An XXY sex-chromosome constitution in a dog with testicular hypoplasia and congenital heart disease.


Inactivation of tetrameric rabbit muscle pyruvate kinase by specific binding of 2 to 4 moles of pyridoxal 5'-phosphate.


Glycosidases of aspergillus niger. II. Purification and general properties of 1,2-alpha-L-fucosidase.


The three-dimensional structure of ribonuclease-S. Interpretation of an electron density map at a nominal resolution of 2 A.


Interactions of bilirubin with bovine serum albumin in aqueous solution.


The carboxymethylation of bovine alpha-lactalbumin.


Synthesis of gamma-dimethylamino-alpha-phenylcycloalkyl propionates as potential analgetics.


Aroylpiperidines and pyrrolidines. A new class of potent central nervous system depressants.


4'-Fluoro-4-(1,4,5,6-tetrahydroazepinol[4,5-b]indol-3(2H)-yl)butyrophenones.


Irreversible enzyme inhibitors. CLXVI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 2,4-diamino-5(3,4-dichlorophenyl)pyrimidine with 6 substituents and some factors in their cell wall transport.


Alcohol consumption and its circadian distribution in mice.


Toxoplasma gondii infections.

Toxoplasma gondii infections.


A comparison of the chemical tests for oestrogens used in equine pregnancy diagnosis.


Biosynthesis of animal and plant bufadienolides. Parallel experiments with pregn-5-en-beta-ol-20-one-20-14C in Scilla maritima and Bufo paracnemis.


A comparison of methods for the extraction of amino acids from fungal mycelium.


Presence and adaptive changes of citrate cleavage enzyme in the yeast Rhodotorula gracilis.


Effect of methyl phenyldiazenecarboxylate (azoester) on the germination of the fungus Trichoderma viride.


Vitellogenesis in Bidderian oocytes after diethylstilbestrol dipropionate treatment on Bufo bufo adult males.


Titration of cholera antitoxin levels by passive hemagglutination tests using fresh and formalinized sheep erythrocytes.


Effect of ovarian hormones upon milk yield in the rat.


Studies on maintaining the lactational diestrum after early litter weaning.


Cytotoxic action of an antiserum to soluble collagen on tissue culture of fibroblasts.


Separation and prolongation of viability of human lymphocytes for tissue typing. Evaluation of a technic.


Studies of the induction of interferon system by nonreplicating Newcastle disease virus.


Fertilization in ewes treated with progesterone and equine anterior pituitary extract.


Effect of hypothalamic deafferentation on the control of luteinizing hormone secretion.


10th annual Ruminant Nutrition Conference. Amino acids in ruminant nutrition. Introductory remarks.


Receptivity scores of female rats stimulated either manually or by males.


Serum and pituitary prolactin levels before, during, and after puberty in female rats.


Medicine and law: student perspectives.

Medicine and law: student perspectives.


Selected topics related to the amino acid nutrition of the growing ruminant.


Amino acid nutrition of lactating ruminants.


Amino acid metabolism in ruminant nutrition. Lactating ruminants.


Vascular radiology in liver disease.

Vascular radiology in liver disease.


Amino acid requirements of ruminants.

Amino acid requirements of ruminants.


Voltage and time dependence of excitatory sodium current in cooled sheep Purkinje fibres.


Responses of single cells in the olfactory bulb of rabbits to air flow.


Effects of unilateral ovariectomy on ovulation and cycle length in 4- and 5-day cycling rats.


Influence of unilateral ovariectomy on follicular development in cycling rats.


Orotic acid in food milk powders.

Orotic acid in food milk powders.


Aflatoxin and Indian childhood cirrhosis.


Comparative study of polyribonucleotides in aqueous and glycol solutions.


Methylation of histidine-57 in alpha-chymotrypsin by methyl p-nitrobenzenesulfonate. A new approach to enzyme modification.


Interaction of clupeine with deoxyribonucleic acid. II. Optical rotatory dispersion studies.


Monoamine fluorescence in CNS smears: sensitive and rapid visualization of nerve terminals without freeze-drying.


Ultraviolet difference spectra in human hemoglobin. I. Difference spectra in hemoglobin A and their relation to the function of hemoglobin.


The primary structure of porcine pancreatic ribonuclease. I. The distribution and sites of carbohydrate attachment.


The structure of the terminal ganglionic mass of the locust, Schistocera gregaria (Forskäl).


The primary structure of porcine pancreatic ribonuclease. II. The amino acid sequence of the reduced S-aminoethylated protein.


Transglutaminase levels during development of allergic orchitis.


Gonadotrophin inhibition by the synergistic action of vasopressin and oxytocin.


Aberrant karyotypes and spontaneous abortion in a Japanese family.


Serum lipids and the death of spawning Pacific salmon.


Evidence of a cholinergic nervous mechanism mediating the autoregulatory dilatation of the cerebral blood vessels.


Free flow micropuncture studies of glucose transport in the rat nephron.


Acute superior mesenteric artery syndrome in the severely burned patient.


Biologic mode of action of the Lippes loop in intrauterine contraception.


The health administrator--expert or amateur?


Information on the 1970 U.S. census.

Information on the 1970 U.S. census.


Letter to the editor: the 1970 U.S. census.


Letter to the editor: the 1970 U.S. census. Reply from the Census Bureau.


National health insurance.

National health insurance.


Lethal effects of kinetic energy on the schistosoma larva carrier snail.


Letter to the editor: public health education.


Smoking disease: a self-inflicted injury.


Standards needs in controlling radiation exposure of the public.


Misuse and abuse of diagnostic x-ray.

Misuse and abuse of diagnostic x-ray.


The use of standards in the administration of environmental pollution control programs.


A waterborne outbreak of gastroenteritis in western New York State.


Factors affecting diffusion of innovations among health professionals.


The community health education project: "bridging the gap".


Improved use of health professionals in New York City schools.


Increasing the effectiveness of school-community health programs--a nursing viewpoint.


Educational qualifications of management personnel in health agencies.


Committee on Affiliated Associations and Regional Branches: report of the Chairman, 1969.


Committee on Evaluation and Standards: report of the Chairman, 1969.


Synthetic studies on insect hormones. IX. Stereoselective total synthesis of a racemic boll weevil pheromone.


Relationship between quantitated precordial movement and left ventricular function.


Effects of internal irradiation of the mammary gland with 144cerium-144praseodymium.


Pancreatic amylase secretion by young calves.


Changes in plasma free fatty acids and triglycerides in dairy cattle after dosing with coffee or caffeine.


Idiopathic thrombocytopenic purpura in childhood. An approach to therapy.


How to start a suicide prevention center without really trying.


Treating like with like.

Treating like with like.


Inhibition of gastric acid secretion in man by peptide analogues of cholecystokinin.


Ductus arteriosus and the mechanism of closure.


Survey of occupational health practices by nurses in Victoria, Australia.


An experience with annual pelvic examinations in 290 women workers.


A profile of occupational health nursing.


Evaluation of a home test for cervical cancer.


Does the industrial nurse protect employees' physical, mental, and social health?


Cardiac conduction system: fetal and postnatal development.


Neurophysiological correlates of the intellectual function of elderly persons living in the community.


A simple alignment test for the interference optics of the ultracentrifuge.


New and sensitive reaction for automatic determination of inorganic phosphate and its application to serum.


An evaluation of the equivalent level correction for schlieren data in sedimentation velocity experiments.


Chronic exteriorization of vascular cannulas and ECG electrodes from the ovine fetus.


Changes in absorption spectrum and crystal structure of triose phosphate isomerase brought about by 2-phosphoglycollate, a potential transition state analogue.


Unusual spermatozoan formations in the epididymis of the flying squirrel (Glaucomys volans).


Histology of the vaginal epithelium of the sow during oral administration of methallibure (ICI 33828).


Effects of castration at birth in hamsters of both sexes on luteinization of ovarian implants, oestrous cycles and sexual behaviour.


Preliminary observations on the reproductive cycle of male fallow deer (Dama dama L.).


Determination of follicle growth rate in the ovary of the immature mouse.


Ultrastructural features of blastocyst attachment and trophoblastic invasion in the rat.


Sex chromosomes and reproductive anatomy of some intersexual marsupials.


Identity of chimpanzee with human fibrinopeptides.


Absence of antimicrobial substances in the egg capsules of millipedes.


Audiological findings in hearing loss secondary to maternal rubella.


Testicular leukemia.

Testicular leukemia.


The ovarian vein syndrome.

The ovarian vein syndrome.


Granulomatous lesions in the breast presenting as carcinoma.


The clinical use of intraperitoneal cephalothin.


Primary malignant tumors of the gallbladder: report of 43 cases.


The use of kinetic models to analyze differentiation.


Enzymatic RNA synthesis on irradiated DNA.


Soluble epidermal proteins.

Soluble epidermal proteins.


Phosphorus in histones.

Phosphorus in histones.


Failure of 5-alpha-dihydrotestosterone to elicit estrous behavior in the ovariectomized rabbit.


Ultrastructural variants among peripheral vesicles and vacuoles of murine embryo cell strains.


The formations of blood islands in dissociated-reaggregated chick embryo yolk sac cells.


Effect of metabolic inhibitors on macromolecular synthesis and early development in the mouse embryo.


Altered gravitational field effects on the fertilized frog egg.


Long-term cultivation of dissociated neurons from embryonic chick dorsal root ganglia in the Rose chamber.


Intracellular enzyme kinetics in triiodothyronine-grown ascites cell cultures.


Mitotic activity in cultured brown fat cells.


Effect of cell number on the type and stability of differentiation in amphibian ectoderm.


Developing fertilization membranes.

Developing fertilization membranes.


Food animal practice--our proud legacy.

Food animal practice--our proud legacy.


Evaluation of transplantation of the long digital extensor tendon for correction of anterior cruciate ligament rupture in dogs.


Closure of ocular lacerations with an adhesive.


Pelodera strongyloides in association with canine dermatitis in Wisconsin.


Veterinary medical services: utilization by dog and cat owners.


Effects of uterine curettage in the mare.


Diagnosis and treatment of carbaryl poisoning in swine.


The fine structure of human foetal tissues.


Innervation of the ovary in cats.

Innervation of the ovary in cats.


Ultrastructural features of spermiogenesis in man.


A cephalothoracophagus pig.

A cephalothoracophagus pig.


The distribution of catecholamines and 5 HT in the rat uterus.


Circulating phytosterols in normal females, lactating mothers and breast cancer patients.


Metabolism of Fenac herbicide in a lactating cow.


Metabolism of radioiodide by lactating goats given iodine-131 for extended periods.


Bilateral renal hypoplasia with oligonephronia.


Induction of translocations in mouse spermatogonia by X-ray doses divided into many small fractions.


Induction of bobbed (BB) mutations by polycyclic aromatic carcinogens in Drosophila.


Picornavirus-like crystals in subacute polymyositis.


"End-plate noise" in electromyography.

"End-plate noise" in electromyography.


Activity of single motor units during isometric tension.


Some regional circulatory abnormalities following experimental cerebral infarction.


Cerebrospinal fluid electrolyte disturbances in neurological disorders: with special reference to inorganic phosphate.


Developmental Gerstmann syndrome.

Developmental Gerstmann syndrome.


Cerebral phycomycosis in a heroin addict.


Sensory polyradiculoneuropathy following spinal anesthesia; a clinicopathologic study.


The familial occurrence of intracranial aneurysms.


Isoniazid self-poisoning.

Isoniazid self-poisoning.


Considerations in anesthetic management for animal experimentation.


Postinfusion phlebitis.

Postinfusion phlebitis.


Blood gases and pH studies in patients before and during upper abdominal surgery.


Prolonged femoral arterial catheterization for intensive care.


Long-term study of patients successfully resuscitated following cardiac arrest.


Gene amplification in oocytes with 8 germinal vesicles from the tailed frog Ascaphus truei Stejneger.


Anesthesia and digitalis toxicity. V. Effect of the vagus on ouabain(ŕ)-induced ventricular automaticity during halothane.


Co-orientation stability by physical tension: A demonstration with experimentally interlocked bivalents.


Indirect monitor of blood pressure.

Indirect monitor of blood pressure.


Evaluation of intracutaneous testing for investigation of allergy to local anesthetic agents.


The spatial relationship of the X and Y chromosomes during meiotic prophase in mouse spermatocytes.


Maturation of the mouse oocyte in vitro. II. Anomalies of first polar body formation.


Cardiac arrhythmia after succinylcholine.


Thiopental and oxygen consumption.

Thiopental and oxygen consumption.


Triploidy in man. Report of a case and a discussion on etiology.


Further studies on the sex-chromosome systems of the American leaf-nosed bats (Chiroptera, Phyllostomatidae).


Effects of propanidid on adrenocortical function in man.


Pulmonary embolism during anesthesia: a case report and review of literature.


Sectional frame as mechanical aid for administration of spinal and epidural anesthesia.


Chromosome studies of pocket gophers, genus Thomomys. II. Variation in T. bottae in the American southwest.


The chromosomes of the order Crocodilia.


Combined light general and local anesthesia for cataract surgery.


Effect of carbobenzoxy derivatives of amino acids on glutamine synthesis and gamma-glutamyl transfer.


An inherited glutathione deficiency and a concomitant reduction in potassium concentration in sheep red cells.


Reversible lenticular opacities induced in rats by emotional stress.


Decreasing prevalence of trichinella spiralis in dogs of Iowa.


Geographic distribution of Gongylonema pulchrum, Gongylonema verrucosum, and Paramphistomum liorchis in white-tailed deer of the southeastern United States.


Influence of fertilization on ovogenesis in Ancylostoma caninum.


A new genus of bat flea (Siphonaptera: Ischnopsyllidae) from the Himalayas.


Pharyngostomum cordatum from the domestic cat (Felis catus) in India.


Dirofilaria immitis in the cerebral arteries of a dog.


Eimeria sprehni Yakimoff, 1934, and E. causeyi sp. n. (Protozoa: Eimeridae) from the Canadian beaver, Castor canadensis.


Dimetridazole, a systemic treatment for bovine venereal trichomoniasis. 3. Trials with cows.


Exposure of kittens and puppies to single metacercariae of Paragonimus westermani from Taiwan.


Electron microscope and histochemical studies on the eggs of Hymenolepis diminuta.


Hazard in the nursery.

Hazard in the nursery.


A comparison of the temperature curves recorded over normal and abnormal breasts.


Indiana University to offer M.P.H. degree.


Isolation of an isozyme of soybean lipoxygenase.


Nursing care for the alcoholic.

Nursing care for the alcoholic.


Sequence studies of the Fd section of the heavy chain of rabbit immunoglobulin G. A partial amino acid sequence was given by Cebra, Steiner & Porter (1968b) of the N-terminal half of the heavy chain of rabbit immunoglobulin G. This was extended and in part corrected to give a continuous sequence of 136 residues, which together with other work accounts for three-quarters of the total sequence. Evidence is given suggesting that there is a limited region of 10-15 residues that are exceptionally variable in the heavy chains from pooled rabbit immunoglobulin G.


The disulphide bonds of the heavy chain of rabbit immunoglobulin G. Six peptides containing eight half-cystine residues were isolated in good yield, after either oxidation or reduction and carboxymethylation of fragment C-1, which contains the N-terminal half of the heavy chain of rabbit immunoglobulin G. The sequences of five of these peptides had been reported previously (Cebra, Steiner & Porter, 1968b; Wilkinson, 1969) and that of the sixth was established. Other peptides containing half-cystine residues were isolated in much lower yield and are presumed to be derived from minor sequence variants. The cystine-containing peptides from enzymic digests of whole immunoglobulin G and Fc fraction were studied by several techniques and the results obtained enable us to put forward a scheme of the arrangement of the inter- and intra-chain disulphide bonds.


Advantages and limitations of a simplified colorimetric assay for ATP: creatine phosphotransferase activity of human serum.


Nitrogenous compounds immobilized in an aged rat.


Radiography of the canine colon using different contrast agents.


Surgical correction of cranial dislocation of the scapulohumeral joint in a dog.


Sporadic bovine encephalomyelitis.

Sporadic bovine encephalomyelitis.


Clinico-pathologic conference from the School of Veterinary Medicine, University of Pennsylvania.


The veterinarian and product liability.

The veterinarian and product liability.


Cytotoxic compounds. X. Carbamates derived from NN-bis-(2-chloroethyl)-m- and NN-bis-(2-chloroethyl)-p-phenylenediamine.


The synthesis of potential insecticides. II. Carbamic esters of 4-alkylthiopyrazolones.


Steroids. 3. Pyrolysis of maleic anhydride and maleic ester adducts of 9,11-epoxy-5,7-dienes.


Spontaneous perforation of the colon in the newborn.


Variations in pedometer activity during the menstrual cycle.


Effect of gestational and maternal age in early abortion.


Inhibition of biologic activity of poly I: poly C by human plasma.


Maintenance of pregnancy in protein-deficient rats with dietary supplements of methionine.


Rat ovarian 3-beta-hydroxysteroid dehydrogenase: normal developmental appearance in tissue culture.


Treatment of a severe phobia for birds by hypnosis.


Drug effects on gastric secretion and stress gastric hemorrhage in the rat.


Otognathia in a neonatal lamb.

Otognathia in a neonatal lamb.


Toxicity of larger-than-recommended doses of naphthalophos to cattle, sheep, and goats.


Splenic rupture in a newborn lamb.

Splenic rupture in a newborn lamb.


Charged and neutral ion carriers through bimolecular phospholipid membranes.


Federal Bureau of Narcotics lists 15 dont's as physician safeguards.


Identification and distribution of paraventricular units excited by stimulation of the neural lobe of the hypophysis.


Remarks on special emphasis programs of the national institute of allergy and infectious diseases.


Renal clearance of 15 plasma proteins in renal disease.


Behavioral abnormalities in young adult pigs caused by malnutrition in early life.


Ammonia metabolism in rumen bacteria and mucosa from sheep fed soy protein or urea.


Developmental morphology of the pineal complex in doves and pigeons (Aves; Columbidae).


Effect of source and level of protein on mineral utilization by the baby pig.


Cyclical changes in the fine structure of bovine endometrial gland cells.


A phenomenological theory of muscular contraction. I. Rate equations at a given length based on irreversible thermodynamics. A phenomenological theory for contracting muscle based on irreversible thermodynamics and the sliding filament theory is developed. The individual cross bridges, considered as subunits, are viewed as linear energy converters with constant transport coefficients. With this view of the subunits, phenomenological equations applicable to the whole muscle are obtained. The transport coefficients are shown to be a function of a single parameter which is the number of activated cross bridges at any instant. By requiring Hill's force-velocity relation (1) to be satisfied, the response of the muscle is related to the number of activated cross bridges. The resulting theory differs significantly from the theory developed by Caplan (2) and a comparison of the theories is presented. The theory is shown to correlate well with the heat data of Woledge (3) for a tortoise muscle and gives a value of Y (ratio of chemical affinity to enthalpy of reaction) equal to 0.945. The comparison of the theory with Hill's frog muscle data (1) and (4) is also encouraging. In part II of this series, length variations are considered and the resulting theoretical predictions are shown to be consistent with experimental data.


Sustained release hormonal preparation. 4. Biologic effectiveness of steroid hormones.


The clinical applications of beta blockade.


The external bladder sphincter in paraplegia.


Secondary amenorrhea with inappropriate lactation. Observations on etiology, estrogen-gonadotropin interrelationships, the behavior of human growth hormone, and the response to treatment.


Respiratory distress in the newborn; value of roentgenography in diagnosis and prognosis.


Biochemical changes in different parts of the rabbit fallopian tube during passage of ova.


Strategies for effective utilization of underprivileged youth in public health education.


Evaluation of continuing education.

Evaluation of continuing education.


Public health and the law. Health planning agencies: a legal crisis?


Activity of leptospires and their products on L cell monolayers.


Non-medical use of drugs.

Non-medical use of drugs.


Thrombocytopenic purpura and chickenpox.


Therapeutic orphans 1970.

Therapeutic orphans 1970.


Vitamin K requirement of normal infants on soy protein formula. Does 27 micrograms of vitamin K per liter meet the minimum daily requirement?


A short synthesis of the sex pheromone of the pink bollworm moth.


Thrombophlebitis of left spermatic vein and pulmonary thromboembolism. Cure by ligation.


An interdisciplinary approach to functional mental retardation.


The perceived adequacy of programming in mental retardation.


Effect of pregnancy sera on isolated lysosomes.


The adolescent in industry.

The adolescent in industry.


Aseptic meningitis associated with ECHO virus, type 9: an outbreak in Norfolk, Virginia.


Resistance to bacterial infection induced by statolon and pyran. The antibacterial properties of statolon and pyran were compared with those of bacterial endotoxin and found to be similar. Although high resistance was transient, it was followed by immunity of the same order as in mice infected without pre-treatment with the interferon inducers.


Viral susceptibility range of the fathead minnow (Pimephales promelas) poikilothermic cell line. The viral susceptibility range of a poikilothermic cell line derived from the fathead minnow (Pimephales promelas) (FHM) to infection by a number of homoiothermic viruses representing most of the presently recognized viral groups and a member of the psittacosis-lymphogranuloma-trachoma group of agents was studied. All infectious agents, except poliovirus types 1 and 3, infectious bursal agent, and an avian infectious bronchitis virus (IBV) strain, readily multiplied in the FHM cell culture system, producing a detectable cytopathic effect. Although inconclusive evidence was obtained with two other avian IBV strains, these results indicated the ability of the FHM cell culture system to readily support the propagation of a variety of cytopathogenic homoiothermic viral agents.


Pathogenicity of Salmonella gallinarum after metabolic injury by freezing. Freezing (-75 C) and storage (-20 C) of a cell suspension of Salmonella gallinarum resulted in a heterogeneous population of dead, metabolically injured, and unharmed cells. Injured cells constituted as much as 40% of those surviving freezing and storage for 1 day. Replica plating of frozen and thawed cells indicated metabolic injury was repairable and not a stable mutation. Penicillin was used to increase the ratio of injured to uninjured cells from a frozen and thawed cell suspension. Pathogenicity was evaluated by observing per cent mortality after injecting injured or uninjured cells into separate sets of chicks. Mortality differences between wholly uninjured and predominantly injured populations were small and consistent (5% level) with a hypothesis of no difference.


Cytogenetics of inherited partial sterility in three generations of the large milkweed bug as related to holokinetic chromosomes.


Translocations between eu- and heterochromatic chromosomes, and spermatocytes lacking a heterochromatic set in male mealy bugs.


Distribution of chromosomes in metaphase plates of Mesocricetus newtoni.


Parental influence on X-autosome translocation-induced variegation in the mouse.


The surface and internal structure of metaphase chromatin.


Optical diffraction and translational reinforcement of microtubules having a prominent helical wall structure.


Carbon dioxide fixation by mouse embryos prior to implantation. Mouse embryos in the stage of development prior to implantation were cultured in vitro in a medium that contained radioactive bicarbonate. The radioactivity was incorporated into the proteins and nucleic acids that were acid soluble. Uptake of radioactivity occurred into protein in the unfertilized ovum and was highest in all fractions in the early blastocyst stage. No incorporation was detected in the lipid fraction.


The binding of calcium and magnesium to actomyosin and its modification by natural tropomyosin.


The efficacy of optokinetic stimuli of different field radiances as shown to a rabbit.


Studies on blood-pressure regulation by the use of a baroreceptor analog.


Functional and organic.

Functional and organic.


Hormonal control of spermatogenesis in the cockroach, Periplaneta americana (L.).


The effect of infection with fowl plague virus on protein synthesis in chick embryo cells.


The DNAs of three parvoviruses.

The DNAs of three parvoviruses.


Isolation of temperature-sensitive mutants and the construction of a preliminary genetic map for influenza virus.


Rubella virus-specific ribonucleic acids in infected BHK21 cells.


Interferon production by myxoviruses in chick embryo cells.


On psychodynamics and clinical research methodology.


Vitamin B12 concentration of serum and tissues of B12-depleted rats.


Epidemiologic investigation of an outbreak of leptospirosis in the Upper Galilee, Israel.


Availability of milk folate. Studies with cow's milk in experimental folic acid deficiency.


Ability of the house fly, Musca domestica, to ingest and transmit viable spores of selected fungi.


Effect of an oral contraceptive on spontaneous running activity of female rats.


Inversion of the cecum into the colon of a dog.


Treatment of fractures with Hirschhorn compression plates.


Bronchoscopy in the dog and cat.

Bronchoscopy in the dog and cat.


Liver fluke infection in a cat.

Liver fluke infection in a cat.


Biomechanics of pedal rotation in equine laminitis.


The Controlled Dangerous Substances Act of 1969.


Congenital patellar ectopia in a foal.

Congenital patellar ectopia in a foal.


Evaluation and proposed applications of a one-step method for isolation and identification of Streptococcus agalactiae.


What is your diagnosis?

What is your diagnosis?


Retropubic vesicourethropexy.

Retropubic vesicourethropexy.


Human serum proinsulin.

Human serum proinsulin. Gel filtration of human serum extracts on Bio-Gel P-30 columns produced two peaks of material reactive with insulin antisera. The earlier eluting fraction appeared at the elution position of proinsulin (serum proinsulin-like component, PLC) while the second fraction corresponded in elution volume to insulin. In assays using porcine insulin-(131)I and an antiserum against porcine insulin, human pancreatic proinsulin was less reactive than human insulin. Serial dilutions of the serum PLC in the immunoassay showed immunological identity with the human proinsulin standard. Partial tryptic digestion of the serum PLC yielded products with increased immunological reactivity as estimated with insulin as the standard. With larger amounts of trypsin, all the serum PLC was converted to insulin-like components (desthreonine and desoctapeptide insulin). On the basis of these results we conclude that the earlier eluting fraction of human serum extracts is proinsulin. The fasting values of proinsulin in normal subjects ranged between 0.05 and 0.4 ng/ml, representing from 5 to 48% of the insulin concentration. In one subject the values of proinsulin were higher than those of insulin. After oral administration of 100 g of glucose, the proinsulin levels tended to rise similarly to insulin. Three obese patients with hyperinsulinemia had higher fasting levels of proinsulin and a greater increase after glucose than the normal subjects. As the high levels of proinsulin coexisted with raised insulin concentration in these obese subjects, the relative proportions of the two hormones were in the same range observed in the normal group. Thus hyperinsulinemia in these obese subjects was not accompanied by an increase in the fraction of serum proinsulin. When the values for serum proinsulin were expressed as percentage of the insulin levels, there was a decrease in the per cent proinsulin in the first hour of the glucose tolerance test. After the second hour, the per cent tended to rise towards the fasting levels.


External sphincterotomy in paraplegics: technique and results.


The archegoniate revolution.

The archegoniate revolution.


Wildlife rabies: a European problem.

Wildlife rabies: a European problem.


Ruby laser photocoagulation of early diabetic neovascular retinopathy. Preliminary report of a long-term controlled study.


Active length-tension relations compared in isometric, afterloaded and isotonic contractions of cat papillary muscle. Their dependence on inotropic state.


Circulatory changes during growth in the fetal lamb.


Molecular weight determinations and the influence of gel density, protein charges and protein shape in polyacrylamide gel electrophoresis.


The influence of oral contraceptive and progestational drugs upon the mechanical activity of the non-pregnant human uterus in vivo.


Thiocyanate binding with modified bovine plasma albumins.


Detection of a conformational change in an antihapten--antibody system upon interaction with divalent hapten.


Oxygen quenching of pyrenebutyric acid fluorescence in water. A dynamic probe of the microenvironment.


Calf intestine adenosine deaminase. Substrate specificity.


Kinetics of carboxypeptidase A. II. Inhibitors of the hydrolysis of oligopeptides.


Nonphosphorylated serine residues in phosvitin.


Mechanism of the oxidative dephosphorylation of the phosphoprotein phosvitin.


Correlation between subunit interactions and enzymatic activity of phosphorylase a. Method for determining equilibrium constants from initial rate measurements.


Mode of action of the alpha toxin of Staphylococcus aureus.


Results and randomized original treatment in cases of pulmonary tuberculosis with isoniazid-streptomycin versus isoniazid-thiocarlide.


Strategies within hypnosis for reducing phobic behavior.


Effect of age of rat on development of hepatic carriers for bilirubin: a possible explanation for physiologic jaundice and hyperbilirubinemia in the newborn.


Antiandrogenic and antiuterotropic activities of three synthetic progestagens.


Peroxidatic activity of catalase.

Peroxidatic activity of catalase.


Ionisation of horse serum butyrylcholinesterase.


The inhibition of butyrylcholinesterase by methanesulfonyl fluoride.


Inhibition of thrombin by sarin.

Inhibition of thrombin by sarin.


Studies on the function of abnormal hemoglobins. I. An improved method for automatic measurement of the oxygen equilibrium curve of hemoglobin.


Structural studies on adenosine deaminase from calf intestinal mucosa.


The major genetic variant macropeptides of kappa-casein--a comparison of their amino acid contents and tryptic peptides.


Precipitation and crystallization of insulin in the presence of lysozyme and salmine.


Studies on the carboxyl-terminal tetrapeptide sequence of bovine serum albumin.


Crystallographic study of rabbit liver cytochrome b5.


Immunological studies in haemophilia.

Immunological studies in haemophilia.


Formulation of a morphine implantation pellet suitable for tolerance-physical dependence studies in mice.


Lexicon for today--2nd edition.

Lexicon for today--2nd edition.


Veterinary radiographic facilities.

Veterinary radiographic facilities.


Surgical removal of leiomyoma of the small intestine of the dog.


Observations on relative visceral organ weight and the lack of evidence for adrenal hypertrophy in clinical cases of Johne's disease.


Sheep husbandry in Norway.

Sheep husbandry in Norway.


The "cost" of Swann.

The "cost" of Swann.


Lens luxation in the Webster terrier.

Lens luxation in the Webster terrier.


Changes in psychological symptoms in women taking oral contraceptives.


Non-polar mechanism for micelle formation in aqueous solutions of Forssman hapten.


Atypical viral diseases. Recent data incriminates viruses in a variety of slowly progressive, degenerative diseases.


Management of prostatism. Indications for surgical intervention.


Surgery of the canine mouth and pharynx.


Glaucoma in the dog.

Glaucoma in the dog.


Comparative aspects of glaucoma.

Comparative aspects of glaucoma.


Some aspects of interdigital cysts in the dog.


Canine urolithiasis: incidence, chemical composition and outcome of 100 cases.


Uniquely oriented epidermal lipid.

Uniquely oriented epidermal lipid.


Courtship behaviour of some Drosophila melanogaster mutants.


Prentice Villa--the first year.

Prentice Villa--the first year.


Impoverished and ignored.

Impoverished and ignored.


Voluntary help in the field of sub-normality.


The long night.

The long night.


Interpretation of gas-blood ratio in PO2 polarography.


Activity in single hypoglossal fibers during cortically induced swallowing and chewing in rabbits.


Effect of hematocrit on pressure-flow relations for perfused isolated lobes of the canine lung.


Alkaloids from catecholamines in adrenal tissue: possible role in alcoholism. Epinephrine and norepinephrine condensed with acetaldehyde or with formaldehyde in dilute aqueous solution at neutral pH and room temperature to form 1,2,3,4-tetrahydroiso-quinoline alkaloids. Similar condensation reactions occurred in cow adrenal glands perfused with dilute aldehyde solutions at 37 degrees C. Biosynthesis of these alkaloids in vivo could play a role in altering an individual's behavior during and after the ingestion of alcohol.


Extraction of plasma insulin in radioimmunoassay for removal of nonspecific inhibitor and of circulating insulin antibody.


Australia antigen in chronic hepatitis in Australia. Of 53 cases of active chronic liver disease two were found to be carriers of Australia antigen Au (1)-an elderly woman with typical lupoid hepatitis and an elderly mortuary attendant with serologically atypical active chronic hepatitis. Au (1) was detected also in the serum of 7 out of 20 patients with clinically atypical acute hepatitis-one was an elderly Italian woman, one had hepatitis in the puerperium, and five had a history of transfusion or inoculation. The antigen was not found in 20 typical cases of infectious hepatitis in young people in 86 patients with other diseases. Antibody to Au (1) was present in only 2 out of 102 patients who had received numerous transfusions.We conclude, firstly, that Au (1) antigen is rare in white Australians (in keeping with the low incidence of serum hepatitis in Australia), and, secondly, that Au (1) positivity in hepatitis patients is associated with transfusions and with older age. We suggest that active chronic hepatitis and lupoid hepatitis may follow infection of susceptible individuals with Au (1)-positive hepatitis virus, but persistence of the virus in high titre does not appear to be necessary for chronicity of the disease.


Drug-induced hydrops in the fetal lamb.

Drug-induced hydrops in the fetal lamb.


Immunoreactive insulin in amniotic fluid.


Congenital adrenogenital syndrome and successful pregnancy. Report of a case.


Chain urethrocystography before and after urethrovesical suspension for stress incontinence.


Effect of radiation therapy on normal human lymph nodes and trunks: evaluation by "second-look" lymphography.


The treatment of recurrent endometrial carcinoma.


Ethnic differences in cancer in Hawaii.

Ethnic differences in cancer in Hawaii.


Acute toxicity of five insect chemosterilants, hemel, hempa, tepa, metepa, and methotrexate, for cockerels.


Investigating outbreaks of disease allegedly due to feedingstuffs.


Nutrition of the dairy heifer.

Nutrition of the dairy heifer.


A case of lice infestation.

A case of lice infestation.


Yolk sac tumors of the testis.

Yolk sac tumors of the testis.


Prolonged low-dosage administration of hexamethylmelamine (NC 13875).


Untreated ca-in-situ of the cervix.

Untreated ca-in-situ of the cervix.


Melanoma in twins. Cutaneous malignant melanoma in identical twins from a set of triplets.


On how little information controls so much behaviour.


Major difficulties in successful mental health program development on community level.


The serological diagnosis of arbovirus infections in newborns and infants.


The effect of seminal protease on sperm migration through cervical mucus.


Bromide space studies in infants of low birth weight.


Concentrations of progesterone in the plasma of mothers and infants at time of birth.


Bacterial endocarditis.

Bacterial endocarditis.


Sex ratios of newborns and schizophrenia.


Hyperphenylalaninemia: disaggregation of brain polyribosomes in young rats. A single injection of l-phenzylalanine in 7-day-old rats produtced disaggregation of brain polyribosomties and inhibition of in vitro protein synthesis in cell-free systems prepared from brain. Liver polyribosomes and in vitro protein synthesis in hepatic systems were not affected. In 4-week-old rats these effects on brain protein synthesis did not occur.


Proof of the enzymatic formation of 9-hydroperoxy-10-trans, 12-cis-octadecadienoic acid from linoleic acid by soya lipoxygenase.


Cocaine-like action of hexylguanidine on smooth muscle preparations.


Lipid metabolism in bone and bone cells. II. The in vitro incorporation of [32P] orthophosphate and [14C] serine into lipids of bone and bone cell cultures.


Generation of the proteolytic activity bound with alpha 2-macroglobulin during plasma clotting.


A study of the alkaline phosphatase activity in some commercial quality control sera with p-nitrophenyl phosphate and phenyl phosphate substrates.


Macroamylasemia: possible role of polysaccharide in composition of macroamylase.


Binding of bilirubin with lipid. A possible mechanism of its toxic reactions in mitochondria.


A study of the immunochemistry of three yeast mannans.


Relationships of thyrotropin to exophthalmic-producing substance. Purification of homogeneous glycoproteins containing both activities from [3H]-labeled pituitary extracts.


Some molecular properties of rhodanese.

Some molecular properties of rhodanese.


Nuclear pore flow rate. A characteristic for nucleocytoplasmic exchange of macromolecules and particles.


On the dynamics of action.

On the dynamics of action.


Two modes of Na extrusion in cells from guinea pig kidney cortex slices.


Respiratory response to arterial H+ at different levels of arterial PCO2 during hyperoxia or hypoxia.


Isolated toad skin epithelium: transport characteristics.


The thiosulphate (35S) space in the CNS of rats after ventriculo-cisternal perfusion.


The slow inward current and the action of manganese ions in guinea-pig's myocardium.


Core polymers of casein micelles.

Core polymers of casein micelles.


Hydrogen ion titration curves of the native bovine fibrinogen and of bovine fibrinogen denature of 5 M guanidine hydrochloride.


1-amino-1,3-dicarboxycyclohexane (cycloglutamic acid), a new glutamic acid analog and a substrate of glutamine synthetase.


Amino acid sequence analysis with methyl isothiocyanate. Resolution of the methylthiohydantoins by gas-liquid partition chromatography.


Lactose synthetase. Modification of carboxyl groups in alpha-lactalbumin.


Synthesis of glyceryl ethers by microsomal enzymes derived from fibroblasts (L-M cells) grown in suspension cultures.


A technique for the photography of fish scales.


Digestive proteases in the cyclostome Myxine glutinosa (L).


Porphyrin biosynthesis in the soybean callus tissue system. II. Improved purification and some properties of delta amino-laevulic acid dehydratase.


Steroids. XXXIV. 17-beta-hydroxy-5-beta, 14-alpha, 17-alpha-pregnan-20-one and related compounds.


Novel analgesics and molecular rearrangements in the morphine-thebaine group. XVII. Compounds related to the thebaine-maleic anhydride adduct.


Cytotoxic compounds. XI. Enol carbamates derived from alpha-chloro-alpha-phenylacetophenone.


Studies on the synthesis of Aspidosperma and related alkaloids. II. A synthetic approach to the C-21 oxygenated Aspidosperma alkaloids.


Tetracycline studies. 3. Trimethylsilyl derivatives of tetracyclines.


Ovarian regulation of the corpus allatum in the housefly, Musca domestica.


Inhibitory effects of colchicine on ciliogenesis in ectoderm of Xenopus laevis.


A study of Toxoplasma gondii infection in farm and non-farm groups in the same geographic location.


Heterogeneity of tropocollagen as investigated by chromatography on hydroxyapatite columns.


Methylnitrosourea-induced malformations of brain in SD-JCL rat.


Censorship, social control and socialization.


Psychosomatic specificity hypothesis testing.


Yeasts isolated from bumblebee honey from western Canada: identification with the aid of proton magnetic resonance spectra of their mannose-containing polysaccharides.


Development, organization, and degeneration of the Drosophila sperm flagellum.


A progressive change in the electrophoretic mobility of preaggregation cells of the slime mould, Dictyostelium discoideum.


An estimate of the amount of microtubule protein in the isolated mitotic apparatus.


Students and medicine.

Students and medicine.


Abdominal pregnancy carried to term following the treatment of pelvic tuberculosis.


Glanzmann's thrombasthenia and pregnancy.


Chlordiazepoxide and conditioned suppression.


Prognosis of stage 1 carcinoma of the prostate.


Behavioural effects in rats of morphine and amphetamine and of a combination of the two drugs.


A parallel study of the amnesic effects of cycloheximide and ECS under different strengths of conditioning.


The use of fish, especially goldfish, in alcohol research.


Psychological stess during pregnancy, effects on mothers and offspring.


Leptospirosis in wild animals.

Leptospirosis in wild animals.


Studies on the carriage of Pasteurella haemolytica in lambs.


The biology of Hyostrongylus rubidus. II. Repeated infection in young pigs.


Verminous pneumonia in East African antelopes.


Transmission experiments with a scrapie-like encephalopathy of mink.


Observations on arteriosclerosis, serum cholesterol and serum electrolytes in the wild African elephant (Loxodonta africana).


Mushroom worker's lung.

Mushroom worker's lung.


Vocational evaluation and successful placement of psychiatric clients in a vocational rehabilitation program.


Establishing an occupational therapy department in a community hospital.


Frequency of intestinal parasites in Africans.


Anthrax in the Mount Darwin area.

Anthrax in the Mount Darwin area.


Salmonellosis in man and animals in N.E. Scotland. A ten year review--1959-1968.


Rabies outbreak in Britain.

Rabies outbreak in Britain.


Effects of thermal conductivity and solute concentration on cryosurgery of the prostate.


The expression of differentiation by chick embryo thyroid in cell culture. I. Functional and fine structural stability in mass and clonal culture.


A preliminary crystallographic investigation of human L-type Bence-Jones protein.


Flattening, movement and control of division of epithelial-like cells.


Characterization of RNA molecules restricted to the nucleus in mouse L-cells.


An improved chemically defined culture medium for strain L mouse cells based on growth responses to graded levels of nutrients including iron and zinc ions.


Separation of gangliosides, corticosteroids and water-soluble non-lipids from lipid extracts by sephadex columns.


Home or hospital for chronic schizophrenia?


Combined care in obstetrics and commentary on future trends.


Thermal fractionation of outer fiber doublet microtubules into A- and B-subfiber components. A- and B-tubulin.


Synthesis of RNA in non-nucleate fragments of sea urchin eggs.


Segments from myosin rods.

Segments from myosin rods.


The lipids of thermophilic fungi: lipid composition comparisons between thermophilic and mesophilic fungi.


Cholesterol metabolism and vitamin B6. II. Intestinal cholesterogenesis in vitamin B6 deficient rats.


Straight and narrow: control of drugs.

Straight and narrow: control of drugs.


Cholesterol esters of milk and mammary tissue.


Differences in E and S chains from isoenzymes of horse liver alcohol dehydrogenase.


The epidemiology of sporotrichosis in the Transvaal.


The study and significance of colony dissociation in Candida albicans.


Psychopathology in bronchial asthmatic patients.


Priorities in the care of the mentally handicapped.


Immunohistological, microscical and neurochemical studies on encephalitides. IV. Subacute sclerosing (progressive) panencephalitis. Histochemical and immunohistological findings in tissue cultures derived from SSPE brain biopsies.


On the structure arising from the interaction of phospholipid micelles with headpiece-stalk sectors detached from the mitochondrial cristal membrane.


Thermodynamics of the denaturation of ribonuclease by guanidine hydrochloride.


Determination of interaction parameters for a generalized associating system from colligative data.


Determiniation of trypsin-inhibitor complex dissociation by use of the active site titrant, p-nitrophenyl p'-guanidinobenzoate.


Synthesis of polydeoxynucleotides using chemically modified subunits.


Low-molecular-weight, methylated ribonucleic acid species in Chinese hamster cell fractions absorb to bentonite.


Relaxation spectra of ribonuclease. VII. The interaction of ribonuclease with uridine 2',3'-cyclic phosphate.


Quantitative cleavage of a protein with N-bromosuccinimide.


Lactation suppresses adrenal corticosteroid activity and aggressiveness in rats.


Aggression and timidity: responses to novelty in feral Norway rats.


Suppression of interspecies aggression in the rat by several aversive training procedures.


Output pathways of hypothalamic mechanisms for sexual, aggressive, and other motivated behaviors in opossum.


Sulfur and selenium compounds related to acetylcholine and choline. X. Acetylhionocholine.


Nucleosides. LXIV. Fluoro sugar analogs of arabinosyl- and xylosylcytosines.


Drug crutches.

Drug crutches.


Alpha, alpha, alpha-trifluorotoluic acid (5-nitrofurfurylidene) hydrazides.


Polypeptide chain involved in the cross-linking of stabilized bovine fibrin.


Biochemical and behavioural effect of amphetamine in DMI and Ro 4-1284 induced hyperactivity.


The detection of a conformational change in the antibody molecule upon interaction with hapten.


Modification of carboxyl groups in the active site of trypsin.


Synthesis of a nuclear protein in G2-phase.


Isolation of a chromatographically unique glycopeptide from murine histocompatibility-2 (H-2) membrane alloantigens labelled with H3-fucose of H3-glucosamine.


Enzymatic and spectral properties of solubilized cytochrome P-450 from bovine adrenocortical mitochondria.


An endopeptidase in the uterine secretion of the proestrous rat and its relation to a sperm decapitating factor.


The response of histone fractions to x-irradiation in cultured Chinese hamster cells.


Fucosyltransferase found in human milk. Product of the Lewis blood group gene.


Preparation and properties of a complex of adenosine triphosphate with myosin, actomyosin, and subfragment 1.


Hybridization of native and chemically modified enzymes. II. Native and succinylated glyceraldehyde 3-phosphate dehydrogenase.


Kinetic study of the interaction between aspartate aminotransferase and threo-beta-chloroglutamate.


Effect of pH on the binding of N-alkyl sulfates to bovine serum albumin.


Molecular conformation of egg-white lysozyme and bovine alpha-lactalbumin in solution.


Changes in the proportion of 'H' and 'M' subunits of lactate dehydrogenase in rat uterus during an oestrous cycle.


The effects of Na+ and K+ on the citrate activation of prothrombin and on the esterase activities of thrombokinase.


Denver's Children's Hospital.

Denver's Children's Hospital.


Relations between the electrogastrogram and gastric ulceration during exposure to stress.


The service guide.

The service guide.


Health manpower: what to do.

Health manpower: what to do.


The teaching of comprehensive patient care.


Civil disturbance and the health department.


Prescription for a planet. The Ninth Bronfman Lecture.


A multivariate analysis of sociopsychological factors in monks with myocardial infarctions.


Pneumoconiosis among anthracite coal miners in Pennsylvania.


Environmental health experiences in disaster.


Hurricane Beulah.

Hurricane Beulah.


A statistical study on the relationship between mental illness and traffic accidents--a pilot study.


Trends in public knowledge about health and illness.


The epidemiology of peptic ulcer in childhood.


Attitudes and satisfactions of low-income families receiving comprehensive pediatric care.


Community needs and how they relate to the school health program: S.H.A.R.P.--the needed ingredient.


Professionals and the community confront change.


Denver's preventive health program for school-age children.


Some factors influencing the outcome of consultation.


The disinfection of swimming pool waters. I. Comparison of iodine and chlorine as swimming pool disinfectants.


Committee on Public Policy: report of the chairman, 1969.


Committee on Research Policy: report of the chairman, 1969.


Committee on Health Manpower: report of the chairman, 1969.


Committee on Professional Education: report of the chairman, 1969.


Reactions to vaso-active agents of small vessels in the embryonic membranes of the developing chick.


Water pollution in a State Park: the government's liability.


Sympathetic nerve development in the brown adipose tissue of the rat.


Induction of superovulation in mature rats with gonadotrophins.


The metabolism of beta-carotene and other carotenoids in the brine shrimp, Artemia salina L. (Crustacea: Branchiopoda).


Epidemiological investigation of bovine virus diarrhea-mucosal disease in an unvaccinated dairy herd. A case report.


Experimental leptospirosis in pregnant ewes. VII. Pathogenesis of fetal infection and mechanism of abortion.


Molecular weight and quaternary structure of yeast L-lactate dehydrogenase (cytochrome b2). 2. Revised heme extinction coefficients and minimal molecular weight.


Isolation and characterization of porcine proelastase.


Activation and inhibition of acetylcholineesterase by toxogonin.


Indium, a versatile scanning agent.

Indium, a versatile scanning agent.


Non-specific esterase zymogram and histochemistry in the keratinization of tumors.


Acid report on acid.

Acid report on acid.


Estrous cycle changes after prenatal and neonatal injections of melatonin in normal and androgen-sterilized female rats.


Site of action of the inhibitory effect of estrogen upon lactation.


Changes in multiple unit activity of the brain during the estrous cycle.


Chromosomal damage in Chinese hamster cells grown in U.V.-irradiated medium.


Studies on the photo-C4-cyclo-addition reactions between skin-photosensitizing furocoumarins and nucleic acids.


Effects of light on viability and DNA synthesis of mammalian cells preincubated in media containing brominated pyrimidines.


Problems of prematurity.

Problems of prematurity.


Root-shift in eel hemoglobin.

Root-shift in eel hemoglobin.


Gas exchange of the pregnant uterue os anaesthetized and unanaesthetized guinea pigs.


Who should go to E.S.N. schools?

Who should go to E.S.N. schools?


Meeting parents on home ground.

Meeting parents on home ground.


Stretching their learning skills.

Stretching their learning skills.


The changing tune of deafness.

The changing tune of deafness.


Preview of the 1970 census.

Preview of the 1970 census.


The rapid examination of pre-race samples of greyhounds' urine and some experiences of its use.


An agent possibly associated with swine dysentery.


Pulmonary mucormycosis (phycomycosis) in a chicken.


Nematode parasites of Oceanica. VII. New records from wild and domestic chickens (Gallus gallus) from Palawan (Philippine Islands), Sabah (Malaysia), and Taiwan.


Studies on Australian infectious bronchitis virus. IV. Apparent farm-to-farm airborne transmission of infectious bronchitis virus.


Paroxysmal torticollis in infancy.

Paroxysmal torticollis in infancy.


The development of a service-oriented psychiatric program in a disadvantaged area.


Correlation of psychiatric symptomatology and the menstrual cycle in an outpatient population.


Two forms of repair of DNA in mammalian cells following irradiation. When Chinese hamster cells are lysed on top of an alkaline sucrose gradient, in time a fairly discrete DNA-containing molecular species is released from an apparently more complex material. Small doses of X-radiation speed the resolution of this complex while large doses degrade the material released from it. Incubation after irradiation reverses both effects.


The antigenicity of pig insulin.

The antigenicity of pig insulin.


Changes in lactate dehydrogenase and esterase-specific activities, isozymic patterns, and cellular distribution during the growth cycle of PK cells in vitro.


A new method for the rapid isolation of chromosomes, mitotic apparatus, or nuclei from mammalian fibroblasts at near neutral pH.


Balint seminars and vocational training in general practice.


Cigarette smoking by Massachusetts physicians--1968.


Breast abscess.

Breast abscess.


Physiotherapy in veterinary medicine.

Physiotherapy in veterinary medicine.


Physiotherapy in the horse.

Physiotherapy in the horse.


The dog as a patient.

The dog as a patient.


Snakes and pneumonia.

Snakes and pneumonia.


Dachshund with a slipped disc.

Dachshund with a slipped disc.


Lateral luxation of the patella in a calf.


A cardio-hepatic syndrome in turkey poults.


A case of acute lead poisoning in a dog.


Vomiting and wasting disease in piglets. Virological and epidemiological studies.


Onchocerca gutturosa in cattle in Uganda.


An unusual sequel to the shower dipping of sheep with diazinon.


The excretion of megestrol acetate by beagle bitches.


Controlling liver-fluke: a case for wildlife conservation?


A case of rabies at Newmarket.

A case of rabies at Newmarket.


Parents and child.

Parents and child.


Care of mentally retarded.

Care of mentally retarded.


Further study on the activation of collagen proline hydroxylase in cultures of L-929 fibroblasts.


Rationale of hormonal therapy for infertility in the cow.


Abomasal ulceration and surgical correction.


Aleutian disease--an example of slowly-progressive infectious disease.


The relationship of the serum alkaline phosphatase to urinary hydroxyproline excretion in liver and bone diseases.


Analysis of initial and delayed effects of orchidectomy and ovariectomy on pituitary and serum LH levels in adult and immature rats.


Timing of sexual behavior in the female rat.


Site(s) of action of progesterone in blocking ovulation in the rat.


Isolation and characterization of an active-site peptide from triose phosphate isomerase.


American Museum of Natural History at 100.


Model for quantitative and qualitative control of mRNA translation in eukaryotes.


Binding activity of oestrogen receptors destroyed by iodination.


In vitro synthesis of pancreatic enzymes: effect of soybean trypsin inhibitor.


Preparation and properties of crosslinked water-insoluble catalase.


The metabolism of histone fractions. 3. Synthesis and turnover of histone f1.


Some properties of soybean lipoxygenase.


Tetrapyrrole biosynthesis in plant and yeast organelles.


Studies on the chemical modification of the tyrosine residue in bovine neurophysin-II. 1. Bovine neurophysin-II contains 1mol of tyrosine residue/10000g of protein. This residue could be readily nitrated with tetranitromethane. On hydrolysis and amino acid analysis 1mol of 3-nitrotyrosine was found/10000g of protein. Starchgel electrophoresis at pH8.5 showed that nitration had converted the native protein into a single, more acidic species. The increase in acidity was consistent with the observed fall in pK of the tyrosine hydroxyl from 9.2 in native neurophysin to 7.3 in the nitrated protein. Further, the absence of any intermediate species, even under conditions of minimum substitution, confirmed that the molecular weight of the monomer is 10000. 2. O-Acetylation of the tyrosine residue was carried out with N-acetylimidazole, in conjunction with the reversible blocking of amino groups by citraconylation. The degree of O-acetylation, determined spectroscopically, was 0.9mol of O-acetyltyrosine/10000g of protein. 3. The hormone-binding ability of modified protein was tested by equilibrium dialysis and was found to be unchanged by either nitration or O-acetylation of the tyrosine residue. 4. Interaction of neurophysin-II and [8-arginine]-vasopressin gave rise to a characteristic difference spectrum with a peak at 286.8nm and shoulder at 279.6nm. Part of this hyperchromicity is thought to result from entry of the tyrosine residue at position 2 in the hormone into the hydrophobic environment of the binding site. With nitrated neurophysin-II a second peak appeared at 436nm, showing that the tyrosine of the protein is also perturbed. The very large red shift (84nm) in this region suggests that the 3-nitrotyrosyl residue not only enters a more hydrophobic environment on protein-hormone interaction, but is caused to ionize more fully by the approach of some positively charged group.


An analysis of the interaction of protein with lipid monolayers at the air-water interface. 1. Measurements have been made of the interaction of cytochrome c, bovine serum albumin and synthetic oxytocin with low-pressure (2dyn/cm) monolayers of stearic acid, phosphatidylcholine and phosphatidylethanolamine. 2. [(14)C]Carboxymethylation of the cytochrome c and albumin followed by surface-radioactivity determinations have shown that only a proportion of the protein added to the subphase is bound to the monolayers and that initially the degree of binding is dependent on the protein concentration. The binding is irreversible in the sense that the adsorbed protein cannot be removed by transferring the film containing the interacted protein to a fresh subphase containing no protein. 3. Three successive types of interaction can usually be recognized. (a) Initially, whole molecules of protein penetrate the lipid film and occupy the same area as those of the protein spread at the air/water interface. (b) Above certain film pressures a part of each protein molecule, probably hydrophobic side chains, penetrates the film. The change in surface pressure per unit of bound protein is much smaller than in (a). (c) At higher film pressures, adsorption without penetration occurs. With cytochrome c this is initially dependent on a favourable electrostatic interaction.


Specific alkylation of a histidine residue in carnitine acetyltransferase by bromoacetyl-L-carnitine. Incubation of carnitine acetyltransferase with low concentrations of bromoacetyl-l-carnitine causes a rapid and irreversible loss of enzyme activity; one mol of inhibitor can inactivate one mol of enzyme. Bromoacetyl-d-carnitine, iodoacetate or iodoacetamide are ineffective. l-Carnitine protects the transferase from bromoacetyl-l-carnitine. Investigation shows that the enzyme first reversibly binds bromoacetyl-l-carnitine with an affinity similar to that shown for the normal substrate acetyl-l-carnitine; this binding is followed by an alkylation reaction, forming the carnitine ester of a monocarboxymethyl-protein, which is catalytically inactive. The carnitine is released at an appreciable rate by spontaneous hydrolysis, and the resulting carboxymethyl-enzyme is also inactive. Total acid hydrolysis of enzyme after treatment with 2-[(14)C]bromoacetyl-l-carnitine yields N-3-carboxy[(14)C]methylhistidine as the only labelled amino acid. These findings, taken in conjunction with previous work, suggest that the single active centre of carnitine acetyltransferase contains a histidine residue.


Steroid-producing cells in chick intersexual gonads.


Sperm capacitation after injection of LH or HCG in rabbits.


Drug-induced immunologic tolerance: site of action of cyclophosphamide.


The chemical control of the human environment.


The role of molluscicides in bilharzia control.


Working mother and problem schoolchild.

Working mother and problem schoolchild.


Effects of inbreeding on mortlaity in Fukuoka population.


The growth, reproduction, longevity, and histopathology of rats fed gamma-irradiated carrots.


A 21 year survey of 654 ectopic pregnancies.


The subtle and variable clinical expressions of gluten-induced enteropathy (adult celiac disease, nontropical sprue). An analysis of twenty-one consecutive cases.


Intrauterine growth retardation.

Intrauterine growth retardation.


Sclerosis of the mesenteric arteries of rats. Its relation to longevity and inheritance.


Changes in proportion of thiol to disulphide in acid-soluble nuclear proteins of Echinus during the first cell cycle. 1. DNA synthesis in Echinus esculentus eggs kept at 10 degrees C takes place just after fusion, 0.75-1.5h after fertilization, and at telophase at about 2.67-3.33h after fertilization. 2. An increase in the thiol/thiol+disulphide ratio in acid extracts from washed nuclear fractions of the eggs is found at fusion, at early stages of mitosis and at telophase. When DNA is being synthesized, the relative amount of thiol in the extracts increases. 3. There are at least five thiol-containing histones in the acid extract together with a diffusible thiol peptide containing methyl-lysine and 3-methylhistidine and a thiol-containing acidic protein.


Radioactive peptide 'maps' of the major and minor components of hen's egg ovotransferrin.


Urinary symptoms following hysterectomy.


Mild periodic myasthenia; a case report.


Effects of local steroids on follicular development and atresia in the rabbit.


The influence of ovarian grafts from young donors on the development of transferred ova in aged golden hamsters.


A mixed bag of natural carcinogens.

A mixed bag of natural carcinogens.


Reaction paths to pure 5- and 6-aminofluorescein. Pitfalls encountered in conventional synthesis procedures.


Preparation and reactions of ethyl 4-bromo-2,3-dioxobutyrate 2-arylhydrazones and 4-bromo-2,3-dioxo-1-phenylbutanal 2-arylhydrazones.


Structures of physalin A and physalin B, 13,14-seco-16,24-cyclo-steroids from Physalis alkekengi var. Francheti.


9-Hydroxyprehelminthosporol, a metabolite of Cochliobolus (Helminthosporium) sativus.


Studies on the antibiotic nigericin (polyetherin A).


The biologic half-life of brain-localized antisynapse radioantibodies.


Persistence of "relapse-tendencies" of rats previously made physically dependent on morphine.


Isoantigenic variants: isolation from human diploid cells in culture. Variant human fibroblast substrains, resistant to a cytotoxic human isoantiserum, were isolated from sensitive strains by repeated exposure to isoantiserum and rabbit complement. The resistant phenotype was stable, apparently occurred at low frequency, and was associated with loss of surface isoantigens.


Interferon.

Interferon.


Transient changes in the force-velocity relationship during tetanic contractions of frog sartorius muscles, normal or poisoned with 1-fluoro-2,4-dinitrobenzene.


Relationship of social stress and oral disease.


Experimental observations and mathematical considerations on the mechanism of transport of uric acid across human gastric mucosa.


Pulsatile pressure and flow in the mesenteric vascular bed of the cat.


Micropuncture evaluation of the importance of perivascular pH for the arteriolar diameter on the brain surface.


Intravenous permanent catheterization in cats.


Recording of spinal reflexes evoked by dorsal root stimulation in unanesthetized free moving cats.


Catecholamine excretion by the healthy adult human.


Dialogue: Schizophrenia.

Dialogue: Schizophrenia.


Insect control: alternatives to the use of conventional pesticides.


"Hypersexuality" and behavioral changes in cats caused by administration of p-chlorophenylalanine. The behavior of 26 male cats was systematically observed before, during, and after daily administration of the tryptophan hydroxylase inhibitor, p-chlorophenylalanine. These observations established that "hypersexuality," increased aggression, and perceptual disorientation are sequelae of the chronic administration of the drug in cats.


Chronic occlusion of the superior and inferior mesenteric veins: report of a case.


Evaluation of hepatic regeneration by scintillation scanning, cholangiography and angiography in man.


Some observations of the sedimentation of chicken heart glyceraldehyde 3-phosphate dehydrogenase.


Studies on succinate dehydrogenase. VI. Inhibition by monocarboxylic acids.


In vitro methylation of yeast serine transfer ribonucleic acid.


Amniography (a useful procedure in antenatal care in East Africa).


Cerebral infarction caused by heartworms (Dirofilaria immitis) in a dog.


Canine malignant carotid body tumor.

Canine malignant carotid body tumor.


Eimeria leuckarti infection in the horse.


Lipid storage disease in a Siamese cat.

Lipid storage disease in a Siamese cat.


Nigropallidal encephalomalacia in horses in Colorado.


Sudan grass and sorghum poisoning of horses: a possible lathyrogenic disease.


Report of the AVMA Mastitis Committee.

Report of the AVMA Mastitis Committee.


What is your diagnosis?

What is your diagnosis?


Estimates on the availability of amino acids in soybean oil meal as determined by chick growth assay: methodology as applied to lysine.


Urea and amino acid supplementation of swine diets.


Pancreatic enzyme pattern in rats as affected by dietary soybean flour.


Immune-specific cytotoxic factor formation by small lymphocytes.


Synthetic polynucleotides as restorers of normal antibody-forming capacities in aged mice.


The work-play model: a basis for occupational therapy programming in psychiatry.


Conference on health services for children and youth. Summary of conference recommendations.


Program implications of new knowledge regarding the physical, intellectual, and emotional growth and development and the unmet needs of children and youth.


Examination of the changes in the United States which affect the health of children and youth.


Let's continue to discuss national health insurance.


An important development in public health nursing.


The changing scope of occupational medicine and environmental health.


Chromosome aberrations and malignant disease among A-bomb survivors.


The obstetrician and society.

The obstetrician and society.


The recommended dietary allowances for iron.


Iron deficiency in young women.

Iron deficiency in young women.


Iron nutriture from infancy to adolescence.


Day care for the very young--prime opportunity for primary prevention.


An effective weight control program in a public school system.


Project Head Start: its implications for school health.


Social work in a black community hospital: its implications for the profession.


A health maintenance service for chronically ill patients.


The epidemiology of the QRS axis measurement.


Health and the urban environment. 8. Air pollution, weather, and the common cold.


A report on health education--its relationship to comprehensive health planning at state level: a summary.


Interagency council on drug abuse.

Interagency council on drug abuse.


African trypanosomiasis and its control. 3. The sterile male technique.


Why locked doors?

Why locked doors?


Patients' right to vote.

Patients' right to vote.


NEp related to intake level of baled and pelleted baled alfalfa when fed to lactating dairy cows.


Biological and technical sources of variability in bovine carcass lean tissue composition. I. Technical variation in measurement of potassium, nitrogen and water.


Puberal estrus and ovulation and subsequent estrous cycle patterns in the ewe.


Effect of slaughter weight and castration on carcass characteristics of lambs.


Protein source and level for pregnant gilts: a comparison of corn, opaque-2 corn and corn-soybean meal diets.


Comparisons of simple and complex diets for baby pigs: effect of form of feed and of glucose addition.


Estrual activity in open Rambouillet ewes.


Excretion and tissue distribution of the estrus-synchronizing compound 1-alpha-methylallylthio-carbamoyl-2-methylthiocarbamoylhy-drazine in swine.


Female sex steroid relationships during the estrous cycle of the ewe.


Effect of natural differences in atmospheric temperature on the incidence of first estrus following anestrus in ewes.


Egg transport in beef cattle.

Egg transport in beef cattle.


Effect of energy and protein on estrus, conception rate, growth and milk production of beef females.


Health--whose responsibility?

Health--whose responsibility?


Production, purification, and bioassay of tentoxin.


Growth response of sclerotium rolfsii to the herbicide EPTC in liquid culture and soil.


Mutagenicity of trimethylphosphate in mice. Subtoxic concentrations of trimethyphosphate, administered orally or parenterally to male mice, produced mutagenic effects, dependent on dosage, in the dominant lethal assay.


Acid-base titrations of bovine serum albumin in a water-dioxane mixture.


Research on the carbohydrate-peptide linkage of porcine pancreatic ribonuclease.


Reaction of carbodiimides with protein sulfhydryl groups.


Research on the carbohydrate-peptide linkage of whale pancreatic ribonuclease W2.


The temperature stability of egg yolk high density lipoprotein.


Tropocollagen: depolymerization by L-ascorbic acid.


Characterization of peptides released from human fibrinogen by Arvin.


Characterization of porcine pancreatic isoamylases: separation and amino acid composition.


Alanine as the N-terminal amino acid of glutamate dehydrogenase.


Percentage development of a second infection of Nippostrongylus brasiliensis in rats.


Twinning in the common snapping turtle, Chelydra serpentina.


The development of the human wrist joint during the fetal period.


Associated subvalvular and supravalvular aortic stenosis with aortic valve anomaly.


Contribution of aromatic residue interactions to the stability of myoglobin. V. Enhancement by aromatic compounds of the rate of heat denaturation. Aromatic compounds like chlorpromazine and benzoate and its homologs strongly enhance the rate of heat denaturation of myoglobin. The latter apparently exert their action by complexing with a single kind of site in the hemeprotein. Both charge-transfer and hydrophobic interactions are implicated in complex formation, most probably with the heme moiety.


Evangelism and pollution.

Evangelism and pollution.


A certain symmetry: histocompatibility antigens compared with immunocyte receptors.


Inhibition by hapten of cellular immune responses to a hapten-protein conjugate.


The process of eruption on permanent teeth in twins.


Influence of the adenosinetriphosphoric acid upon the bioelectrical phenomena and the contractility of the rat's myometrium.


Fine structure of cells from a cat with myeloproliferative disorder.


Electron microscopy of bleeder swine platelets.


Naturally occurring aortic medial necrosis in a dog.


Congenital ameloblastic odontoma in a foal.


Development of diagnostic criteria in echographic study of abdominal lesions.


Determination of untreated whole-milk effects on in vitro antibacterial activity. The effect of fresh whole milk without pasteurization or other pretreatment on in vitro antibacterial activity of selected compounds was determined in broth dilution. The milk was collected by hand directly from dairy goats, or by syringe or cannula from bovine quarters showing low bacterial counts. Antibacterial activity was determined in 50% (v/v) milk-broth medium against sensitive mastitis-etiologic strains of Streptococcus agalactiae and Staphylococcus aureus. The indicator salt 2,3,5-triphenyltetrazolium chloride was incorporated in the milk broth medium to determine inoculum growth. Contaminant interference was circumvented through early as well as late readings and comparisons with uninoculated control tubes, with and without the test compounds. Application of the method with more than 75 compounds, including nitrofurans, antibiotics, and other chemicals uncovered marked degrees of milk interference. The method warrants routine use among preliminary screens to relate in vitro with in vivo observations of antimicrobial activity. Similar procedures may be used with serum, skim milk, or mastitis-milk media for separating effects due to protein, lipid, or other elements in product evaluation.


Effects of N2-O2 and CO2-O2 tensions on growth of fungi isolated from damaged flue-cured tobacco. Ten fungi, Aspergillus niger, A. flavus, A. ochraceus, A. ruber, A. repens, A. amstelodami, Alternaria tenuis, Penicillium brevi-compactum, Cladosporium herbarum, and Chaetomium dolicotrichum, were isolated from moldy flue-cured tobacco and grown in various mixtures of N(2)-O(2) or CO(2)-O(2). A 1 to 5% concentration of O(2) in an N(2) atmosphere caused the greatest change in growth of the nine species, and a 10 to 20% concentration of O(2) for A. flavus. All species, except A. amstelodami and A. ruber, grew faster in air than in mixtures containing 10% O(2). High O(2) concentrations generally inhibited furrow production in the mycelial mats. In an atmosphere of 5 to 40% O(2) in the N(2) atmosphere, furrows formed in mycelial mats between 5 and 40% O(2) in the species except for A. ruber, A. repens, and A. amstelodami, which produced none in any concentration. As O(2) decreased below 20%, spore production was progressively decreased, colony color faded to white, and cleistothecia formation was suppressed. In CO(2)-O(2) mixtures radial growth of all species increased with each quantitative decrease of CO(2). All species except A. niger grew faster in air than in 10% CO(2). In contrast to N(2)-O(2) mixtures, the fungi formed furrows, sporulation and cleistothecial formation were suppressed, and colony color changed to white in higher O(2) concentrations.


Spoilage bacteria in canned foods. II. Sulfide spoilage bacteria in canned mushrooms and a versatile medium for the enumeration of Clostridium nigrificans. Clostridium nigrificans was found to be a spoilage organism of canned mushrooms in Taiwan. A modified beef extract tryptone iron medium, both in broth and agar form, was designed for the detection and recovery of the organisms. A procedure of simple plate counting method of C. nigrificans was established.


A trypsin sensitive site for the action of hydrocortisone on calf thymus nuclei.


Characterization of the Semliki Forest virus core and envelope protein.


The reaction of 2'(3')-O-bromoacetyluridine with ribonuclease A.


Estimation of relative risk from individually matched series.


Enhancing effect of proteolytic enzymes on interferon production.


Juxtaposition of atrial appendages associated with normally oriented ventricles and great arteries.


Synthetic steroids. X. Preparation of (3S)- and (3R)-spiro-[5-alpha-cholestane-3,2'-oxiran] and their corresponding 2-alpha-methyl and 2,2-dimethyl analogues.


Chemical modification of trehalose. II. Synthesis of the galacto-analogue of trehalose.


A study on the antifertility action of VIDR-2GD: a constituent isolated from the seeds of Ensete superbum, Cheesm, Musaceae (Banakadali). The antifertility effect of VIDR-2GD, a substance isolated from the seeds of the Musaceae Banakadali, was studied in rabbits, mice, rats, hamsters, and guinea pigs.  In mice and rats, pregnancy was inhibited if the drug was given during the preimplantation period single doses of the drug within 3 days after mating inhibited pregnancy.  In rabbits, pregnancy was prevented in 50-60% of the animals.  The uteri of all the animals receiving the drug were congested and enlarged.  No implantation sites were found.  Rabbit endometrium showed hyperplasial cells.  Uterine stimulation was noted in ovariectomized rats treated with VIDR-2GD.  There was no antagonism to estradiol and only a weak antigonadotropic activity shown.


Investigations on the biosynthesis of steroids and terpenoids. II. Role of 24-methylene derivatives in the biosynthesis of steroids and terpenoids.


Steroidal sulphyr compounds. VII. Pyrolysis and chiroptical properties of 3-alkylsulphinyl-5 alpha-cholestanes.


Caulerpin, a new red pigment from green algae of the genus Caulerpa.


(-) methyl n-tetradeca-trans-2,4,5-trienoate, an allenic ester produced by the male dried bean beetle, Acanthoscelides obtectus (Say).


Benziodazoles: synthesis for bioactivity studies.


Studies related to the chemistry of melanins. VII. Attempts to synthesise hydroxylated bi-indolyls, biphenyls, and indoline-2-carboxylic acid as possible intermediates in the formation of melanins from 3,4-dihydroxyphenethylamine and 3,4-dihydroxyphenylalanine.


Congenital eye defects in the mouse. 3. Lens opacity in NAW-wa-2+--+/Sp.


Virus nucleic acids formed in chick embryo cells infected with Semliki Forest virus.


The fate of influenza virus RNA in cells treated with ultraviolet rays.


Paroxysms of T-wave alterations in the ECG in experimental epilepsy due to foci in the pseudosylvian gyrus.


In vitro effects of isoproterenol and propranolol on human adipose tissue.


Inhibition of cell aggregation by antibodies directed against actomyosin.


Homing of lymph-borne immunoblasts to the gut.


Evidence for polygenic control of plasmodial fusion in Physarum polycephalum.


Killing of cultured mammalian cells by radioactive decay of tritiated thymidine at -196 degrees C.


Chemical nature of chain breaks produced in DNA by x-irradiation in vitro.


The management of stingray injuries of the extremities.


Studies on ovine fascioliasis. I. Observations on the sequential development of the naturally-acquired disease.


Antibody studies in an island cattle population free from brucellosis.


Pantothenic acid deficiency in a commercial herd of pigs.


Salmonella muguga: a new salmonella serotype causing disease in sheep in Tanzania.


An outbreak of whirling disease in rainbow trout.


The use of plastic cuffed endotracheal tubes.


Nucleoside phosphonic acids. 3. A nucleoside phosphonic acid analog of UDP-glucose.


Changes in leucyl- and tyrosyl-tRNA of soybean cotyledons during plant growth.


The interaction of aminoacridines with DNA.


Operative treatment of chronic cystitis by urethrotomy: 10 years of experience.


Urethral-hymenal fusion: a cause of chronic adult female cystitis.


Scalene node excision-biopsy in stages 3 and 4 carcinoma of prostate: background notes and preliminary report.


Adaptation of the Lapides principle for incontinence due to anatomical defects.


The excystment, growth and reproduction of Acanthoparyphium spinulosum Johnston, 1917 (Trematoda) in chicks fed various diets.


Estimation of the molecular weights of the polypeptide chains from the isolated hemagglutinin and neuraminidase subunits of influenza viruses.


The lipids of incomplete influenza virus.


Absence of replication of the DNA of adenovirus type 12 in BHK21 cells.


Cytochemistry and autoradiography of Tipula iridescent virus in Galleria mellonella.


Amniotic fluid analysis in erythroblastosis fetalis. II. Quantitative bilirubin relationships.


Amniotic fluid analysis in erythroblastosis fetalis. 3. The chloroform extract and its relationship to the log delta O.D.450.


Tissue distribution of human chorionic gonadotropin.


Changing educational needs for graduate training of the general surgeon.


Effect of the South Polar Plateau on plasma and urine erythropoietin levels.


The diagnostic cytology of breast carcinoma.


Contribution of estriol to total urinary estrogens during pregnancy.


Studies on the fibrinolytic activity in human semen studied by gel filtration.


Inhibitor of transfer ribonucleic acid methylase in the differentiating slime mold Dictyostelium discoideum. Eight hours after the onset of morphogenesis, an inhibitor of transfer ribonucleic acid methylases appears in differentiating Dictyostelium discoideum. The inhibitor is also present in spores. Fifty per cent of the inhibiting activity is lost upon heating at 100 C for 5 min; it is nondialyzable and sensitive to trypsin.


DNA-mediated transformation of mammalian cells in culture. Increased transforming efficiency following sonication.


Health supervision of young children in Manitoba.


Angioblastic meningiomas; clinicopathologic study of 81 cases.


An integrated obstetrical and newborn training program for interns.


Lactate dehydrogenase in cerebral cyst fluids; total activity and isoenzyme distributions as an index of malignancy.


Virus-specific proteins synthesized in cells infected with RNA+ temperature-sensitive mutants of Sindbis virus. All Sindbis virus temperature-sensitive mutants defective in "late" functions were systematically surveyed by acrylamide-gel electrophoresis for similarities and differences in the intracellular pattern of virus-specific proteins synthesized at the permissive and nonpermissive temperatures. Only cells infected with mutants of complementation group C showed an altered pattern. At the nonpermissive temperature, these mutants failed to induce the synthesis of a polypeptide corresponding to the nucleocapsid protein and instead overproduced a protein of higher molecular weight than either viral structural protein. This defect was shown to be irreversible by the finding that (3)H-leucine incorporated at 41.5 C specifically failed to appear in the nucleocapsid of virions subsequently released at 29 C. Attempts to demonstrate a precursor protein in wild-type infections were inconclusive.


Synthesis, transport, and morphogenesis of type adenovirus capsid proteins. During the period between 20 and 24 hr after infection of KB cells with type 5 adenovirus, at a time when approximately 85% of the proteins made were virus-specific, viral proteins were synthesized on polyribosomes with an average sedimentation coefficient of 200S. The polypeptide chains synthesized during a 1-min period of labeling with (14)C-amino acids had an average sedimentation coefficient of 3.4S in sucrose gradients containing 1% sodium dodecyl sulfate. Within 1 min after completion, the newly made polypeptide chains were released from polyribosomes, and the majority were transported into the nuclei within 6 min. Meanwhile, the immunological reactivity of the newly synthesized proteins also increased rapidly. During the same 6-min interval after synthesis, the single polypeptide chains assembled into multimeric proteins with average sedimentation coefficients of 6S, 9S, and 12S. The 6S and 12S proteins were identified immunologically as the fiber and hexon capsid proteins, respectively. The 9S protein was trypsin-sensitive and appeared to be the precursor of the penton; it was tentatively identified as the penton base. The penton had a sedimentation coefficient of about 10.5S and sedimented with the hexon in sucrose gradients. The concomitant migration of nascent proteins into the nuclei, development of the capsid proteins' immunological reactivity, and morphogenesis of the multimeric capsid proteins suggest that the single polypeptide chains or small complexes were transported into the nuclei where they assembled into mature structural proteins of the virion.


Immunological activity associated with the nucleocapsid and envelope components of an arbovirus. Complement-fixing antigens were detected in the nucleocapsid and envelope of Sindbis virus. Neutralizing antibodies are directed against antigens in the viral envelope.


Leukoplakia of the bladder in females.

Leukoplakia of the bladder in females.


Microscopic comparison of the normal and anencephalic human adrenal gland with emphasis on the transient-zone.


Ultrastructure of human fetal placental membranes in chorioamnionitis and meconium exposure.


A new fetal scalp electrode.

A new fetal scalp electrode.


Intra-uterine transfusion: fetal outcome and complications.


Evidence for a cyclic 32P labeling of deoxyribonucleic acid in irradiated L cells.


Sea-level and high-altitude breeding colonies of Peromyscus maniculatus sonoriensis.


Physical characterization of ribosomes from purified mitochondria of yeast.


Hematological study on a case with cerebellar hemangioblastoma associated with erythrocytosis, with special reference to a erythropoiesis-stimulating activity present in the fluid of the cyst of tumor.


The kinetics of the reaction of N,N-dimethyl-2-phenylaziridinium ion with bovine erythrocyte acetylcholinesterase.


Acetyl-L-alanyl-L-alanyl-L-alanine methyl ester: a new highly specific elastase substrate.


The interaction of ribonuclease with metal ions. 3. Gel filtration studies on the relationship between cupric ion and cytidylic acid binding.


The effects of alkylation of methionyl residues on the properties of horse cytochrome c.


Structural and molecular weight studies on the small copper protein, plastocyanin.


A method for the kinetic analysis of progress curves using horse serum cholinesterase as a model case.


Drug deceptions.

Drug deceptions.


Electron microscopy of human platelet aggregates formed in vitro with and without fibrin production.


Isolated splenic vein occlusion. Review of literature and report of an additional case.


Study of the antibody response to tetracyclines in experimental animals. Preliminary report.


Strategy of malaria eradication questioned.


Cirrhosis of the liver on the increase.

Cirrhosis of the liver on the increase.


Viral hepatitis-a case of transmission by blood transfusion.


Follow-up of incidence of acute upper tract diseases and influenza by means of a computer.


Epidemiological study of amoebas of the limax group in military communities.


Taxonomy and characteristic of the genus Francisella Dorofeev, 1947.


Comparative study of the reactogenicity and effectiveness of different combined vaccines against diphtheria, pertussis and tetanus.


The recovery of Parafilaria bovicola Tubangui, 1934 from an imported Charolais bull.


Feline viral diseases.

Feline viral diseases.


Cesatean section on a thoroughbred mare.


Muscular dystrophy in yearling cattle.

Muscular dystrophy in yearling cattle.


Inherited structural and functional abnormalities in the dog.


Notes on two anomalies in mandrills (Mandrillus sphinx Linn.).


Radiology in portal hypertension.

Radiology in portal hypertension.


Immunogenicity and reactogenicity of live attenuated rubella virus vaccines.


Degradation and structure of porcine calcitonin-1.


Haloacetol phosphates. Potential active-site reagents for aldolase, triose phosphate isomerase, and glycerophosphate dehydrogenase. II. Inactivation of aldolase.


Molecular aggregation of bovine pancreatic ribonuclease induced by substrate.


The preparation of two insoluble forms of the phytohemagglutinin, concanavalin A, and their interactions with polysaccharides and glycoproteins.


Ultrastructural studies of the passage of gold thiomalate across the renal glomerular capillary wall.


A new method of right ventricular outflow reconstruction in corrective surgery for tetralogy of Fallot. The application of the valve-retaining pulmonary artery graft as a patch.


Note on the determination of chymotrypsin and chymotrypsin inhibitor activity using casein.


Spectrophotometric ass for D-ribose-5-phosphateketol-isomerase and for D-ribulose-5-phosphate 3-epimerase.


Immobilization of cholinesterase and urease.


Differences in the ribosomal protein of free and membrane bound polysomes of chick embryo cells.


Embryonic cell surface: electrophoretic mobilities of blastula cells.


The effect of neuraminidase on the rabbit urinary interferon.


Molecular hybridization of RNA from chicken spleen cells after immunization.


Another herbicide on the blacklist.

Another herbicide on the blacklist.


Unabsorbed spot test for infectious mononucleosis.


A pharmacological study of Cyperus rotundus.


An outbreak of Salmonella anatum infection in a hospital in Delhi.


Mesothelioma in a buffalo bullock.

Mesothelioma in a buffalo bullock.


An anthelminthic trial with "Nilverm" against gastro-intestinal nematodes of sheep.


Effect of rinderpest vaccination of spermatogenesis in bulls.


Theileriasis in exotic breeds and a Sahiwal calf.


Pulmonary osteoarthropathy--a case recorded.


Renal diabetes like syndrome in a bullock.


Incidence of "O" strain of foot and mouth disease in Bhutan.


Studies on the gastro-intestinal nematodies of goats (Capra hircus).


High altitude sickness in Kashmir valley cattle at Leh.


Laboratory rearing of fleas.

Laboratory rearing of fleas.


Effects of season and progesterone synchronization on ovulation rate in mature western range ewes.


Effect of fat source and level on utilization of fat by young pigs.


In vitro rumen fermentation of alfalfa hay. Carbon dioxide, methane, VFA and heat production.


A heritable connective tissue disease of dogs and mink resembling Ehlers-Danlos syndrome of man. I. Skin tensile strength properties.


Effects of olfactory bulb resection upon the hair waves in mice.


Effect of perivascular nerve stimulation on ionic concentration ofdog submaxillary saliva.


Maternal effects on behavior and white blood cells of isolated female mice.


Spike initiation of neurosecretory neuron soma in Na deficient or tetrodotoxin medium.


Oxidation of fatty acids by heat treated hemoproteins.


The effect of sonication on lipase activity.


Hereditary fructosemia.

Hereditary fructosemia.


The six "laws" of echoencephalography.

The six "laws" of echoencephalography.


Distal muscle wasting, nephritis, and deafness.


Unruptured aneurysm of the supraclinoid carotid artery. A treatable cause of blindness.


An evaluation of the definition of cerebral death.


Facial pulses in internal carotid artery occlusion.


Spontaneous progressive multifocal leukoencephalopathy.


Regional cerebral blood flow and its autoregulation in patients with transient focal cerebral ischemic attacks.


Nemaline structures in polymyositis. A nonspecific pathological reaction of skeletal muscles.


Homocystinuria. Response to pyridoxine.

Homocystinuria. Response to pyridoxine.


Polymyoclonia with opsoclonus.

Polymyoclonia with opsoclonus.


Radiation therapy in the management of medulloblastoma.


The effect of dried fruit of Solanum sodomaeum on Japanese quail and S.C. White Leghorn cockerel chicks.


Evaluation of FAST Program.

Evaluation of FAST Program.


Lipase in pancreas and intestinal contents of chickens fed heated and raw soybean diets.


Mathematical analysis of energy-nutrient relationships. 1. Protein and energy.


Identity.

Identity.


Twin turkey embryos.

Twin turkey embryos.


A foot pad dermatitis in turkey poults associated with soybean meal.


Antihistomonal activity of ipronidazole in turkeys.


Ipronidazole, an antihistomonal agent, as a turkey growth promotant.


Isolation and structure of trichodiol, a new sesquiterpenoid from Trichothesium roseum.


Toxicity and safety studies with the antihistomonal agent, ipronidazole, in turkeys.


Salmonellae in fish meal plants: relative amounts of contamination at various stages of processing and a method of control. Previous studies have shown that Menhaden fish meal, a common ingredient of animal feeds, is frequently contaminated with salmonellae. Animals that eat contaminated feed may become infected. If they, in turn, are eaten by humans, they may be a means by which salmonellae are introduced into the human population. Epidemiological studies of the fish-meal industry were carried out to determine the sources of salmonellae in fish meal and the factors affecting the persistence and survival of salmonellae during the processing of fish meal. Examination of 190 fish immediately after they came from the Gulf of Mexico revealed no salmonellae, but salmonellae were frequently isolated from samples of fish taken from the boats when they arrived at the plants. Salmonellae were also frequently isolated from dockside water at each of the plants. Approximately 50% of the samples taken in the raw fish processing areas were contaminated with salmonellae. The percentage of samples yielding salmonellae decreased progressively through the various sequences of processing, but more than 15% of the samples taken from the finished products were also positive. Salmonellae were isolated from the raw area of the plant most frequently while the plant was operating and less frequently when the plant was idle, whereas in the processing area of the plant the reverse was true. Salmonellae appeared to survive and multiply in the processing area of the plant while the plant was idle, which resulted in contamination of the first portion of each day's production. Salmonellae in the processed fish meal were reduced to nondetectable levels by reprocessing the first 45 min of each day's production.


Thermal inactivation of Newcastle disease virus. The rate of destruction of hemagglutinins and infectivity of Newcastle disease virus was determined over a temperature range of 37.8 to 60 C. From the calculated values of deltaH and deltaS, it was concluded that inactivation of the hemagglutinating activity and viral infectivity was due to protein denaturation.


Effect of four organophosphorus insecticides on microbial activities in soil. Laboratory tests were conducted with four organophosphorus insecticides, Bay 37289 (O-ethyl O-2,4,5-trichlorophenyl ethylphosphonothioate), diazinon [O,O-diethyl O-(2-isopropyl-4-methyl-6-pyrimidinyl) phosphorothioate], Dursban (O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate), and Zinophos (O,O-diethyl O-2-pyrazinyl phosphorothioate), applied to a sandy loam at rates of 10 and 100 mug/g to determine whether these materials caused any serious effects on microbial activities related to soil fertility. All insecticides showed an effect on fungi and bacteria for the first and second week of incubation, but, subsequently, the populations returned to levels similar to those obtained in the controls. All insecticide applications increased ammonium production, but, in some instances, there appeared to be a slight depression of nitrification. Sulfur oxidation was equal to or better than that obtained with untreated soil in most cases. There was no significant effect on phosphorus mineralization. Oxygen consumption indicated that microbial respiration increased in proportion to the concentration of insecticides, suggesting the possibilities of microbial degradation of the insecticides or their degradation products and of uncoupling oxidative phosphorylation.


Cell-associated nature of cottontail rabbit herpesvirus in vitro. The cottontail rabbit herpesvirus is presently classified in subgroup A of the herpesviruses, whereas the virus is strongly cell associated and belongs in subgroup B.


Variables of the rubella hemagglutination-inhibition test system and their effect on antigen and antibody titers. A systematic study was made of certain variables of the rubella hemagglutination-inhibition (HI) test system and their effect on antigen and antibody titers. Erythrocytes from pigeons and 1-day-old chicks gave similar antigen and antibody titers, but goose erythrocytes gave lower titers. Indicator erythrocytes could be stored in Alsever's solution at 4 C for as long as 2 weeks without losing sensitivity in hemagglutination (HA) and HI tests. Antigen titers varied by eightfold or more in different diluent systems; titers were generally higher at pH 6.2 than at pH 7.2. A diluent without Ca(2+) gave antigen titers as high as those obtained in diluents with added Ca(2+) ions. Antibody titers also varied in different diluent systems. HEPES diluents at pH 6.2 gave higher antibody titers than those obtained in other diluents, but occasional "false-positive" inhibition reactions were seen. Kaolin suspended in borate saline at pH 9.0 effectively removed inhibitor from sera without absorbing specific antibody, but at pH 7.3 it removed various amounts of specific antibody. Antibody titers of sera treated with kaolin at pH 9.0 were similar to those of sera treated with heparin-MnCl(2); treatment with dextran sulfate-CaCl(2) gave lower antibody titers. Antigens varied widely in sensitivity for detecting HI antibody and in the ability to detect diagnostically significant increases in antibody. Sensitivity in detecting antibody was not related to the HA titer of the antigens. Tween-ether-treated antigens gave lower antibody titers but were more reliable than corresponding untreated antigens for serological diagnosis of infection.


Epithelial cysts of the spleen.

Epithelial cysts of the spleen.


More rabies.

More rabies.


Bufadienolides. 4. Reaction of 20-oxo steroids with methoxymethylenetriphenylphosphorane.


Bufadienolides. 8. 12(13--14)abeo skeletal rearrangements.


The nurse in the mental subnormality service.


Further investigations on the immunosuppressive effect of alanosine.


In vitro mitotic activity of unsensitized lymphocytes in the presence of antigen and sensitized lymphocytes.


Sensitivity of human cell strains to interferon.


Applicability of a new synthetic dye-labeled substrate for amylase assay.


Reproductive and lactational performance of rats bred at different ages.


Formation, characterization, and some photochemical properties of a hybrid plant virus.


Association of the face fly, Musca autumnalis, with bison in western North America.


Argas (Persicargas) streptopelia (Ixodoidea: argasidae) on migrating and resident doves in Senegal.