The transplantability of strain-specific and nonspecific mouse tumors to pretreated rats.


Natural agglutinis in rat sera against cells of mouse tumors differing in their transplantability to pretreated rats.


Electron microscopy of avian lymphomatosis virus propagated in tissue culture.


Some systemic effects of toxohormone.

Some systemic effects of toxohormone.


Postoperative electrocardiographic modifications; a study of 260 operated cases.


Cell metabolism of the overloaded mammalian heart in situ.


The Wolff-Parkinson-White syndrome and second degree heart block; report of a case and a discussion of the significance of the association of these phenomena.


Complete interruption of the aortic arch with transposition of the great vessels; report of a case diagnosed in-vivo.


THE FLEMING letters.

THE FLEMING letters.


Epilepsy and its variations.

Epilepsy and its variations.


Medullary nailing.

Medullary nailing.


Endocrine disorders and peptic ulcer.

Endocrine disorders and peptic ulcer.


Anaesthesia in obstetrics.

Anaesthesia in obstetrics.


The writing of medical papers.

The writing of medical papers.


Chieng Mai squat pans for pit latrines.

Chieng Mai squat pans for pit latrines.


[Heteropia of the macula lutea].

[Heteropia of the macula lutea].


Differential conditioning by children as a function of effort required in the task.


Teachers' and clinicians' attitudes toward the behavior problems of children: a reappraisal.


Some relationships between maternal attitude factors and authoritarianism, personality needs, psychopathology, and self-acceptance.


A contribution to research in the area of the mother-child relationship.


Racial comparisons and additional normative data on the children's manifest anxiety scale.


Children's concepts of justice: a comparison with the Piaget data.


Learning by imitation in kindergarten children.


Auditory localization and adaptation to body tilt: a development study.


Perceived similarity to parents and adjustment.


The relationship between children's expression of hostility and methods of discipline exercised by dominant overprotective parents.


Parental attitudes and child adjustment.


The effect of verbalization in children's learning as a function of chronological age.


Permissiveness, permission, and aggression: the effect of adult presence or absence on aggression in children's play.


Positive reinforcers for experimental studies with children; consumables and manipulatables.


Advice seeking of mothers as a function of need for cognition.


Rheumatic fever in the adult: criteria and implications.


Atrial flutter as a manifestation of digitalis toxicity.


Clinical study of twenty-three cases of Ebstein's anomaly of the tricuspid valve.


Atrial septal defect: factors affecting the surgical mortality rate.


Serum cholesterol in man: diet fat and intrinsic responsiveness.


Severe acidosis and hyperpotassemia treated with sodium bicarbonate infusion.


Congenital aneurysms of the coronary arteries with report of a case.


Biochemical alterations in blood in obliterative atherosclerosis.


The pulmonary diffusing capacity in congenital and rheumatic heart disease.


Familial pseudoxanthoma elasticum and valvular heart disease.


The electrocardiogram of the South African Bantu.


Determinants of the left atrial pressure pulse in mitral valve disease.


Cardiac chamber volumes and their significance in rheumatic heart disease with isolated mitral stenosis.


Beriberi heart disease.

Beriberi heart disease.


Hyponatremia.

Hyponatremia.


Serum parameters as discriminators between normal and coronary groups.


Disseminated nodular pulmonary ossification in patients with mitral stenosis.


Atypical patent ductus arteriosus; the use of a vasopressor agent as a diagnostic aid.


The growth of the normal aorta and of the anastomotic site in infants following surgical resection of coarctation of the aorta.


So-called primary venous obstruction in the upper extremity: Paget-Schroetter syndrome.


Effects of chlorothiazide on specific renal functions in hypertension.


Depressive reactions in hypertensive patients; a comparison of those treated with Rauwolfia and those receiving no specific antihypertensive treatment.


A mechanism of chlorothiazide-enhanced effectiveness of antihypertensive ganglioplegic drugs.


The forces needed to evoke sounds from cardiac tissues, and the attenuation of heart sounds.


The role of vessel tone in maintaining pulmonary vascular resistance in patients with mitral stenosis.


Blood pressure studies in rural and urban groups in Delhi.


Highvoltage QRS complexes in the absence of left ventricular hypertrophy.


False coronary patterns in the infant electrocardiogram.


Biochemical studies in full-blooded Navajo Indians.


Electrocardiographic response to exercise in patients with mitral stenosis.


Time and concentration components of indicator-dilution curves recorded following central injections of dye in normal human subjects.


Staphylococcal bacteremia and endocarditis.


Congenital aortic stenosis.

Congenital aortic stenosis.


Schizophrenia in research.

Schizophrenia in research.


An analysis of coronary flow and related factors following vagotomy, atropine, and sympathectomy.


The interpretation of spurious correlations in coronary flow literature.


Activation of the free wall of the right ventricle in experimental right bundle branch block.


Observations concerning both the induction and the regression of lipid and cholesterol infiltration in ocular implants of rabbit aorta.


Synthesis of precordial potentials from the SVEC III vectorcardiographic system.


Epinephrine levels in the peripheral blood during irreversible hemorrhagic shock in dogs.


Comparative reactivities of aortic strips from hypertensive and normotensive rats to epinephrine and levarterenol.


Effects of testosterone and castration on cholesteremia and atherogenesis in chicks on high fat, high cholesterol diets.


Effect of chylomicrons on the fibrinolytic activity of normal human plasma in vitro.


Influence of prolonged hypothermia and hyperthermia on myocardial sodium, potassium and chloride.


Arterial wall potassium in renal hypertensive rats.


Effect of taurine, glycine and beta-sitosterols on serum and tissue cholesterol in the rat and rabbit.


Electrical activation and mechanical asynchronism in the cardiac cycle of the dog.


A biochemical study of spontaneous atherosclerosis in pigeons.


Response of subcutaneous vessels to venous distention.


Observations on the microcirculation in the gingiva of hamsters and other laboratory animals.


Properties of hyperthyroid rat myocardium.


Directional difference of conduction velocity in the cardiac ventricular syncytium studied by microelectrodes.


Effect of nicotine on cholesterol-induced atherosclerosis in the rabbit.


The electric field produced by an eccentric dipole in a homogeneous circular conducting lamina.


Effect of hemorrhage on hepatic blood flow determined by radioactive colloidal chromic phosphate removal.


[Preoccupations in the case of the bones].


Proteins, friend and foe of better mankind.


Comparative studies of the protein fractions from human gastrointestinal juices with paper electrophoresis combined with various detection methods.


Coloured substances as an experimental tool in the study of electrophoretic techniques.


Purification and properties of different haptoglobins.


Isolation and description of a few properties of the beta 2A-globulin of human serum.


Development of foetal proteins.

Development of foetal proteins.


Electrophoretic protein and polysaccharide patterns in tuberculosis and amyloidosis.


Utilization of protein in the small intestine.


Serum iron and iron-binding capacity in clinical diagnosis.


Assay of thiamine in biologic fluids.

Assay of thiamine in biologic fluids.


Urinary 17-ketosteroids in various endocrine disorders.


The rapid determination of calcium in biologic material.


Determination of magnesium and calcium in urine.


Automatic titration of calcium or magnesium in blood serum.


Micro determination of glutamic-oxalacetic transaminase in blood serum.


A system of clinical chemical analysis.

A system of clinical chemical analysis.


Psychological problems in the management of a diabetic child.


Lactic dehydrogenase in the cerebrospinal fluid of children: a preliminary report.


Mushroom poisoning.

Mushroom poisoning.


Clinical brief: a case of cat scratch disease complicated by erythema nodosum.


[Use of embryonic organ cultures in the culture of pathogenic viruses].


Physiology and pathologic physiology of the stomach.


[New reflections on shared expenses].

[New reflections on shared expenses].


Neuroectodermal and other cells in mouse-brain tissue cultures; their morphologic relation to cell-types found in human neuroectodermal neoplasms.


Advances in upper gastrointestinal surgery.


A study of constituents of the bloods of mother and infant at birth.


Congenital tracheoesophageal fistula.

Congenital tracheoesophageal fistula.


Influenza vaccination; 1958.

Influenza vaccination; 1958.


Convulsions in infancy and childhood.

Convulsions in infancy and childhood.


Some emotional uses of foods.

Some emotional uses of foods.


Freedom of choice.

Freedom of choice.


Care of the aging.

Care of the aging.


The diagnostic use of radioactive iodine in thyroid disorders.


Occlusion of the middle cerebral artery; an analysis of thirty-six arteriographed cases.


The arteriographic and electroencephalographic findings in cerebral apoplexy.


The basophilic substance of the gastric chief cells and its relation to the secretory process; summary of thesis.


Toxic effect of menadione sodium bisulfite in premature infants.


Medicostatistical information from Denmark for the years 1956 and 1957.


Sarcoma of the stomach.

Sarcoma of the stomach.


THE MANAGEMENT of pulmonary tuberculosis.


AMEBIASIS.

AMEBIASIS.


Squamous cell carcinoma arising in discoid lupus erythematosus.


Growth of Candida parapsilosis with keratin as sole source of nitrogen.


Newer viruses.

Newer viruses.


A histochemical study of some of the hydrolytic enzymes in leprosy.


Gastrointestinal malabsorptive syndromes.


Physiology and pharmacology of the skin 1957/58.


Experience with chlorothiazide (diuril) in hypertensive patients.


Mothers' milk bank at the Delaware Hospital.


Retroperitoneal hemangiopericytoma associated with hypoglycemia and masculinization.


Combined roentgen therapy and hematoporphyrin for spontaneous mammary carcinoma in mice.


[Surgery of intracerebral hemorrhage].

[Surgery of intracerebral hemorrhage].


Impaired glucose tolerance and glucosuria induced in man by repeated injections of glucagon.


Observations on the pancreatic islet tissue of young diabetic subjects.


Fluoroscopic pulmonary densiography.

Fluoroscopic pulmonary densiography.


A resectable form of multiple mesothelioma.


The topographic distribution of mineral dusts in some pneumoconiotic lungs.


Mass tuberculin patch testing of school children; a critical analysis of 125,000 cases.


Some statistical investigations in diabetes mellitus.


Utilization of glucose in normal and diabetic rabbits; effects of insulin, glucagon and glucose.


Insulin antagonists in blood of juvenile diabetics with arterial disease.


A preliminary report on the radiologic evaluation of trypsin in certain chronic chest diseases.


The treatment of acute infectious pericarditis and chronic constrictive pericarditis.


Incidence of relapses among patients treated with antibiotics and chemotherapy.


Group A beta hemolytic streptococci and rheumatic fever in Miami, Florida. I. Bacteriologic observations from October 1954 through May 1955.


Pre- and post-operative care of patients undergoing open cardiac surgery.


The importance of the unipolar morphologies in right bundle branch block.


The twenty-year course of chronic constrictive pericarditis with subsequent surgery.


Ambulatory oxygen therapy: oxygen inhalation at home and out-of-doors.


Carbohydrate metabolism and insulin sensitivity in the adrenalectomized dog; studies with C14 glucose.


The present situation of intrapleural pneumothorax and pneumoperitoneum in the treatment of pulmonary tuberculosis.


Clinical experience with ataractic therapy in tuberculous psychiatric patients.


Glucagon content of glucagon-insulin mixtures; estimation using coritsone-pretreated animals.


Ketogenic action of pituitary and adrenal hormones in pancreatectomized rats.


Pulmonary cystic disease: observations in cases treated by exploratory thoracotomy.


Minimal active tuberculosis: an increasingly difficult diagnosis.


Bronchopulmonary geotrichosis: a review with report of four cases.


Studies of 6-deoxy-6-fluoroglucose and insulin.


Intralobar pulmonary sequestration associated with anomalous pulmonary vessels: a nonentity.


Responsibility for tuberculosis case finding: changing the approach.


Actions of phenethylbiguanide and related compounds.


Diabetes in industry.

Diabetes in industry.


Mitral valve surgery: transventricular valvuloplasty and use of ivalon sponge pack for mitral insufficiency.


RECENT statistics on diabetes.

RECENT statistics on diabetes.


Clinical dyspnea and cardiopulmonary function studies.


Diuretic therapy.

Diuretic therapy.


Electrocardiogram of the month: retrograde conduction in complete heart block.


Varicosities of the pulmonary veins: a case report and survey of the literature.


The challenge of the medical and legal professions.


A case of spontaneous pneumothorax complicating gnathostomiasis.


Analysis of medical admissions to Mulago Hospital, 1957.


Duodenal ulcer amongst Africans in Nairobi.


Cavitation in tuberculosis; an operative approach.


James Christie and the cholera epidemics of East Africa.


Clinical evaluation of achromycin V in the treatment of trachoma.


Schistosoma mansoni infection in the West Nile district of Uganda. V. Host-parasite relationships.


Pneumonia in African children; a clinical, bacteriological and radiological study.


The Haw-Haw syndrome.

The Haw-Haw syndrome.


Outbreak of virus influenza of the Asian type in a semi-closed college community.


The spike and wave complex; a clinical correlation.


The relationship of epilepsy to breech delivery.


Studies on the flat electroencephalogram in man.


The electroencephalographic effects of methylpentynol.


The effect of largactil on the electroencephalographic response evoked potential to light stimulus in man.


The duration of human electroencephalographic arousal responses elicited by photic stimulation.


The electroencephalogram in kwashiorkor.


Seizure discharges effected by intravenously administered convulsant drugs; EEG and DC changes in cerebrum and cerebellum of the rabbit.


Effects of lesions of the rostral thalamus on brain waves and behavior in cats.


Electrocortical manifestations of epilepsy in monkey.


A variety of familial light sensitive epilepsy.


Tendon afferents in autogenetic inhibition in man.


Effects of a pyrimidine analog, 6-azauracil, on rat electroencephalogram and maze running ability.


Petit mal epilepsy and cortical epileptogenic foci.


Is it a tumor or is it eye movements? A method of greatly reducing eye movement artefacts in the frontal leads.


Electroencephalographic recording in simulated combat flight in a jet fighter plane; the pilot's level of consciousness.


An EEG artefact in palatal myoclonus.

An EEG artefact in palatal myoclonus.


Auditory analysis of the electroencephalogram: electroencephalophony.


A multielectrode lead for intracerebral recordings.


Reward delivery system for cats.

Reward delivery system for cats.


Automatic transport device for microelectrodes.


Elimination of C14-labeled thyroxine in the bile, urine and expired air of rats in altered thyroid states.


Thyroid function in experimental nephrotic syndrome.


Effect of thyroid imbalance on the detoxication of benzoic acid in the rat.


Thyroid epithelium in tissue cultures: observations on the morphology and functional capacities of embryo chick thyroids.


A direct influence of 5-hydroxytryptamine on the adrenal cortex.


Progestational activity of 17-alpha-methyl-19-nor-testosterone.


In vitro and in vivo metabolism of prednisolone: studies concerning its biological effectiveness.


A method of assay of antitumor activity using a rat mammary fibroadenoma.


Inhibition of mammary fibroadenoma of female rats by steroids of the androstane series.


An effect of corticotropin on urea formation in adrenalectomized-nephrectomized rats.


The mechanism of insulin resistance in the KL strain of mice: inactivation of insulin.


Effect of frequent housing changes and of muscular exercise on the thyroid gland of mice.


Potentiation of biological activities of steroids by carcinogenic hydrocarbons.


A method for the evaluation of adrenocortocotropic hormone suppressing action of corticoids.


Adrenal corticoid activities of 9 alpha-fluoro-11 beta, 16 alpha, 17 alpha, 21-tetrahydroxy-1, 4-pregnadiene-3, 20-dione.


Thyroxine excretion increase by cold exposure.


Effects of restricted food intake and growth hormone on rat liver proteins and nucleic acids.


Studies on the effect of storage on the purity of sodium iodide-I 131.


The anti-androgenic activity of a phenanthrene derivative in the chick.


Inhibition of thyroxine action by 3,3',5'-triiodothyronine.


Pathogenesis of pulmonary tuberculosis.

Pathogenesis of pulmonary tuberculosis.


Premarin in intraocular surgery; further studies.


Tissue tolerance of plastic resins; experimental study of their physical, chemical and histopathological reactions.


Choice of anesthetic for tonsillectomy.

Choice of anesthetic for tonsillectomy.


Some tumors of the neck; references to surgical procedures.


Studies on the mechanism of the female genital function.


Variations of the hysterosalpingogram in the fertile woman.


Fertility expectancy following prolonged extrascrotal residence of the testes.


Corelationship between vaginal cytology and endometrial histology in amenorrhea.


Progesterone and pregnanediol.

Progesterone and pregnanediol.


Estrogens.

Estrogens.


Gonadotropins.

Gonadotropins.


Evaluation of the role of the adrenal cortex in infertility.


The sick newborn.

The sick newborn.


Intestinal parasitism in a rural patient population.


The management of stress incontinence by general practitioners.


Pilonidal disease: management without excision.


Mucoviscidosis (cystic fibrosis of the pancreas).


Mortality survey in twenty-six years of general practice.


The results of desensitization in allergy to insect stings.


The management of antepartum bleeding.

The management of antepartum bleeding.


Prevention of sunburn and light allergy with methoxsalen.


Can the general practitioner do psychotherapy.


The familial pattern and treatment in the changing allergic state.


Medical auditing.

Medical auditing.


Practical and safe pain relief during parturition.


Present-day problems of staphylococcal infections.


Malabsorption syndromes.

Malabsorption syndromes.


New approach to narcotic addiction.

New approach to narcotic addiction.


Averting professional liability action.

Averting professional liability action.


What the new medical expense tax deduction means to the general practitioner.


Diagnostic considerations in patients with stroke.


Some current trends in problems of the aged.


Craniopharyngiomas in aged mental patients.


Management of elderly patients with fractures of the upper end of the femur.


Management of osteoporosis in the elderly patient. II.


Release program for geriatric patients at a state mental hospital.


A nutrition program for older people.

A nutrition program for older people.


Posthospital social planning for geriatric mental patients.


Multiple malignant neoplasms in a man aged 89 years; a clinicopathologic conference.


Strokes due to thrombosis of the internal carotid artery.


Mental confusion in elderly persons.

Mental confusion in elderly persons.


Mental disorders of advanced years.

Mental disorders of advanced years.


Radiological aspects of carotid artery syndrome.


An activity program for old persons in a sheltered living community.


Effect of dietary proteins on blood cholesterol levels of adults.


Absorption of vitamin B12 in the aged.

Absorption of vitamin B12 in the aged.


[Uricosuric action of 2-phenyl-5-bromo-1,3-indandione].


Extension service in a home for the aged.


Prolonged course of untreated gastric neoplasm; report of a case in a 70-year-old man.


Gallstone ileus in a 95-year-old woman; a case report with six-year follow-up studies.


Criteria for retirement.

Criteria for retirement.


Diagnostic problems in the elderly.

Diagnostic problems in the elderly.


Tronchin and Boerhaave.

Tronchin and Boerhaave.


Auto show aids hospital's building fund.


Hospital cost statistics. I.

Hospital cost statistics. I.


Factors which affect telling hospital cost story.


Self-insurance from the buyer's point of view. II.


A history of hospitals.

A history of hospitals.


Stress the employee in your employee handbook. II.


There is no time for complacency.

There is no time for complacency.


What is involved in a good training program.


The demise of the hand-wrapped sponge.

The demise of the hand-wrapped sponge.


The nursing shortage: a review of the literature and possible solutions. II.


The microwave oven in hospital food service.


Drug and solution control. II.

Drug and solution control. II.


Purchasing procedure and inventory control.


The impact of social change.

The impact of social change.


The veil in blackmail.

The veil in blackmail.


Office management: planning and control.


Patron Saints of Catholic hospitals.

Patron Saints of Catholic hospitals.


The M.R.L. and the hospital apostolate.

The M.R.L. and the hospital apostolate.


A dozen basic problems.

A dozen basic problems.


Medical education and the law.

Medical education and the law.


O.R. experience program aids professional student nurses.


The head nurse.

The head nurse.


Pharmacy human relations.

Pharmacy human relations.


What continuing education means.

What continuing education means.


Selecting and retaining dietary personnel.


Hospital uniforms.

Hospital uniforms.


Purchasing disposables; a survey.

Purchasing disposables; a survey.


Hospitals in the 49th state.

Hospitals in the 49th state.


A guide for designing and operating psychiatric units in general hospitals.


Blue Cross and insurance.

Blue Cross and insurance.


Oraganizing and operating a chronic disease unit in a general hospital.


The architect-administrator team: a fusing of talents.


Standard formula for tube feedings saves time and labor.


Giant in the basement. II. Only scientific tests can point way to built-in heating (and cooling) economy.


The future nurse: her place and preparation.


Health insurance and mental illness.

Health insurance and mental illness.


How does an administrator administrate.

How does an administrator administrate.


Getting the volunteer program off to a good start.


Physicians' private offices at hospitals.


Nursing-housekeeping: building peaceful coexistence.


How good is your housekeeping.

How good is your housekeeping.


ILLUMINATED table aids in O.R. linen repair.


11 VARIATIONS on a Lenten theme.

11 VARIATIONS on a Lenten theme.


How health needs of the aged are met in Colorado.


Staphylococcal pneumonia.

Staphylococcal pneumonia.


Advances in medical treatment of glaucoma.


The pathogenesis of peptic ulcer.

The pathogenesis of peptic ulcer.


A report on brain-damaged children.

A report on brain-damaged children.


Newer concepts of obesity.

Newer concepts of obesity.


Experience in the Peoria Work Classification Unit.


Alcaligenes faecalis; its systematic study.


Serum cholinesterase in liver disease.

Serum cholinesterase in liver disease.


Effect of graded doses of testosterone propionate on the adrenal cortex of young male rats.


Preliminary pharmacological investigations of total alkaloids of Lochnera rosea Reichb (rattanjot).


Effect of graded doses of testosterone propionate on the adrenal cortex of prepubertally castrated male mice.


Observations on the effect of chlorpromazine and promethazine on tissue respiration and succinic dehydrogenase activity of brain and liver of rats.


The superimposition of calorie restriction on protein deficiency; effects on liver, small intestine and pancreas of young albino rats.


Histochemical and histological studies in normal and aminopterin treated rats.


Effect of cadmium chloride on the response of the genital organs of gonadectomized male and female rats to homologous sex hormones.


Studies on lipid metabolism. II. Effect of high protein diets on the development of experimental atherosclerosis and the role played by glucose-cycloacetoacetate.


Effects of lesions in the limbic system on the affective behaviour and visceral responses in the monkeys and cats.


Effect of flow protein diets on the intermediary metabolism of hepatic ferritin.


Ultracentrifugal study of undiluted normal human serum.


Nitrogen balance studies in pregnant women in South India.


Epidemiological observations on the influenza epidemic in the rural areas of Singur, West Bengal, during June-August, 1957.


Nutritive value of proteins of green vegetables.


Epidemiology of 1957 influenza epidemic in Calcutta.


The geography of human disease.

The geography of human disease.


Industrial practice, Polynesian style.

Industrial practice, Polynesian style.


A new analgesic: clinical report.

A new analgesic: clinical report.


Acute gastro-enteritis in infants and young children with special reference to some etiological factors (analysis of 665 cases).


Treatment of acute diarrhoea.

Treatment of acute diarrhoea.


Industrial compensation aspects of heart disease.


Climbing up stairs.

Climbing up stairs.


Management and union health programs; the coordination of care and public understanding and acceptance of health services.


Emotional stress in dysmenorrhea.

Emotional stress in dysmenorrhea.


Hygienic lead standards.

Hygienic lead standards.


Clinical control of health in the storage battery industry.


The lead content of water from red-lead painted tanks.


Health control in the ceramic industry.

Health control in the ceramic industry.


An evaluation of blood lead analyses.

An evaluation of blood lead analyses.


Precautionary labeling of lead products.


Common errors in the diagnosis of plumbism.


A lawyer looks at lead.

A lawyer looks at lead.


Effects of season and temperature on childhood plumbism.


EDTA therapy in persons with excessive lead absorption from industrial exposure.


Lead poisoning in children and its therapy with EDTA.


Responses of human subjects to lead compounds; progress report on an experimental investigation of factors which influence the responses of human subjects to finely divided lead compounds in the atmosphere.


Oxidant plant damage from ozone-olefin reactions.


Application of microdiffusion of organic acids to air analysis.


The physiological response of guinea pigs to atmospheric pollutants.


The ascent of turbulent forced plumes in a calm atmosphere.


The behaviour of chimney plumes.

The behaviour of chimney plumes.


The colorimetric determination of sulfur oxides in atmosphere.


Atmospheric SO2 concentrations observed in Keihin industrial center and their relation to meteorological elements.


The technical provisions of the British Clean Air Act: regulations for Scotland.


The anesthesiologist looks at pediatric fluid problems.


The anesthetic management of head and face injuries.


Comparative Negro and white mortality during anesthesia, obstetrics and surgery.


Anileridine as an anesthetic agent.

Anileridine as an anesthetic agent.


Anesthetic management of patients with cardiovascular disease.


Pharmacologic hibernation in lung surgery for the tuberculous patient.


Contributions of the anesthesiologist to the medical profession.


Rates of transfer of Rb86, K42, K39, Cl36, Cl35, Na22, and Na23 across a blister surface on the forearm of normal man and patients with chronic congestive heart failure.


Comparative metabolism of strontium and calcium in man.


A versatile, high-contrast photoscanner for the localization of human tumors with radioisotopes.


A method for the determination of water intake of grazing sheep.


The determination of copper and zinc in biological material by activation analysis.


Micro-determination of zinc in blood and other tissues by neutron activation analysis.


Radio-iodine counting in unanesthetized mice.


An inexpensive metabolism apparatus for collecting CO2 excreta and blood from small experimental animals.


An apparatus for the intracavity administration of radioactive colloidal gold.


Effects of ionizing radiations on tissue mast cells.


Insecticide resistance in several strains of house flies in Japan.


Miyagawanella: psittacosis-lymphogranuloma group of viruses. VIII. Tetracycline and chlortetracycline treatment of goats perorally infected with goat pneumonitis virus in special reference to eradication of fecal virus.


Serologic and genetic relationships between Candida robusta and Saccharomyces cerevisiae.


Comparative studies on chromosomes among rat ascites hepatoma cells before and after the establishment of cell strains in tissue culture.


[Rehydration in the infant].

[Rehydration in the infant].


Antibody titer in allergic children given adenovirus vaccine.


Growth suppression in asthmatic children receiving prolonged therapy with prednisone and methylprednisolone.


Serial intracutaneous testing for bee and wasp sensitivity.


Serologic studies on favism.

Serologic studies on favism.


Oral prophylaxis against poison ivy dermatitis with aqua ivy tablets. I. A controlled experiment and preliminary clinical report.


The history and philosophy of occupational licensing legislation in the United States.


The dental laboratory viewpoint.

The dental laboratory viewpoint.


The judicial view of occupational licensure.


The policy of the American Dental Association on the licensure or registration of commercial dental laboratories and dental laboratory technicians.


Application of cost accounting principles in determination of fees for services.


Application of fee determination principles in case presentation to individual patients.


Application of fee determination principles in group purchase: role of state dental society.


Control of dental anxiety with mephenesin.


Operation: dental x-ray filtration.

Operation: dental x-ray filtration.


Dynamics of occlusion.

Dynamics of occlusion.


Effects of antihistaminic therapy on diphenylhydantoin sodium (dilantin) gingival hyperplasia.


The prognosis of asthma in infancy.

The prognosis of asthma in infancy.


Delayed hypersensitivity in mice.

Delayed hypersensitivity in mice.


Allergy to the pollen of the common sugar beet (Beta vulgaris).


Basic elements of a program for effective dental practice administration.


Reserpine effects and experimentally produced lesions of cardiovascular sensitization and eosinophilia.


Penicillinase in the treatment of allergic reactions to penicillin.


An analysis of root canal instruments.

An analysis of root canal instruments.


Measurement of periodontal disease prevalence.


Public health dentistry: its principles and approach to community programs.


J. HARVEY BLACK.

J. HARVEY BLACK.


Removal of stylet injected into soft tissue during block anesthesia.


AMERICAN Dental Association Specification No. 13 for self-curing repair resins (first revision, approved December 1958, effective January 1, 1959).


THE FRESHMAN dental student.

THE FRESHMAN dental student.


The posterior veneer crown with gold cusps.


Adding zest to foods.

Adding zest to foods.


Recent developments in food products.

Recent developments in food products.


Wholesomeness of irradiated foods.

Wholesomeness of irradiated foods.


Promising developments in food preservation.


Flavor, color, and ascorbic acid retention; comparison of electronic vs. conventional cooking of vegetables.


Nutritive value of commercial breads.

Nutritive value of commercial breads.


Composition of turkey meat. III. Essential amino acid composition.


Electronic oven speeds service of tasty hospital food.


Electronic cooking with paper service saves costs.


History of the American Therapeutic Society, 1947-1957.


Preliminary clinical observations on the use of a biguanide (DBI) as an oral hypoglycemic agent.


Attitudes.

Attitudes.


Trends in therapeutic research.

Trends in therapeutic research.


Radiation treatment of cancer.

Radiation treatment of cancer.


The definition and diagnosis of hypothyroidism.


A critique of the concept of sympathetic-parasympathetic antagonism.


Enhancement of sodium salicylate absorption and clinical effectiveness by mephenesin.


Drugs, doctors and directives.

Drugs, doctors and directives.


Arteriosclerosis obliterans; an epitome.


Alloy steel wire as suture material for open anastomoses of the large intestine.


Treatment of low-resistance syndromes.

Treatment of low-resistance syndromes.


A method for the study of peripheral arteriosclerosis.


Some aspects of hypothermia during anesthesia.


The use of radioisotopes in a community hospital.


PANEL discussion on problems in the diagnosis and management of cardiovascular disease.


Hal McCluney Davison; 1891-1958.

Hal McCluney Davison; 1891-1958.


Seymour DeWitt Ludlum; 1876-1956.

Seymour DeWitt Ludlum; 1876-1956.


Harold Guyon Trimble; 1896-1957.

Harold Guyon Trimble; 1896-1957.


Enhanced absorption of iron with use of a new hematinic agent.


Chronic cor pulmonale; its management; notes on the use of chlorothiazide (diuril).


Emotional problems of adult cancer patients.


Clinical study with a new hydrocholeretic drug and a new hydrocholeretic-antispasmodic combination.


Proliferative retinopathy in diabetes mellitus; review of eight hundred forty-seven cases.


Diabetes in a New England town. III. A comprehensive baseline study in Oxford, Mass.


Long-term anticoagulant therapy in coronary disease.


Use of nitrofurantoin in chronic and recurrent urinary tract infection in children.


Fractures of the tibial plateaus.

Fractures of the tibial plateaus.


Granular urethritis in women; survey of three hundred patients treated by cystoscopic fulguration.


Brine bath treatments for decubitus ulcers.


Echinococcus in man and dog in the same household in New York City.


Simple regional nerve block for surgery of the hand and forearm.


NORETHANDROLONE.

NORETHANDROLONE.


Iatrogenic stiff shoulders.

Iatrogenic stiff shoulders.


Resection of multiple metastatic pulmonary lesions of osteogenic sarcoma.


POLOXALKOL.

POLOXALKOL.


USE OF phenylbutazone (butazolidin) in acute superficial thrombophlebitis.


NASAL medication.

NASAL medication.


Diabetes mellitus complicated enterococcic meningitis.


Surgical treatment of diverticulitis of the colon.


Surgical management of ulcerative colitis.


Organization and operation of a poison control center.


Technique, hazards, and usefulness of percutaneous splenic portography.


Perinatal mortality in the North Carolina Memorial Hospital, 1952-1958.


D-Pantothenyl alcohol in management of paralytic ileus.


Urologic problems in rehabilitation of hemiplegic patients.


Discovery of typhoid carrier by sewage sampling.


Failure of penicillin in treatment of acute gonorrhea in American troops in Korea.


New instrument for biopsy of the cervix and endocervix.


Screening for diabetes by the glucose oxidase method.


Current status of therapy in bronchial asthma.


THE LEGAL scope of industrial nursing practice.


AMMONIA toxicity and hepatic coma.

AMMONIA toxicity and hepatic coma.


REPORT of the committee to study A.M.A. objectives and basic programs.


Tube feeding.

Tube feeding.


Life-table analysis of survival after cerebral thrombosis; ten-year experience.


Intravenous urography with renografin 60%; a report of more than 600 cases.


Bronchial asthma due to food allergy alone in ninety-five patients.


Heart disease screening in elementary school children.


Intravenous use of oxytocin (pitocin) for induction of labor.


Comparison of three methods of screening for pediatric heart disease.


Prevention of infection of urinary tract in presence of indwelling catheters; description of electromechanical valve to provide intermittent drainage of the bladder.


Amnesia-analgesia for the management of children too young to cooperate; further observations.


Safety closure caps; safety measure for prevention of accidental drug poisoning in children.


Ileal intussusception as result of intestinal intubation.


CHLOROTHIAZIDE (diuril).

CHLOROTHIAZIDE (diuril).


CHLOROTHIAZIDE sodium (lyovac diuril).

CHLOROTHIAZIDE sodium (lyovac diuril).


NORETHINDRONE (norlutin).

NORETHINDRONE (norlutin).


MEDICAL guide for physicians in determining fitness to drive a motor vehicle.


ABUSE of antibiotic lozenges.

ABUSE of antibiotic lozenges.


Oral cholangiography; a method of visualizing the nonvisualized gallbladder.


Bacteremia during parturition; prevention of subacute bacterial endocarditis.


Simplified screening test for cystic fibrosis of the pancreas.


Relation of fibrosis of the pancreas to fatty liver and/or cirrhosis; an analysis of one thousand consecutive autopsies.


Association of specific overt behavior pattern with blood and cardiovascular findings; blood cholesterol level, blood clotting time, incidence of arcus senilis, and clinical coronary artery disease.


Prolonged administration of chlorpromazine (thorazine) hydrochloride.


Fever of obscure origin; the value of abdominal exploration in diagnosis; report of seventy cases.


Diffuse pulmonary schistosomiasis; report of two cases proved by lung biopsy.


Control of intractable pain in advanced cancer by subarachnoid alcohol block.


Stomatitis and proctitis as manifestations of meprobamate idiosyncrasy.


PREVENTION and control of occupational dermatoses.


Aspiration of amniotic fluid of the perinate; new concept of an old disease.


Buccal and sublingual administration of heparin potassium (clarin); studies of plasma triglyceride lipolysis and heparin levels.


Respirator tracheotomy tube.

Respirator tracheotomy tube.


Prevention of injuries in college athletics.


Protecting the boxer.

Protecting the boxer.


Prevention and treatment of ski injuries.


Respiratory physiology and skin diving.

Respiratory physiology and skin diving.


Surgical treatment of injuries to ligaments of the knee.


Management of ankle injuries sustained in sports.


Degenerative arthritis of the lumbosacral joint; the end-space lesion.


Pathology of jaundice resulting from intrahepatic cholestasis.


Late results in osteochondrosis of capital epiphysis of femur (Legg-Calvé-Perthes disease).


Clinical aspects of jaundice resulting from intrahepatic obstruction.


Mechanisms of bile secretion.

Mechanisms of bile secretion.


Persistent subarachnoid-pleural space fistula; report of a case.


Blood dyscrasias associated with tolbutamide therapy.


Leg ulcer in rheumatoid arthritis.

Leg ulcer in rheumatoid arthritis.


ANTICOAGULANTS: a cooperative effort.

ANTICOAGULANTS: a cooperative effort.


MALPRACTICE: delay in using lipiodol dye x-ray technique with lipiodol.


Foreign medical graduates; a progress report.


History of the Section on Obstetrics and Gynecology of the American Medical Association.


The adolescent and the gynecologist.

The adolescent and the gynecologist.


Youth and crime; psychiatric factors.

Youth and crime; psychiatric factors.


Youth and crime; social factors.

Youth and crime; social factors.


Effective treatment of resistant staphylococci and infectious and serum hepatitis.


OSTEOPATHY and rehabilitation: a panel discussion.


Likenesses of women physicians on stamps.


Organization of a pediatric service in a Chilean saltpeter mine.


Basic principles of surgery.

Basic principles of surgery.


Clinical evaluation of plasma fibrinogen determination in cases of myocardial infarction.


Modern nursing in hospitals.

Modern nursing in hospitals.


Internal biliary fistulas.

Internal biliary fistulas.


The aging kidney: function, structure, and observations.


The rural clinics program of the Kirksville College of Osteopathy and Surgery. II. The Program in operation.


The immunization of dairy cattle against staphylococcal mastitis.


Radiation biology in veterinary education and research.


Effects of ambient temperatures on the brucellosis rapid plate-agglutination test.


Two cases of vascular surgery in the dog.


Microbiological and therapeutic aspects in calf enteritis.


Demodectic and sarcoptic mange of dogs successfully treated with aramite.


A congenital cyclopiantype malformation in lambs.


Chlorpromazine premedication with pentobarbital anesthesia in the rabbit.


Myxoma of the heart in a dog.

Myxoma of the heart in a dog.


The dietary control of recurrent chronic dermatitis in a cocker spaniel; a case report.


The practice of veterinary medicine in a changing world.


Ureterocolostomy for relief of urinary stenosis in the domestic cat.


The surgery of subcutaneous tumors in parakeets (Melopsittacus undulatus).


Closed-circuit halothane anesthesia in the dog; a report of 142 anesthetic periods.


Nephritis in a sheep; a case report.

Nephritis in a sheep; a case report.


Bovine respiratory infections. I. Psittacosis-lymphogranuloma venereum group of viruses as etiological agents.


Relationship of atrophic rhinitis and virus pig pneumonia to growth rate in swine.


Pattern of N15-excretion in man following administration of N15-labeled glycine.


Estrogenic activity in green forage crops and its effects on breeding ewes.


Pattern of N15-excretion in man following administration of N15-labeled L-phenylalanine.


Interpretation of urinary N15-excretion data following administration of an N15-labeled amino acid.


Effect of continuous cold exposure on nocturnal body temperatures of man.


Relationship between nonprotein sulfhydryl concentration of seminal fluid and motility of spermatozoa in man.


Effects of semistarvation and water deprivation on adrenal cortical function and corticosteroid metabolism.


Suppression of sweet sensitivity by potassium gymnemate.


Motility studies of isolated antral pouches before and after vagus denervation.


Effects of restraint on oxygen consumption of the cold exposed guinea pig.


Studies of positive radial acceleration on mice.


Strength of human metatarsal bones under repetitive loading.


Elastic characteristics of isolated segments of human aortas under dynamic conditions.


Fate of radioactive kryton (Kr85) introduced intravenously in man.


Measurement of blood flow in kidney and isolated segments of intestine.


Esophageal and pleural pressures in man, upright and supine.


Failure of manual respiration.

Failure of manual respiration.


Relationship of potassium and calcium to hypothermic ventricular fibrillation.


Physiologic, biochemical, immunologic and pathologic changes following ozone exposure.


Demonstration of aventilatory mass flow during ventilation and apnea in man.


Airway resistance measurement during any breathing pattern in man.


Effects of metabolism and anesthesia on pulmonary ventilation.


Alveolar plateau of the single breath nitrogen elimination curve in normal subjects.


Inhibition of carbonic anhydrase: its effect on carbon dioxide elimination by the lungs.


Mechanism of diuresis during negative pressure breathing.


Influence of abdominal muscles, mesenteric viscera and liver on respiratory mechanics.


Fluid volume redistribution and thoracic volume changes during recumbency.


A simple plastic arterial cannulation device which minimizes clotting.


An apparatus for rapid, constant-rate intravascular injection.


Use of triton X-100 as a hemolytic agent in the spectrophotometric measurement of blood O2 saturation.


A note on Alexander's method for indirect determination of blood pressure in the rat.


Techniques in Heidenhain pouch experiments.


The relation of the veterinarian to the feed industry.


A rapidly responding continuous oxygen consumption recorder.


An improved arteriovenous oxygen difference recorder.


A modified gas analyzer for students.

A modified gas analyzer for students.


Volume-pressure diagram of the lungs and transmural pressure of the airways.


Experimental thoracic duct fistula for conscious dogs.


A new method of calibrating the Müller-Franz respiration gas meter.


Serum glutamic-oxalacetic transaminase activity in human beings subjected to positive radial acceleratory force.


Coronary artery atherosclerosis as a factor in aircraft accident fatalities.


Increased plasma glutamic-oxalacetic transaminase activity in monkeys due to nonspecific stress effect.


Human ability and high performance flight.


Psychiatric disorders in military aviators.


Spatial disorientation in jet aircrews.

Spatial disorientation in jet aircrews.


Rehabilitation of the flyer following thoracotomy.


Vibration, buffeting and impact research.


Uptake of P32 in resting cells of Clostridium perfringens.


Plaque morphology of certain streptomycete phages.


Nutritional requirements of Chromobacterium violaceum.


Studies of the toxin of Clostridium botulinum. V. Prophylactic immunization of pheasants and ducks against avian botulism.


Isolation and maintenance of oral L forms of bacteria in liquid media.


Fluorescent labels for antibody proteins; application to bacterial identification.


Glucose dissimilation by Clostridium tetani.


A rapid membrane filter method for direct counts of microorganisms from small samples.


Oxidation of 2-deoxy-D-glucose to 2-deoxy-D-gluconic acid by extracts of pseudomonas aeruginosa.


Studies of streptococcal cell walls. III. The amino acids of the trypsin-treated cell wall.


Studies on mixed infections. IV. Role of bacterial endotoxin in combined infection with Brucella suis and Coxiella burnetii.


Studies on mixed infections. V. Effect of stressor compounds in combined infection with Brucella suis and Coxiella burnetii.


Study on the growth of Coxiella burnetii in the L strain mouse fibroblast and the chick fibroblast.


An electron microscope study of the disposition and fine structure of Mycobacterium lepraemurium in mouse spleen.


Alduronic acid metabolism by bacteria.

Alduronic acid metabolism by bacteria.


Production, purification, and characterization of synnematin.


Production of filterable particles by Cellvibrio gilvus.


Some cytological observations of Micrococcus lactilyticus.


Inactivation of the influenza virus by low voltage roentgen rays.


Supplementary growth promoting effect of 2-methyl-1,4-naphthoquinone of Lactobacillus bifidus var. pennsylvanicus.


Light emission from extracts of luminous fungi.


The accumulation of D-galactose against a concentration gradient by slices of rabbit kidney cortex.


Glyceride-glycerol precursors in the intestinal mucosa.


Phosphorylation of pyruvate by the pyruvate kinase reaction and reversal of glycolysis in a reconstructed system.


Biochemical studies on inositol. V. Purification and properties of the enzyme that cleaves inositol to D-glucuronic acid.


Enzymatic formation of high levels of 1,3-diphosphoglycerate from 3-phosphoglycerate; isolation and further metabolism.


On the mechanism of action of yeast endo-polygalacturonase on oligogalacturonides and their reduced and oxidized derivatives.


Phosphoglyceric acid mutase activity without added 2,3-diphosphoglycerate in preparations purified from wheat germ.


Cyclic glycerophosphate formation from the glycerolphosphatides.


Studies on the glucuronic acid pathway of glucose metabolism.


Labeling of glucose, ribose, and deoxyribose by 1- and 2-C14-glycine in regenerating rat liver.


Studies concerning the composition, distribution, and turnover of phosphorus in a phosphatido-peptide fraction from mammalian tissue.


Cholesterol biosynthesis in preparations of liver from normal, fasting, x-irradiated, cholesterol-fed, triton, or delta 4-cholesten-3-one-treated rats.


Biological aromatization of steroids.

Biological aromatization of steroids.


Catabolism in vitro of cholesterol. I. Oxidation of the terminal methyl groups of cholesterol to carbon dioxide by rat liver preparations.


Isolation of H3-cortisol from the urine of guinea pigs fed H3-cholesterol.


The manner of absorption of 3-beta-cholestanol and delta 4-cholestenone by the rat.


Studies on collagen. II. Properties of purified collagenase and its inhibition.


Tryptophan peroxidase-oxidase, histidase, and transaminase activity in the liver of the developing rat.


A rapid and sensitive spectrophotometric method for the assay of chymotrypsin.


The intracellular location of phosphoprotein phosphatase activity.


Isolation of an insulin-degrading enzyme from beef liver.


The proteins of bovine pancreatic juice. II. Rates of synthesis in vivo of the cationic proteins.


The partial purification and some physical properties of cathepsin C from beef spleen.


The purification and properties of beta-methylaspartase.


The isolation, crystallization, and properties of proteins for rabbit eye lens.


An omega-hydroxy-alpha-amino acid dehydrogenase of Neurospora crassa; partial purification and some properties.


Isolation of beta-aminoisobutyric acid from bulbs of Iris tingitana var. Wedgewood.


The metabolism of gamma-aminobutyric acid-4-C14 by intact rats.


Reversible inactivation of trypsin by anhydrous formic acid.


The metabolism of I 131-labeled iodine, thyroxine, and triiodothyronine in the mammary gland of the lactating rat.


The origin of purine and pyrimidine deoxyribose in Escherichia coli systems.


The origin of purine and pyrimidine deoxyribose in T6r+ bacteriophage.


The metabolism of pantothenic acid.

The metabolism of pantothenic acid.


Assay and distribution of bound forms of pantothenic acid.


Pyrroline-5-carboxylate reductase of Neurospora crassa; partial purification and some properties.


Reversible metabolic swelling of bacterial protoplasts.


Reduction of cytochrome oxidase by reduced diphosphopyridine nucleotide-cytochrome c reductase.


Oxidative phosphorylation in fractionated bacterial systems. I. Role of soluble factors.


Amine oxidases. XVII. Mode of action of 1-isonicotinyl-2-isopropylhydrazine on monoamine oxidase.


Dehydrogenase activity of the tissues in scurvy.


The effect of vitamin K1 on oxidative phosphorylation of rat liver mitochondria irradiated with ultraviolet light.


Studies on the structure of the vitreous body. VI. Biochemical changes during development.


Oxidative phosphorylation in mitochondria from aged rats.


The relative retention of strontium and calcium in human bone tissue.


Acetate metabolism in vivo; effect of refeeding.


Acetate metabolism in vitro; effect of refeeding.


Method for isolation of large quantities of human and canine cardiac myofibrils.


The fibrinogen molecule: its size, shape, and mode of polymerization. Improved electron micrographs of the shadow-cast bovine fibrinogen molecule have been obtained establishing its general morphology and dimensions in the dry state. It consists of a linear array of 3 nodules held together by a very thin thread which is estimated to have a diameter of from 8 to 15 A, though it is not clearly resolved. The two end nodules are alike but the center one is slightly smaller. Measurements of shadow lengths indicate that nodule diameters are in the range 50 to 70 A. The length of the dried molecule is 475 +/- 25 A. Adopting the molecular volume from previous physical chemical data and the general morphological features and length from electron microscopy, we calculate the diameters of the end nodules to be 65 A and the center one as 50 A. The model of the molecule so obtained is consistent with the electron microscopical observations and the data from physical chemistry. The intermediate polymers formed when fibrinogen is activated with thrombin were also examined and found to be end-to-end aggregates of altered fibrinogen molecules which shrink in length during the process. Intermediate polymer lengths are from 1000 to 5000 A. The nodular nature of fibrinogen, its shrinkage and end-to-end aggregation on polymerization permits us to deduce an explanation for the system of cross-bands previously observed in stained fibrin fibrils.


Heteromorphic change of adult fibroblasts by ribonucleoproteins. Cultures of subcutaneous areolar fibroblasts from adult rats, when confronted in vitro with microsomes from rat liver or kidney, are changed heteromorphically so as to resemble cultures of nervous tissue. Similar effects follow exposure to the deoxycholate-insoluble fraction of microsomes, and to purified RNA from rat liver or from yeast. An equivalent ribonucleoside mixture has no heteromorphic effect. The degree of heteromorphosis can be related quantitatively to the amount of RNA administered, up to a maximum of 150 gamma per slide, above which toxicity intervenes. Ribonuclease destroys in considerable degree the effectiveness of the active agents. Heteromorphosis cannot be induced in this adult tissue by a short exposure (1 to 3 hours) followed by removal to normal medium. A 24 hour exposure to microsome suspensions, however, is followed by partial change lasting for at least several days. Results are most clear cut when cultures of the explant type are maintained continuously in contact with the RNA-containing agents; nevertheless, cell suspensions exposed for 2 to 3 days to heteromorphic agents in suitable concentration appear to be permanently changed. Interspecies experiments between rat and mouse indicate that rat fibroblasts are more labile than mouse, and/or rat microsomes are more potent as agents of heteromorphosis. Mouse liver microsomes have no morphogenetic effect on homologous fibroblasts, but exert a slight action on rat fibroblasts. Rat microsomes have a growth-stimulating effect, but no heteromorphic action, on mouse fibroblasts. Purified protein from snake venom, which is highly active as a growth factor for avian nervous tissue, is growth-stimulating to rat fibroblasts but has no heteromorphic action on this material.


Cell fractionation of anterior pituitary glands from beef and pig. Fresh anterior pituitary glands from beef and pig were separated by differential centrifugation into subcellular fractions. Nuclei and debris were obtained at 700 g for 15 minutes, secretory granules at 7000 g for 20 minutes, mitochondria at 34,000 g for 15 minutes, and microsomes at 78,000 g for 3 hours. Electron micrographs were taken of the individual fractions. Each fraction was analyzed for nitrogen, pentosenucleic acid (PNA), and phospholipide. Beef and pig anterior lobes were quite similar in their intracellular composition as seen in the subcellular fractions. Succinic dehydrogenase was localized in mitochondria, while alkaline phosphatase was concentrated in the microsomes. A proteinase with pH optimum at 8.2 was exclusively localized. in microsomal and supernatant fractions. Acid phosphatase, acid ribonuclease, and acid proteinase were distributed among the subcellular fractions in another pattern, indicating the presence of a particle type distinct from mitochondria and microsomes. The distribution of cytoplasmic PNA paralleled that of alkaline phosphatase.


A cytochemical study on the pancreas of the guinea pig. IV. Chemical and metabolic investigation of the ribonucleoprotein particles. Five ribonucleoprotein (RNP) fractions were isolated from the postmitochondrial supernatant of the pancreas of the guinea pig. Two were obtained from the microsomes which, by deoxycholate (DOC) treatment, were subdivided into a DOC-soluble and a DOC-insoluble fraction. The latter was taken to represent attached RNP particles. Two other fractions obtained from the microsomal supernatant supposedly represent free RNP particles existing as such in the cytoplasm, while a third fraction resisted sedimentation for 20 hours at 105,000 g and is considered to be a soluble nucleoprotein. These fractions exhibited different RNA/protein ratios and also different RNA turnover patterns, as determined after in vivo labelling with adenine-8-C(14). However, little discernible differences could be detected in the nucleotide composition of the RNA moieties of these RNP fractions. Amino acid-"activating" enzymes were found to occur in the fraction containing the soluble nucleoproteins. The discussion focuses on the relationships between these fractions and protein synthesis in the pancreas, using data given in this and a previous paper, and data contained in the literature.


Electron microscopy of the tapetum lucidum of the cat. The fine structure of the tapetum of the cat eye has been investigated by electron microscopy. The tapetum is made up of modified choroidal cells, seen as polygonal plates grouped around penetrating blood vessels which terminate in the anastomosing capillary network of the choriocapillaris. The tapetal cells are rectangular in cross-section, set in regular brick-like rows, and attain a depth of some thirty-five cell layers in the central region. This number is gradually reduced peripherally, and is replaced at the margin of the tapetum by normal choroidal tissue. The individual cells are packed with long slender rods 0.1 micro by 4 to 5 micro. The rods are packed in groups and with their long axes oriented roughly parallel to the plane of the retinal surface. Each cell contains several such groups. Cells at the periphery or in the outer layers of the tapetum are frequently seen to contain both tapetal rods and melanin granules, the latter typical of the choroidal melanocytes. Also melanocyte granules may have intermediate shapes. These observations plus the similar density of the two inclusions lead to the belief that the tapetal rods may be melanin derivatives. A fibrous connective tissue layer lies between the tapetum and the retina. The subretinal capillary network, the choriocapillaris, rests on this layer and is covered by the basement membrane of the retinal epithelium. The cytoplasm of the retinal epithelium exhibits marked absorptive modifications where it comes in contact with the vessels of the choriocapillaris. This fibrous layer and the basement membrane of the retinal epithelium apparently comprise the structural elements of Bruch's membrane.


The absence of histone in the bacterium Escherichia coli. II. X-ray diffraction of nucleoprotein extract. X-ray diffraction photographs of a nucleoprotein preparation from Escherichia coli show the A-type pattern of crystalline deoxyribonucleic acid (DNA). This suggests that a large part of the DNA is free from protein. In higher organisms DNA does not exist in this form but is closely bound to protein.


The absence of histone in the bacterium Escherichia coli. I. Preparation and analysis of nucleoprotein extract. The deoxyribonucleic acid (DNA) from Escherichia coli has been isolated as an extract containing about 50 per cent by weight protein. The protein component differs both in composition and chemical behaviour from histone which occurs in combination with the DNA in most cells of higher organisms. Although this result suggests the absence of histone-like protein, it is not clear whether the bacterial protein found is naturally bound to the bacterial DNA in the cell or becomes attached to the DNA during the course of isolation.


The incorporation of leucine-C14 into microsomal particles and other subcellular components of the pea epicotyl. Incorporation of leucine-C(14) into subcellular fractions of the apical section of pea seedlings has been studied as a function of the length of incubation. The specific activity of the microsomes was higher than that of the supernatant for short but not for long incubations, in agreement with observations on other systems. In this developing tissue the nuclei and especially the mitochondria appear to incorporate amino acid very rapidly. An insoluble fraction of the microsome pellet, which is presumably a liponucleoprotein complex, was found to possess, after 1 hour of incubation, a specific activity much greater than that of the purified microsomal particles or the supernatant fraction. Ninety-eight per cent of the leucine-C(14) in the purified microsomal particles has been shown to possess bound amino groups, presumably in peptide linkages, by the DNP-end group method. These particles liberate but little peptide or protein of very high specific activity when they are destroyed by removal of Mg or by hydrolysis of RNA. Microsomal particles were fractionated into an RNA fraction and five protein fractions by means of density gradient centrifugation. By this method 95 per cent of the RNA can be separated from 90 per cent of the protein of the particle. Furthermore, the RNA fraction has been shown to contain very little protein of high specific activity. A particular protein fraction which contains the remaining 5 per cent of the RNA, possessed after 1 hour of incubation a specific activity 2 to 9 times higher than the protein of the other fractions.


The ingestion of proteins and colloidal materials by columnar absorptive cells of the small intestine in suckling rats and mice. Proteins and colloidal materials, administered orally to suckling rats and mice, were ingested by columnar absorptive cells of the jejunum and ileum, but not of the duodenum. Bovine gamma globulin and ovalbumin were identified in the apical cytoplasm by staining with fluorescent antibody; trypan blue, Evans blue, saccharated iron oxide, and colloidal gold were detected intracellularly by their color, specific staining, and appearance in the electron microscope. Each substance was segregated in membrane-enclosed vacuoles, apparently part of a system of potentially interconnecting vacuoles and tubules in the apical cytoplasm which is continuous in places with the apical cell membrane. We postulate that ingestion of foreign materials was accomplished by pinocytosis, that is, by invagination of the apical cell membrane to form vacuoles containing material from the intestinal lumen. Approximately 18 days after birth columnar absorptive cells lost the ability to ingest proteins and colloids, and no longer contained large vacuoles and numerous tubules. At this age rats and mice lose the ability to absorb antibodies from the intestine in an immunologically intact form, and we conclude that cellular ingestion is part of the mechanism of absorption of intact proteins in suckling animals. Particulate fat apparently is absorbed in both newborn and adult animals by micropinocytosis. Thus adult animals may not have lost the capacity for pinocytosis, but rather have become selective as to what substances provoke it. Cortisone acetate, administered subcutaneously to rats 8 to 10 days old alters the columnar absorptive cells within 72 hours so that they resemble the cells in adult animals and no longer ingest proteins.


Cytological studies of the nematocysts of Hydra. I. Desmonemes, isorhizas, cnidocils, and supporting structures. Entire hydras or tentacles were fixed in OsO(4) or in KMnO(4) and thereafter washed, dehydrated, and embedded in a methacrylate mixture. Ultrathin sections were cut on an experimental model, thermal expansion type ultramicrotome or on a Porter-Blume microtome. The sections were examined in an RCA electron microscope. Type EMU-2 D. "Squash preparations" for light microscopy, were made from the hydra mouth region and the attached tentacles. These were observed with an AO Baker interference microscope. In the mature organism, three of the four types of nematocysts normally found in hydra could be positively identified with the electron microscope. The desmonemes, the smallest type, have a dense matrix and a thin capsule. The two different types of mature isorhizas could not be distinguished with certainty. They are intermediate in size between the desmonemes and stenoteles and have a capsule with a dense matrix. The cnidocil, or triggering hair, which is composed of a dense core and a fibrillar sheath has nine supporting elements arranged in a semi-circle near its base. Twenty "supporting structures" are arranged around the nematocyst capsule and interconnections between the supporting elements and these latter structures have been observed. Development of the nematocysts involves an increase in density of the matrix. Spines can be seen in the interior of tubular structures within the capsules of the holotrichous isorhizas.


Cytological studies of the nematocysts of Hydra. II. The stenoteles. Entire hydras or tentacles were prepared for electron microscopy as described in the preceding paper. The stenotele capsule has been observed to be composed of an external membrane, a thick chitinous or keratin layer, and an inner membrane. A sac-like extension of the capsular wall into the capsule bears spines and stylets on its inner surface and evagination of this structure occurs on discharge. Profiles of tubular or membranous structures often are seen within the capsules of resting stenoteles. These structures are presumably related to the external filament. The spines often reveal a flattened aspect which suggests that at least some of them might more accurately be called "vanes." A cnidocil has been found to accompany each stenotele. This study revealed several aspects of the developmental stages of stenoteles: A vacuole is formed which is nearly surrounded by the nematocyte nucleus. The vacuole content changes in density and a capsular wall is formed at the periphery of the vacuole. Tubules differentiate from the capsular matrix, and spines and stylets develop somewhat later. An operculum is formed from the nematocyte cytoplasm.


Correlation of physical and biological properties of mouse mammary tumor agent. Biophysical procedures have been used to determine the size and structure of the biologically active agent responsible for the transmission, through milk, of mouse mammary adenocarcinoma. Filtration of milk from RIII high-breast-cancer mice through gradocol membranes with decreasing pore sizes indicated that a minimum of activity passed through intermediate pore sizes (100 to 160 mmicro). Filtrates through smaller pores were significantly active. Milk treated with small doses of deuteron irradiation produced more tumors than the control, unirradiated milk; larger doses indicated a particle size much less than 100 mmicro. Free diffusion experiments indicated that the activity was associated with particles of two different sizes. Altogether the data denoted the presence of a large agent about 100 mmicro in diameter and a small agent 20 to 30 mmicro in diameter or possibly smaller. Furthermore, the presence in the milk of an inhibitor 40 to 60 mmicro is indicated by the results of all three approaches. The complex nature of the milk agent disclosed by the physical measurements agrees with the picture of one of the structures revealed by electron microscopy as well as with seemingly conflicting measurements reported in the literature. The large agent defined by these indirect methods corresponds to the whole particle seen in the electron microscope and the small agent corresponds to its internal core or nucleoid. It is suggested that the nucleoid is essentially a nucleic acid which may, in the absence of the "inhibitor," retain its activity after being stripped of its outer membrane or sac.


Production of the milk agent in cultures of mouse mammary carcinoma. Thin sections of tissue cultures grown from tumors of the RIII high-breast-cancer strain mice were studied in the electron microscope. These tissues contain an abundance of particles whose morphology is consistent with biophysical measurement of the milk agent. These particles, found only extracellularly in our cultures, are formed at the cell membrane. The process of formation, as reconstructed from sections, appears to include a thickening and protrusion of the cell membrane which then evolves gradually into a dense sphere and separates from the cell in much the same manner as does influenza virus. The contents of the newly formed body are later rearranged to form a nucleoid within a membranous sac.


Mitochondrial swelling induced by glutathione. Reduced glutathione, in concentrations approximating those occurring in intact rat liver, causes swelling of rat liver mitochondria in vitro which is different in kinetics and extent from that yielded by L-thyroxine. The effect is also given by cysteine, which is more active, and reduced coenzyme A, but not by L-ascorbate, cystine, or oxidized glutathione. The optimum pH is 6.5, whereas thyroxine-induced swelling is optimal at pH 7.5. The GSH-induced swelling is not inhibited by DNP or dicumarol, nor by high concentrations of sucrose, serum albumin, or polyvinylpyrrolidone, in contrast to thyroxine-induced swelling. ATP inhibits the GSH swelling, but ADP and AMP are ineffective. Mn(-+) is a very potent inhibitor, but Mg(++) is ineffective. Ethylenediaminetetraacetate is also an effective inhibitor of GSH-induced swelling. The respiratory inhibitors amytal and antimycin A do not inhibit the swelling action of GSH, but cyanide does; these findings are consistent with the view that the oxidation-reduction state of the respiratory chain between cytochrome c and oxygen is a determinant of GSH-induced swelling. Reversal of GSH-induced swelling by osmotic means or by ATP in KCl media could not be observed. Large losses of nucleotides and protein occur during the swelling by GSH, suggesting that the action is irreversible. The characteristically drastic swelling action of GSH could be prevented if L-thyroxine was also present in the medium.


The swelling of rat liver mitochondria by thyroxine and its reversal. The in vitro swelling action of L-thyroxine on rat liver mitochondria as examined photometrically represents an acceleration of a process which the mitochondria are already inherently capable of undergoing spontaneously, as indicated by the identical kinetic characteristics and the extent of thyroxine-induced and spontaneous swelling, the nearly identical pH dependence, and the fact that sucrose has a specific inhibitory action on both types of swelling. However, thyroxine does not appear to be a "catalyst" or coenzyme since it does not decrease the temperature coefficient of spontaneous swelling. The temperature coefficient is very high, approximately 6.0 near 20 degrees . Aging of mitochondria at 0 degrees causes loss of thyroxine sensitivity which correlates closely with the loss of bound DPN from the mitochondria, but not with loss of activity of the respiratory chain or with the efficiency of oxidative phosphorylation. Tests with various respiratory chain inhibitors showed that the oxidation state of bound DPN may be a major determinant of thyroxine sensitivity; the oxidation state of the other respiratory carriers does not appear to influence sensitivity to thyroxine. These facts and other considerations suggest that a bound form of mitochondrial DPN is the "target" of the action of thyroxine. The thyroxine-induced swelling is not reversed by increasing the osmolar concentration of external sucrose, but can be "passively" or osmotically reversed by adding the high-particle weight solute polyvinylpyrrolidone. The mitochondrial membrane becomes more permeable to sucrose during the swelling reaction. On the other hand, thyroxine-induced swelling can be "actively" reversed by ATP in a medium of 0.15 M KCl or NaCl but not in a 0.30 M sucrose medium. The action of ATP is specific; ADP, Mn(++), and ethylenediaminetetraacetate are not active. It is concluded that sucrose is an inhibitor of the enzymatic relationship between oxidative phosphorylation and the contractility and permeability properties of the mitochondrial membrane. Occurrence of different types of mitochondrial swelling, the intracellular factors affecting the swelling and shrinking of mitochondria, as well as the physiological significance of thyroxine-induced swelling are discussed.


The origin and fate of annulate lamellae in maturing sand dollar eggs. Electron micrograph evidence is presented that the nuclear envelope of the mature ovum of Dendraster excentricus is implicated in a proliferation of what appear as nuclear envelope replicas in the cytoplasm. The proliferation is associated with intranuclear vesicles which apparently coalesce to form comparatively simple replicas of the nuclear envelope closely applied to the inside of the nuclear envelope. The envelope itself may become disorganized at the time when fully formed annulate lamellae appear on the cytoplasmic side and parallel with it. The concept of interconvertibility of general cytoplasmic vesicles with most of the membrane systems of the cytoplasm is presented. The structure of the annuli in the annulate lamellae is shown to include small spheres or vesicles of variable size embedded in a dense matrix. Dense particles which are about 150 A in diameter are often found closely associated with annulate lamellae in the cytoplasm. Similar structures in other echinoderm eggs are basophilic. In this species, unlike other published examples, the association apparently takes place in the cytoplasm only after the lamellae have separated from the nucleus. If 150 A particles are synthesized by annulate lamellae, as their close physical relationship suggests, then in this species at least the necessary synthetic mechanisms and specificity must reside in the structure of annulate lamellae.


Fine structure of Bacillus subtilis. I. Fixation. The fine structure of Bacillus subtilis has been studied by observing sections fixed in KMnO(4), OsO(4), or a combination of both. The majority of examinations were made in samples fixed in 2.0 per cent KMnO(4) in tap water. Samples were embedded in butyl methacrylate for sectioning. In general, KMnO(4) fixation appeared to provide much better definition of the boundaries of various structures than did OsO(4). With either type of fixation, however, the surface structure of the cell appeared to consist of two components: cell wall and cytoplasmic membrane. Each of these, in turn, was observed to have a double aspect. The cell wall appeared to be composed of an outer part, broad and light, and an inner part, thin and dense. The cytoplasmic membrane appeared (at times, under KMnO(4) fixation) as two thin lines. In cells fixed first with OsO(4) solution, and then refixed with a mixture of KMnO(4) and OsO(4) solutions, the features revealed were more or less a mixture of those revealed by each fixation alone. A homogeneous, smooth structure, lacking a vacuole-like space, was identified as the nuclear structure in a form relatively free of artifacts. Two unidentified structures were observed in the cytoplasm when B. subtilis was fixed with KMnO(4). One a tortuous, fine filamentous element associated with a narrow light space, was often found near the ends of cells, or attached to one end of the pre-spore. The other showed a special inner structure somewhat similar to cristae mitochondriales.


Fine structure of Bacillus subtilis. II. Sporulation progress. The sporulation process in Bacillus subtilis has been studied principally with KMnO(4) fixation, but also, for the purpose of comparison, with OsO(4) and mixtures of both fixatives. At a very early stage, the pre-spore is seen to consist of what seems to be the nuclear material and granular substance, surrounded by a layer of dense material destined to become the innermost layer of the spore coat. At a subsequent stage, a light interspace is observed that is destined to become the spore cortex. The mature spore shows a very complex structure. The spore coat is composed of three layers, the middle layer of which consisted of 5 to 8 lamellae of thin membranes and interspaces, both about 20 to 25 A thick. Between the inner layer of the spore coat and the spore cortex, a thin membrane with an affinity to the cortex can be observed. The spore coat is enclosed within two envelopes, one loosely surrounding the core, and the other adhering to it. The process of spore maturation has been studied in detail. Certain peculiar cellular structures have been observed that seemed to represent features of abnormal sporulation processes.


The effect of extended anaerobic treatments on the chromosomes of Vicia faba. The effects of extended anaerobic treatments on Vicia faba lateral root-tip chromosomes were determined. It was observed that aberrations resulted from these treatments, and that the frequency varied from root to root as well as from experiment to experiment. It was suggested that the inconsistency observed might be due to variation in the abilities of different roots to produce energy via fermentation routes. If this were true, an inhibition of fermentation would result in a more consistent aberration frequency. A fermentation inhibitor, NaF, was used in combination with extended anaerobic treatments. The observed frequency of aberrations after the combined treatments was generally higher and considerably less variable. Although other hypotheses might account for the NaF effect, the hypothesis most compatible with the evidence is that the effect is due to energy deprivation. The experimental results are discussed in terms of the aforementioned effect and in terms of three alternative hypotheses for the production of chromosomal aberrations as a consequence of a lack of energy. It is concluded that damage might result from a build-up of normal cellular compounds to abnormally high concentrations which would act directly or indirectly on the chromosomes, from the breakdown of DNA as an energy source, or simply as a result of the fact that the chromosome needs energy to remain intact.


Abnormal intranuclear and cytoplasmic formations associated with a chemically induced, transplantable chicken sarcoma. Thirty GRCH/15 tumors (a 1, 2, 5, 6-dibenzanthracene-induced chicken sarcoma) were examined in the light and the electron microscope. Associated with the sarcoma were two types of abnormal intranuclear lesions, one in the form of a vacuole, the other as an aggregate containing glycogen. In the electron microscope, one type of lesion observed showed an organized microfibrillar structure. Abnormal cytoplasmic formations occurred as massed clusters of thread-like or tubular material, which gave rise to small bodies with concentric shell structure; similar bodies were found associated with vacuoles.


Collagen formation by fibroblasts of the chick embryo dermis. This investigation has sought to determine the relation between collagen fiber and fibroblast during fibrogenesis. Toward this end the surfaces of chick fibroblasts grown under in vitro conditions have been examined with the electron microscope after fixation in OsO(4). Supplementary information has been obtained from thin sections of fibroblasts fixed in situ during phases of fiber production. The evidence provided by these studies and by various conditions of the experiments indicates that the unit fibrils of collagen form in close association with the cell surface. They were never observed within the cell. When these unit fibrils form in bundles it appears as though templates of some nature, possibly coinciding with stress fibers within the cell cortex, influence the polymerization of the fibrils out of material available at the cell surface. From here the fibrils and bundles of them are shed into the intercellular spaces and there grow to limited diameters by accretion of materials from the general milieu.


An electron microscope study of embryonic heart muscle cells grown in tissue cultures.


The use of novel supporting films for the electron microscopy of deoxyribosenucleic acid and other macromolecules.


The electron microscopy of human intestinal epithelium obtained with the Crosby intestinal biopsy capsule.


A new method of glass knife preparation for thin-section microtomy.


New observations on the alkaline glycerophosphatase reaction in the papilla foliata.


The phasic activity of the muscles of the lower extremity and the effect of tendon transfer.


The fine structure of the meiotic spindle of the crayfish.


Use of fine grain positive sheet film for electron microscopy.


Fracture of the intercondylar eminence of the tibia.


Surgery in the treatment of low-back pain and sciatica; a follow-up study.


The Bankart shoulder reconstruction; the use of pullout wires and other practical details.


The origin of the artery of the ligamentum teres femoris.


Recurrent congenital clubfoot; the role of the M. tibialis posterior in etiology and treatment.


Considerations on the surgical treatment of slipped epiphysis with special reference to nail fixation.


Hemangioma of the synovial membrane.

Hemangioma of the synovial membrane.


Spondylolysis; its anatomy and mechanism of development.


Xeroroentgenography; an evaluation of its use in diseases of the bone and joints of the extremities.


Biomechanical studies on the lumbar spine and pelvis.


Vertebral osteotomy for kyphosis, especially in Marie-Strumpell arthritis; a report on fifty cases.


Non-traumatic atlanto-occipital and atlanto-axial dislocation; a case report.


Results in the treatment of scoliosis with turnbuckle plaster cast correction and fusion.


Charcot disease of the spine; a report of two cases treated by spine fusion.


Congenital absence of the odontoid process of the axis; report of a case.


Osteoid osteoma; a fifteen-year follow-up of an untreated patient.


Ewing's sarcoma and reticulum-cell sarcoma of bone; with special reference to the histochemical demonstration of glycogen as an aid to differential diagnosis.


A metatarsus varus splint for the pre-walker.


Osteoblastoma of the scapula; a case report.


Prof. Dr. Jan Zahradnicek; 1882-1958.

Prof. Dr. Jan Zahradnicek; 1882-1958.


[Postoperative stenosis of the principal biliary tract caused by abnormal artery; Y-hepaticojejunostomy; radiological study of the functioning of the anastomosis].


Thyroid regulation of protein and nucleic acid accumulation in developing skeletal muscle of the chick embryo.


Reversible denaturation in the myosin adenosine triphosphatase system.


Regeneration of limb abnormalities after ultraviolet irradiation.


Cytochemical characterization of the granules in zona glomerulosa of the bovine adrenal gland.


The effect of temperature on potassium transfer in irradiated yeast.


The metabolic characteristics of yeast cells treated with fluoroacetic acid: evidence of the regulation of glucose oxidation by pH.


Experimentally altered structure related to function in the lobster axon with an extrapolation to molecular mechanisms in excitation.


Effects of certain enzymes on node of Ranvier excitability with observations on submicroscopic structure.


Sedimentability of microsomal nucleoprotein from rat liver homogenates in ionic media. I. Precipitation of pentose nucleoprotein by CaCl2.


Reticulo-endotheliosis.

Reticulo-endotheliosis.


The spark of life in medical missions.

The spark of life in medical missions.


Pott's-paraplegia.

Pott's-paraplegia.


Twenty years of yaws treatment amongst aboriginals in South Orissa.


Treatment of pancreatic cysts.

Treatment of pancreatic cysts.


Agranulocytic angina; with case reports.


A brief historical sketch of occupational medicine.


A case of rupture of the uterus in early pregnancy.


The values of limitations of periodic health examinations.


The chronically ill are employable.

The chronically ill are employable.


Pneumoconiosis.

Pneumoconiosis.


Chronic effects of ionizing radiation: industrial experience.


Industrial noise and hearing loss.

Industrial noise and hearing loss.


Beryllium disease.

Beryllium disease.


Emotional disorders, a problem in occupational medicine.


Economic poisons in relation to man's health.


Chronic lead and mercury poisoning: contemporary views on ancient occupational diseases.


The prevention of mental disorders.

The prevention of mental disorders.


Anxiety and the anxiety states.

Anxiety and the anxiety states.


The pressure, temperature and ion relations of myosin ATP-ase.


Psychoneuroses and their management in general practice.


The depressive illnesses: their diagnosis and treatment.


Ambulatory schizophrenia.

Ambulatory schizophrenia.


Depression, brain damage, and chronic illness of the aged; psychiatric diagnosis and treatment.


Delirium, a syndrome of cerebral insufficiency.


The use of modern pharmacologic agents in psychiatric disorders.


The challenge of the partial cure.

The challenge of the partial cure.


The psychosomatic concept, use and abuse.


Management and treatment of drug addiction.


A study of cornification in vaginal, buccal and urinary sediment smears.


Effects of intravenous infusions of dl-aldosterone acetate on sodium and potassium excretion in man.


Metabolism of progesterone-4-C14 by an arrhenoblastoma.


The uptake of P32 as a measure of cellular metabolism in the human thyroid.


The effect of triiodothyronine and thyroxine upon the rate of release of thyroid hormone in various thyroid states.


Assay of thyroid function in diabetes mellitus.


Changes in plasma levels of 17-hydroxycorticosteroids during the intravenous administration of adrenocorticotropin (ACTH). IV. Response to prolonged infusions of small amounts of ACTH.


Studies on adrenocortical function in obesity.


Pheochromocytoma in father and son: report of the eighth known affected kindred.


Treatment of a lingual goiter with triiodothyronine.


Inactivation of the antidiuretic activity of vasopressin during pregnancy: a report of a case.


Complete sex reversal: a case report.

Complete sex reversal: a case report.


Interference by copper in the determination of serum butanol-extractable iodine.


Plasma nonesterified fatty acids in hyperthyroid states.


Reaction of I-131 trace labeled human anti-Rho(D) with red cells.


Effects of exogenous adrenocorticotropic hormone (ACTH) upon pituitary ACTH concentration after prolonged cortisone treatment and stress.


On the rate of hydrocortisone clearance from plasma in pregnant women and in patients with Laennec's cirrhosis.


Studies on the relationship between glucose oxidation and intermediary metabolism. III. The influence of pyridine nucleotides on protein synthesis.


Myocardial response to acetyl strophanthidin in congestive heart failure; a study of electrolytes and carbohydrate substrates.


Early effects of thyrotropin on protein-bound iodine 131 and plasma iodide 131.


Effects of isoproterenol on peripheral venous tone and transmural right atrial pressure in man.


Studies on the mechanism of the lupus erythematosus (L.E.) phenomenon.


The influence of urinary ionic strength on phosphate pK2' and the determination of titratable acid.


Studies in Cushing's syndrome. III. Urinary 17-ketosteroids in patients with bilateral adrenal cortical hyperplasia.


The effect of the administration of sodium bicarbonate and ammonium chloride on the excretion and production of ammonia; the absence of alterations in the activity of renal ammonia-producing enzymes in the dog.


The role of pH gradient in the distribution of ammonia between blood and cerebrospinal fluid, brain and muscle.


Transcortin: a corticosteroid-binding protein of plasma.


Body iron exchange in man.

Body iron exchange in man.


Esophageal catheterization studies. I. The mechanism of swallowing in normal subjects with particular reference to the vestibule (esophago-gastric sphincter).


The metabolic fate of C14 labeled pentoses in man.


A critical review of human haemoglobin variants. I. Methods for separation and characterization.


The excretion of I-malic acid in relation to the tricarboxylic acid cycle in the kidney.


Studies on the isolation and characterization of the "rheumatoid factor".


The electrical potential difference generated by the large intestine: its relation to electrolyte and water transfer.


The fatty acids of human milk. II. Alterations produced by manipulation of caloric balance and exchange of dietary fats.


Some effects on blood coagulation of erythrocytes and other cells.


Renal function in burned patients and its relationship to morphological changes.


A technique for studying the action of antiseptics on bacteria in subcutaneous tissues, with special reference to chlorhexidine.


Laboratory infection with Toxoplasma.

Laboratory infection with Toxoplasma.


The biochemistry and an tribiotic sensitivity of the Klebsiellae.


Congenital pulmonary lymphangiectasis.

Congenital pulmonary lymphangiectasis.


The incidence found at necropsy of metastases to the sternum and iliac crest, with special reference to carcinoma of the lung.


The problems of histological diagnosis in baso-squamous cell carcinoma of the skin.


The colorimetric estimation of alpha-amino nitrogen in tissue fluids.


A method for the determination of tartratelabile, prostatic acid phosphatase in serum.


A micro method for detecting indol formation.


The normal range of the prothrombin time estimated by Quick's method.


The estimation of protein in the cerebrospinal fluid using the M.R.C. photometer.


David Nunes Nabarro.

David Nunes Nabarro.


Interview and test data in a diagnostic problem: a case report.


A substitute for the Feulgen staining technique.


The problem of psychosomatic specificity in chronic urticaria: a case report.


Effect of tradition on husband choice and role as wife: a case report.


The critical incident approach to the study of psychopathology.


Improving the measurement of clinical performance of medical students.


A suggested instrument for evaluating speech therapy with cerebral palsied adults.


Needs, values, perceptions and the nurse-patient relationship.


Effect of form-color incongruity on responses to inkblots.


Non-verbal communication of affect.

Non-verbal communication of affect.


The Hunter-Pascal concept formation test: an experimental approach to the measurement of cortical capacity.


Individual differences in response validity.


Prediction of first grade school achievement with the Bender Gestalt test and human figure drawings.


The sixteen personality factor test in clinical practice.


Construct validity of the Chicago Q-sort: frustration tolerance.


A validity study of the semantic differential technique.


Anagram-solving ability as an index of anxiety.


The relationship of sex and intelligence to choice of words: a normative study of verbal behavior.


Performance and verbal IQ in a group of sociopaths.


The influence of age on MMPI responses.

The influence of age on MMPI responses.


The response of prison inmates to seven new MMPI scales.


A study of performance differences on the Cattell infant intelligence scale between matched groups of organic and mongoloid subjects.


Some effects of socio-economic, age and sex factors on children's responses to the Rosenzweig picture-frustration study.


Perception of self and of normality in schizophrenics.


Preference for abstract versus concrete word meanings in schizophrenic and brain-damaged patients.


Attitudes of mothers of schizophrenic patients.


Multi-disciplinary views of the preparation of written clinical psychological reports. I. Spontaneous suggestions for content.


Perception of success or failure in pictures of others.


The relationship of the H-T-P to a sociometric evaluation of a group of primary grade school children in determining the degree of social acceptance.


Intelligence, and measures of inhibition and time sense.


The use of learning theory in the psychological treatment of children.


The cytoarchitecture of the lateral geniculate body in the cat in relation to the distribution of crossed and uncrossed optic fibers.


On the termination of the rubrobulbar fibers; experimental observations in the cat.


The arterial blood supply of the human spinal cord.


The development of subnucleus caudalis of the nucleus of the spinal tract of V.


Projection of the gracile and cuneate nuclei in Macaca mulatta: an experimental degeneration study.


Scatter radiation emanating from the patient during dental roentgenographic procedures.


Nitrogen content of zones distinguished by reflected light in enamel sections from unerupted third molars.


The effect of vitamin A deficiency upon experimental oral carcinogenesis.


The effect of pH on the antimicrobial activity of para-aminotoluene sulfonamide.


Half thickness of dentin to P 32 beta radiation.


A comparative histologic study of human periodontal structures utilizing fluorescence and visible light microscopy.


The effects of beta-aminopropionitrile upon the molar teeth of the rat.


A comparison of bone growth in normal and strontium-treated rats.


Radiation output of dental x-ray units.

Radiation output of dental x-ray units.


The polarized light appearances of human dental enamel.


The effect of castration on the submaxillary gland of Hunt-Hoppert caries-resistant and caries-susceptible rats.


The role of acidity of saliva in the nutrition of oral acidogens.


Differences in the morphology and size of the teeth of a caries-susceptible and a caries-resistant strain of rats.


Bacteriologic status of periapical tissue in 150 cases of infected pulpless teeth.


Antibacterial action of certain fluoride-containing dental restorative materials.


Comparative metabolism of blastocysts, extraembryonic membranes, and uterine endometrium of the mouse.


Fluoride content of human teeth from the Orient and the Canadian Arctic.


Electrophoretic analysis of chromatophorotropins in the dwarf crayfish, Cambarellus shufeldti.


Analysis of the organizer center in the early chick embryo. IV. Some differential enzyme activities of node center cells.


Studies on salivariadenectomized Hunt-Hoppert caries-resistant and caries-susceptible rats.


Orientation in paleotropical bats. I. Microchiroptera.


A method for producing fluoride-free salts and a fluoride-free diet.


Humoral immunity in lepidopterous larvae.


Effect of repeated additions of suboptimum amounts of a required vitamin of growth and acid production of lactobacilli.


The use of carbon dioxide in the treatment of postconcussion syndromes.


Cerebral hemispherectomy in infantile encephalopathy; indications for and results of with report of a case.


Emotions and epinephrine-norepinephrine metabolism.


Variability of tooth formation.

Variability of tooth formation.


The changing role of the radiologist.

The changing role of the radiologist.


Analysis of an anomalous oculodentofacial pattern in newborn rats produced by maternal hypervitaminosis A.


Alcoholism as a public health problem.

Alcoholism as a public health problem.


Development of coatings for application to teeth.


Lymphatic drainage of teeth in dogs demonstrated by radioactive colloidal gold.


Time course of parotid secretion in man.


Electron microscopy of developing enamel matrix in the Syrian hamster.


Streptococci in dental caries.

Streptococci in dental caries.


Stress and diabetes in forensic medicine.


Needle biopsy: a practical diagnostic tool bone marrow examination.


A method of measuring the adhesion of foodstuffs to tooth surfaces.


Trilafon (perphenazine) and meticorten (prednisone) as ancillary therapy in allergic conditions.


Nonfluorescent Microspora in tinea capitis.


Surgery in the aged.

Surgery in the aged.


Recent changes in the treatment of tuberculosis.


Practical points in the surgical management of congenital hemolytic anemia; report of two cases in siblings.


Clinical trial of a new laxative combination (stimulant-detergent type).


How can you prevent a suit.

How can you prevent a suit.


Krassilnikoviae: a new class of micro-organisms found in sea and ocean depths.


Nadsonia slovaca n.sp. isolated in Slovakia.


Salivary gland function in the rat. III. Protease and arginase activity of submaxillary glands and whole saliva.


Some physiological characters of yeasts from soils and allied habitats.


Investigation on streptomycin inhibitors with the aid of a streptomycin-dependent Vibrio comma.


The freezing points of bacterial cells in relation to halophilism.


A gene modifying the thiamine-requirement of strains of Neurospora crassa.


Amino acid requirements for formation of the reductive amination system in Bacillus subtilis.


Some applications of detergents to the study of the virus of foot-and-mouth disease.


Lysis of Vibrio costicolus by osmotic shock.


Some characters of Rhizobium strains from tropical legumes.


Some properties of a pectolytic soil Flavobacterium.


Some properties of an inhibitor of virus infection from leaves of raspberry.


Release of herpes virus from solitary HeLa cells.


A comparison of Nocardia asteroides and Nocardia brasiliensis.


Evidence for the occurrence of Permeases for tricarboxylic acid cycle intermediates in Pseudomonas aeruginosa.


Reversion of transduced antigenic characters in Salmonella typhimurium.


A new type of Acetobacter: Acetobacter acidophilum prov. sp.


Growth distribution in the light-growth response of Phycomyces. Elongation of sporangiophores marked with numerous starch grains was photographically recorded in the steady state and during the light-growth response when the rate is more than doubled. From these records the spatial distribution of growth within the cell's growth zone was derived. Stimulation by a single saturating flash of light speeds growth proportionally in all parts of the growing zone, maintaining the same pattern of growth distribution as in the steady state. This finding implies that light is absorbed and acts locally throughout the length of the cell's growth zone. Cohen and Delbrück's proposal of a partial spatial separation of light reception and growth is discussed.


Photo-reactions in Phycomyces; growth and tropic responses to the stimulation of narrow test areas. Sporangiophores of Phycomyces in stage IV b have been stimulated by parallel light in test areas 0.2 mm. wide. The growth responses to large stimuli are very large, owing probably to light scattered within the specimen. For medium stimuli the sensitive zone coincides with the growth response zone obtained previously and excludes the region of maximum stretch. Sustained stimulations were used to elicit tropic responses. The bends formed travel away from the sporangium at a speed equal to the growth speed. Thus they remain very close to the stimulus when this is held at a constant level relative to ground but separate from it for stimuli programmed differently. The existence of a protoplasmic structure, the "inner wall," with the following properties is postulated: it is attached to the lower, non-growing part of the sporangiophore and grows by addition above the sensitive zone. It neither stretches nor twists in the sensitive zone. It is the seat of the light receptors and gives growth and tropic responses. The cell wall follows its bends by elastic stretch.


The occurrence of polyol derivatives of cytidine diphosphate in micro-organisms.