Some transmission characteristics of the tubule-inducing influence on mouse metanephrogenic mesenchyme.


The electron distribution in some high energy phosphates and the transfer of energy from catabolism to anabolism.


A polarizing and electron microscope study of plasma cells.


Technical improvements in specimen preparation for electron microscopy.


The in vitro incorporation of C14-leucine into the proteins of tumor microsomes and a note on the properties of isolated tumor mitochondria.


Effects of androgens on the cytology of x-irradiated seminal vesicles.


Comparative mass determinations of isolated liver cell nuclei by schlieren and interference microscopy.


Catabolism of glycine-C14 by washed bovine spermatozoa.


Dye uptake and survival studies in x-irradiated yeast cells.


The arrest of mitosis and stomatogenesis during temperature-induction of synchronous division in Tetrahymena pyriformis, mating type 1, variety 1.


Non-protein sulfhydryl compounds in the division of eggs of Strongylocentrotus purpuratus.


Evidence for the cytoplasmic formation of hemoglobin.


Protective effect of 2-mercaptoethylguanidine on bone marrow cells x-irradiated in vitro.


DPNH-oxidase activity in fragments of rat liver mitochondria.


A project for the development of quantitative methods for the endocellular range.


A coordinated set of instruments for optical quantitative high resolution cytochemistry.


Quantitative behaviour of cytoplasmic RNA in rat Purkinje cells following prolonged physiological stimulation.


Computers for microphotometric data analysis.


Recording microspectroscopy for the study of intracellular reactions.


The ultra-violet absorptivities of DNA and other substances in cells.


A method for investigating the stoichiometry of Feulgen stain.


Interferometry and refractometry of cells in tissue culture.


Attempts at measurement of lipid, nucleic acid and protein content of cell nuclei by microscope-interferometry.


An interference microscope for rapid measurements of biological objects.


Some considerations concerning the merits of interference microscopes.


Scanning interference microphotometry.

Scanning interference microphotometry.


Quantitative historadiography: procedures and application.


Evaluation of microradiograms for dry weight determination.


Quantitation and automation in contact microradiography.


A discussion of recent advance towards quantitative autoradiography.


A new change-over optical system and a direct recording microscope for quantitative autoradiography.


Quantitative aspects of autoradiography.


Some extensions of the Linderstrøom-Lang and Holter quantitative histochemical method for the localization of enzymes and other constituents in cells and tissues.


Determinations of C14 compounds in nerve tissue constituents.


Some critical comment in the chemical estimation of nucleic acids in tissues.


Necessary conditions for the separation of compounds at quantitative cell analyses.


Microbiological determination of DNA; the growth of Thermobacterium acidophilum on a chemically defined medium.


An attempt of using biochemical methods for cytochemical problems; the desoxyribonucleoprotein of spermatogenetic cells of bull testis.


Antiparasitic action of dietary cod liver oil upon Plasmodium berghei and its reversal by vitamin E.


Occurrenc and distribution of trehalose and glycogen in the eggs and tissues of Ascaris lumbricoides.


Amino acids in larval and adult tapeworms (Hymenolepis diminuta) and in the tissues of their rat and beetle hosts.


Studies on the metabolism of Echinococcus granulosus. II. Some observations on the carbohydrate metabolism of hydatid cyst scolices.


Comparative experiments with a Florida strain of Litomosoides carinii in Eastern and Texas cotton rats.


The concept of vector efficiency in experimental studies of plague.


The host specificity of monogenetic trematodes.


On some neuro-oto-ophthalmological manifestations of systemic lupus erythematosus and polyarteritis nodosa.


A new ophthalmic solution: preliminary report.


Significance of hypometabolism in otolaryngology: further studies.


The ocular history of James Joyce.

The ocular history of James Joyce.


Eustachian tube biopsy cannula.

Eustachian tube biopsy cannula.


Principles of block dissection of the neck.


Glaucoma briefs.

Glaucoma briefs.


The A and V syndromes.

The A and V syndromes.


Plastic surgery: esthetic surgery in the aged & aging.


Postoperative vision in retinal detachment surgery.


Healing of nasal fractures; a roentgen evaluation.


Nasopharyngeal irradiation; a review and critical analysis.


Role of the dermatologist in the management of external otitis.


[Effect of adenosinetriphosphoric acid on water-electrolyte metabolism in hypophysectomized rats].


Nestors in medical licensure service. I.


[Comparative characteristics of cardiac glycosides in experimental atherosclerosis].


The marks on the skin in some phacomatoses.


Diagnostic and therapeutic value of creative activities in the mental hospital.


A method of movement-analysis with psychiatric patients.


Pneumo-encephalography in cerebral infarction.


Two cases of absence of the septum pellucidum in the pneumoencephalogram.


In memoriam Prof. Dr. W. M. van der Scheer.


Afferent fibres to the intermediate and solitary tract nuclei, and their adjacency in man.


Psychopathology and symptomatology of the manic-depressive interjacent territory.


On leucodystrophy and leuco-encephalitis; the old conception; diffuse sclerosis; a study of the autopsy cases from an university clinic.


[Preliminary results with cytostatic E-39 in the treatment of malignant tumors].


Anatomic variances of the cystic and hepatic artery as seen during operations on the gallbladder.


Long-term anticoagulant therapy.

Long-term anticoagulant therapy.


Air and blood oxygen.

Air and blood oxygen.


Accessory lobes of the lung.

Accessory lobes of the lung.


Therapy of hypertensive states in pregnancy from the internist's standpoint.


The clinical management of osteoarthritis.


Regional enteritis.

Regional enteritis.


Admissions: a professional liability pitfall.


Erythropoietin.

Erythropoietin.


The treatment of lymphedema of the arms and legs.


The transmission of sound by the femur.

The transmission of sound by the femur.


Individual intravenous therapy for surgical patients.


The medicated nose.

The medicated nose.


Diabetic acidosis as a complication of therapy with tolbutamide.


Extracardiac disorders in heart failure.


The azygos vein.

The azygos vein.


Labor's new socialized medicine scheme.

Labor's new socialized medicine scheme.


Gastroenterology programs of the National Institute of Arthritis and Metabolic Diseases.


Observations on the course of benign gastric ulcer and factors affecting its prognosis.


Hypertrophic pyloric stenosis in adults.


Adrenocortical function in peptic ulcer disease.


Appendicitis in the aged.

Appendicitis in the aged.


Experimentally induced gastric ulceration and antisecretory property of sodium fluoride in the stomachs of young guinea pigs.


[Scientific works of Dr. Francisco Antonio Risquez in the National Academy of Medicine].


The simulation of jaundice by action of quinacrine (atabrine).


The effect of the antrum on histamine-produced ulcer in the experimental animal.


[Words spoken during the placing of a floral offering at the tomb of Dr. Francisco Antonio Risquez].


Cholelithiasis in sickle cell disease.

Cholelithiasis in sickle cell disease.


Frequency of recurrences in peptic ulcer.


Effect of cigarette smoking on dissolved gastric mucins and viscosity of gastric juice.


Obstructive jaundice; the problem of differential diagnosis in a patient with carcinoma of the major intrahepatic bile ducts.


A case of mucormycosis of the duodenum, liver and cecum.


Gastro-esophageal incompetence; its relationship to short-esophagus type of hiatal hernia in infancy.


Cyclic vomiting.

Cyclic vomiting.


The importance of maintaining a normal milieu intérieur.


[Continuous anesthetic block of the sciatic nerve in vascular disorders of the leg & foot].


Academic performance and personality adjustments of highly intelligent college students.


The use of the Vineland social maturity scale in the planning of an educational program for non-institutionalized low-grade mentally deficient children.


The structure and origin of the anal character.


Free expression of adolescents' interests.


The role of mass media and the effect of aggressive film content upon children's aggressive responses and identification choices.


Interest in persons as an aspect of sex difference in the early years.


Surgical treatment of internal carotid artery occlusion.


Nutritional and biochemical effects of 19-nortestosterone with lysine supplements in aging convalescents.


Serum cholesterol reduction with lecithin.


Clinical and pathologic correlation in pyelonephritis; statistical study of 977 patients.


Serum proteins in the aged; means and stability of mucoprotein levels and electrophoretic partitions.


Electroencephalographic alpha rate in adults as a function of age.


Nontraumatic cervical osteoarthritis in an aged patient.


Tumors of the hand.

Tumors of the hand.


The sociologic meaning of aging.

The sociologic meaning of aging.


Significance of levels of wellness in aging.


Gerontology: the university's opportunity and challenge.


[Etiopathogenetic considerations on two cases of Hyde's nodular prurigo].


[More discussion on the problems of tree planting in Leskovac].


Oogenesis in adult Drosophilia melanogaster. III. Radiation-induced ovarian tumors.


The ineffectiveness of meprobamate on growth and feed economy of white Leghorn cockerels.


Quantitative growth studies with chick myoblasts in glass substrate cultures.


The proportion of leucine and lysine to tryptophane in growing tissues.


Growth of the marsupial Trichosurus vulpecula and a comparison with some higher mammals.


The influence of light on the early growth of chinook salmon.


[Intrabronchial perforations of the lymph nodes & anatomicopathological lesions of the tracheobronchial lymph nodes in persons who died from fibrocavernous pulmonary tuberculosis].


Food allergy.

Food allergy.


Gastrointestinal Hodgkin's disease; a report of three cases.


Protruding ears.

Protruding ears.


Filling cavities remaining after unusual hernias.


A new needle for operating table cholangiography.


A retractor forceps.

A retractor forceps.


Carcinoid tumors of the gastrointestinal tract.


Papillary cystadenocarcinoma of the ovary.


Preanesthetic medication with pentobarbital sodium.


Cystic fibrosis of the pancreas.

Cystic fibrosis of the pancreas.


Recurrent ectopic pregnancy in the stump of a fallopian tube complicated by pyosalpinx; case report.


Atrophic rhinitis.

Atrophic rhinitis.


Meprobamate therapy; three years of observation on its use in adaptation and stress-induced conditions.


Venous pressure; changes in intrathoracic and intra-abdominal injuries.


Persistent occiput transverse position on the perineum; a method for rotation.


The interpretation of symptoms.

The interpretation of symptoms.


The first anticipations of the idea of circulation in ancient Jewish sources.


Sugar and cane sugar in Hebrew literature.


Psychosomatic problems in medical practice.


Management of colitis and diarrhea.

Management of colitis and diarrhea.


The anterior chest wall syndrome.

The anterior chest wall syndrome.


Harveian items in Hebrew medicine.

Harveian items in Hebrew medicine.


Changing concepts regarding splenectomy.


LOW SODIUM diet.

LOW SODIUM diet.


Ethnic differences in relation to morbidity in Israel.


Three decades.

Three decades.


The health of Israel.

The health of Israel.


Smallpox vaccination and pregnancy.

Smallpox vaccination and pregnancy.


Hypothalamus and hypophysis.

Hypothalamus and hypophysis.


Biochemical studies on the blood serum and cerebrospinal fluid of children suffering from tuberculous meningitis.


The annual hospital report.

The annual hospital report.


Small hospital's clinic: new profession.


What makes a good annual report.

What makes a good annual report.


Opinion survey questionnaire.

Opinion survey questionnaire.


The hospital of the future. III.

The hospital of the future. III.


The pharmacist as central service supervisor.


Salaries and supplementary benefits in private hospitals, 1956-1957. II.


Not by bread alone: the Blue Cross idea under the British National Health Service after 10 years.


SHOCK IN myocardial infarction.

SHOCK IN myocardial infarction.


Welding reduces equipment costs.

Welding reduces equipment costs.


Some legal aspects of hospital purchasing. III.


What the executive housekeeper expects from administration.


The hospital administrator and nursing accrediation.


The circulatory system of the giraffe.

The circulatory system of the giraffe.


How to recognize quality in stainless steel equipment.


Pharmacy service in smaller hospitals. II.


ACUTE myocarditis.

ACUTE myocarditis.


AA AND the hospital.

AA AND the hospital.


Don't overlook mental hospitals in disaster planning.


A place for old folks to live; fire safety in the nursing home. I. Ingredients for disaster.


Hospital-funeral directors relations.

Hospital-funeral directors relations.


City planning.

City planning.


Real fire training is real life insurance.


Fires and explosions.

Fires and explosions.


The engineer's responsibility for the security features of the hospital. I.


Control of surgical privileges. I.

Control of surgical privileges. I.


The framework of organization.

The framework of organization.


The challenge of the sterile suture scissors.


Automation in hospital records.

Automation in hospital records.


Package boiler is more efficient.

Package boiler is more efficient.


Housekeepers are educators.

Housekeepers are educators.


LARGER quantity purchases; a saving.

LARGER quantity purchases; a saving.


Flexibility in purchasing.

Flexibility in purchasing.


Why the shortage of x-ray technicians.

Why the shortage of x-ray technicians.


The American Public Health Association: 1872-1957.


Duplicating equipment.

Duplicating equipment.


HM salutes.

HM salutes.


Hospital liability for trustees and medical staff.


Some recent legal decisions indicating trends.


The engineer's responsibility for the safety features of the hospital. II.


A place for old folks to live; ingredients for disaster. II.


Historical and legal aspects of blood transfusions.


Hospital library service. I.

Hospital library service. I.


Hospital lien law.

Hospital lien law.


Control of surgical privileges. II.

Control of surgical privileges. II.


What's for tomorrow.

What's for tomorrow.


The administrator must be there; the administrator's need to represent himself at the site.


The elements of institutional sanitation personnel facilities.


USE RICE with your lenten meals.

USE RICE with your lenten meals.


Do your employees work for you.

Do your employees work for you.


The operations of a pharmacy and formulary committee.


X-RAY TECHNICIANS face unionization.

X-RAY TECHNICIANS face unionization.


The selection of incinerators for hospital use.


Is your public relations showing.

Is your public relations showing.


There are opportunities.

There are opportunities.


Smoothing the process of order giving.

Smoothing the process of order giving.


Hospital control the trend of prepackaging.


Hypnosis as anesthesia.

Hypnosis as anesthesia.


Hospital administration; which way.

Hospital administration; which way.


Juvenile visitors can be seen and heard; in place provided.


Lay assistants' contributions to Catholic hospitals.


Medical records.

Medical records.


Hospital nursing service organization.

Hospital nursing service organization.


Louisiana revisited; tornado strikes Boscoville and Prairie Laurent.


The forward look in nursing.

The forward look in nursing.


The status of radiologic technology in the modern hospital.


A MONUMENT to health.

A MONUMENT to health.


How and why we started an employee advisory committee.


The dietitian and professional responsibility.


Good records vindicate housekeeping methods.


FINANCIAL management course initiated at Regis College.


Listeria meningitis: a case report.

Listeria meningitis: a case report.


Stranded sisters open convalescent hospital.


A poison control center: a tool to end unnecessary tragedies.


The hospital sisters as a pr means: and an end.


Communication in nursing service.

Communication in nursing service.


Research, its meaning and characteristics.


The patient's personal property. I.

The patient's personal property. I.


Industry know-how helps hospitals.

Industry know-how helps hospitals.


The place of the lay assistant administrator in the catholic hospital.


THE PATRICIAN goes to Seneca.

THE PATRICIAN goes to Seneca.


Ultra sound: your silent servant.

Ultra sound: your silent servant.


Maintenance of electrical equipment for fire prevention.


Pharmacy personnel patterns.

Pharmacy personnel patterns.


Nutrition education for the medical intern.


Bedrails: up or down.

Bedrails: up or down.


THE AMERICAN Hospital of Paris.

THE AMERICAN Hospital of Paris.


A new twist in technician training.

A new twist in technician training.


A 10-year look at uniform cost accounting.


Electric typewriters can save time and money.


Teletype equipment can save time and lives.


Polling patients and personnel. II. What factors affect patients' opinions of their nursing care.


Environmental health safety.

Environmental health safety.


Environmental health and safety; wishing won't make it so; a good safety record calls for action; and maybe money.


Environmental health and safety; solvents, caustics, insecticides, bleaches; all are potential occupational hazards that can be overcome.


Environmental health and safety; radiation-helpful friend and deadly enemy.


Environmental health and safety; how to control food-borne disease in the hospital.


Purchasing; pneumatic and vertical conveyors.


The art of decision making.

The art of decision making.


Nonprofit hospitals and the corporate practice of medicine.


A flying visit to Municipal Hospital, Uranium City, Saskatchewan.


Personnel programs: a down-to-earth evaluation.


What personnel say about nursing care.

What personnel say about nursing care.


What we learned from a mass inoculation program.


Comparative testing of interior wall paints.


Pediatric units in practice.

Pediatric units in practice.


Hospital administration in Taiwan.

Hospital administration in Taiwan.


What hospitals have done to improve patient care.


Prepurchase testing of medical supplies.


What hospitals should know about investigational drugs; guiding principles in medical research involving humans.


The health of the nation.

The health of the nation.


What hospitals should know about investigational drugs; responsibilities of the hospital staff.


How work simplification can simplify purchasing.


Efficient utility service; planning for it starts with selecting the construction site.


Budget planning: how to prepare dietary budgets for smaller hospitals.


Poison control centers.

Poison control centers.


National clearinghouse for Poison Control Centers.


Four views of a visual aid department.

Four views of a visual aid department.


What the community expects of the hospital.


Emotional support and aid in financial planning: greatest needs in caring for the terminally ill.


Duties of the purchasing agent in planning for disaster.


A practical approach to lower laundry costs.


Budget planning: how to prepare dietary budgets for large hospitals.


Adenoviruses.

Adenoviruses.


Clinical observations with an oral nasal decongestant.


The evolution of pathology in Chicago.

The evolution of pathology in Chicago.


Promethazione hydrochloride for the control of nausea and vomiting during spinal anesthesia.


Virus-cell interrelationships.

Virus-cell interrelationships.


Ultran as a dermatological tranquilizer.


Clinical study: treatment of burns to control pain and infection.


Mongolism and metaphyseal aclasis.

Mongolism and metaphyseal aclasis.


An unusual cause of death.

An unusual cause of death.


Studies of immunity to Plasmodium berghei infection. I. The transmission of acquired immunity against P. berghei from female rats to their offspring.


D. D. T. water dispersible powders: studies on suspensibilty in relation to accelerated tropical storage treatment.


On two new piroplasms from the African mongoose, Helogale undulata rufula.


Investigation of filariasis problem in Ballia town (Uttar Pradesh).


Comparative efficacy of 50 per cent dieldrin-resin dispersible powder and 50 per cent dieldrin dispersible powder.


Studies on particle size distribution in relation to suspensibility. I. 50 per cent DDT water dispersible powders.


Description of a hitherto unknown structure in the mouth parts of mosquitoes.


Aquatic vegetation of Bokaro reservoir in relation to anopheline mosquito larvae and its control by application of herbicides.


Studies on Plasmodium berghei Vincke and Lips, 1948. XXIV. Selection of a chloroquine resistant strain.


Studies on Plasmodium berghei Vincke and Lips, 1948. XXV. The role of casein diet on the acquired immunity of mice infected with P. berghei.


Studies on the susceptibility of A. subpictus grassi, 1899 to chlorinated hydrocarbon insecticides in a Delhi state village.


Studies on Nuri strain of P. knowlesi. XIV. Pathological processes in the liver.


Detection of malaria parasites by concentration method.


Association of Chara zeylanica Willd. with anopheline breeding within Damodar-Eden canal area of West Bengal.


A note on the degree of susceptibility of A. culicifacies to D. D. T. in some parts of Bombay State.


A pilot study on the suspension of D. D. T. spraying and the setting up of a surveillance organisation in Kanara district covering the work up to October 31, 1956.


Filariasis in Assam State.

Filariasis in Assam State.


Studies on the rapid loss of biological efficacy of D. D. T. and dieldrin suspensions on mud surfaces against culicine mosquitoes.


Studies in the enzyme make-up of Pasteurella pestis. V. Dehydrogenase activity of virulent and avirulent strains.


Role of spleen in the maintenance of circulating leukocytes. IV. Effect of splenectomy on the myeloid elements of bone-marrow in albino rats.


Serum glycoprotein response during immunization. II. Effect of adequate antigenic stimuli (S. typhi).


Fibrin (horse) hydrolysate for parenteral administration.


Effect of electrical stimulation of the hypothalamus on menstrual cycle in monkey.


Hypothalamic control over oestrous cycle in the rat.


Effect of electrical stimulation of the hypothalamus on gastric secretory activity and ulceration.


Effect of electrical stimulation of the limbic system of brain (visceral brain) on gastric secretory activity and ulceration.


Relationship of male sex hormone to stress induced activation of adrenal cortex in rat.


Effect of castration on certain hematological data in male rat.


Studies on the role of methionine in the metabolism of tryptophane by rats treated with carbon tetrachloride.


Studies on the nutritional status of students of the Eden Hindu Hostel attached to Presidency College, Calcutta.


The electro-retinogram of bat and owl.

The electro-retinogram of bat and owl.


Effect of lipid intake on the serum protein and lipo-protein pattern in experimental atherosclerosis.


Pharmacological action of Lochnera rosea linn (Rattanjot).


The effect of oxyphenonium, hexamethonium and probanthine on the gastric acid secretion of rats.


Studies on thiaminase from fish. I. Properties on thiaminase.


Studies on thiaminase from fish. II. Effect of certain compounds on thiaminase activity.


Studies on blood cholesterol levels of healthy men of different socio-economic groups in India.


Studies on the blood of poor Indian new-born babies and their mothers.


Nutritive value of vegetable proteins. I. Protein efficiency ratios of cereals and pulses and the supplementary effect of the addition of a leafy vegetable.


Amino-acid composition of Indian foodstuffs. III. Threonine and arginine content of some cereals.


A method of estimation of bound nicotinic acid (BNA) in rice and wheat bran.


Influence of cooking of the nutritional value of foods. II. Riboflavin, nicotinic-acid and ascorbic-acid content of some cooked foods.


Ages of epiphyseal union in long bones of infenior extremity in U. P. subjects.


The mechanisms of nonponetrating injuries to the hollow abdominal viscera.


Cancer of the palate in coastal Andhra due to smoking cigars with the burning end inside the mouth.


Nardostachys Jatamansi DC: a phyto-chemical study of its active constituents.


Nardostachys Jatamansi DC: its sedative and depressant action as estimated by Warburg technique.


The influence of stretch stimuli on the chronotropic response of the frog's isolated whole heart and its individual chambers.


The effects of vagosympathetic and crescentic stimulation on the chronotropic and inotropic responses of intact and isolated frog hearts.


Familial cardiomegaly; case reports with review of literature.


Senile versus Huntington's chorea; two case reports.


Actinoluminescence analysis in histology.


Acute barbiturate poisoning; report of a case treated with picrotoxin.


Modern practice in immunization. VI. Tuberculosis immunization.


Symptomatic relief. VI. Vomiting in children.


The in vitro antibacterial activity of extracts from Enicostema littorale.


Pharmacological study of infected bajri cereal.


Effect of antibiotics on staphylophosphatase and staphylocoagulase.


Brevicollis: Klippel-Feil syndrome; case report.


Effect of the blockade of reticulo-endothelial system on tumor growth and metastasis; with a short review of literature.


Site of production of antibodies.

Site of production of antibodies.


Coagulation of blood.

Coagulation of blood.


Differential diagnosis of precordial pain.


Modern practice in immunization. 7. Pertussis immunization.


The problem of therapy in acute leukaemia.


A few thoughts on pediatrics in India.

A few thoughts on pediatrics in India.


The vascular architecture in foetus and infants. II.


Pneumonias in infancy and childhood.

Pneumonias in infancy and childhood.


Who practices industrial medicine? Results of a survey in Oklahoma.


Fatal pulmonary disease caused by an atypical acid-fast bacillus; a bacteriologic and clinical study.


Medical aspects of automation.

Medical aspects of automation.


Cutaneous reaction to fiberglas.

Cutaneous reaction to fiberglas.


Myocardial infarction in industrial workers; a study in their progress, performance, and prognosis after return to work.


Lung hernia.

Lung hernia.


Smoking habits and mortality among workers in cigarette factories.


JOHM J. PRENDERGAST, M. D., 1902-1957.

JOHM J. PRENDERGAST, M. D., 1902-1957.


Medical Department layout and design.

Medical Department layout and design.


Pre-employment x-ray survey of the lumbosacral spine in bus drivers.


Electrocardiographic survey of hotel employees in New York City.


Occupational hearing loss.

Occupational hearing loss.


The carcinogenic action of p-aminobiphenyl in the dog; final report.


Fatal silicosis with complicating infection by an atypical acid-fast photochromogenic bacillus.


The common cold; what is being done about it.


The value of early diabetes detection.

The value of early diabetes detection.


Toxicity of ozone. IV. Silicone aerosols and alcohol vapor therapy in ozone poisoning.


A classification system for lantern slides and other visual aids in occupational health.


The geography of food and cooking.

The geography of food and cooking.


Optimal nutrition of infants and children.


Food in the Armed forces.

Food in the Armed forces.


What I have learned in life.

What I have learned in life.


The place of reconstructive surgery in the prevention of foot ulceration in leprosy.


Medical management of ulcerative colitis.


HENRY E. SIGERIST.

HENRY E. SIGERIST.


The adventures of William Harvey, and of his discovery.


Padna and London; a Harveian tale of two cities.


THE LIFE of William Harvey.

THE LIFE of William Harvey.


Effect of BCG vaccination, lepromin testing and natural causes in inducing reactivity to lepromin and to tuberculin.


WILLIAM HARVEY: picture story.

WILLIAM HARVEY: picture story.


Treatment of trophic ulcers of leprosy with roniacol.


Traumatic injury in athletes.

Traumatic injury in athletes.


The study of the rebound pulse as a method of diagnosing papilledema.


Opthalmology around the world: letter from Paris.


Special problems of food and cooking today: psychiatry.


Detection of calcium in the skin lesions of lepromatous cases of leprosy by histochemical technique.


Science and the art of cooking.

Science and the art of cooking.


Significance of the relationship between the lepromin and tuberculin reactions in leprosy contacts; leprosy infection, leprosy disease, primary complex.


The role of electrophoresis in medicine.


Developmental anatomy of the foot.

Developmental anatomy of the foot.


Chlorpromazine as an adjunct in managing tuberculous patients.


Some nutritional and therapeutic aspects of wine and cognac.


Arterial supply of the foot.

Arterial supply of the foot.


FIELDS A Venous, lymphatic, and autonomic supply of the foot.


Foot problems: metabolic factors.

Foot problems: metabolic factors.


Foot pains.

Foot pains.


Significance of neuronal developmental and conditioned patterns in control of function of the foot.


Obstetric and gynecologic considerations of the foot.


Influence of a flexible outsole on the dynamics of the walking gait.


Orthopedic disabilities.

Orthopedic disabilities.


An appraisal of a new antiemetic drug: prochlorperazine.


The Hippocratic Oath.

The Hippocratic Oath.


How Hippocrates made his diagnoses.

How Hippocrates made his diagnoses.


Pharmaceutical research.

Pharmaceutical research.


The phrenotropic agents.

The phrenotropic agents.


Dextro-amphetamine sulfate in mild depression and anxiety.


Preliminary observations on the positive inotropic effects of mephentermine.


Prednisolone: a preliminary appraisal of its use topically.


Pseudopapilledema.

Pseudopapilledema.


Herpes zoster ophthalmicus.

Herpes zoster ophthalmicus.


Psychosomatic medicine and the general practitioner.


Recent advances in psychobiology and their impact on general practice.


An internist looks at psychosomatic disease.


The psychiatric management of duodenal ulcer.


Physiologic mediation of psychic stimuli in diabetes mellitus.


Psychiatric aspects of diseases of the eye, ear, nose and throat.


The management of anxiety in medical practice.


The psychosomatic conditions encountered in orthopedic practice.


An evaluation of prochlorperazine in the ambulatory treatment of psychiatric patients.


SYMPOSIUM on legal medicine.

SYMPOSIUM on legal medicine.


Medicolegal problems in physical medicine.


Suicide.

Suicide.


Pitfalls of defendants' examinations for insurance carriers.


Medicolegal problems of senility.

Medicolegal problems of senility.


Malpractice and rectal surgery.

Malpractice and rectal surgery.


Intramuscular administration of prednisolone in dermatoses; comparison with oral and topical therapy.


Azo gantrisin in the treatment of urinary tract infections.


Therapeutic value and limitations of an ataractic drug (rescinnamine).


The influence of stress conditions on the motility of human leukocytes.


Suicide; a review of the literature, 1945-1956.


Of arches and bridges.

Of arches and bridges.


Ferdinand Von Arlt and Ernst Fuchs; two representatives of the Vienna School of Ophthalmology.


Obesity--a psychosomatic dilemma.

Obesity--a psychosomatic dilemma.


Optometric control of medical practice through legislation.


Psychoanalytical aspects of the personality of the obese person.


Potentialities of group therapy for obesity.


A physiologist examines some psychiatric assumptions concerning obesity.


The influence of ACTH on the motility of human leukocytes.


Electroconvulsive therapy combined with chlorpromazine and reserpine.


The phrenotropic action of methyl-phenidylacetate hydrochloride.


Four medical vignettes from Turkey.

Four medical vignettes from Turkey.


The use of vitarespital in the treatment of elderly psychotic patients.


Respiratory disease in this century.

Respiratory disease in this century.


Malignant disease of the ethmoid and maxillary antrum.


The role of anatomical variations in the coronary arteries with particular emphasis upon intercoronary anastomoses.


A fascial key for exposing the glossopharyngeal nerve.


Survival after rupture of an aneurysm of the splenic artery during pregnancy.


MEMORIAL to the late Dr. Kirkpatrick.

MEMORIAL to the late Dr. Kirkpatrick.


CLINICAL report of the Rotunda Hospital; 1st November 1955 to 31st October 1956.


Coombe Lying-in Hospital, Dublin; clinical report for the year 1956.


NATIONAL Maternity Hospital, Dublin; clinical report.


Joseph Black and fixed air. II.

Joseph Black and fixed air. II.


Studies on two cases of blood transfusion reactions due to anti-E antibody.


Biochemical studies on Voges-Proskauer positive enteric bacteria.


Descriptions of the nymph and adult of Trombicula nagayoi Sada et al., 1950, and the taxonomic and ecological notes with the related species; studies on Tsutsugamushi, part 97.


Note on the taxonomical status of the mosquito, Uranotaenia bimaculata Leicester. (Diptera: Culicidae).


The Treponema pallidum agglutination test for syphilis: with special reference to antigen preparation.


Formation of hydrogen suifide by the decomposition of thiosulfate by bacteria. III.


Studies on the mechanism of ossification in tissue culture; some factors influencning the processes of ossification in the chick embryo femur.


Studies on the growth-promoting substance for fibroblasts in the simplified replicate tissue culture.


Cultivation of liver cells from chick embryos in the simplified replicate tissue culture.


Experimental studies on hepatitis virus of mice in tissue culture.


Spike duration in single myelinated nerve fibres.


Anode break excitation in single myelinated nerve fibres.


Accommodation of the human retina to exponentially increasing currents.


The effects of calcium ions upon the size of the action current of single myelinated nerve fibres of the toad.


Comparisons of ventilatory capacities among fishing divers, nurses, and telephone operators in Japanese females.


Effects of strychnine on the intracellular potentials of spinal motoneurons of the toad.


The effect of calcium ions on electrical properties of striated muscle fibres.


The effect of activity of reticuloendothelial system on threshold of b-wave of ERG of dark adapted rabbit eye.


Motor response of the stomach and small intestine caused by stimulation of the peripheral end of the splanchnic nerve, thoracic sympathetic trunk and spinal roots.


A study on the origin of intraretinal action potential of the cyprinid fish by means of pencil-type microelectrode.


Nervous activities of the stretch receptor in the toad's sartorius muscle.


Behaviors of cervical muscles in labyrinthine and skin-pressure reflexes.


Predominance of right-handed spirals in the interaepidermal sweat ducts in man and the primates.


Studies on neuronal processes in the retina by antidromic' stimulation.


Adrenal cortical activity in hydrated and dehydrated rats.


Effects of vagotomy on the excitability of the respiratory center to blood CO2.


Comparative studies on the catalatic reaction between red cell suspension and hemolysate.


On red cells fixed by H202.

On red cells fixed by H202.


Notes on the shape of red blood corpuscle.


Effects of Thoulet's reagent on the glycerinated muscle fiber.


Further studies on the wave-length of impulse in relation to some physiological constants.


On the transforming action of the brain shown in the brain wave.


The alkaline phosphatase activities in the isolated nuclei of ox retina.


Properties of the procaine end-plate potential.


Phylogenetic studies on miniature electrical oscillation in insect muscles.


Role of vasopressin in the release of ACTH.


Effects of Thoulet's reagent on actomyosin and its component proteins.


Na and K contents of retina of toad and electroretinogram.


Fibrillation of muscle fibers produced by ammonium ions and its relation to the spontaneous activity at the neuromuscular junction.


A pyrogenic substance in blood plasma of equine encephalomyelitis.


[Cycloserine in the treatment of pulmonary tuberculosis; experience at the Hospitais Civis de Lisboa].


Range of movement of the mandible.

Range of movement of the mandible.


Multiple ossifying periapical fibroma; diagnosis and surgery.


Marginal fit of direct acrylic restorations.


Incidence of clinical manifestations of periodontal disease in light of oral hygiene and calculus formation.


The temporomandibular joint: function, dysfunction and dental treatment.


A precision and biologic root canal filling technic.


Buffer effect of saliva stimulated between and at meals.


Practical value of comparative roentgenography of the temporomandibular joint.


Bleaching of the discolored pulpless tooth.


Dental prosthesis in the past.

Dental prosthesis in the past.


Dental education in Turkey.

Dental education in Turkey.


Dental house staffs at civilian hospitals, 1950-56.


Transplantation of teeth: clinical and experimental studies.


Efficient office routines.

Efficient office routines.


Our basic responsibilities.

Our basic responsibilities.


The art in casting a hollow pontic.

The art in casting a hollow pontic.


EDUCATIONAL requirements and a program of certification for dental laboratory technicians.


SUPPLEMENT to list of certified dental materials.


CHANGES in the distribution of dentists during 1954-1956.


The psychology of weight reduction.

The psychology of weight reduction.


Changing attitudes toward overweight and reducing.


The father's influence on young children's food preferences.


Food acceptance by soldiers under an ad libitum regimen.


Management training pays dividends.

Management training pays dividends.


Employee training.

Employee training.


Bacterial growth in poultry stuffings.

Bacterial growth in poultry stuffings.


ANNOTATED bibliography on disaster feeding.


Emergency mass feeding in a Hungarian refugee camp.


After hurricane Audrey; mobile feeding.

After hurricane Audrey; mobile feeding.


Massive hemorr'age from peptic ulcer: a cause of myocardial infarction in the aged.


Immunity to the afflictions of old age.

Immunity to the afflictions of old age.


Clinical studies in geriatrics. III. The tonic.


The use of perphenazine (trilafon) to control anxiety and agitation in aged patients.


Conservative management of the osteoarthritic knee.


Occupational therapy for geriatric patients in a mental hospital: therapeutic possibilities and limitations.


The health of the nation.

The health of the nation.


Severe diabetic acidosis treated with the artificial kidney; report of a case complicated with acute renal failure.


The future of hemodialysis in military medicine.


Urinary findings diagnostic of pyelonephritis.


Unilaterl renal disease and hypertension; report of three successfully treated cases.


Cervical disk lesions.

Cervical disk lesions.


Surgical treatment of cardiospasm (achalasia of the esophagus); considerations of aspects of esophagomyotomy.


Triethylenephosphoramide in the treatment of disseminated melanoma.


Tabulation and review of autopsy findings in fifty-five paraplegics.


Obstructive water-losing uropathy.

Obstructive water-losing uropathy.


CHLORAMBUCIL.

CHLORAMBUCIL.


Detection of glycosuria in pregnancy; comparative study of glucose oxidase and copper reduction techniques.


DIETHYLCARBAMAZINE citrate, U.S.P.

DIETHYLCARBAMAZINE citrate, U.S.P.


TETRACYCLINE phosphate complex.

TETRACYCLINE phosphate complex.


USE OF heparin sodium in hyperlipemia.

USE OF heparin sodium in hyperlipemia.


Medical insurance. I. What doctors think about it.


Mechanical correlation of data in differential diagnosis of hematological diseases.


Degree of physical dependence induced by secobarbital or pentobarbital.


Choice of a diuretic agent based on pharmacological principles.


Treatment of essential hypertension with chlorothiazide (diuril); its use alone and combined with other antihypertensive agents.


Evaluation of chlorothiazide (diuril) in the toxemias of pregnancy; analysis of one hundred forty-four patients.


The special problem of rheumatic heart disease in pregnant women.


Effect of chlorothiazide on electrolyte transport in man; its use in the treatment of edema of congestive heart failure, nephrosis, and cirrhosis.


Three-way therapeutic effectiveness of tar-steroid cream.


Immunization of infants with poliomyelitis vaccine; guest editorial.


The clinical significance of hematuria.

The clinical significance of hematuria.


Diseases of the female urethra.

Diseases of the female urethra.


The solitary circumscribed pulmonary nodule; study of seven hundred five cases encountered roentgenologically in a period of three and one-half years.


Providing a steady state for cardiac catheterization under anesthesia.


Fractures of the elbow in children; review of three hundred consecutive cases.


Surgical treatment of carcinoma of the lung; evaluation of six hundred ninety-nine cases from 1933 through 1956.


Diagnostic significance of fulness in the ear.


Radiation dose to gonads from diagnostic x-ray exposure.


Retrograde leg-milking test for varicose veins; a simple method for localization of incompetent perforators.


Recognition and management of problems associated with prediabetes during pregnancy.


Nutrition and joint disease.

Nutrition and joint disease.


Cutaneous eruptions after use of Salk poliomyelitis vaccine.


USE OF pooled plasma as a medicolegal hazard.


Footsteps on the Frontier some observations on the third party in medicine.


Use of relaxin in the treatment of scleroderma.


Myocardial infarction in a one-year industrial study.


Roentgen evidence of normal heart and congenital abnormality in early infancy.


Production of controllable apnea in anesthesia; combined use of narcotic analgesics and their antagonists.


Lobar emphysema.

Lobar emphysema.


Facilitating locomotion in neurological disease of lower extremities; description of a new appliance.


Dextran and prolonged bleeding time; results of a sixty-gram, one-liter infusion given to one hundred sixty-three normal human subjects.


Tracheotomy in the treatment of severe mediastinal emphysema.


Current status of therapy in bacterial endocarditis.


The problem of spatial disorientation.

The problem of spatial disorientation.


Method of radiologic diagnosis of congenital heart disease in children.


Multiple screening in evaluation of entering college and university students.


Abdominal crises with urologic implications.


Amnesia-analgesia for management of children too young to cooerate; method for use during cardiac catheterization and other procedures.


Pediatric surgery is growing up.

Pediatric surgery is growing up.


Cervical lymphadenopathy, fever, and coma.


Respiratory deaths associated with Asian influenza epidemic; report of twenty-three cases.


Rupture of the marginal sinus of the placenta.


Comprehensive or single plan major medical insurance.


Clinical experience with streptokinase administered buccally; treatment of infection and edema.


THE REPORTING of disease.

THE REPORTING of disease.


Choriocarcinoma in mother and infant.

Choriocarcinoma in mother and infant.


Hemangioma of posterior mediastinum with cord compression in midthoracic region; multiple-stage operations with postoperative improvement.


Cardiac arrest; successful treatment in a patient's room.


CANCER AND viruses.

CANCER AND viruses.


Chemotherapy of leukemia and lymphoma.

Chemotherapy of leukemia and lymphoma.


Surgery and the geriatric patient.

Surgery and the geriatric patient.


Ataxic form of poliomyelitis.

Ataxic form of poliomyelitis.


Some aspects of cholesterol metabolism.

Some aspects of cholesterol metabolism.


An unusual cause of intussusception; report of a case.


DIAGNOSIS and treatment of malignancies; a panel discussion.


The surgical tolerance of the cardiac patient; a review of 143 cases.


Portraits honor medical women.

Portraits honor medical women.


Sterilization of ampuls for spinal anesthesia.


Certain characteristics of the normal single motor unit.


Routine use of the lateral roentgenogram for peptic ulcer visualization.


Cystoscopic management of ureteral calculi.


Obstetric analgesia with promazine.

Obstetric analgesia with promazine.


Intestinal rupture of the newborn; report of three cases.


The problem of tennis elbow; a review.

The problem of tennis elbow; a review.


Ileal obstruction in infants and children; presentation of three cases.


The hospital staff and iatrogenic morbidity and mortality.


Bioliotherapy.

Bioliotherapy.


Fractures of the tibial plateau.

Fractures of the tibial plateau.


Osteopathic education.

Osteopathic education.


Symposium: renal tumors.

Symposium: renal tumors.


The analytic treatment of schizophrenia.


Hematuric in infants and its significance.


Admission procedures at the College of Osteopathic Physicians and Surgeons.


The rural clinics program of the Kirksville College of Osteopathy and Surgery.


The diphasic actions of ceanothyn and EDTA as blood coagulants.


Sorption of water by rubber closures for injections. II. Effects of vapor pressure, bisulfite, and washing treatments.


In vitro study of gastric antacids.

In vitro study of gastric antacids.


Piperidines with motor depressor and anti-inflammatory properties.


Hemopoietic effects of ferriferrocobaltochloroaminoacetate (L. B. 101) a cobalt-iron complex.


Hypotensive activity of a new ganglionic blocking agent and its comparative effectiveness on normotensive unanesthetized dogs.


The preparation and pharmacological properties of some chloral derivatives.


Sorption of water by rubber closures for injections. III. Effect of organic compounds.


Diisocyanates in the characterization of alcohols.


Amine derivatives of cyanuric chloride. III. Piperazines and ethylenediamines.


Derivatives of alpha-amino aldehydes. III. Cyclization products of thiosemicarbazones.


Haze formation of rubber closures for injections.


Plasma levels of mephenesin, mephenesin carbamate, guaiacol glyceryl ether, and methocarbamol (AHR-85) after oral and intravenous administration in the dog.


A synthesis of diketopiperazines using polyphosphoric acid.


Carvone analysis by ultraviolet absorption.


Some thyroxine analogs. I. Substituted betaphenylserines and related substances.


A chromatographic-densitometric procedure for analysis of the solanaceous alkaloids.


A pharmacognostical study of Datura discolor Bernh.


The effect of ceanothyn on blood coagulation time.


Sulfaethylthiadiazole. I. Interpretations of human blood level concentrations following oral doses.


Sulfaethylthiadiazole. II. Distribution and disappearance from the tissues following intravenous injection.


Syntheses of isoquinoline derivatives using 1-(lithio methyl) isoquinoline.


Cardiac glycosides of Euonymus atropurpurea Jacq. II. A study of the structure of euatroside and euatromonoside.


A study of the lyophilization of several pharmaceutical gums and suspending agents.


5-Hydroxytryptamine antagonism by lysergic acid diethylamide after intracerebral injection in conscious mice.


The quantitative estimation of ergotamine and ergotoxine by paper chromatography.


The preservation of aqueous preparations containing nonionic surfactants. I. Growth of microorganisms in solutions and dispersions of nonionic surfactants.


Isotonic solutions. V. The permeability of red corpuscles to various salts.


Effect of glutathione and some of its components on the response of Escherichia coli to penicillin.


Amithiozone (tibione) analogs.

Amithiozone (tibione) analogs.


The preservation of aqueous preparations containing nonionic surfactants. II. Preservative studies in solutions and products containing nonionic surfactants.


The sterilization of plastic intravenous injection equipment by ethylene oxide vapor.


A note on the crystallography of carbutamide (BZ-55).


The effect of reserpine and meprobamate on gastric acid secretion.


The solubility and complexing properties of oxytetracycline. I. Interaction in aqueous solution.


Studies to determine the adaptability of the staircase phenomenon to the assay of cardiac glycosides.


Isolation of a saponin, hederin, and its sapogenin, hederagenin, from bur clover (Medicago hispida).


A pharmacological study of a new orally effective adrenergic blocking agent (A-2077).


Studies on the high voltage electrophoresis of strychnos alkaloids.


Effect of flavors upon the stability of penicillin in oral penicillin-triple sulfonamide powders.


Adsorption studies on clays. I. The adsorption of two alkaloids by activated attapulgite, halloysite, and kaolin.


Adsorption studies on clays. II. The adsorption of bacteria by activated attapulgite, halloysite, and kaolin.


An apparatus for testing the effect of drugs on the spontaneous activity of the rat.


The quantitative measurement of 1-phenylephrine hydrochloride in dilute aqueous solution.


Adsorption studies on clays. III. The adsorption of diphtheria toxin by activated attapulgites, halloysite, and kaolin.


A note on the crystallography of alstonidine.


A note on the root bark alkaloids from Alstonia constricta F. Muell.


Alstonia alkaloids. VII. The structure of alstonidine.


Iodophors as disinfectants.

Iodophors as disinfectants.


A note on the assay of zinc stearate.

A note on the assay of zinc stearate.


Surfactants in tablets to improve disintegration.


Effect of alterations in side chain upon anti-inflammatory and liver glycogen activities of hydrocortisone esters.


Stability of atropine in aqueous solution.


Enzymatic decomposition of Digitalis glycosides.


Antimicrobial properties of a series of beta-piperidinopropiophenones and related derivatives.


An investigation of the incompatibilities of quaternary ammonium germicides in compressed troches. I. The adsorption of cetylpyridinium chloride and benzalkonium chloride by talc and kaolin.


A comparative human in vivo study of antacids.


Alkoxy derivatives of beta-piperidinopropiophenone and related compounds.


A new accurate and reliable method to record blood coagulation time using an A. C. bridge principle.


Comparative in vivo methods for evaluating antacids in humans.


Studies with a uterine antispasmodic, ambucetamide.


An investigation of the possible potentiation of the analgetic properties of morphine by mephenesin.


A method for the measurement of lubricating property of medicinal products.


Viscosity changes of sodium alginate solutions after freezing and thawing.


A note on the effect of boric acid and sodium metaborate on the oxygen uptake of brain tissue.


A note on crystallographic and x-ray diffraction data for ethinamate.


A note on mathematics of oral sustained release products.


A comparative study of the metabolism in the human body of some isomers of tartaric acid.


Preparation of metal salts of alkanesulfonic acids.


The electron sterilization of certain pharmaceutical preparations.


Prediction of stability in pharmaceutical preparations. IV. The interdependence of solubility and rate in saturated solutions of acylsalicylates.


The solubility and complexing properties of oxytetracycline and tetracycline. II. Interactions in Nonaqueous solution.


The comparative antispasmodic activity of N-methyl-3-piperidyl diphenylglycolate methobromide (JB-340) and atropine sulfate.


An evaluation of certain hypotensive agents. I. Diquaternarized amino alcohol esters of piperidinecarboxylic acids and a pyridinecarboxylic acid.


An evaluation of certain hypotensive agents. II. Acetylenic bis-onium derivatives.


A simplified nitrite procedure for the determination of reserpine.


Ultrasonic depolymerization of natural polymers.


Antibacterial and antifungal properties of beta-naphthol derivatives. IV.


Solution rate of theophylline salts and effects from oral administration.


Study of complex formation by polyethylene glycol and dimethylurea with some pharmaceuticals.


A colorimetric assay for chlorobutanol.

A colorimetric assay for chlorobutanol.


A note on paper chromatography of quaternary ammonium salts.


Erroneous values for sodium and potassium content of rat tissues dry-ashed in Pyrex.


A note on the use of sorbitol solution in pharmaceutical formulations.


Some applications of an integrating sphere reflectometer to pharmaceutical problems.


Methods for the determination of tral, a new anticholinergic drug.


The determination of theophylline, pentobarbital, and papaverine in tablets by spectrophotometric analysis.


The synthesis of 1-S-35 diamox.

The synthesis of 1-S-35 diamox.


The activity of beta-diethylaminoethyl diphenylpropyl-acetate hydrochloride on Ehrlich ascites and other tumors.


The effect of various sugars and polyols on the stability of vitamin B12.


A potent pyrogenic extract derived from a strain of Aerobacter aerogenes.


Steroidal sapogenins. XLIII. Survey of plants for steroidal sapogenins and other constituents.


A rapid chromatographic assay of acetylsalicylic acid, acetophenetidin, and caffeine.


Triazine mercurial diuretics.

Triazine mercurial diuretics.


Investigation and development of protective ointments. I. Development of a method for measuring permeation of mechanical barriers.


Investigation and development of protective ointments. II. Influence of partition coefficient and thickness.


A note on the psychomotor effects of diphenhydramine hydrochloride and dimenhydrinate.


A note on the in vitro inhibition of Endamoeba histolytica by diazobarbituric anhydride.


A note on the volatile oil from the roots of Pteryxia terebinthina (Hook.) Coult. and Rose var. Terebinthina.


A comparison of in vivo and in vitro tests for the absorption, penetration, and diffusion of some medicinals from silicone and petrolatum ointment bases.


A cylinderplate method for the quantitative determination of diffusion of antibacterial drugs from ointments.


Paper chromatographic evaluation Rauwolfia species.


Spectrophotometric titrations with nitrous acid. I. The estimation of procaine hydrochloride, propoxycaine hydrochloride, and tetracaine hydrochloride.


Spectrophotometric determination of cycloserine and isoniazid in pharmaceutical preparations.


A dilatometric study of melting behaviors of some fats, waxes, and related substances of pharmaceutical importance. I. Polyethylene glycols, spermaceti, cetyl alcohol, petrolatum, white wax, and theobroma oil.


Isonicotinoyl hydrazine derivatives and their activity against Mycobacterium tuberculosis in the mouse.


A colorimetric procedure for imidazolines.


Reaction of Rauwolfia alkaloids, indoles, and related compounds to nitrite.


The antineoplastic action of chemical fractions of the fruit of Citrulius colocynthis on sarcoma-37.


Certain metallic soap-petrolatum ointment bases.


Studies on the purity of dimercaprol (BAL).


A rapid determination of the relative purity of vitamin B12 (cyanocobalamin) in pharmaceutical products.


The metabolic fate of a hexamethylenimine analgesic.


The study of the effect of certain chemicals on perspiration flow.


The synthesis and aerosol formulation of certain rare earth compounds as potential antiperspirants.


A study of dispersion with ultrasound. I.


A study of dispersion with ultrasound. II.


The calibration and use of direct reading isotomeity meters.


Cyanocobalamin (vitamin B12). II. Further studies of the effect of ascorbic acid degradation products on cyanocobalamin.


The effect of certain additives on the gel point of methylcellulose.


The determination of chlorobutanol in pharmaceuticals by amperometric titration.


The chromatographic separation and determination of diphenylhydantoin and phenobarbital.


Analysis of poison ivy fruit fat.

Analysis of poison ivy fruit fat.


A study of moisture vapor transmission through closures.


The effect of orally administered sodium iodide and sodium iodate on blood sugar response to thiourea in rats.


A study of the effect of lubricant and fines on a tablet granulation.


Correlation of molecular refraction with structure in the terpene series.


Studies on the effects of ephedrine in the presence of cocaine.


Anticonvulsant activity of pyrazole and of pyrazole with aliphatic substitutions at the three position.


Nitro-organophosphorus compounds. I. Phosphite and phosphate esters of 2-nitro-2-methylpropanol-1.


The complement-fixation test in diagnosis of eperythrozoonosis in swine.


The use of a therapeutic shampoo in small animal dermatoses.


ET-57 (Trolene) for demodectic mange; a case report.


Diagnosis of leptospirosis from urine specimens by direct culture following bladder tapping.


The incidence of anaplasmosis in Wyoming.


Comments on veterinary practices by a laymen's advisory committee.


Chemotherapeutic control of experimental babesial and anaplasmal infections in cattle in Brazil.


Technique of preparing frozen semen.

Technique of preparing frozen semen.


Some effects of hygromycin on early natural infections of Ascaris lumbricoides in swine.


Abnormal urogenital tract of a ram.

Abnormal urogenital tract of a ram.


The so-called downer cow syndrome.

The so-called downer cow syndrome.


Iridocyclitis and cataracts associated with an encephalomyelitis in chickens.


Extreme mortality in Hjarre's disease (Co-ligranuloma) in chickens.


A comparison of beagles released for private ownership with those maintained under kennel conditions.


The natural occurrence of Leptospira pomona in an opossum; a preliminary report.


A comparison of the California and Whiteside mastitis tests.


A survey of gastrointestinal nematodes in feeder calves in Southern illinois.


Trimar anesthesia for cats.

Trimar anesthesia for cats.


A new type of artificial vagina and a new collection technique for boar semen.


Passive immunity to hog cholera in nursing pigs.


Intramuscular treatment of staphylococcic mastitis with neomycin sulfate and polymyxin B sulfate.


An experiment to produce coronary occlusion in the dog.


An electrical apparatus and its application in defibrillating the heart of the dog.


Congenital porphyria (pink tooth) in HolsteinFriesian calves in California.


Thoracic disorders in the cat.

Thoracic disorders in the cat.


Ulcerogenic cerebral lesions and pancreatic tumors.


Chemotherapy of the leukemias and lymphomas.


The problem of the oversize infant.

The problem of the oversize infant.


Gynecology.

Gynecology.


The local use of corticosteroids in orthopaedics.


Further measurements with the Leiden telecobalt unit.


A polynucleotide coenzyme of oxidative phosphorylation.


A rapid method for measuring phosphorylation coupled to the oxidation of reduced diphosphopyridine nucleotide.


A polynucleotide coenzyme of oxidative phosphorylation. II.


Urinary metabolites of caffeic and chlorogenic acids.


Metabolism of adenine in mice.

Metabolism of adenine in mice.


Separation of thyrotropic hormone from a pepsin inhibitor.


On the esterolytic activities of papain and trypsin.


Steroid isolation studies in congenital adrenal hyperplasia.


The cleavage of beta-ketoadipic acie by Neurospora crassa.


Some inhibitory properties of carbamyl phosphate.


The conversion of lysine to hydroxylysine and its relation to the biosynthesis of collagen in several tissues of the rat.


Some properties of beef spleen phosphoamidase.


Enzymatic synthesis and characterization of a new trisaccharide, alpha-lactosyl-beta-fructofuranoside.


Phospholipides containing amino acids other than serine. I. Detection.


The enzymic interconversion of uridine diphosphogalactose and uridine diphosphoglucose.


Studies on pituitary lactogenic hormone. XVI. Molecular weight of the ovine hormone.


Studies on pituitary lactogenic hormone. XVII. Oxidation of the ovine hormone with performic acid.


Galactose metabolism in rat liver slices.


The decarboxylation of amino acids, proteins, and peptides by N-bromosucclnimide.


Urinary steroid excretion after total adrenalectomy. III. Isolation and identification of the metabolites of cortisone acetate.


Hemoglobin catabolism. I. Glutathione peroxidase, an erythrocyte enzyme which protects hemoglobin from oxidative breakdown.


The metabolism of p-methoxyphenylalanine and p-methoxyphenylpyruvate.


Preparative isolation of amino acids by carrier displacement chromatography on ion exchange resins.


The oxidation of 2-nitropropane by extracts of pea plants.


The identification of 6-succinoaminopurine and of 8-hydroxy-7-methylguanine as normal human urinary constituents.


Trypsin activation of a ferricyanide-linked pyruvic acid oxidation.


Oxidation of reduced triphosphopyridine nucleotide and associated phosphorylation.


Physical and chemical properties of protamine from the sperm of salmon (Oncorhynchus tschawytscha).


Ryegrass nucleases.

Ryegrass nucleases.


Isocitritase; enzyme properties and reaction equilibrium.


An enzymatic method for the determination of formic acid.


Skin sterols. XIII. Incorporation of acetate into various sterols by skin slices.


Study of carbamyl phosphate-ornithine transcarbamylase.


Comparison of the decomposition properties of compound X and carbamyl phosphate.


The assay of glucagon and epinephrine with use of liver homogenates.


Studies on succinic dehydrogenase. IV. Activation of the beef heart enzyme.


Inhibition of lactic acid dehydrogenase by fluoropyruvic acid.


Studies on the autocatalytic activation of trypsinogen.


The relation of dietary pyridoxine to the 5-hydroxytryptophan decarboxylase activity of rat kidney.


The succinate-glycine cycle. II. Metabolism of delta-aminolevulinic acid.


The incorporation of glycine into globin and the synthesis of heme in vitro in duck erythrocytes.


Evidence for the spatial configuration of hydroxyaspartic acid.


The use of countercurrent distribution for the study of radiochemical purity.


The conversion in vivo of xylitol to glycogen via the pentose phosphate pathway.


Synthesis of phenylacetylglutamine by human tissue.


Terminal amino acids of rhodopsin.

Terminal amino acids of rhodopsin.


The reaction of O-methylisourea with bovine pancreatic ribonuclease.


2-Methoxyestrone, a new metabolite of estradiol-17 beta in man.


Metabolism of 11 beta-hydroxy-delta 4-androstene-3,17-dione in man.


The component fatty acids of Neurospora crassa lipides.


Amino acid incorporation by intact and disrupted ribonucleoprotein particles.


Central fractures of the acetabulum.

Central fractures of the acetabulum.


The Kuntscher method of intramedullary fixation.


Electrical burns of the upper extremities.


Osteotomy-bunionectomy for hallux valgus.


Shortening of the metatarsal shaft in the treatment of plantar keratosis; an end-result study.


Clinicopathological study of ninety-four limbs amputated for occlusive vascular disease.


Open grafting of raw surfaces of the hand.


Sensory disturbances in the hands of children with cerebral palsy.


Fusion of the spine for tuberculosis in children; a long-range follow-up study.


Cervical intervertebraldisc calcification in children.


Arthrodesis of the hip with staple fixation.


Central (medullary) fibrosarcoma of bone.


Biochemical studies of articular cartilage. I. Normal values.


Biochemical studies of articular cartilage. II. Values following the denervation of an extremity.


Electron microscopy of epiphyseal and articular cartilage matrix in the femur of the newborn infant.


Kinetics of strontium metabolism in man.


Radiation sterilization of homogenous-bone transplants utilizing radioactive cobalt; preliminary report.


A brace for correction of torsion of the lower extremity.


Progressive diaphyseal dysplasia (Engelmann's disease); report of a case with twenty-two-year follow-up.


Sterling Bunnell; in appreciation.

Sterling Bunnell; in appreciation.


LORD NUFFIELD; great benefactor of orthopaedic surgery eightieth birthday.


Arthroplasty of the hip.

Arthroplasty of the hip.


The direct approach to congenital dislocation of the hip.


Slipped upper femoral epiphysis; characteristic of a hundred cases.


The results of treatment of slipped femoral epiphysis.


The use of tibilis posterior as a dorsiflexor.


March gangrene; ischaemic myositis of the leg muscle from exercise.


Metaphysial fractures in infancy.

Metaphysial fractures in infancy.


Arthritis of hip complicating osteitis pubis.


Chondroblastoma (Codman's tumour) of the thoracic spine.


The relief of traumatic arterial spasm in threatened Volkmann's ischaemic contracture.


The role of abdominal pressure in relieving the pressure on the lumbar intervertebral discs.


Dislocation of the shoulder complicated by complete rupture of the axillary artery; successful suture of the artery in an eighty-seven-year-old man.


Posterior dislocation of the shoulder.

Posterior dislocation of the shoulder.


Excision of the coccyx for coccydynia; a study of the results in twenty-eight cases.


Longitudinal osteotomy of the tibia (the "Reed" osteotomy).


Fracture-dislocation of the lumbar spine; report of an unusual case.


Radial nerve in osseous tunnel at humeral fracture site diagnosed radiographically.


Foramen in the humerus caused by the median nerve.


Variations in joint space of the hip as shown radiographically.


Oligodactyly.

Oligodactyly.


An adaptor for extracting McLaughlin nails.


A simple traction harness for cervical manipulation.


The effect of bone bank preservation on the calcifying mechanism.


Vascular changes after interference with the blood flow of the femoral head of the rabbit.


Intracellular potentials in pacemaker and integrative neurons of the lobster cardiac ganglion.


Physiological effects of carbohydrates in the nutrition of a mosquito, Aedes aegypti and two flies, Sarcophaga bullata and Musca domestica.


The adsorption of lipids from the erythrocyte surface by silica and alumina.


Our experience with tuberculosis of the spine at the Wanless Hospital, Miraj, India.


Some thoughts on prevention of obstetrical emergencies.


Adenosinetriphosphatase in the mitochondria of unfertilized and newly fertilized sea-urchin eggs.


Membrane resting and action potentials from a protozoan, Noctiluca scintillans.


Further observations on the treatment of typhoid fever with a combination of chloramphenicol and one of the tetracyclines.


Helpful hints for your pharmacist.

Helpful hints for your pharmacist.


The importance of a general recovery room.


Pulmonary sarcoidosis; a physiopathologic analysis.


The serum transaminase test in various diseases; its diagnostic value in liver disease.


The action of ultrasound on the mouse liver.


Postural blood pressure changes in the elderly.


Membrane potential changes and ion movements in the frog sartorius muscle.


A home care rehabilitation program for ex-urban communities.


The effect of carbon dioxide on human red cells in vitro.


Excretion of nitrogen by the alligator embryo.


The prevalence of diseases of the heart in an urban center as estimated from medical examination of a probability sample.


Acquired immunity in tuberculosis.

Acquired immunity in tuberculosis.


The Western Reserve approach to teaching medical students about long-term illness.


Mitrochondrial and cytoplasmic protease activity in sea urchin eggs.


The role of humidity in the differentiation of the celular slime molds.


A comparative study on spectral sensitivity in tadpoles and adult frogs.


Hyperosmolarity in adults: a critical review.


Application of cohort analysis to the study of time trends in neoplastic disease.


Differentiation of the antilipids occurring in nontreponemal diseases and syphilis.


What shoud be tell the patient.

What shoud be tell the patient.


Renal hemodynamic studies in patients with extensive paralysis; the influence of weight loss, muscle atrophy, and immobilization.


Cystic fibrosis of the pancreas.

Cystic fibrosis of the pancreas.


Urinary estrogen excretion in Cushing's syndrome.


Eunuchoidism with low urinary follicle-stimulating hormone in the female: comparison with this syndrome in the male and with the premenarchal menopause.


The metabolism of epinephrine-containing isotopic carbon in man.


Metabolism of free and conjugated 17-hydroxycorticosteroids in subjects with uremia.


Plasma 17-hydroxycorticosteroid levels in patients with abnormal glucose tolerance during pregnancy.


Oxytocin in lactating and nonlactating women.


The reversibility of osteoporosis in Cushing's disease; case report.


Thyroid function in subacute thyroiditis.


Some aspects of thyroidal iodine metabolism in a case of iodine-induced hypothyroidism.


Persistent thyroid carcinoma.

Persistent thyroid carcinoma.


The plasma proteins in thyroid disorders.


Metabolism of progesterone by adrenal tissue from patients with Cushing's syndrome and mammary carcinoma.


Jaundice during administration of methylestrenolone.


The effects of experimental hepatobiliary disease on certain aspects of tocopherol metabolism in the rat.


Studies of the satiety response in mice.


Blood adrenocorticotrophic hormone and plasma corticosteroids in men exposed to adverse environmental conditions.


Toxicity and blood ammonia rise resulting from intravenous amino acid administration in man: the protective effect of l-arginine.


Effects of posture and atropine on the cardiac output.


Capillary observations in patients with hemorrhagic fever and other infectious illnesses.


Unbound amino acid concentrations in human blood plasmas.


The pressure-volume responses of human forearm veins during epinephrine and norepinephrine infusions.


The mechanical behavior of the lungs in healthy elderly persons.


Plasma adrenocorticotrophic hormone in Addison's disease and its modification by the administration of adrenal steroids.


The effect of pulmonary vascular pressures on the mechanical properties of the lungs of anesthetized dogs.


Serum iron levels in siderosis due to habitually excessive iron intake.


The binding of cations by chondroitin sulfate.


Pregnane 3 alpha, 17 alpha, 20 alpha-triol and pregnane-3 alpha, 17 alpha, 20 alpha,-triol-11-one excretion by patients with adrenocortical dysfunction.


A cause of the thrombocytopenia and leukopenia that occur in dogs during deep hypothermia.


Comparison of various procedures for determining sucrose and inulin space in the dog.


Studies of visceral pain: measurements of stimulus intensity and duration associated with the onset of pain in esophagus, ileum and colon.


The absorption of glycine and its conversion to serine in patients with sprue.


The effects of acutely increased systemic resistance on the left atrial pressure pulse: a method for the clinical detection of mitral insufficiency.


A tandem foream plethysmograph for study of acute responses of the peripheral veins of man: the effect of environmental and local temperature change, and the effect of pooling blood in the extremities.


Hexosamines of seromucoid.

Hexosamines of seromucoid.


Hyaluronate in normal human synovial fluid.


The effect of desoxycorticosterone acetate on water and electrolyte distribution.


The ultrafiltrable calcium of human serum. II. Variations in disease states and under experimental conditions.


Correction by defects in clotting accelerator activity by administration of methionine and vitamin K and of a new sulfhydryl-substituted methylnaphthoquinone, vitamin K-S(II).


Ventilatory mechanics in pulmonary edema in man.


The effect of acetylcholine on the human pulmonary circulation under normal and hypoxic conditions.


The influence of dietary carbohydrate deprivation on the metabolism of intravenously administered fructose and glucose in man.


Content and composition of the mucoprotein fraction of human serum (seromucoid) in disease with special reference to hematologic disorders.


Histochemical studies of succinic dehydrogenase and cytochrome oxidase of the rabbit brain, with special reference to the results in the paraventricular structures.


Corticospinal tract of the cat: an attempt to correlate the pattern of degeneration with deficits in reflex activity following neocortical lesions.


Certain anatomical and functional interrelations between the tegmentum of the midbrain and the basal ganglia.


The contribution of individual thoracic spinal nerves to the upper cervical sympathetic trunk.


Brainsten-induced eye movements in cats.


The role of the septal nuclei and components of the fornix in the behavior of the rat.


Effect of the cessation of thiouracil administration on the cell population of the thyroid of rats.


The development with age of hypothalamic restraint upon the appetite of the rat.


The localization of neurosecretory structures and pathways in the male albino rabbit.


An evaluation of a chemical method for the estimation of oestriol, oestrone and oestradiol-17 beta in human urine.


Metabolic effects of three testosterone derivatives including 17 alpha-ethyl-19-nortestosterone.


Hormone interrelationships affecting the selective uptake of 65Zn by the dorso-lateral prostate of the hypophysectomized rat.


An additional purification step for a method for estimating oestriol, oestrone and oestradiol-17 beta in human urine.


Effect of age, sex, gonadectomy, sodium chloride intake, and treatment with cortisol acetate upon the lifespan of adrenalectomized mice of an albino strain.


The effect of progesterone on the development of mouse eggs in vitro.


The effect of cortisol acetate on oestrone-induced mammary gland growth in immature ovariectomized albinomice.


Optinum conditions for the biological assay of gonadotrophins.


Insemination of the guinea-pig by intraperitoneal injection.


Follicle stimulating hormone in the urine of pregnant women.


An examination of new methods for the extraction of human postmenopausal gonadotrophins from urine.


The identity of adrenocortical secretions in lower vertebrates.


The effect of growth hormone on the yield and composition of cows' milk.


The effects of vasopressin on water uptake of the toad, Bufo marinus, while bathed in different hypotonic solutions.


The maintenance of lactation in the rat after hypophysectomy.


Some properties of methylethylstilboestrol.


The influence of chorionic gonadotrophin on the steroid metabolism of sexually retarded men.


The acute effect of adrenal hormones and carbohydrate metabolism upon plasma phosphate and potassium concentrations in man.


A method for the determination of 5 beta-pregnane-3 alpha:17 alpha: 20 alpha-triol in urine.


The effect of oxytocin on mammary gland involution in the rat.


The relationship between urinary oestrogens and oestrogens produced in the body.


Note on the effects of thyroidectomy and thyroid hormone administration on the concentration of bile cholesterol and cholic acid.


The clearance of vasopressin from the splanchnic vascular area and the kidneys.


The effect of oestrone on the mammary gland of adrenalectomized guinea-pigs.


Prevention of vitamin A overdosage by somatotrophic hormone.


The antibacterial activity of hemoglobin. Low concentrations of hemoglobin (0.1 microg./ml. or less) exert a lethal action on some Gram-negative bacteria under certain conditions in vitro. Hemoglobins from various mammals and the distinct genetic types of human hemoglobin all manifest similar bactericidal activity. The bactericidal effect is a function of the globin moiety of the molecule; native and acid or acid-alcohol denatured globins have the same degree of activity. Hemoglobins kill enterobacteriaceae only under precisely controlled conditions. The test medium must be low in ionic concentration and acid in reaction. Various strains of Escherichia and Salmonella are susceptible to the lethal effect of hemoglobin, while the few strains of Shigella, Klebsiella, and Proteus examined were resistant. Certain acid polysaccharides and basic amines or proteins block the bactericidal effect when incorporated in the test in low concentration. Present evidence also suggests that exposure of the microorganisms to certain cations such as magnesium renders them resistant to the lethal action of globin. Hemoglobin loses its bactericidal power when complexed with haptoglobin, and serum fractions rich in free haptoglobin protect otherwise susceptible bacteria from killing by hemoglobin. The reaction appears to be a bactericidal rather than a bacteriostatic one. At 38 degrees C. maximal killing requires approximately 30 minutes; at temperatures of 28 degrees C. or 0 degrees C. the bactericidal action does not take place. The minimal concentration of hemoglobin required to kill 50 per cent of the microorganisms in the test is unrelated to the size of the bacterial inoculum. Under conditions suitable for bactericidal action, hemoglobin is adsorbed onto heat-killed susceptible strains of coliform bacteria; material possessing bactericidal activity can be eluted with dilute mineral acid.


The in vitro action of hydrocortisone on leucocyte migration. Hydrocortisone inhibits the ameboid migration of human leucocytes when added in vitro. The dose-response curve for the reaction between this steroid and leucocytes can be best expressed by a logarithmic plot of the steroid concentrations. Tetrahydrocortisone and desoxycorticosterone had no effect on in vitro leucotyte migration.


Colicine K. II. The preparation and properties of a substance having colicine K activity. By chemical fractionation a substance having colicine K activity has been obtained from the culture medium of E. coli K(235) L(+)O. Colicine K activity was found associated with the O antigen of this microorganism. When the O antigen was dissociated, colicine K activity remained with the protein component of the antigen.


Thyroid function in experimental streptococcal pneumonia in the rat. In order to study the effects of a severe bacterial infection on thyroid function rats were subjected to group A streptococcal pneumonia, and thyroid activity determined by measurement of the rate of discharge of I(131) from the thyroid gland. Decreased thyroid activity of moderate to marked degree was observed in the majority of infected animals. Infected animals ate less than normal animals. Since fasting leads to decreased thyroid function, I(131) release rates were measured in control animals pair-fed with infected animals and in control and infected animals force-fed a normal intake. The reduction in thyroid activity seen in acute infection was found to be partly but not entirely due to the associated voluntary food restriction. Although the adrenal glands of rats dying of pneumonia were very large, the thyroid inhibition occurring during the course of experimental pneumonia was not secondary to increased adrenocortical function since infected, adrenalectomized animals, receiving injections of cortisone, showed thyroid inhibition comparable to that observed in intact infected animals. The possible influence of the level of thyroid activity on resistance was evaluated. In two experiments a total of 80 rats in 3 groups was pretreated with propylthiouracil and injected daily with 3 dosage levels of 7-thyroxine for 3 weeks prior to inoculation. Under these conditions mortality rates in infected animals fell with decreasing levels of thyroid function. However, induced hypothyroidism was found to afford no protective effect in comparison with untreated infected animals.


Studies on the formation of collagen. I. Properties and fractionation of neutral salt extracts of normal guinea pig connective tissue. Some properties of cold neutral salt extracts of fresh guinea pig dermis have been described in terms of viscosity, electrophoresis and sedimentation patterns, partial composition, the collagen content, conditions for extraction of collagen, and the effect of certain enzymes. Viscosity of the extracts depended on the collagen in solution as demonstrated by removal of this protein by precipitation or enzymatic degradation. The intrinsic viscosity of the crude 0.45 M extract, as well as that of the isolated collagen was 14.5, identical with that for collagen dissolved by dilute acid, indicating the same high asymmetry ratio for both. Electrophoresis of the skin extracts revealed a slow moving, high, sharp, poorly diffusing boundary in addition to a pattern superficially resembling that of serum. The ultracentrifuge pattern revealed a slowly sedimenting, hypersharp boundary following a large rapidly diffusing peak. The slow moving boundaries in both patterns were abolished by collagenase or heat precipitation of the collagen fraction. Hyaluronidase had no effect on either pattern. Neutral sulfate, chloride, and phosphate extracted more collagen than did thiocyanate. Very little collagen was extracted at 37 degrees C. as compared with that removed at 3 degrees C. A two stage fractionation procedure employing dilute trichloroacetic acid and ethanol is described for the isolation and purification of soluble collagen from crude extracts.


A comparison of the growth of selected mycobacteria in HeLa, monkey kidney, and human amnion cells in tissue culture. HeLa, monkey kidney, and human amnion cells in tissue cultures were compared as sites for the multiplication of strains of tubercle bacilli or original and reduced pathogenicity, and for several other species of mycobacteria capable of causing disease in humans. The arrangement of the pathogenic species inorder of their growth rates in HeLa cells was Mycobacterium fortuitum, Mycobacterium balnei, and the "yellow bacillus," followed closely by the tubercle bacillus. This order was also correct for these species in monkey kidney and human amnion cells, and is the same as that seen in bacteriological media. The arrangement of the strains of tubercle bacilli in order of their growth rates in all three types of cells was: H37Rv, then R1Rv, and lastly H37Ra, which multiplied about as slowly as BCG. An INH-resistant strain grew about as rapidly as H37Rv. Growth of the pathogenic species occurred at about the same rates in HeLa and monkey kidney cells, but was distinctly slower in human amnion cells, which are less active metabolically. Irradiation of the cells in doses up to 5000 r did not affect the subsequent growth of mycobacteria in them. Preliminary experiments with human leprosy bacilli indicate that they can be introduced into these cells in high numbers and that the bacilli then persist for the life of the cells.


Studies on the formation of collagen. II. The influence of growth rate on neutral salt extracts of guinea pig dermis. The total amount of neutral salt-extractible collagen in the skin of growing, suckling guinea pigs amounted to about 10 per cent of the total collagen of the dennis. This is roughly equivalent to a 1 to 2 day increment in dermal collagen incident to growth. Fourteen days of static weight maintained by limited caloric intake reduced the neutral salt-extractible collagen to very low levels. Following this period, 5 to 7 days of steady weight gain induced by ad lib. feeding was required to produce significant increases in this collagen fraction. Return to control levels occurred within 12 days of continuous growth. The amount of collagen extracted from the dermis of young guinea pigs with cold neutral salt solutions varied directly with growth rate (weight gain) and was greatly diminished after short periods of restricted caloric intake. Two days of fasting diminished the total extracted collagen by one-half. Three consecutive extractions with citrate buffer pH, 3.5, of the residues remaining after exhaustive saline extraction removed 40 per cent more collagen from the skins of actively growing animals than from those of animals fasted for 2 days. However, subsequent extraction of residues with dilute acetic acid equalized the total amount of collagen extracted at acid pH from the two groups. The viscosity of cold neutral extracts was unrelated to the concentrations of non-collagenous proteins and carbohydrates but varied directly with the collagen content.


Studies on the pathogenesis of fever. III. The leucocytic origin of endogenous pyrogen in acute inflammatory exudates. The evolution of an acute inflammatory exudate produced in rabbits by the intraperitoneal injection of saline has been described. Evidence has been presented that polymorphonuclear leucocytes release endogenous pyrogen into the cell-free fluid of the exudate. Leucocytes from such exudates have also been shown to release pyrogen into the surrounding medium during incubation in vitro at 37 degrees C. The results of parallel cytological studies have provided evidence which suggests that the leucocytes give up their pyrogen while functionally intact. These observations add further support to the hypothesis that polymorphonuclear leucocytes play a significant role in the pathogenesis of fever.


Studies on the pathogenesis of fever. IV. The site of action of leucocytic and circulating endogenous pyrogen. By means of a method designed to compare the febrile responses produced by intracarotid and intravenous injections, the endogenous pyrogen, which is contained in leucocytic exudates and is present in the serum of rabbits 2 hours after intravenous injections of typhoid vaccine, has been shown to act directly upon the thermoregulatory centers of the brain. In contrast, the exogenous bacterial pyrogen present in serum obtained 5 minutes after vaccine injections was found to act by a different and less direct mechanism. These observations add strong support to the original hypothesis that endogenous pyrogen, presumably derived from polymorphonuclear leucocytes, is an essential factor in the pathogenesis of endotoxin fever.


Studies on the pathogenesis of fever. V. The relation of circulating endogenous pyrogen to the fever of acute bacterial infections. An endogenous pyrogen, which is indistinguishable from leucocytic pyrogen, has been demonstrated in the blood streams of rabbits with fevers caused by experimental pneumococcal and streptococcal infections. Like the endogenous pyrogen previously detected in the serum of animals with fever produced by the intravenous injection of typhoid vaccine, the newly discovered circulating factor acts directly upon the thermoregulatory centers of the brain. Its origin from polymorphonuclear leucocytes at the site of infection appears to have been established. The possible relationship of this circulating endogenous pyrogen to the pathogenesis of other forms of fever is discussed.


Ratio scales and category scales for a dozen perceptual continua.


Tissue culture studies on bacterial allergy in experimental brucellosis. I. The effect of Brucella suis whole antigen on cultures of spleen from normal and brucella-infected guinea pigs. Tissue culture methods have been used to investigate infectious allergy in experimental brucellosis. A study was made of the effect of whole cell Brucella antigen on cultures of spleen from normal and Brucella-infected guinea pigs. The degree of toxicity was based upon the inhibition of migration of wandering cells and upon the morphologic appearance of stained sections of tissue cultures at different periods of incubation. A suspension of heat-killed Br. suis was more toxic for splenic cells from guinea pigs infected with Br. suis than for normal splenic cells. Macrophages were more sensitive than leucocytes to the toxic action of the antigen. The degenerative changes observed in Brucella-sensitive cells exposed to the antigen were similar to the degeneration previously observed in cultures of tuberculin-sensitive cells in the presence of tuberculin. The specific toxicity of the whole Brucella antigen, however, was more marked than that of tuberculin. Preliminary experiments indicate that serum and plasma containing specific antibodies obtained from Brucella-infected guinea pigs reduce the toxic effect of the antigen in cultures of both normal and Brucella-sensitive cells. The protective action of the homologous antiserum was greater for Brucella-sensitive cells than for normal cells.


Intelligibility as a function of frequency of usage.


The semantic differential and mediated generalization as measures of meaning.


Selective sampling in discrimination learning.


Cutaneous discrimination of radiant heat.


The role of prefeeding in an apparent frustration effect.


Resistance to extinction as a function of the discrimination habit established during fixed-ratio reinforcement.


Effect of amount of interpolated learning and time interval before test on retention in rats.


Judgments of visual velocity as a function of length of observation time.


The restitution of the medulla oblongata following unilateral excision in embryos of the frog.


Classical conditioning of human pupillary dilation.


Observation on grafted somites from early larval stages of Amblystoma.


Growth regulation in Amblystoma eyes transplanted between larvae of different ages.


Experimental modification of gastrulation in the frog.


Interruption of pregnancy in the rabbit by the administration of estrogen.


Sexual photoperiodicity of the cyprinid fish, Notropis bifrenatus (Cope), in relation to the phases of its annual reproductive cycle.


Regeneration and differentiation in buds of Amaroecium treated with nitrogen mustard.


Diuresis and antidiuresis.

Diuresis and antidiuresis.


Diffuse interstitial pulmonary fibrosis: the Hamman-Rich Syndrome.


Labor with emphasis on stage I.

Labor with emphasis on stage I.


Syphilis in Shakespeare's tragedies.

Syphilis in Shakespeare's tragedies.


Preliminary report on treatment of mongoloids.


Nitrogen fixation by new species of Nocardia.


The distribution of lithium in amphibian gastrulae autoradiographically demonstrated.


Office study of the infertility problem.


OSWALD THEODORE AVERY, 1877-1955.

OSWALD THEODORE AVERY, 1877-1955.


Some observations upon the mode of sporulation and relationships of monosporous actinomycetes.


The metabolism of inorganic polyphosphate in mycobacteria.


The presence of the transmissible agent F in non-recombining strains of Escherichia coli.


The isolation and composition of the nucleic acids of Aerobacter aerogenes.


Decarboxylation of neutral amino acids in Proteus vulgaris.


The bulging factor, a fungistatic antibiotic produced by a streptomyces strain, with evidence of an active water-excreting mechanism in fungi.


Optical activity of amino acids formed by reductive amination in Bacillus subtilis.


The effect of spore germination and development on plate counts of fungi in soil.


The mineral nutrition of Rhizopus stolonifer.


Some general properties of a psychrophilic pseudomonad: the effects of temperature on some of these properties and the utilization of glucose by this organism and Pscudomonas aeruginosa.


A method for isolating Streptomyces.

A method for isolating Streptomyces.


Morphogenesis and polymorphism of Ankistrodesmus spp.


The hexose constituents of some Shigella polysaccharide hydrolysates.


The isolation of yeasts from soil.

The isolation of yeasts from soil.


The effect of molybdenum deficiency on the catalase and peroxidase content of Neurospora crassa.


Effects of molybdenum, copper and iron on some enzymes in Neurospora crassa.


Nutritional requirements and biosynthetic capabilities of the parasitic flagellate Strigomonas oncopelti.


The mode of action of phenanthridines: the effect of ethidium bromide on cell division and nucleic acid synthesis.


The uptake of amino acids during the terminl bacteraemia in guinea pigs infected with Bacillus antbracis.


The effect of metabolite analogues on growth of Bacillus anthracis in the guinea pig and on the formation of virulence-determining factors.


Animal strains of group G streptococci and their serological typing.


The inhibitory effect of low temperature on early stages of zygospore production in Rhizopus sexualis.


Renal tubular transport of inorganic divalent ions by the aglomerular marine teleost, Lophius americanus. A characterization was attempted of the mechanisms involved in the tubular transport of inorganic divalent ions by the aglomerular kidney of Lophius, attention being paid particularly to the possible existence of transport maxima (Tm) and to competition for transport among related substances undergoing tubular excretion. Excretory rates of divalent ions in non-treated fish during standard laboratory conditions paralleled spontaneous changes in urine flow. Tm rates of excretion were reached for magnesium, sulfate, and thiosulfate with corresponding plasma levels of 2 to 5, 5 to 17, and 4 to 12 microM/ml. respectively. Elevation of magnesium chloride levels in plasma markedly depressed calcium excretion; sodium thiosulfate similarly depressed sulfate excretion. Experimental observations suggest the existence of a transport system for divalent cations separate from another for divalent anions. Within each transport system the ion with the higher excretion rate depressed competitively transfer of the other ion. Neither system was influenced by probenecid (benemid) in doses which markedly depressed the simultaneous excretion rate of p-aminohippuric acid.


Enzymic dephosphorylation of pepsin and pepsinogen. It has been shown by the work presented in this paper that it is possible to dephosphorylate enzymically pepsin and pepsinogen with a variety of phosphatases. With the aid of a phosphodiesterase and the prostate phosphatase it has been established that the phosphorus in the two proteins is present as a diester and connects two sites of the peptide chain in a cyclic configuration. Removal of the phosphorus does not affect the proteolytic activity against hemoglobin or the synthetic substrate acetyl-L-phenylalanyl diiodotryosine, nor the pepsinogen pepsin transformation. However, an increase of the autodigestion of pepsin is observed.


Transmission in squid giant synapses: the importance of oxygen supply and the effects of drugs. Synaptic transmission was studied in giant synapses of the stellate ganglion of the squid. When bathed in air-saturated sea water, the synapses deteriorate in 10 to 20 min.; if the sea water is saturated with 100 per cent oxygen, they function steadily for up to 12 hours. Optimal results probably require a medium with lower magnesium and higher calcium than the sea water used. Of eighteen compounds known to affect other synapses (Table I), none had stimulatory effects when applied to the preparation, but ten produced synaptic depression in concentrations of 10(-3) gm. per ml. or higher. The only exception was procaine, which blocked at 6 x 10(-5) gm. per ml. Intracellular recording with microelectrodes near the synapse showed that the block was associated with a slower rise of the excitatory post-synaptic potential, without a change in the depolarization required to initiate the spike. Procaine was exceptional in also increasing the depolarization at which the spike occurred.


Photoreactivation in vitro of ultraviolet-inactivated Hemophilus influenzae transforming factor. Hemophilus influenzae-transforming DNA, which has been inactivated by ultra-violet radiation, is reactivated by visible light in the presence of a cell-free extract of Escherichia coli B. The time rate of reactivation is increased by increasing the E. coli extract concentration, the temperature, and the intensity of illumination. Only DNA containing an ultraviolet-damaged genetic marker exhibits increased transforming activity after treatment with the photoreactivating system. The reactivating capacity of the extract remains in the top supernatant after centrifugation at 110,000 x g for 1 hour and is not present in the pellet. This capacity is destroyed by heating to 90 degrees C. for 1 minute. The active system of the E. coli extract is separable into dialyzable, heat-stable and non-dialyzable, heat-labile fractions. The dialyzable fraction contains at least one component which limits the maximum degree of recovery attained.


Simultaneous hydrolyses of esters and proteins at saturation levels. A direct titration method for the determination of proteolytic activity is discussed. This involves the potentiometric measurement of the volume of 0.08 N NaOH required to maintain a constant pH (8.0) during the time of the hydrolysis. It is a sensitive method which presents several advantages; viz., it measures simultaneously protease and esterase activity, it follows the hydrolysis very closely and from the first stages; the titration is continuous and on the same sample. This method determines a constant fraction of the groups titratable by formol titration. The ratio formol: direct titration is represented by a factor "f" which is presumed to be distinct for each protein-enzyme system. Kinetic studies, using this method, revealed that the rates of hydrolysis of mixtures casein-gelatin on one hand, casein-BAEE or gelatin-BAEE on the other, are always larger than those of the corresponding isolated substrates. In many cases the resulting rates are equal or nearly equal to the sum of the individual rates, even though the mentioned rates have been determined within the saturation zones for every substrate. The former observations are inconsistent with the theory of the formation of an intermediary enzyme-substrate compound, unless it is assumed that the enzyme has a specific active group for each substrate.