Fibrinolytic system of guinea pig serum.


Miniature responses under voltage-clamp.


Effects of intracarotid injections of hypertonic solutions on the neurohypophyseal milk-ejection mechanism.


Immediate effects of stretch on muscle contractility.


EEG correlates of osmotic activation of the neurohypophyseal milk-ejection mechanism.


Effect of various psychotomimetic drugs on rate of appearance of carbon-14 in the brains of mice after administration of C14 glucose.


The pH of K-deficient muscle.

The pH of K-deficient muscle.


Relation between spinal level and peripheral location of afferents in calf muscles of the cat.


Temperature and vagal effects.

Temperature and vagal effects.


Increase in weight of the submandibular salivary glands of rats following periodic amputation of the erupted portion of the incisor teeth.


Role of parotid ducts in secretion of hypotonic saliva.


Histamine metabolizing activity of the stomach and intestine of the rat.


Synthesis and secretion of pepsinogen in the rat; effects of alteration of adrenal activity and of body hydration.


Mechanism of gastric hypersecretion following portacaval transposition.


Gastric secretion and parathyroid function in rats.


Effect of vagotomy on secretin and pancreozymin activity of intestines of albino rats.


Mechanical and electrical activity in intestinal smooth muscle.


Effect of tetraiodothyroformic acid on oxygen consumption of the cholesterol-thiouracil-fed rat.


Effect of growth hormone and thyroxine on growth and chemical composition of muscle, bone and other tissues in thyroidectomized-hypophysectomized rats.


Renal clearance of glucose in hypothermic dogs.


Thiocyanate space in growing domestic fowl.


Influence of the adrenal gland on hypothermic response of the rat to chlorpromazine, reserpine and serotonin.


Comparative effects of dietary fatty acids and triglycerides on lymph lipids in the rat.


Lipid composition of Kupffer cells.

Lipid composition of Kupffer cells.


Effect of single and chronic choline supplements on phospholipid metabolism of the dog.


Effect of prolonged cold exposure on oxidative phosphorylation and adenosinetriphosphatase activity of rat liver tissue.


Biochemical response to trauma. IV. Corticosteroid levels in plasma of rats subjected to tumbling trauma.


Effects of prenatal x-irradiation on testicular function and morphology in the rat.


Induction of estrus by electrical stimulation.


Transmembrane potentials in the rat myometrium during pregnancy.


Relationships between contraction and membrane electrical activity in the isolated uterus of the pregnant rat.


Hepatic function of the golden hamster after exposure to cold and during hibernation.


An analysis of the metabolic responses of rats exposed to cold.


Effect of heat and solar radiation on vitamin A utilization by the bovine animal.


Effect of diamox on plasma and urine acid-base composition during chronic respiratory acidosis.


Inactivation of serum ribonuclease by the kidney.


Micropuncture study of the mammalian urinary concentrating mechanism: evidence for the countercurrent hypothesis.


REPORT of World Health Organization Study Group on Schizophrenia-Geneva, September 9-14, 1957.


Influence of variations in blood flow and of dinitrophenol on renal oxygen consumption.


The American melting pot: its meaning to us.


Day hospitals for severely disturbed schizophrenic children.


Teaching the principles of ambulant psychotherapy.


A serious and little-recognized deficit in post-war psychiatric residency training.


The symptomatic relief of anxiety with meprobamate, phenobarbital and placebo.


Psychogenic hypersomnia.

Psychogenic hypersomnia.


The characteristics of thought disturbances as related to electroencephalographic findings in children and adolescents.


Philadelphia metropolitan psychiatry in 1959.


Withdrawal from neuroleptic drugs.

Withdrawal from neuroleptic drugs.


Drugs--single or multiple daily dosage?

Drugs--single or multiple daily dosage?


Serum calcium levels after ECT modified with scoline.


Preliminary observations on trifluoperazine in schizophrenia.


A clinical trial of monosodium glutamate (1-glutavite(R)) on hospitalized elderly male psychotic patients.


Treatment of bladder and bowel incontinence in elderly mental patients with noreth-androlone (nilevar).


Clinical report on methoxypromazine: a new phenothiazine.


Clinical uses of deanol (deaner): a new type of psychotropic drug.


Patient government.

Patient government.


Edward A. Strecker; 1886-1959.

Edward A. Strecker; 1886-1959.


Patients' expectancies and relearning as factors determining improvement in psychotherapy.


Contron of behavior as a crucial factor in intensive psychiatric treatment in an all adolescent ward.


Problems in establishing and maintaining psychiatric units in general hospitals.


The psychiatric emergency clinic: a flexible way of meeting community mental health needs.


Repetition of verbal signals: behavioural and physiological changes.


Permissiveness, its definition, usefulness and application in psychotherapy.


Diagnosis, treatment and results in anorexia nervosa.


Fear, hostility, reality.

Fear, hostility, reality.


Suicide and medical responsibility.

Suicide and medical responsibility.


Marsilid (iproniazid) and electroshock.

Marsilid (iproniazid) and electroshock.


The role of the father in families with a schizophrenic patient.


The social-legal counselling board: an experiment in the interdisciplinary approach involving law, psychiatry, and social work.


Cyloserine as an antidepressant agent.

Cyloserine as an antidepressant agent.


Comparison of proclorperazine and chlorpromazine in hospitalized chronic schizophrenics.


Intensive short-term therapy in a day care facility for control of recurrent psychotic symptoms.


Pre-admission drug treatment of state psychiatric hospital patients.


Druginduced tranquilization vs. drug induced agitation.


Experience with trifluoperazine in 110 female schizophrenics.


Clinical efficacy of proclorperazine (compazine) in mental illness.


Electrocardiography as a routine admission procedure in a large neuropsychiatric hospital: an evaluation.


Pierre M. F. Janet; 1859-1947.

Pierre M. F. Janet; 1859-1947.


California Assembly bill 437: legal insanity.


Edwin Garvin Zabriskie, 1874-1959.

Edwin Garvin Zabriskie, 1874-1959.


The politics of public health.

The politics of public health.


The politics of public health; reactions & summary.


The preparation of state and local health regulations.


Alcoholism in California; the experience of the California State Department of Public Health.


Epidemiological methods in the study of alcoholism.


The epidemiology of Q fever in the United States.


The importance of public education for health on the world scene.


Survivorship in cerebral palsy.

Survivorship in cerebral palsy.


Social work consultation in a prepayment medical care plan.


Should an occupational health program be included in local health department activities.


Industrial hygiene programs in local health departments.


In memoriam: Asa Crawford Chandler (1891-1958).


The worm turned; action and reaction.

The worm turned; action and reaction.


An appraisal of the enterovirus problem.


A study of pigmentation and other changes in the liver in malaria.


Trimeresurus elegans (Gray, 1849), the Sakishima habu, a venomous pit viper from the Ryukyu Islands.


The cockroaches Blaberus craniifer and Blaberus discoidalis as vectors of Salmonella typhosa.


Field observations on the biting habits of Culex tarsalis at Mitchell, Nebraska, and Logan, Utah.


When bubonic plague came to Chinatown.

When bubonic plague came to Chinatown.


Observations on treatment of infant diarrhea in Panama.


The serological diagnosis of eosinophilic lung (tropical eosinophilia) and its etiological implications.


Observations on Anopheles (Kertezia) bellator D. & K. in British Guiana.


On the cultivation of Trypanosoma brucei in vitro.


Antibodies to yellow fever and other arthropod-borne viruses in human residents of San Vicente de Chucuri, Santander, Colombia.


Further studies on the experimental transmission of yellow fever by Sabethes chloropterus.


Species crossing in Oncomelania.

Species crossing in Oncomelania.


Malaria in oases of Eastern Saudi Arabia.


The challenge.

The challenge.


Cancer of the lower left colon and rectum: current status.


Chemotherapy in chronic urinary tract infections.


Central nervous system reactions to small doses of tranquilizers; report of one death.


Topical use of methyl prednisolone in various dermatoses.


Screening patients for ataractic therapy: use of a hyperventilation test.


Osteoporosis: the Otto-Chrobak pelvis.

Osteoporosis: the Otto-Chrobak pelvis.


Prochlorperazine: a clinical evaluation.


Resection of left lobe of the liver for hepatoma; case report.


Nutritional supplementation enhanced by D-sorbitol.


An instrument for intravenous insertion of polyethylene tubing without cut-down.


Guillain-Barre syndrome in a pregnant woman.


Studies in psychic fatigue. II. Physiological effects of D-amphetamine.


The differential diagnosis of jaundice with special reference to its surgical treatment.


Carcinomas of the appendix.

Carcinomas of the appendix.


Traumatic rupture of the spleen associated with portal cirrhosis, portal hypertension, and congestive splenomegaly.


Ectopic breast tissue: report of unusual case.


Successful cardiac resuscitation in the recovery room.


The carcinoid neoplasm and syndrome: a review with extension by unusual cases.


Stainless steel mesh replacement of anterior abdominal wall; radical excision of recurrent desmoid tumor.


A comparison of the efficacy of antibiotics in open and closed loop strangulation obstruction.


Tracheostomy for respiratory muscle failure in infants and children.


Spontaneous esophageal cutaneous fistula.


Localized arteritis and thrombosis of the iliac artery associated with the use of inguinal truss.


Adenomatous polyp of the duodenum: report of two cases.


Spontaneous rupture of renal neoplasms: review and report of a case of ruptured renal cell carcinoma.


Supracondyloid process.

Supracondyloid process.


Use of five per cent dextrose in water with citrated blood.


Reflux esophagitis: modalities in surgical therapy: subtotal gastrectomy: right colon interposition.


A further evaluation of lymphedema of the arm following radical mastectomy and postoperative x-ray therapy.


Spontaneous hemopneumothorax.

Spontaneous hemopneumothorax.


Nonparasitic hepatocystic disease: a report of nine cases.


Evisceration of abdominal wounds: factors influencing incidence and prevention.


Hyperparathyroidism and chronic calcific pancreatitis.


A simplified extracorporeal pump oxygenating system.


Direct approaches for the treatment of aortic insufficiency.


Electrical burns of the lips: a modified plan of treatment.


The relationship of trauma to arthritis.


Some chemical aspects of inflammation.

Some chemical aspects of inflammation.


Regeneration of urinary bladder after subtotal resection for carcinoma.


Carcinoma rising in the gastric stump following gastric resection for benign ulceration.


Surgical implications of mediastinal granulomas.


Chloroform in modern anaesthesia.

Chloroform in modern anaesthesia.


John Snow, M. D.; 1813-1858.

John Snow, M. D.; 1813-1858.


Halothane; oxygen anaesthesia for bronchoscopy: a method suitable for children.


Muscle relaxation with decamethonium (C10).


A clinical trial of dihydro-hydroxycodeinone pectinate.


Hydroxydione.

Hydroxydione.


Collapse after halothane: case reports.

Collapse after halothane: case reports.


Post-operative axillary artery thrombosis: an unusual complication.


Lingual thyroid; complicating general anaesthesia.


Severe head injuries.

Severe head injuries.


The duration of action of levallorphan.

The duration of action of levallorphan.


Nitrous oxide, hypoxia and the anaesthetic state.


A sonic analyser for anaesthetic vapours.


Orotracheal connection with minimal resistance. III.


Dr. Zebulon Mennell.

Dr. Zebulon Mennell.


Dr. John Gillies.

Dr. John Gillies.


Dr. I. W. Magill.

Dr. I. W. Magill.


Dr. R. J. Minnitt.

Dr. R. J. Minnitt.


[Chagas' disease: present status in Peru].


A study of the transverse cervical and dorsal scapular arteries.


Renewal of chief cells and goblet cells in the small intestine as shown by radioautography after injection of thymidine-H3 into mice.


The origin and course of the cardioaccelerator fibers in the dog.


Accessory adrenal cortical nodules in the mouse.


Induction of portions of the chick lens without contact with the optic cup.


Effects of delayed fertilization on the development of pronucleus and the segmentation of hamster ova.


Observations on the morphogenesis and histochemistry of the bovine preattachment placenta between 16 and 33 days of gestation.


On the lymphatic system of Ascaphus; its evolutionary significance.


Lateral arterial anastomosis: a point of technique.


Aorto-intestinal fistula following aortic homotransplantation.


Thromboangiitis obliterans affecting women; report of a case and review of the literature.


Polythene fabric as an arterial prosthesis.


Reflex sympathetic dystrophy: treatment of syncardial compression.


Some basic dificiencies of the plethysmographic method and possibilities of avoiding them.


A clinical evaluation of quinidine polygalacturonate.


Long term therapy of coronary arteriosclerosis.


The Schanz osteotomy for irreducible dislocation of the hip; a clinical study with an evaluation of results based on the follow-up of 100 cases.


Professor Sakari Mustakallio: 60 years.

Professor Sakari Mustakallio: 60 years.


Filtration of 3 millimetre Al in cholecystography: with special reference to the scattered radiation reaching the gonadal area.


Pleuropulmonary x-ray findings in systemic lupus erythematosus and rheumatoid arthritis.


The value of mictiocysto-urethrography in pediatric urological diagnosis.


Treatment of metastatic thyroid carcinoma with radioiodine.


Thyroid function in cases of mammary cancer: observations with special reference to the effect of hypophysectomy.


Roentgenologically demonstrable changes in the synchondroses of the pelvis during pregnancy.


Reduction of the radiation doses to the gonads in x-ray diagnosis.


Blood pyruvic acid concentration in carcinoma during radiotherapy: with especial consideration of the effect of cocarboxylase and thiamine monophosphate.


Prevention of cancerous diseases in Finland.


Absence of the septum pallucidum in pneumoencephalograms: report of a case.


Pressure recordings with an obstructive double catheter in urological roentgen examinations: a preliminary report.


Four cases of osteopoikilosis.

Four cases of osteopoikilosis.


Radiotherapy of inoperable cancer of the breast.


Roentgen therapy of intrathoracic metastases from carcinoma of the breast.


Left-sided gall-bladder without situs inversus: two roentgenologically diagnosed cases.


Perforations of the renal pelvis or ureter observed at retrograde pyelography.


Changes produced by age in the arterial circulation of the pelvis and the lower extremities.


The roentgen standard of the Institute of Radiophysics.


The vaginal smear method in the hormonal treatment of patients with metastatic breast cancer.


Gastroduodenal signs of irritation and ulcers.


Fully electronic exposure timer for x-ray apparatus.


Orthoradial jaw pantomography.

Orthoradial jaw pantomography.


Primary carcinoma of the lung: results of surgical treatment.


Radiations doses to the radiologist teacher and his pupil during fluoroscopic roentgen examinations.


Pneumonia in adults during the influenza epidemic of 1957: roentgenological observations.


The uptake of radioactive phosphorus in the diagnosis of malignant tumours.


Post-mortem observations on clinical tumor diagnoses.


Short oesophagus and stricture of the cardia due to sliding hernia and hiatal insufficiency.


Alterations caused by intrasplenic injections of x-ray contrast media: observations on rats.


On the prognosis of Hodgkin's disease: a clinical and pathological study of 120 cases.


Off-focus radiation: its significance to the roentgenographic results when a narrow beam of rays is used in roentgenography.


Radiological appearance of cholesterosis of the gall bladder.


The diagnostic value of bronchography and bronchoscopy in bronchial cancer.


[Effect of conditioning on synkinetic activity of children studied as a function of anatomic laterality].


On the development of coagulation factors in early neonatal life.


The amounts of the blood clotting factors VIII & IX in umbilical venous blood.


The determination of factors in fibrinolysis in umbilical venous blood.


Testing association of metric traits and marker genes.


Microcephaly in the Netherlands: a clinical and genetical study.


Enzymic evidence of a galactosemic trait in parents of galactosemic children.


Muscular dystrophy in childhood; the genetic aspect; a field study in the Leeds region of clinical types and their inheritance.


Distribution of birth weights of Chinese and Indian infants born in Singapore: birth weight as an index of maturity.


The frequency of twinning in poor Chinese in the Maternity Hospital Singapore.


The frequencies of haptoglobin types in five populations.


Preconceptions about vaccination against paralytic poliomyelitis.


Practical aspects of psychotherapy.

Practical aspects of psychotherapy.


Digitalis intoxication: a clinical report of 148 cases.


Epidemiologic and clinical observations in sarcoidosis.


Corticotropin (ACTH) and the adrenal steroids in the management of ulcerative colitis: observations in 240 patients.


Disability following gastric surgery for benign disease, as observed by the internist.


Acute nonobstructive pyelonephritis: occurrence of bacteriuria after apparent recovery.


Radioactive phosphorus in the treatment of chronic leukemias: long-term results over a period of 15 years.


Polycythemia and hydronephrosis or renal tumors.


Observations on some possible precursors of essential hypertension and coronary artery disease. VI. Comparison of the circulatory reactivity to the cold pressor test and to the smoking test.


The role of surgery in the management of unilateral pleural effusion.


Trauma and rheumatism.

Trauma and rheumatism.


Waldenström's macroglobulinemia: clinical pathological conference at the National Institutes of health.


Remission in disseminated coccidiodomycosis produced by amphotericin B.


Idiopathic cardiac hypertrophy with endomyocardial fibrosis: report of a case developing after recovery from a purulent lung abscess.


An unusual case of Salmonella choleraesuis meningitis: cure following surgical excision of an infected subarachnoid cyst.


Renal calculi as complications of leukemia and lymphomata.


The use of chelating agents in the treatment of acute porphyria.


Coxsackie viruses as a cause of disease in man.


Studies on the effect of oral antidiabetic compounds on glucose tolerance, on islet cell structure, and on the in vitro metabolism of isolated muscle.


General pharmacodynamics of the hypoglycemic arylsulfonamides.


The pharmacology of chlorpropamide.

The pharmacology of chlorpropamide.


Hypoglycemic sulfonylureas: effect of structure on activity.


The physical properties of chlorpropamide and its determination in human serum.


Metabolic fate of chlorpropamide in man.


Relative potencies of chlorpropamide and tolbutamide in man.


Effects of administration of chlorpropamide upon the carbohydrate metabolism of isolated tissues.


In vivo effect of insulin and chlorpropamide on certain liver enzymes in rats.


Some effects of tolbutamide and chlorpropamide in vitro.


Inhibition of the diabetogenic action of somatotropin by tolbutamide.


Degradation of insulin-I 131 and glucagon-I 131 and factors influencing it.


Determination of the rate of insulin destruction in vivo.


A comparison of the influence of tolbutamide and small doses of insulin on the splanchnic output and peripheral uptake of glucose in man.


The relationship between the mechanism of action of the sulfonylureas and the secretion of insulin into the portal circulation.


Changes induced by insulin and tolbutamide in the glucose output of the liver.


Effect of chlorpropamide on intermediary metabolism in human subjects.


Comparison of some metabolic effects of insulin, chlorpropamide, and other hypoglycemic substances.


Metabolic effects of continued administration of sulfonylurea derivatives in selected diabetic subjects: interrelations with glucagon.


Metabolic studies of chlorpropamide in normal men and in diabetic subjects.


A comparison of the acute hypoglycemic potencies of tolbutamide and chlorpropamide.


Studies with chlorpropamide in diabetic patients.


Use of chlorpropamide in diabetes mellitus in usual diabetic patients and in primary and secondary tolbutamide failures.


A laboratory and clinical study of chlorpropamide in ambulatory diabetics.


Clinical experience with chlorpropamide.


The role of a tolbutamide tolerance test in the detection of the mild diabetic state: a preliminary report.


Experiences with tolbutamide and chlorpropamide in tuberculous diabetic patients.


The intravenous tolbutamide response test in the diagnosis of mild diabetes.


A clinical comparison of chlorpropamide and tolbutamide.


Experiences with chlorpropamide with reference to its intermittent use.


A clinical and pharmacological comparison of chlorpropamide and other sulfonylureas.


One year of clinical experience with chlorpropamide in more than one hundred diabetic patients.


The correlation between oral dosage, blood levels, and clinical and metabolic activity of chlorpropamide in the treatment of diabetes mellitus.


Clinical experiences with chlorpropamide, with special reference to comparison with previous experience with carbutamide and tolbutamide.


Clinical experiences with chlorpropamide given to hospitalized patients.


Observations on the mode of action and clinical effects of chlorpropamide in diabetes mellitus.


Clinical experiences with chlorpropamide: a double-blind study.


Long-term therapy with chlorpropamide.

Long-term therapy with chlorpropamide.


Clinical evaluation of chlorpropamide in diabetes mellitus.


Blood levels of chlorpropamide in normal men following chronic administration.


Sulfonylurea drugs in the treatment of diabetes mellitus.


Clinical study of the effects of chlorpropamide on normal subjects and on diabetics.


Preliminary clinical and experimental studies with chlorpropamide in diabetes mellitus.


The effect of chlorpropamide on alloxan diabetes in mice.


The effects of tolbutamide and chlorpropamide on patients exhibiting jaundice as a result of previous chlorpropamide therapy.


Studies on the use of chlorpropamide in patients with diabetes mellitus.


Clinical experience with chlorpropamide in the management of diabetes mellitus.


Clinical and experimental studies with chlorpropamide in diabetes mellitus, in normal individuals, and in nondiabetics with hepatic disease.


Experiences with chlorpropamide, especially in the brittle diabetic.


A preliminary metabolic and clinical evaluation of chlorpropamide.


Chlorpropamide: a new sulfonylurea studied in the treatment of thirty diabetic patients.


Preliminary report on the treatment of diabetes mellitus with chlorpropamide.


Considerations for control norms to evaluate results of treatment in diabetes mellitus.


The clinical results of the treatment of diabetes mellitus with chlorpropamide.


Tolerance for alcohol in patients on chlorpropamide.


The treatment of diabetes mellitus in areas of nutritional deficiency.


The problem of diabetes in the Singapore population and the impact of oral antidiabetics on its management.


Clinical studies with chlorpropamide.

Clinical studies with chlorpropamide.


Clinicotherapeutic evaluation of chlorpropamide, a new sulfonylurea derivative for the treatment of diabetes mellitus.


The use of chlorpropamide in brittle and poorly controlled diabetes mellitus.


Chlorpropamide in the management of the adult diabetic patient.


Advantages and disadvantages in shifting patients from tolbutamide to chlorpropamide.


Comparative hypoglycemic effects of chlorpropamide, tolbutamide, and furfurylurea.


Chlorpropamide in single dosage and the responses to insulin or glucose in diabetics: the absence of evidence of increased glucose utilization.


Cortisone enhancement of peripheral utilization of glucose and the effects of chlorpropamide.


Influence of chlorpropamide upon post-pancreatectomy and spontaneous diabetes.


The effects of chlorpropamide on endocrine function in patients with diabetes mellitus and its effects in other endocrine disorders.


Clinical experience in the use of chlorpropamide in the treatment of diabetes mellitus.


Chlorpropamide and diabetes mellitus: summary of the monograph.


Hypophysectomy in the treatment of breast cancer.


A note on the semimembranosus muscle.

A note on the semimembranosus muscle.


On the nature and treatment of wound shock.


The centenary of of the re-interment of John Hunter.


Sommé's manuscript report on a case of fungoid disease of the gums and upper jaw (Madame de Harven), with copies of consultations by Roux, Boyer and Dupuytren.


Cancer cells in the blood; a five to nine year follow up study.


The efficacy of chloromycetin in the treatment of strangulation obstruction.


Disseminated intravascular coagulation: a cause of shock.


Experience with gastric resection by the Péan-Rydygier-Billroth I method.


Vagus section in the treatment of gastrojejunal ulcer; a reappraisal after long term follow up.


The anatomy of Kerckring's valves; case report on their maldevelopment.


Surgical experience with the lower esophageal ring.


Transabdominal repair of esophageal hiatus hernia.


Bile duct repair: an aid to the identification of the hilar structures.


Bacteriologic studies and pressure recordings in jejunal Roux-en-Y segments used to shunt spinal fluid in hydrocephalic dogs.


Supravalvular stenosis of the aorta.

Supravalvular stenosis of the aorta.


Iron metabolism in patients after partial gastrectomy.


Spontaneous perforation of the stomach in the newborn; analysis of thirteen cases.


The value of digital plethysmography in evaluating patients with peripheral arteriosclerosis for lumbar sympathectomy.


Respiratory arrest following intraperitoneal use of neomycin.


Replacement of vital veins; a comparative, experimental study.


Perfusion of the canine esophagus with secretions of the upper gastro-intestinal tract.


The first case report of an echinococcus liver cyst infected with Salmonella saint Paul.


Coronary arteriovenous fistula: a clinical and physiologic report of a successfully operated case.


Pancreatic cyst in the newborn; a case report.


Congenital tracheo-esophageal fistula in an adult.


Two cases of perforated peptic ulcer occurring as postoperative complications of esophagectomy with jejunal interposition.


Arteriovenous fistula of the splenic vessels; report of a case following splenectomy.


Pneumatosis cystoides intestinalis and regional enteritis.


Chronic intussusception with spontaneous separation of necrotic colon.


The impact of the American Board of Surgery upon surgical education in the United States.


Subarachnoid block anesthesia; a twenty-nine year experience.


Experiences with isolation-perfusion technics in the treatment of cancer.


Massive liver resection for control of severe vasomotor reactions secondary to malignant carcinoid.


Technic of hepatic lobectomy.

Technic of hepatic lobectomy.


Problems in extracorporeal circulation relating to venous cannulation and drainage.


Repair of operative injury to the aortic valve.


Problems in surgery of occlusive disease of the aorta and iliac arteries.


The pattern of arteriosclerotic narrowing of the celiac and superior mesenteric arteries.


Surgical considerations of occlusive disease of innominate, carotid, subclavian, and vertebral arteries.


Surgical treatment of occlusive disease of the carotid artery.


Surgical management in hemophilia and the hemophilioid diseases.


Studies on so-called postgastrectomy pancreatitis.


Planned cholecystostomy.

Planned cholecystostomy.


Carcinoma of the larger bile ducts exclusive of the papilla of Vater; report of five personal cases.


Stenosis of the sphincter of Oddi; transduodenal sphincterotomy and some other surgical aspects.


Strictures of the common bile duct; five to 25-year follow up of 217 operations.


A comparative study of phenmetrazine and dextro-amphetamine in a short-term reducing program in medical students.


Therapeutic use of triamcinolone (kenacort), especially in toxicodendron dermatitis and chronic bronchial asthma.


A clinical comparison of the side effects of tetracycline-nystatin and tetracycline.


The treatment of symptomatic amebiasis with puromycin.


An epidemiological study of the implantation of bacteria in the respiratory tracts of patients with bulbospinal poliomyelitis.


Body fluid concentrations of penicillin following intramuscular injection of single doses of benzathine penicillin G and/or procaine penicillin G.


Sixth Annual Symposium on Antibiotics: opening remarks.


The first thirty years.

The first thirty years.


Penicillin in perspective.

Penicillin in perspective.


The impact of antibiotics on American medicine.


A new long-acting antibacterial sulfonamide, 2,4-dimethoxy-6-sulfanilamido-1,3-diazine: a comparative study.


The history of the broad-spectrum antibiotics.


Antibiotics of Actinomycetes, an introduction and an outlook.


Preliminary report of clinical experience with sulfadimethoxine, a new long-acting sulfonamide.


Sulfadimethoxine, a new long-acting sulfonamide; some preliminary clinical and laboratory observations in infants and children.


Blood and cerebrospinal fluid levels of sulfamethoxypyridazine after intravenous administration in children.


Vasomotor effects produced by the prolonged oral administration of antimicrobial agents in primary hypertension, with special reference to the nitrofurans.


The action of a new steroid acid amide of diaminodiphenyl sulfone on the PR8 strain of influenza virus A in the chick embryo.


Furmethonol; a new antibacterial nitrofuran.


Treatment of amebiasis: toxicity to macaques of the suppressive drug dichlorosalicylanilide.


Observations on the prophylaxis of ophthalmia neonatorum in a Municipal Hospital.


All-purpose penicillin in the treatment of gonorrhea: increasing failure rates with repository penicillins.


Glucosamine treatment of Schistosoma mansoni.


Comparison of toleration and absorption of phenyl p-aminosalicylate with several p-aminosalicylic acid preparations.


Chemoprophylaxis of poliomyelitis in mice through the administration of plant extracts.


Local application of triclobisonium chloride in the treatment of pyogenic dermatoses.


Clinical appraisal of a new topical quaternary compound, Ro 5-0810/I.


Blood levels after oral administration of penicillin V acid or penicillin V salt in relation to gastric acidity.


Benzathine penicillin G in oil; a clinical evaluation in the treatment of early syphilis.


Comparative investigations with acid penicillin V and a water-soluble penicillin V salt under different conditions.


Combined gamma globulin and chloramphenicol therapy of lymphogranuloma venereum.


Studies on oral utilization of penicillin V.


Control of the common cold by autogenous vaccine or by antibiotics.


Investigation of a deposit effect produced by phenoxymethyl penicillin (acid penicillin V).


Chemoprophylaxis in Asian influenza for patients with chronic pulmonary disease.


Spiramycin in the treatment of hospitalized patients and in male patients with acute gonorrheal urethritis.


Experience with spiramycin, a new antibiotic in ophthalmic infections.


The use of spiramycin for acute gonococcal urethritis in men.


The ocular penetration and tolerance of a new antibiotic: spiramycin.


Glucosamine-potentiated tetracycline in the prophylaxis and therapy of surgical infections.


The effect of antibiotics of the tetracycline group on enzymes and the practical clinical significance thereof.


The effectiveness of glucosamine-potentiated tetracycline in upper respiratory infections in children.


Apparent paradox of antimicrobial activity of spiramycin.


The effect of triamcinolone prednisolone, and hydrocortisone on dosage, requirements of tetracycline for control of a Streptococcus infection in mice.


Polyphloretin phosphate complexes of tetracycline and related compounds.


Laboratory and clinical studies with a new, preconstituted, intramuscular solution of oxytetracycline.


Oxytetracycline in urinary tract infections.


Topical use of antibiotics in the treatment of chronic skin ulcers.


Extended low-level dosage of oxytetracycline. II. Progress report.


Insoluble oxytetracycline in the treatment of brucellosis.


Observations on the distribution of C14 oxytetracycline in man.


Triacetyloleandomycin: its use in the treatment of acne and pyodermas caused by resistant Staphylococcus aureus.


Antibiotic therapy of acute gonococcal infections; a study of the comparative efficacy of triacetyloleandomycin, erythromycin, and penicillin V in the treatment of acute gonococcal urethritis.


Antibiotic management of acute infections in the obstetric patient.


Clinical and laboratory evaluation of triacetylolendomycin in a variety of pyogenic infections.


The use of triacetyloleandomycin in chronic infectious asthma.


Triacetyloleandomycin: biochemical correlations.


An evaluation of tetracycline-oleandomycin in the treatment of epidemic typhus.


Further clinical studies with a combination of tetracycline and oleandomycin in the treatment of various infections.


The use of tetracycline-oleandomycin in buccal surgery.


The combination of tetracycline-oleandomycin in pleuropulmonary surgery; preliminary report.


Tetracycline-oleandomycin in the treatment of certain infections encountered in the tropics; with particular reference to the use of combined antibiotic therapy of amebiasis, yaws, lymphogranuloma venereum, tropical ulcer, and acute gonococcal urethritis.


Actual therapeutic approach to the treatment of osteomyelitis.


Combination tetracycline-oleandomycin treatment of acute respiratory infection in childhood.


Triacetyloleandomycin in the therapy of pediatric infections.


The treatment of lymphogranuloma venereum with triacetyloleandomycin.


Antibiotic and resistance studies with leucomycin.


The activity of phenacridane chloride against a number of antibiotic-resistant staphylococci.


Genitourinary infections treated with the antibiotic combination tetracycline-oleandomycin.


In vitro studies with leucomycin.

In vitro studies with leucomycin.


Esters of erythromycin. III. Esters of low molecular weight aliphatic acids.


Laboratory and clinical studies with erythromycin propionate.


Pharmacology and toxicology of erythromycin propionate.


Novobiocin in the treatment of surgical infections.


Sensitivity of Micrococcus pyogenes from burned patients to oleandomycin and oleandomycin-tetracycline combined; emergence of resistance to these antibiotics.


Laboratory and clinical studies of intramuscular erythromycin.


Clinical and laboratory studies of erythromycin propionate.


A comparison of the in vitro to in vivo activity of ristocetin, penicillin, and erythromycin.


Absorption of erythromycin propionate and triacetyloleandomycin.


Comparative studies of oleandomycin, triacetyloleandomycin, and erythromycin, with a brief review of the literature concerning oleandomycin.


A clinical evaluation of triacetyloleandomycin in the treatment of infections due to gram-positive cocci; a preliminary report.


Ristocetin serum levels in children.

Ristocetin serum levels in children.


Correlation of sensitivity patterns of antimicrobial agents by the disc plate method; a preliminary study involving 5600 gram-positive cocci.


Ristocetin in the cerebrospinal fluid during staphylococcal meningitis.


Novobiocin in staphylococcal infections.


Ristocetin in the treatment of seven selected difficult cases.


Treatment of pulmonary abscesses and chronic pulmonary suppurations with oxytetracycline.


Ristocetin in adults and children.

Ristocetin in adults and children.


Experience with ristocetin in staphylococcal pneumonia; observations in 24 patients.


Clinical observations on ristocetin; a preliminary report of its efficacy and toxicity in 20 unselected severe respiratory infections.


Use of ristocetin (spontin) in staphylococcal infections.


Effect of a new hormone, triamcinolone, when combined with the standard treatment of tuberculosis.


Pyridoxine and its relation to cycloserine neurotoxicity; a pharmacological and clinical study.


Actinobolin, a new broad-spectrum antibiotic; origin and biological evaluation.


Isolation of a new antibiotic related to aburamycin.


Production of oncostatic principles in vivo and in vitro by species of the genus Calvatia.


Actinobolin, a new broad-spectrum antibiotic; isolation and characterization.


The effects of actinobolin on the growth of human tumors H.S. No. 1 and H. Ep. No. 3 in the rat.


The effects of actinobolin on human epidermoid carcinoma (H.Ep.No.3) growing in the conditioned Swiss mouse.


Actinobolin, a new broad-spectrum antibiotic; pilot plant studies.


The effect of actinobolin on a spectrum of tumors.


The effects of actinobolin on transplanted mouse leukemias.


Clinical trials of mitomycin C, a new antitumor antibiotic; preliminary report of results obtained in 82 consecutive cases in the field of general surgery.


Isolation, purification, and properties of streptovitacins A and B.


Experimental evaluation of a new antitumor agent, streptovitacin A.


Studies on the carcinolytic activity of fumagillin and some of its derivatives.


Paper chromatography and microbiological assay of the streptovitacins.


Structure studies on streptovitacins A and B.


Biological studies on streptovitacin A, a new antitumor agent.


Origin of a new antitumor agent, streptovitacin.


Present status of vancomycin therapy of staphylococcal and streptococcal infections.


A critical clinical evaluation of kanamycin in severe infections.


The clinical evaluation of vancomycin in treatment of multi-antibiotic refractory staphylococcal infections.


Evaluation of kanamycin in the local treatment of pyodermias.


Clinical evaluation of kanamycin.

Clinical evaluation of kanamycin.


Amphotericin B: intravenous use in 21 patients with systemic fungal diseases.


Sensitivity to the tetracyclines.

Sensitivity to the tetracyclines.


Bacitracin-neomycin detergent spray: effectiveness in the treatment of massive experimental wounds.


The in vitro inhibition of staphylococcal penicillinase by various compounds of chemotherapeutic potential.


The combined use of gamma globulin and broad-spectrum antibiotics in the treatment of osteomyelitis; a preliminary study.


Kanamycin in staphylococcal and other infections of infancy and childhood.


Studies on the epidemiology of strains of Candida in hospital wards.


The effect of long-term antibiotic therapy in patients with cystic fibrosis of the pancreas.


Kanamycin in genitourinary infections.

Kanamycin in genitourinary infections.


Kanamycin: its cerebrospinal fluid diffusion, renal clearance, and comparison with streptomycin.


Use of amphotericin to eliminate Candida from the stools of infants treated with tetracycline.


Kanamycin in pulmonary tuberculosis.

Kanamycin in pulmonary tuberculosis.


A limited study on the use of kanamycin in patients with fibrocystic diseases of the pancreas.


The ototoxicity of kanamycin in man.

The ototoxicity of kanamycin in man.


Treatment of the typhoid carrier state with kanamycin; a preliminary report.


A comparative study of the antibacterial spectra of eleven antibiotics, using three in vitro susceptibility tests.


Treatment of chronic amebiasis, brucellosis, and other infections with kanamycin.


Correlation between results of the tube dilution method for determining bacterial sensitivity to antibiotics and the results of the administration of these antibiotics to patients with staphylococcic bacteremia.


The effect of furazolidone alone and in combination with neomycin on the aerobic intestinal microflora of man.


Renal clearance of kanamycin in children.


The current status of kanamycin therapy.


Kanamycin used alone and in combination with erythromycin for intestinal antisepsis.


Preoperative sterilization of the colon: comparison of various antibacterial agents. IV.


Pseudomembranous enterocolitis, a growing menace an autopsy study.


Studies on the mechanism of action of kanamycin.


A modified two-point turbidimetric assay for kanamycin.


Observations on the treatment of acute gonococcal urethritis in the male with intramuscular kanamycin; a preliminary report.


A resin chromatographic analysis for kanamycin mixtures.


The performance under standardized conditions of antibiotic sensitivity tests using discs that meet official Canadian standards.


The clinical use of kanamycin in staphylococcal infections.


An evaluation of different types of paper concerning their suitability for sensitivity discs.


The international situation with regard to the use of discs for antibiotic sensitivity tests.


Antibiotic concentrations in discs used for susceptibility testing of staphylococci.


Kanamycin in pediatric infections.

Kanamycin in pediatric infections.


Antibiotic sensitivity using pretreated plates. II. A demonstration of inhibitory activity with a low level combination of a sulfonamide and polymyxin B against Proteus species.


Slide microculture in bacteriological diagnosis and antibiotic screening.


Antibiotic bactericidal studies, I. Effect of methods on apparent bactericidal concentrations.


Qualitative and quantitative bacteriological data: a reliable guide to the selection of candidates for, and response to, antibiotic therapy in urinary tract infections.


On the design of antibiotic blood level experiments.


Studies on synergists for antimicrobial agents.


The growth rates and adaptive enzyme activities of chloramphenicol- and oxytetracycline-resistant Escherichia coli.


The influence of combinations of ristocetin and neomycin on intestinal aerobic microflora.


Numerical designation of staphylococcal antibiograms.


Visual detection of antibiotics in milk by means of a dye.


Factors affecting the loss of antibiotic activity in milk.


An evaluation of nystatin and candicidin against a standardized systemic Candida albicans infection in mice.


Comparative effectiveness of antibiotic dusting powders in candidal and non-candidal diaper rashes.


The development of strains of Candida albicans and Coccidioides immitis, which are resistant to amphotericin B.


Enhancement of bacitracin by the metallic ions of group II B.


Antibiotics against plant disease. VI. An agar-diffusion method for determining the effects of chemicals on germination of bean-rust uredospores.


Low-level, long-term feeding of chlortetracycline and the emergence of antibiotic-resistant enteric bacteria.


Nystatin in the control of fungal infections of orchids.


Occurrence, phage-type, and antibiotic susceptibility of staphylococci in various community groups.


Suppression of growth of fungal microflora in the conservation of meat by chlortetracycline.


One year's experience of the Staphylococcus Reference Laboratory, Batavia, New York.


A study of possible in vitro oleandomycin resistance increase in Staphylococcus aureus; a preliminary report.


Intraperitoneal kanamycin; comparison with other antibiotics administered intraperitoneally.


Cause, prevention, and treatment of staphylococcal infections in the hospital.


Staphylococcal carrier studies. I. Characteristics of strains from hospital personnel.


In vitro response of clinical isolates at Cook County Hospital to antimicrobial drugs: a one-year survey.


The spread of staphylococci to the environment.


Selective enrichment medium for paratyphoid bacteria; inhibitory and growth promoting factors.


Reactivation of chlorine-inactivated Escherichia coli.


Effect of growth conditions on chlorine sensitivity of Escherichia coli.


Production of fumaric acid by Rhizopus arrhizus.


Production of flavor in cured meat by a bacterium.


Studies of the growth-promoting effect of antibiotics in chicks on a purified diet.


Therapy of psittacosis-infected parrots with chlortetracycline.


Preservation of microbiological assay organisms by direct freezing.


Sporulation by some strains of nocardiae and streptomycetes.


Antibiotic therapy of clostridial myonecrosis in irradiated mice.


Microbiological production of carotenoids. IV. Effect of various grains on production of beta-carotene by mated strains of Blakeslea trispora.


The incidence of Candida albicans in poultry; evaluation of nystatin and chlorhydroxyquinoline in the prevention of experimental moniliasis.


Microbiological production of carotenoids. V. Effect of lipids and related substances on production of beta-carotene.


Calibration of laboratory aeration apparatus.


Location of an esterase in Aspergillus niger.


The distribution of reticulo-endothelial elements in the intestinal mucosa and submucosa of germ-free, monocontaminated and conventional chickens orally treated with penicillin.


Bacterial deterioration of emulsion oils. I. Relationship between aerobes and sulfate-reducing bacteria in deterioration.


Causation, prevention, and control of staphylococcal disease in hospitals; panel discussion.


The current status of erythromycin, kanamycin, novobiocin, oleandomycin, ristocetin, and vancomycin, with particular reference to their use in staphylococcal disease; panel discussion.


Polymerized organic salts of sulfonic acids used as dispersing agents in microbiology.


A new technique for the use of sodium azide (hydrazoic acid) as an inhibitive agent.


Screening for antibiotics active against intracellular bacteria.


The effect of gamma globulin on antibiotic requirements for control of standardized infections in mice.


The influence of submaximal antibiotic levels on the growth of chlortetracycline-resistant bacteria.


Palatability of broad-spectrum antibiotics for swine.


Bacterial deterioration of emulsion oils. II. Nature of the relationship between aerobes and sulfate-reducing bacteria.


Studies on monocontaminated chickens (Clostridium perfringens or Streptococcus faecalis) fed penicillin; bacteriology, growth, serum gamma globulin, and antibodies.


Bacteriological and cleaning studies on the mouthpieces of musical instruments.


Antibiotic inhibitors. III. Reversal of calcium inhibition of intestinal absorption of oxytetracycline in chickens by certain acids and acid salts.


Pyrogens, their mechanism of action and a few remarks on testing procedures.


The interactions between compounds containing various oxidation states of sulfur and bovine serum albumin.


Fractionation of a crude polysaccharase system by preparative paper chromatography and paper electrophoresis.


Methods for the qualitative, semiquantitative and quantitative determination of iodoamino acids and of inorganic iodide in iodoprotein digests and in human serum.


Mechanism of the antibacterial action of spermine.


The isolation of corticosterone metabolites from the urine of normal men.


The utilization in vivo of deuterio-C14 formate, labeled intramolecularly.


Polynucleotides. V. Titration and spectrophotometric studies upon the interaction of synthetic polynucleotides with various dyes.


Hydrogen isotope effects in the in vivo utilization of formate.


The influence of deoxyribonucleic acid on ultraviolet and visible light absorption of berberine.


The absorption in the rat of a 1,3-dioleyl-2-deuteriostearyl glyceride-C14 and a 1-monodeuteriostearyl glyceride-C14.


Hydrogen isotope effects in the oxidation of labeled formate in vivo.


Metabolism of C14-labeled ascorbic, dehydroascorbic and diketoglulonic acids in guinea pigs.


The metabolism of lens glutathione studies with glycine-C14.


Intracellular localization of carbonic anhydrase in rat liver and kidney tissues.


Reaction of gossypol with free epsilon-amino groups of lysine in proteins.


The influence of temperature on monolayers of bovine gamma-globulin.


The effect of cupric ion on the reaction inactivation of ascorbic acid oxidase.


The influence of temperature on monolayers of bovine serum albumin.


Environmental factors relating to tropolone formation by Penicillium stipitatum.


Casein and paracasein: neutralization with alkali, precipitation by calcium chloride and binding of calcium.


The reactivity of catechol amines, 5-hydroxyindoles and phenols with blut tetrazolium.


Influence of spectral composition of light on cis-trans interconversion of o-hydroxycinnamic acid.


Isolation, detection and measure of microgram quantities of labeled tissue nucleotides.


Studies on trimetaphosphate metabolism in yeast.


Cellulose-splitting enzymes. VI. Difference in the specificites of cellulase and beta-glucosidase from Irpex lacteus.


Hypotheses for and some kinetic studies with glutamine synthetase and acetate thiokinase.


Thermal inactivation of Escherichia coli phage T5.


A new color reaction for tryptophan or tryptophan-containing proteins.


Two neutral lipids from mitochondria specifically required for coenzyme Q function.


Effect of dinitrophenol on the interaction between myosin and nucleotides.


The structure of methostenol and its distribution in rat tissues.


Model copper oxidases; the cupric ion-catalyzed hydrogen peroxide oxidation of catechol.


Effect of freezing on the pH and composition of sodium and potassium phosphate solutions; the reciprocal system KH2PO4-Na2-HPO4-H2O.


The fatty acid composition of Rhodotorula graminis fat.


Oxidation and activation of unsaturated fatty acids.


Effect of modification of insulin on specific binding in insulin-resistant sera.


Intermediate metabolism of electric tissue in relation to function. II. Comparison of glycolysis rates in organs of Electrophorus electricus.


Vitamin D and citrate synthesis.

Vitamin D and citrate synthesis.


On the purification and kinetics of rat liver thetin-homocysteine transmethylase.


A colorimetric method for the measurement of the brain ammonia of the mouse; the effect of glutamine on the total measurable ammonia.


[Food values in the light of modern nutritional knowledge].


The radiation protective effects of AET on the enzyme creatine phosphokinase.


Linoleic acid and cholesterol metabolism in the rat. II. Effects of dietary cholesterol on plasma and liver ester composition.


The reactivity of sulfhydryl groups in bovine lenses.


Properties of tobacco polyphenol oxidase.


Studies on the metabolism of virus-infected tissues. II. The effect of influenza virus on ribonucleotide metabolism in chick chorio-allantoic membranes.


The stabilizing fraction of alpha-casein.


Preliminary studies on degradation products of quercetin in the rat's gastrointestinal tract.


The enzymic resolution of beta-methylaspartic acid with acylase II.


Quantitative nutritional studies with water-soluble, chemically defined diets. VII. Nitrogen balance in normal and tumor-bearing rats following forced feeding.


Studies on the structure of the vitreous body. VIII. Comparative biochemistry.


Distribution of gonadotropic hormone activity in the serum proteins of normal pregnant women and patients with trophoblastic tumors.


Quantitative nutritional studies with water-soluble, chemically defined diets. VIII. The forced feeding of diets each lacking in one essential amino acid.


Preparation and properties of 3-indoleacetaldehyde.


The catabolism of glucose and gluconate in Pseudomonas species.


The ultraviolet absorption spectra of benzoyl polyglycine anilides and benzoyl polyalanine anilides.


The preparation and purification of beta-galactosidase from Escherichia coli, ML 308.


Biosynthesis of glycogen from uridine diphosphate glucose.


The occurrence of ammonia-activiating enzyme in various organisms.


Ultracentrifugation and paper electrophoresis of highly active intrinsic factor preparations.


Phosphotransacetylase from extracts of green gram (Phaseolus radiatus).


Venous channel thrombosis as a possible cause of cerebral paralysis of early life.


Headaches in children.

Headaches in children.


A case of Fallots tetralogy with an atrioseptal defect complicated by a lung abscess.


Cancer: a collagen disease, secondary to a nutritional deficiency.


Relief of arthritic pain and rehabilitation of chronic arthritic patient by extended sympathetic denervation.


Management of the bladder in traumatic paraplegia.


A study of contractures in muscular dystrophy.


Effects of ultrasound on growing bone.

Effects of ultrasound on growing bone.


Role of the work classification unit of the Los Angeles County Heart Association.


Pathology of ovarian tumors.

Pathology of ovarian tumors.


Cardiac hypertrophy; some reflections.

Cardiac hypertrophy; some reflections.


Surgery of hemorrhoids, fissures and fistulas.


The third party problem.

The third party problem.


Contact dermatitis from cashew nut shell novelties.


BARROW Neurological Institute for Arizona; in memory of William E. Barrow.


Pudenal block anesthesia with nesacaine.


The two-year medical school.

The two-year medical school.


Blast and thermal effects, and radioactive fallout.


Early clinical manifestations of colon and rectum.


Primary pulmonary hypertension.

Primary pulmonary hypertension.


The holistic approach to peripheral vascular diseases.


Early days of the Arizona Medical Society.


ARIZONA Poisoning Control Center.

ARIZONA Poisoning Control Center.


[Report of a case of myoclonus epilepsy with patho-anatomical investigation].


[Preparation of museum macro-preparations].


[SOLOMON SAMUILOVICH VAIL'].

[SOLOMON SAMUILOVICH VAIL'].


Differentiation between rheumatoid arthritis and systemic lupus erythematosus by sheep cell agglutination tests.


Rheumatic manifestations of polymyositis and dermatomyositis.


Studies on adrenal cortical activity in patients with rheumatoid arthritis: the diurnal pattern and twenty-four hour levels of urinary total 17-hydroxycorticosteroids and 17-ketosteroids.


Protein patterns in synovial fluid and serum in rheumatoid arthritis and osteoarthritis.


Electrophoretic study of the serum factors responsible for the serological reaction in rheumatoid arthritis, with demonstration of two inhibitors.


Postmortem examination of an elderly severe hemophiliac, with observations on the pathologic findings in hemophilic joint disease.


Comparative distribution of proteins and glycoproteins of serum and synovial fluid.


Contacttype delayed hypersensitivity in patients with rheumatoid arthritis.


The choice of a uricosuric drug in gout.


Evaluation re-valued.

Evaluation re-valued.


Studies of the upper-extremity amputee. I. Design and scope.


Studies of the upper-extremity amputee. II. The population (1953-55).


Studies of the upper-extremity amputee. III. The treatment process.


Studies of the upper-extremity amputee. IV. Educative implications.


Reinforcement of wooden prostheses.

Reinforcement of wooden prostheses.


Below-knee prosthetics.

Below-knee prosthetics.


Porous laminates for upper-extremity prostheses.


The physician.

The physician.


Observations on kuru: II. Clinical features.


Observations on kuru. III. Pathological features in five cases.


Renal lesions in scleroderma: clinical and pathological features.


Early nephron changes: a microdissection study.


Marfan's syndrome: the nature of the aortic defect.


A survey of leukaemia in the Commonwealth.


A fatal case of acute phosphorus poisoning.


The adrenocortical response to corticotrophin in Addison's disease and panhypopituitarism.


Amenorrhoea and prolonged lactation, including a further report of the Chiari-Frommel syndrome.


The calcium infusion test: a discussion of the patterns found in various disorders.


Folic acid activity in the liver of sheep. I. The measurement of folic acid and citrovorum factor.


Folic acid activity in the liver of sheep. II. The effect of 4-amino-pteroylglutamic acid in vitro.


Adverse effect of filtration on the immunizing power of staphylococcal toxin and toxoid.


Folic acid activity in the liver of sheep. III. The effect of vitamin B12 deficiency on the concentration of folic acid and citrovorum factor.


The action of reserpine on the isolated heart.


The quantitative estimation of plasma corticosteroids by a modified chromatographic technique.


The possible clinical significance of elevations of the serum mucoprotein and hexosamine fractions in human disease.


Thrombin and the thromboplastic activity of plasma.


The effects of heavy metal ions on the human erythrocyte. II. The effects of lead and mercury.


Microbiological assay of vitamin B12 content of serum using Euglena gracilis.


The cytology of the pars distalis of the wallaby pituitary.


Hypercitricemia in human cancer: a preliminary report.


The management of grief situations in obstetrics.


QUIZ questions: gross anatomy.

QUIZ questions: gross anatomy.


A death due to chlorpromazine hepatitis.


On treating the whole person.

On treating the whole person.


Deaf-mutism; modern trends in treatment and prevention.


Examination of lipids in human sebum by disk chromatography.


The distribution of fall-out radio-strontium in a sheep skeleton.


Plasmalogen in ram semen, and its role in sperm metabolism.


Studies on pituitary polypeptide hormones. I. The structure of beta-melanocyte-stimulating hormone from pig pituitary glands.


Studies on pituitary polypeptide hormones. II. The action of pepsin and subtilisin on beta-melanocyte-stimulating hormone.


Studies on pituitary polypeptide hormones. III. The structure of alpha-melanocyte-stimulating hormone from pig pituitary glands.


Ketosis in the rat on a fat diet.

Ketosis in the rat on a fat diet.


Vitamin A1 aldehyde in the eggs of the herring (Clupea harengus L.) and other marine teleosts.


Esterases in the milk and blood plasma of swine. I. Substrate specificity and electrophoresis studies.


Esterases in the milk and blood plasma of swine. II. Activities at different stages during the lactation and suckling periods, and plasma arylesterase as a gene-controlled enzyme.


Lactic dehydrogenase and cytochrome b2 of baker's yeast; purification and crystallization.


The biochemistry of epithelia; hydrolytic enzymes of human bronchial epithelium.


A method for the assay of insulin by paper chromatography.


Protein breakdown in Bacillus cereus.

Protein breakdown in Bacillus cereus.


Mitochondrial preparations from the leaves of tobacco (Nicotiana tabacum).


Experiments on the origin of oak-bark tannin.


The action of certain drugs on the uptake of 32P by human erythrocytes.


Substrate specificity of phosphoprotein phosphatase from spleen.


Nephelometric determination of elastase activity and method for elastoproteolytic measurements.


The degradation of natural polyamines and diamines by bacteria.


A study of the cytochrome c haemochromogen.


Spectrum of horse-heart cytochrome c.

Spectrum of horse-heart cytochrome c.


Effect of fluoropyruvate on the swelling, phosphorylative activity and respiration of guinea-pig liver mitochondria.


An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals.


Studies of invertebrate collagen preparations.


The fatty acids of phosphatidylethanolamine and phosphatidylcholine from hen's egg.


Production of cleft palates in the offspring of mice treated with ACTH during pregnancy.


[Glycogen content changes in the nervous system and in the muscles in animals infected by vibrion septique].


Leukokinetic studies. I. A method for labeling leukocytes with diisopropyl-fluorophosphate (DFP32).


A serum with an albumin-active, auto-agglutinating property.


The anemia of the Di Guglielmo syndrome.


What are normal blood values for leukemia in remission.


Congenital hypoplastic thrombocytopenia with skeletal deformaties in siblings.


The effect of anemic anoxia on the cellular development of nucleated red cells.


Visual impairment due to optic neuropathy in pernicious anemia: report of case and review of the literature.


Normal functions of the spleen relative to red blood cells: a review.


Total cell counts of the bone marrow of normal albino rats from 1 to 50 weeks of age.


A comparison of human leukocyte phosphatase activity toward sodium beta-glycerophosphate, adenosine 5'-phosphate and glucose 1-phosphate.


Ferrtin and ferruginous micelles in normal erythroblasts and hypochromic hypersideremic anemias.


The polycythemia of high altitudes: iron metabolism and related aspects.


Preserved platelets: their preparation, storage and clinical use.


The utilization of protoporphyrin 9 in heme synthesis.


Studies on the biosynthesis of heme from iron and protoporphyrin.


Panel discussion on mediastinal tumors with presentation of cases.


Clinical features of cardiac tumors.

Clinical features of cardiac tumors.


The commonwealth of medicine.

The commonwealth of medicine.


[Kinetics of sulfamethoxypyridazine elimination from the blood].


Physiology of hypothermia.

Physiology of hypothermia.


Clinical aspects of induced hypothermia; methods of production and indications for its use.


The evolution of anaesthesia.

The evolution of anaesthesia.


The present trends of health in England and Wales.


Tuberculosis of the knee joint.

Tuberculosis of the knee joint.


Treatment of vaginal thrush with gyno-sterosan.


Influenza.

Influenza.


Multiple diverticulosis of the jejunum with perforation.


Exfoliative cytology; potentialities and limitations.


The significance of tachycardia.

The significance of tachycardia.


The early treatment of a major wound.

The early treatment of a major wound.


Diarrhoea.

Diarrhoea.


Haemoptysis and haematuria due to fat embolism.


Acute inversion of the uterus.

Acute inversion of the uterus.


Paediatrics.

Paediatrics.


Acrosclerosis: a disease sui generis or a variety of diffuse scleroderma.


Oral epithelial naevi.

Oral epithelial naevi.


Erythema nodosum: a study of seventy cases.


Letter from Munich.

Letter from Munich.


The training of the greatest of chest physicians: Laennec. II. Paris.


Bronchiolitis.

Bronchiolitis.


A psychosomatic aspect of asthma.

A psychosomatic aspect of asthma.


The bronchial spread of lung cancer.

The bronchial spread of lung cancer.


Chest deformities in congenital heart disease.


The value of cineangiocardiography in congenital heart disease.


Cavitation in pulmonary sarcomatous metastases with hypertrophic osteoarthropathy.


Fibroma of the trachea.

Fibroma of the trachea.


Pulmonary arteriovenous aneurysm.

Pulmonary arteriovenous aneurysm.


Erythema component of the primary Mantoux response.


Changes in erythema as the index of sensitisation and activation.


Ambulant chemotherapy: a practical advance in the treatment of pulmonary tuberculosis.


Short-term ACTH therapy for desensitisation against anti-tuberculosis drugs.


Some effects of staphylococcal and streptococcal toxins upon mammalian skin in tissue culture.


Effect of adjuvant (Freund's type) and its components on the organs of various animal species; a comparative study.


The immunological response of marrow-treated x-irradiated rabbits to bovine gamma-globulin.


Vascular pattern in the induced primary carcinoma of the liver of rats.


Studies on the multiplication of Mycobacterium lepraemurium in the mouse cornea.


The effect on experimental silicosis of hypersensitivity induced by horse serum.


The nature of the ground substance changes in experimental lathyrism and their effect on atherogenesis in cholesterol fed rabbits.


Growth, purification and maintenance of Leptospira on solid media.


Cultivation of sarcoidotic tissue from lymph nodes and skin.


Marrow treatment of irradiated dogs.

Marrow treatment of irradiated dogs.


The function of tryptophan in the adsorption of a bacteriophage.


A cytochemical study of oxidative enzymes in the parathyroid oxyphil cell and their functional significance.


Histochemical changes in rat kidney in magnesium deprivation.


Poliomyelitis virus flocculation: the reactivity of unconcentrated cell-culture fluids.


The immune-adherence activity of normal serum.


The influence of sodium fluoroacetate on regeneration of the rat's liver.


A comparative survey of the phagocytosis of different species of bacteria by Kupffer cells; perfusion studies with the isolated rat liver.


Antibody production by single cells. II. The difference between primary and secondary response.


Physical changes in the lungs during respiratory infection with Brucelia suis.


Experimental pyelonephritis: the effect of renal vein constriction on bacterial localisation and multiplication in the rat kidney.


A study on serotherapy of poliomyelitis in rhesus monkeys.


Observations on the interaction of poliovirus and host cells in vitro. II. The action of insulin.


The histological localization of renin with fluorescent antibody.


Observations on the pathogenesis of fibrosis in rats on a protein deficient diet.


Heterologous interference of experimental serum anaphylaxis in guinea-pigs; a preliminary report.


Some histological aspects of connective tissue metabolism in acute scorbutus.


The effect of bacterial endotoxin on resistance of mice to ectromelia.


Hepatic lesions and ascites in experimental long-term constriction of the inferior vena cava in the rat.


The effort to drive the other person crazy; an element in the aetiology and psychotherapy of schizophrenia.


An experimental approach to the psychopathology of childhood: sleep disturbances.


Recent maze test studies.

Recent maze test studies.


Anorexia nervosa: a contribution to its psychogenesis.


The assessment of anxiety states by rating.


Scientific methodology and The Dynamics of Anxiety and Hysteria.


Misconceptions in scientific methodology and The Dynamics of Anxiety and Hysteria.


Cataract extraction with the aid of alpha-chymo-trypsin.


Intracapsular cataract extraction using alpha-chymo-trypsin.


alpha-Chymo-trypsin in cataract extraction.


Sudden blindness in cranial arteritis.

Sudden blindness in cranial arteritis.


Diktyoma.

Diktyoma.


Operation on the vertical muscles in cases of nystagmus.


Seesaw nystagmus.

Seesaw nystagmus.


Tubadil in ophthalmic surgery; its effect on intra-ocular pressure.


Influence of protein deficiency and sex on the development of ocular lesions and survival time of the vitamin A deficient rat.


Malignant lymphatic tumours of the orbit; a review of eight cases.


Marfan's syndrome.

Marfan's syndrome.


The constancy of corneal curvature; an examination of corneal response to changes in accommodation and convergence.


The sanctity of corneal clarity and some contact lens fallacies.


Sight testing for the merchant navy.

Sight testing for the merchant navy.


Married women who work: their own and their children's health.


Sickness, change of residence, and death. I. General results of follow-up in two population groups.


Genotypic frequencies among close relatives of propositi with conditions determined by x-recessive genes.


On the nature of the determinants of congenital pyloric stenosis.


An estimate from pedigree data of the gene frequency for colour blindness.


Seasonal swing in mortality in England and Wales.


Five-year results of betatron x-ray therapy.


Radiological manifestations in tuberose sclerosis.


Radiological bone changes in tuberose sclerosis.


Quantitative evaluation of bone mineral by a radiographic method.


The change in the radiosensitivity of the intact mouse thymus produced by breathing nitrogen; with a note on the dosimetry for whole body fast electron irradiation.


Chronic appendicitis; some radiological observations.


Chronic appendicitis; some pathological observations.


A note on the distribution of radium and a calculation of the radiation dose non-uniformity factor for radium 226 and strontium 90 in the femur of a luminous dial painter.


Myelographic syndrome of caudad dislocation of the brain stem; changes in the position, mobility and form of the upper cervical spinal cord in cases of intracranial expanding lesions.


A viscous solution of sodium acetrizoate as a medium for hysterosalpingography.


Manifestations of yaws in Great Britain.


Effect of dosemeter size on measurements close to a radioactive source.


Small ionization chambers for direct reading of interstitial dose-rates.


A dose-rate calculator.

A dose-rate calculator.


A radium applicator for treatment of the penis.


An automatic dose computer for radiotherapy equipment.


A kilo-curie caesium 137 beam unit at Westminister Hospital: physical aspects.


A caesium 137 teletherapy unit for use at a source-to-skin distance of 35 cm.


Oesophageal and gastric varices.

Oesophageal and gastric varices.


Hyperplasia of Brunner's glands.

Hyperplasia of Brunner's glands.


Attempts to produce spatial avoidance as a result of exposure to x radiation.


The radiology of the bile ducts.

The radiology of the bile ducts.


Measurements of superficial absorbed dose with 2 MV x rays used at glancing angles.


The influence of x irradiation on the iodide-trapping mechanism of the human parotid gland.


Acute leukaemia following radioiodine therapy of thyrotoxicosis.


Leukaemia following irradiation in utero.


Leukaemia following irradiation for ankylosing spondylitis.


An unusually large subphrenic abscess.

An unusually large subphrenic abscess.


Construction of orthoradiographic projections from a standard radiograph for stereotaxic measurements.


A hydrostatic pressure chamber for the formation of lead face masks used in x-ray therapy.


A new camera for use with the image intensifier.


An apparatus for loading and unloading ovoids.


Peripheral vascular grafts; experimental comparison of autogenous veins, homologous arteries, and synthetic tubes.


Some observations on the cause and treatment of hare-lip and cleft palate, based on the treatment of 1041 patients.


Angiosarcoma in post-mastectomy lymphoedema; a report of 5 cases and a review of the literature.


A method of carotid ligation.

A method of carotid ligation.


The indications for and limitations of frozen section diagnosis; a review of 1269 consecutive frozen section diagnoses.


Cardiovascular changes in the post-gastrectomy syndrome.


Corrosive stricture of the stomach; case report and review of literature.


Intramural gastric tumours; report of three cases.


Pus collections in hernial sacs; an unusual complication of general peritonitis.


Leiomyosarcoma of cervical stump following subtotal hysterectomy.


Severe melaena due to a leiomyoma of the duodenum.


A case of myxoma of the left atrium with peripheral arterial emboli.


Aneurysm of the main pulmonary artery.

Aneurysm of the main pulmonary artery.


Lymphangio-endothelioma of the anterior abdominal wall; report of a case.


Granuloma of the stomach.

Granuloma of the stomach.


Haemophilic blood cysts.

Haemophilic blood cysts.


Duodenal megabulbus and annular pancreas.


Gastric cancer in young adults.

Gastric cancer in young adults.


Acceleration of wound healing produced by preliminary wounding.


Tension pneumoperitoneum; a report on two cases.


Intestinal hypertrophy following partial resection of the small bowel in the rat.


Bilateral synchronous posterior dislocation of the shoulder.


Report of a case of intestinal obstruction due to renal calculus.


Enlarged lymphatic glands in a case of multiple pigmented naevi.


Benign granular-cell myoblastoma of the bronchus.


A complication resulting from the use of a rigid inlay in the repair of an inguinal hernia.


Torsion of fatty tag in falciform ligament simulating perforated peptic ulcer.


Surgical diagnosis of chronic pancreatitis and chronic relapsing pancreatitis.


Osteomalacia; pathogenesis and treatment.


Systemic candidiasis and endocarditis due to C. tropicalis.


Melioidosis.

Melioidosis.


Induction of sarcoma in the rat by iron-dextran complex.


Charcot's arthropathy following intra-articular hydrocortisone.


Symptomless myelomatosis.

Symptomless myelomatosis.


Suppository treatment of haemorrhagic proctitis.


DOSE OF accidental radiation.

DOSE OF accidental radiation.


INTIMAL haemorrhage.

INTIMAL haemorrhage.


VENOUS shunts in cirrhosis of the liver.


OSTEOMALACIA.

OSTEOMALACIA.


ESCAPE from sinking aircraft.

ESCAPE from sinking aircraft.


HEALTH service estimates.

HEALTH service estimates.


MAXIMUM permissible dietary contamination after the accidental release of radioactive material from a nuclear reactor; report to the Medical Research Council by its Committee on Protection Against Ionizing Radiations.


SIR ROBERT MUIR.

SIR ROBERT MUIR.


F. CHARLOTTE NAISH.

F. CHARLOTTE NAISH.


Exercise and heart disease; a study in regional circulation.


VACCINATION against whooping-cough; the final report to the Whooping-Cough Immunization Committee of the Medical Research Council and to the medical officers of health for Battersea and Wandsworth, Bradford, Liverpool, and Newcastle.


Cystitis of ascending origin in the male.


Hyperbilirubinaemia and kernicterus in premature and full-term Bantu newborn infants.


Emotional disturbances of burned children.


Peripheral effects of vasculit.

Peripheral effects of vasculit.


Sacro-iliitis in Reiter's disease.

Sacro-iliitis in Reiter's disease.


Lethal hazards of the Inteal phase of the menstrual cycle.


The pulled elbow.

The pulled elbow.


Hypertelorism associated with poor frontal development of skull and bilateral Sprengel's shoulders.


Vesico-vaginal fistula associated with retention of urine.


CENTRAL African medical school.

CENTRAL African medical school.


PROTECTION against whooping-cough.

PROTECTION against whooping-cough.


MOLLUSCUM sebaceum.

MOLLUSCUM sebaceum.


FOOD-POISONING and food hygiene.

FOOD-POISONING and food hygiene.


HAEMATURIA in boxers.

HAEMATURIA in boxers.


STERILE eye drops.

STERILE eye drops.


The oestrogens.

The oestrogens.


Operational research in the university.

Operational research in the university.


Veritas examinations at Harvard Medical School in 1958.


W. H. BROWN.

W. H. BROWN.


F. C. REIDY.

F. C. REIDY.


The hereditary haemorrhagic diseases: their classification and diagnosis.


Adult leukaemia; trends in mortality in relation to aetiology.


P.T.C. taste response and thyroid disease.


Treatment of heart failure in haemochromatosis.


Increased thyroid function in haemochromatosis.


A comparison of the responses of 100 infants to primary poliomyelitis immunization with two and with three doses of vaccine.


Treatment of cardiac shock by metaraminol.


Smoking habits of monozygotic and dizygotic twins.


Phenylbutazone and its derivatives with special reference to G.27202.


A case of anaemic gangrene of the bowel.


RADIATION and leukaemia.

RADIATION and leukaemia.


LUNG CANCER and constitution.

LUNG CANCER and constitution.


RESPIRATORY paralysis.

RESPIRATORY paralysis.


GAS CYSTS of intestine.

GAS CYSTS of intestine.


A CASE of chronic tuberculosis.

A CASE of chronic tuberculosis.


Coronary artery disease. I.

Coronary artery disease. I.


Psychosomatic disorders in children.

Psychosomatic disorders in children.


E. FARQUHAR MURRAY.

E. FARQUHAR MURRAY.


Partial gastrectomy and peptic ulcer.

Partial gastrectomy and peptic ulcer.


Alimentary bleeding of obscure origin; a follow-up study and commentary.


Post-vagotomy diarrhoea: its cause and prevention.


Vancomycin: report on treatment of patients with severe staphylococcal infections.


OCCURRENCE of tetanus spores in materials used for dressing wounds.


Red-cell aplasia and benign thymoma; studies on a case responding to prednisone.


Relation between maximal urine concentration, maximal water reabsorption capacity, and mannitol clearance in patients with renal disease.


Role of osmotic diuresis in impairment of concentrating ability in renal disease.


A congenital blood-clotting anomaly resembling coumarin-induced defect.


Effect of castor oil, soap enema, and hot bath on the pregnant human uterus near term; a tocographic study.


Subserous jejunal haemorrhages during mecamylamine therapy.


A hand-operated resuscitator.

A hand-operated resuscitator.


MEDICAL ethics.

MEDICAL ethics.


COLLEGE of pathologists.

COLLEGE of pathologists.


POST-GASTRECTOMY syndromes.

POST-GASTRECTOMY syndromes.


DANGEROUS toys.

DANGEROUS toys.


THYMOMA and red cell aplasia.

THYMOMA and red cell aplasia.


Coronary artery disease. II.

Coronary artery disease. II.


The tardy convalescent.

The tardy convalescent.


Respiratory difficulties at birth.

Respiratory difficulties at birth.


Smoke vapours and carcinogenesis.

Smoke vapours and carcinogenesis.


JOHN HAY.

JOHN HAY.


A. C. ALPORT.

A. C. ALPORT.


[Henri Vaquez; 1860-1936].

[Henri Vaquez; 1860-1936].


BREAKDOWN in doctor-patient relationship is shown by malpractice suits, say psychologist in C.M.A. study.


Resurgence of interest in medical history.


The role of the administrator in a teaching hospital.


Medical education in a community hospital.


Is your emergency ward an asset or a liability to your hospital.


THE RETARDED children's clinic at Georgetown.


BLAIN; 1885-1958.

BLAIN; 1885-1958.


Compensation of residents in the federal services.


Medical student training positions.

Medical student training positions.


Portraits of Georgetown.

Portraits of Georgetown.


The afferent-loop syndrome; report of a case and a clinical discussion.


Observations on disturbances in neuromuscular coordination in patients with malignant disease.


Treatment of congenital club foot.

Treatment of congenital club foot.


The weight stream in Charcot disease of joints; the cure of perforating ulcer of the foot.


[Bilateral germ tumors of the testis].

[Bilateral germ tumors of the testis].


Inversion instability of the ankle following poliomyelitis.


A new mechanical injector device for contrast visualization of the vascular system.


Spontaneous rupture of the extensor pollicis longus tendon in rheumatoid arthritis.


Fracture dislocation of the ankle joint with trapping of the fibula behind the tibia.


An atypical osteoid osteoma of the ilium with sciatic syndrome.


Congenital spinal extradural cyst.

Congenital spinal extradural cyst.


Dysplasia epiphysalis multiplex.

Dysplasia epiphysalis multiplex.


Pelvic fixation for femoral neck fractures (intraarticular fixation with two nails.


Tendon passer for hand surgery.

Tendon passer for hand surgery.


Connective tissue studies. I. Relation of dietary and tissue levels of ascorbic acid to the healing of surgically-induced wounds in guinea pigs.


Stretch effects in human extraocular muscle; an electromyographic study.


Self-realization and mental health.

Self-realization and mental health.


The cytochemical localization of oxidative enzymatic activity and glycogen in frog striated muscle.


Discovery of the gifted child; new materials and techniques for the early detection of unusual intellectual ability.


The sanity hearing.

The sanity hearing.


Community reactions to a horrifying event.


Primary carcinoma of the liver.

Primary carcinoma of the liver.


The fate of sodium and water in the renal tubules.


Megacystis and megaureter in children.

Megacystis and megaureter in children.


The clinical significance of small polypoid tumors of the stomach.


The present day meaning of insight.

The present day meaning of insight.


Prognosis in Still's disease.

Prognosis in Still's disease.


Current problems in peripheral arterial surgery.


A re-evaluation of tribromoethanol anesthesia for cardiac catheterization; our experience with avertin in cardiac catheterization: a review of 300 cases.


Pericardial cysts and diverticula.

Pericardial cysts and diverticula.


Tofranil, a new anti-depressant.

Tofranil, a new anti-depressant.


Ganglioneuroma arising from the superficial cardiac plexus.


The mucopolysaccharides in the aging of human arterial tissue.


Evaluation of the health hazards involved in house-spraying with DDT. The dermal and respiratory exposure of workers during house-spraying operations has been measured to find out the main factors affecting the exposure, and to develop effective, acceptable protective measures and clothing. Dermal exposure was found to be much greater than respiratory exposure. The major factors affecting exposure with a single concentration of formulation appeared to be spray-pump pressure, height of area being sprayed, and absorbency of surface. Temperature, type of formulation, and nozzle size had little or no effect on exposure. A plastic cape, a hard hat with a plastic visor, and rubberized gauntlet gloves gave a fully clothed man almost complete protection from dermal and respiratory exposure. A tropical helmet equipped with a plastic-netting veil is proposed for field testing. This equipment gave good protection of the shoulders, back, and chest and excellent protection of the face and neck.


Exposure of spray-men to dieldrin in residual spraying. A study of the exposure of spray-men to dieldrin was made in a pilot scheme of residual spraying in the Taveta-Pare area of East Africa. A detailed work study was completed on the operators, and sources of contamination were enumerated. Filter paper pads were placed on the skin and outside clothing and the pick-up was estimated chemically. A spray-man, while using the daily average of 2.12 kg (4.7 pounds) of dieldrin and observing the protective measures laid down, received a dermal exposure of 1.8 mg of dieldrin per kg of body-weight per day. This was possibly reduced somewhat by washing with soap and water upon completion of each day's work. The sixteen spray-men and assistants were exposed for 180 days per year and there was an interim period of 2 months between spray cycles. No clinical symptoms of poisoning were observed.Comparison is made with certain programmes where dieldrin poisoning has occurred. Attention is drawn to the reduced time of exposure in the Taveta-Pare scheme, personal washing, the great value of protective clothing and of its daily washing in soap and water and the need to use a dilute suspension of wettable powder for spraying.


Pyrimethamine resistance in Plasmodium vivax malaria. P. vivax infection (Korean, St Elizabeth or Chesson strain) was induced in 17 neurosyphilitic patients. Pyrimethamine in single doses of either 25, 50, 100 or 200 mg was given to test the schizontocidal and sporontocidal effects.The first single-dose treatment of 25 mg or 100 mg was given between the 8th and 61st days of parasite patency and gave moderately rapid schizontocidal and very rapid sporontocidal effects. All observed cases relapsed.The second treatment, usually three weeks or longer after the first and with the same or higher doses, had either a diminished effect or none on the schizogonous and sporogonous cycles. Subsequent treatment, even at weekly intervals, had no effect.The resistant quality was undiminished in subsequent infections transmitted by mosquito bites, by the injection of preserved sporozoites, or by transfusion of infected blood. Preserving sporozoites or erythrocytic parasites at very low temperatures did not materially affect the resistant quality.In view of the evidence presented, it appears that resistance could also occur in the field when large single doses of pyrimethamine alone are given at less than monthly intervals to febrile persons having active P. vivax infections.


The development of pyrimethamine resistance by Plasmodium falciparum. Sixteen patent P. falciparum infections (McLendon and Panama strains) in non-immunes were treated with single doses of pyrimethamine. The schizontocidal and sporontocidal response to the initial dose was rapid.Seven blood-induced infections, of which three were treated with 100 mg and four with 50 mg, did not relapse. Of seven cases observed after 25-mg treatment, five relapsed.Delayed treatment of the relapsing infections (Panama strain) with single doses of 25 mg or 50 mg, and subsequently 100 mg, had virtually no schizontocidal or sporontocidal effect. In one case the resistant infection was transmitted by mosquitos to another patient; the subsequent infection was also highly resistant to the drug.It is concluded that under the experimental conditions of this study resistance to pyrimethamine by P. falciparum may occur rapidly after a single dose of 25 mg, being manifested during relapses on the second challenge with the drug. Increasing the drug dosage does not overcome the resistance. The resistant character is readily transmitted by mosquitos.


Morphology and development of the salivary glands and their chromosomes in the larvae of Anopheles stephensi sensu stricto. In the larvae of Anopheles stephensi s. s. five typically banded salivary chromosomes are present united proximally to a chromocentre. Maps have been constructed to illustrate their constant and characteristic banded pattern. Chromosome IIIR, however, has shown a variation in the form of a heterozygous inversion. The chromocentre is a small, fragile body, closely associated with the large nucleolus.The development of the salivary glands in the larva is by cell-growth. The chromocentre appears at first as a heteropycnotic "crescent", which soon gives place to a disc-shaped body. Later on in development the chromocentre loses both its heteropycnotic nature and compactness. The nucleolus persists until the time of histolysis of the glands, which begins at the distal end of the gland and gradually involves the more anterior regions. At the earliest observable stage the homologous chromatin elements constitute a tight coil. Full synapsis is preceded by a process of uncoiling accompanied by a chromomere-to-chromomere fusion. The rate of this process varies among different pairs of homologues and along different regions of the same pair. Synapsis is completed in the late third instar larva.RNA is localized in the cytoplasm and the nucleolus of the larval salivary gland cells. The chromosomes and the chromocentre include DNA. A faint reaction of the interband areas show that DNA is present in a diffuse state throughout the chromosomes.


Studies on insecticide-resistant anophelines. 2. Chromosome arrangements in laboratory-developed DDT-resistant strains of Anopheles atroparvus. The development of several DDT-resistant strains of Anopheles atroparvus is described. They were selected by larval treatment only (RL), selection of larval and adult females (RLAF), and selection of adult females and males (RAFM). Their rate of DDT-resistance was measured in the larval and adult states (mainly in the 32nd generation). The results were compared with those of a dieldrin-selected strain (R/dieldrin) and several normal and semi-normal reference strains. In the larval assay DDT-resistance was of the following order: RL>RLAF>RAFM>R/dieldrin. Topical application to adults gave: RLAF>(RL?)>RAFM>R/dieldrin; while adult tarsal contact gave: RAFM>RLAF>RL>R/dieldrin These different orders of resistance are discussed.The strains were subjected to cytological examination by the method of Frizzi. The percentages of heterozygous inversions found were as follows: R/dieldrin, 77.4%; RL, 55.3%; RLAF, 54.0%; RAFM, 24.4%; all normal and semi-normal strains about 12%-21%.The rate of DDT-resistance could not be correlated with the percentages of heterozygous inversions found in the various strains.


The susceptibility and resistance of Bulinus (Physopsis) globosus and Bulinus (Bulinus) truncatus rohlfsi to two strains of Schistosoma haematobium in Ghana. The author presents the results of some laboratory experiments carried out to determine the susceptibility of the snail vectors of bilharziasis in Ghana to local strains of Schistosoma haematobium, isolated from children living in two districts near Accra: the Ke district, where Bulinus (Bulinus) truncatus rohlfsi is the important snail vector, and the Pokoasi district, where Bulinus (Physopsis) globosus is the exclusive intermediate host.Each strain was found to be virtually specific in its ability to develop in one or other of the vector species. The "Ke strain" developed readily in B. (B.) truncatus rohlfsi but not in B. (P.) globosus, while the "Pokoasi strain" developed readily in the latter snail but not in the former.The author points out that these findings provide a possible explanation for some of the conflicting observations that have been reported by workers in other African territories, and may have an important bearing on the epidemiology of urinary bilharziasis in Africa as a whole. He stresses the need for further studies on the relationship between bulinid snails and schistosome strains in Africa.


The fox as a definitive host of Echinococcus and its role in the spread of hydatid disease. In the first part of this discussion of the significance of the fox in the epidemiology of hydatid disease in man, the author reviews the literature on vulpine echinococciasis. He points out that the evidence available from field surveys and laboratory observations suggests that the fox is not a definitive host of Echinococcus granulosus-the parasite responsible for the most common form of hydatid disease in man-but is a host of E. multilocularis, which is found in parts of Europe and Asia, in the islands of the Bering Sea and in Alaska, and is known to be the causal agent of alveolar hydatid disease.In the second part, the author presents the results of experimental infestation of the European red fox (Vulpes vulpes) with the Australian strain of E. granulosus. These results indicate that a few tapeworms became established in some of the foxes, but were retarded in growth (as compared with their growth in the dogs used as controls) and failed to reach sexual maturity (production of ova) even 112 days after infestation. The author therefore concludes that the fox plays no role in the spread of hydatid disease caused by E. granulosus in Australia.Finally, the author discusses the etiology of two autochthonous cases of alleged alveolar hydatid disease in man in Australasia, putting forward two alternative hypotheses to explain their occurrence.


Some general remarks and new observations on psittacosis and ornithosis. Complement-fixation tests of sera from patients with mild or obscure respiratory infections have shown that psittacosis is more prevalent in man than the occasional dramatic outbreaks had hitherto led one to suppose. In this paper, the author discusses the epidemiology of the disease in humans with special reference to the various sources of infection, which are now known to include a number of non-psittacine birds-particularly, turkeys, ducks and pigeons.After reviewing the distribution of human infection, describing the methods of diagnosing the infection in man and birds, and outlining briefly the mechanism of immunity, the author proceeds to the question of therapy with tetracycline compounds, which have proved effective for the treatment of human psittacosis provided that they are administered soon enough and over a sufficiently long period. He then deals with the public health aspects of the disease and with the problem of control, pointing out the many difficulties involved. Addition of tetracycline compounds to the feed has been successful in eradicating the infection from a few parakeet-breeding aviaries, but the results with parrots, pigeons and turkeys have been less promising; it is hoped, nevertheless, that a suitable chemotherapeutic method can be developed.Finally, the author reviews briefly the known instances of infection of mammals other than man with viruses of the psittacosis group.


Improvement of the antigenicity of antirabies vaccine by pooling checked by post-challenge vaccination of guinea-pigs. The author describes some studies carried out at the Pasteur Institute of Southern India, Coonoor, with the object of developing an antirabies vaccine of uniform potency.It was found that by pooling batches of vaccine from several infected sheep brains a vaccine was produced which was superior in antigenicity (as determined by potency tests in mice) to the NIH (United States National Institutes of Health) Reference Vaccine 155-D as well as to most of the individual batches of vaccine tested. Furthermore, the pooled vaccine conferred a significant degree of protection on guinea-pigs challenged with virulent strains of street virus, even when not administered until an hour after infection.A brief outline is given of the method used for pooling the vaccine.


A survey of oral health, Qalyub project, Egypt. This report presents the results of an oral health survey of 4324 individuals in three villages near Cairo, Egypt.The results show that the incidence of dental decay (expressed as the number of carious teeth per individual) in this group of Egyptians was lower than that reported for the over-all population of the USA, and that the prevalence of periodontal disease in the group studied was about three times as high as that reported in the USA.There was a statistically significant relationship between the occurrence of asymptomatic enlargement of the parotid glands and the occurrence of angular cheilosis in the same individuals. Other forms of oral disease were observed infrequently.Water samples from the survey area were assayed for fluorides and were shown to contain fluoride levels below that considered to give protection against dental caries.


Anisol; a convenient immersion medium for microscopy.


Effect of changes of temperature on the susceptibility to dieldrin of adult Aëdes aegypti.


Measurement of adsorption of residual insecticides using flowing chromatography.


Anticoagulant drug treatment of coronary artery disease. Anticoagulant therapy of arteriosclerotic heart disease may prove to be most valuable when applied on a long-term basis for prevention of recurrent myocardial infarction. While its prophylactic value in impending infarction has not been established, at least the accepted treatment for the acute stage is already begun if an anticoagulant has been administered before an inevitable infarction occurs. The chief value of the anticoagulant, though, seems to lie in preventing cardiac mural thrombosis and extracardiac thromboembolism. It is by this effect, apparently, that mortality has been reduced by 50 per cent among survivors of myocardial infarction who receive continuous dicoumarin therapy. While the danger of hemorrhage is still present, it is being steadily reduced by increasing skill in the management of anticoagulant therapy, and for a long time the risk has been far outweighed by the reduction in coronary occlusion. Physicians have a duty to learn the use of anticoagulant therapy, obtain the facilities necessary for it, and apply it to patients who are able and willing to cooperate in prolonging their useful lives.


Nonverbal treatment of neurosis; techniques for general practice. "Psychosomatic medicine" does not demand that the general practitioner function as a psychiatrist; rather, it is a psychiatric orientation that can increase the effectiveness of purely medical treatment for such conditions as neuroses. The general practitioner to whom the patient turns may achieve permanent results with nonverbal techniques where formal psychotherapy would be impracticable or unacceptable. The first aim is to relieve pressure so that the patient can regain his mental balance and thereby his self-confidence. Arts, hobbies, sports, and the like can be prescribed rather specifically according to the patient's personality and needs. Nutrition can be improved simply at first by prescribing needed additions to diet rather than imposing restrictions. Vitamin deficiency may by itself be the cause of neurosis or more serious mental disease, whereas psychic stress by itself may create a need for additional vitamin intake. Hormone therapy may be extremely helpful but must be based on clear indication and limited to specific purposes. Since lack of sleep and rest quickly impairs mental function, it is important for neurotic persons to learn relaxation as a necessity for sleep. Sedatives may be used in a crisis but should be abandoned as soon as possible. With all drugs there are problems of excess and habituation. The least, the mildest, the shortest dosage is the ideal. THE INITIAL STEPS OF PSYCHOTHERAPY ARE AVAILABLE TO ANY PHYSICIAN: Establishing rapport, noting how complaints are stated, encouraging ventilation, winning confidence rather than immediate results.


Crushing injury of the hand; prevention of ischemic contracture. Crushing injury of the hand usually causes "explosive" damage. Subsequent swelling of the palmar structures further impairs venous outflow, and hemorrhage into structural spaces increases the pressure. The arterial system and the large dorsal veins, however, are seldom obstructed and provide adequate circulation unless hampered by improper bandaging. A bandage that compresses the dorsal veins causes back-pressure, which increases the swelling further and brings about ischemia. Swelling and pain cause the patient to restrict exercise of the injured hand, which permits contractures to develop. The author has averted this sequence in more than 100 cases by preserving integrity of veins during debridement, arresting hemorrhage, bandaging the hand with compression dressings in functional flexion, and reducing swelling with hyaluronidase. In these cases, on removal of bandages in 24 hours, swelling was reduced and continued to diminish. All patients exercised the hand at this time without discomfort and only a few required aspirin for pain.


Congenital heart disease; comments regarding incidence and natural history. The incidence of congenital heart disease is approximately 1 per cent of all live births. Approximately 60 per cent of patients who die of congenital heart disease do so at less than two years of age. Very few patients with such lesions live beyond 45 years at the very most. In about 70 per cent of patients who are born with cardiac anomalies, the lesions are either of kinds that are already being operated upon successfully or for which operations are now being attempted and often are helpful.