with snail digestive juice contained fibrils and chitinous bud-scar residues from the original cell wall.


Fine structure of fruiting bodies of Stigmatella aurantiaca (Myxobacterales). The fruiting body of Stigmatella aurantiaca consists of a thick stalk supporting a number of individual cysts. The stalk is made of discontinuous tubules, of dimensions known for vegetative cells, which are oriented parallel to the longitudinal axis of the stalk. The red-brown cysts contain numerous, randomly oriented myxospores which are surrounded by thick, fibrous capsules. Their cell walls are wavy or ruffled and exhibit fewer budlike infoldings than reported for myxospores induced in liquid. We suggest that the extended time period available for metabolic and regulatory adjustments by the cell during morphogenesis within cysts accounts for the presence of considerably fewer deep cell wall infoldings than in glycerol-induced myxospores.


Oxidation of ammonia by spheroplasts of Nitrosomonas europaea. The ammonia-oxidizing activity of Nitrosomonas europaea spheroplasts was restored by addition of hydroxylamine or by preincubation with Mg(2+).


Estradiol-induced wasting syndrome in conventionally reared and germ-free mice. The pathogenesis of the estradiol-induced wasting syndrome is complex and cannot be explained solely by immunological impairment and subsequent infection.


Serine biosynthesis in Desulfovibrio desulfuricans. Cell-free extracts of Desulfovibrio desulfuricans possess enzymes which catalyze the synthesis of serine from 3-phosphoglycerate via the intermediates phosphohydroxypyruvate and phosphoserine.


Adenosine triphosphate inhibition of yeast trehalase. Yeast trehalase has been found to be inhibited non-competitively by adenosine triphosphate. Such a biological control could explain the accumulation of trehalose during the stationary phase of the growth curve.


Evidence for a reductive pathway for the anaerobic metabolism of benzoate. Evidence is presented for a reductive pathway for the anaerobic metabolism of benzoate by Rhodopseudomonas palustris.


Metabolism of 1-14C palmitic acid in goats in various metabolic states.


Components of bull semen responsible for tonicity-induced turbidity changes.


Energy and protein requirements of the calf.


Energetics of growth of Azotobacter vinelandii in a glucose-limited chemostat culture.


Physiological ecology of Leucothrix mucor.


The stability and cell content of penicillinase messenger RNA in Bacillus licheniformis.


The action of streptomycins on the chloroplast system of Euglena gracilis.


The regulation of some enzymes involved in ammonia assimilation by Rhizobium japonicum.


Lysosomal activity and its control in encysting Hartmannella castellanii.


Potassium transport in non-growing mycelium of Neocosmospora vasinfecta.


Transformation of Micrococcus lysodeikticus by various members of the family micrococcaceae.


Enhancement of melanoma cell culture growth rate by ruby laser radiation.


Conversion of pregnenolone to progesterone by human endometrium in vitro.


Food intake: regulation by plasma amino acid pattern.


Lactate dehydrogenase isozymes in human and rat fetal liver and lung.


Fatty acid metabolism in dystrophic muscle in vitro.


The effect of ouabain on mitochondrial calcium, in vitro.


Effects of cholinergic stimulation or blockade of the rat hypothalamus on discrete-trial conflict behavior.


Anxiety and plasma free fatty acids (FFA).


Time estimation related to personality, cognitive speed and schizophrenia.


Energy metabolism and synaptosomal protein synthesis.


Species and sex differences in electron transport systems in liver microsomes and their relationship to ethylmorphine demethylation.


A simple and rapid fluorimetric determination of catechol-o-methyl transferase (COMT) activity.


Lipid-protein relationships in normal and degenerating myelin.


Proteolytic enzymes in myelin breakdown.


Histochemical demonstration of phospholipids in the nervous tissue.


Comparative studies on phospholipids in morphologically different areas of the brain.


The lipid composition of pure myelin in some demyelinating disorders.


The biochemistry of myelinogenesis.

The biochemistry of myelinogenesis.


Inborn errors of metabolism as a cause of demyelinating disease.


The influence of growth retardation on myelination.


Cerebral vascular permeability in experimental allergic encephalomyelitis.


The gamma-aminobutyric acid (GABA) system of the cerebral white matter and of brain tumours.


Glutamic acid metabolism in the white and grey matter of the brain under normal conditions and under the influence of certain factors.


Biochemical studies in EAE.

Biochemical studies in EAE.


On the biosynthesis of phospholipids and other phosphodiesters via cytidine mechanism.


Functional changes of the RNA content in cellular components of the spinal cord.


Investigation on the macromolecular structure of brain DNA in irradiated animals.


Management of the nephrotic syndrome in children.


Place of paediatric education in the medical curriculum.


Desirable development and measures of improvement of paediatric education in Indonesia.


Some physiological and biochemical patterns in normal newborn infants in Djakarta. II. The normal blood glucose concentration in the first days of life.


Appendicitis in infancy.

Appendicitis in infancy.


Variations in blood LH activity as a function of time in rabbit ovulation.


Metabolic studies on experimental nephrosis. 3. Studies on phosphate metabolism in aminonucleoside nephrosis.


Seasonal fluctuation of the butanol-extractable iodine level in human serum.


Some observations on the fibronolytic activity of blood corporeal elements and vessel walls.


Some properties of scopolaminesterase.

Some properties of scopolaminesterase.


Copper-induced pseudopregnancy in the rat.


The characteristics of the population of soil diphtheroids.


The distribution on MAK columns of RNA isolated from metabolically different yeast strains.


Effect of pH and temperature on the content of corrinoids released from Propionibacterium shermanii.


The effect of herbicides on soil microflora. IV. The action of herbicides on soil microorganisms.


Degradation of some cationic detergents by Pseudomonas pictorum.


The effect of herbicides on soil microflora. I. The effect on the number of soil microorganisms in a field experiment.


The effect of herbicides on soil microflora. 3. The effect of herbicides on ammonification and nitrification in the soil.


Word associations in schizophrenics: a ten-year follow up.


The significance of variations in breathing behaviour in speech and at rest.


Dreams of subjects with bilateral hippocampal lesions.


Folic acid concentrations in psychiatric patients.


Photic arousal response in depressed patients during ECT.


Roentgenologic determination of calcium concentration of skeletal bone with double-beam apparatus.


Resorption of postoperative pneumoperitoneum in children.


Effect of secretin in celiac and superior mesenteric angiography.


Laryngeal function in laryngocele.

Laryngeal function in laryngocele.


Computer-assisted analysis of radiographic neck lesions in chronic rheumatoid arthritis.


Microvascular effects of topically applied contrast media.


Salmonella in wastes produced at commercial poultry farms. Composite samples of freshly voided excreta from 91 poultry houses were tested qualitatively for Salmonella; 26 (29%) were positive. The houses were located on 36 farms, 18 of which (50%) yielded one or more positive samples. In a separate, quantitative study, Salmonella densities ranged from less than 1 to over 34,000 per g of excreta (dry weight). High densities were noted in waste from cage houses, but not in waste from floor houses (litter or wire floors). Salmonella-shedding chickens were located in only one small area of the row of cages examined in detail. A total of 15 Salmonella serotypes were identified during the study.


Oxygen sensitivity of various anaerobic bacteria. Anaerobes differ in their sensitivity to oxygen, as two patterns were recognizable in the organisms included in this study. Strict anaerobes were species incapable of agar surface growth at pO(2) levels greater than 0.5%. Species that were found to be strict anaerobes were Treponema macrodentium, Treponema denticola, Treponema oralis n. sp., Clostridium haemolyticum, Selenomonas ruminatium, Butyrivibrio fibrisolvens, Succinivibrio dextrinosolvens, and Lachnospira multiparus. Moderate anaerobes would include those species capable of growth in the presence of oxygen levels as high as 2 to 8%. The moderate anaerobes could be exposed to room atmosphere for 60 to 90 min without appreciable loss of viability. Species considered as moderate anaerobes were Bacteroides fragilis, B. melaninogenicus, B. oralis, Fusobacteria nucleatum, Clostridium novyi type A, and Peptostreptococcus elsdenii. The recognition of at least two general types of anaerobes would seem to have practical import in regard to the primary isolation of anaerobes from source material.


Congo red-agar plating medium for detecting pigmentation in Pasteurella pestis. Ability to detect pigmented and nonpigmented Pasteurella pestis is essential in plague research, and is currently dependent on use of the synthetic hemin-agar of Jackson and Burrows. We have devised a new differential medium for this purpose, containing Congo red dye and common, commercially available laboratory media. The ease and simplicity of preparation make the Congo red-agar a practical routine laboratory tool in plague research. These findings, possibly indicating a common binding site for hematin and Congo red, should be useful in efforts to determine the chemical nature of a bacterial component associated with high virulence in P. pestis.


Rapid determination of Salmonella in samples of egg noodles, cake mixes, and candies. A glass apparatus system was compared with a standard enrichment broth-selective agar method to test samples of egg noodles, cake mixes, and candy for the presence or absence of salmonellae. The glass apparatus system used fermentation of mannitol, production of H(2)S, or motility, in conjunction with a serological test of flagellar antigens, to detect salmonellae. No salmonellae were detected in 173 samples of food products. Of these samples, 171 were found to be Salmonella-negative after 48 hr with the glass apparatus system. After 72 hr, the standard Salmonella procedure yielded 38 samples which produced Salmonella false-positive results on selective agars. Inoculation of samples with cultures of Salmonella showed that approximately one inoculated cell could be detected after 48 hr of incubation with the glass apparatus. The standard Salmonella test requires a minimum of 72 hr for completion. Compared with the standard Salmonella test, the glass apparatus system is a more rapid and simple system that can be used to determine the presence or absence of Salmonella in these food products.


Incidence of infectious drug resistance among lactose-fermenting bacteria isolated from raw and treated sewage. Raw and treated sewage samples were examined for antibiotic-resistant, lactose-fermenting bacteria. Approximately 1% of the total lactose-fermenting bacteria were multiply resistant. Of these organisms, 50% were capable of transferring all or part of their resistance to a drug-sensitive recipient. Only 43% of those isolated on media containing a single antibiotic were capable of resistance transfer, whereas 57% of those recovered on multiple antibiotic plates transferred resistance. R factors conferring resistance to chloramphenicol, streptomycin, and tetracycline; streptomycin and tetracycline; and ampicillin, streptomycin, and tetracycline accounted for 22, 19, and 15%, respectively, of those identified. The data indicate a significant level of infectious drug resistance among the intestinal bacteria of the urban population.


Country cured ham as a possible source of aflatoxin. Of 10 fungi isolated from a heavily molded country cured ham, 4 were identified as toxigenic strains of Aspergillus flavus.


Inactivation of reovirus type 2 by a combination of chloroform and moderate temperature. The infectivity and hemagglutinins of reovirus type 2 were destroyed at 37 C in the presence of chloroform, whereas no effect of chloroform was noted at 0 C.


Evaluation of thallium acetate-citrate medium for isolation of enterococci. Thallous acetate-citrate (TAC) agar, a selective medium for isolating enterococci from frozen foods, was evaluated. Two types of bacteria, micrococci and group N streptococci, were responsible for erroneously high enterococcus counts on TAC agar. Selectivity of the medium was improved by the addition of 0.01% sodium azide.


Some morphological types of bacteriophages in bovine rumen contents. Six morphological types of bacteriophage were found in bovine rumen contents. Minimal total phage count was 5 x 10(7) per ml of rumen fluid.


Relationship of aflatoxicosis to Salmonella gallinarum infections of chickens. Aflatoxicosis and Salmonella gallinarum exert their effects on the body weight and mortality of chickens without any interaction.


Improved growth medium for group A streptococci. The addition of yeast extract and the use of shaking increase cell crop yield of group A streptococci grown in Todd-Hewitt broth 4 to 5 times that normally obtained.


Osteomalacia in ureterosigmoidostomy.

Osteomalacia in ureterosigmoidostomy.


Therapy in trichinosis with observations on the use of thiabendazole.


Oxytocin sensitivity test (OST) for induction of labour.


An evaluation of a test using 14C labelled triglyceride in the diagnosis of steatorrhoea.


The origin of iron chelating factors in gastric juice.


Memory, imprinting, fixation, and trauma. I.


Prescribing patterns of physicians.

Prescribing patterns of physicians.


Social status and incidence of coronary heart disease.


Oxygen therapy in hypoxic chronic bronchitis. Feasibility of nocturnal oxygen supplementation at home after hospital-induced improvement.


Serum proteins and blood vitamins in anemia of the chronically ill. Possible role of protein undernutrition.


Estimating the number of unnecessary deaths from breast cancer.


Economic aspects of multiple sclerosis. I. A method for classification of income of families of different sizes and compositions and its application in a longitudinal study of multiple sclerosis.


Adjustment of long-term survival rates for deaths due to intercurrent disease.


The radioimmunoassay of human growth hormone.


Rehabilitation of the long-term patient. An action research program in milieu therapy.


Induction of pacemaker activity in an infarct by paired entrant impulses.


Intussusception in childhood. (Report on a seven-year experience at the American University of Beirut Hospital).


Gustatory response and preference behavior in alloxan diabetic rats.


Benign myalgic encephalomyelitis in Lebanon.


The incidence of renal colic and calculi in Kuwait. An epidemiological study.


Anaerobic decomposition of protocatechuic acid by cell-free extract of an Aerobacter cloacae mutant.


Transplantation of tumor by blood from tumor-bearing mice.


Temperature dependency of anti-cancer chemotherapeutic effect.


Studies on the metabolism of indoleacetic acid. I. Isolation and characterization of isatinic acid as an intermediate in the catabolism by a Klebsiella strain.


Studies on the metabolism of indoleacetic acid. II. Isolation and characterization of anthranilic acid as an intermediate in the catabolism by the cell-free extract from a Klebsiella strain.


Ozonolysis of indole derivatives.

Ozonolysis of indole derivatives.


Purification and homogeneity of the histidine ammonia-lyase from Pseudomonas fluorescens.


Distrubances of blood coagulation in acute pancreatitis.


Alimentary chylomicronemia in cases of liver cirrhosis.


Neuroleptanalgesia II in recent myocardial infarction.


Surgical treatment of pleural empyema superinfected by Aspergillus.


The relationship between the predicted maximum oxygen uptake (Vo max) and the age of subjects employed in various professions.


An analysis of the causes of deaths related to surgery of the lung.


The value of the lymphocyte transformation test in the diagnosis of sarcoidosis.


Studies on mycobacteriophages. Adsorption of mycobacteriophages on bacillary cells.


Intestinal malabsorption in patients with pulmonary tuberculosis tested by the d-xylose test.


The level of immunoglobulins in healthy children with thymic hyperplasia.


The level of immunoglobulins in sick children with thymic hyperplasia.


The participation of lactic acid in disturbances of the acid-base balance in acute diarrhea in infants.


An attempt at elucidating the harmful effect of diphtheria toxin on the brain (isotopic studies). II. Spread of 131-I-albumin in cat brain damaged by diphtheria toxin.


Enzymatic and histological changes in the liver of rats after experimental adrenalectomy.


Nucleic acids and protein-bound SH groups in liver cells of rats during chronic poisoning with carbon disulfide.


The value of stereoelectroencephalography in the diagnosis and treatment of epilepsy.


Automatic measurements of the distribution of duration of motor unit potentials in electromyographic records.


Clinical studies on the nature of dysthymic epileptic seizures.


Studies on the causes of diagnostic and prognostic difficulties in childhood schizophrenia.


New observations on atropine coma treatment in psychoses.


An attempt at using rat incisor for investigations on drugs inhibiting inflammatory processes in dental pulp.


Effects of early thymectomy on the teeth and parodontium of white rat.


Consolidation disruption and inhibition in classical conditioning.


Photopatch testing.

Photopatch testing.


Anaphylaxis to streptomycin and hyposensitization (parasensitization).


Contact dermatitis from miranols.

Contact dermatitis from miranols.


Clinical aspects of immune deficiency states.


Contact dermatitis from palladium.

Contact dermatitis from palladium.


Persistent insect bites.

Persistent insect bites.


Fibrinolytic activity in human skin.

Fibrinolytic activity in human skin.


Fibrinogen titre, fibrinolysis and platelet stickiness correlated with capillary bleeding or block in the skin.


The advantages of rearward-facing seats during post decompression emergency descent of multi mach-high altitude transport aircraft. ARL-TR-60-15.


Patterns of physiological activity accompanying performance on a perceptual-motor task. AM 69-8.


Binocular fusion time in sleep-deprived subjects. AM 69-1.


Medical factors in U.S. general aviation accidents. AM 69-2.


Consistency of performance change and autonomic response as a function of expressed attitude toward a specific stress situation. AM 69-7.


Elimination of ornithine-carbamoyl-transferase (OCT) activity from the blood stream studied by single injection and constant infusion of OCT rich plasma in dogs.


Microbial production of xylitol from glucose. A microbiological method is described for the production of xylitol, which is used as a sugar substitute for diabetics. A sequential fermentation process yielded 9.0 g of xylitol from 77.5 g of glucose via D-arabitol and D-xylulose. Candida guilliermondii var. soya (ATCC 20216) consumed 5.1 g of D-xylulose and produced 2.8 g of xylitol per 100 ml. Pentitol production from D-xylulose by yeasts was divided into three types: I, yeast-produced xylitol; II, yeast-produced D-arabitol; and III, yeast-produced xylitol and D-arabitol. D-Xylulose, but not glucose, was dissimilated to xylitol by yeasts under aerobic conditions.


Production and properties of galactosidases from Corticium rolfsii. When Corticum rolfsii was grown in a medium containing bran extract under aerobic conditions, it secreted alpha-D-galactosidase and beta-D-galactosidase into the culture fluid. Pectin also stimulated the production of these enzymes, whereas galactose, glucose, and sucrose stimulated their production to a lesser degree. C. rolfsii produced greater amounts of both enzymes than Aspergillus niger. Both galactosidases in the culture medium hydrolyzed alpha- and beta-p-nitrophenyl-D-galactosides as well as lactose, stachyose, melibiose, and raffinose. Both exhibited optimal activity at pH 2 to 4 and were quite stable under acidic conditions. alpha-Galactosidase was separated from beta-galactosidase by column chromatography.


2-hexanone. (Methylbutyl ketone, MBK).

2-hexanone. (Methylbutyl ketone, MBK).


Antimicrobial activity of some N-substituted amides of long-chain fatty acids. Seventy-three N,N-disubstituted amides of long-chain, principally C(18), fatty acids were screened for antimicrobial activity against bacteria, yeasts, and molds. Amides containing an epoxy group exhibit a broad spectrum of antimicrobial activity which is further enhanced by unsaturation. Mono-unsaturation alone does not contribute a broad level of activity to the N,N-disubstituted amides of the C(18) fatty acids.


Production of staphylococcal enterotoxins A, B, and C in various media. The effect of initial pH and of length of incubation time at 37 C in four different growth media on the production of staphylococcal enterotoxins A, B, and C was determined. A starting pH of 6.8 gave higher yields of enterotoxins B and C than either pH 6.0 or 5.3. The production of enterotoxin A was, however, not materially affected by the low initial pH of 5.3. Prolonged incubation (48 to 72 hr) resulted only occasionally in higher yields of enterotoxin. The effect of the media on the amount of enterotoxin produced is considerable. Difco Brain Heart Infusion (BHI) was inferior to either Fisher BHI, 4% NZ Amine (NAK), or 3% NAK plus 3% protein hydrolysate powder at the three initial pH values, regardless of length of incubation time. The slight effect of the low starting pH on the production of enterotoxin A is being further investigated.


Concentration of beryllium from biological samples.


Observation of microorganisms in soil and other natural habitats. A procedure is described for visually observing and following the activities and interactions of bacteria, actinomyctes, fungi, protozoa, nematodes, and plant roots in masses of soil. Specific microscope components and objectives are used, and the numerical apertures are adjusted such that light diffraction colors are produced to allow differentiation of the various biological entities and their habitat materials. Strains or other alterations in the organisms and their habitat are not employed, and time-lapse photography can be used to follow the activities of soil microorganisms and plant roots. As a result of the use of this technique, it is apparent that in situ indigenous soil microorganisms differ from similar organisms grown in the laboratory, but that, under the proper conditions, the state of the organism in either habitat can be altered to match that which occurs in the contrasting habitat.


Microbial transformation of terpenoids. I. Identification of metabolites produced by a pseudomonad from citronellal and citral. A bacterium capable of utilizing citronellal or citral as the sole source of carbon and energy has been isolated from soil by the enrichment culture technique. It metabolizes citronellal to citronellic acid (65%), citronellol (0.6%), dihydrocitronellol (0.6%), menthol (0.75%), and 3,7-dimethyl-1,7-octane diol (1.7%). The metabolites of citral were geranic acid (62%), 6-methyl-5-heptanoic acid (0.5%), 3-methyl-2-butenoic acid (1%), and 1-hydroxy-3, 7-dimethyl-6-octen-2-one (0.75%).


New technique for rapid purification, entrapment, and recovery of enterotoxin A from a liquid chamber by polyacrylamide gel electrophoresis. Electrophoreis of enterotoxin into a middle liquid section of a polyacrylamide gel column enhances recovery for serological assay.


Effect of stable yttrium concentration on the distribution and excretion of inhaled radioyttrium in the rat.


Separation of cell types of Vibrio fetus. Separation of the coccoid form of Vibrio fetus from cultures containing both the coccoid and vibrioid cell types has been accomplished using rate-zonal centrifugation.


Piggy-back microtransfer technique.

Piggy-back microtransfer technique. A new microtransfer technique is described which uses a modified, V-bottom, disposable, 96-cup plastic plate that permits serial dilutions and direct rapid transfer to a recipient micro cell culture plate.


Primary isolation medium for Cryptococcus neoformans. The isolation and identification of Cryptococcus neoformans is improved by use of a potato dextrose medium containing urea-antibiotic supplements and a pH of 3.5.


Use of fast green in agar-diffusion microbiological assays. Microbiological assay plates containing agar stained with fast green and inoculated with test microorganisms could be readily distinguished from unstained seeded agar plates. The boundaries of zones of growth inhibition were more sharply defined in those plates which contained stained agar.


Algal flocculation with synthetic organic polyelectrolytes. The feasibility of removing algae from water and wastewater by chemical flocculation techniques was investigated. Mixed cultures of algae were obtained from both continuous- and batch-fed laboratory reactors. Representative cationic, anionic, and nonionic synthetic organic polyelectrolytes were used as flocculants. Under the experimental conditions, chemically induced algal flocculation occurred with the addition of cationic polyelectrolyte, but not with anionic or nonionic polymers, although attachment of all polyelectrolyte species to the algal surface is shown. The mechanism of chemically induced algal flocculation is interpreted in terms of bridging phenomena between the discrete algal cells and the linearly extended polymer chains, forming a three-dimensional matrix that is capable of subsiding under quiescent conditions. The degree of flocculation is shown to be a direct function of the extent of polymer coverage of the active sites on the algal surface, although to induce flocculation by this method requires that the algal surface charge must concurrently be reduced to a level at which the extended polymers can bridge the minimal distance of separation imposed by electrostatic repulsion. The influence of pH, algal concentration, and algal growth phase on the requisite cationic flocculant dose is also reported.


A modification of the Gelman sequential sampling valve.


Some effects of ultrasound and of temperature on contractions of isolated mammalian skeletal muscle.


Production of nucleic acid-related substances by fermentative processes. 28. Accumulation of 5' inosinic acid by a manganese-insensitive mutant of Brevibacterium ammoniagenes. A manganese-insensitive mutant, KY 13105, of Brevibacterium ammoniagenes which accumulates considerable amounts of 5' inosinic acid (IMP) in the presence of 100 to 1,000 mug of Mn(2+) per liter was obtained from an IMP-producing mutant of a manganese-sensitive strain, KY 13102. The effects of Mn(2+) at 0 to 30 mug/liter on IMP accumulation by KY 13105 were similar to those by KY 13102. However, the accumulation of IMP by KY 13105 was not affected by 100 to 1,000 mug of Mn(2+) per liter, showing a clear difference from KY 13102. The accumulation of IMP by KY 13105 was always accompanied by cellular morphological changes irrespective of Mn(2+) concentration. In the presence of Mn(2+), factors which affect IMP accumulation by KY 13105 were examined. Most of the nutrients tested stimulated IMP accumulation at a relatively low concentration (2 g/liter). Iron, calcium, and zinc were found to be essential for IMP accumulation and were independent of Mn(2+). Biotin regulated the growth but not the accumulation of IMP. Under limited or surplus amounts of Mn(2+), the dynamics of IMP fermentation were followed. Under both conditions, the fermentations proceeded in a similar way. The morphological changes were found to be closely related to IMP accumulation.


Paramedical education in the field of rehabilitation in Canada.


Paramedical education in Israel.

Paramedical education in Israel.


And now to carry the torch of Aesculapius.


Paramedical education in rehabilitation in South America.


Epinephrine response differences in field--dependent and field-independent subjects.


Sensory mechanisms of homing in Salmonid fish. I. Introductory experiments on the olfactory sense in grilse of Baltic salmon (Salmo salar).


The treatment of congenital dislocation of the hip by the Pavlik strap brace.


Dentated inner femoral condyle. Uni-femoral condylar lysis--sequential to osteoarthritis of the knee.


Accessory extensor pollicis longus.

Accessory extensor pollicis longus.


A modification of the Jordan splint.

A modification of the Jordan splint.


Polymyalgia rheumatica.

Polymyalgia rheumatica.


Effect of relative humidity on the stability of Mycoplasma pneumoniae exposed to simulated solar ultraviolet and to visible radiation.


Immediate or early fitting of artificial limbs in the post-operative period.


Grafting aortic tissue to sclera.

Grafting aortic tissue to sclera.


The effect of p-chloromercuribenzoate on liver polysomes.


3 cases of cutaneous schistosomiasis of the vulva in 3 African women.


Parasitic disease in African and European.


Acute renal failure in urinary schistosomiasis.


Rural medicine.

Rural medicine.


The problem of communications in medical practice in East Africa.


Rural mobile medicine in Kenya.

Rural mobile medicine in Kenya.


The value of mobile medicine.

The value of mobile medicine.


Experience with a radiological method of diagnosing lactase deficiency.


Laboratory evaluation of some fungicides against Leptosphaeria salvinii Catt.


Evaluation of some fungicides and antibiotics for the control of angular black spot of legumes.


Aureofungin as a preharvest and postharvest peach fungicide.


Field trials with some fungicides and antibiotic aureofungin in control of angular black spot of black gram and green gram.


Neomycin production by Elytrosporangium brasiliense.


Experiences with hamycin in mycotic infections.


Characterization of actiduins producing streptomycete.


Control of early blight of potato in Maharashtra State.


Congenital microphthalmos with orbital and orbitopalpebral cysts. (Clinical and histopathological studies).


Posterior embryotoxon.

Posterior embryotoxon.


Topical cortisone in the treatment of Mooren's ulcer.


Bilateral multiple congenital pits in the optic disc with opaque nervefibres and maculopathy.


A case of syphilitic anterior uveitis with posterior chamber hemorrhage.


Unusual findings in methyl alcohol poisoning.


Intraocular pressure in young diabetics and its relationship with diabetic retinopathy.


Effect of topical steroids on intraocular pressure in young diabetics.


Entropion operation of upper lid in trachoma. A modification of 'inversio tarsi' operation.


Urobiotic in the treatment of urinary tract infection (a clinical and bacteriological study).


A clinical study of chronic cor pulmonale in Northern India.


Arrhythmias complicating acute myocardial infarction.


Studies in environmental health of Banaras Hindu University Township.


Congestive heart failure.

Congestive heart failure.


Carbon monoxide poisoning in two sisters.