Repeat variation of electrocardiogram, blood pressure, and blood cholesterol within one hour and six months. The intraindividual repeat variation of the conventional 12-lead electrocardiogram, of blood pressure, and of blood cholesterol was determined in 27 middle-aged healthy men with an interval of one hour and six months. In 7 of 17 analysed electrocardiographic items the variation within six months was significantly greater than that within one hour; in 10 items, the variation was not significantly different. Blood pressure varied as much within one hour as within six months, while the intraindividual variation of serum cholesterol was significantly greater for the six-month period. The intraindividual variation, expressed as the coefficient of variation, was greater for the electrocardiogram than for either blood pressure or cholesterol. There were large differences between various electrocardiographic items in the repeat variation. There was high intraclass correlation of most items analysed, but no significant covariation between electrocardiographic item vs. blood pressure or cholesterol.


Extent of possible rehabilitation of service personnel with ischaemic heart disease. Sixty unselected survivors from ischaemic heart disease, all male service personnel, were treated, within 1 to 6 months of recovery from the acute episode, by promotion of physical activity, correction of coronary risk factors, and routine use of nicoumalone and prenylamine lactate. The results showed that this approach was conducive to more rewarding rehabilitation than was obtained in 89 patients who, in the past, were on conventional treatment based on advice regarding weight, diet, and physical and mental activity. Thus within 1 to 30 months of treatment by this approach, out of 60 patients, 12 were fit for medical category A active service duties in operational areas in any part of the world in any terrain, including altitudes between 10,000 and 18,000 feet, 30 were fit for medical category B service duties in non-operational communication zones in any part of the world including altitudes below 10,000 feet, and 17 were fit for medical category C sedentary duties in non-operational areas in India only. One patient, who initially recovered from congestive heart failure, died while in a state of temporary unfitness for service. No patient was released from service on account of ischaemic heart disease. Against this, by the conventional approach, out of 89 patients, 81 were fit for medical category C sedentary duties in non-operational areas in India only, 4 were released from service, and 4 died.


The pathogenesis of endomyocardial fibrosis: the question of 5-hydroxytryptamine. Thirty Nigerians with established endomyocardial fibrosis were studied. Basal serum 5-hydroxytryptamine levels were estimated on three different occasions at one-monthly intervals. Twentyfour hours before each estimation, dietary staples containing 5-hydroxytryptamine were excluded from the diet. Subsequently the patients were fed on a plantain diet and serum levels of 5-hydroxytryptamine were estimated at one- and three-hour intervals after plantain ingestion. 5-hydroxytryptamine was assayed on the fundal strip of rat's stomach. These values were compared with those obtained in an earlier study on healthy Nigerians. It was observed that, as in healthy Nigerians, no significant increase in serum 5-hydroxytryptamine levels occurred in these patients after plantain ingestion. The difference between endomyocardial fibrosis and carcinoid heart disease is underlined and it is emphasized that no correlation exists between the incidence of endomyocardial fibrosis and the high content of 5-hydroxytryptamine in the local dietary staples.


Value of reference tracings in diagnosis and assessment of constrictive epi- and pericarditis. Reference tracings are of great value in the diagnosis and assessment of constrictive pericarditis. The Q-h interval in the jugular venous pulse tracing is strongly correlated with the mean right atrial pressure (r=0.91). The left ventricular ejection time, the Q-A2 interval, and the Q-h interval are independent during atrial fibrillation from the preceding diastolic filling interval. This differentiates constrictive pericarditis from valvular heart disease. Cases with haemodynamically significant constrictive epicarditis are characterized by a rapid evolution, absence of pericardial calcification and absence of an early diastolic filling sound, a dominant a wave in the jugular venous pulse tracing, and a high early diastolic ventricular pressure. The haemodynamic behaviour is similar to that found in cases with myocardial fibrosis.


Correlation of degree of left ventricular volume overload with clinical course in aortic and mitral regurgitation. The results of left ventricular volume studies using biplane angiocardiography are described in 20 patients with mitral regurgitation and in 27 patients with aortic regurgitation. In both lesions, a regurgitant fraction of over 60 per cent was likely to be associated with severe symptoms and most patients in this group required operation. End-diastolic volumes were higher in patients with aortic regurgitation and were tolerated with fewer symptoms than in the group with mitral regurgitation. Most (19/21) of the patients with low ejection fractions (<0.60) had either rheumatic valvular lesions or had had potassium citrate as a cardioplegic drug at previous heart operations. The possible myocardial effects of these factors are discussed. Left ventricular volume studies have proved useful in the assessment of valvular regurgitation by quantitating regurgitant flow and giving a measure of the relative importance of valvular and myocardial disease.


Late systolic click in non-obstructive cardiomyopathy. Two patients with seriously impaired left ventricular function, abnormal left ventricular conduction on the electrocardiogram, mitral regurgitation, and a very late systolic click are reported. Idiopathic non-obstructive cardiomyopathy seemed to be the cause of the left ventricular dysfunction in both cases. The mitral valve was anatomically normal at the time of operation in one patient, except for dilatation of the annulus, and the mitral regurgitation appeared to be secondary to left ventricular failure. The very late timing of the mitral systolic clicks in these two patients may be related to a large left ventricular end-diastolic volume and impaired left ventricular function, or to an abnormal sequence of excitation of the left ventricle. The timing of the late systolic click in these patients is in contrast to that in patients with mid systolic clicks, hearts of normal size, and little cardiac disability.


Phasic aortic flow velocity in patients with pulsus alternans. Phasic aortic flow velocity was recorded in two patients with pulsus alternans using a flow velocity probe connected to a Doppler ultrasonic flowmeter system. The variations in beat-to-beat peak velocity paralleled the variations in arterial and ventricular systolic pressures. This study provides direct evidence that stroke volume varies during this abnormal haemodynamic status. It is conceivable, though not proved in this study, that this phenomenon may be secondary to alternation between large and small end-diastolic fibre length.


Preclinical diabetes mellitus in precocious myocardial infarction. A series of 45 patients who had a myocardial infarction before the age of 45 years has been studied and investigated for alterations of glucose tolerance, as shown by standard and prednisolone-primed glucose tolerance tests. Abnormal responses to standard glucose tolerance tests and prednisolone-primed glucose tolerance tests were obtained in 75.5 per cent of patients with myocardial infarction, compared with 8.8 per cent of controls.Sex, hypertension, obesity, and a positive family history did not affect the abnormalities of glucose tolerance. Various views concerning these abnormalities in glucose metabolism are discussed.


Anomalous origin of left coronary artery from pulmonary artery associated with an aorto-pulmonary septal defect. Aorto-pulmonary septal defects and anomalous origins of left coronary artery from pulmonary artery are briefly discussed. The difficulties of diagnosis and surgical correction are put forward in a situation when the left coronary artery arises from a site of high pressure and saturation, such as the pulmonary artery in the presence of an aorto-pulmonary septal defect, as in the case described.


Cor triatrium dexter.

Cor triatrium dexter. A case of cor triatrium dexter is described in which the patient had been independently assessed in two cardiological centres as having a form of Ebstein's anomaly. The differential diognosis is discussed.


Giant peaked upright T waves in cerebrovascular accident. Tall upright T waves, with a maximal T/QRS ratio (in lead V4) of 1.32, appeared in a 52-year-old patient after a cerebral haemorrhage which was confirmed at necropsy. Hyperkalaemia during life and endocardial or myocardial damage were not found.


Information retrieval.

Information retrieval.


Writing for a journal.

Writing for a journal.


Steps in the planning of a research project.


The organization of postgraduate medical education within the health service.


The place of the Faculty of Anaesthetists in postgraduate education.


Careers in anaesthesia in the United Kingdom.


On the practice of anaesthesia in the United States.


On the practice of anaesthesia in Canada.


On the practice of anaesthesia in Australasia.


On the practice of anaesthesia in Sweden.


On the practice of anaesthesia in the Republic of South Africa.


The effect of dosage and premedication on the action of ketamine.


Modification by the baroreceptors of responses in sympathetic nerves evoked by stimulation of cutaneous nerves in the dog.


Effect of hyperbaric oxygen on nerve tissue.


Clinical observations and sputum rheology.


Interaction between halothane and hydrostatic pressure.


Comparison of oxygen content of blood measured directly with values derived from measurements of oxygen tension.


A system for the determination of liquid-gas partition coefficients using gas chromatography.


Changes in serum potassium following suxamethonium in the uraemic rat.


Electroencephalographic investigation of awareness during anaesthesia.


Syphilis screening using the multi-channel blood-grouping machine.


Inoculation pinta in chimpanzees.

Inoculation pinta in chimpanzees.


Review of hospitalized cases of general paralysis of the insane.


Six-city study of treatment of gonorrhoea in men using single oral doses of 1.5 or 3 g. tetracycline hydrochloride.


Appendicitis in infancy.

Appendicitis in infancy.


Examining schoolchildren.

Examining schoolchildren.


Holiday cholera.

Holiday cholera.


Traps in tuberculosis.

Traps in tuberculosis.


Glucose and insulin secretory response patterns following diet and tolazamide therapy in diabetes. Glucose and insulin secretory response patterns during glucose tolerance tests were determined in 28 maturity-onset diabetics, and the sequential effects of diet and a sulphonylurea, tolazamide, were assessed. Untreated diabetics showed hyperglycaemia, increased serum immunoreactive insulin response patterns, delayed insulin release, and relative insulin deficiency. Diet alone partially corrected the hyperglycaemia and serum immunoreactive insulin response but had no effect on the delayed insulin release or relative insulin deficiency. Tolazamide plus diet restored all values towards normal. The net effect of maintenance tolazamide therapy was to (1) restore the insulin secretory response pattern to normal, (2) reduce total pancreatic insulin output, and (3) improve the efficiency of insulin secretion. The results suggest that there is a rational basis for the use of sulphonylurea in all maturity-onset diabetics, including patients with mild carbohydrate intolerance and those who are apparently controlled by diet alone.


Hepatitis-associated antigen and antibody in haemodialysis patients and staff. The screening of a dialysis population for the presence of hepatitis-associated antigen (H.A. antigen) has proved to be of value in locating a probable source of infection and in terminating an outbreak of hepatitis by early detection of H.A. antigen positive patients and staff.


Foot skin ischaemia in atherosclerotic peripheral vascular disease. Hyperbaric oxygen and the vasodilating effect of tolazoline hydrochloride were used to investigate atherosclerotic ischaemia of the skin of the foot. Ischaemic feet were divided into two subgroups each with a foot blood flow significantly higher than normal and significantly different from each other. The high blood flow in the ischaemic feet appears to have been an attempt to meet a tissue oxygen need. In some instances this need seems to have been satisfied but without obvious benefit to the ischaemic or anoxic skin. It is suggested that a local rather than a regional blood flow insufficiency is the cause of skin lesions in peripheral vascular disease.


Retroperitoneal fibrosis causing localized portal hypertension.


Gastrointestinal replacement solution.

Gastrointestinal replacement solution. The mean sodium concentration of 61 gastrointestinal aspirations in peritonitis was 103 mEq/l. (S.D. 16.66), of 16 aspirations in vagotomy 88 mEq/l. (S.D. 19.49), of 12 aspirations in perforated duodenal ulcer 81 mEq/l. (S.D. 19.49), and of 15 aspirations in intestinal obstruction 89 mEq/l. (S.D. 19.49). The mean potassium concentrations were 9, 9.9, 13, and 8.8 mEq/l. respectively, and the mean chloride concentrations 122, 131, 125, and 112 mEq/l. respectively. It is suggested that a gastrointestinal replacement solution should contain 100 mEq of sodium, 12 mEq of potassium, and 122 mEq of chloride per litre; 50 g. of dextrose or 100 g. of fructose may be added to provide energy.


Vitamin B12 excretion in patients with various skin diseases. The excretion in the urine of (58)Co after an oral dose of (58)Co vitamin B(12) given together with intrinsic factor has been found to be reduced in a number of patients with psoriasis, eczema, and other less common dermatoses. There is a correlation between the abnormality and the extent of the rash. A reduced glomerular filtration rate was found in a few of the patients in whom it was measured, and this must have been responsible, at least in part, for the reduced excretion of vitamin B(12) in these patients, but abnormal vitamin B(12) excretion also occurred in the absence of impaired renal function. Our evidence is insufficient to show whether malabsorption or increased tissue utilization of vitamin B(12) was the explanation in other cases. Certainly a number of patients had steatorrhoea, and in these it is most likely that malabsorption was the major factor. In patients without steatorrhoea a lone malabsorption of vitamin B(12) cannot be excluded. A decreased serum concentration of vitamin B(12) was found in only one of the patients.


Multiple sclerosis in the African.

Multiple sclerosis in the African.


Tricuspid valve replacement in rheumatic heart disease. The diagnosis of tricuspid valve disease is often difficult; the best treatment is not yet established. Twenty patients had tricuspid valve replacements at St. Thomas's Hospital as part of multiple valve replacement procedures. The hospital mortality was 25%, most deaths being due to a low cardiac output causing hepatorenal failure. Preoperative cardiac cachexia had a fatal outcome in all cases. Except in two instances, surviving patients returned to a satisfactory level of activity.


Clofibrate.

Clofibrate.


Thrombosis and carcinoma of the prostate.


Ascertainment and prevention of genetic disease. A genetic register system has been developed for the ascertainment and prevention of genetic disease. Its potential value is illustrated with data collected from 478 families with serious genetic disorders which had been seen during the past five years. Of these 249 were referred specifically for genetic counselling, autosomal dominant disorders accounting for the largest group of families with individuals at high risk of becoming affected. Of 717 individuals at high risk of having affected children (or carrier daughters in the case of X-linked recessive disorders), only 101 were referred specifically for counselling. Many were referred only after the birth of an affected child which might otherwise have been prevented. A genetic register system linked to practitioner, hospital, and health department records could be a valuable means of preventing genetic disease.


Thromboembolic disease and the pill.

Thromboembolic disease and the pill.


Vagotomy and peptic ulcer.

Vagotomy and peptic ulcer.


Pulmonary tuberculosis follow-up.

Pulmonary tuberculosis follow-up.


Driving and epilepsy.

Driving and epilepsy.


Paraquat toxicity.

Paraquat toxicity.


Undiagnosed abdominal pain.

Undiagnosed abdominal pain.


Breast-milk jaundice.

Breast-milk jaundice.


Blood-tests for paternity.

Blood-tests for paternity.


Acute epiglottitis.

Acute epiglottitis.


Radioactive Patients.

Radioactive Patients.


Role of the Nurse.

Role of the Nurse.


Osteoporosis and fluoride therapy.

Osteoporosis and fluoride therapy.


Life in flats.

Life in flats.


Living it up with Concorde.

Living it up with Concorde.


Parotid swellings.

Parotid swellings.


Noise in the laboratory.

Noise in the laboratory.


Lateral subcutaneous internal sphincterotomy in treatment of anal fissure. One hundred and three patients with anal fissures have been treated by lateral internal sphincterotomy performed by a subcutaneous myotomy technique, and 99 have been successfully followed up for from 3 to 24 months (mean 11 months). The operation was free from significant complications, apart from slight reactionary bleeding in one case and a perianal abscess in another. The fissure persisted or recurred in three cases, in one of which a further lateral sphincterotomy was performed, with cure. Various minor defects of anal continence were noted in 12 cases. These results have been found to be superior to those obtained previously in the same surgical unit with open posterior internal sphincterotomy and simple sphincter-stretching respectively in the treatment of anal fissure. The most reliable and satisfactory operation at present available for this condition seems, therefore, to be lateral subcutaneous internal sphincterotomy.


Inspiratory obstruction.

Inspiratory obstruction. Obstructing lesions of the trachea and larynx which cause a predominantly inspiratory obstruction can be satisfactorily diagnosed by measuring both F.I.V.(1) and F.E.V.(1). Chronic airways obstruction involving intrathoracic airways produces a much lower F.E.V.(1)/F.I.V.(1) percentage than normal, whereas obstruction to larynx and trachea causes a raised F.E.V.(1)/F.I.V.(1) percentage. If flow-volume measurements are not available the F.E.V.(1)/F.I.V.(1) percentage should provide a simple and useful method for diagnosis of upper airways obstruction.In one of the patients reported a predominantly inspiratory obstruction caused CO(2) retention. In patients with airways obstruction the correlation between Pco(2) and F.I.V.(1) was found to be the same as between Pco(2) and F.E.V.(1). This suggests that respiratory failure can be caused by either inspiratory or expiratory airways obstruction and that neither is of greater importance in producing CO(2) retention.


Puffing frequency and nicotine intake in cigarette smokers. The smoking behaviour of 36 subjects smoking cigarettes with different filter retention efficiencies for nicotine was studied. Subjects were observed while performing various tasks on a driving simulator and also during a resting period after the tasks. Smokers of cigarettes with high-retention filters took more frequent puffs and obtained nearly the same amount of nicotine as smokers of cigarettes with low-retention filters, both while performing the tasks and during the resting period. Smokers of both types of cigarettes took significantly more puffs and obtained more nicotine per unit time during the resting period than during the tasks. The results are compatible with the possibility that smokers automatically adjust the nicotine dose obtained from a cigarette to some "optimum" level which may vary with different activities.


Cancer of the bladder in patients treated with chlornaphazine. Two patients treated for Hodgkin's disease with chlornaphazine developed cancer of the bladder five and six years after treatment with the drug had been stopped.


Development of vascular lesions in insulin-treated animals fed a normal diet. Experiments were undertaken to study the role of hyperinsulinism in the pathogenesis of atheroma. Chickens injected with long-acting insulin for 19 weeks developed lipid containing lesions in their aortas. This provides further evidence in favour of the hypothesis that insulin and atheroma are causally related.


Thrombectomy for renal venous thrombosis in infant of diabetic mother.


Neurological manifestations of hereditary haemorrhagic telangiectasis.


Radiology in the management of asymptomatic renal space-occupying lesions.


Immunization schedules.

Immunization schedules.


Is screening for cancer worth while? Results from a well-woman clinic for cancer detection. 1,768 women were screened for breast and cervical cancer in the year May 1968 to April 1969. Clinical examination followed the completion of a simple questionary. Investigations included thermography and mammography of the breast and cytology of the cervical and vaginal smears. Breast cancer was detected in 15 patients (0.85% or 8.5 per 1,000) and none was aware of any abnormality though 13 of the tumours were clinically palpable. Carcinoma in situ of the cervix was found in a further eight (0.45% or 4.5 per 1,000).


Liaison of a county health department medical officer with a group of general practitioners in Hampshire. A pilot scheme was set up in Hampshire in January 1970, in which a local health authority doctor was "attached" to a group of general practitioners to carry out developmental assessment on infants and young children. Older pre-school children are also seen when necessary, and in all cases possible future educational requirements are considered. Such a scheme reduces duplication of work, increases mutual understanding between general practitioners and local health authority doctors, and helps to make full use of the limited resources of medical manpower.


Radio and telephone system for multiple channel transmission of E.C.G.s.


Nomogram for calculating mass of alcohol in different beverages.


Remissions in diabetes mellitus.

Remissions in diabetes mellitus.


Home or hospital?

Home or hospital?


Soccer supporters' wrist.

Soccer supporters' wrist.


Influenza vaccination.

Influenza vaccination.


Thromboembolic complications in myelomatosis.


Surgery for duodenal ulcer.

Surgery for duodenal ulcer.


Antimacrophagic properties of antilymphocytic serum.


Cardiac arrest and bone cement.

Cardiac arrest and bone cement.


Prophylaxis of deep venous thrombosis.

Prophylaxis of deep venous thrombosis.


Sleeping pills.

Sleeping pills.


Anaemia and psychomotor function.

Anaemia and psychomotor function.


Testamentary capacity in Scotland.

Testamentary capacity in Scotland.


Court of protection in action.

Court of protection in action.


Mediastinoscopy under local anesthesia. A valuable diagnostic technique. Mediastinoscopy is an important, new endoscopic diagnostic technique. The simplicity of the technique and low morbidity and mortality associated with the procedure when carried out under local anesthesia suggest that in many instances mediastinoscopy for direct visualization and excision of biopsy specimens may replace diagnostic thoracotomy in many cases.


"Shock lung".

"Shock lung". These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California Medical Center, San Francisco. Taken from transcriptions, they are prepared by Drs. Martin J. Cline and Hibbard E. Williams, Associate Professors of Medicine, under the direction of Dr. Lloyd H. Smith, Jr., Professor of Medicine and Chairman of the Department of Medicine.


Presumed transmission of salmonella by sigmoidoscope.


Etiologic diagnosis of lower respiratory tract infections. Decision as to the role of infection in lower respiratory tract disease requires examination by culture of specimens known to be derived from the infra-laryngeal respiratory tract. Methods that involve the upper respiratory tract in collection of specimens entail the hazard of contamination by microbiota resident in the upper respiratory tract.The extrapulmonary approaches of cutting-needle biopsy and needle aspiration of intrathoracic disease have not been impressively productive of etiologic diagnosis of infections. While open-chest surgical biopsy has been a highly effective means to diagnosis, this approach does have special requirements in facilities and technical skills.Percutaneous transtracheal aspiration of tracheo-broncho-pulmonary secretions-exudates has been productive of useful information. Because of inherent simplicity and safety, transtracheal aspiration should precede resort to more demanding, difficult, dangerous procedures.


Relevance today and tomorrow in medical education. A forum with a purpose. Students of today question the relevance of much of their formal education. In medical schools the concern is particularly with the relevance of the educational experience to the professional commitment in modern society. To engender discussion of the subject, California Medicine in its January issue printed eight essays by authors known to have keen interest in the subject. Readers in California and elsewhere are invited to take part in a continuation of the forum in succeeding issues. The following are contributions selected from those received to date. Others will be published in the months ahead. At an appropriate time the material will be collated and, if feasible, the distillate will be prepared in the form of a statement. If you have thoughts on the subject, just address them to the editors of California Medicine, 693 Sutter Street, San Francisco, California, 94102. Keep your essays short, please.


Bacteria in sputum--contaminants or culprits?


The preventability of birth defects.

The preventability of birth defects.


The concept of mainstream medicine for all Californians. Fifth Progress Report of Committee on Role of Medicine in Society. I. This Fifth Progress Report is to be printed in three parts in California Medicine. Following the appearance of Part III the report will be bound in a pamphlet which may be ordered at $1 a copy from 693 Sutter Publications, Inc., 693 Sutter Street, San Francisco, California 94102.


Professional corporations. Tax questions still raised.


Medicine and human values.

Medicine and human values.


CMA's certificate in continuing medical education.


Pyrimidine type enzyme inhibitors. I. Design of active pyrimidines of virostatic value.


Lymphocyte transformation in contact sensitivity.


Induction of delayed hypersensitivity by dinitrophenylated lymphocytes.


Variations in the properties of rabbit antibodies during prolonged immunization by various routes with serum albumin in Freund's complete adjuvant.


Haemagglutination-inhibition studies of the combining sites of anti-peptide antibodies in mice and rats.


Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. 3. Electron microscopic study.


Corrugated arteries. Correlation of clinical and histopathologic findings.


Aneurysms in autologous venous patches used for arterial reconstruction. A late complication.


Exercise testing in the evaluation of patients undergoint direct arterial surgery.


24-Hour urinary luteinizing hormone (LW) and follicle stimulating hormone (FSH) excretion in normal children.


Measurement of aldosterone secretion rate by radio-immunoassay.


Treatment of experimental hypercalcemia with oral phosphate.


Studies of the protein binding of testosterone in plasma in disorders of thyroid function: effect of therapy.


An adult phenotypic male with a 46,XX chromosome complement.


Hyponatremia due to sulfonylurea compounds.


Acetylation of cortisol by a human astrocytoma.


Influence of testosterone binding to serum proteins on aromatization by enzymes of human placental microsomes.


The ionic behavior of fatty acids solubilized by bile salts.


Heights and weights of adolescent girls in a city of northern Iran.


Stimulation of release of thyroid iodine by serum of thyroid-immunized rabbits.


Delayed management of facial fractures.

Delayed management of facial fractures.


Skin temperature, blood flow, and venous occlusion.


Clinical, biochemical and pathological studies of long term "clofibrate" therapy.


Circulation in the capillaries of the basilar membrane.


Interesting broncho-pulmonary problems of early life.


Hemodynamic effects of isoproterenol and nor-epinephrine. An experimental study of cardiac output and regional blood flows.


A new sewing ring for experimental mitral valve prosthesis allowing rapid changing of valves in vivo.


Ten-years surgical treatment of cyanotic congenital heart diseases.


Iatrogenic arteriovenous fistula: an unusual complication of cardiac catheterisation.


Experimental research concerning the relationship of focal medianecrosis to arteriosclerosis.


Tympanoplasty with the interior fascial graft technique and ossicular reconstruction.


A para meniscal traumatic arterio-venous aneurysm.


The pathogenesis of orbital complications in acute sinusitis.


Electrochemical creation of autobiological lining for thrombosis prevention in prostheses of cardiovascular system.


Mesothelioma of the pericardium.

Mesothelioma of the pericardium.


Exercise left ventricular end-diastolic pressure. A physiologic indicator of coronary artery disease.


Antacid-induced phosphorus depletion and repletion.


Pulmonary function in thoracic scoliosis, before and after corrective surgery.


Sporotrichosis. A report of 21 cases.

Sporotrichosis. A report of 21 cases.


Long-term effects of diskography in dogs.


Intra-aortic balloon pumping: limitations and advantages.


Retropharyngeal hematomas.

Retropharyngeal hematomas.


Treatment of arteria lusoria sinistra in the adult.


The weight-bearing cast in fractures of the tibia.


Alcohol-related highway accidents. A hospital survey.


So your patient has a high alkaline phosphatase.


Studies on X-chromosome aneuploidy at the Faribault State School.


Vascular disease of the spinal cord.

Vascular disease of the spinal cord.


Omnipen (ampicillin) for prophylaxis. Prior to oral surgery.


Cerebral infarctions.

Cerebral infarctions.


Diabetes detection and education center. A regional resource for the practicing physician.


Folic acid deficiency. Multiple complications.


Hepatorenal toxicity of tetracycline.

Hepatorenal toxicity of tetracycline.


Acid-base balance abnormalities in respiratory therapy.


Neoplasms of the brachial plexus.

Neoplasms of the brachial plexus.


Curbstone consultation. Reconstructive surgery in arterial occlusive disease of the lower extremities.


Internal injuries associated with fractures.


Injuries to the larynx and trachea. Automobile crash.


Acute alcoholic withdrawal syndrome.

Acute alcoholic withdrawal syndrome.


Thyroid suppression testing.

Thyroid suppression testing.


Hypothermia in uremia.

Hypothermia in uremia.


A new approach to the study of psychogenic disturbances.


Biochemical defects in two types of human hepatic porphyria.


Efficacy of pre-1962 drugs.

Efficacy of pre-1962 drugs.


Bone marrow: more questions than answers.


Orphenadrine and propoxyphene.

Orphenadrine and propoxyphene.


Treatment of acromegaly.

Treatment of acromegaly.


Home transfusion for patients with hemophilia A.


Psychiatric complications of open-heart surgery. A re-examination.


Reserpine in thyrotoxic crisis.

Reserpine in thyrotoxic crisis.


Renal hypertension due to hydronephrosis with normal plasma renin activity.


The status of forensic pathology in the United States.


Members of the Board.

Members of the Board.


A little freedom for the hemophiliac.

A little freedom for the hemophiliac.


Levodopa and tests for urinary glucose.

Levodopa and tests for urinary glucose.


Murmurs in coronary-artery disease.

Murmurs in coronary-artery disease.


Serum squalene and methyl sterols.

Serum squalene and methyl sterols.


Lead poisoning.

Lead poisoning.


Contaminated humidifiers.

Contaminated humidifiers.


Genetic aspects of misbehavior.

Genetic aspects of misbehavior.


University surgeon at work.

University surgeon at work.


"Unapproved" subspecialties.

"Unapproved" subspecialties.


Obligatory general-practice years.

Obligatory general-practice years.


Natural foods.

Natural foods.


Health of the Vietnamese people.

Health of the Vietnamese people.


Pain, emotion and a rationale for therapy.


Current concepts of the pain process.

Current concepts of the pain process.


The general surgeon's approach to abdominal pain of obscure origin.


Disability evaluation and physical therapeutics in patients with chronic pains.


Thoracic and abdominal pain originating in the vertebral axis. Some aspects of physical diagnosis.


Use of drugs in control of chronic pain.


Abortion request and post-operative response. A Washington community survey.


Some perspectives in biomedical engineering and artificial organs.


"Relationships between community hospitals and medical schools".


Tracheal stenosis. A review of four cases.


Angiocardiography.

Angiocardiography.


Bilateral noncalculous ureteropelvic obstruction. Report of a case associated with anuria.


Cardiac disease in pregnancy.

Cardiac disease in pregnancy.


Why a pediatric convalescence hospital?

Why a pediatric convalescence hospital?


Enzyme electrophoresis and speciation of Schistosoma intermediate hosts.


Preliminary studies on the karyotypes of five species of Glossina.


Inhibition of cardiac effects of noradrenaline by eleven indole alkaloids, two azepinoindoles, quinidine, quindonium, and propranolol.


2-methyl-2-tert. butyl-ketolactone, an anti-adhesive drug preventing platelet and red cell aggregation.


The effect of piperazine on toad and earthworm muscle membrane potentials.


The duration of action of antinociceptive agents ad determined in mice using the arachidonic acid writhing test.


The "staircase maze" and the "simple staircase" in the analysis of the psychopharmacological action of CNS depressants.


The influence of chloroquine upon the metabolism of collagen in rat.


Effect of electric shock on rats' activity in familiar and unfamiliar environments.


Stationary visual texture and the estimation of slant angle.


Forgetting of an operant response: physostigmine-produced increases in escape latency in rats as a function of time of injection.


Four effects of exogenous insulin on food intake.


Visual orientation during lateral head tilt when upright and supine.


Reproduction and recognition in short-term visual memory.


Effect of prlonged tilt on visual orientation.


Consonant recognition with two levels of decision complexity.


Lateral dominance in the perception of size and of pain.


Reaction times and response competition between the right and left hands.


The effect of shock duration and intensity on the ingestion of food of varying palatability.


An aspect of perceptual organization involved in reading typed and handwritten words.


The effect of stimulus relevance on the cortical evoked potentials.


A priority system for the inspection of x-ray facilities.


Disposal of radioactive wastes from U.S. Naval nuclear-powered ships and their support facilities, 1969.


II. Water.

II. Water.


3. Air and deposition. Radioactivity in airborne particulates and precipitation.


IV. Other data.

IV. Other data.


Microscopic observation of cell-wall modifications in Staphylococcus aureus cells treated with chloramphenicol or phenethyl alcohol.


Immuno-electrophoretic study of secretion in cystic oviducts of female and intersexual chicks.


Effects of amino acid analogs on growth and toxin of Staphylococcus aureus.


Atypical myeloma proteins with the property of aggregation.


Change in colloidal gold clearance in rats treated with SKF 525-A.


The structure and function of the cell envelope of gram-negative bacteria.


The spread of cancer.

The spread of cancer.


The folate status of alcoholics.

The folate status of alcoholics.


Acute otitis media in children. A medical social study from general practice.


Nematode damage to brain of striped dolphin, Lagenorhynchus obliquidens.


Hymenolepis nana and H. microstoma: oncospheral hook orientation.


Trypanosoma cruzi-like parasites in the slow loris (Nycticebus coucang) from Malaysia.


Toxicity of Millipore filter detergent to diffusion chamber cultures.


The development and distribution of antilymphocytic and other antibodies in horses immunized with human lymphoid antigens.


Exporting: technical problems involved in marketing and selling overseas.


Innervation of iridic melanophores.

Innervation of iridic melanophores.


Infectiveness of the histidine dependent mutant of Rhizobium trifolii.


Investigation on the variability of pathogenicity of Newcastle disease virus (NDV). VII. Influence of air deficiency of chick embryos.


Response-contingent CS termination in the extinction of avoidance learning.


Automated group desensitization--a follow-up report.


The psychophysiological basis of introversion-extraversion.


Sex differences and generalization of anxiety reduction with automated desensitization and minimal therapist interaction.


The effects of blocking an instrumental avoidance response: fear reduction or enhancement?


The relationship between social comments as unconditioned stimuli and fear responding.


The alleviation of test anxiety by systematic desensitization.


Comparison of rates of elution of 24Na+ from the mucosal and serosal sides of the toad bladder.


Reaction rate profiles in membrane systems.


A model for sugar transport across red cell membranes without carriers.


Compartmentation and exchange of potassium in the toad bladder.


Inhibition of water and solute permeability in human red cells.


Gas chromatographic determination of the configuration of alanine and serine in staphylococcal cell walls.


Results of a behavior modification training program for parents and teachers.


Hormone action at the membrane level. II. The binding of epinephrine and glucagon to the rat liver plasma membrane.


Effects of persantin on deoxycytidine transport by murine leukemia cells.


Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.


Small angle x-ray diffraction of myelin membrane: lack of effect of deuterium oxide on myelin.


Acute long bone diaphyseal infarcts in sickle cell disease.


Involvement of the duodenum by metastases from tumours of the genital tract.


The Rutherford Morison pouch; a characteristic appearance on abdominal radiographs.


Bladder neck stenosis--the value of descending cysto-urethrography in the demonstration of this complication of inflammatory urethral stricture.


An assessment of intra-uterine foetal visualisation.


How safe is diagnostic sonar?

How safe is diagnostic sonar?


Osteopetrosis with spondylolysis--four cases in one family.


Traumatic mesenteric arteriovenous fistula.


The radiological features of congenital porphyria.


A case of eight-toed foot.

A case of eight-toed foot.


Traumatic intrahepatic arterioportal fistula.


Klyxray; a new preparation for excessive emptying of the colon.


A method of copying x-ray films.

A method of copying x-ray films.


Coeliac disease.

Coeliac disease.


Correlation of subjective side effects with plasma concentrations of nortriptyline. Plasma levels of tricyclic antidepressant drugs vary considerably between individuals receiving the same amount of drug. The bearing of this variation on the occurrence of subjective side effects was investigated in 40 psychiatric inpatients with depressive disorders. Plasma levels were determined before and during four weeks of treatment with nortriptyline 50 mg. three times a day and patients were rated for subjective side effects, the assessors being unaware of the plasma levels of the drug.Plasma levels varied widely between individual patients, but in any given patient the plasma level tended to be constant over a period of time. The side effects of nortriptyline diminished significantly with time and were in most cases absent during the fourth week of treatment. There was a significant positive correlation between plasma level of nortriptyline and subjective side effects.The steady-state plasma level of a drug which is metabolized is usually a more important determinant for its effect than dosage, since it reflects the amount of drug available for biological action. Very high plasma levels of nortriptyline should presumably be avoided, since there is no evidence that they are needed for therapeutic effect and they are potentially harmful.


Postoperative pulmonary atelectasis and collapse, and its prophylaxis with intravenous bicarbonate. Of 181 patients undergoing major abdominal surgery 116 developed chest complications associated with a metabolic acidosis, low Pco2, depressed tidal volume, increased respiratory rate, but no increase in minute volume. In a matched group of 116 patients given intravenous bicarbonate postoperatively only 15 developed chest complications. This suggests that respiratory physiological dead space decreases in patients with pulmonary collapse and atelectasis following surgery. Acidotic respiration proved inefficient in the postoperative period, and intravenous bicarbonate had a very pronounced effect on the tidal and minute volumes of acidotic patients with pulmonary collapse and atelectasis.


Intestinal absorption of calcium-47 after treatment with oral oestrogen-gestogens in senile osteoporosis. Intestinal absorption of radiocalcium was measured in 15 postmenopausal women with osteoporosis before and after six months' treatment with an oral oestrogen-gestogen combination. Comparison with a control group indicated a significant improvement in intestinal absorption after treatment. Though there is no evidence that oestrogens have an anabolic effect on human bone, these results indicate that they affect the intestinal absorption of calcium directly.


"Whistling face" deformity in compound cranio-facio-corporal syndrome.


Associated autonomic dysfunction and carcinoma of the pancreas.


Case of disseminated histoplasmosis.

Case of disseminated histoplasmosis.


Inquiry into administrative activities in general practice.


Design of surgery premises and employment of nurses. The surgery premises of many general practitioners have no accommodation for a nurse. Some have only a nurse/treatment room away from the consulting and examination rooms. Modern designs are no better, and are inadequate in view of the present trend to employ more nurses in group practices. Much of the value of a nurse is lost if she cannot help patient and doctor at the time of examination. The premises described here were designed to enable her to do so by combining the treatment room with a clinical room and a set of examination rooms.


The middle care round.

The middle care round. As an experiment in postgraduate education a 25-week course in weekly ward rounds for general practitioners and local authority nurses was established at a district general hospital of 340 beds. A total of 73 rounds were held, divided into 12-, 4-, and 9-week courses, from January to December 1969. Ninety-nine general practitioners and district nurses (including health visitors) attended one or more of these rounds. Seventeen consultants participated and there were 273 doctor attendances and 190 nurse attendances. The average attendance per round was four doctors and two nurses. The number of rounds conducted by each of the consultants throughout the course varied from two to six. This paper presents an evaluation of the course.


Athletes' deaths.

Athletes' deaths.


Muscular dystrophy in young girls.

Muscular dystrophy in young girls.


Trimethoprim-sulphamethoxazole in typhoid.


Respiratory effects of biological detergents.


Diet and athletics.

Diet and athletics.


Potassium and chronic renal failure.

Potassium and chronic renal failure.


Living it up with Concorde.

Living it up with Concorde.


Recovery from overdose with glibenclamide.


Myocardial infarction and the G.P.

Myocardial infarction and the G.P.


Low-oestrogen oral contraceptives.

Low-oestrogen oral contraceptives.


Reaction to iron sorbitol injection.

Reaction to iron sorbitol injection.


Malignancy and dermatitis.

Malignancy and dermatitis.


Induction of the labour with synthetic oxytocin.


Postoperative leg vein thrombosis.

Postoperative leg vein thrombosis.


Antibiotic therapy and gut flora.

Antibiotic therapy and gut flora.


Pulmonary failure after peripheral injury.


The name of the game.

The name of the game.


The association of phospholipids with anorganic bone.


An electron microscope study of the formation and structure of the periostracum of a gastropod, Littorina littorea.


Effect of starvation and prednisolone administration on collagen and calcium metabolism in mature rats.


The phospholipids of mineralized tissues. I. Mammalian compact bone.


Parathyroid hormone as a stimulus to mast cell accumulation in bone.


Transition of amorphous magnesium ammonium phosphate to a crystalline state in rat urinary calculi induced by L-forms of Proteus mirabilis.


The effect of heat treatment on the structure of kaolin and its in vitro hemolytic activity.


Pathogenesis of pulmonary silicosis in rats fed stock and multideficient diet since weaning.


Measurement of air pollution dosage to human receptors in the community.


Relation of duration of employment and prior respiratory illness to respiratory cancer among beryllium workers.


Effect of experimental hypertriglyceridaemia on tissue and serum lipoprotein lipase activity.


Contribution to the pathogenesis of tumour hypoglycaemia.


Precipitation by neomycin compounds of fatty acid and cholesterol from mixed micellar solutions.


Nonsuppressible insulin-like activity (NSILA) of human serum. V. Hypoglycaemia and preferential metabolic stimulation of muscle by NSILA-S.


Studies on the haemodilution anaemia of splenomegaly.


Comparative effects of exercise and isocapnic voluntary hyperventilation on pulmonary haemodynamics in chronic bronchitis and emphysema.


The effects of X rays on the bronze and shrunken loci in maize.


Dominance in threshold characters. A comparison of two tabby alleles in the mouse.


Comparative studies on X-autosome translocations in the mouse. II. Inactivation of autosomal loci, segregation, and mapping of autosomal breakpoints in five T (X;1) S.


Sperm competition and sperm loss in Drosophila melanogaster females fertilized by YXY-O males.


Dynamics of chromosomal polymorphism and genetic load: an application of the two-locus multiplicative model with heterosis.


The time of initiation of segregational pairing between nonhomologues in Drosophila melanogaster: a reexamination of wm4.


Licensure of nursing home administrators--opportunity and challenge.


Effect of environment on morale.

Effect of environment on morale.


The design of supportive environments for the life-span.


Social planning in Britain.

Social planning in Britain.


Research and public policy: relevance for decision making.


Continuing postgraduate medical education in geriatrics.


Psychiatric consultation: a strategic service to nursing home staffs.


Toward person-environment transactional research in aging.


Cohort analysis with national survey data.


Low-frequency auditory characteristics: Species dependence.


Effect of noise bandwidth on the loudness of a 1000-Hz tone.


Study of single units of the cochlear nucleus of the chinchilla.


Audibility curve of the chinchilla.

Audibility curve of the chinchilla.


Pure-tone auditory behavioral thresholds in three species of lemurs.


Pitch of tone bursts of changing frequency.


Critical-band theory and the auditory-evoked slow-wave V potential.


Temporary threshold shift and damage-risk criteria for intermittent noise exposures.


Hemispheric specialization for speech perception.


Effect of ambient-noise level on threshold-shift measures of ear-protector attenuation.


A simple method for demonstrating an enzymatic reaction.


Iron metabolism in the rat. An experiment in biochemistry.


Isoelectric pH of hemoglobin and cytochrome C by electrofocusing.


Further studies on the reversibility of serum sickness cholesterol-induced atherosclerosis. Rabbits were induced to form atheromatous cardiovascular lesions by subjecting them to treatments of a single BSA injection plus a 2-wk period of cholesterol diet, or to the diet alone. Microscopic examination of the hearts at the end of the 2-wk induction period, or after having been returned to regular diet for 5 or 8 wk, showed that lesion incidence in the cholesterol-only animall decreased markedly during the 8-wk rest period, while little change in incidence occurred in animals with lesions from the combined treatment. This finding was taken to mean that the latter type of lesion was less reversible, and therefore perhaps more pathologically significant, than the former type. It was felt that lipid deposition was not solely responsible for this prolongation, since it was present in diet-only lesions which disappeared with time, and also seemed to be disappearing from the prolonged lesions in all treatment groups. On the other hand, elastic tissue was demonstrated only in lesions arising from the combined treatment, and it is hypothesized that this feature is implicated in the prolongation of these lesions.


Lysis of erythrocytes by complement in the absence of antibody. A new pathway of complement-mediated hemolysis has been described. It is independent of antibody and does not require binding of the first four complement components to the target-cell surface. The actual attack of the target cell begins with the attachment of C5, C6, and C7. The binding reaction is catalyzed by C4, 2, 3, an enzyme which may be formed in cell-free solution. C4, 2, 3 may effect binding of C5, 6, 7 by acting from the fluid phase or from the surface of another cell to which it is specifically bound (EAC 4, 2, 3). In either case, the resulting product is EC5, 6, 7 which is susceptible to lysis by C8 and C9. Erythrocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) were particularly susceptible to lysis by the above described mechanism. PNH cells, but not normal human erythrocytes, could also be lysed through activation of complement by cobra factor. These observations allow the operational distinction of an activation and an attack mechanism of complement.


Complement and complement-like activity in lower vertebrates and invertebrates. A purified cobra venom factor with C-inhibiting activity also promotes lysis of erythrocytes in fresh mammalian serum. Lysis-inducing activity of purified cobra venom factor was found in sera of lower vertebrates including the cyclostome hagfish and in invertebrates. Lysis-inducing activity was most effective with frog serum. Frog serum was found to be more hemolytic for E(s) in the presence of CVF than when cells were sensitized with hemolysin. The hemolysis induced by CVF with frog serum, as in the higher vertebrates, was inhibited when sera were pretreated with known C inhibitors including heat, chelators, endotoxin, immune complexes, and CVF itself. Complexes formed with CVF and either frog serum or invertebrate hemolymph promoted lysis of indicator cells in the presence of frog serum in EDTA. This lysis was most marked when the starfish-CVF complex was used and was C-dependent. Conversely, complex formed with frog serum and CVF promoted lysis of E in the presence of invertebrate hemolymph (Limulus) in EDTA. Hence, serum components were to some degree at least interchangeable between vertebrate sera and invertebrate hemolymph. Lysis-inducing activity of purified CVF occurs in a wide range of species, has revealed activities resembling those of terminal C-components in lower vertebrates and invertebrates, and provides one means for study of C and C-like activities in primitive species.


The effect of heterologous anti-lymphocyte serum on lymphocytes of thymus and marrow origin. When CY-treated mice were given sheep red blood cells the serum hemagglutinin titers produced were significantly lower than those found when mice received SRBC but not CY. Titers could be raised to the levels found in the latter group if, in addition to SRBC, the CY-treated mice received 2 x 10(7) normal syngeneic spleen cells or a mixture containing 1.2 x 10(8) normal thymus and 1.2 x 10(8) normal marrow cells. Inocula which contained fewer cells produced correspondingly smaller amounts of antibody. A synergistic interaction between normal thymus and marrow cells was always demonstrable in these experiments. Hemagglutinin titers produced by CY-treated mice given SRBC and 2 x 10(7) normal syngeneic spleen cells were always much higher than those found when the spleen cells were obtained from animals previously given ALS. Titers could be raised to normal levels if the animals in this latter group received additional injections containing mixtures of normal syngeneic thymus and marrow cells. Marrow cells alone were completely ineffective, while inocula which only contained thymus cells were much less effective than mixtures of thymus and marrow cells. These results suggest that immunosuppression by ALS is associated with the inactivation of both thymus and marrow-derived lymphocytes. In other experiments CY-treated mice received SRBC and mixtures of thymus and marrow cells from both untreated and ALS-treated donors. No decrease in the immunological competence of cells located within the thymus of ALS-treated donors was demonstrable in these experiments. Marrow cells were slightly affected but to a markedly lesser degree than were spleen cells of ALS-treated animals. In a final experiment, it was possible to show that the thymus and marrow cells of ALS-treated animals could repair the immunological defects which were present in their own spleen cell populations.


Electrical correlates of neural superposition in the eye of the fly Sarcophaga bullata.


Effects of chronic excess salt ingestion. Inheritance of hypertension in the rat. TWO STRAINS OF RAT HAVE BEEN DEVELOPED BY SELECTIVE BREEDING: one strain (R rats) is resistant to salt hypertension, the other strain (S rats) is highly susceptible. The inheritance of these traits has been explored in the first (F(1)) and second (F(2)) generation of crossbred rats and in backcrosses between parent and first filial (F(1) x R, F(1) x S) generations. Male F(1) rats had an average blood pressure close to the mid-parental (R and S) values, and the average of F(2) males was equivalent to that of F(1). Male offspring of F(1) with R, or F(1) with S also showed averages close to the respective mid-parental values. Female offspring showed deviations from this linear relationship, indicating a significant dominance in the female for the genes of normal blood pressure. A model of two autosomal, nonlinked diallelic loci, with a dominance deviation at one locus in the female, gave predictions with a reasonable agreement to the observed values. The same model also appeared compatible with human data if we assume a gene frequency of 0.13 for the hypertensinogenic allele on both loci. Random fluctuations in blood pressure, and incomplete homogeneity of parental strains permit several alternative models. The major conclusions are: that more than one locus is needed to explain the findings though as few as two loci may possibly suffice; the allelic effect seems additive in males, but there is a sex-determined influence on the expression in females; there is no consistent evidence for sex-linked inheritance. Furthermore, this model developed from the study of rats may provide a framework for analysis of human data.


Compatibility in insect tissue transplantations. I. Ovarian transplantations and hybrid formation between Drosophila species endemic to Hawaii.


Cell lineage in the dorsal mesothoracic disc of Drosophila.


Biologic activities of peromyscus 7S-gamma-1 and 7S-gamma-2 globulins.


Antigenicity of polypeptides (poly alpha-amino acids): immunogenicity of a homopolymer derivative.


Enhancement by reducing agents of the transformation of human and rabbit peripheral lymphocytes.


A method for typing rabbit sera for the A14 and A15 allotypes with cross-linked antisera.


A pre-albumin activator of prekallikrein.


Experience with a mixed lymphocyte-tumor reaction as a method of detecting antigenic differences between normal and neoplastic cells.


An immunologic marker technique for the Cendehill vaccine strain of rubella virus.


Biologic properties of a mouse IgG2a myeloma protein with anti-dinitrophenyl activity.


Studies on the immune capabilities of chiroptera. I. Quantitative and qualitative nature of the immune responses in bats to bacteriophage phi-X174.


Natural and antibody-induced adherence of guinea pig phagocytic cells to autologous and heterologous thymocytes.


Cellular and antibody reactions to streptococcal M protein types 1, 3, 6 and 12.


Immunologic responses of Pacific hagfish. 3. Serum antibodies to cellular antigens.


Interval flights and glycogen utilization by the mosquito, Culex tarsalis.


Cytological and cytochemical studies on the ejaculatory duct and accessory secretion in Musca domestica.


Salivary secretion of the male tick during copulation.


Use of the faecal uric acid method in measuring the utilization of food by Tribolium confusum.


The pleural reaction to injury: a histological and electron-optical study with special reference to elastic-tissue formation.


The migration of cells through chronically inflamed tissues.


Permeability of pancreatic endothelium to horseradish peroxidase.


Aortitis in early life in India and its association with tuberculosis.


Modification of radiosensitivity of Ehrlich ascites carcinoma cells in vivo. 1. Some basic experiments on the role of lethally irradiated tumor cells.


Measurement of absorbed dose rate from terrestrial background radiation in Hong Kong.


Comparative protective effect of AET against fast neutron and x-ray irradiation on mortality, intestinal disorders and hematopoietic injuries in mice.


Effects of x-irradiation on 14C-pyruvate metabolism in rat thymocytes.


Effects of cobalt-60 gamma rays on lysozyme in aqueous solution.


The determination of plutonium in soil samples.


The genus Syringospora Quinquad emend.

The genus Syringospora Quinquad emend.


The occurrence of fungi in activated sludge.


Electronmicroscopy of self-parasitism by Histoplasma capsulatum and Blastomyces dermatitidis.


Metabolic rate of fungi as a function of temperature and oxidation-reduction potential (EH).


Absence of interaction between photoreactivation and temperature-dependent dark recovery of ultraviolet irradiated yeasts.


Use of paraffin bait technique in the isolation of Nocardia asteroides from sputum.


First mention of Nannizzia persicolor (Trichophyton or Microsporon?) Stockdale, 1967 in Romania.


A clinical study on serial retrograde venography of the lower extremity with varicose veins.


A possible role of pyridoxine in lipid metabolism.


Long lasting extracorporeal circulation with membrane oxygenator during normothermia and profound hypothermia.


Evoked potentials elicited by stimulation of the caudate nucleus and internal capsule with multilead electrode.


An automatic alarm system: for use in the management of respiratory ventilation.


Mental illness and the district nurse. 1. Organic and neurotic reactions.


Cardiac catheterization in Scandinavia.

Cardiac catheterization in Scandinavia.


The clinical use of ketamine hydrochloride.


The packaging and presentation of sterile packs.


Nursing and the universities. A student's view.


Sixth-formers and psychiatric hospitals.


Men who come into nursing. 1.

Men who come into nursing. 1.


"Require no visiting".

"Require no visiting".


Artificial ventilation. 3. Nursing care.


Working on the roof of the world. The Britain-Nepal Medical Trust.


How to upgrade a Victorian workhouse. The changing scene: Bridgewater Hospital, Patricroft.


Mental illness and the district nurse. 2. Depression, psychosis and mental deficiency.


Men who come into nursing. 2.

Men who come into nursing. 2.


The differential diagnosis of normal and neurotic grief following bereavement.


Frigidity: a factor analytic study of a psychosomatic theory.


Nonverbal behavior in a selected group of Negro and white males.


Can psychopharmacology advance?

Can psychopharmacology advance?


Psychiatric aspects of patients with compensation problems.


Quantitative assay of bufotenine in psychiatric outpatients.


Psychosomatic skin disorders in survivors of Nazi concentration camps.


Anxiety and depression in medical practice.


The impact of psychopharmacology on medicine and psychiatry.


The pill head menace. Barbiturates and tranquilizers non-hard core addicting drugs.


Hypochondriasis: symptom or entity.

Hypochondriasis: symptom or entity.


The VA-NIMH study of lithium in affective disorders.


Clinical and biochemical aspects of depression.


The recognition and management of depression.


Comparative efficacy of thiothixene capsules and concentrate in acutely schizophrenic patients.


Reactive depression as a model psychosomatic disease.


Depressive reactions of childhood and adolescence.


Television tape for evaluation of treatment response.


Use of a thyroid hormone to accelerate the action of imipramine.


Psychosomatic allergy.

Psychosomatic allergy.


Lithium, creativity, and manic-depressive illness: review and prospectus.


Organic Integrity Test (OIT) in monitoring drug effects.


Recognition and treatment of youthful depression in a rural area.


The use of high doses of fluphenazine in the treatment of psychotic patients.


Fluid and electrolyte abnormalities in alcoholism.


The variables of silent myocardial infarction in a psychotic population.


A survey of anti-anxiety agents used over the past 30 years.


Biogenic amines and schizophrenia.

Biogenic amines and schizophrenia.


Tofranil in the treatment of post alcoholic depressions.


Medical management of the alcohol withdrawal syndrome.


Orthomolecular psychiatry: niacin and megavitamin therapy.


Spasmophilia caused by magnesium deficit.


Dysautonomia in schizophrenic remission.


Problems regarding the introduction of a psychopharmaceutical agent in international markets.


Psychopharmacology and general adaptation syndrome.


Effect of a stable free-radical on the survival of X-irradiated mice.


Pellagra and schizophrenia.

Pellagra and schizophrenia.


Evidence for the production of Foà-Kurloff cells by the spleen of guinea-pigs.


A note on the gram negative bacilli of human skin.


Mycetoma caused by Streptomyces somaliensis in North India.


Contribution to the study of the solubilization and purification of H-2 antigens obtained from BP-8 murine cell membranes.


The plasma clearance of synthetic emulsions of triglycerides containing long chain fatty acids and medium chain fatty acids.


Electron microscopy of aspergillosis in fowl chicks.


A reappraisal of the microscopical appearance of the mycelial phase of Paracoccidioides brasiliensis.


Peyronellaea glomerata infection of the ear pinna in goats.


"In vitro" immunisation by antilymphocyte serum. II.


Psychiatric disorders accompanying epilepsy in children.


Ecology and transmission of Microsporum gypseum from soil to man.


Electron microscopy of conidiospore formation in Aspergillus niger.


The psychiatric-psychological results of operation on the temporal lobe in epileptic children.


Psychiatric disorder in children with neuro-epileptic handicaps.


Recalcitrant honey bees.

Recalcitrant honey bees.


Phialophora dermatitidis; its morphology and biology.


Yogurt fit for an Armenian.

Yogurt fit for an Armenian.


Vietnamese pacification program.

Vietnamese pacification program.


Nerve gas: judging the risks.

Nerve gas: judging the risks.


Coitus-induced ovulation.

Coitus-induced ovulation.


The analysis of pesticide residues: new problems and methods.


Human injury inflicted by grizzly bears. Grizzly bear (Ursus arctos horribilis) attacks resulting in human injury and known to have occurred in the national parks of North America were examined. Fifty-seven attacks in which 61 persons were injured took place in three national parks in the United States and accounted for 79 percent of the known injuries. The remaining 16 injuries occurred in four Canadian national parks. The 77 injured persons gives an injury rate of 1 person per 2 million visitors.


Science funds: NSF survey probes effects of shifts in Federal aid.


Science policy: Daddario panel urges new study, changes in OST.


Soluble HL-A7 antigen: localization in the beta-lipoprotein fraction of human serum. The HL-A7 antigen of human leukocytes occurs as a soluble, low-density lipoprotein in the serum of HL-A7-positive individuals. Its presence in high concentration may inhibit direct leukocyte grouping, leading to erroneous results. This finding affords an easy method for the preparation of monospecific cytotoxic antiserums by absorption with serum fractions rather than leukocytes.


Localization of 5S RNA genes on Drosophila chromosomes by RNA-DNA hybridization. [(3)H]RNA with a high specific activity was prepared from larvae of Drosophila melanogaster grown 4 days in contact with [(3)H]uridine. Purified tritiated 5S RNA was annealed to the DNA of polytene chromosomes, which had been denatured in formamide. The 5S RNA genes are placed within the region 56E-F of the right arm of chromosome 2. This localization was determined from autoradiographs, where the radioactivity from hybrids of [(3)H]RNA and DNA was confined to the 56E-F segment.


Cochlear summating potentials: composition. The potential difference across the cochlear partition and the overall potential level of a given cochlear cross section were measured as functions of stimulus parameters and spatial location. It was confirmed that the potential difference is negative in the vicinity of greatest excitation, and it was discovered that in the same region the overall potential level is positive.


Intelligence quotient pattern over age: comparisons among siblings and parent-child pairs. Comparisons between sibling and parent-child pairs with unrelated control pairs matched for year of birth and parental education were made to determine the relative heritability of the general level of intelligence quotient as opposed to that of the sequential pattern of IQ change over age (3 to 12 years). There was greater similarity among related siblings relative to matched controls for general level than for pattern of IQ over age. Relationships between the IQ's of children and that of their parents as children were not consistent across age.


Interference of HEPES with the Lowry method.


Brood care in halictid bees.

Brood care in halictid bees.


Urbanization in the arid lands.

Urbanization in the arid lands.


The organisation of a transplant unit.

The organisation of a transplant unit.


Analytical and preparative thin-layer chromatography of porphyrin methyl esters.


Formation of zinc chelates from porphyrin methyl esters for spectrophotometric analysis.


Nicotine and arteriosclerosis. An experimental contribution to the influence of nicotine on fat metabolism.


Thin-layer chromatographic determination of L-ascorbic, L-dehydroascorbic nd 2.3-diketo-L-gulonic acids in animal tissues, blood and urine.


The fasting metabolism of Brahman, Africander and Hereford X Shorthorn cattle.


Effect of riboflavine deficiency on incorporation in vivo of [14C]amino acid into liver proteins of rats.


Urinary creatinine and hydroxyproline in relation to childhood malnutrition.


The effect of phosphate and carbonate-bicarbonate supplements on the rumen buffering systems of sheep.


Influence of starch digestion in the large intestine of sheep on caecal fermentation, caecal microflora and faecal nitrogen excretion.


The effect of folic acid and iron in the prevention of nutritional anaemias in pregnancy in Nigeria.


The effect of diet on the haemoglobin and haematocrit values of some Nigerian village children.


The preparation of nutritious protein from wool.


The uptake of radioactive copper by the brain and other tissues of the developing rat.


Utilization of salts of volatile fatty acids by growing sheep. 5. Effects of type of fermentation of the basal diet on the utilization of salts of acetic acid for body gains.


The effect of dilution of milk proteins with non-essential amino acids (L-alanine and L-glutamic acid) on nitrogen retention and biological value of the proteins in children.


The influence of the amount and nature of dietary fat on milk fat composition in the sow.


The protein quality of cassava leaves.

The protein quality of cassava leaves.


The effects of feeding procedure on closure of the oesophageal groove in young sheep.


Cassava diet and cyanide metabolism in Wistar rats.


Salt intake in Ceylon.

Salt intake in Ceylon.


Ascorbic acid status of Europeans resident in the tropics.


The use of ultrasound in the diagnosis of pelvic masses.


Artificial rearing of pigs. 2. The time course of milk protein digestion and proteolytic enzyme secretion in the 28-day-old pig.


Digestion and nitrogen metabolism in sheep and red deer given large or small amounts of water and protein.


A ruler-protractor for direct measurements of angles and distances on radiographs.


How many rads per Paterson-Parker röntgen?


Computers in radiotherapy.

Computers in radiotherapy.


Improvements in intravenous cholangiography.


Treatment plan optimisation by the use of photographic film densitometry and closed-circuit television.


The 100 mm (4x4 in.) film as a basic unit for x-ray filing.


The use of carbon 11 dioxide for skeletal scintigraphy.


Glucose tolerance sum criteria in patients.


Infusion chemotherapy for metastatic liver cancer.


The role of erythrocytes in blood clotting in the light of own investigations.


Coma in the course of Addison-Biermer's anemia.


An unusual case of Wolff-Parkinson-White syndrome with features of the pre-excitation complex of Oehnell.


Hypoplastic left heart complex.

Hypoplastic left heart complex.


Partial glucose intolerance by various criteria.


Citations in chemistry.

Citations in chemistry.


UKCIS-the United Kingdom chemical information service.


Interconversion of chemical structure systems.


The chiral methyl group--its biochemical significance.


The Medical Research Council.

The Medical Research Council.


Reduction of 4-aza-5-cholesten-3-one to 4-aza-5 alpha-cholestan-3-one under conditions of the Leuckart-Wallach reductive amination.


Eastern equine encephalitis virus infection: electron microscopic studies of mouse central nervous system.


Virus-like particles in developing plasma cell tumors induced in BALB-c mice.


Pulmonary vascular occlusions initiated by endothelial lysis in monocrotaline-intoxicated rats.


The aortic tunica media in aging rats.

The aortic tunica media in aging rats.


The ultrastructure of neointima of canine infrarenal vena caval Teflon prostheses.


Comparison of methyl-labeled tRNA in a neoplastic cell line with a paired non-neoplastic control.


Effects of phenobarbital pretreatment on the hepatotoxicity of carbon tetrachloride.


The amino acid sequence of T4 phage lysozyme. I. Tryptic digestion.


The amino acid sequence of T4 phage lysozyme. II. Chymotryptic digestion.


The amino acid sequence of T4 phage lysozyme. IV. Dilute acid hydrolysis and the order of tryptic peptides.


The complete amino acid sequence of papain. Additions and corrections.


Primary structure of staphylococcal enterotoxin B. I. Isolation, composition, and sequence of tryptic peptides from oxidized enterotoxin B.


The primary structure of staphylococcal enterotoxin B. II. Isolation, composition, and sequence of chymotryptic peptides.


The primary structure of staphylococcal enterotoxin B. 3. The cyanogen bromide peptides of reduced and aminoethylated enterotoxin B, and the complete amino acid sequence.


5-hydroxy-N-methylpyroglutamate synthetase. Purification and mechanism of action.


An assessment of in vivo mitochondrial protein synthesis in Neurospora crassa.


(1-14C)glucosamine incorporation by subcellular fractions of small intestinal mucosa. Identification by precursor labeling of three functionally distinct glycoprotein classes.


Intramitochondrial localization of kynurenine aminotransferase.


The oxygenated form of L-tryptophan 2,3-dioxygenase as reaction intermediate.


Thyroxine degradation during lipoxidase-catalyzed peroxidation of linoleic acid.


The purification and partial characterization of gluconokinase from a pseudomonad.


Isolation and physicochemical characterization of luteinizing hormone from human pituitary glands.


Effects of ring geometry on triplet and singlet energies of the metal mesoporphyrins.


Defective myelopoiesis in congenital neutropenia.


Granulomatous colitis in association with diverticula.


Hyperthyroidism due to thyrotropin-producing pituitary chromophobe adenoma.


Biochemical screening--a critique.

Biochemical screening--a critique.


Multiphasic health testing and medical care as a right.


Anomalous systemic arterial supply to the lung causing pulmonary-artery hypertension.


Complete heart block with thyrotoxic myocarditis. Report of a case.


Patterns and prognosis in hepatitis.

Patterns and prognosis in hepatitis.


Impaired maturation of neutrophils.

Impaired maturation of neutrophils.


Judge Baker guidance center.

Judge Baker guidance center.


Electrocardiographic changes during cardiac pain.


Tinea nigra palmaris resembling malignant melanoma.


Measurement of 2,3-DPG.

Measurement of 2,3-DPG.


Dislocation of the shoulder: x-ray signs.


The silent debits of multiphasic screening.


All work and no play.

All work and no play.


Up-to-date scalp tonic.

Up-to-date scalp tonic.


Conspiracy.

Conspiracy.


Effect of sensitization on gastric secretion and motility.


Glucose-6-phosphatase activity on bivalent metallic ions.


Effects of lysergic acid diethylamide (LSD25) on short-term memory in cat.


Comparative radiology of the proximal gastro-intestinal tract in Jamaica.


Deafness in tropical nutritional ataxic neuropathy.


Cardiovascular disease in Djakarta, Indonesia in private and in municipal outpatient practice.


Conservative medical treatment of uterine rupture.


Mass trivalent oral polio vaccination in primary school age children in Teheran.


Eruption times of permanent teeth and the determination of age in New Guinean children.


Parasites and epilepsy in Nigeria.

Parasites and epilepsy in Nigeria.


Schistosomiasis at Lake Kariba, Zambia. II. Transmission of Schistosoma haematobium and S. mansoni at Siavonga.


The present status of onchocerciasis in Tanzania. A review of the distribution and prevalence of the disease.


Comparative studies of some recently described new leptospiral serotypes.


Comparison of three strains of Toxoplasma gondii by polyacrylamide-gel electrophoresis.


Protein-calorie malnutrition syndrome in adults. Four case reports.


Renal tuberculosis. A case report.

Renal tuberculosis. A case report.


Maternal and child health planning: a framework.


Polarography of some sulphur-containing compounds. XVI. Polarographic and spectral investigation of acid-base equilibria in aqueous solutions of 2-thiobarbituric acids with substituents on sulphur.


Correlations between 31 P n.m.r chemical shifts and structures of some organophosphorus pesticides.


A rapid method for the determination of polonium-210 and lead-210 in sea water.


The coulometric titration of barbiturates.


Enzymatic methods of analysis. Trace analysis of various pesticides with insect cholinesterases.


Pseudopili annulati; an unusual variant of normal hair.


Metabolic alkalinization therapy in porphyria cutanea tarda.


Pemphigus vulagis involving the esophagus.


Connective-tissue nevus. Dermatofibrosis lenticularis disseminata with osteopoikilosis.


Polydysplastic epidermolysis bullosa and deelopment of epidermal neoplasms.


Experimental contact sensitization with benzoyl peroxide.


Aminobenzoic acid and its esters. The quest for more effective sunscreens.


Papular angioplasia. Vascular papules of the face and scalp simulating malignant vascular tumors.


Nevus spilus.

Nevus spilus.


Topical medications on dermabraded tattoos.


Tubular plastic as an occlusive dressing.


Guttate leukoderma in Darier's disease.

Guttate leukoderma in Darier's disease.


Eczema vaccinatum in Darier's disease.

Eczema vaccinatum in Darier's disease.


Kaposi's sarcoma localized to the penis.


Primary localized amyloidosis of glans penis.


Unusual cutaneous lesions in tumoral calcinosis.


Superficial multicentric basal cell epithelioma arising in thermal burn scar.


Malignant acanthosis nigricans.

Malignant acanthosis nigricans.


Radioactive iodine treatment of euthyroid cardiac disease. A seventeen year follow-up.


A vectorcardiographic study of the P loop using high amplification techniques. Analysis of 135 cases.


Heart-reactive antibody, serum enzymes and isoenzymes in the diagnosis of acute rheumatic fever.


Electrical cardiac pacing in patients without heart block.


In-vivo intestinal mucosal uptake of iron, body iron absorption and gastric juice iron-binding in idiopathic haemochromatosis.


Factors influencing the prognosis of the alcoholic patient with cirrhosis.


Effect of vagotomy on serum gastrin in patients with duodenal ulceration.


Leber's optic atrophy: a possible example of vertical transmission of a slow virus in man.


Hyperosmolality in leptospirosis.

Hyperosmolality in leptospirosis.


Periodic diseases.

Periodic diseases.


Time must have a stop.

Time must have a stop.


Peripilar keratin casts.

Peripilar keratin casts.


Familial trichoepithelioma of unusual distribution.


Occurrence of squamous carcinoma in hyperkeratoses and Bowenoid lesions treated with 5-fluorouracil.


Pili annulati.

Pili annulati.


Apocrine cystadenoma.

Apocrine cystadenoma.


Case report: angiokeratosis naeviformis.


Epidermolysis bullosa--illustrating difficulty in classification.


Allergic vasculitis.

Allergic vasculitis.


Ichthyosis--sex-linked recessive type.

Ichthyosis--sex-linked recessive type.


Cholinergic urticaria with systemic presentation.


Cholinergic flushing: cholinergic urticaria: flexural dermatitis.


Cholinergic pruritus.

Cholinergic pruritus.


Multiple cutaneous, osseuous, ocular and neuromuscular defects.


Perimetric study in basilar impression.

Perimetric study in basilar impression.


Flexion contractures in Addison's disease.


Measurement of unit activity in various systems of the brain postoperatively; a preliminary study.


Investigation of gastroesophageal reflux in various positions with a two-lumen pH electrode. Normal people without symptoms of reflux do in fact reflux small quantities of acid into the oesophagus when either standing or sitting, but do not reflux acid when they are sleeping lying flat. This ;physiological' incompetence in the upright position is not of great importance in that the oesophagus is able to, and consistently does, deal with small concentrations of refluxed acid material. The oesophageal measurements of pH have a limited use as a diagnostic measure and may indicate acid reflux in the relaxed person not demonstrated by radiology.


Sex hormones, and acid gastric secretion induced with carbachol, histamine, and gastrin. This study confirms previous reports that satisfactory gastric acid secretory responses to intravenous administration of histamine, carbachol, and gastrin can be obtained. Bilateral castration of the male rats significantly reduced acid gastric secretory responses to carbachol but not to histamine. Overiectomized rats treated with 17B-oestradiol (short-term treatment) showed a statistically significant reduction in gastric acid secretion induced with all the secretagogues, but the results when rats were treated with testosterone were inconsistent. In animals given gastrin or histamine gastric acid secretion was reduced and was of statistical significance with gastrin (0.02 < p < 0.05) but not with histamine (0.05 < p > 0.1). It is concluded that a high oestrogen blood level is capable of inhibiting effectively acid gastric secretion in both sexes except that a higher level of blood oestrogen is required in the male. The results showed further that of all the sex hormones used, only oestrogen had a significant effect on gastric acid secretion.


The transport of colonic contents in the irritable colon syndrome. The mean distance of travel and hourly incidence of propulsive and retropulsive movements of colonic contents have been assessed by means of time-lapse cinefluorography and compared in 98 patients with the irritable colon syndrome and in 90 control subjects.Net propulsion in patients with the irritable colon syndrome was less than in the controls at rest, similar to the controls after feeding, and greater than in the controls after an injection of carbachol. In both clinical groups, food and carbachol increased the incidence of propulsive and retropulsive movements but did not alter the average distance over which they travelled.The figures suggest that at least two-thirds of all net propulsion of colonic contents in the irritable colon syndrome takes place under circumstances not reproduced in the present study.


The association between aneurysm of the abdominal aorta and peptic ulceration. In a survey of 7,044 necropsies there were 99 cases of aneurysm of the abdominal aorta and 523 cases of peptic ulceration. The incidence of peptic ulceration in the general necropsy population was 7.2% whilst in cases with aneurysm it was 22.6%. There was a significant increase in duodenal ulceration in males with abdominal aortic aneurysms. The possible causes for this increased incidence are discussed.


Recurrent perforation of the ileum.

Recurrent perforation of the ileum. Ulceration of the small intestine is rare, perforation of such ulcers is also rare, and repeated perforation is still rarer. A case with this history is presented, and the aetiology of such cases briefly discussed, as the current literature gives a varied emphasis regarding the important causes of ulceration of the small intestine.


Faecal stasis and diverticular disease in ulcerative colitis. The incidence of faecal stasis and of diverticular disease has been studied in a group of 399 patients with ulcerative colitis. Sixty-one patients had faecal stasis and 23 patients had diverticular disease. Pathological studies demonstrated an increase in the thickness of the inner spiral muscle in colitis patients with faecal stasis. The thickening was not as great as that seen in diverticular disease. Preliminary studies on the motility patterns in patients with faecal stasis show a higher mean activity in the pelvic colon than in normals but not as great as that seen in diverticular disease. Pressure studies in patients with faecal stasis have shown hypotonia in the proximal colon associated with dilatation.The possible significance of these results is discussed. It is suggested that ulcerative colitis may initiate a motility disturbance which leads to muscle thickening similar to that in diverticular disease. Diverticula associated with ulcerative colitis are usually not involved in the mucosal inflammatory process.


The relationship between flow and electrolyte secretion in the canine pancreas. The response of the pancreatic bicarbonate secretory mechanism to secretin and the relationship between bicarbonate concentration and flow rate in pancreatic juice have been re-examined following reports describing decreasing levels of bicarbonate concentration at high flow rates. Both anaesthetized and chronic fistula dogs were used. The results show that when high doses of secretin elicit high rates of flow of pancreatic juice the bicarbonate concentration rises to a peak which is constant over a wide range of stimulation and flow rates.


Lipid composition of heteroploid cells in culture: effects of prednisolone.


Hemopoietic stem cell distribution in tissues of fetal and newborn mice.


Growth kinetics of hemopoietic fetal stem cells.


Variation in the latency of acid phosphatase and ribonuclease throughout the growth cycle of Tetrahymena pyriformis.


Human bone marrow colony growth in agar-gel.


Histidase function in human epidermal cells.


A new method of cloning mammalian tissue culture cells in suspension.


Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor.


Effects of nitrogen fertilization on the thyroid function of rats fed 40 percent orchard grass diets.


The site of calcium absorption in the horse.


Inhibition of cholesterol deposition in livers of mice fed phytosterols in short-term experiments.


Influence of acute nutritional stress on polyribosomes and protein synthesis in brain and liver of young rats.


Effect of maternal diet in rats on feed consumption of the offspring.


Effect of diets of different protein values on the development of osteolathyrism in rats given beta-aminopropionitrile.


Efficiency of protein utilization in young rats at various levels of intake.


Intestinal absorption of sodium and potassium in the laying fowl.


Zinc deficiency and urinary excretion of taurine-35S and inorganic sulfate-35S following cystine-35S injecion in rats.


Skeletal and plasma calcium changes in chicks during recovery from vitamin D deficiency with normal and low calcium intakes.


Effect of glycine and serine on methionine metabolism in rats fed diets high in methionine.


Recovery of radioactive chromic oxide from the bovine gastrointestinal tract.


Fees for medical attendances after hours.


Research coordination in the Territory of Papua and New Guinea.


An address.

An address.


Occult rupture of the spleen.

Occult rupture of the spleen.


Tuberculin testing with disposable plastic syringes.


Disseminated aspergillosis as a complication of multiple myelomatosis.


An assessment of "Fiorinal" and FIPA in painful conditions of the hands.


The epidemiology of drug overdosage.

The epidemiology of drug overdosage.


Propanidid in anaesthesia.

Propanidid in anaesthesia.


The common cold.

The common cold.


The report of the director-general of health.


The value of physiotherapy in obstetrics.


Bilingual prescribing and dispensing.

Bilingual prescribing and dispensing.


Neurological complications of glandular fever.


Irradiation gastritis simulating carcinoma.


The silicone foam enema as a source of cytological specimens from the left colon.


Search for trichinella infection in Western Samoa and Fiji.


Splenomegaly in analgesic takers.

Splenomegaly in analgesic takers.


Training for careers in the Australian health services.


The management of advanced breast cancer.


Speech changes after pharyngeal flap surgery.


Subjective evaluation of the face-lift and eyelid operations. A preliminary report.


Growth and development in replanted forelimbs.


The island flap in secondary cleft palate surgery.


The upright position for hair transplantation.


Abnormal anatomy of the muscles of palatopharyngeal closure in cleft palates: anatomical and surgical considerations based on the autopsies of 18 unoperated cleft palates.


A thermoplastic splint for the nose.

A thermoplastic splint for the nose.


The difference between mutagenesis and teratogenesis, or how to tell the players from the spectacles.


Teratology in 1970: the national scene. President's Report to the Teratology Society.


Effects of transitory maternal pteroylglutamic acid (PGA) deficiency on levels of adenosine phosphates in developing rat embryos.


Kidney malformations in fetuses of A x C line 9935 rats.


The relation of the uterine vasculature to fetal growth and the intrauterine position effect in rats.


Teratogenic effects of direct injection of aqueous and protein-bound trypan blue into the bloodstream of 3-day chick embryos.


Attempts to isolate H-1 virus from spontaneous human abortions: a negative report.


Ultrastructural changes in nurse and follicle cells during late stages of oogenesis in Drosophila melanogaster.


Electron microscopic observations on synapse-like contacts between pituicytes and different types of nerve fibers in the anuran pars nervosa.


Nucleosphaeridies in early pig embryos.

Nucleosphaeridies in early pig embryos.


Fine structure of the corpus allatum of the female blow-fly Calliphora erythrocephala.


The nucleus lateralis tuberis system of the gobiid fish Gillichthys mirabilis. I. Ultrastructural and histochemical characterization of the nucleus.


The reliability of electrocardiographic criteria of chronic obstructive lung disease.


The effect of oral quinidine on intraventricular conduction in man: correlation of plasma quinidine with changes in QRS duration.


Autonomic blockade and the resting heart rate in man.


Serum lactic dehydrogenase activity in patients with prosthetic heart valves: a parameter of intravascular hemolysis.


The use of propranolol in arrhythmias complicating acute myocardial infarction.


The genesis of the cervical venous hum.

The genesis of the cervical venous hum.


Right atrial-left ventricular relationships in tricuspid atresia: position of the presumed site of the atretic valve as determined by transillumination.


The direct diagnosis of human myocardial ischemia using 131I-MAA via the selective coronary catheter. Preliminary report.


Left ventricular transverse internal diameter: value in studying left ventricular function.


Effects of the Valsalva maneuver on the cardiac systolic intervals: beat-to-beat versus timed analysis.


Experimental cobalt cardiomyopathy.

Experimental cobalt cardiomyopathy.


Peripheral venospasm associated with signs of transient myocardial ischemia.


Opening snap of the tricuspid valve in atrial septal defect. A phonocardiographic and reflected ultrasound study of sounds in relationship to movements of the tricuspid valve.


Pathogenesis of "rheumatic" heart disease:critique and theory.


Clinical pathologic conference.

Clinical pathologic conference.


Chlorpromazine in the treatment of cardiogenic shock.


Intracranial lesions and the heart.

Intracranial lesions and the heart.


Nomograms for determination of mixed venous oxygen content and oxygen step-up in atrial septal defect.


Myocardial infarction complicating surgical operations.


Pacemaker rhythms.

Pacemaker rhythms.


Evaluation of a direct reading spectrophotometer for neonatal bilirubinometry.


Evaluation of methods for calibration of O2 and CO2 electrodes.


Serum copper and zinc levels in various pathologic conditions.


Identification of mycobacterial pathogens utilizing colony characteristics.


Identification of enteric bacilli directly from primary isolation media using reagent-impregnated paper strips.


Pseudomonas pseudomallei in a case of chronic melioidosis.


Fatal infection due to Chromobacterium violaceum in Vietnam.


Detection of coproantibodies in amebiasis of the colon: a preliminary report.


The anorectal myenteric plexus: its relation to hypoganglionosis of the colon.


Ultrastructure of a cardiac myxoma.

Ultrastructure of a cardiac myxoma.


Enteritis cystica polyposa.

Enteritis cystica polyposa.


Prothrombin time standardization.

Prothrombin time standardization.


Suppurative pelvic thrombophlebitis. A study of 202 cases in which the disease was treated by ligation of the vena cava and ovarian vein.


Renal hemodynamic effects of oxytocin in antepartal and postpartal women.


Ultrasonic studies on the volumetric growth of the human placenta.


Control of pulmonary and systemic vasomotor tone in the fetus and neonate.


Sexual maturation in contemporary American girls.


The right and the responsibility.

The right and the responsibility.


Regulation of glycogen metabolism in the adrenal gland. I. Kinetic and regulatory properties of glycogen synthetase.


The effect of chloramphenicol and cycloheximide on lipid synthesis during chloroplast development in Euglena gracilis.


The 520-nm absorption change in barley and a chlorophyll b-deficient mutant.


Formation constants of weak complexes. Determination for HgClBr by countercurrent distribution.


Distribution of radioactive hemoprotein and CO-binding pigment in rough and smooth endoplasmic reticulum of rat liver.


Early reactions in photosynthetic energy conservation: the photooxidation at liquid nitrogen temperatures of two cytochromes in chromatophores of Rhodopseudomonas gelatinosa.


Mechanistic studies of beef liver mitochondrial amine oxidase. 18. Amine oxidase.


Properties of liver glycogen isolated in density gradients of sodium iothalamate.


Quinone restoration of coupled phosphorylation in Mycobacterium phlei.


Water and solute binding by proteins. II. Denaturants.


Scientific thought: a force in human life.


Purification and properties of an acid phosphatase from bovine brain.


Stereopsis, visual latency, and three-dimensional moving pictures.


The transfer of immunological competence to rats tolerant of sheep erythrocytes with lymphocytes from normal rats.


The influence of synthetic oestrogen and progestogen on the rat myocardium.


The role of the kidney in albumin, transferrin and IgG catabolism in the rat.


Increased uptake and efflux of calcium with acetylcholine stimulation in smooth muscle of toad stomach.


The absorption of iodovancomycin by micrococcus lysodeikticus cells.


The effect of fasciolosis on the wool production of merino sheep.


Hydatidosis and cysticercosis. 3. Induced resistance to the larval phase.


Transmission of Fusiformis nodosus infection from cattle to sheep.


Mycoplasmas isolated from cattle in Australia.


The action of phenanthroline metal chelates and related substances on Erysipelothrix rhusiopathiae and Fusiformis nodosus.


The medical role of the veterinarian in nuclear disaster in Australia.


Structure and function of the Technical Committee on Veterinary Drugs.


Tocopherol concentrations in the serum and liver of lambs with white muscle disease.


Thrombolytic therapy in arterial and venous thrombosis.


Treatment of acute and chronic arterial occlusions with streptokinase.


The use of thrombolytic therapy in obstetrics and gynaecology.


Streptokinase in the treatment of major pulmonary embolism--experience with twenty-five patients.


Incidence of thrombosis in myocardial infarction.


Thrombolytic therapy in acute myocardial infarction.


Experimental thrombosis and prevention by drugs that interfere with platelet aggregation.


Low-temperature extraction of alpha-actinin-like protein from the I-Z-I brush of striated muscle.


Exhaustive extraction of the troponin-tropomyosin factor from the I-Z-I brush of striated muscle.


Reaction of myosin with salicylaldehyde. I. The effect of salicylaldehyde on the physicochemical properties of myosin.


Fluorescence characteristics of lyophilized maize chloroplasts suspended in buffer.


Fluorescence spectra of Chlorella in the 295-77 degree K range.


Control of excitation transfer in photosynthesis. IV. Kinetics of chlorophyll a fluorescence in Porphyra yezoensis.


A study of chlorophyll b in vivo.

A study of chlorophyll b in vivo.


Regulatory effects of ammonia on carbon metabolism in photosynthesizing Chlorella pyrenoidosa.


Particulate formate oxidase from Nitrobacter agilis.


Studies in bioluminescence. 3. The Pholas dactylus system.


Na+ and K+ in outer segments of retinal rods.


Effect of valinomycin on mitochondrial ultrastructure and function of intact Ehrlich ascites tumor cells.


Organization and regulation of fatty acid oxidation in mitochondria of brown adipose tissue.


Oxidative phosphorylation in yeast. VII. Inhibition of oxidative phosphorylation and of respiratory enzyme synthesis by oligomycin in intact cells.


Circadian variation in ATP content in the chloroplasts of Acetabularia mediterranea.


Effect of insulin on metabolism of adipose tissue in goats during ontogeny.


Catheterization of the urinary bladder in young female animals.


Changing the rules.

Changing the rules.


Patient monitoring in a neurosurgical environment.


Fault-finding and care of laboratory equipment.


Standardisation of microphones for phonocardiography.


Tests of pancreatic function.

Tests of pancreatic function.


Subcutaneous surgical emphysema and abscess in colonic carcinoma.


Anaplastic carcinoma of the lung and sarcoidosis.


Illness in publicans-hazards of misdiagnosis.


Two hernias, irreducible but innocent.

Two hernias, irreducible but innocent.


Unusual oesophageal hiatus hernia.

Unusual oesophageal hiatus hernia.


A bloodless operation for spermatocoele or cyst of the epididymis.


Peritoneal mesothelioma. A report of 4 cases.


Starch granuloma (pseudo-malignant seedlings).


Eosinophilic gastro-enteritis.

Eosinophilic gastro-enteritis.


Medullary carcinoma of the thyroid with hypocalcaemia. Clinical and ultrastructural observations.


The treatment of anterior chest wall injuries.


The management of gangrenous sigmoid volvulus.


Emergency by-pass of the thoracic aorta. Experimental evaluation of a simple method.


Tuberculous osteitis of the skull.

Tuberculous osteitis of the skull.


Intussusception in infancy and childhood.


Intracardiac foreign bodies.

Intracardiac foreign bodies.


The clinical and operative diagnosis of Maydl's hernia. A report of 5 cases.


Clinical aspects of cholecystoduodenocolic bands.


Traumatic perforation in carcinoma of the oesophagus.


Haemorrhage-induced breast gangrene.

Haemorrhage-induced breast gangrene.


Eosinophilic granuloma of the gastro-intestinal tract. Case report and suggested classification.


Cystic adventitial disease of the popliteal artery.


Primary fibrosarcoma of lung and diabetes mellitus.


Blindness following relief of increased intracranial pressure. A sequel to severe papilledema.


Electromyographic abnormalities in a case of botulism.


Cellulolytic activity in municipal solid waste composting.


Effects of some phenylamide herbicides and their degradation products on soil nitrification.


Factors affecting the production of m-cresol by Valsa friesii.


Control of Fusarium wilt of muskmelon and other effects of benomyl soil drenches.


Low temperature vacuum drying of sterile parenterals from ethanol.