EMG studies of associated movements in a patient with Klippel-Feil syndrome.


Traumatic carotido--cavernous fistulas.

Traumatic carotido--cavernous fistulas.


Experience with fluspirilene (R 6218), a long-acting neuroleptic.


Entrepreneurship and charisma in the medical profession.


Besnier--Boeck--Schaumann's polymyositis. (Muscular sarcoidosis).


Some necessary assumptions of social behavioural science in relation to medicine.


Clinical study of an injectable long-acting neuroleptic agent: fluspirilene (R 6218).


Thai "injection doctors"; antibiotic mediators.


Violation of parental role structure and outcome in schizophrenia. A scored analysis of features in the patient-parent relationship.


Communication and neurosis: semantic components in neurotic verbal communications.


The idiom of demonic possession. A case study.


Variability of respiratory movements in chronic schizophrenics.


Spasmolytic treatment of cerebrovascular diseases.


Intraspinal application of hydrocortisone in radiculitis due to protrusion of intervertebral disk.


Experiences with Adebit in the treatment of the maturity onset diabetes.


Bourdon-Wiersma Stipple test localized cerebral lesions.


Vasalgin in the treatment of vasomotor headaches.


Clinical experiences with Uregyt.

Clinical experiences with Uregyt.


Local application of guanethidine in lagophthalmos.


Observations with Seduxen in oto-rhino-laryngology.


A clinicopharmacological assay of Halidor in disorders of retinal blood supply.


Neonatal shock.

Neonatal shock.


Cockayne's syndrome. Report of a case with normal intelligence.


Effects of orciprenaline (Alupent) in newborn infants of low birth weight.


Symposium: pericardial disease. Introduction.


Electrocardiogram in pericarditis.

Electrocardiogram in pericarditis.


Congenital absence of the left pericardium.


Echocardiographic diagnosis of pericardial effusion.


The hemodynamics of cardiac tamponade and constrictive pericarditis.


Depression of cardiac function by streptomycin and other antimicrobial agents.


Comparative mechanisms of antiarrhythmic agents.


(Galen),+GALEN, Siegel RE: Galen on surgery of the pericardium: an early record of therapy based on anatomic and experimental studies.


Mimics of bacterial endocarditis.

Mimics of bacterial endocarditis.


Coronary artery-coronary sinus fistula.

Coronary artery-coronary sinus fistula.


Management of the cerebral stroke: a case of mistaken fatalism.


Pericardial constriction versus cardiac tamponade.


[Coronary sinus pacing masquerading as interventricular septal perforation by transvenous catheter].


A-V heart block in myocardial infarction.


Wenckebach phenomenon in left bundle branch block.


Hepatic coma: newer pathogenetic and therapeutic factors.


Azathioprine therapy for inflammatory bowel disease. A preliminary  report.


Regional enteritis and its relation to emotional disorders.


Radiological diagnosis of colonic polyps.


Adaptation to uniocular image magnification: modification of the disparity-depth relationship.


Eye-dependent and disparity adaptation to opposite visual-field rotations.


The effect of separation between test and comparison objects on size constancy at various age-levels.


Covert oral behavior as a function of quality of handwriting.


The effect of acoustic confusability on visual search.


Errors in tactile localization.

Errors in tactile localization.


A control for ocular tracking in the demonstration of postretinal visual storage.


Electric hazards in hospitals.

Electric hazards in hospitals.


In vitro studies of human cardiac tissue.


Bupivacaine levels in plasma and cerebrospinal fluid following peridural administration.


The inotropic effect of cyclopropane anesthesia upon the intact dog heart.


The effects of substrates on halothane-depressed isolated human atria.


The effects of hyperthermia and hypothermia on the rate of of induction of anesthesia: calculations using a mathematical model.


Professional liability insurance.

Professional liability insurance.


Modification of the radiometer BMS-3 electrode system to improve thermal stability.


Calibration of gas flowmeters with the bubble burette.


The pediatric suction trap for measurement of blood loss.


A doppler flowmeter for detecting air and other emboli, incorporating a simple method of screening against interference.


Cardiac arrest following succinylcholine in patients with central nervous system injuries.


Paravascular vitreoretinal attachments. Role in retinal tears.


Indirect television ophthalmoscopy.

Indirect television ophthalmoscopy.


Optic nerve hypoplasia. A report of 20 cases.


Primary open-angle glaucoma in adolescents and young adults.


Internuclear ophthalmoplegia, typical and atypical.


Optic disc asymmetry. A sign of ocular hypertension.


Choroidal neovascularization in multifocal (presumed histoplasmin) choroiditis.


Dose response analysis of pilocarpine-induced ocular hypotension.


Cryotherapy of conjunctival papilloma.

Cryotherapy of conjunctival papilloma.


A simple method for widening restricted visual fields.


Retinal lesions in subacute sclerosing panencephalitis.


Marginal myotomy of the medial rectus.

Marginal myotomy of the medial rectus.


Distensibility of the intraocular vascular bed.


Oxygen poisoning of the eyes. Comparison in cyanotic and acyanotic dogs.


Cryptophthalmos.

Cryptophthalmos.


Effects of ocular structures on propagation of ultrasound in the eye.


Blank cartridge injury of the cornea.

Blank cartridge injury of the cornea.


Bilateral orbital myiasis. Report of a case.


Hypothetical halothane hazards.

Hypothetical halothane hazards.


A genetic and karyotype study of complete or incomplete paraxial radial hemimelia in Arizona--implications for genetic counseling.


Some results of research in schizophrenia.


Prognosis in schizophrenia: the role of premorbid, social class, and demographic factors.


Can feelings be enumerated?

Can feelings be enumerated?


CDC's position on in vitro antimicrobial susceptibility testing.


Safe isolation of Coccidioides immitis from clinical specimens.


Intersociety committee methods for ambient air sampling and analysis. Preface.


Tentative method of analysis for iron content of atmospheric particulate matter (bathophenanthroline method).


Tentative method of analysis for suspended particulate matter in the atmosphere: (high-volume method).


Some characteristics of a family.

Some characteristics of a family.


Growth of the Asai child of the Madang district of New Guinea.


Intelligence, family size and socio-economic status.


The social impact of haemophilia.

The social impact of haemophilia.


The clinical laboratory improvement program in New York City. II. Progress after five years of experience.


Tentative method of analysis for nitrate in atmospheric particulate matter (2,4-xylenol method (1)).


Tentative method of analysis for mercaptan content of the atmosphere.


Projections of the growth of the coloured immigrant population of England and Wales.


Protein incorporation by isolated amphibian oocytes. I. Preliminary studies.


Regeneration of larval urodele limbs containing homoplastic transplants.


Heart induction: distribution of active factors in newt endoderm.


The function of the middle ear in lizards: Crotaphytus collaris (iguanidae).


Cell sorting out according to species in aggregates containing mouse and chick embryonic limb mesoblast cells.


Pathology of ther peripheral nerves in leprosy: report of a case. Peripheral nerve trunks were examined from a case of lepromatous leprosy. M. leprae was seen in the nerves in several types of cells. Isolated nerve fibre preparations showed demyelinating lesions due to Schwann cell damage and complete nerve fibre degeneration. The causes of this mixed pattern of damage may involve both a direct effect of the bacilli on nerve fibres and various epiphenomena.


Differences in recruitment order of motor units in phasic and tonic flexion reflex in "spinal man". The recruitment order of motoneurones in muscle contractions has been held to be largely constant and determined by the size of the cell. However, as shown in a previous investigation using electromyographic techniques, the order in which different motor units are activated during voluntary muscle contractions changes in normal human subjects on shifts from phasic to tonic contraction. In order to investigate these two types of activity also in cases in which the cerebral influence on the motoneurone pool is blocked, an analysis was made of the recruitment order in phasic and tonic flexion reflexes in 10 patients with total interruption of the spinal cord. The following four principles were found to apply and presumed to be generally valid for the isolated human spinal cord: (1) in the phasic exteroceptive reflex, the order of recruitment varies despite application of a standardized stimulus; (2) in the tonic reflex, the first unit to be recruited is usually the same even with widely different types of stimuli; (3) a shift from phasic to tonic reflex activation may result in considerable changes in recruitment order; (4) after facilitation by a subliminal long-lasting stimulus, the first unit to be recruited in the phasic reflex is also the first to be recruited in the tonic reflex. It is suggested that a tonic influence on the motoneurone pool is required for the presupposed constancy of the recruitment order.


Peripheral nerve function in chronic liver disease. Peripheral nerve function has been studied in 50 patients with chronic liver disease. An increase in the latency or a reduction in the response amplitude of the evoked sensory potential of the median nerve was detected in 34 of the 50 subjects. This was in striking contrast to the paucity of neurological signs and symptoms suggestive of peripheral nerve damage seen in these patients. There was no evidence to show that alcohol was responsible for the neuropathy. Abnormalities in the excitability changes of sensory nerve during ischaemia were detected in seven of the 16 subjects whose distal sensory latencies were within normal limits. A critical evaluation of the hypotheses which have been postulated to account for the increased resistance of peripheral nerve to inactivation by ischaemia has been made. It is concluded that an increase of the permeability of the periaxonal diffusion barrier to K offers the most acceptable explanation for this phenomenon.


Rate of recovery in motor and sensory fibres of the radial nerve: clinical and electrophysiological aspects. Electromyography and conduction studies in motor and sensory fibres were performed in 58 patients with different types of radial nerve injury. The site of nerve injury was predicted by clinical and electromyographic findings and correlated with changes in conduction, thereby permitting a more exact classification of the type of nerve injury. In patients with Saturday-night palsy, there was considerable slowing of conduction in both motor and sensory fibres across the presumed site of the lesion with return to normality within six to eight weeks. These observations suggest that local demyelination is the cause of nerve palsy. There were changes in sensory conduction even when there was no sensory deficit clinically, with no difference in susceptibility of motor and sensory fibres to ischaemia. In patients with radial nerve palsy secondary to fracture of the humerus, out-growth in motor and sensory fibres was equal and estimated to be about 1 mm per day. When the radial nerve palsy was attributed to traction or mild blunt injury the site of lesion was based on clinical and electromyographic findings. The rate of conduction in motor and sensory fibres was normal, suggesting that axonal damage was the cause of paresis, with sparing of some of the fastest conducting fibres.


Wasting of the hand associated with a cervical rib or band. Nine patients are described with unilateral wasting of the hand muscles associated with elongated C7 transverse processes or with rudimentary cervical ribs. In three patients there was selective wasting of the lateral part of the thenar pad, accompanied by mild weakness of the other hand muscles. In four patients all the hand muscles were wasted, but this was more marked in the lateral part of the thenar pad than elsewhere. In two patients wasting was uniformly distributed throughout the hand. Weakness and wasting in the forearm was only present in four patients and was relatively mild. Sensory loss, when present, affected mainly the inner side of the forearm. Nerve conduction studies revealed no abnormality in the distal part of the median nerve, but some patients had reduced or absent sensory action potentials when the fifth finger was stimulated. In all nine patients a sharp fibrous band was found at operation, which extended from an elongated C7 transverse process or from a rudimentary cervical rib to the region of the scalene tubercle on the first rib. The fibrous band caused angulation of the C8 and T1 roots in five patients, and of the lower trunk of the brachial plexus in three. Pathological changes were frequently visible in affected nerves at the site of angulation. Division of the fibrous band relieved pain and paraesthesiae in eight patients and arrested muscle wasting and weakness in nine patients. There was, however, only slight recovery of power in affected muscles; wasting in the hand appeared to be unchanged after periods of up to eight years.


Acquired hepatocerebral degeneration: report of an atypical case. A case of acquired hepatocerebral degeneration secondary to biliary cirrhosis is described. It differs from the conventional type because of the clinical predominance of cerebellar symptomatology and because the principal neuropathological abnormalities were restricted to the pallidum and to the cerebellum.


Report of 10 operations under local cerebral hypothermia. A method of local cerebral hypothermia with circulatory arrest of one or more of the major vessels of the neck is described. Ten clinical cases have been operated upon, and much has been learned of the operative difficulties including an increased operating time and a high complication rate. There were four post-operative deaths, in one (case 1) there was some evidence that the technique protected the perfused part of the brain from anoxic damage. In case 9 the method itself caused particularly bad operating conditions and eventually the patient died. Case 2 and case 4, like case 1, were patients who were severely ill and who might well have died whatever technique had been used in operating upon them. Of the survivors, one patient (case 3) had a post-operative intracerebral clot which developed during closure and another (case 6) had an intracerebral clot which required removal after 24 hours. Another patient (case 8) had some delay in return to full mental function. In the light of this experience we cannot regard the method in its present form as satisfactory for general use. In our view, its further development requires the discovery of a more effective means of neutralizing the anticoagulants, or doing without anticoagulants altogether. It is also necessary to develop a method of monitoring parts of the brain distant from those directly perfused to give warning of threatened anoxia. Until such time as these problems can be solved we have returned to other procedures but are publishing our results in the hope that other workers will be able to improve upon them.


Subacute necrotizing encephalomyelopathy. Its relationship to central pontine myelinolysis. Clinical and neuropathological features of a case of subacute necrotizing encephalomyelopathy are discussed and compared with the features of central pontine myelinolysis. A hypothesis is offered relating the two diseases to a common aetiological factor.


Uptake and incorporation of amino acids in minute mutants of Drosophila.


Artificial embolization of carotid-cavernous fistula with post-operative patency of internal carotid artery. This report deals with a patient of 86 who developed a carotid-cavernous fistula. Artificial embolization alone was considered the safest treatment for this patient and proved to be adequate. Post-operative preservation of the patency of the internal carotid artery was demonstrated by angiography. We believe this method is particularly appropriate for carotid-cavernous fistulas if it is demonstrated by angiography that the major blood flow of the carotid artery pours into the fistula. A soft-iron clip attached to the muscle can be used for external and forceful guidance of the embolus into the fistula with the help of an electromagnet, hence the patency of the internal carotid artery can be preserved. The embolus should be introduced through the external carotid artery. This is the only case known to us in which patency of the internal carotid artery was post-operatively maintained. We have reviewed 545 reported cases of surgically treated carotid-cavernous fistulas and analysed the results from simple cervical carotid ligation to the more sophisticated methods of artificial embolizations. The results obtained by artificial embolization have been consistently good, while the other techniques have failed in large percentages. Artificial embolization should be used as the primary treatment for carotid-cavernous fistula, since ligation of the internal carotid artery precludes its embolization at a later date.


Abnormal brain scan with subacute extradural haematomas. Four patients are described with proven subacute extradural haematomas, each with an abnormal cerebral scan of diagnostic assistance. A possible mechanism of production of the subacute extradural haematoma is discussed, and appears to be similar to the mechanism involved in the subacute subdural haematoma. The means by which the abnormal scan results in such cases is also examined, from which it appears that non-specific meningeal membrane inflammatory reaction surrounding the haematoma is significant.


Familial centronuclear myopathy.

Familial centronuclear myopathy. The clinical and histological features of two Negro brothers with a centronuclear myopathy are described. They bring to 19 the number of cases now reported with this constellation of physical signs and pathological changes in the muscles. A review of these patients suggests the existence of several different diseases causing this picture, though presumably the underlying biochemical defects are closely related. It is concluded that these myopathies are degenerative rather than due to arrest of foetal muscle maturation.


Head injuries in the 1970's.

Head injuries in the 1970's.


Quantitative immunoelectrophoresis of serum from hospitalized chronic schizophrenic and epileptic patients. Ten serum proteins are measured by quantitative immunoelectrophoresis in 20 chronic schizophrenic and nine epileptic patients. Results from each group are compared with each other and with normal values and significant differences noted. Schizophrenic patients had higher haemopexin levels and epileptic patients had higher α2 group component levels, both compared with normal subjects. Also schizophrenics had higher αPG(p) and α(1)AT levels compared with epileptics.


Interrelationship of respiratory disturbances and changes in blood and CSF gases after severe head injury.


Unilateral and bilateral ECT: a study of memory disturbance and relief from depression. Fifty-one endogenous and reactive female depressives were given a course of either unilateral non-dominant, unilateral dominant, or bilateral ECT. Visual and verbal memory tests and confusion ratings were administered at frequent intervals during the treatment course. Pre-and post-treatment assessments of depression were made. Comparisons of the therapeutic effect of six and of eight ECTs were studied separately. One month after the last ECT the patients were again assessed on the memory and the depression tests. The results of the memory tests indicate that unilateral non-dominant ECT produced least memory disturbance (particularly of a verbal kind) and also less immediate confusion within 40 minutes of each ECT. This observation applies more to the reactive than the endogenous group. Comparisons of the depression tests reveal that unilateral non-dominant ECT is as effective in relieving depression as bilateral ECT, though progress may be less rapid. The observation holds true only for the reactive depressives. Endogenous depressives benefit more from bilateral ECT. Caution is advised against the administration of unilateral dominant ECT, since this group does not respond to treatment as well as the other two groups. Degree of improvement as a whole does not appear to be related to the degree of confusion experienced. The implications of these findings are discussed.


Tryptophan metabolism in depression.

Tryptophan metabolism in depression. Psychiatric patients suffering from endogenous depression and a control group without endogenous depression were given oral loads of L-tryptophan and urinary excretion determined of the tryptophan metabolites on the pyrrolase pathway: kynurenine, 3-hydroxykynurenine, and 3-hydroxyanthranilic acid. Female endogenously depressed subjects excreted significantly more kynurenine and 3-hydroxykynurenine but not the subsequent metabolite 3-hydroxyanthranilic acid than did female control subjects. Variability of excretion of kynurenine and 3-hydroxykynurenine at different times by the same subject was much greater in the endogenously depressed than in the control group. There was no consistent temporal relationship between excretion of metabolites and severity of the depressive illness. The possible significance of the findings in relation to defective tryptophan metabolism in the brain in endogenous depression is commented upon.


Direct measurement of intracranial pressure after operation.


Electrolytes, fluids and energy metabolism in traumatic brain oedema.


Hypothalamic lesions in head injury.

Hypothalamic lesions in head injury.


Spontaneous haemorrhage in the spinal canal.


Regulation of spinal blood flow under physiological and pathological conditions.


Myelopathy in cervical spondylosis: surgical treatment using a posterolateral approach.


Tuberculous osteitis of the skull.

Tuberculous osteitis of the skull.


Hyperbaric oxygenation: a treatment in neurosurgery.


Operative angiography.

Operative angiography.


Echoencephalography with simultaneous A- and B- mode display.


An observation on post-operative spasm and its possible significance.


Temporal factors and the cognitive mediators of stress reaction.


Differences in the motivational significance of heart rate and palmar conductance: two tests of a hypothesis.


Experimenter-expectancy effect as a function of evaluation apprehension.


Distraction and self-esteem effects on attitude change.


Lucerne saponins. 3. Effect of lucerne saponins on larval growth and their detoxification by various sterols.


Determination of copper in foods by atomic absorption spectrophotometry.


Lucerne saponins. II. Purification and fractionation of saponins from lucerne tops and roots and characterisation of the isolated fractions.


Algerian and French rapeseed meals as a protein source for caged laying hens, with observations on their toxic effects.


Factors affecting losses of sugars during acid hydrolysis of polysaccharides.


Alarm for use during ultrafiltration.

Alarm for use during ultrafiltration.


Enhanced blood fibrinolytic activity after direct-current cardioversion.


A simple test tube vibrator.

A simple test tube vibrator.


Pathology of vinyl chloride.

Pathology of vinyl chloride.


Transient psychoses in Africans.

Transient psychoses in Africans.


Battered baby syndrome.

Battered baby syndrome.


A case of "downhill varices".

A case of "downhill varices".


Management of the autistic child.

Management of the autistic child.


The use of oxytocin for induction of labour with special reference to the buccal form and also to a new derivative of buccal oxytocin.


Orthometric view in X-ray pelvimetry.

Orthometric view in X-ray pelvimetry.


Birth control.

Birth control.


Palmomental reflexes in adolescents with behaviour disorders.


Mammalian ecology and epidemiology of zoonoses. Insufficient use has been made of ecological data concerning potential hosts in studies to determine the life cycles of zoonotic parasites and pathogens. Factors such as the geographical distribution of hosts, the altitudes at which they live, their affinities for specific habitats, their vertical distribution within the habitat, and the periodicity of their activities have bearing on the hosts' predisposition to involvement in disease cycles. Diets and feeding habits may determine the likelihood of acquiring infection. Reproductive characteristics determine whether a species is suitable as a reservoir or as an amplifying host. Behavioral factors, such as selection of a particular kind of nest site, may also predispose the involvement of the host with parasites and pathogens. Behavior patterns may determine the maximum population densities of hosts. Estimates of population sizes, of relative abundances of species, and of the involvement of species in disease cycles may be strongly influenced by the collecting and sampling methods that are used and also by the behavioral response of the mammals toward collecting devices, such as traps.


Regeneration of the amputated amphibian limb: retardation by hemicholinium-3. Doses of hemicholinium-3 which partially paralyze the larval salamander profoundly retarded regeneration of the amputated hind limb. The drug also reduced the vascularity and mitotic index of the regenerating tissue. After withdrawal of the drug the rate of regeneration returned to normal. Atropine, in a daily dose of 40 milligrams per kilogram of body weight, did not retard growth. These findings suggest that in the salamander acetylcholine may mediate neurotrophic activity.


Prospects for genetic intervention in man.


Polychlorinated biphenyl: interaction with duck hepatitis virus. Ten-day-old mallard ducklings fed a polychlorinated biphenyl at concentrations of 25, 50, and 100 parts per million for 10 days suffered no apparent clinical intoxication. Five days later these birds were challenged with duck hepatitis virus, and they suffered significantly higher mortality than birds which were not exposed to the polychlorinated biphenyl.


Liver mitochondria from manganese-deficient and pallid mice: function and ultrastructure. Oxidative phosphorylation was studied in isolated liver mitochondria from manganese-deficient mice and in those from a mutant strain, pallid. In mitochondria from manganese-deficient mice, ratios of adenosine triphosphate formed to oxygen consumed were normal, but oxygen uptake was reduced. Electron microscopy of these mitochondria revealed ultrastructural abnormalities including elongation and reorientation of cristae. No biochemical or structural abnormalities were found in mitochondria from pallid mice.


Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man. Delta(9)-Tetrahydrocannabinol (the major active component of marihuana) administered intravenously to normal human volunteers persists in plasma for more than 3 days (t(1/2) = 56 hours). Its metabolites appear in plasma within 10 minutes after administration and persist along with the precursor compound. Delta(9)-Tetrahydrocannabinol is completely metabolized in man, and the radioactive metabolites are excreted in urine and feces for more than 8 days.


Reduced catechol-O-methyltransferase activity in red blood cells of women with primary affective disorder. Red blood cell catechol-O-methyltransferase, histamine-N-methyltransferase, and a methanol-forming enzyme were examined in a number of subjects with mental diseases. Catechol-O-methyltransferase activity was significantly reduced in female subjects with primary affective disorder (depression) as compared to normal women and men, men with primary affective disorder, and schizophrenic men and women. In depressed women, histamine-N-methyltransferase activity was elevated and the methanol-forming enzyme was unchanged.


Intellectual development of children from interracial matings. Interracial offspring of white mothers obtained significantly higher IQ scores at 4 years of age than interracial offspring of Negro mothers, suggesting that environmental factors play an important role in the lower intellectual performance of Negro children.


Treatment of organophosphate poisoning.

Treatment of organophosphate poisoning.


A multiple origin for plastids and mitochondria.


A polymeric reagent for peptide synthesis: O-hydroxynitrophenyl derivative of polystyrene.


Formation of 2-methyl-3-formylfuran from reduced streptomycin.


Nucleosides of branched-chain nitromethyl, cyanomethyl, and aminomethyl sugars.


Diffuse polyposis of the rectum and colon.


Synchronous extirpation in cancer of the rectum.


Comparative effects of diazepam and meperidine as premedication for sigmoidoscopy: a double-blind study.


The diagnosis of partial ileal stenosis before persistent obstruction supervenes.


X-ray diffraction studies of enzymes.

X-ray diffraction studies of enzymes.


Autoradiographic studies on the incorporation rate of 3H thymidine during the S-phase of the mitotic cycle.


A comparison of blind and sighted children on a tactual and performance test.


The effects of time-out on stuttering in a 12 year old boy.


Communication patterns in classes for deaf students.


Parent and pupil perceptions of special classes for emotionally disturbed children.


Method and control of laryngeal EMG electrode placement in man.


Subject positioning and phonation range measures.


Fear arousal, persuasion, and actual versus implied behavioral change: new perspective utilizing a real-life dental hygiene program.


Source evaluation, syllogistic content, and judgments of logical validity by high- and low-dogmatic persons.


To err is humanizing--sometimes: effects of self-esteem, competence, and a pratfall on interpersonal attraction.


Measurement of romantic love.

Measurement of romantic love.


Personality-trait descriptions of differentially liked persons.


Effects of self-esteem, perceived performance, and choice on causal attributions.


The effects of ego identity and partner perception on a Prisoner's Dilemma game.


Attitude measurement by free verbal associations.


Education and susceptibility to the Muller-Lyer Illusion among the Banyankole.


Adolescent suicide and premarital sexual behavior.


Arousal, anxiety, aggression, and attitude change.


Insomnia and the attribution process.

Insomnia and the attribution process.


Use of Doppler ultrasonic flowmeter for angiography.


Subclavian venipuncture: preventable complications; report of two cases.


Prevention of experimental arterial thrombosis and platelet adhesiveness by 2,6-bis-(diethanolamino)-4-piperidinopyrimido-[5,4-d]-pyrimidine (RNA 233).


Intussusception in children.

Intussusception in children.


Renal clearance in man of pharmaceuticals containing radioactive iodine: influence of added carrier iodopyracet or o-iodohippurate.


Antiasthmatic preparations containing corticosteroids available in the United States.


Microtechnique of lymphoblastic transformation test (LTT).


On a new species of Paraphelenchus (Micoletzky, 1922) Micoletzky, 1925 (Nematoda: Paraphelenchidae) from Marathwada, India.


A preliminary note on the occurrence in Turkey of the subalpinus form of the A. maculipennis complex.


Contributions to the knowledge of protozoa found in insects in Andhra Pradesh, India.


Carcinoma of the ampulla of Vater and the terminal bile and pancreatic ducts.


Postoperative changes in fibrinogen and its fractions.


Closure of colonic stomas in patients injured in combat.


Scintiscanning in the diagnosis of rupture of the spleen.


Pancreatic lithiasis.

Pancreatic lithiasis.


Hepatic survival by vascular implantation following interruption of portal venous and hepatic arterial flow.


The use of heparin in the management of pelvic thrombophlebitis.


Submaxillary gland excision.

Submaxillary gland excision.


Effects of nephrectomy and ureteral occlusion on extracellular fluid measurements during shock.


Blood pressure measurement by Doppler ultrasonic detection of arterial wall motion.


Treatment of carcinoma of the breast.

Treatment of carcinoma of the breast.


Use of the Foley catheter for cholangiography during common bile duct exploration.


The value of scintiscans in the diagnosis of splenic abscess.


On-line in vivo measurements of partial pressures of oxygen and carbon dioxide of blood, tissue, and respired air by mass spectrometry.


Roentgenographic evaluation of patients with suspected obstructive jaundice.


Australia antigen and antibody tests in 3,000 Oslo Red Cross Blood Donors.


Cochlear aqueduct in infants.

Cochlear aqueduct in infants.


A function of fantasy in the borderline child.


Locomotor adaptations in the disc-winged bat thyroptera tricolor. I. Functional organization of the adhesive discs.


Standard operating procedures and institutionalization on the psychiatric unit.


Motor activity in brain-injured children.


Children with learning disabilities: conditioning, differentiation, and the effect of distraction.


Decision-making as to type of treatment in a child psychiatry clinic.


Referral patterns among mental health agents in three suburban communities.


Dilemmas in evaluation: implications for administrators of social action programs.


Black studies, Black identity formation and some implications for community psychiatry.


The supply-demand dilemma in community mental health centers.


The effect of general anesthesia, surgery and hospitalization upon the behavior of children.


Effecting interdisciplinary coordination in clinical services to the mentally retarded.


Fluid in the right flank as a roentgenographic sign of acute appendicitis.


Community control: myth or reality?

Community control: myth or reality?


Educating teachers and children in law: an approach to reduced alienation in inner-city schools.


Crohn's disease with predominant involvement of the appendix.


Angiographic findings in diseases of the stomach.


Transbronchial lung biopsy. Laboratory evaluation of a biopsy instrument capable of obtaining specimens suitable for histologic studies.


Production in vitro of Coccidoides immitis spherules and endospores as a diagnostic aid.


Wheelchair-car transfers for quadriplegics.


A glimmer of hope.

A glimmer of hope.


Heroin addiction: the epidemic of the 70's.


Comparison of submaximal cardiovascular step test response to a maximal aerobic performance task.


Improved ellipticity data for several biological membranes.


Estimation of amine oxides in the presence of hepatic microsomes.


Immediate effect of four types of warmup activities upon static flexibility of four selected joints.


The situational attitudes schedule: a morale scale for the chronic medical patient.


A modified colorimetric method based on McCarthy and Paille procedure for estimation of methionine.


Carboxylation of pyruvate by human adipose tissue mitochondria.


An antibody-specific method for the reomoval of an of an endopeptidase from the plant carboxypeptidase, phaseolain.


Use of 1-anilino-8-naphtalene sulfonate to study structural transitions in cell membrane of PMN leucocytes.


A nuclease from animal serum which hydrolyzes double-stranded RNA.


The biosynthesis of a mannolipid that contains a polar metabolite of 15-14C-retinol.


Differential synthesis of ribulosediphosphate carboxylase subunits.


Suppression by ethanol of acetate and hexanoate oxidation studied by nonrecirculating liver perfusion.


Respiratory control associated with cyclic pH transitions induced by N,N1-bis (dichloroacetyl) 1,12-diaminododecane.


Labelling of non C-terminal glutamic acid during C-terminal analysis by the tritiation method when the gamma-glutamyl-peptide linkage is present.


Continued synthesis of non-histone chromosomal proteins during mitosis.


Species-specific interactions between nuclear phosphoproteins and DNA.


Polynucleotide phosphorylase covalently bound to cellulose and its use in the preparation of homopolynucleotides.


A factor in the salt wash of reticulocyte ribosomes that can interact with acetylphenylalanyl-tRNA.


Amino terminal peptides of RNA phage proteins synthesized in the cell free system.


Genealogical study of lipoid proteinosis in South Africa.


Protection from the embryopathic effects of 7-hydroxymethyl-12-methylbenz(a)anthracene by 2-methyl-1,2-bis-(3-pyridyl)1-propanone(metopirone, Ciba) and beta-diethylaminoethyldiphenyl-n-propyl acetate (SKF 525-A). Pretreatment with Metopirone (40 mg.) or SKF 525-A (2 mg./100 g. maternal body weight) protected aganist the embryotoxic and teratogenic actions of7-OHM-12-MBA) (2.5 mg/100 g. maternal body weight) in the Sprague-Dawley rat. At the doses administered SKF-525-A was a more efficient protector than Metopirone. The adrenocorticolytic actions of 7-OHM-12-MBA in the maternal adrenal glands were also prevented by these compounds and a close correlation existed between the degree of protection of the maternal adrenals and of the foetuses. It is suggested that the ultimate embryopathic substance is a metabolite of 7-OHM-12-MBA.


Participation of cysteinyl residues in the structure and function of muscle aldolase. Characterization of mixed disulfide derivatives.


Hereditary hypotrichosis congenita: Marie Unna type.


Hypohidrotic (or anhidrotic) ectodermal dysplasia--an appraisal of diagnostic methods.


Patch test reactions to merthiolate in healthy young subjects.


The patency of sweat ducts in normal-looking skin.


The oxygen consumption of the germinal epithelium in normal and psoriatic skin.


Neutron activation analysis of trace elements in skin. V. Copper and zinc in psoriasis.


Plasma concentrations of griseofulvin in human volunteers.


Oral trisoralen therapy in vitiligo.

Oral trisoralen therapy in vitiligo.


Angiokeratoma of the vulva.

Angiokeratoma of the vulva.


Effect of retinoic acid in psoriasis.

Effect of retinoic acid in psoriasis.


"Visage mauve" (? from imipramine).

"Visage mauve" (? from imipramine).


Hyperkeratosis follicularis et parafollicularis in cutem penetrans (?Kyrle's disease).


Lichen sclerosus et atrophicus with mouth lesions.


A granulomatous reaction to a depot vaccine.


Chronic mucocutaneous candidiasis.

Chronic mucocutaneous candidiasis.


Treatment of phobic patients with antidepressants.


Absorption of vitamin B 12 by the guinea-pig. I. Subcellular localization of vitamin B 12 in the ileal enterocyte during absorption.


Depression and carcinoma.

Depression and carcinoma.


Attempted suicide: nomenclature.

Attempted suicide: nomenclature.


Follow-up of day patients.

Follow-up of day patients.


Phobias and affective illness.

Phobias and affective illness.


First rank symptoms of schizophrenia. I. The frequnncy in schizophrenics on admission to hospital. II. Differences between individual first rank symptoms.


Neurosis and marital interaction. I. Personality and symptoms.


Neurosis and marital interaction. II. Time sharing and social activity.


The spouse of the phobic patient.

The spouse of the phobic patient.


An experimental study of parental castration phantasies.


Hypnoanalysis and analytic psychotherapy: a comparative study.


Basic psychoanalytic concepts. IV. Counter-transference.


Results of systmematic desensitization with phobias re-examined.


Visiting in a female psycho-geriatric ward.


Confidentiality in psychiatry and psychotherapy.


The newer aspects of asthma.

The newer aspects of asthma. These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from transcriptions, they are prepared by Drs. Sydney E. Salmon and Robert W. Schrier, Assistant Professors of Medicine, under the direction of Dr. Lloyd H. Smith, Jr., Professor of Medicine and Chairman of the Department of Medicine.


L-DOPA in Parkinson's Disease.

L-DOPA in Parkinson's Disease.


Production, recognition and treatment of digitalis intoxication. Recent studies dealing with absorption, distribution in the body and fate of digitalis, have provided a basis for better understanding the great variability of individual responses to this drug. When given to patients in sinus rhythm as a cardiotonic agent, digitalis action cannot be accurately assessed nor monitored by appropriate tests; consequently, blind administration of the drug on average dosages inevitably produces digitalis intoxication in a proportion of patients. Clinical signs of digitalis toxicity, factors enhancing its development, its recognition and treatment are summarized here. It is emphasized that digitalis should always be administered as a calculated risk, when benefits are clearly defined, as in overt cardiac failure and in atrial fibrillation associated with excessive ventricular rates. Use for other indications, particularly prophylactic, should be considered experimental and is to be discouraged.


The curative treatment of lymphoma.

The curative treatment of lymphoma.


On the definition and quantitation of health care costs.


Hypokalemia, muscle weakness, and myoglobinuria due to licorice ingestion.


Medicine in the black community.

Medicine in the black community.


State plan for health.

State plan for health.


Umbilical hernia. A retrospective study. One hundred thirty-four cases of umbilical hernia in adults were analyzed as to etiologic and other significant factors. Congenital umbilical hernia is of much higher incidence in black people than white. This is not true of acquired umbilical hernia. On retrospection it was noted that congenital hernias that persisted into adult years had been 1.5 cm or more in diameter in infancy. This indicates that hernia size is a criterion for repair early in life.


RNA distribution in Saprospira grandis: the absence of a highly 2'-O-methylated RNA species.


Extrahepatic factors in the early hypotensive response to bacterial endotoxin.


Changes in specific airway resistance during prolonged breathing of moist air.


The effects of atropine, pralidoxime, and lidocaine on nerve--muscle and respiratory function in organophosphate-treated rabbits.


The effect of local cooling upon spontaneous and evoked electrical activity of cerebral cortex.


Lipids of the intestinal mucosa of normal and essential fatty acid deficient rats.


The effect of loading doses of unlabeled methionine on the oxidative catabolism of 14C-labeled histidine and serine in vivo.


Dynamic lung compliance and the effect of oxygen breathing in patients with chronic bronchitis.


The effect of vasopressin on the reabsorption of sodium, potassium and urea by the renal tubules in man.


A psychiatrist looks at student rebellion.


Assessment of an automatic enzyme reaction rate monitor.


Outpatient gynecological surgery.

Outpatient gynecological surgery.


The interrelationship between ECF volume and ECF anion composition in the regulation of sodium excretion.


Studies of newer drugs used to treat malignancy.


Evaluation of theoretical renal phosphorus threshold as an index of renal phosphorus handling.


Regulation of the enzymes of the beta-ketoadipate pathway in Moraxella. Control of quinate oxidation by protocatechuate.


Polols and turnover rates of nuclear ribosomal RNA in Tetrahymena pyriformis.


Reduction in immunological manifestations of 6-aminopenicillanic acid by treatment with water-insoluble pronase.


The compartmentation of CoA and fatty acid activating enzymes in rat liver mitochondria.


On the active sites of proteases. Cleavage of peptide bonds involving D-alanine residues by carboxypeptidase A.


The conformation of small proteins. The state-diagram of a neurotoxin of Androctonus Australis Hector.


Studies on the metabolism of steroids in the foetus. Biosynthesis of 3-hydroxy-delta 4-C19 steroids in the human foetal liver.


Steroids in germfree and conventional rats. Steroid monosulphates in urine from female rats.


The necessity of an electric potential difference and its use for photophosphorylation in short flash groups.


Effects of x rays on genetic loads in a aage population of Drosophila melanogaster.


Studies on natural populations of Drosophila. X. Effects of disruptive and stabilizing selection on wing length and the correlated response in Drosophila melanogaster.


Concurrent inbreeding and selection in Drosophila pseudoobscura.


Distributive pairing: mechanism for segregation of compound autosomal chromosomes in oocytes of Drosophila melanogaster.


The effects of low temperature and aging on nondisjunction in Drosophila.


Possible nonrandom utilization of X- and Y-bearing sperm in Drosophila melanogaster.


Biochemical analysis of the pinocytotic process. I. Isolation and chemical composition of the lysosomal and the plasma membrane of the rat liver cell.


Effect of polyanions on the antibody formation by spleen cells.


Energy-dependent transport of pteridines into the trypanosomid flagellate, Crithidia fasciculata.


Polymerization behaviour of carboxypeptidase B treated Proteus mirabilis flagellin.


Dq-, Dr and retinoblastoma.

Dq-, Dr and retinoblastoma.


Ossification centres at the elbow joint in Bengali girls.


Cornelia de lange syndrome. Report of a case.


Trichobezoar. Report of a case.

Trichobezoar. Report of a case.


Studies on cellular immunity to human neuroblastoma cells.


Inhibitory effects of anti-tumor platinum compounds on DNA, RNA and protein syntheses in mammalian cells in virtro.


Upper respiratory tract tumors induced in Syrian hamsters by N-methyl-N-nitrosourea.


Possible association of embryonal antigen(s) with several primary 3-methylcholanthrene-induced murine sarcomas.


Genetic deletions at specific loci by polycyclic hydrocarbons in relation to carcinogenesis.


Malignancy, electrophoretic mobilities and sialic acids at the electrokinetic surface of TA3 cells.


Induction of lymphoma in BALB-c mice by Rowson-Parr virus (RPV).


Immunological studies on mouse mammary tumors. V. Chemical analysis of further purified tumor-specific antigen of mouse mammary tumor.


Possible carcinogenic hazards of several tars and of locacorten-tar ointment (spectro-fluorescent investigations and experiments in animals).


Hand-Schueller-Christian disease. Report of a case and review of the literature.


Uneven swelling of the corneal stroma.

Uneven swelling of the corneal stroma.


The effect of exercise on intraocular pressure. I. Human beings.


The effect of exercise on intraocular pressure. II. Rabbits.


Changes in lens fatty acid composition during galactose cataract formation.


Intraocular transport of myoinositol. I. Accumulation in the rabbit ciliary body.


The electrically evoked response of the visual system (EER). 3. Further contribution to the origin of the EER.


Movement of the Stiles-Crawford effect.

Movement of the Stiles-Crawford effect.


Growth of Saccharomycopsis schionning under continuous gassing. Two strains of Saccharomycopsis guttulata, JB-1 and JB-3, isolated from stomach contents of domestic rabbits, were grown under different gas phases, and their growth rates were compared. Strain JB-1 grew exponentially at a maximal growth rate under a continuous gas phase of 15% CO(2), 2% O(2) in nitrogen. High cell yields with low cell granulation were obtained. The growth rates were almost the same between oxygen concentrations of 0.25 and 20% at 15% CO(2). Poor growth and early cell granulation occurred in the absence of oxygen at 15% CO(2). Growth increased at 2% O(2) in direct proportion to the carbon dioxide concentration up to 10 to 15% CO(2). A very high carbon dioxide content (e.g. 98%) was somewhat inhibitory. Cell granulation always occurred during the maximal stationary phase in media at pH 4, but was relatively slight at pH 5.6 or higher. Strain JB-3 responded to various gas phases in a similar manner except that it grew slowly in the absence of oxygen at 15% CO(2) (pH 4). The effect of an optimal gas phase on the growth of strain JB-1 was examined in relation to other environmental conditions. In the presence of 15% CO(2), 2% O(2), this strain grew exponentially in yeast autolysate-Proteose Peptone-glucose medium at 37 C at pH 2, 4, and 5.6 at approximately the same rate; the growth rate was somewhat lower at pH 6.2. Under similar conditions, strain JB-1 grew at 30 C and pH 4 at one-sixth its maximal growth rate. Cell granulation was greatly reduced at this temperature. With adequate CO(2) strain JB-1 also grew at a reduced rate in a yeast autolysate medium previously reported not to support growth. Results indicate that continuous gassing with an optimal gas phase increases the growth rate to the extent that the growth rate surpasses the death rate by a significant margin; as a result, granulated cells can be avoided almost entirely in the log phase.


Mutant analysis and enzyme subunit complementation in bacterial bioluminescence in Photobacterium fischeri. Chemical mutagens were used to obtain mutants deficient in bioluminescence in the marine bacterium Photobacterium fischeri strain MAV. Acridine dyes were effective in the production of dark mutants but not in the production of auxotrophs. These dark mutants were all of one type and appeared to contain lesions blocking the synthesis of luciferase. ICR-191 was especially effective in the production of aldehyde mutants, i.e., dark strains that luminesce when a long-chain aldehyde such as n-decanal is added to them. However, other mutant types were isolated after treatment with ICR-191. N-methyl-N'-nitro-N-nitrosoguanidine induced many bioluminescence-deficient types with respect to both the site of the lesion and the quantitative effect on the luminescent system. We characterized the dark and dim mutants with respect to their response to exogenous decanal, levels of in vivo and in vitro luminescence, and their rates of reversion to wild type. In addition, the luciferases of the mutant strains were examined by subunit complementation. On the basis of these analyses, we identified mutants which synthesize altered luciferase, strains which are deficient in synthesis of luciferase, and aldehyde mutants. The results of analysis of luciferase from the aldehyde mutants and the complementation studies indicate that the lesions in these strains are in the luciferase itself. Results obtained with wild-type cells grown in minimal medium, and aldehyde mutant cells grown either in complete or minimal medium, indicate that a "natural aldehyde factor" is involved in in vivo light emission. These same studies showed that the long-chain aldehyde(s) could only partially substitute for the natural "aldehyde factor." The possibility that the in vivo aldehyde factor is not a long-chain aldehyde is discussed.


Studies on the role of 3-phosphoglycerate dehydrogenase in the regulation of serine biosynthesis in rat liver.


Giant-cell tumor of bone. An analysis of two hundred and eighteen cases.


Rehabilitation of bilateral lower-extremity amputees.


Skeletal growth in achondroplasia.

Skeletal growth in achondroplasia.


A pedigree with anomalies of the little finger in five generations and seventeen individuals.


Electrolyte, water and urea content of dog kidney in acute salt depletion.


Vitallium prosthesis for the olecranon and proximal part of the ulna. Case report with thirteen-year follow-up.


An electrogoniometric study of knee motion in normal gait.


Sensory-nerve-conduction velocity and two-point discrimmination in sutured nerves.


Fracture of neck and shaft of same femur. Report of a case in a child.


The intra-articular deformity in osteochondrosis deformans tibiae.


Malignant hemangioendothelioma of the cervical spine. A case report.


Tibial plateau prosthesis in arthroplasty of the knee.


Surgical management of spastic hip-flexion gait patterns with special reference to iliopsoas recession.


Ambulatory care of lower-extremity fractures.


Reconstruction of the anterior cruciate ligament using the central one-third of the patellar ligament.


Long-bone defects due to missile injury.


Congenital pseudarthrosis of the clavicle.


A modified Bristow operation for anterior recurrent dislocation of the shoulder.


Fractures of the atlas.

Fractures of the atlas.


The biochemical importance of the hypertrophic cartilage cell area to enchondral bone formation.


Experimental attempts to stimulate bone growth.


Hand surgery training.

Hand surgery training.


Intrinsic-extrinsic muscle control of the hand in power grip and precision handling. An electromyographic study.


Zancolli capsulorrhaphy for ulnar claw hand. Appraisal of forty-four cases.


The hand and Apert's syndrome.

The hand and Apert's syndrome.


Palmar-shelf arthroplasty of the wrist in rheumatoid arthritis. A report of nine cases.


Flexor-origin release for pronation-flexion deformity of the forearm and hand in the stroke patient. An evaluation of the early results in eighteen patients.


Carpometacarpal dislocations on the ulnar side of the hand.


Hydrofluoric acid burns of the hand.

Hydrofluoric acid burns of the hand.


Athletic injuries of the proximal interphalangeal joint requiring surgical treatment.


Radial meromelia. The deformity and its treatment.


Fractures of the neck of the talus.

Fractures of the neck of the talus.


A mobile calcified spontaneously amputated ovary.


Foundation for international education in neurological surgery, incorporated.


Rates of formation and absorption of cerebrospinal fluid in mild chronic bovine hypervitaminosis A.


Turbulence in human intracranial saccular aneurysms.


The clinical significance of junctional dilatation of the posterior communicating artery.


Delayed apoplexy following head injury ("traumatische spät-apoplexis").


Cerebral acid-base and gas metabolism in brain injury.


Nonsurgical treatment of chronic subdural hematoma.


Effects of local hypothermia and tissue oxygen studies in experimental paraplegia.


Bilateral carotid vertebrobasilar rete mirabile. Case report.


Radiographic and histologic demonstration of an aneurysm developing on the infundibulum of the posterior communicating artery. Case report.


Brain tissue reaction to some chronically implanted metals.


Trigeminal neuralgia secondary to asymmetry of the petrous bone. Case report.


Ultrasound placement of cardiac tube in ventricular atrial shung. Technical note.


Correspondence: changes in body composition produced by prolonged total starvation and refeeding.


Critique of multicompartmental analysis of calcium kinetics in man based on study of 27 cases.


Renal electrolyte cycles and mechanism of nocturia in primary aldosteronism.


Effect of nicotinic acid administaation on plasma HGH, FFA and glucose in obese subjects and in hypopituitary patients.


Gluco-regulatory hormone response to 2-deoxy-d-glucose infusion in normal subjects at bedrest.


River at risk.

River at risk.


These managers benefit from long-term training program.


Council for postgraduate training.

Council for postgraduate training.


Conversion of glucose to lipid by human adipose tissue in vitro.


Oceans off limits to dumpers.

Oceans off limits to dumpers.


Adipose tissue metabolism of weanling rats after destruction of ventromedial hypothalamic nuclei: effect of hypophysectomy and growth hormone.


1984 the era of young marrieds.

1984 the era of young marrieds.


Interferon stimulated by double stranded RNA.


A ligand exclusion theory of allosteric effects.


Evidence for a new haemoglobin chain (zeta-chain).


Generation of Cherenkov light flashes by cosmic radiation within the eyes of the Apollo astronauts.


Transduction in Mycobacterium smegmatis.


Detection and identification of monoamine oxidase inhibitors in biological samples.


Effect of 6,6'-dithiodinicotinic acid on the dissemination of Ehrlich ascites tumour.


137Cs levels in human adult population in California, 1960-69.


Epidermis and pheromone production in males of the desert locust.


Nitrification and induction of nitrate reductase in nitrogen-deficient algae.


Copper tolerance in the marine fouling alga Ectocarpus siliculosus.


Basic rectangle of the mandible.

Basic rectangle of the mandible.


Misleading units.

Misleading units.


Food for thought.

Food for thought.


Screening of 1,000 patients for inborn errors of metabolism.


The diagnosis of leukemia.

The diagnosis of leukemia.


Correlation of retinal vascular changes with cardiovascular diseases. I. Arteriosclerosis.


Cancer and other disorders related to certain perceptual tests.


Reaction time and temperament type.

Reaction time and temperament type.


Kinesthetic performance by blind and sighted.


Thoughts at random. A running commentary.


Modern views on physiology. XIX. Endocrinology.


Intra-uterine contraception.

Intra-uterine contraception.


Mechanical methods of contraception.

Mechanical methods of contraception.


Sterilization and family planning.

Sterilization and family planning.


Removal of Lippes loop through laparoscope.


Child adoption.

Child adoption.


Oral contraceptives and blood pressure.

Oral contraceptives and blood pressure.


Pruritus ani.

Pruritus ani.


Medicine and the Zulu.

Medicine and the Zulu.


Upper limb ischaemia due to ergotamine tartrate.


Choice of antibiotics for elderly patients.


A service cytology campaign.

A service cytology campaign.


Treatment of depression in general practice. A study of iprindole.


Educational psychology in family medicine.


Vocational training.

Vocational training.


Cataractogenic nnd lathyrogenic effects of N-phenyl-beta-hydrazinopropionitriles and related compounds in rats.


Extinction of avoidance responding through response prevention (flooding).


Contingency model of leadership effectiveness: antecedent and evidential results.


Experiments in overcoming self-deception.


Some experience with the coding and filing of radiological findings.


Effect of contralateral shock stimulation on laterality differences in the two shock threshold.


Lung scintiphotography with 113mIn Fe(OH)3 aggregates.


Influence of some -SH group effectors on the incorporation of mevalonic acid by Pinus pinaster seedlings.


L-glutamate 1-carboxylase and 4-aminobutyrate: 2-oxoglutarate aminotransferase in succulent plants.


Protein metabolism in growing rats. 3. Effects of an early severe protein deprivation and its alleviation by feeding a low protein diet.


Appalachia: focus of health care.

Appalachia: focus of health care.


Temperature-sensitive mutations in Drosophila melanogaster.


Medical education: Carnegie panel urges expansion, acceleration.


Environmental protection in the City of New York. Before ending this account of the status of environmental protection in the nation's largest city, some additional thoughts may be desirable.


Marine sediments: dating by the racemization of amino acids. Isoleucine has been found to undergo a slow racemization reaction in a 5-meter sediment core taken from the Atlantis fracture zone (water depth, 4014 meters; actual location, 30 degrees 15.7'N, 43 degrees 18.9'W). The amount of racemization increases with increasing depth below the sediment-seawater interface. This isoleucine racemization reaction was used to calculate an age of 1.23 million years for the bottom of the core.


Aboriginal trephination: case from southern New England? The skull of a young adult male Amerind from a grave at a coastal site in southern Connecticut bears a largely cicatrized elliptical anomaly near bregma. Some evidence suggests deliberate antemortem trephination of the scraping type. The specimen is of interest since perhaps fewer than twenty human skulls have been advanced as putative cases of trephining by North American aborigines.


Collagen: mobile water content of frozen fibers. From the change in the nuclear magnetic resonance splitting of heavy water in oriented wet collagen fibers at low temperatures, it is estimated that about 0.6 gram of heavy water per gram of collagen does not freeze. This estimate has been confirmed by a measurement of the heat evolved on melting "frozen" wet collagen. The water that does not freeze retains liquid-like mobility even at temperatures as low as -50 degrees C.


Mercury compounds reduce photosynthesis by plankton. Concentrations of organomercurial fungicides as low as 0.1 part per billion in water reduced photosynthesis and growth in laboratory cultures of one species of marine diatom and several natural phytoplankton communities from Florida lakes. The acute toxicity of mercury compounds to phytoplankton is dependent on the chemical nature of the mercury compound and on cell concentrations.


Alcohol dehydrogenase in maize: genetic control of enzyme activity. A gene (Adhr(r)) which controls the activity of alcohol dehydrogenase in the scutellum of maize has been found. This gene is not allelic to the Adh(1) locus, which specifies the charge of the enzyme molecule and hence its migration rate. The two genes are linked and located about 17 crossover units apart. The Adh(r)(N) allele specifies equal activities of both the Adh(1)(S) and Adh(1)(F) products. The Adh(r)(L) allele gives lower activities of the Adh(1)(S) products only and operates in both the cis and the trans configurations.


Ribonuclease-inhibitor system abnormality in dystrophic mouse skeletal muscle. Skeletal muscle extracts from mice with muscular dystrophy contain severalfold higher than normal levels of free alkaline ribonuclease II activity and none of the free ribonuclease inhibitor normally present. This abnormal pattern is not seen in heart or liver extracts from dystrophic mice.


Energy transduction: inhibition of cockroach feeding by naphthoquinone. 1,4-Naphthoquinones inhibit feeding of Periplaneta americana by complexing with sulfhydryl groups of receptor protein in sensory neurons, by oxidizing the sulfhydryl groups, and by being reduced.


Fluorescent labeling of chromosomal DNA: superiority of quinacrine mustard to quinacrine.


Slow synaptic excitation in sympathetic ganglion cells: evidence for synaptic inactivation of potassium conductance. The slow excitatory postsynaptic potential (EPSP) was investigated in frog sympathetic ganglion cells. In contrast to the increased conductance associated with other known EPSP's, during the slow EPSP resting membrane conductance was decreased. Electrical depolarization of the membrane potentiated the slow EPSP, whereas progressive hyperpolarization decreased its size and then reversed it to a hyperpolarizing potential (the opposite of the effect of membrane polarization on other EPSP's). The reversal potential of the slow EPSP was close to the potassium equilibrium potential. We propose that the slow EPSP, in contrast to classical EPSP's, is generated by an inactivation of resting potassium conductance.


Practical guides to prophylaxis and treatment of lung complications.


Value of leukocyte counts in the recognition of mesenteric infarction and strangulation of shorter intestinal lengths: an experimental study.


Pulmonary oxygen toxicity in experimental hemorrhagic shock.


A slow moving pre-beta-lipoprotein band in serum. Report of a diabetic serum subjected to lipoprotein electrophoresis.


Exophthalmos: a study of the etiology.

Exophthalmos: a study of the etiology.


Multiple serum enzyme analyses in chronic alcoholics.


A case of drug-induced (?) pulmonary hypertension.


Hemolysis during acute exercise in patients with aortic ball valve prostheses.


Succinic dehydrogenase activity in skeletal muscle of normals and patients with dystrophia myotonica.


Alpha-fetoprotein in hepatocellular carcinoma with an abnormal electrophoretic alpha-1-fraction.


Poisoning with ethylene glycol monomethyl ether. Report of two cases.


Postnatal development of spinal anterior horn neurones in normal and undernourished rats. A quantitative cytochemical study.


Familial lecithin: cholesterol acyltransferase deficiency. Study of two new patients and their close relatives.


Compassion and competence.

Compassion and competence.


A view of the profession for the graduating dentist.


Anomie and political powerlessness: their relationship to attitudes and knowledge concerning fluoridation.


Effect of the oral environment on the enamel surface.


A lingual vitamin C test. 18. Effect of protein upon vitamin C state.


Unusually large communication between the coronary sinus and the left atrium without associated anomalies. Presentation of a case and review of the literature.


Improving the quality of life.

Improving the quality of life. Unplanned or unwanted pregnancies account for 83% of "lower social group" pregnancies and 15% of "upper social group" pregnancies according to a study by the University of North Carolina and University of Alabama Hospitals and Clinics.  To prevent a 2.5-fold increase in social ills in the U.S. in 25 years, welfare and illegitimate births should be eliminated.  Alabama sterilization law is vague, but the University Hospital Policy permits sterilizations for those with 3 children, 2 cesarean sections, those over 30 years of age with 2 children, or those 21-years-old with 2 illegitimate children.  Abortions are permitted for a patient's total health, if she resides in Jefferson County.


The interaction between certain proteins and hyaluronic acid.


Isometric (dynamometer) stress testing in coronary heart disease.


Isochromosome X.

Isochromosome X.


Diphenylhydantoin fatal hepatic necrosis (a review of literature and report of a case treated with exchange transfusion).


Continuing education in laboratory use for physicians.


Perforating (Sharpey's) fibers of the periodontal ligament and bone.


Handling of iodide, chloride, and pertechnetate by salivary glands and the thyroid gland in man.


Admission inorganic phosphorus correlated with discharge diagnoses and other metabolic profile components.


The teaching hospital and the university: understanding some misunderstandings.


Ovarian pregnancy and the intrauterine device.


Vasopressors in obstetrics. 3. Fetal effects of metaraminol infusion during obstetric spinal hypotension.


Placental transmission and fetal distribution of cyclamate in early human pregnancy.


Induced alteration in the biologic activity of estrogen by DDT.


Naturally occurring antibody to placental protein in human pregnancy. Antibody activity directed against human placental lactogen (HPL) preparations has been found primarily in postpartum patients.  HPL is first detected in maternal serum at about the sixth week of gestation.  10% of women tested showed agglutinating ability against HPL-sensitized cells during pregnancy while more than 80% did post partum.  An explanation for this is that the antigen HPL and its source, the placenta, have disappeared.  Immunochemical studies indicate that the antibody molecule is either IgA or IgM and non-complement-fixing.  The antibody activity of the human anti-HPL is inactivated by 2-mercaptoethanol.  This treatment has been shown to destroy essentially all IgM antibody and around 50% of the IgA activity, but has little effect upon IgG antibody.  Because of the lack of maternal antibody activity against the purest preparation of HPL, it is believed that the antibody is directed against trophoblastic antigens which have not been completely separated from earlier preparations of HPL.


Lack of pathologic clot lysis following gynecologic surgery.


A comparison of the clinical behavior of uterine adenocarcinomas and adenoacanthomas.


Ambiguous genitals due to congenital adrenal hyperplasia. Surgical repair in infancy.


The influence of estradiol-17 beta on cholinesterase activity in the lung.


Carcinoma in situ of the vagina.

Carcinoma in situ of the vagina.


Response of endometrial stromal sarcoma to cyclophosphamide.


Oral contraceptives and amino acid utilization.


Continuance of family planning in a health department clinic.


Circulatory dynamics of pregnancy. IV. Fluid accumulation.


Pseudomyxoma peritonei.

Pseudomyxoma peritonei.


Severe bronchospasm complicating thoracotomy.


Diagnostic value of hematoma in penetrating arterial wounds of the extremities.


Primary hyperparathyroidism in patients with breast carcinoma.


Prolongation of survival in lethally irradiated dogs by pancreatic duct ligation.


Effect of gastrointestinal hormones on salivation in the dog.


Experimental massive intestinal resection. Comparison of surgical measures and spontaneous adaptation.


Problems in 48- to 72-hour preservation of canine kidneys.


Penicillin G and wound healing.

Penicillin G and wound healing.


Postoperative brachial plexus palsy. A sytdy on the mechanism.


Solitary crossed renal ectopia.

Solitary crossed renal ectopia.


Very late wound infection due to retained fecalith.


Surgical management of infections and other complications resulting from drug abuse.


Heterotopic gastric mucosa in the common bile duct.


Gastric heterotopia in the vermiform appendix.


An extreme example of Buerger's disease.


The future and scope of pediatric surgery.


The operating room: a case of need.

The operating room: a case of need.


The prosthetics and orthotics program.

The prosthetics and orthotics program.


Evaluation of synthetic balata for fabricating sockets for below-knee amputation stumps.


A new approach to patient analysis for orthotic prescription. I. The lower extremity.


Amputees and their prostheses.

Amputees and their prostheses.


Projects, programs, and perspectives.

Projects, programs, and perspectives.


Wrist-driven prostheses for a bilateral partial-hand amputee.


Ductus arteriosus. I. Anatomical and histological study of its development during the second half of gestation and its closure after birth. II. Histological study of a few cases of patent ductus arteriosus in infancy.


Fetal and neonatal response to base loading.


The influence of birth weight and nutrition on postnatal growth of rabbits.


A morphometric and biochemical study of fetal and adult rat liver cells, with special reference to energy metabolism.


Analysis of transport in the compartments of the sheep fetus.


A comparison of the growth of white and brown adipose tissue in rabbits reared under controlled conditions.


The concentration of 5-hydroxyindole acetic acid in foetal urine in normal and toxaemic pregnancies.


The association between trabecular rarefaction in the costochondral junction and the idiopathic respiratory distress syndrome.


Factors influencing oxygen consumption in the newborn pig with special reference to feeding.


The incorporation of radioglucose into glycogen in foetal and neonatal rat diaphragm in vitro: the effect of insulin.


Management development programs for hospitals are major investments.


How staff education can reduce waste and cut supply costs.


Towards a general monitoring system for length of stay.


Electric shock protection.

Electric shock protection.


Electrical shock hazards in the hospital environment. Their causes and cures.


The pulmonary surfactant system.

The pulmonary surfactant system.


Two-year end-result study of orthopedic surgery of the lower extremity in the mentally retarded.


Osteotomy of the proximal femur in degenerative arthritis.


Treatment of congenital radial club hand.


Proctalgia fugax: recurrent fulminating coccygodynia. A report of three cases with a review of the literature.


Cervical spine fusions in children.

Cervical spine fusions in children.


Treatment of open tibial fractures by cross-fracture pin fixation.


An unusual fracture of the tibial epiphysis.


Gastric acid secretion by histamine intragastric stimulation in acute hepatitis.


On the absorption of pancreatic enzymes from the intestine in man.


Liver scintillation scanning in the diagnosis of chronic schistosomiasis japonica.


Recurrent perilunar subluxation.

Recurrent perilunar subluxation.


Effect of diazepam on human salivary secretion.


Treatment of hepatic tumours.

Treatment of hepatic tumours.


Management of fractured fingers in the child.


Benign gastric ulcer on the greater curvature and its relationship to ingested medicines.


Cancer of the cervix. Trends in the treatment of uterine carcinoma.


Treatment of malignant nasopharyngeal tumours.


Cancer of the cervix--intracavitary irradiation techniques.


A trial of Ketrax (the laevo-isomer of tetramisole) in the treatment of ascariasis.


The structure of the developing and adult ciliary complex of the rabbit eye: a gross, light, and electron microscopic study.


Bronchial asthma in the tropics. A study of 250 Nigerian patients.


The electrical control system regulating fracture healing in amphibians.


Endocarditis due to a Pasteurella multocida-like organism.


The role of amputation in the treatment of metastatic bone cancer.


Management of metastatic pathological fractures.


Metastatic and primary lesions of bone.

Metastatic and primary lesions of bone.


Cryptococcal meningitis in Mulago Hospital, Kampala.


Radiation treatment of metastatic bone disease.


Medicine, culture and ecology.

Medicine, culture and ecology.


Induction of dominant lethals in mice by TEPA and HEMPA.


Influence of bursectomy on cellular changes in the spleen of immunized chickens. I. An autoradiographic study.


Rattus rattus L. N-, C-terminal amino acids of the main haemoglobin fraction.


Effect of cortisone acetate on plaque-forming cell formation in mice.


Management of malignant disease metastatic to bone by hormonal alterations.


Metastatic disease of the spine.

Metastatic disease of the spine.


Studies on the subcellular site of the biosynthesis of N-glycoloylneuraminic acid in porcine submaxillary gland.


Human protein synthesis. V. The effect of antibiotics on an optimized polyphenylalanine synthesizing cell-free system from human lymphatic tissue.


Heterogeneity of a crystalline human 7S myeloma protein.


Distribution of ammonia-lyases in organelles of castor bean endosperm.


Newer cardiac glycosides and aglycones.

Newer cardiac glycosides and aglycones.


Supplementary glycosides of digitalis.

Supplementary glycosides of digitalis.


Small ring analogs of acetylcholine. Synthesis and absolute configurations of cyclopropane derivatives.


Aromatic amino acid hydroxylase inhibitors. 1. Halogenated phenylalanines.


Inhibition of adrenal phenethanolamine N-methyltransferase by substituted benzimidazoles.


Aralkylaminoguanidines and related compounds.


Azamorphinan and related compounds. 3. Syntheses of 3-hydroxy-N-substituted-9-azamorphinans.


Synthesis and norepinephrine depleting activity of some metaraminol ethers.


Potential antiinflammatory agents. Aralkoxyhydrouracils and aralkoxyhydantoins.


Aminobenzoic acid diuretics. 1. 4-Halogeno-5-sulfamylmetanilic acid derivatives.


Spasmolytics. 3. 3-Tropanyl 2,3-diarylacrylates. A case history of pi-sigma structure-function correlation.


Spasmolytics. II. 3-Tropanyl 2,3-diarylacrylates.


New s-triazine derivatives as depressants for reticuloendothelial hyperfunction induced by bacterial endotoxin.


Synthesis and pharmacological evaluation of alpha,alpha-disubstituted naphthylacetaldehydes.


Synthesis and pharmacological properties of N-derivatives of 5,7,12,13-tetrahydro-6H-dibenz(c,g)azonine.


Specific competitive inhibition of L-asparaginyl transfer ribonucleic acid lygase by beta-aminoamides.


Analogs of the antimalarial 2-bromo-N,N-bis(diethylaminoethyl)-4,5-dimethoxyaniline. 2-Position variations.


Antimalarials. 1. Aminoalkylamino derivatives of 2,3-dihydrofuroquinolines.


Irreversible enzyme inhibitors. CLXXIV. Metabolism of 4-(p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)hydrocinnamido)-o-toluenesulfonyl fluoride (NSC-113423), an active-site-directed irreversible inhibitor of dihydrofolic reductase.


Irreversible enzyme inhibitors. 173. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine.


Irreversible enzyme inhibitors. CLXXV. Irreversible inhibition of purified dihydrofolic reductase.


Irreversible enzyme inhibitors. CLXXVII. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(phenylalkylphenyl)-s-triazines. II.


Irreversible enzyme inhibitors. CLXXVI. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine by ether bridging to a terminal sulfonyl fluoride.


Irreversible enzyme inhibitors. 178. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with a terminal sulfonyl fluoride.


Irreversible enzyme inhibitors. CLXXIX. Active-site-directed irreversible enzyme inhibitors of dihydrofolate reductase from 1-(3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with oxyamide bridges to a terminal sulfonyl fluoride.


Studies on epoxide formation from (2S,3S)-threitol 1,4-bismethanesulfonate. The preparation and biological activity of (2S,3S)-1,2-epoxy-3,4-butanediol 4-methanesulfonate.


Carbamate ester latentiation of physiologically active amines.


Peripheral inhibition of thyroxine by thiohydantoins derived from amino acids.


A molecular orbital study of 3,3',5-trihalothyronine analogs.


Quantitative structure-activity models. Some conditions for application and statistical interpretation.


Structure-activity correlations for anticonvulsant drugs.


On the parabolic relationship between drug potency and hydrophobicity.


Mass spectral analysis in the identification of human metabolites of warfarin.


Isothiazolecarboxaldoximes and methylated derivatives as therapeutic agents in poisoning by organophosphorus compounds.


Perfluoroalkyl carbonyl compounds. 1. Perfluoroaldehyde and perfluorocarboxylic acid derivatives.


Perfluoroalkyl carbonyl compounds. 2. Derivatives of hexafluoroacetone.


Structure-taste relationships of aspartic acid amides.


12-carboxyeudesma-3,11(13)-diene. A novel sesquiterpenic acid with a narrow antifungal spectrum.


A conformational study of beta-phenethanolamine receptor sites. IV. Synthesis of erythro- and threo-3-amino-2-phenyl-2-butanols.


2-Amino-5,6-dihydroxyindan-2-carboxylic acid. A potential hypotensive agent.


Synthesis and pharmacology of a series of substituted 2-aminomethylpyrroles.


A new group of anorexigenic compounds.

A new group of anorexigenic compounds.


Tranquilizing drugs. Carbamates of 4-(4-hydroxypiperidino)-4'-fluorobutyrophenone and analogs.


Some biphenylene derivatives with pharmacophoric side chains.


Hydroxylamine derivatives as potential antimalarial agents. 1. Hydroxamic acids.


Analogs of 1-(4-dimethylaminobenzylidene)indene. Modifications of the amino group.


5'-diazogriseofulvin.


Steroids and related natural products. 63. 17-beta-acetoxy-4-oxa-2-androstene.


Hypocholesteremic agents. 2. Cyclohexane and indan derivatives.


1-dodecylpyridinium dodecyl sulfate.

1-dodecylpyridinium dodecyl sulfate.


SH analog of the estrogen hexestrol.

SH analog of the estrogen hexestrol.


Synthesis of new urethans. p-Ethylsulfonyl- and p-dimethylsulfamoylcarbanilic acid esters.


Synthesis of 5,7-dimethoxyindole.

Synthesis of 5,7-dimethoxyindole.


Dithienylpiperidylthenilates.

Dithienylpiperidylthenilates.


Antifungal activity and geometric isomerism. Anilides of o-coumarinic acid.


Potential antidiabetics. VI. 3-Methyl-4-arylhydrazono-2-isoxazolin-5-ones and 3-methyl-4-arylazo-5-(methyl-phenyl)isoxazoles.


Acetylenics. 1. Aromatic amines containing the acetylenic triple bond.


Pyrolysis of 1-adamantyl azidomethyl ketone.


Relationship between structure of phenothiazines and in vitro cytotoxicity.


The loss of growth vitality of human lymphoid cell lines derived from healthy adults.


Carcinogenicity of diazoacetic ester administered intravenously to rats.


Ultrastructure of the glomerular basement membrane, as visualized by lanthanum.


Base composition and molecular weight of DNA from a frog polyhedral cytoplasmic deoxyribovirus.


A comparative study on the effects of three oral hypoglycemic agents on amino acid decarboxylation.


Increased mast cells in regenerating marrow of normal and hypophysectomized rats.


Antagonism of formaldehyde-induced ocular hypertension by phenylethylamines.


Decreased incidence of restraint-stress induced gastric erosions in rats treated with bovine growth hormone.


A method for removing intravascular clots from embalmed human specimens.


Levels of epinephrine and norepinephrine in blood and tissues of duck, pigeon, turkey, and chicken.


Effects of sodium restriction on renin, norepinephrine, and cation content of cardiovascular tissues of  dogs.


Lipid synthesis from acetate-1-14C by suction blister epidermis and other skin components.


Sodium depletion proteinuria: experimental and electronmicroscopic studies.


Cocaine blockade of the acetylcholine positive inotropic response in ventricular myocardium.


Metabolic effects of human chorionic gonadotropin (HCG) in rats.


Inulin clearance in mice as a standard for radiopharmaceutical bioassay.


Effects of ethanol on glucose utilization in rat brain.


Nuclear volume distribution of phytohemagglutinin-stimulated human lymphocytes.


Relationship between dose size and  dose interval of polyinosinic polycytidylic acid and interferon hyporesponsiveness in mice.


Biosynthesis of tyrocidines by extracts of two strains of Bacillus brevis.


Effect of palmitate on human platelet glycolysis and aggregation.


Reduced bile flow after sulfobromophthalein administration in the rat.


Lens regeneration after mature galactose cataract formation.


Role of gastric acid in aspirin-induced erosive gastritis.


Effect of normal metabolites on the oxygen-hemoglobin equilibrium.


Colony production in vitro by regenerating marrow.


Plasma protein biosynthesis following laparotomy and partial hepatectomy.


Roles of kidney and skeleton in regulation of body fluid fluoride concentrations.


Neoplastic sequelae following subcutaneous implantation of mice with rare earth metals.


Effect of multiple additions of adenine-inosine on the function of stored erythrocytes.


Intra-arterial injections of histamine, serotonin, or bradykinin: a topographic study of vascular leakage.


5-membered heterocyclic compounds: a new class of hypocalcemic agents.


Suppression by ergocornine and iproniazid of carcinogen-induced mammary tumors in rats; effects on serum and pituitary prolactin levels.


Fructose absorption and metabolism by the growing chick.


Strain and substrain differences in the recovery of thymus function after whole-body x-irradiation of mice.


Large scale preparation of liver growth factor for cultivation of nematodes.


Enumeration of virus particles in ultrathin sectioned pellets.


The direct effects of endotoxin on the heart.


Lysine and pipecolic acid metabolism in the domestic fowl.


Uptake and subcellular distribution of norepinephrine in the canine heart following experimental myocardial infarction.


Electrolytes of damaged myocardial mitochondria.


Hepatic acetyl CoA carboxylase, propionyl CoA carboxylase and pyruvate carboxylase activities during embryonic development and growth in chickens.


Allergic encephalomyelitis: passive transfer across major histocompatibility barrier.


Current mortality report. Standard ordinary policyholders, Metropolitan Life Insurance Company. First half 1970 compared with 1969 and 1965-69.


International variations in the motor vehicle hazard.


Cirrhosis of the liver at midlife.

Cirrhosis of the liver at midlife.


Married couples and their dependents.

Married couples and their dependents.


Hospitalization among Metropolitan employees.


Generation life tables.

Generation life tables.


A comparative study of the convulsant effects of strychnos alkaloids.


Fluorimetric determinations by ion pair extraction. 2. Ion pair extraction of a fluorescent secondary amine, protriptyline, in the nanogram range.


Gas chromatography and electron capture detection of benzophenone formed by chromic acid oxidation. 2. Determination of emepronium (Cetiprin), a quaternary ammonium compound in serum.


Gas chromatography and electron capture detection of benzophenone formed by chromic acid oxidation. 3. Applications in the determination of gem-diphenylsubstituted compounds.


Quantitative gas chromatographic determination of picogram quantities of amino and alcoholic compounds by electron capture detection. I. Preparation and properties of the heptafluorobutyryl derivatives.


Studies on the stability and compatibility of drugs in infusion fluids. I. pH and buffer capacity of infusion fluids.


Compounds related to clomethiazole. 3. 4,5-dialkyl-substituted thiazoles, oxazoles and imidazoles.


Intravenous injection of lipid soluble drugs. A preliminary report.


Fibrin-stabilizing factor inhibitors. I. Amides and esters of trans-4-(aminomethyl)cyclohexane carboxylic acid (tranexamic acid).


Particle size and intestinal absorption of acetylsalicylic acid in dogs.


A twin cross-over method for bioassay of insulin using blood glucose levels in mice--a comparison with a rabbit method.


Pitfalls in angiographic diagnosis of malignant renal lesions.


Arteriovenous fistula of the uterine artery. A rare complication of hysterectomy.


Respiratory physiology in annelids.

Respiratory physiology in annelids.


Treatment of the hyperlipidemic states with special emphasis on the place of cholestyramine in therapy.


The influence of venous collecting pressure on measurements of calf blood flow by venous occlusion plethysmography.


Stethoacoustic findings on peripheral arteries and phonoarteriographic records in normal young subjects during the intravenous infusion of adrenalin.


Axillofemoral bypass graft for poor-risk patients.


New directions in research on neurotic and psychosomatic symptoms.


Birdsong and speech development: could there be parallels?


Product inhibition of the fermentative formation of glutamic acid. The addition of penicillin to cells of Corynebacterium glutamicum growing in 5-liter fermentors initiated the excretion of glutamic acid. The rate of glutamate production in fermentors declined continuously with time and reached 75% of the initial rate in 24 hr after penicillin had been added. The addition of glutamate to resting cell suspensions had only a slight effect on sugar utilization but caused a marked decrease in glutamate excretion. It is suggested that the high level of glutamate accumulating in the fermentation broth is responsible for inhibiting its own production.


Mycotoxin from a blue-eye mold of corn.

Mycotoxin from a blue-eye mold of corn. High-moisture yellow dent corn became heavily molded by Penicillium martensii after storage for 6 months at 1 C. Mice ingesting corn molded by P. martensii died within a few days. The toxin was isolated and identified as penicillic acid. Large quantities of the toxin accumulated over a 3-month period on artificially inoculated corn incubated at temperatures between 1 and 15 C. At higher temperatures, the toxin disappeared within 45 days.


Preservation of Borrelia kansas and Plasmodium berghei. Borrelia kansas and Plasmodium berghei have been stored after slow freezing in thioglycollate-glycerol medium for a 6-month period. During this time, 75% or more of the Borrelia remained motile, many intracellular malarial parasites exhibited amoeboid movement, and the growth pattern of both organisms in mice remained unchanged.


Interenvironmental transfer of microorganisms on the exterior surfaces of jet aircraft. The likelihood of microorganisms being transferred to new environments by jet aircraft was investigated. Initial random sampling of the aircraft surface revealed the presence of microorganisms in varying numbers on different aerodynamic surfaces. Bacteria of the genus Bacillus were the most common isolates, comprising approximately one-third of the total organisms found. The most frequently isolated fungi were Cladosporium, Alternaria, Penicillium, and several yeasts. Sampling of surfaces before and immediately after a flight demonstrated that microorganisms were collected during flight in areas protected from the airstream and lost in those areas directly exposed to it. These experiments also showed that the majority of the organisms contaminating the aircraft were acquired from the air at ground level. The placement of microorganisms on the aircraft surface before a flight and determination of their survival after flight indicated that the test organisms were most likely to be transported in the areas protected from the airstream. The organisms showing the best chance of being transferred seem to be the sporeforming bacteria, arthrospore-forming fungi, and some yeasts. All phases of this work showed that microorganisms could be carried by jet aircraft to environments they could not reach by natural means of dispersal.


Spectrophotometric methods for monitoring the microbial transformation of steroids. I. Determination of 9-alpha-fluorohydrocortisone and 9-alpha-fluoro-16-alpha-hydroxyhydrocortisone in fermentation broths. A method has been devised for the determination of 9alpha-fluorohydrocortisone and 9alpha-fluoro-16alpha-hydroxyhydrocortisone in fermentation broths. The method involves extraction of the two steroids from the broth with ethyl acetate, separation through the formation of the water-soluble borate complex of the vicinally hydroxylated steroid, and estimation of each steroid spectrophotometrically.


Cometabolism of m-chlorobenzoate by an Arthrobacter. Twenty isolates representing nine bacterial genera were obtained from enrichment cultures and were shown to cometabolize one or more of 22 substituted benzoates. One of the isolates, an Arthrobacter sp., cometabolized m-chlorobenzoate to a product identified as 4-chlorocatechol by thin-layer chromatography and ultraviolet and infrared spectroscopy. The data indicate that cometabolism by the arthrobacter results from the formation of products by its benzoate-oxiding enzyme system that are not acted upon by the catechol-metabolizing enzymes of the bacterium.


Production of nucleic acid-related substances by fermentation processes. 33. Accumulation of inosine by a mutant of Brevibacterium ammoniagenes. Inosine-producing cultures were found among mutants resistant to 6-mercaptoguanine (6MG) derived from a 5'-inosinic acid (IMP)-producing strain, KY 13102, of Brevibacterium ammoniagenes. Inosine-producing ability was very frequent among the mutants resistant to a low concentration (10 to 50 mug/ml) of 6MG. The accumulation of inosine by strain KY 13714 was stimulated by a low concentration of adenine (25 mg/liter) but was depressed by high levels of adenine. The accumulation by strain KY 13714 was not inhibited by manganese ion but instead was stimulated by its excess, in contrast to IMP accumulation by KY 13102. Addition of hypoxanthine at an early stage of cultivation accelerated inosine accumulation. Furthermore, on addition of hypoxanthine and of a surface-activating agent after 48 hr of cultivation, the simultaneous accumulation of IMP and inosine was observed. A 9.3-mg amount of inosine per ml accumulated after 4 days of cultivation at 30 C. The inosine-producing mutant did not differ from the IMP-producing strain either in 5' purine nucleotide degradation or in IMP formation from hypoxanthine. However, it was found to be completely devoid of purine nucleoside-degrading activity. The conversion of IMP accumulation to inosine can be explained by the lack of nucleosidedegrading activity. The relationship between deficiency of nucleoside-degrading activity and resistance to low levels of 6MG is discussed, and a new mechanism for 6MG resistance is presented.


Methods used to monitor the microbial load of returned lunar material. Methods employed to prepare lunar soil samples and procedures used to detect viable microorganisms are described.


Glycolate dehydrogenase in green algae.

Glycolate dehydrogenase in green algae.


Involvement of sulfhydryl groups in light-dependent transhydrogenase of Rhodopseudomonas spheroides.


Vitamin B12 in the rat kidney. Evidence for an association with lysosomes.


Model selection and parameter evaluation by nonlinear regression, with an application to alpha-chymotrypsin rate data.


Effects of uncouplers of oxidative phosphorylation on the specific conductance of bimolecular lipid membranes.


Distribution of lactate dehydrogenase isozymes in subcellular fractions of rat tissues.


Interaction of androgens with the adrenal mitochondrial cytochrome system. The influence of androgen treatment on the levels of cytochrome in rat adrenal cortical mitochondria and on substrate-induced spectral changes.


In vitro synthesis of particulate glycogen from uridine diphosphate glucose. II. Some studies on the growth process.


In vitro synthesis of particulate glycogen from uridine diphosphate glucose. 3. Some properties of the product synthesized by muscle glycogen synthetase.


Properties of polyriboadenylic acid from rat liver.


Partial purification of RNA polymerase from bovine thymus.


Studies on erythrocruorin. I. Physicochemical properties of earthworm erythrocruorin.


Chemical induction of hepatic porphyria in inbred strains of mice.


Testosterone biosynthesis by rat testis: studies related to an alternate pathway.


Oxidation of cyclopropane fatty acids by Ochromonas danica.


Chlorophyllin a-catalyzed photoreduction of viologen dyes (Krasnovsky reaction).


Incorporation of alanine-14C and leucine-14C into protein of white cells under the influence of acetylcholine.


Developmental patterns of LDH isozymes in fast and slow muscles of the rat.


Biosynthetic relationships among very long chain hydrocarbons, ketones, and secondary alcohols and the noninvolvement of alkenyl glyceryl ethers in their biosynthesis.


Substrate-binding properties of firefly luciferase. II. ATP-binding site.


Effect of pressure on sedimentation velocity patterns. II. Myosin at pH 8.3.


Effects of pressure on sedimentation velocity patterns. I. Alpha chymotrypsin at pH 6.2.


Effect of pressure on sedimentation velocity patterns. 3. Concentration-dependent hypersharpening in myosin at pH 8.3.


Oxidation of thiocyanate to cyanide and sulfate by the lactoperoxidase-hydrogen peroxide system.


Lipid-protein interactions in mitochondria. I. Conditions affecting binding of phospholipids to lipid-depleted mitochondria.


Lipid-protein interactions in mitochondria. II. On the nature and biochemical significance of the interaction between phospholipids and lipid-depleted mitochondria.


The influence of inorganic phosphate and phosphorylated hexoses on the activity of pyruvate kinase.


Tissue distribution and subcellular localization of H3-prostaglandin E1 in rats and dogs.


Stimulation of barbiturate metabolism by spironolactone in mice.


The antagonism of local anesthetic induced convulsions by the benzodiazepine derivative diazepam.


Mode of action of 4-(m-Chlorophenylcarbamoyloxy)-2-butynyltrimethylammonium chloride, McN-A-343, on isolated intestine of several species.


Effect on newborn rats of perinatal exposure to phenobarbital.


Caudal dopamine and stereotype behaviour of cats.


Clinical signs and development of tolerance to thiopental.


Amino acids of brain and gamma-hydroxybutyrate-induced depression.


The effect of ouabain on calcium exchange in renal tubules of the rabbit.


Influence of anticoagulants and autonomic drugs on plasma free fatty acids and glucose.


Influence of epinephrine infusion on the blood flow rate in the rat.


Cardiovascular effects of 2-pyridine aldoxime methylchloride (pralidoxime and blood pressure).


Mode of action of N-methyl beta-phenylethylamine in the goat.


The ability of various nicotinic agents to release acetylcholine from synaptic vesicles.


Tissue calcium losses following reserpine administration in rabbits.


Isolation of enzyme-bound peptide intermediates in tyrocidine biosynthesis.


Biosynthetic studies with carbon-13: mollisin.


Mass spectrometry of perdeuterated molecules of biological origin. Fatty acid esters from Scenedesmus obliquus.


Occurrence of 2-aminoethylphosphonic acid in human brain.


Extrinsic Cotton effect and immunological properties of the p-azobenzenearsonate hapten attached to a helical amino acid copolymer.


Studies on the carbohydrate portion of membrane-located mouse H-2 alloantigens.


Effect of illumination on the membrane permeability of rod photoreceptor discs.


Studies on the fermentation of D-alpha-lysine. Purification and properties of an adenosine triphosphate regulated B 12-coenzyme-dependent D-alpha-lysine mutase complex from Clostridium sticklandii.


Near-ultraviolet absorption bands of tryptophan. Studies using indole and 3-methylindole as models.


Thermodynamic pK, delta H-o, delta S-o, and delta Cp-o values for proton dissociation from several purines and their nucleosides in aqueous solution.


Effect of conformation on isotopic exchange in synthetic polypeptides.


Kinetics of the oxidation of ferrocyanide by horseradish peroxidase compounds I and II.


Enzymic and immunochemical properties of lysozyme. Evaluation of several amino group reversible blocking reagents.


Subunit homologies in bacterial luciferases.


Isolation and characterization of rabbit muscle triose phosphate isomerase.


Isolation of two distinct collagens from chick cartilage.


Properties of colchicine binding protein from chick embryo brain. Interactions with vinca alkaloids and podophyllotoxin.


Sulfoxide formation from methionine or its sulfide analogs during aerobic oxidation of sulfite.


Extracellular 2-acetamido-2-deoxy-D-galacto-D-galactan from Aspergillus nidulans.


Protein components of erythrocyte membranes from different animal species.


Some aspects of the uptake and conversion of 35S-sulfate to the organic form in plants.


Carcinoid of the rectum.

Carcinoid of the rectum.


Carcinoid syndrome.

Carcinoid syndrome.


Introduction.

Introduction.


L-dopa and amantadine for Parkinsonism.

L-dopa and amantadine for Parkinsonism.


The pharmacologic and biochemical nature of carcinoid tumors.


Clindamycin (Dalacin C).

Clindamycin (Dalacin C).


Long-acting fluphenazine injections.

Long-acting fluphenazine injections.


Restriction of ototoxic effect of streptomycin.


Taste sensitivity in chronic throat infections.


The "silent" neoplasm.

The "silent" neoplasm.


Photocoagulation of diabetic retinopathy (a rationale).


Increase in pediatric asthma hospital admissions.


Management of chalazion in prevention of malignant growth.


A clinical study of phacolytic glaucoma.


Serum proteins in diabetic retinopathy.

Serum proteins in diabetic retinopathy.


Fight For Sight Awards. 294,593 dollars for 1969.


Pitfalls in otoplasty.

Pitfalls in otoplasty.


Migraine, giddiness and cerebral dehydration.