Effect of hypophysectomy ans substitution therapy with STH upon experimental bone lathyrism.


The stability of packaged pharmaceuticals as related to glass chemical durability.


Studies on the nephrotoxicity of 5-hydroxytryptamine (enteramine) in the rat.


Testing for sterility of corn oil. I. Dispersion of spores in corn oil and in saline.


Streptococcal cardiac lesions in rabbits.


The changing cellular distribution in bone marrow of the normal albino rat between one and fifty weeks of age.


Gastrointestinal ganglioneuromas; brief review with report of a duodenal ganglioneuroma.


A cyst in the primordium of the tricuspid valve of an abnormal human embryo.


Alkaloidal plants of the apocynaceae.

Alkaloidal plants of the apocynaceae.


The future of physical medicine. VIII. An editorial; research problems in peripheral circulation.


DRUG INFORMATION sources; Yugoslavia, Turkey, Israel, Egypt.


Braces and brace management.

Braces and brace management.


The mechanics of standing on the toes.

The mechanics of standing on the toes.


Simple graded sweat test for the measurement of intense sweating.


Histopathologic reactions of the yolk sac tissue of embryonated hen's eggs to Coccidioides immitis.


Physical medicine management of thoracic surgery patients.


Electrical sensing and recording techniques in biophysics and medicine. II. Review of some sensing and recording applications in human and animal physiology.


Acute glomerulonephritis; a histopathologic study by means of thin sections.


Certain endocrine aspects of the anemia of pregnancy in the rabbit.


Role of pituitary, adrenal and kidney in several thyroid responses of cold-exposed hamsters.


Inverse conditioning by hypohysectomy of mineralocorticoid and glucocorticoid activities of 9[alpha]-chlorocortisol.


Biliary excretion and metabolism of radioactive l-triiodothyronine.


Myotrophic effects of castration and testosterone in thyroidectomized guinea pigs.


Effect of adrenalectomy on ethanol and fat metabolism in the rat.


Studies on hepatitis in hamsters infected with equine abortion virus. II. Changes in protein, nucleic acid, and weight of isolated hepatic nuclei.


In vivo metabolism of fatty acids by adipose and liver tissue of the adrenalectomized rat.


In vivo observation on the seminal vesicles of adult neonatally castrated rats before and after intravenous testosterone.


Influence of a protein-free diet on the immediate and latent effects of stilbestrol.


Glucose-6-phosphate in estronase enzyme systems.


Effect of hypertension on arterial wall electrolytes during desoxycorticosterone administration.


Distribution of infused estrone in human plasma.


Vascular changes in the cheek pouch of adrenalectomized, cortisone-sustained and cortisone-treated hamsters as determined by electrical impedance plethysmography.


CO2 output and energy balance of hereditary obese mice.


Role of serotonin in blood coagulation.

Role of serotonin in blood coagulation.


Effect of prolonged cold exposure on hepatic lipogenesis.


Metabolic response of dogs to hypoxia in the absence of circulating epinephrine and norepinephrine.


Some biokinetic aspects of calcium metabolism in diary cows.


Combination of insulin with frog skeletal muscle.


Postseparation recovery from parabiosis intoxication in the rat.


Vascular responses to local cold injury.


Effect of inositol and rapid rewarming on extent of tissue damage due to cold injury.


Conditioning of rats to tumbling trauma by electroconvulsive shock.


Extensibility of skeletal muscle undergoing reinnervation.


Analysis of forced circling induced by DFP and ablation of cerebral structures.


Summation of potentials in the chicken electroretinogram.


Phagocytosis of foreign red blood cells by the reticulo-endothelial system.


Generation of prothrombin activity with mitochondria or with cathepsin.


Histidine decarboxylase of rat stomach and other mammalian tissues.


Absorption of monoglycerides.

Absorption of monoglycerides.


Effects of low O2 on intestinal blood flow, tonus and motility.


Renal metabolism of 5-hydroxyindolacetic acid.


Effects of prolonged administration of diamox on excretion of acid and carbonic anhydrase and glutaminase activities in the kidney.


Increased renal reabsorption of osmotically free water by the toad (Bufo marinus) in response to neurohypophysial hormones.


Defect in the renal tubular reabsorption of water associated with potassium depletion in rats.


Effect of bilateral cervical vagotomy in the dog.


Measurement of blood volumes in the splanchnic bed of the dog.


Effects of 1-epinephrine and 1-norepinephrine on the splanchnic bed of intact dogs.


Relationships among stroke work, contractile force and fiber length during changes in ventricular function.


Ventricular excitability and refractoriness in the hypothermic dog.


Electric potentials across the aorta of dogs.


Ventricular excitability in the unanesthetized dog and its modification by pentobarbital anesthesia.


Serum potassium concentration and use of ouabain in experimental tourniquet shock.


Effects of adrenergic and cholinergic drugs on splenic inflow and outflow before and during adrenergic blockade.


Venous return at various right atrial pressures and the normal venous return curve.


Liver function changes in hemorrhagic hypotension.


Isolation of platelet cofactor I from plasma and some properties of the preparation.


Phospholipid antithromboplastin; assay in vitro and evaluation in vivo of purified fractions.


Biphasic hyperferremia induced in rats by x-irradiation.


Effect of dose rate on iron incorporation into newly formed erythrocytes of rats exposed to gamma radiation.


Changes in blood, plasma and red cell volume in the male rat, as a function of age.


Erythropoietic response to hypoxia as a function of age in the normal male rat.


Radioiron time-distribution studies at various ages in the normal male rat.


Microscopic studies of skin blood vessels in relation to sympathetic nerve stimulation.


Fixed coupling and short P-R interval induced in the dog by stimulation of the sympathetic nervous system.


Pulmonary blood volume of the dog and its changes in acute heart failure.


Systemic and coronary pressure-flow relationship during total body perfusion in the dog.


Role of the gonads in control of blood pressure in chickens.


Hypothermic myocardial oxygenation.

Hypothermic myocardial oxygenation.


Potassium exchange in atrial fibrillation.


Selective depletion of rat aorta potassium by small pressor doses of norepinephrine.


Aorta and smooth muscle electrolytes during early and late hypertension.


Effects of spinal anesthesia and adrenalectomy on blood pressure responses to histamine.


Effect of pitressin on the isolated perfused rabbit heart.


Development of tolerance to ozone in reference to pulmonary edema.


Characterization of the acute pulmonary edema that follows vagal section in the guinea pig.


Alterations in enzymes and metabolites resulting from adaptation to low oxygen tensions.


Tissue pigment manifestations of adaptation to high altitudes.


Direct effects of adrenal cortical steroids on the electrolyte content of rabbit leucocytes.


Factors influencing the gastric secretion of dyes.


Effect of Egyptian black snake toxin on histamine of blood and its relation to blood eosinophils.


Renal functions in the chimpanzee.

Renal functions in the chimpanzee.


Effect of hypophysectomy and subsequent administration of growth hormone and ACTH on serum proteins of dogs.


Influence of dietary protein and cortisone acetate on adrenalectomized rats.


Effect of fasting on protein release by liver slices.


Water metabolism of the domestic fowl from hatching to maturity.


Effect of certain steroids on metabolic rate of hyperthyroid rats.


Radiophosphorus measurement of the lifespan of lymphocytes in the rabbit.


Effect of age on radiosodium exchange in bone (rat).


Effects of oxygen at high pressure on the transport of potassium, sodium and glutamate in guinea pig brain cortex.


Effects of oxygen at high pressure on the transport of potassium, sodium and alpha-ketoglutarate in guinea pig kidney cortex.


Sodium, potassium and glutamate content of guinea pig brain following exposure to oxygen at high pressure.


Rate of metabolism of ethanol in the mouse.


Effects of carbon dioxide on deep structures of temporal lobe of the brain in the marsupial phalanger.


Lipogenesis from carbohydrate in the negative caloric balance state induced by exposure to cold.


Lipid and cholesterol content of hepatic lymph in experimental nephrosis.


Effect of tumbling trauma on in vivo acetate-2-C14 metabolism in rats.


Capillary permeability to macromolecules: stretched pore phenomenon.


Diffusion of aldolase from rat skeletal muscle; an index of membrane permeability.


Membrane potentials in normal, isolated, perfused frog hearts.


Aldolase activity of the heart and skeletal muscle of exercised rats.


Oxygen consumption of liver following subtotal hepatectomy of normal and hypothyroid rats.


Role of pancreatic digestion in cholesterol absorption.


Response of the chronic gastric fistula rat to histamine.


Effect of fasting on liver enzymes involved in glucose-6-phosphate utilization.


Effects of hypophysectomy on daily temperature variation in C3H mice.


Effects of epinephrine on carbohydrate metabolism in underfed and ad libitum-fed rats.


Role of adrenaline and noradrenaline in chemical regulation of heat production.


Role of the sympathetic nervous system in the control of chemical regulation of heat production.


Effects of gastroenterostomy and of pyrogen on Mann-Williamson ulcer.


Actions of diethylstilbestrol in the albino rat.


Adrenal cortical activity in scorbutic monkeys and guinea pigs.


In vitro metabolism of hydrocortisone in tissues of the adult rat.


Stress and the thymus.

Stress and the thymus.


Protective effect of a sucrose diet in mercuric chloride poisoning.


Effect of intraperitoneal serum albumin on the excretion and renal localization of mercury after mercuric chloride injection in rats.


Freezing and freeze-drying of bull spermatozoa.


Volume and electrolyte homeostasis during antidiuresis.


Age changes in the urinary histamine excretion of rats.


Protein-bound sterols in rodent urine.

Protein-bound sterols in rodent urine.


Proteolytic activity of guinea pig serum activated by streptokinase-human plasminogen preparations.


Plasma concentration of epinephrine and norepinephrine in hemorrhagic and anaphylactic shock.


Cardiovascular functions under chloralose-urethane and 21-hydroxypregnane-3, 20-dione sodium succinate (viadril).


Circulation and blood pressure in the great vessels and heart of the turtle (Chelydra serpentina).


Erythrocyte survival and blood volume in the rat as determined by labeling the red cells with Cr 51.


Failure of the bulbar inhibitory reticular formation to affect somatic reflex activity in the unanesthetized cat.


Organization of central respiratory mechanisms in the brain stem of the cat: genesis of normal respiratory rhythmicity.


Organization of central respiratory mechanisms in the brain stem of the cat: localization by stimulation and destruction.


Localization of spontaneous respiratory neuronal activities in the medulla oblongata of the cat: a new location of the expiratory center.


Pulmonary ventilation studies on pontile and medullary cats; changes on O2 consumption, in arterial blood pH, CO2 tension and O2 saturation, and in response to CO2 and cyanide.


Respiratory response of anesthetized dogs to progressive anemic hypoxia.


Effect of severe hypoxia on blood-cerebrospinal fluid barrier.


Excitation and conduction in immature nerve fibers of the developing chick.


Alterations in metabolism during electrical excitation of frog nerve.


Anodal excitation of cardiac muscle.

Anodal excitation of cardiac muscle.


The evaluation of the effects of derivatives of Rauwolfia in the treatment of schizophrenia.


A biochemical evaluation of the activity of certain tranquilizers and their relationship to hormonal function.


The physiologic basis of the manic-depressive illness: a theory.


Studies in human ecology; factors relevant to the occurrence of bodily illness and disturbances in mood, thought and behavior in three homogeneous population groups.


Some interrelations of social factors and clinical diagnosis in attempted suicide: a study of 109 patients.


Bromide intoxication and quantitative determination in serum.


Two-year fate study of thorazine-treated patients.


The intrafamilial environment of schizophrenic patients. II. Marital schism and marital skew.


The physician and testamentary capacity.


Use of Miltown (meprobamate) with psychotic patients.


The effect of a special diet on hospitalized schizophrenic patients.


Mepazine (pacatal); further report.

Mepazine (pacatal); further report.


Serum lipoprotein concentrations in a schizophrenic population.


Alan Gregg; 1890-1957.

Alan Gregg; 1890-1957.


Eugen Bleuler and present-day psychiatry.


Response to fellowship lecture on Eugen Bleuler.


Murder by adolescents with obscure motivation.


The unlocking of wards in mental hospitals.


A study of the effects of L.S.D.: physiologic and psychological changes and their interrelations.


Therapeutic and toxic effects of chlorpromazine among 3,-14 hospitalized cases.


The antidotal action of sodium succinate in the mescaline psychosis.


The place of reserpine in the treatment of the chronic psychotic patient.


Chronic psychosis following epilepsy.

Chronic psychosis following epilepsy.


A study of the transfer of long-hospitalized patients to a convalescent service.


Effective utilization of electric convulsive treatment.


I remember C. K. Clarke, 1857-1957.

I remember C. K. Clarke, 1857-1957.


A comparison of phenaglycodol (ultran), meprobamate and a placebo in abstinent alcoholics.


Unexpected asphyxial death and tranquilizing drugs.


Sensory deprivation; a review.

Sensory deprivation; a review.


Mycotic nature of brain damage in mental deficiency.


The mecholyl test as a predictor of improvement in insulin coma therapy.


Interaction of the effects of cues involved in judgments of curvature.


The effects of assimilation and contrast in judgments of clinical materials.


Inter-eye differences in color-perception.


Empty-field myopia and visibility of distant objects at high altitudes.


The influence of figural inspection on the autokinetic illusion.


Spatial and textural characteristics of the Ganzfeld.


Certain relations among experienced contingencies, associative structure, and contingencies in encoded messages.


Effect of shock-cessation as an incidental reward in verbal learning.


An analysis of a form of the water jar test.


A confidence scale defined in terms of expected percentages.


Subliminal stimulation in problem-solving.


Verbal and instrumental response-hierarchies and their relationship to problem-solving.


Association of nonsense-figures as a function of fittingness and intention to learn.


The effect of different amounts of alternating partial reinforcement on resistance to extinction.


Constant-current sine-wave circuits for stimulation.


A voice-or sound-key.

A voice-or sound-key.


An inexpensive respirator for use with small animals.


An hypothesis of psychological aging.

An hypothesis of psychological aging.


Dark-adaptation and conditioning; some observed correlations.


Karen's study of incidental learning as a function of meaningfulness.


Index of means vs. mean of indices.

Index of means vs. mean of indices.


Lewis Madison Terman: 1877-1956.

Lewis Madison Terman: 1877-1956.


Guessing and knowing; what makes the difference? A tribute to a statistician; Hilda Freeman Silverman.


C. E. A. Winslow: an appreciation of a great statesman.


The etiology and epidemiology of schizophrenia.


We do not work alone.

We do not work alone.


Some observations on infective diseases in Russia.


Food poisoning outbreaks associated with spray-dried milk; an epidemiologic study.


A study of bacterial flora in swimming pool water treated with high-free residual chlorine.


Industrial and community services promote family health. I. A plan for action.


Industrial & community services promote family health. II. Let us dovetail community & industrial health services.


Industrial & community services promote family health. III. Role of industrial health services in promoting family health.


Industrial & community services promote family health. IV. Adapting health education technics to industrial realities.


Enrollment and placement of health education majors.


Household survey, individual interview, and clinical examination to determine prevalance of heart disease.


Influenza 1957.

Influenza 1957.


How much control of tuberculosis: 1937-1957-1977.


Future explorations in mental health and disease.


Epidemiology of reading disabilities; some methodologic considerations and early findings.


Development of the National Water Supply and Sanitation Program in India.


High school health service problems as the school doctor sees them.


The School Health Program in Puerto Rico.


Action research as a method in public health education.


Physicians' views on the level of medical information among patients.


Problems of participation of the family physician in medical group practice.


Continuous recording of fluoride in water.


A diet instruction service for private parents; a pilot study.


PREDICTION and theory in epidemiology.

PREDICTION and theory in epidemiology.


NURSING in the training of public health workers.


PROPOSED statement on poultry inspection.


Cooley's anemia: a review of the roentgenographic findings in the skeleton: Hickey lecture, 1957.


Hypophosphatasia.

Hypophosphatasia.


Neuroblastoma: a roentgenologic and pathologic study.


Metastatic retinoblastoma as a cause of diffuse intracranial calcification.


Roentgen appearances of the lungs in 1,000 apparently normal full term newborn infants.


Roentgenographic findings in hyaline membrane disease in infants weighing 2,000 grams and over.


Roentgen standards fo-size of the pituitary fossa from infancy through adolescence.


Primary pulmonary hypertension in brothers.


The effect of prolonged nutritive failure on epiphyseal fusion in the human hand skeleton.


Gas in the fetal blood stream; a useful sign of fetal death.


Chondroangiopathia calcarea seu punctata (chondrodystrophia calcificans congenita): an atypical, stationary form of the disease.


Premature growth arrest of the knee epiphyses.


Eosinophilic granuloma of bone.

Eosinophilic granuloma of bone.


Congenital superior ectopia of the kidney.


Lead poisoning during infancy and early childhood.


Histopathology of roentgen death of young axolotl (Siredon mexicanum).


Esophageal webs.

Esophageal webs.


Significance of regional or reflex ileus in the roentgen diagnosis of cholecystitis, perforated ulcer, pancreatitis and appendiceal abscess, as determined by survey examination of the acute abdomen.


Spontaneous rupture of esophagus with emphasis on the roentgenologic diagnosis.


The association of volvulus of the cecum and ascending colon with other obstructive colonic lesions.


Diffuse calcification of the pancreas.

Diffuse calcification of the pancreas.


The nonvisualizing and poorly visualizing gallbladder.


Simulation of colonic obstruction at the splenic flexure by pancreatitis: roentgen features.


Intragastric gallstone.

Intragastric gallstone.


The biliary tract in the normal and cholecystectomized patient.


Postoperative diaphragmatic hernia: a complication of hiatus hernia repair; report on two cases.


Gastrointestinal manifestations of the Schönlein-Hen och syndrome; roentgenologic findings.


Enteroliths complicating regional enteritis; a report of two cases.


Ileocecal intussusception in the adult.

Ileocecal intussusception in the adult.


Diverticula of the appendix; a case observation.


Pneumatosis cystoides intestinalis; report of the first case complicated by fatal rupture of the colon.


The roentgenologic detection of small rectal polyps; a contribution to the prophylaxis of carcinoma of the rectum.


A variant of the pseudotumor sign.

A variant of the pseudotumor sign.


The use of water soluble contrast medium (hypaque) for gastrointestinal roentgenography.


Detection of gastrointestinal bleeding with a barium-hydrogen peroxide mixture.


The use of radioactive isotopes in the evaluation of gastrointestinal function.


Hepatography.

Hepatography.


Renal Escherichia coll infection associated with diabetes mellitus.


Use of senna for preparation of the colon for roentgen examination.


Public relations and educational programs of the American College of Radiology.


Joseph M. Foley; 1899-1957.

Joseph M. Foley; 1899-1957.


Fatal trauma as seen in suburban hospitals.


Cancer of the esophagus; surgical experience in 101 resections from 1948 to 1955.


Primary esophagogastrectomy for instrumental perforation of the esophagus.


Surgical wound infections.

Surgical wound infections.


Erythromycin and erythromycin-neomycin for intestinal antisepsis.


Pheochromocytoma in children; review of significant surgical aspects and report of three additional cases.


Struma lymphomatosa (Hashimoto's disease) in children.


Fibrosarcoma of bone.

Fibrosarcoma of bone.


Ureteral injuries in pelvic surgery.

Ureteral injuries in pelvic surgery.


A study of cigarette smoke and cigarette paper smoke alone.


The treatment of operable carcinoma of the breast.


The problem of carcinoma of the tongue in India.


Mediastinal teratoma simulating adenomatous goiter.


Automobile collision with simultaneous bilateral dislocation of the hip.


Fractures of the anterior process of the calcaneus.


Pneumatosis cystoides intestinalis diagnosed sigmoidoscopically; report of case and review of literature.


Lumbar sympathectomy for peripheral arteriosclerosis.


A comparison of antibiotic concentrations in plasma and muscle.


Surgical technic of tracheal fenestration.


Umbilical transplantation upward and abdominal contouring in lipectomy.


Extramammary Paget's disease.

Extramammary Paget's disease.


Bifid blind-ending ureter.

Bifid blind-ending ureter.


Neonatal tumors of the kidney.

Neonatal tumors of the kidney.


Kidney stone expelled through skin below healed lumbar incision.


Adenomatoid tumor of the epididymis; a review and report of two additional cases.


Recurrent laryngeal nerve paralysis occurring in an infant.


Decompression of the spinal cord in Pott's paraplegia.


Dislocation of the clavicle below the acromion.


Pulmonary valvular stenosis.

Pulmonary valvular stenosis.


Malignant leiomyoma of the jejunum.

Malignant leiomyoma of the jejunum.


Free perforation of a jejunal ulcer following vagotomy and gastroenterostomy.


Whiplash injury and liability.

Whiplash injury and liability.


Postoperative edema in maxillofacial surgery; prevention and treatment with promethazine.


The role of ascaris lumbricoides in intestinal perforations.


Primary Hodgkin's disease of the stomach.


Primary lymphosarcomas of the stomach; report of seven cases.


The diagnosis and management of acute pancreatitis.


Foreign body perforation of the intestinal tract.


Cancer of the colon, rectum and anal canal; surgical approach with rates of five- and ten-year survival.


Repair of the incontinent sphincter ani.


Elective resection for sigmoidal diverticulitis.


Primary reticulum cell sarcoma of bone; a presentation of five cases.


A practical approach to the management of delayed union and non-union of the long bones.


Fractures of the os calcis.

Fractures of the os calcis.


Local anesthesia for the aged and poor risk patient with fracture of the hip; 137 consecutive operations.


The management of anesthesia for adrenalectomy.


The prevention of postoperative pulmonary complications.


The suprarenal veins.

The suprarenal veins.


Acute pancreatitis associated with acute cholecystitis; the curative value of biliary tract surgery.


Vaginal plastic surgery based on a new concept of the anatomy of the female genital tract. III. Birth injuries to the posterior vaginal wall.


Chronic extradural hematoma.

Chronic extradural hematoma.


Excision of acute pilonidal cyst abscess; a preliminary report.


Meckel's diverticulum as a source of hemorrhage.


Aneurysm of the renal artery.

Aneurysm of the renal artery.


Carotid body tumor; report of case treated by resection of tumor and carotid artery followed by replacement of artery with frozen dried graft.


Laceration of popliteal artery due to blunt trauma.


Ilioinguinal swellings.

Ilioinguinal swellings.


Total reconstruction of an ear.

Total reconstruction of an ear.


Spontaneous rupture of the esophagus.

Spontaneous rupture of the esophagus.


Perforation of Meckel's diverticulum by foreign body.


True diverticulum of the prepyloric area of the stomach.


Torsion of an intra-abdominal testicle.

Torsion of an intra-abdominal testicle.


Littre's hernia.

Littre's hernia.


New biopsy needle; report on auger type instrument for obtaining tissue specimens.


A vise-retractor for mid-thigh amputations.


A practical philosophy of vector control in the U.S.A.


Further studies on malaria suppression by monthly drug administration.


Anopheles gambiae in relation to malaria and filariasis in coastal Liberia.


Resistance of Plasmodium malariae to pyrimethamine (daraprim).


Studies on malaria in chimpanzees. IV. Plasmodium ovale.


The effect of penicillin G on two strains of small race Entamoeba histolytica in culture.


Chemotherapy of Trypanosoma gambiense and Trypanosoma rhodesiense infections in guinea pigs with nitrofurazone.


Nitrofurazone therapy of Trypanosoma gambiense sleeping sickness in man.


Reactions to chloroquine observed during the treatment of various dermatologic disorders.


Efficacy of amodiaquin hydrochloride (camoquin hydrochloride) against giardiasis.


Isolation of Ilhéus virus from Sabethes chloropterus captured in Guatemala in 1956.


Isolation of yellow fever virus from Haemagogus lucifer, H. equinus, H. spegazzinii falco, Sabethes chloropterus and Anopheles neivai captured in Panama in the fall of 1956.


The isolation of St. Louis virus from a nestling bird in Trinidad, British West Indies.


The isolation of St. Louis virus from Trinidad mosquitoes.


Antibodies to poliomyelitis virus and socioeconomic factors influencing their frequency in children in Israel.


Note on antibodies to poliomyelitis viruses in the sera of residents of Eastern Saudi Arabia.


Studies on Pasteurella pestis in fleas. VI. The laboratory culture of Xenopsylla vexabilis hawaiiensis Jordan, 1932.


A survey of Schistosoma haematobium infections in man in Liberia.


Distribution and prevalence of human schistosomiasis in Puerto Rico in 1953.


Serodiagnosis of schistosomiasis: specificity of the complement-fixation test in other helminthic infections.


Rare histopathologic aspects of Manson's schistosomiasis.


Bancroftian filariasis in the etiology of funiculoepididymitis, periorchitis and hydrocele in Puerto Rico (statistical study of surgical and autopsy material over a 13-year period).


The asthma-gram; a diagnostic approach to asthma.


On the incidence of poisonous snakebites in Florida: analysis of 241 cases occurring during 1954 and 1955.


Flea-host relationships of associated Rattus and native wild rodents in the San Francisco Bay area of California, with special reference to plague.


Cardiac competence.

Cardiac competence.


An approach to the complexity of cor pulmonale.


Pentolinium-meprobamate therapy the older patient with hypertension.


Management of the emotional factor in the practice of internal medicine.


The general practitioner and psychosomatic medicine.


Inflammatory diseases--vulval and vaginal; treatment with hydrocortisone vaginal suppositories.


Pruritus ani; treatment with tar extract hydrocortisone cream.


Experiences with promazine in daily practice; report of 77 diverse cases.


Acetaminophen; a new antipyretic-analgesic for pediatric use.


Morbid conscientiousness.

Morbid conscientiousness.


On taping the chest.

On taping the chest.


Roentgenographic patterns in histoplasmosis.


Acute respiratory effects of pneumothorax in normal and vagotomized dogs.


Antituberculous therapy in Macaca mulatta monkeys.


The prevalence of tuberculin sensitivity and its relation to a BCG vaccination program among Chinese in Hong Kong.


Some relationships between personality and behavior in hospitalized tuberculous patients.


Proteins and mucoproteins in pleural effusions.


Preliminary experiments on passive transfer of protective humoral antibodies in tuberculosis.


Effect of isoniazid and cortisone in children vaccinated with BCG.


Novobiocin: activity in vitro and in experimental tuberculosis.


Surface alteration studies of Mycobacterium tuberculosis with trypsin.


Pulmonary geotrichosis.

Pulmonary geotrichosis.


Roentgenotherapy of the middle lobe syndrome in children; report of two cases.


The relationship between drug resistance and the growth phase of Mycobacterium avium.


The decrease of mutation rate to streptomycin resistance in sulfathiazole-resistant Mycobacterium avium produced by the presence of sulfathiazole; a specific effect of sulfathiazole in reducing the emergence of streptomycin resistance by a nonselective mechanism.


Tuberculous infection during academic studies.


The evaluation of the egg embryo as a laboratory procedure for the rapid detection of the tubercle Bacillus.


The vital capacity in bronchospirometry.


Chemotherapy of tuberculosis. I. Antituberculous activity of verazide and related hydrazones.


Chemotherapy of tuberculosis. II. Some observations on the pharmacology of verazide.


Pathogenesis and treatment of pulmonary tension cavities.


U. S. Veterans Administration-Armed Forces Cooperative Studies of tuberculosis. VI. Survival among patients with miliary and meningeal tuberculosis (1948-1955).


Primary tuberculosis in infants and young children; survey of a slum area in Puerto Rico.


The long-term effects of exposure to nitrous fumes.


Hepatic derangement in pulmonary tuberculosis.


Rapid test of virulence of Mycobacterium tuberculosis by inoculation of cisterna magna of guinea pigs.


Cultural characteristics and drug and bacteriophage resistance of avian tubercle bacilli.


Characterization of atypical mycobacteria and of Nocardia species isolated from clinical specimens. I. Characterization of atypical mycobacteria by means of the microcolonial test.


Characterization of atypical mycobacteria and of Nocardia species isolated from clinical specimens. II. Procedure for differentiating between acid-fast microorganisms.


Achalasia (mega-esophagus); a condition capable of simulating mediastinal neoplasm.


The limitations of our knowledge about para-aminosalicylic acid.


Drug susceptibilities of 20 atypical as compared with 19 selected strains of mycobacteria.


Scalene lymphadenopathy; a post-mortem study.


Cardiac stab wounds.

Cardiac stab wounds.


Experiences with aortic dissecting aneurysms.


Carotid-cavernous arteriovenous aneurysm.


Peripheral arterial embolism.

Peripheral arterial embolism.


Thrombosis of the vena cava to the level of the renal veins with recovery.


Mesenteric thrombosis.

Mesenteric thrombosis.


Early management of the pleural space following partial pulmonary resection.


Aberrant pancreatic tissue in gastric wall; report of four cases simulating peptic ulcer.


Splenectomy, thrombocytosis, and venous thrombosis.


Familial polyposis of the colon: the fate of the retained rectum after colectomy in children.


Duodenal injury due to nonpenetrating abdominal trauma.


The four dimensions of surgery.

The four dimensions of surgery.


The value of employment of the component parts of the transversalis fascia and Cooper's ligament in the repair of the large oblique, direct and recurrent inguinal hernia.


A photographic study of the superior and inferior laryngeal nerves and the superior and inferior thyroid arteries.


Tissue necrosis associated with intravenous nor-epinephrine administration.


Causalgia.

Causalgia.


Sigmoid volvulus initiated by anal fissure.


Treatment of acute intestinal obstructions.


Tracheotomy: a clinical and experimental study. I.


Studies on the effect of cortisone on specific gastrointestinal functions: the systemic response to injury.


Electrographic monitoring of anaesthesia; a method for experimental and clinical study of reversal of barbiturate narcosis.


Phlebotomy; its surgical and anaesthetic uses.


Chlorpromazine; effect on blood volume, venous pressure and circulation time estimations.


Halothane; a report on its use in twenty-five selected cases of pulmonary or cardiac disease.


Intramuscular lignocaine; an adjuvant to nitrous oxide-oxygen anaesthesia.


Anaesthesia for Rammstedt's operation.

Anaesthesia for Rammstedt's operation.


Balanced anaesthesia for Caesarean section; a review of 614 cases (1948-1956).


Crush injury of the chest; a report on two cases.


Sub-total spinal analgesia.

Sub-total spinal analgesia.


Incidence of thrombosis following thiopentone.


The anaesthetic triangle.

The anaesthetic triangle.


Anaesthesia in Switzerland.

Anaesthesia in Switzerland.


Modified bronchoscope for endobronchial intubation.


[Comparative study of proteins in cerebrospinal fluid & blood serum in tuberculous meningitis; electrophoretic technic].


Regional variations in the innervation of deep fasciae and aponeuroses.


Anatomical corrosion specimens. I. Heart-lung models prepared from dogs.


Histogenesis and histochemistry of the digestive tract of chick embryos.


Anatomical corrosion specimens. II. Bronchopulmonary anatomy in the dog.


The radiomimetic effect of neotetrazolium chloride on the skin of mice.


Abnormalities of the urinary system of rat embryos resulting from transitory deficiency of pteroylglutamic acid during gestation.


Loss of clear cells in the hair follicles of x-irradiated albino mice.


Regulation of blood flow through the stomach of the rat.


Robert Russell Bensley, 1867-1956.

Robert Russell Bensley, 1867-1956.


An abnormal saphenofemoral junction.

An abnormal saphenofemoral junction.


Pathways of absorption of protein from the cerebrospinal fluid: an autoradiographic study in the cat.


Correlations of certain ponderal and linear skeletal measurements with skull' weight and skull length in the opossum.


A study of the mechanism of keratinization of human epidermal cells.


A correlative anatomical and functional study of the dorsolateral prostate of the rat.


Morphological evidence of a possible functional interrelationship between the median eminence and the pars distalis of the anuran hypophysis.


Submicroscopic structure of frozen-dried liver specifically stained for electron microscopy.


Fiber components of the splanchnic nerves.


The origin of reticulospinal fibers in the cat; an experimental study.


Natural occurrence and artificial induction of parthenogenetic cleavage of ferret ova.


Submicroscopic structure of frozen-dried liver specifically stained for electron microscopy. II. Biological.


The rubrobulbar tract: anatomical relationships, course, and terminations in the rhesus monkey.


Histological and histochemical studies on the homozygous Creeper embryo.


The injection of the blood vascular system of the uterus.


Presence of the pituitary in perfect cyclopia.


Progressive cytological changes in the hypophysis associated with endocrine interaction following exposure to cold.


Electron microscopic identification of different cell types in the islets of Langerhans of the guinea pig, rat, rabbit and dog.


Robert Payne Bigelow; 1863-1955.

Robert Payne Bigelow; 1863-1955.


George Bain Jenkins; 1874-1956.

George Bain Jenkins; 1874-1956.


Albert Kuntz; March 19, 1879-January 19, 1957.


Cleveland Sylvester Simkins; 1889-1956.

Cleveland Sylvester Simkins; 1889-1956.


The fine structure of brown adipose tissue in the rat with observations on the cytological changes following starvation and adrenalectomy.


Eventration of the abdominal viscera associated with umbilical hernia, hemipenes and hydromyelomeningocele in a newborn infant.


The sacral levels contributing afferent fibers to the feline pelvic and pudendal nerves; verification by silver impregnation of degenerating axons after dorsal root ganglionectomy.


The effect of age, sex, and body size on the heart weight-body weight ratio in the dog.


Gonadal effects upon the growth of pituitary, adrenals, thyroids, oviduct, and comb of immature fowl.


Cytological aspects of mouse and rat liver containing nuclear inclusions.


Quantitative studies of phagocytosis by means of thorotrast.


The pelvis of the rat: its response to estrogen and relaxin.


Studies in extracorporeal circulation. V. Anesthesia and supportive care during intracardiac surgery with the Gibbon-type pump-oxygenator.


Roentgenographic studies of the oropharyngeal airway.


Studies of analgesic drugs: anileridine dihydrochloride.


Effects of anesthesia on thyroid function of rats.


The effect of beta, beta-methylethylglutarimide (megimide) and thiopental in dogs.


Peridural block: analysis of 3,637 cases and a review.


Bradycardia following intravenous administration of succinylcholine chloride to infants and children.


The effects of promethazine upon respiration and circulation of man.


The prevention of claims for malpractice.


A ride through Central Park.

A ride through Central Park.


Pediatric circle absorber.

Pediatric circle absorber.


Femoral artery reconstruction.

Femoral artery reconstruction.


[Experience with treatment of diabetes by D-860; 150 patients].


Observations on the structure of the bronchial wall in bronchiectasis.


Urinary excretion of radio-vitamin B-12 in pernicious tapeworm anaemia.


The effect of operations on the excretion of total 17-hydroxycorticosteroids in elderly patients.


Effect of short-term administration of l'-triiodothyronine in hypometabolism.


Roentgenological changes of the cervical spine in elderly patients with postural dizziness.


Serial studies of serum lipids and lipoproteins in acute myocardial infarction.


Fatal idiopathic myocarditis with collagenous vascular changes; a case report and autopsy observations.


Essential hyperlipaemia and atherosclerosis; a case report.


Effect of carbonic anhydrase inhibitor on gastric mucosa and pancreas as revealed by histochemically demonstrable succinic dehydrogenase activity.


[Pigmentary glaucoma].

[Pigmentary glaucoma].


Studies on malaria in chimpanzees. III. Gametogony of Plasmodium reichenowi.


Anomalous pulmonary venous drainage of right lung into inferior vena cava with malrotation of the heart: report of three cases.


The safety of intravascular carbon dioxide and its use for roentgenologic visualization of intracardiac structures.


The varied clinical manifestations of pulmonary embolism.


Observations in the treatment of hyperthyroidism with I131.


Disability two to five years after mitral commissurotomy: an evaluation by clinical criteria and exercise tolerance.


Studies of B12Co60 absorption in malabsorption syndrome: results before and during specific therapy.


Chronic sodium chloride toxicity: the protective effect of added potassium chloride.


Studies in Hodgkin's syndrome. XII. Hereditary and epidemiologic espects.


Differentiation of macrocytic anemias and diagnosis of pernicious anemia and sprue in remission by accelerated measurement of hepatic uptake of radioactive Co60B12.


Chronic, disseminated, nonlipoid reticuloendotheliosis (histiocytosis X): treatment with corticotropin and antibiotics, with report of two cases.


Intrahepatic obstructive jaundice following the administration of 75 mg. of chlorpromazine.


Cryptococcus meningitis arrested with amphotericin B.


Probable deficiency of vitamin B12 with pernicious anemia in two patients with normal Schilling test.


Acute pericarditis as the first manifestation of infectious mononucleosis.


Pseudohypoparathyroidism: report of case.


Standards of practice of internal medicine and methods of assessing the quality of practice in hospitals.


Tradition and progress in medicine.

Tradition and progress in medicine.


Fatal bromsulphalein reaction.

Fatal bromsulphalein reaction.


Characteristics of the individual as guideposts to the prevention of heart disease.


Some basic, unsolved problems in the prevention of rheumatic fever.


Carbarsone toxicity: a review of the literature and report of 45 cases.


Hyperuricemia associated with the treatment of acute leukemia.


Sporotrichosis; a report of 12 cases, including two with skeletal involvement.


Pulmonary atelectasis: physical factors.


A clinicopathologic study of chronic renal vein thrombosis in adults.


AGAMMAGLOBULINEMIA: Clinical staff conference at the National Institutes of Health.


Circulatory arrest in patients with complete heart block during anesthesia and surgery.


Fatal polycythemia following pernicious anemia treated with vitamin B12.


Paroxysmal ventricular fibrillation in the absence of other disease.


Peripheral vascular occlusion due to hemorrhage in hemophilia.


Thrombotic thrombocytopenic purpura (Moschcowitz's disease): report of a case with remission after splenectomy and steroid therapy.


Treatment of leukemia cutis with demecolcin.


Subacute bacterial endocarditis occurring in a patient receiving oral penicillin as prophylaxis against rheumatic fever.


Extracellular hyperosmolarity secondary to high protein nasogastric tube feeding.


Pancreatic insufficiency and hyperparathyroidism.


Properdin.

Properdin.


The history of tension.

The history of tension.


Meprobamate and other agents used in mental disturbances; introductory remarks.


The chemistry and mode of action of tranquilizing drugs.


Experimental studies of behavioral effects of meprobamate on normal subjects.


Some effects of meprobamate on conditioned fear and emotional behavior.


Effects of meprobamate on imprinting in waterfowl.


Comparative study of the effect of meprobamate on the conditioned response on strychnine and pentylenetetrazol thresholds, on the normal electroencephalogram, and on polysynaptic reflexes.


The effects of ward tension on the quality and quantity of tranquilizer utilization.


Differential effects of the new psychotropic drugs.


Treatment of anxiety states with meprobamate.


Meprobamate a clinical evaluation.

Meprobamate a clinical evaluation.


Electromyographic studies on meprobamate and the working, anxious patient.


Meprobamate in chronic psychiatric patients.


Meprobamate in senile psychosis.

Meprobamate in senile psychosis.


The role of meprobamate in postoperative surgical care.


An evaluation of meprobamate in the treatment of alcoholism.


The treatment of chronic headache with meprobamate.


Clinical evaluation of meprobamate in disturbed and prepsychotic children.


The value of muscle relaxants in disorders of muscle tone.


The use of meprobamate and other muscle relaxants in muscle spasm due to rheumatic conditions.


The use of meprobamate in the treatment of skeletal muscle spasm.


The effect of meprobamate on cerebral palsy.


The effect of meprobamate on the basal ganglia.


Meprobamate and other agents used in mental disturbances; concluding remarks.


THE ELECTROPHYSIOLOGY of the heart.

THE ELECTROPHYSIOLOGY of the heart.


Beyond membrane potentials.

Beyond membrane potentials.


Resting and action potentials of cardiac muscle.


Some molecular aspects of heart behavior.


Effects of sodium and potassium on repolarization in frog ventricular fibers.


The pulsatile nature of the release of potassium from heart muscle during the systole.


Normal and abnormal transmembrane potentials of the spontaneously beating heart.


Current problems of excitation.

Current problems of excitation.


The general order of excitation and of recovery.


Ventricular depolarization and the genesis of QRS.


Excitation of the left ventricular wall of the dog and goat.


The activation of the interventricular septum in the dog's heart under normal conditions and in bundle-branch block.


The conducting tissue and cardiac electrophysiology.


ANOMALOUS atrioventricular excitation: panel discussion.


Recovery of cardiac muscle, a particular problem.


The ventricular gradient of Wilson.

The ventricular gradient of Wilson.


The integrated electrocardiogram.

The integrated electrocardiogram.


The presentation of spatial vectorcardiographic data on a linear time scale.


Radioelectrocardiography: a new technique for cardiovascular studies.


Studies on the nature of the repolarization process.


THE REPOLARIZATION process of cardiac musculature: panel discussion.


THE U WAVE and after potentials in cardiac muscle: panel discussion.


The physiological basis of the spread of cardiac action currents through the body.


The spread of currents and distribution of potentials in homogeneous volume conductors.


Spread of current in volume conductors of finite extent.


The potential of a general dipole in a homogeneous conducting prolate spheroid.


The conductivity of living tissues.

The conductivity of living tissues.


Human thorax potentials.

Human thorax potentials.


Experimental and theoretical aspects of vector analysis in electrocardiography.


Lead vector projections. I.

Lead vector projections. I.


Lead vector projections. II. Determination of the image surface in man.


Lead vectors and transfer impedance.

Lead vectors and transfer impedance.


Exploratory lead systems and zero potentials.


The hypoglycemic sulfonamides: history and development of the problem from 1942 to 1955.


Action of the hypoglycemic sulfonyl compounds in hypophysectomized, adrenalectomized, and depancreatized animals.


The role of insulin in the action of the hypoglycemic sulfonyl compounds.


The response of kidney, liver, and peripheral tissues to tolbutamide and insulin.


The effect of tolbutamide on insulin-I131 degradation in the extrahepatic tissues.


Respiratory quotient and nitrogen balance during tolbutamide administration.


Studies on the mechanism of tolbutamide hypoglycemia in animal and human subjects.


Studies of the effect of intravenous tolbutamide on pyruvic and lactic acid concentrations in peripheral venous blood in normal and diabetic subjects, and on splanchnic metabolism of fructose and glucose.


Studies on the site of action of the arylsulfonylureas in man. II.


A concept of the mechanism of sulfonylurea-induced hypoglycemia based on studies of glucose and pentose disposition in man.


The role of insulinase in the hypoglycemic response to sulfonylureas.


Effects of tolbutamide and insulin on fructose and glucose metabolism in diabetes mellitus.


The effect of tolbutamide on glucose production by the liver in vitro.


Studies on the absorption, mechanism of action, and excretion of tolbutamide in the rat.


Perfusion studies with sulfonylureas in dogs.


Studies on the disposition of isotopic glucose in vivo and in vitro under the influence of sulfonylureas.


Functional and histological studies concerning the action of sulfonylureas.


Toxicological and histological studies with tolbutamide.


Reports on studies with carbutamide and tolbutamide done at the Charles H. Best Institute, University of Toronto.


Sex differences in the amount of insulin extractable from diabetic human pancreas.


Long-term studies of the sulfonylureas in totally depancreatized dogs.


Studies concerning the role of the liver in the hypoglycemic response of animals to tolbutamide.


The mechanism of action of the hypoglycemic sulfonamides: a concept based on investigations in animals and in human beings.


Metabolic effects of sulfonylureas in normal men and in various types of diabetic patients.


Effects of tolbutamide on the diabetes of acromegaly and on the blood sugar in patients with altered endocrine states.


Clinical experiences with the sulfonylurea compounds.


Clinical experience with sulfonylurea compounds in diabetes.


The use of tolbutamide in the management of adult diabetes.


Use of the sulfonylureas in diabetes mellitus.


Further experience with the use of sulfonylureas in diabetes.


Thyroid function of diabetic patients as influenced by the sulfonylureas.


Experience with the tolbutamide treatment of five hundred cases of diabetes on an ambulatory basis.


Pathogenesis and treatment of cholesteatoma in chronic suppuration of the temporal bone.


Report on experiences in one and a half years of oral treatment of diabetes with tolbutamide.


The choanal polyp.

The choanal polyp.


Heat and moisture exchange of respiratory mucous membrane.


Observations on the exchange of fluid in the nose and respiratory tract.


Transoral intralaryngeal approach for arytenoidectomy in bilateral vocal cord paralysis with inadequate airway.


Trends in radical frontal sinus surgery.


Anatomical etiological factors in chronic middle ear discharge.


Neurotoxicity of streptomycin and dihydrostreptomycin.


Pure-tone audiometry in children; lantern-slides test.


Applied phoniatrics; speech after removal of the upper jaw; dependence of conservation of function and appearance upon pathology.


Two cases of nonchromaffin paraganglioma in the middle ear.


The goniometer test.

The goniometer test.


The neurology and function of the pharynx, and its powers of compensation in paralysis.


Salivary adenomas of the buccal cavity.

Salivary adenomas of the buccal cavity.


Observations on paralysis of the vocal cords in some of the neurological diseases.


Anomalies in the recorded movements of the eye during optokinetic rotatory and caloric stimulation in normal subjects.


Chronic osteitis of the maxilla in relation to maxillary sinusitis.


Report of a death following acute otitis media.


Microelectrode studies on the auditory nervous system.


Behavioral studies of auditory discrimination.


Structure of the stria vascularis and the spiral prominence.


Experimental obstruction of venous drainage and arterial supply of the inner ear.


Adventures with the stapes.

Adventures with the stapes.


The meatoantrotomy; a special approach for plastic procedures.


Exercise therapy.

Exercise therapy.


Extreme slowing of nerve conduction in peroneal muscular atrophy.


Self-help and the arthritic patient.

Self-help and the arthritic patient.


Treatment of strictures of the ureter by side to side anastomosis.


Exercises for increasing muscle power in cervical spondylosis.


CHESELDEN'S anatomy drawings.

CHESELDEN'S anatomy drawings.


Facial development.

Facial development.


Lord Nelson and the expenses of his cure.


Discrete nodules of the thyroid gland, with special reference to carcinoma.


The management of dysphagia due to malignant disease of the thoracic and abdominal oesophagus.


Hypothermia. III. The effect of hypothermia on renal damage resulting from ischemia.


A new approach to the physiology of so-called cardiospasm: experimental production of cardiospasm in cats after destruction of Auerbach's plexus.


Follow up note on a previously reported patient with surgical closure of patent ductus arteriosus with reversal of flow.


Coarctation of the aorta proximal of the left subclavian artery: experience with six surgical cases.


Cortisone in experimental obstructive jaundice.


Novobiocin and novobiocin-neomycin for intestinal antisepsis.


Effect of total cardiac by-pass on renal hemodynamics and water and electrolyte excretion in man.


Aneurysms of the abdominal aorta and its branches: a study of untreated patients.


Subdural empyemas.

Subdural empyemas.


The use of a long anterior skin flap in radical neck resections.


Further studies on the absorption and equilibration of water (deuterium oxide) from the gastro-intestinal tract.


Evaluation of esophago-jejunostomy in the treatment of lesions at the esophago-gastric junction.


Fatal postoperative pancreatitis.

Fatal postoperative pancreatitis.


Factors in making a small surgical stoma: the difference in the ratio between the circumference and the area in a small stoma as compared to a large one, and its application to the surgery of infancy.


Annular pancreas.

Annular pancreas.


Duodenal varices due to portal hypertension from arteriovenous aneurysm; report of a case.


Spontaneous rupture of the hepatic duct.


Study of factors influencing induced tolerance to skin homografts in the chicken.


A technic for reconstruction of the lower lip following extensive excision for cancer.


Management of large bowel injuries in civilian practice.


The feasibility of ulcer removal: an evaluation of gastroduodenostomy.


Presidential address: A letter to Alastair Crovenay, M.D.


Radiation burns due to atomic explosions.


Reconstruction of electrical injuries, including cranial losses; with preliminary report of cathode-ray burns.


The causes of death from total body irradiation; an analysis of the present status after fifteen years of study.


Effect of thermal burns on wound healing.


Tetanus: evaluation of treatment at Charity Hospital, New Orleans, Louisiana.


The problem of postoperative wound infections caused by Staphylococcus aureus.


Staphylococcal infections of the heart and great vessels due to silk sutures.


Changing diagnostic criteria for hyperparathyroidism.


Carcinoma of the lung: factors which influence five year survival with special reference to blood vessel invasion.


Clinical experiences with induced cardiac arrest during intracardiac surgical procedures.


Problems in the surgical management of thymic tumors.


Coarctation of the aorta in infants and children.


Surgical treatment of ruptured aneurysms of the sinus of Valsalva.


Controlled extracorporeal circulation in surgical treatment of aortic aneurysm.


Special problems in venous thromboembolism.


Attempts to restore function in major veins which are the site of massive thrombosis.


Surgical treatment of atherosclerotic occlusion of the internal carotid artery.


A combined local and systemic treatment of furunculosis.


The solubility of oral preparations of penicillin V.


Preliminary clinical observations on a potential antiemetic agent, proclorperazine (compazine).


The biochemistry of the blood in bronchial asthma.


Antibiotics and the problem of medical communication.


Cycloserine and its value in the treatment of chronic pulmonary tuberculosis.


The diagnosis and management of patients with arterial hypertension: evaluation of five years' experience with surgical procedures and depressor drugs.


Fermentation processes leading to glycerol. I. The influence of certain variables on glycerol formation in the presence of sulfites.


Fermentation processes leading to glycerol. II. Studies on the effect of sulfites on viability, growth, and fermentation of Saccharomyces cerevisiae.


Fermentation processes leading to glycerol. III. Studies on glycerol formation in the presence of alkalis.


Microbiological process discussion; calculation of heat sterilization times for fermentation media.


Aeration of Bacillus anthracis in submerged fermentation.


Microbiological process report: analytical microbiology. III. Turbidimetric methods.


The nonlogarithmic rate of thermal destruction of spores of Bacillus coagulans.


Improved medium for assay of thiamine with Lactobacillus fermenti.


Addition of sugar, amino acids and corn steep liquor to cucumber fermentation.


The effect of medium constituents on penicillin production from natural materials.


Species of Propionibacterium associated with zapatera spoilage of olives.


Production and testing of yeast mutants for glycerol formation.


[Encephalomyocarditis syndrome with involvement of other organs].


[Ebstein's abnormality of the tricuspid valve].


An analysis of the free intracellular amino acids of certain strains of Neurospora.


Saturated fatty acids as bacterial antimetabolites.


The binding of magnesium, calcium, and chlorine ions to heavy and light meromyosin.


Biochemical studies of acute inflammation. I. Chemical changes in the normal animal.


A micro-colorimetric method for the determination of shikimic acid.


Beta-carotene, an active component of chloroplasts.


Some effects of excess methionine on lipide metabolism in the rat.


Calcification in lysine deficiency.

Calcification in lysine deficiency.


Inhibition of the growth of the filamentous fungus, Allomyces macrogynus, by lipoic acid.


Dissociation of macromolecular ribonucleoprotein of yeast.


The hydrolysis of xylan and xylooligosaccharides by ruminal enzymes.


Purification and properties of a proteolytic enzyme from Bacillus stearothermophilus.


The separation of phosphate esters and other metabolites by ionophoresis and chromatography on paper.


A modified reaction vessel for ninhydrin determination of alpha-amino acids.


Respiration studies of a Micrococcus capable of oxidizing hydrocarbons.


Metabolism of cesium-134 in rabbits.

Metabolism of cesium-134 in rabbits.


The effect of x-ray exposure on deoxyribonuclease II activity in lymphoid tissues.


Nutrition and metabolism of marine bacteria. V. The inhibition of growth of a marine bacterium by amino acids and the development of resistant strains.


Properties of substances in gelatin which stimulate the growth of chicks fed amino acid diets.


Protection of bacteriophage T1 against x-rays and heat.


Studies on the primary process in photosynthesis. I. Photosynthetic luminescence; multiple reactants.


Studies on the primary process in photosynthesis. II. Some relationships between light-induced absorption spectrum changes and chemiluminescence during photosynthesis.


The state of plasma albumin in acid pH.

The state of plasma albumin in acid pH.


Variations in the production of carotenoids in Neurospora.


Isolation of an acidic pigment in Neurospora.


Chromatography of horse-radish enzymes; a separation of two acid phosphomonesterases.


Tungstate as an antagonist of molybdate in Azotobacter vinelandii.


Enzymic heterogeneity of crystalline ribonuclease.


Uricase in Neurospora crassa.

Uricase in Neurospora crassa.


Isolation of delta 4-pregnene-11 beta, 17 alpha, 20 alpha, 21-tetrol-3-one from urine of man.


Vitamin B12 and protein biosynthesis.

Vitamin B12 and protein biosynthesis.


A new reagent for the detection of hydroxyproline on paper chromatograms.


Factors required for amino acid incorporation by disrupted ribonucleoprotein particles.


Arsenite inhibition; a property common to aldehyde dehydrogenases.


C-and N-terminal amino acids of human serum lipoproteins.


Preliminary attempt to correlate paper-electrophoretic migration of hemoglobins with phylogeny in Amphibia and Reptilia.


The flavonoid constituents of barley (Horedum vulgare). I. Saponarin.


Survival of Pasteurella tularensis in gelatin-saline after cooling and warming at subzero temperatures.


The occurrence of the pentose phosphate pathway in Ascaris lumbricoides.


The catabolism of cytidine 3'-phosphate by rat liver preparations.


Specific methods for the microdetermination of pyridine nucleotides and pyridine nucleotide enzymes.


Vitamin interrelationships in Lactobacillus leichmannii 313.


Excretion of steroids by the newborn infant.


Isolation and properties of cytochrome b5 from pig liver.


Preparation and properties of a microsomal DPNH-cytochrome c reductase.


Some factors influencing the excretory pattern of cesium-134 in rats.


A simple relationship for a calculation of the on velocity constant in enzyme reactions.


Mechanism of the reduction of triphenyltetrazolium chloride by succinoxidase.


Optical rotation and viscosity of native and denatured proteins. IX. Some plasma proteins at various pH.


Electric birefringence studies of irradiated deoxyribonucleic acid.


Surface active agents and cellular metabolism. I. The effect of cationic detergents on the production of acid and of carbon dioxide by baker's yeast.


Peptic hydrolysis of ovalbumin modified by acetylation.


Physiological basis for rhamnose utilization by a mutant of Pasteurella pestis. II. A single mutational event leading to the production of two enzymes.


Studies on the proteolytic enzyme system of the pancreas.


The binding of ions to the muscle proteins; a theory for K+ and Na+ binding based on a hydrogen-bonded and chelated model.


Serum protein-bound galactose and mannose as studied with C14-labeled glucose and fructose.


Electrophoresis of beta-lactoglobulin in the presence of calcium chloride.


The formation of hydrogen peroxide in the reaction of oxyhemoglobin with methemoglobin-forming agents.


Composition of the photoactive subcellular particles from Chromatium.


Studies on the enzymatic degradation of the cholesterol side chain. II. Requirements of the mitochondrial system.


Effect of 5-fluorouracil on the incorporation of precursors into nucleic acid pyrimidines.


Bound biotin in oxaloacetic carboxylase preparations.


Metabolic activity of protein amide groups.


On growth and development. II. Physiological considerations.


Interstitial mononuclear pneumonia; a cause of sudden death in Gurkha infants in the Far East.


On growth and development. I. Anatomical considerations.


Adrenocortical hyperplasia in childhood.


Aetiology of cholelithiasis in childhood.


The electron microscopy of endocardial fibroelastosis.


Hypophosphatasia.

Hypophosphatasia.


Protein-bound iodine levels in mothers and infants at birth.


Phenylketonuria with normal intelligence and Gowers' muscular dystrophy.


Mongolism in both of twins of opposite sex.


Peripheral vasomotor function in cretinism.


Cyanotic attacks in newborn infants.

Cyanotic attacks in newborn infants.


Night waking in early infancy. I.

Night waking in early infancy. I.


A preliminary report on the pathology of the pituitary gland in children with malnutrition.


Pulmonary function studies in normal boys.


Accidental digoxin poisoning in a child of 2 years.


Portal hypertension in fibrocystic disease of the pancreas.


Effect of trypsin on wound healing.

Effect of trypsin on wound healing.


The metabolism of methoxychlor (1,1,1 trichloro 2,2-bis (p-methoxyphenyl)ethane). I. The role of the liver and biliary excretion in the rat.


Blood pressure reversal by 1-norepinephrine and 1-epinephrine in rats adrenergically blocked and treated with ACTH.


Studies on the mechanism of action of a new hypoglycemizing compound N1-sulfanylil-N2-n-butylcarbamide.


Pharmacological actions on the carotid sinus baroreceptors in arterial hypertension.


10(2-Dimethylamino-1-propyl)-phenothiazine in experimental histamine shock.


Cutaneous vasomotor responses to sympathomimetic amines and adrenergic blockade.


Essential unsaturated fatty acids as vehicles for androgen administration.


Stimulus intensity, maximal electroshock seizures, and potency of anticonvulsants in rats.


The salivary secretion in man under the influence of intravenously infused acetyl-beta-methylcholine iodide.


Experimental studies with chlorpromazine; effect on cerebrospinal fluid pressure, blood pressure, respiration and pial vessel diameter in the cat.


A rapid bioassay for the estimation of epinephrine in peripheral blood.


Pharmacological action of rauwolscine. I. Adrenergic blocking activity.


Disposition of biosynthetically labeled C-14 podophyllotoxin in normal and tumor-bearing animals.


Central depressant drugs in neurotropic virus diseases.


The hemostatic, laxative and toxic effects of alginic acid preparations.


Potentiation of several hypnotic and anesthetic agents by colchicine.


The effect of testosterone on the carbohydrate metabolism in normal subjects.


Factors determining the intrapulmonary distribution of intravenously injected emboli in the dog.


Anticholinergic activity of the ortho-carboxybenzeneseleninic acid.


Eosinopenic activity of synthetic adrenal corticoids in mice.


In vitro synthesis of p-aminohippurate in the dog, rat, and rabbit as affected by sodium salicylate.


The action of bacterial demolition products in the electrophoretic immunitary picture of serum proteids.


Respiratory functions in man following intravenous administration of morphine, N-allylnormorphine, and N-allylnormorphine after morphine.


Effect of reserpine free extract of Rauwolfia serpentina on the action of ACTH and hydrocortisone in man.


Factors influencing pentobarbital sleeping time in mice.


Metabolic deëathylation of 5,5-dimethyl-3-ethyl-2,4 oxazolidinedione (dimedion).


Interaction of cholinesterase inhibitors with morphine and levallorphan.


A graphical method for studying the joint action of three substances.


A method of estimating drug effects on central excitability of the Siamese fighting fish.


An investigation of oxyethylstarch as a new plasma volume expander in animals.


An effect of drugs derived from 4-hydroxycoumarins not depending on hypoprothrombinaemia.


[Advantages and disadvantages of repeated punctures in the treatment of cirrhotic ascites].


Hypo- and hyperthyroidism in mongolism.

Hypo- and hyperthyroidism in mongolism.


Some possible etiological factors in the recurrent vomiting of children.


The treatment of mental deficiency and encephalopathies in childhood by means of fresh tissue and siccacell.


Growth problems in children.

Growth problems in children.


The latest developments in dry cell therapy (siccacell).


Gradients of functional ability of importance in rehabilitation of patients with progressive muscular and neuromuscular diseases.


Hemorrhage of syphilitic origin in the newborn.


Measurements of peripheral blood flow under conditions of physiologic stress.


Muscular strength-endurance relationships.


Flexibility characteristics of three specialized skill groups of champion athletes.


Trends in medical education.

Trends in medical education.


[Chlorpromazine metabolism studied by chromatographic method].


[Cholinesterase activity in blood & uterine muscle in fibromatosis].


[Immediate and remote results of endocavitary aspiration according to Monaldi's technic].


[Endocavitary aspiration in pulmonary abscess].


[Endocavitary aspiration in the treatment of pulmonary abscess].


Wandering kidney.

Wandering kidney.


Incarcerated diaphragmatic hernia.

Incarcerated diaphragmatic hernia.


Vesico-intestinal fistula complicating regional enteritis.


Malignant haemangiomata.

Malignant haemangiomata.


A case of retrocaval ureter in a two-year-old girl.


Bilateral testicular seminoma associated with bilateral cryptorchism.


Hypothermia, its principles and biochemical disturbances.


Results obtained with oxytetracycline in the treatment of chromic infections of the urinary tract and the bile passages.


Notes on the history of clinical thermometry.


The treatment of mumps and its complications in the adult male.


Diagnosis and management of common gynecological problems.


Bilateral traumatic pseudocystic pulmonary hematomas.


On the presence of an antineoplastic principle in normal tissues.


The dynamics of the intra-ventricular block. I. Experimental left block.


Side actions of drugs used in therapeutics.


Failure to inactivate urease with near-infrared radiation.


The determination of vitamin B12-activity in the organs and excreta of sheep. 4. The separation of vitamin B12-active factors from rumen contents by paper ionophoresis.


The metabolism of lower fatty acids in diabetic sheep.


Ectromelia virus multiplication in regenerating mouse liver.


Cardiac metabolism. IV. Seasonal variation; seasonal variation in metabolism and drug sensitivity of the isolated toad heart (Bufo marinus).


Studies on intermediary iron metabolism. X. The influence of age and sex on the storage of supplemental dietary iron in the rat.


The application of diffuse reflection spectrophotometry to chemical analysis.


A comparison of methods for the isolation of melanocyte stimulating hormone from blood.


A metabolic aspect of renal hypertension.


Studies on the intracellular distribution of protein-bound amino-azo dyes in rat liver.


The invasion of the chick embryo by ectromelia virus after inoculation on the chorioallantoic membrane.


Experimental vectors of the first larval stage of Dibothriocephalus latus (Cestoda) in Australia.


Landmarks and legends of the anal canal.


The effect of continuous administration of cortisone and its withdrawal on bone.


Hydatid cysts in paraspinal muscle compartments; their tendency to invade the spinal canal.


Nerves in tumours.

Nerves in tumours.


Spontaneous rupture of the spleen in infectious mononucleosis.


Pilonidal sinus of the mons veneris.

Pilonidal sinus of the mons veneris.


Localized peritoneal hyperplasias with special reference to subperitoneal cysts.


The English translations of Harvey's works.


Cationic extracting agents for rhodopsin and their mode of action.


Studies in detoxication. LXX. Metabolism of hydrazides and hydroxamic acids derived from salicylic acid.


The hydrolysis of indoxyl esters by esterases of human blood.


Observations on the presence of plasma proteins in skin and tendon.


The heterogeneity of bovine beta-lactoglobulin.


Determination of free and combined inositol in the un-germinated bean seed and the young plant.


Kinetics of the reaction between trypsin and the pancreatic trypsin inhibitor.


Protease inhibitors from Ascaris lumbricoides.


The activity and specificity of inducers of penicillinase production in Bacillus cereus, strain NRRL 569.


The role of magnesium in adrenal insufficiency.


Chromatography of guinea-pig native insulin.


Studies on phospholipids. I. The determination of amino nitrogen in unhydrolysed phospholipids.


Studies on phospholipids. II. 2:4-Dinitrophenyl-kephalins.


The heats of combustion of glycerol 1-phosphate, glycerol 2-phosphate and glucose 1-phosphate.


Some observations on the measurement of binding of cyanocobalamin by intrinsic factor preparations.


Sucrose formation by Taka-diastase; action of the enzyme of methyl beta-fructofuranoside and raffinose.


Mathematical derivation of the yields of the products of hydrolysis of the hexapeptide Ser.Gly.Ala.Gly.Ala.Gly.


The amino acid sequence in a fraction of the fibroin of Bombyx mori.


The effect of growth hormone upon cell division and nucleic acid synthesis in the regenerating liver of the rat.


L-cystathionine in the urine of pyridoxine-deficient rats.


Renal clearance of 17-oxo steroid conjugates found in human peripheral plasma.


A new method for the isolation of deoxyribonucleic acids; evidence on the nature of bonds between deoxyribonucleic acid and protein.


Studies with 15N-labelled nitrogen mustards; the combination of di-2-(chloroethyl)methylamine with proteins.


The determination of the structure of unsaturated fatty acids on a micro scale with the gas-liquid chromatogram.


Pyridoxamine phosphate transaminase.

Pyridoxamine phosphate transaminase.


A comparison of sodium salicylate and 2:4-dinitrophenol as metabolic stimulants in vitro.


Studies on sulphatases. XVIII. Preparation of chondroitinase-free chondrosulphatase from extracts of Proteus vulgaris.


Further studies on the reaction of disulphides with silver nitrate.


The indentification of natural and induced bacterial antibody with the serum components in sheep.


The formation of complexes between haemoglobins and plasma proteins in a variety of animals.


The degradation of glycine by Pseudomonas aeruginosa.


The isolation of D-glycero-D-galactoheptose and other sugar components from the specific polysaccharide of Chromobacterium violaceum (BN).


Uridine diphosphoglucose dehydrogenase of pea seedlings.


Some properties of a zinc-dependent hexokinase from Neurospora crassa.


The absorption of 131I-labelled homologous and heterologous serum proteins fed orally to young rats.


The survival of globulins absorbed from the gut in suckling rats.


Studies on the portal blood of sheep. I. Absorption of ammonia from the rumen of the sheep.


Studies on the portal blood of sheep. II. Absorption of volatile fatty acids from the rumen of the sheep.


The fractionation of bovine delta-globulin by partition chromatography.


An improved method for the microdetermination of arginine by use of 8-hydroxyquinoline.


Colorimetric determination of tyrosine.

Colorimetric determination of tyrosine.


The metabolism of the trichloronitrobenzenes in the rabbit.


Labelling of phospholipid phosphorus in rat-brain dispersions.


Labelling of phospholipid phosphorus in rat-brain mitochondria.


Incorporation of 32P-labelled intermediates into the phospholipids of cell-free preparations of rat brain.


The influence of intravenous glucose on blood-insulin activity in the rat.


Some hormonal influences on the glucose uptake of normal rat diaphragm in vitro.


Metabolism and metabolic response to electrical pulses in white matter from the central nervous system.


The composition of isolated cerebral tissue; purines.


The incorporation of phosphate into cerebral phosphoportein promoted by electrical impulses.


The isolation of 16alpha-hydroxydehydroepiandrosterone (3 beta:16 alpha-dihydroxyandrost-5-en-17-one) from the urine of normal men.


The role of serum albumin as a precursor of the soluble tissue proteins and the serum globulins of the rat bearing liver tumours.


The isolation and properties of a fragment of bovine-serum albumin which retains the ability to combine with rabbit antiserum.


Polynucleotides; partial purification and properties of a polynucleotide phosphorylase from Micrococcus lysodeikticus.


The sulphatase of ox liver. VI. Steroid sulphatase.


Incorporation of radiophosphorus into nucleic acids of vitamin B12-deficient rat tissues.


Histones from normal and malignant cells.


Chromatography of histones.

Chromatography of histones.


A consideration of myeloid-erythroid balance in man.


Melanin and its precursors. VIII. The oxidation of methylated 5:6-dihydroxyindoles.


Leukemia or lymphoma and coexistent primary malignant lesions: a review of the literature and a study of 120 cases.


Serum vitamin B12 in leukemias and malignant lymphomas.


The role of the mature neutrophil in bacterial infections in acute leukemia.


In vitro incorporation of C14-DL-leucine into normal and leukemic white cells.


The osmotic resistance of leukocytes in peripheral blood and splenic circulation of the rabbit.


The nature of the hemorrhagic disorder accompanying hemolytic transfusion reactions in man.


A metabolic study of a patient with idiopathic cyclical thrombocytopenic purpura.


[Partial limited alopecia of the scalp].


[Potentiation of the anti-inflammatory effect of cortisone and prednisone with 11-dehydrocorticosterone in rats. II].


[Muscular and hepatic cholesterol in rats subjected to endocrine gland excision].


[Spectral properties of bile pigments extracted from urine of jaundiced subjects].


[Action potentials of muscles in arterial patients subjected to function tests].


[Solitary extracranial neurilemmomas of the head; anatomy & clinical manifestations in 16 cases].


The use of a homatropinium derivative to produce controlled hypotension.


The influence of mecamylamine on the action of certain other ganglionic blocking agents.


Electrocardiographic studies during endotracheal intubation and inflation of the cuff.


Anaesthesia for prostatectomy.

Anaesthesia for prostatectomy.


A suction catheter holder.

A suction catheter holder.


Expendable plastic tubes for use with catheter holder.


Provision of water for suction.

Provision of water for suction.


Agricultural science and improved human nutrition.


A two-stage theory of carcinogenesis in relation to the age distribution of human cancer.


Tonsillar involvement in sarcoma of the alimentary lymphoid tissue.


Some observations on the spread of lung cancer in the body.


The production of lung tumours in rats by 3:4 benzpyrene methylcholanthrene and the condensate from cigarette smoke.


Polycyclic hydrocarbons in cigar smoke.

Polycyclic hydrocarbons in cigar smoke.


The effect of the hair growth cycle on experimental skin carcinogenesis in the rabbit.


Epidermal carcinogenesis in the mouse by intraperitoneally administered urethane followed by repeated applications of croton oil.


Cancer of the urinary bladder induced in mice with metabolites of aromatic amines and tryptophan.


The effect of a single injection of high dose of 90Sr (500-1000 muc./kg. in rabbits.


Mammary tumours induced with ovarian hormones substituted after ovariectomy in RIIIf virgin female mice.


Sensitivity of the weanling rat thyroid to radiation.


The distribution of radioactivity in tissues of the rat following the administration of a nitrogen mustard derivative; p-di-(2-chloroethyl) amino-DL-phenyl[beta-14C] alanine.


Observations on the Rous virus; fine structure and relation to cytoplasmic vacuoles.


The cultivation in vitro of mouse ascites tumour cells; the relation between density of cell population, viability and mitosis in pure cultures.


The cultivation in vitro of mouse ascites tumour cells; the morphology and behaviour of the tumour cells in pure cultures.


The antigenic composition of mouse ascites tumour cells using in vitro and gel-diffusion techniques.


The effect of the degree of homogenization on the catalase activity of liver homogenates.


Biogenesis of 5-hydroxytryptophan.

Biogenesis of 5-hydroxytryptophan.


Ocular signs of leukaemia.

Ocular signs of leukaemia.


The use of cortisone in alopecia areata and totalis.


The radiological investigation of diseases of the ear, nose and throat.


Canicola fever.

Canicola fever.


Dangers of treatment in bed for the aged.


Student health.

Student health.


Mycosis fungoides.

Mycosis fungoides.


Malaria in England.

Malaria in England.


Management of alcoholism.

Management of alcoholism.


Progress report. I. Anaesthesia.

Progress report. I. Anaesthesia.


Progress report. II. Ophthalmology.

Progress report. II. Ophthalmology.


Demonstrations in pathology; bones. II.

Demonstrations in pathology; bones. II.


The requirements and cost of an industrial medical service.


Histological lesions of muscle in dermatomyositis; differentiation from related musculo-cutaneous syndromes.


Tinea cruris in women; a report of three cases.


Subacute hypodermic nodules of vascular origin.


Keratosis follicularis serpiginosa (Lutz); elastoma intrapapillare perforans verruciforme (Miescher).


Traumatic marginal alopecia; a special type: alopecia groenlandica.


Liver biopsy in eczema and other dermatoses.


Angioma serpiginosum.

Angioma serpiginosum.


Studies on the mechanism of shock, the effect of limb ischaemia on the phosphates of muscle.


Further evidence of the antileptospiral effect of milk: electron microscopic studies.


The Danysz effect: an investigation of the reaction between an enzyme and its antibody.


The heterogeneity of infective virus particles within a single influenza virus strain.


Immune-adherence of bacteriophage T2.

Immune-adherence of bacteriophage T2.


Generalized common and hypertrophic warts.


Actions of adenovirus types 5 and 7 in cultures of rabbit kidney tissue.


Intractable pustular eruptions of the hands and feet; a review of 70 patients.


Effect of homologous bone marrow injections in x-irradiated rabbits.


The effect of local application of hydrocortisone in dermatitis herpetiformis.


The influence of corticotrophin and certain corticosteroids on populations of Mycobacterium tuberculosis in tissues of mice.


The influence of corticotrophin and cortisone with antituberculous drugs on population of Mycobacterium tuberculosis in tissues of mice.


The effects of high blood cholesterol on the pulmonary arterial changes produced in rabbits by the injection of blood clot.


Enzyme-like globulins from serum reproducing the vascular phenomena of inflammation. III. Further observations on the permeability factor and its inhibitor in guinea-pig serum.


The permeability-increasing factor in diluted human plasma.


The route of immunization in transplantation immunity.


Mineral requirements for growth of Staphylococcus pyogenes; effect of sodium ions.


Treatment of murine leukaemia with x-rays and homologous bone marrow. II.


The site of absorption and tissue distribution of orally administered 56Co-labelled vitamin B12 in the rat.


Electrophoretic studies on sera containing high-titre cold haemagglutinins: identification of the antibody as the cause of an abnormal gamma 1 peak.


Eluting red-cell antibodies: a method and its application.


The fibrinolytic activity of human tissues.


Platelet 5-hydroxytryptamine (HT) in disorders of the blood.


Reactivity of stored plasma to thrombin, with reference to the fibrinogen conversion accelerator and heparinoid activity.


Experimental haemolytic anaemia with particular reference to the corpuscular haemoglobin concentrations of the erythrocytes.


Determination of the sites of red-cell destruction using 51Cr-labelled cells.


Papain, ficin and bromelain in the detection of incomplete Rhesus antibodies.


The ailment.

The ailment.


An experimental approach to the psychopathology of childhood: encopresis.


The relevance of genetic psychology for the psychopathology of schizophrenia.


Reminiscence and work decrement in catatonic and paranoid schizophrenics.


Joint-interview technique: an experiment in group therapy.


Environmental influence on intellectual function as measured by intelligence tests.


Protein metabolism in chronic severe malnutrition (kwashiorkor), absorption and retention of nitrogen from a typical poor Mexican diet.


Iron-deficiency anaemia in calves.

Iron-deficiency anaemia in calves.


The heat increment of steam-volatile fatty acids in fasting sheep.


Diurnal variations in the composition of the faeces of pigs on diets containing chromium oxide.


Volatile fatty acids and lactic acid in the rumen of dairy cows receiving a variety of diets.


The role of fat in the diet of rats. 11. Influence of a small amount of ethyl linoleate on degeneration of spermatogenic tissue caused by hydrogenated arachis oil as the sole dietary fat.


Effect of level of protein intake and of age of rat on the biological value of proteins.


Vitamin B12 and methyl-group synthesis.

Vitamin B12 and methyl-group synthesis.


Methionine sulphoximine and the growth of the wheat embryo.


The effect of hexoestrol implantation on carcass composition and efficiency of food utilization in fattening lambs.


Effect of diencephalic stimulation upon intra-ocular pressure.


Fuchs's epithelial dystrophy of the cornea.


A pedigree of anophthalmos.

A pedigree of anophthalmos.


Acute ocular onchocerciasis and its treatment.


A new medium for the storage of donor eyes for corneal grafts.


Retroposition of the conjunctiva; a new approach to trachomatous entropion.


Chlorpromazine in ocular surgery.

Chlorpromazine in ocular surgery.


Mooren's ulcer treated by diathermy coagulation.


Intra-ocular fragment of aluminium alloy tolerated for 12 years.


The distribution of acetylcholine in the Malayan jack-fruit plant, Artocarpus integra. The distribution of acetylcholine in the seeds and leaves of the Malayan Jack-fruit plant, Artocarpus integra, has been studied with the view to obtaining evidence for the site of its formation. The terminal growing leaves on the side branches had a very high concentration of acetylcholine (770 mug./g.), while the acetylcholine content of the other leaves on the same branch progressively decreased with age. The total amount of acetylcholine stored in the terminal growing leaves was only 42 mug., but in the second leaves which had grown nearly to their full size it was 540 mug. From the third leaves, the amount of acetylcholine stored gradually decreased. The midribs and the secondary veins of the leaves when combined had a higher concentration of acetylcholine than had the blades. The acetylcholine concentration of the pith of the stem was 4.2 times higher than that of the cortex-phloem layer while that of the xylem layer was the lowest; in the root the pith had a value only one-seventh of the cortex. The younger part of the pith and the cortex-phloem layers of the stem contained more acetylcholine than the older parts. These findings support the view that the acetylcholine is synthesized in the growing leaves. An unusual lenticel-like structure in the cortex layer of the root contained more acetylcholine than the surrounding tissue.


The effect of dinitrophenol, hypoxaemia and ischaemia on the phosphorus compounds of the dog heart. The results reported in this paper indicate that dinitrophenol acts directly on the isolated heart, increasing its metabolic rate. It also produces heart failure associated with a low phosphocreatine content of the muscle but with no change in adenosine triphosphate, which may or may not be due to a relative hypoxia of the cardiac tissue. Experimental arterial hypoxaemia, if severe, produces a similar picture of heart failure with a decrease in phosphocreatine and no change in adenosine triphosphate. Ligation of the coronary arteries results in disappearance of the major part of the phosphocreatine within a few minutes regardless of whether or not ventricular fibrillation ensues; the adenosine triphosphate remains unchanged.


The mechanism of dinitrophenol heart failure. Hypoxaemia, resulting from increased tissue metabolism, is an important factor in dinitrophenol failure in the conventional heart-lung preparation. Improved oxygenation of the blood by a technique described in this paper prolongs the life of dinitrophenol-treated hearts. Dinitrophenol acts very rapidly; oxygen consumption and coronary flow increase in a few minutes and the increase is proportional to the dose. The increase in oxygen consumption diminishes with time. Dinitrophenol decreases the phosphocreatine content of the heart, even when there is no failure or hypoxia. There is no evidence that dinitrophenol failure can be due to a decrease of phosphocreatine or adenosine triphosphate content of the heart, although this is to be expected in view of the observed "uncoupling" action of dinitrophenol.


The effect of diuretics on the water excretion of protein deficient rats. Adult rats kept for eleven weeks on a diet deficient in protein lost weight and some developed scrotal oedema. The retention of bromsulphthalein was increased, but the thymol turbidity test was unaffected; the apparent plasma volume was increased.Water diuresis in the protein deficient animals was impaired. There was no apparent delay in the mean rate of water absorption from the whole gastro-intestinal tract although a delayed absorption of water from the intestine was found in some animals. The concentrations of total plasma proteins and plasma albumin were low as compared with normal animals, but the plasma sodium levels were within normal limits. The inulin clearance (glomerular filtration rate) of the animals on the protein-deficient diet was significantly lower than that of the controls.In normal rats, aminophylline and acetazolamide were diuretic. Caffeine and sodium benzoate did not increase the urine output and mersalyl was antidiuretic. In the protein deficient rats, cortisone acetate increased the water diuresis. Caffeine and sodium benzoate, aminophylline and acetazolamide did not significantly increase this response, mersalyl had an antidiuretic effect. Cortisone acetate increased the food and water intake of the protein deficient rats; it also increased the glomerular filtration rate.


The metabolism of exogenous and endogenous antidiuretic hormone in the kidney and liver in vivo. Negligible antidiuretic activity (less than 0.17 mU./g.) was found in extracts of the kidneys either of unanaesthetized adult rats in normal water balance or of rats in whose blood a rise of the level of endogenous antidiuretic hormone had been induced by ether anaesthesia. Extracts of the livers of unanaesthetized rats had negligible antidiuretic activity (less than 0.06 mU./g.), but liver extracts from rats anaesthetized with ether showed antidiuretic effects equivalent to 0.74+/-0.24 mU. Pitressin/g. liver. When Pitressin was injected intravenously into unanaesthetized rats, small amounts of antidiuretic activity were occasionally found in the livers and the kidneys of animals killed up to 3 min. after the injection but none in animals killed later. Some 3% of the antidiuretic activity of an injected dose of Pitressin was found in the urine and the "dead space" of the kidneys in rats decapitated 3 min. after the intravenous injection. When Pitressin was added to rat kidney homogenate and the mixture was incubated at 38 degrees , only 0.75% of the initial antidiuretic activity was recovered after 30 min. and less than 0.40% after 60 min. Experiments with "glomerular" and "tubular" fractions of rat kidney indicated that the inactivation was essentially due to tubular tissue. It is suggested that, in the rat, the kidneys and perhaps the liver are not only sites of clearance of the antidiuretic hormone but also sites of irreversible inactivation.


The effect of inhalation of 30% carbon dioxide on the peripheral circulation of the human subject. Inhalation of 30% carbon dioxide for 1 to 2 min. caused a transient increase followed by a marked fall in blood flow through the normal forearm and calf. Since there was an associated large increase in arterial blood pressure, the fall in flow was due to intense vasoconstriction. It is likely that the vasoconstriction in the forearm occurred deep to the skin because the oxygen saturation of the superficial venous blood did not fall during the inhalation. Since there was a slight decrease in flow through the nerve-blocked forearm in spite of the increased blood pressure, it is unlikely that nervous vasoconstriction can completely account for the marked decrease in muscle flow.


The blocking action of choline 2:6-xylyl ether bromide on adrenergic nerves. Choline 2:6-xylyl ether bromide (TM 10), given systemically to cats in doses of 5 to 15 mg./kg., abolishes the effects of adrenergic nerve stimulation whilst leaving the reactions of the effector organs to adrenaline unimpaired. The effects of a single dose may take up to one hour to become fully established and last for more than twenty-four hours. Apart from transitory ganglionic blockade, cholinergic autonomic nerves are unaffected even by large doses of TM 10. Doses of TM 10 which produce effective blockade do not impair conduction along adrenergic nerve trunks; the drug must, therefore, act at, or close to, the nerve terminals. TM 10 prevents the output of noradrenaline from the spleen on stimulating the splenic nerves; but, in acute experiments, it does not influence the liberation of pressor amines from the stimulated suprarenals. Examination of some ethers related to TM 10 revealed no correlation between TM 10-like adrenergic blocking activity and local anaesthetic activity. The action of TM 10 on adrenergic nerves does not, therefore, seem to be accounted for by axonal block.


Effects of choline 2:6-xylyl ether bromide upon the suprarenal medulla of the rat. The administration of choline 2:6-xylyl ether bromide (TM 10) daily to rats for two weeks depletes the suprarenals of about one-half their normal content of adrenaline and noradrenaline. This depletion has been demonstrated histologically and by colorimetric and biological estimation of the amines present in extracts of the glands. Treatment with TM 10 causes similar histological signs of depletion in autografts of adrenal chromaffin tissue in the rat iris. Restoration of catechol amines in rat suprarenals, previously depleted by TM 10, occurs slowly and appears to be complete 14 days after withdrawing the drug. These results, considered in conjunction with the estimated rate of turnover of catechol amines in the rat suprarenal, lend support to the view that TM 10 may interfere with the biosynthesis of these amines.


Some actions of substituted choline phenyl ethers, particularly of choline 2:6-xylyl ether. Marked nicotine-like stimulant properties are possessed by choline phenyl ether and choline o-tolyl ether, and to a decreasing extent by choline 2:6-xylyl ether and choline 2:4:6-mesityl ether. The compounds all show neuromuscular blocking properties, which are of short duration and pass from mainly decamethonium-like to mainly curare-like as more methyl groups are added to the phenyl nucleus. This series of compounds also possesses muscarinic, weak anti-adrenaline and vasodilator properties, as well as long-lasting local anaesthetic effects in the two compounds tested by intradermal injection.


The action of substances analogous to diaminodiphenoxyalkanes against Schistosoma mansoni. The effects on activity against Schistosoma mansoni of further modifications of the diaminodiphenoxyalkanes are reported. Replacement of the amino-group by any of a large number of other groups destroys activity. Activity is retained in the presence of certain substituted (hydroxyalkyl, carboxyalkyl) amino-groups and in some of their aldehyde-bisulphite derivatives. Many variations of the central chain lead to compounds of reduced activity, the outstanding exceptions being a number of but-2-ene derivatives, which retain full activity.


The enzymatic hydrolysis of imidazoleacryloylcholine (murexine) and imidazolepropionylcholine (dihydromurexine) by various cholinesterases. Several choline esters, including the imidazoleacryloyl and imidazolepropionyl compounds, have been hydrolysed by cholinesterases from various sources. The imidazolepropionyl ester was metabolized by cholinesterases obtained from human plasma, ox spleen, ox serum, and guinea-pig liver, but not by rat liver or bovine red cell cholinesterase. It is suggested the imidazolepropionylcholine or a closely related ester might be the natural substrate for "non-specific" cholinesterase.


Two kinds of tryptamine receptor.

Two kinds of tryptamine receptor. There are two kinds of tryptamine receptor in the guinea-pig ileum, namely the M receptors which can be blocked with morphine and the D receptors which can be blocked with dibenzyline. Atropine, an atropine-like drug, cocaine, and methadone inhibit effects due to the M receptors, even after dibenzyline, but have no additional effect after morphine. Lysergic acid diethylamide, dihydroergotamine and 5-benzyloxygramine inhibit effects due to the D receptors, even after morphine, but have no additional effect after dibenzyline. The M receptors are probably in the nervous tissue and the D receptors are probably in the muscles.


The effect of carrier strontium on the absorption of oral doses of radioactive strontium in rats. Carrier strontium had relatively little effect on the retention of an oral dose of radioactive strontium by the rat when it was administered immediately after the radioactive dose. The proportion of the radioactive dose which was excreted in the urine, on the other hand, increased progressively with the carrier dose. There was a decreased uptake of radioactive strontium in rats fed on a special low strontium diet. The effects of dietary strontium are discussed. Evidence was found of a discrimination by the rat against strontium in favour of calcium which was accounted for, at least in part, by a preferential urinary excretion of strontium.


Oximes and atropine in sarin poisoning.

Oximes and atropine in sarin poisoning. Three oximes, monoisonitrosoacetone (MINA), pyridine-2-aldoxime methiodide (PAM) and diacetylmonoxime (DAM), have been examined in combination with atropine as antidotes in sarin poisoning. When treatment was administered 15 min. before sarin, atropine enhanced the protective effect of MINA and DAM 2 to 3 times and of PAM 9 to 10 times in mice and rats. In mice, rats, and guinea-pigs, atropine increased by no more than 2 times the protective effect of all three oximes when given 30 sec. after sarin. Atropine given to monkeys 1 min. after sarin raised the LD50 approximately 3 times. When given in conjunction with MINA or DAM, the LD50 of sarin was raised 7 to 14 times.


A sensitive method for the assay of 5-hydroxytryptamine. The movements of a strip of fundus from a rat stomach, suspended in a 5 ml. bath at 37 degrees , are recorded by a spring-loaded lever. The muscle is stretched for 15 to 30 sec. between contractions. 1 ng. 5-Hydroxytryptamine (5-HT), 10 ng. acetylcholine or 2 to 10 mug. of histamine all produce contractions, giving tracings about 4 cm. high. In the presence of hyoscine (10(-7)) low concentrations of 5-HT can be assayed directly from mixtures of the three substances. Sympathomimetic amines interfere with the assay, but this can be overcome. The preparation is robust, potentially suitable for use with an automatic assay apparatus and 10 to 100 times more sensitive than the rat uterus.


The action of hypoglycaemic sulphonylureas on carbohydrate metabolism in the fasted rat. Tolbutamide and carbutamide given orally to fasted rats cause a rise in the liver glycogen content 1(1/2) to 3(1/2) hr. after administration of the drugs. Glycogen accumulates preferentially in the right lobe. Subcutaneously injected tolbutamide has the same effect. Both sulphonylureas cause inhibition of glucose-6-phosphatase activity of rat liver homogenates in vitro, but at drug concentrations comparable with those found in plasma of treated patients the degree of inhibition is less than 10%. Livers from treated rats show normal glucose-6-phosphatase activity. The glucose uptake of the isolated rat diaphragm is unaffected by the sulphonylureas added in vitro. Diaphragms from treated rats show normal glucose uptake in the presence or absence of insulin. The inferences to be drawn from these results are discussed in the light of previous work. It is concluded that the sulphonylureas exert hypoglycaemic action by inhibiting glycogenolysis and it is suggested that they might do so by inhibiting release of glucagon from the pancreas.


Lipid biosynthesis and chemically induced paralysis in the chicken. Dyflos (diisopropylphosphorofluoridate, DFP) retards the synthesis of lipid in the sciatic nerve of the chicken in vivo. A similar inhibition occurs in vitro, but only at relatively high concentrations (10(-3)M) of the drug. The major portion of the (14)C supplied as acetate, and incorporated into lipid, is found with the fatty acids. Attempts to separate the lipids involved by paper chromatography were unsuccessful.


The preservation of substance P by lysergic acid diethylamide. Lysergic acid diethylamide (LSD) potentiated the response of guinea-pig ileum to substance P but not to histamine. It also inhibited the disappearance of substance P when incubated with guinea-pig brain extract but not when incubated with chymotrypsin. Eserine, morphine, mescaline, chlorpromazine, ergometrine, strychnine and 2 bromo-LSD did not have this effect. Oxytocin was not destroyed by brain extract. The inhibition of the destruction of substance P by LSD could be antagonized by 2 bromo-LSD. This effect of LSD may have some relation to its pharmacological actions.