Location and composition of spore mucopeptide in Bacillus species. Spore integuments of Bacillus coagulans were prepared containing nearly all the hexosamine and alpha, epsilon-diaminopimelic acid (DAP) present in intact spores. Subsequent autolytic action resulted in the destruction and removal of the residual cortical structure and "cortical membrane" leaving the appearance of the inner and outer spore coats unchanged in electron micrographs. Concurrently, all the hexosamine and DAP in the preparation was released mainly as non-diffusible mucopeptide containing alanine, glutamic acid, DAP, and all the glucosamine and muramic acid. Some diffusible peptides containing alanine, glutamic acid, and DAP were also present but there was little protein or carbohydrate. Lysozyme digestion of integument preparations from heated spores of Bacillus 636, B. subtilis, B. coagulans, and B. stearothermophilus specifically removed the residual cortex and cortical membrane with the release of the mucopeptide. In B. cereus T, only the residual cortex and part of the mucopeptide were solubilized by lysozyme. The effect of several reagents and enzymes upon the appearance and removal of hexosamine from B. coagul ans spore integuments is reported. The results show that spore mucopeptide is mainly located in the residual cortex and cortical membrane and suggest that these structures consist essentially of mucopeptide. The implications of these results in relation to the "contractile cortex" theory of heat resistance in spores are discussed.


Hepatic blood flow in patients with tumors of the liver.


The composition and structure of bacterial spores. The composition of the insoluble "integuments" and soluble "contents" fractions of spores of four Bacillus species of widely differing heat resistance were compared. Electron microscopy of thin sections was also used to determine and compare the morphological structures in the integument preparations. The soluble fractions of the thermophiles, B. coagulans and B. stearothermophilus, had a higher content of hexose and dipicolinic acid. The hexose content of both fractions of the four species was related to heat resistance. Integument fractions consisted chiefly of protein together with variable amounts of the mucopeptide constituents, alpha, epsilon-diaminopimelic acid (DAP) and hexosamine. In the thermophiles the DAP and hexosamine were found chiefly in the insoluble integuments fractions, while in B. cereus and B. subtilis most of this material was soluble. Integument preparations, containing mainly protein with little mucopeptide, consisted chiefly of outer and inner spore coats, while preparations having more mucopeptide contained also residual cortical material and a cortical membrane (possibly the germ cell wall). The results suggest that spore integuments consist of mainly proteinaceous outer and inner coats together with variable amounts of residual cortex and cortical membrane which contain the mucopeptide material.


Carcinoma of the prostate.

Carcinoma of the prostate.


Effect of previous homograft on passive transfer of delayed allergy.


Sclerema neonatorum--a sign, not a disease.


The effect of x-ray treatment on leukocyte alkaline phosphatase in cancer patients.


The role of the industrial nurse without immediate medical supervision.


Adolescent gynecology.

Adolescent gynecology.


The effects of physique and intrafamily tension on self-concepts in adolescent males.


The effects of smoking on the CFF threshold.


Cystic fibrosis of the pancreas in a young adult. Report of the case of a fourteen-year-old boy with pulmonary manifestations and subsequent exploratory thoracotomy.


Infantile entropion in sheep.

Infantile entropion in sheep.


Does "theoretical orientation" influence ratings of "warmth-acceptance"?


Value of oral potassium salts in differentiation of functional and organic T wave changes.


Noninfarctional QS II, III, AVF complexes (etc.).


The incomplete left bundle branch block.


The critical role of hypoxemia in the dyspnea of chronic pulmonary disease.


Influence of dietary potassium and sodium on cesium-137 retention in rats.


Electron microscopic study of adipose tissue (fat organs) with special reference to the transport of lipids between blood and fat cells.


Vitamin D3 inhibition of radiocalcium binding by chick intestinal homogenates.


A clinical appraisal of a pulmonary-function unit. A study of 100 consecutive patients.


Lung volume and respiratory muscle power in hyperthyroidism.


Human cardiopulmonary effects of doxapram, a respiratory stimulant.


Partial anomalous pulmonary venous drainage associated with mitral stenosis with an intact atrial septum. A distinctive hemodynamic syndrome.


Left atrial puncture in patients with rheumatic mitral valvular disease.


The diagnosis of atrial myxoma.

The diagnosis of atrial myxoma.


May-Hegglin anomaly. Hereditary affection of granulocytes and platelets.


Studies in infantile gastro-enteritis.

Studies in infantile gastro-enteritis.


The value of serologic tests in tuberculosis of children.


Review and follow-up of empyemas in 134 infants and children.


Analysis of some types of vocalization in the newborn and in early infancy.


Steroid therapy in acute, life-threatening infections.


The spread of excitation among neurons in the heart ganglion of the stomatopod, Squillia oratoria. Neurons in the heart ganglion of the mantis shrimp (a stomatopod crustacean) are functionally tightly linked together. The extracellular action potential from the whole trunk very often shows a complex form, but the response is all-or-none to the applied stimulus, indicating that the excitation in one neuron spreads very rapidly to all others. Application of isotonic MgCl(2) solution or repetitive stimulation sometimes separates the spike into its components. The resting potential of the soma membrane is 50 to 60 mv. External stimulation elicits a spike of 60 to 80 mv amplitude with a step on its rising phase. Hyperpolarization reveals one more inflection on the rising phase. These inflections divide the soma action potential into three parts, A(1), A(2), and B spikes in that order from the foot. The B spike disappears on increasing the hyperpolarization, but A(1) and A(2) remain, indicating that B originates from the soma membrane, whereas A(1) and A(2) originate from the two axons of the bipolar cell. Thus the impulse invades the soma from two directions, one from the stimulated side, the other from the other side via the "parallel axons" and the "side-connections;" the latter are presumed to interconnect the axons. When the parallel axons are cut, conduction takes place across the soma with a greatly reduced safety factor and a prolonged conduction time. Neuron-to-neuron transmission takes place in either direction.


Origins of diabetes mellitus as suggested by its epidemiology.


Diphasic seasonal variation of the serum protein-bound iodine level.


Embryonal hepatoma in Japan: pathological study on 19 cases of hepatic carcinoma in infancy and childhood.


Congenital malformations in the offspring of alloxan-diabetic mice.


Effect of magnesium and calcium ions on the fluorescence of the protonated ring of adenine, adenosine, adenosine 5'-phosphate, adenosine diphosphate, and adenosine triphosphate.


Fluorescence of magnesium-, calcium-, and zinc-8-quinolinol complexes.


Syntheses and antimicrobial activity of 5-alkyl-2-thiouracil derivatives.


Episome-mediated transfer of drug resistance in Enterobacteriaceae. V. Spontaneous segregation and recombination of resistance factors in Salmonella typhimurium. Watanabe, Tsutomu (Keio University, Tokyo, Japan) and Keong W. Lyang. Episomemediated transfer of drug resistance in Enterobacteriaceae. V. Spontaneous segregation and recombination of resistance factors in Salmonella typhimurium. J. Bacteriol. 84:422-430. 1962.-It was found that spontaneous segregation of the transmissible multiple drug resistance [resistance to streptomycin (Sm), chloramphenicol (Cm), tetracycline (TC), and sulfonamide (Su)] takes place so frequently in Salmonella typhimurium strain LT-2 (Su, Sm, Cm, Tc) as to allow a clone analysis of the segregation of resistance factors with replica plating. Su-, Sm-, and Cm- resistance factors together were spotaneously lost most frequently, whereas the spontaneous loss of Tc-resistance factor alone was rather infrequent. The complete loss of the resistance factors was also noted with low frequencies. The mechanism of the spontaneous segregation of the resistance factors was assumed to be due to either genetic exchange between the resistance factors and host genome or incomplete replication of the transmissible resistance factors (composed of resistance factors and resistance-transfer factor). In relation to the mechanism of spontaneous segregation of the transmissible resistance factors, circular models of the transmissible resistance factors are presented. Four-drug-resistant strains were produced by transferring segregant types of transmissible resistance factors (Su, Sm, Cm) and (Tc) to the strains with (Tc) and (Su, Sm, Cm), respectively. In these four-drug-resistant strains, the two types of transmissible resistance factors were found to be in two different states; in one state the two types of transmissible resistance factors exist in the same cells independently of each other, and in the other state a transmissible resistance factor, which was produced as a result of recombination of the two types of transmissible resistance factors, is present. Two unusual strains of LT-2 with Su-, Sm-, and Cm-resistance factors and with four resistance factors were found. These strains could not transfer their resistance factors to Escherichia coli K-12 by conjugation. Their resistance factors were spontaneously segregated as frequently as those of LT-2 (Su, Sm, Cm) and LT-2 (Su, Sm, Cm, Tc), and the transfer of (Tc) to strain LT-2 with nontransmissible Su-, Sm-, and Cm-resistance factors gave rise to two types of clones; one could transfer the four resistance factors as a unit to K-12 by conjugation, and another could transfer only (Tc) and frequently segregated two types of clones; one had (Tc) and another had nontransmissible Su, Sm-, and Cm-resistance factors. From these findings, the unusual strains with nontransmissible resistance factors are assumed to have a "defective" resistance-transfer factor.


Infective heredity of multiple drug resistance in bacteria.


Synthesis of poliovirus-specific proteins in HeLa cells.


Serological analysis of supernatant liquids of cultures of El Tor vibrios. Watanabe, Y. (406th Medical General Laboratory, U.S. Army Medical Center, Japan) and O. Felsenfeld. Serological analysis of supernatant liquids of cultures of El Tor vibrios. J. Bacteriol. 85:31-36. 1963.-Supernatant liquids of cultures of El Tor vibrios were analyzed serologically by applying the Ouchterlony agar diffusion technique. There are at least three different water-soluble antigenic components: thermolabile and exotoxin-like, thermolabile-bacterial, and thermostable-bacterial. All rabbit sera containing antibody(s) against the thermolabile exotoxin-like antigen(s) neutralized the lethal and hemolytic activities of the supernatant liquids of the cultures. These antibodies behave differently when absorbed with bacterial cells. The antihemolytic activity was not absorbed, whereas the antilethal was partially absorbed. The possibility of the existence of a nonactive toxin(s), which can stimulate production of antibodies against the lethal and hemolytic principles in the rabbit, was indicated.


Hemorrhage and shock in obstetrics.

Hemorrhage and shock in obstetrics.


Triglyceride metabolism in malignant disease and liver disease.


Growth rate, food and calorie consumption of laboratory cats.


Protein malnutrition and albumin breakdown.


A comparison of the incidence of jaundice between two premature baby units.


The absorption and retention of nitrogen from leaf protein by infants recovering from malnutrition.


The assessment of marginal protein malnutrition.


The partition of nitrogen in the urine of malnourished Jamaican infants.


Illegitimacy in Trinidad and Tobago.

Illegitimacy in Trinidad and Tobago.


Thyroid tissue and some of its properties in the hagfish, myxine glutinosa.


Electrical responses in decapod crustacean visual systems.


Observations on the metabolism of folic acid in pernicious anaemia.


Familial juvenile pernicious anaemia: a study of the hereditary basis of pernicious anaemia.


Attachment of Fluotec vaporizer to Boyle's apparatus.


Guided blind endotracheal intubation. For patients with deformities of the upper airway.


Insect control by radiation sterilization in Australia.


Rupture of uterus in late pregnancy. Changing concepts based upon studies of 50 cases.


Workmen's compensation laws. Fundamental philosophy and evolution.


New approaches to teaching will come.

New approaches to teaching will come.


Fallout radiation hazard to hospitals.

Fallout radiation hazard to hospitals.


Reduction of fallout radiation hazards in health installations. The purpose of this paper is to provide guidance for Canadian hospital medical directors in planning the provision of protection for their patients and staff against gamma radiation hazard from nuclear war. The implications of the distribution of fallout in Canada are that the probability of exposures in excess of 600 r in the period "96 hours after fallout" is high in Southern Ontario and Quebec but low in the western provinces and in the North. All hospitals should have a shielding capacity; for many, this will entail structural alterations. The aim would be to provide a protective factor of 100 or better, together with necessary standards of habitability. The engineering significance of the recommendations is discussed.


Reduction of fallout radiation hazards.

Reduction of fallout radiation hazards.


The role of surgery in the treatment of the rheumatoid hand.


Relationship between respiratory syncytial virus and Newcastle disease-parainfluenza group.


Changes in the morphology of Mycobacterium leprae in patients under treatment.


Congenital tracheo-oesophageal fistula in association with oesophageal atresia.


The fine structure of influenza A, B and C viruses.


The techniques used in assaying antibiotics in the clinical laboratory.


Mental rehabilitation at St. Wulstan's.

Mental rehabilitation at St. Wulstan's.


Disease factors complicating clinical appraisals of nutritional status.


Community care of the mental patient.

Community care of the mental patient.


Fifty years of Ramstedt's operation.

Fifty years of Ramstedt's operation.


Ten year follow-up on schizophrenic twins, one lobotomized.


Unrecognized depression, an illness in which the psychiatric background often goes unrecognized.


Islet-cell adenoma as a cause of juvenile hyperinsulinism in a four-year-old boy.


Incidence and current management of post-thyroidectomy hypoparathyroidism. Histologic evidence of rejection of neonatal aortic pedicle parathyroid gland homotransplants.


Blunt abdominal trauma.

Blunt abdominal trauma.


The role of neutralising antibody in immunity of the mouse to herpes simplex virus inoculated intracerebrally.


Pulmonary infection of adult white mice with the TE 55 strain of trachoma virus.


The reaction of mouse foot-pads to intradermal injection of trachoma virus.


A concentration and staining technique for diagnosing equine piroplasmosis.


The medical treatment of ulcerative colitis.


Treatment of carcinoma of the head and neck with AB-132 and radiation.


A correlation of clinical observations to in vitro sensitivity test for cancer chemotherapy.


Preoperative anticancer chemotherapy. Preliminary report.


Is tissue histamine formation necessary in cat, dog and man?


Cytopathic effect of infectious laryngotracheitis virus in cultures of chicken embryo kidney cells.


Urinary excretion of free histamine in guineapigs after oral histidine.


Intranuclear filaments associated with infectious laryngotracheitis virus.


Seminal vitamin B12 and sterility.

Seminal vitamin B12 and sterility.


A case of fibro-osteoma of mandible.

A case of fibro-osteoma of mandible.


Teaching mental health concepts in the law school.


A digital dosemeter for use in x-ray therapy.


Gastric exfoliative cytology. A report on 300 cases.


Increased urinary porphobilinogen and uroporphyrin after administration of stilboestrol in a case of latent porphyria.


Recent studies of the urobilin problem.

Recent studies of the urobilin problem.


The genetics and clinical significance of photogenic cerebral electrical abnormalities, myoclonus, and seizures.


On haemoglobin degradation in the newborn.


The micro-determination of blood glucose.


Serum calcium determination with 1,2-diaminocyclohexane-N-tetra-acetate.


A new method for microanalysis of blood galactose.


Bilirubin metabolism in disease.

Bilirubin metabolism in disease.


Neonatal jaundice.

Neonatal jaundice.


The absorption of bilirubin by erythrocytes.


Sterilizing techniques with ethylene oxide.


The structure of the capsid of GAL virus.


Electron microscopic particle counts on herpes virus using the phosphotungstate negative staining technique.


Electron-microgrophic particle counts of phosphotungstate-sprayed virus.


Epidemiology of the month.

Epidemiology of the month.


Sources of verbalizations of psychotherapists about patients.


Meclozine ("ancoloxin") and foetal abnormalities. Preliminary report by the Epidemic Observation Unit of the College of General Practitioners.


Protection after exposure to measles by attenuated vaccine without gamma-globulin.


Advantages of thre-phase spot-film radiography.


Involvement of RNA in the synthesis of proteins. We can now have considerable confidence that the broad features of protein synthesis are understood. The involvement of RNA is very much more complicated than was imagined in 1953. There is not one functional RNA. Instead, protein synthesis demands the ordered interaction of three classes of RNA-ribosomal, soluble, and messenger. Many important questions, however, remain unanswered. For instance, there is no theoretical framework for the ribosomal subunits, nor for that matter, do we understand the functional significance of ribosomal RNA. Most satisfying is the realization that all the steps in protein replication will be shown to involve well-understood chemical forces. As yet we do not know all the details. For example, are the DNA base pairs involved in messenger RNA selection of the corresponding amino-acyl-sRNA? With luck, this will soon be known. We can thus have every expectation that future progress in understanding selective protein synthesis (and its consequences for embryology) will have a similarly well-defined and, when understood, easy-to-comprehend chemical basis (62).


Topical nitrogen mustard in cutaneous lymphosarcoma (mycosis fungoides).


The key to survival.

The key to survival.


Effect of various penicillin compounds on haemagglutination of penicillin-coated erythrocytes.


Problems involved in dialyzing low concentrations of inorganic pyrophosphate.


Isolated cilia from Tetrahymena pyriformis.


Late results in vaginal hysterectomy.

Late results in vaginal hysterectomy.


Antiglobulins in normal serum. I. Characterization of two antiglobulins in normal rabbit sera.


The handfoot syndrome in sickle-cell disease in young children.


Pulmonary biopsy.

Pulmonary biopsy.


Swelling and dysfunction of the upper limb following radical mastectomy.


Supervoltage radiation therapy in advanced cancer of the urinary bladder.


Historical document, 1764. An account of what appeared on opening the body of an asthmatic person.


Children with defective hearing.

Children with defective hearing.


Rotascanography.

Rotascanography.


The absorption and excretion of castor oil in man.


The morphology and lipid composition of the erythrocytes in normal and essential-fatty-acid-deficient rats.


Observations on physiological deadspace during intermittent positive pressure respiration.


Observations on the dynamic lung compliance of patients with respiratory weakness receiving intermittent positive pressure respiration.


The action of trimetaphan on the vascular distensibility of the hand.


Observations on the ethical responsibility of the scientist.


Ear piercing for adornment.

Ear piercing for adornment.


Relapse during treatment of pernicious anaemia with refined liver extract.


Depressions in disguise.

Depressions in disguise.


Benzpyrene hydroxylase activity in the gastrointestinal tract.


Looking and listening in clinical work.

Looking and listening in clinical work.


The general practitioner and the third dimension.


Skin pH and verruca: a case history.

Skin pH and verruca: a case history.


Mental and emotional disorders in general practice.


Wound healing. Biochemical methods for observation of the cellular and intercellular phases.


A study of the 'reactive' sulphydryl groups of adenosine 5'-triphosphate-creatine phosphotransferase.


A factor in the serum of tumour-bearing rats which is deleterious to cells in tissue culture.


A fatal case of erythema multiforme exudativum (Stevens-Johnson's syndrome) following therapy with dilantin.


Fecal solids excreted by young men following the ingestion of dairy foods.


Effects of certain compounds on experimental muscular dystrophy.


'Cross-protection' method as a means of differentiating receptors.


Resection of the duodenum for extensive leiomyosarcoma.


Two methods for testing serial memorization.


Current trends in the surgical treatment of diverticulitis of the sigmoid colon.


Management of asthma-allergic aspects.

Management of asthma-allergic aspects.


Unreduced Colles fractures.

Unreduced Colles fractures.


Mitchell's operation for hallux valgus.

Mitchell's operation for hallux valgus.


Role of calcium in contractile excitation of vascular smooth muscle by epinephrine and potassium.


Sedation threshold, autonomic lability and the excitation-inhibition theory of personality. II. The mecholyl test.


Psychiatric social work.

Psychiatric social work.


The poetzl phenomenon re-examined experimentally.


Smooth muscle relaxation with a uracil compound (SC 4959).


The metabolism of C14 2-PAM in the isolated perfused rat liver. III. 1-Methyl-2-cyanopyridinium ion.


The metabolism of C-14-2-PAM in the isolated perfused rat liver. II. 2-O-conjugate pyridinium ion.


The metabolism of C-14-2-PAM in the isolated perfused rat liver.


Treatment of poisoning due to alkylphosphate cholinesterase inhibitors.


Supplementary juice for infants.

Supplementary juice for infants.


Lung and pleural changes accompanying distant and systemic pathology.


A survey of house officer attitudes toward physical medicine and rehabilitation.


Special series on medical education in Scotland, VIII. A summing up.


Cardiotoxic effects of antimony dimercaptosuccinate in schistosomiasis with special reference to coexistent hepatic dysfunction.


The biological disposition of morphine and its surrogates.


The development of new drugs.

The development of new drugs.


The halfway house; how it serves as a pathway agency for the psychiatric patient.


The special contributions of a hospital halfway house.


Use of methohexital sodium in ECT.

Use of methohexital sodium in ECT.


Exfoliative cytology, early carcinoma of the cervix, pregnancy and fertility.


Finding the "hidden positive" in tuberculosis eradication programs. The role of the sensitive trisodium phosphate-benzalkonium (zephiran) culture technique.


Differentiation of mycobacteria by their effect on tween 80.


Two varieties of Mycobacterium kansasii with different clinical significance.


Drugs used in the treatment of the alcoholic.


Effects of intracarotid injection of hypertonic saline on spinal reflex excitability.


Coronary inflow and outflow measurement technique in dogs with thorax intact.


Nevoxanthoendothelioma.

Nevoxanthoendothelioma.


A simplified theory of shock. The fundamental role of the myocardium.


New light on old eyes.

New light on old eyes.


Disorders of communion. Some observations on interpersonal tensions in general practice.


The use of norethindrone (2 Mg.) with mestranol (0.1 Mg.) in fertility control; a preliminary report. Norethindrone 2 mg. with mestranol 0.1 mg. (Ortho-Novum 2 mg.) was taken in cyclic fashion for fertility control by 62 private patients through 312 cycles. Each patient was interviewed every month during the trial period. No pregnancies occurred. The most common side effects noted were breakthrough bleeding, headache, fatigue and tension, nausea and depression. Five patients left the study because of depression and one because of nausea. It is suggested that the use of norethindrone 2 mg. with mestranol 0.1 mg. be reserved for the following situations: (1) those patients who have used other methods without success and in whom a further pregnancy would, in the opinion of the family physician, create hardship; (2) those patients in whom fear of pregnancy is part of the cause of marital problems; and (3) those patients in whom the product is primarily used for the treatment of menstrual disorders.


Four hemoglobins in each of three brothers. Genetic and biochemical significance.


A fetal hemoglobin variant of unusual genetic interest.


Abnormal haemoglobins in the neonatal period and their relationship to thalassaemia.


Follow-up study of patients with benign mucosal polyps of the rectum.


Maternal response to childhood aggression and subsequent anti-semitism.


The incidence and significance of Trichomonas infestations.


The nucleic acid response to skin homografts: a quantitative and cytochemical study.


The kinesiology of muscles of the thumb: an electromyographic study.


Kentucky's radiological safety program.

Kentucky's radiological safety program.


Use of electrosurgery in head and neck.

Use of electrosurgery in head and neck.


Possible interpretation of the slow-decaying EPR signal in algal suspensions.


Radioactivity in surface waters of the United States, 1957-1962.


Some central nervous system depressant properties of 2-methyl-3-o-tolyl-4(3H)-quinazolinone(TR-495).


Toxicopathologic and pharmacologic properties of piperacetazine, a potent tranquilizing agent.


Veratrum alkaloids. LI. Hypotensive-emetic relationships in the unanesthetized dog among analogs of the protoveratrines.


Acute upper respiratory disease in industry.


Recent concepts of interstitial cystitis.


Experimental and clinical studies of urethral regeneration.


Intravenous Alvodine. A clinical evalution.


Spectrophotometric determination of sodium 2,6-dimethoxyphenyl penicilin monohydrate (methicillin).


Robert Searson Rodney FRANCIS.

Robert Searson Rodney FRANCIS.


A plea for elucidation of basic ethical principles and systems.


Hypocalcaemic tetany and methaemalbuminaemia in acute fulminating pancreatitis.


Sex-role preferences and adjustment in early adolescents.


Hemorrhagic thrombocythemia. Response to busulfan.


Pediatric practice. A. The pediatrician as a specialist.


Blood banking.

Blood banking.


American Academy of Pediatrics. Acceptance of presidency.


Pediatric practice: C. The pediatrician as a teacher.


Pediatric practice: D. The pediatrician as a citizen.


Use of the Z-plastic procedure in uretero-ureteral anastomosis.


Clinico-pathological observations on monkeys infected with Kyasanur Forest disease virus, with special reference to the haemopoietic system.


Streptococcal gangrene.

Streptococcal gangrene.


Tick paralysis. A case report.

Tick paralysis. A case report.


Pharmacy.

Pharmacy.


The influence of diet on the quality of faecal fat in patients with and without steatorrhoea. By the use of gas-liquid chromatography it has been shown that the quality of the faecal fat in individuals without steatorrhoea is little affected by changes in the quality of the dietary fat. Large amounts of non-dietary fatty acids have been identified in the faeces both of patients with and without steatorrhoea. These have been identified as a number of isomers of oleic acid and hydroxystearic acids, particularly 10-hydroxystearic acid.


Breaking the sound barrier.

Breaking the sound barrier.


Determination of calcium in biological materials by means of the plasma-jet.


The biological action of cobalt and other metals. III. Chelation of cations by dihydrolipoic acid.


Suggestibility and verbal conditioning.

Suggestibility and verbal conditioning.


Solitary extramedullary myeloma (plasmacytoma) of the upper part of the respiratory tract and oropharynx.


Glycerol and water effects on x-ray sensitivity in Staphylococcus aureus.


Factors affecting the viability of air-borne bacteria. VI. The action of inositol on lactose oxidation by desiccated Escherichia coli.


Factors affecting the viability of air-borne bacteria. VII. The relationship between the structure of chemical additives and their action on air-borne cells.


Possible role for water and inositol in the structure of mucleoproteins.


The effect of sublethal doses of artificial sunlight on adaptive enzyme synthesis by Escherichia coli.


Some effects of prolonged sleep deprivation on the hooded rat.


A note on the sleep responses of young college adults.


Pericarditis due to histoplasmosis.

Pericarditis due to histoplasmosis.


Eye movements as a paradigm of approach and avoidance behavior.


Known transmission patterns of S. haematobium in Tanganyika and the possible influence of irrigation on incidence of infection.


Higher-carbon sugars.

Higher-carbon sugars.


Multiple ureteral diverticula. A case report.


The use of statistical theory in the study of the precipitin reaction.


Characteristics of acidic amino acid transport in mammalian kidney.


The early history of the Central Maine General Hospital.


On the mechanism of the relaxing effect of fragmented sarcoplasmic reticulum. The vesicles of fragmented sarcoplasmic reticulum, i.e. the physiological relaxing factor, remove most of the exchangeable Ca bound to actomyosin and myofibrils. The extent to which they remove Ca and the extent to which they inhibit myofibrillar activity are closely correlated. Previous work has shown that those in vitro reactions of actomyosin with ATP which are equivalent to its contraction, i.e. superprecipitation and a high ATPase activity, require the formation of a Ca-actomyosin complex, and that actomyosin after the removal of most of its bound Ca is inhibited by physiological concentrations of ATP. The evidence now suggests that the factor achieves its relaxing effect through the dissociation of the Ca-actomyosin complex and that it has no other direct influence on the biological activity of actomyosin. Experiments, showing that under similar conditions the vesicles of the factor are capable of reducing the concentration of ionized Ca in the surrounding medium to about 0.02 microM and less, suggest that the factor competes successfully with actomyosin for the available Ca through its mechanism of Ca accumulation.


Bilirubin monoglucuronide (pigment I): a complex.


The binding of calcium to actomyosin systems in relation to their biological activity.


Quantitative separation and determination of bilirubin and conjugated bilirubin in human serum.


Equilibrium sedimentation of uniform rods of tobacco mosaic virus. Equilibrium was achieved in centrifugal fields with tobacco mosaic virus by the Beams magnetically suspended ultracentrifuge. An attempt was made to account for the earth's gravitational component by using tilted cells in the rotor. The determinations of particle weight on highly uniform rods of tobacco mosaic virus in the apparent absence of nonideal behavior gave a value of (41.6 +/- 0.1) 10(6).


Biochemical investigations in malignant tumors of the skin.


Enzymes in the human skin.

Enzymes in the human skin.


The organization of camps for delinquent boys.


The peripheral angiopathy of diabetics. A plethysmographic and histopathological study.


Biochemical studies of subretinal fluid. II. Total protein and albumin of subretinal fluid and blood serum in patients with retinal detachment.


Long-term antibacterial treatment for pulmonary tuberculosis in patients older than 50 years.


The isolation and identification of a naphthoquinone from electron-transport particles of Mycobacterium phlei.


Clinical and laboratory studies of sodium diphenicillin. II. Clinical studies, with emphasis on the rate of disappearance of staphylococci from various lesions.


Oxidation of 4- and 5-hydroxyindole derivatives by mammalian cytochrome oxidase.


A correlative study of bone marrow and peripheral blood in bovine lymphosarcoma.


Drug contamination with diethylstilbestrol. Outbreak of precocious puberty due to contaminated isonicotinic acid hydrazide (INH).


Endotracheal anaesthesia for adeno-tonsillectomy: a modification of Doughty's technique.


Letters to the editor: a hazard of epidural anaesthesia in obstetrics.


Bronchopulmonary cryptococcosis.

Bronchopulmonary cryptococcosis.


The chromatographic separation of ester and free cholesterol in blood.


Intermediate reactions in the phosphorylation coupled to the oxidation of reduced cytochrome C.


Azotemic renal osteodystrophy.

Azotemic renal osteodystrophy.


Population biology.

Population biology.


Observations on the presence of lysolecithin in nervous tissues.


On the acylation of lysolecithin by rat-liver and brain mitochondria.


Schwann cell alterations in metachromatic leukodystrophy: preliminary phase and electron microscopic observations.


Asbestosis in non-experimental animals in South Africa.


The nature of the kallidins released from human plasma by kallikreins and other enzymes.


Immunological properties of the kallikreins.


Busman's holiday being a somewhat cursory account of a W.H.O. fellowship tour. III.


Busman's holiday--being a somewhat cursory account of a W.H.O. fellowship tour.


Busman's holiday: being a somewhat cursory account of a W.H.O. fellowship tour.


Pattern discrimination as a function of fill, distortion, and noise.


Problems of emotional development in young retarded children.


Oral florid papillomatosis. Clinical, pathological and electron microscopic observations.


Skin grafting the hand.

Skin grafting the hand.


Metabolism of chlorpromazine by mitochondria.


Newer developments in penicillin immunochemistry.


Conditions for the replication of infectious viral RNA.


Effect of puromycin on the replication of Western equine encephalitis and poliomyelitis viruses.


A severity scale of brain injury. A cross-validation study.


Normal and abnormal sensory patterns: pain. II. "Activity pattern" hypothesis for sensation of pain.


The pathogenesis of leprosy. An experimental approach.


WUHF-TV (Channel 31).

WUHF-TV (Channel 31).


Angiotensin II in the treatment of shock.


The radioisotope renogram in normal subjects.


Renl tubular localization of chlormerodrin labeled with mercury-203 by autoradiography. An autoradiographic technique has been developed for determining the intrarenal distribution of therapeutic doses of chlormerodrin labeled with mercury-203. Highest concentrations of mercury were detected in the straight portion of the proximal tubule in the rat and in the convoluted portion of the proximal tubule in the dog.


Objective auditory tests on non-cooperative children. A follow-up examination of 50 newborn infants and pre-school children with suspected hearing loss.


Congenital absence of the gallbladder.

Congenital absence of the gallbladder.


Gallstone ileus.

Gallstone ileus.


The strength in what remains.

The strength in what remains.


The problem of Salmonella organisms in animal by-products and feeds.


Origin of the Aschoff body.

Origin of the Aschoff body.


Acute intestinal obstruction due to orange sections bezoar following subtotal gastrectomy.


Adenomyosis: twenty years' experience.

Adenomyosis: twenty years' experience.


Rehabilitation following interscapular amputation: a case report.


Mobile safety hood for collection of sputum induced by aerosol inhalation.


Listeriosis, a clinical, epidemiologic, and microbiologic puzzle.


Topics in microbiology. Cat-scratch disease.


Topics in microbiology. Saprophytic acid-fast bacilli in granulomas.


Topics in microbiology: noncaseous granuloma--compatible with Boeck's sarcoid--etiology to be determined.


Is hemoglobin an essential structural component of human erythrocyte membranes?


Ten year study of carcinoma in situ.

Ten year study of carcinoma in situ.


Primary carcinoma of the fallopian tube; a ten year study, 1952-1961.


Absorption coefficients of liquid water and aqueous solutions in the far ultraviolet.


Lipogranuloma of mesentery producing abdominal mass.


Pigment of Flavobacterium piscicida.

Pigment of Flavobacterium piscicida.


Hemorrhage in the newborn and vitamin K prophylaxis.


Successful provocation of an acute attack of periodic benign synovitis in the hip joint by oestrogen and progesterone treatment.


The hexosamine content of the orbit in relation to anti-thyrotrophin antibody titres in sera of thyrotrophin-treated rabbits with and without cortisone administration.


Acute leukemia in children. A review of 229 cases treated according to different principles.


Vapor toxicity of UDMH in rats and dogs from short exposures.


Annual summary of vital statistics--1961.


The changing nature of public health.

The changing nature of public health.


The world before us.

The world before us.


Catecholamine content of various organs in experimental hypertension.


Incidence of Klinefelter's syndrome among juvenile deliquents and felons.


Incorporation of isobutyrate and valerate into cellular plasmalogen by Bacteroides succinogenes. Wegner, G. H. (University of Wisconsin, Madison) and E. M. Foster. Incorporation of isobutyrate and valerate into cellular plasmalogen by Bacteroides succinogenes. J. Bacteriol. 85:53-61. 1963.-Bacteroides succinogenes was found to require both a branched-chain volatile fatty acid (e.g., isobutyric) and a straight-chain acid (e.g., valeric) for growth. The organism used the acids as precursors for the synthesis of long-chain fatty acids and fatty aldehydes, which in turn were employed in the synthesis of phospholipid, mainly ethanolamine plasmalogen. Isobutyric acid was incorporated primarily into branched-chain C(14) and C(16) acids (tentatively identified as 12-methyl tridecanoic and 14-methyl pentadecanoic acids, respectively), and into fatty aldehydes. Valeric acid was used mainly for the synthesis of n-C(13) and n-C(15) fatty acids and fatty aldehydes. Apparently the two short-chain fatty acids were built up by the addition of two-carbon units to form the long-chain acids and aldehydes of the plasmalogen.


Preparing for a manpower survey.

Preparing for a manpower survey.


The benefits of a corrective therapy program in a private hospital.


Parasitic arthropods of rats from the town and port of Gdynia.


Effect of systemic venous pressure on drainage of lymph from thoracic duct.


A plea for constructive iconoclasm.

A plea for constructive iconoclasm.


Trophoblastic diseases in Taiwan. A review of 157 cases in a 10 year period.


A quantitative approach to the morphologic study of the peripheral pulmonary vasculature.


Principles and methods for the morphometric study of the lung and other organs.


Action of thalidomide.

Action of thalidomide.


Catalase activity of Proteus L forms and normal Proteus bacteria.


Occurrence of catalase in pleuropneumonia-like organisms and bacterial L forms. Weibull, C. (Central Bacteriological Laboratory of Stockholm City, Stockholm, Sweden) and Kerstin Hammarberg. Occurrence of catalase in pleuropneumonia-like organisms and bacterial L forms. J. Bacteriol. 84:520-525. 1962.-The catalase activity of six pleuropneumonia-like organisms (PPLO), four stable Proteus L forms, and four normal strains of Proteus mirabilis was determined quantitatively. The PPLO (strains of the species Mycoplasma agalactiae, hominis, laidlawii, mycoides, and strains isolated from tissue cultures) exhibited no measurable catalase activity. The L forms decomposed H(2)O(2) approximately ten times as rapidly as the normal bacteria from which they were derived.


Size and shape of pleuropneumonia-like organisms grown in liquid media. Weibull, C. (Central Bacteriological Laboratory of Stockholm City, Stockholm, Sweden), and Britt-Marie Lundin. Size and shape of pleuropneumonia-like organisms grown in liquid media. J. Bacteriol. 84:513-519. 1962.-Samples of liquid cultures containing mainly nonaggregated cells of Mycoplasma agalactiae or M. laidlawii were transferred to agar blocks containing the same medium as the liquid cultures. By use of a phase-contrast microscope, photomicrographs were made of the slide cultures immediately after they had been prepared, and the dimensions of a large number of pleuropneumonia-like organisms (PPLO) were measured. These measurements indicated that, in young cultures (incubated for 24 to 48 hr), the size of the cells did not vary much more than that of ordinary bacteria; 95% of the cells had a width of 0.2 to 0.6 mu. The growth of individual PPLO was followed during incubation of the slide cultures. It was found that 80 to 100% of the cells present in liquid overnight cultures divided and gave rise to microcolonies within a few hours. Rod-shaped, ellipsoidal, and spherical cells were seen in these cultures. Liquid cultures incubated for several days contained mainly spherical cells. Fewer than 5% of the cells in these cultures showed any indication of growth during incubation in slide cultures for 5 days. Photomicrographs of cells of M. agalactiae moving freely in liquid medium were taken with an electronic flash as the light source. The photographs thus obtained directly demonstrated the existence of rod-shaped cells.


Morphology of pleuropneumonia-like organisms and bacterial L forms grown in liquid media. Weibull, C. (Central Bacteriological Laboratory of Stockholm City, Stockholm, Sweden) and Britt-Marie Lundin. Morphology of pleuropneumonia-like organisms and bacterial L forms grown in liquid media. J. Bacteriol. 85:440-445. 1963.-Cells of Mycoplasma hominis, M. laidlawii, and two tissue-culture strains of pleuropneumonia-like organisms (PPLO) moving freely in liquid medium were photographed with an electronic flash as the light source. The photomicrographs thus obtained demonstrated that, in young cultures of high viability, the cells of these organisms were mainly filamentous or, in the case of M. laidlawii, coccoid. In old cultures of the same organisms containing predominantly nonviable cells, granular and vesicular elements were found. By the use of the same photographic technique, liquid cultures of a stable Proteus L form were studied. Although no filaments of uniform thickness were found, there were spherical bodies and some threadlike material connected with the spheres. When samples of PPLO cultures containing filamentous forms were transferred to agar blocks, the filaments were converted to more or less spherical bodies. This conversion could be prevented by fixing the PPLO with formaldehyde. The morphology of Proteus L forms was not noticeably altered by fixation with this reagent.


Size of minimal reproductive units of bacterial L forms.


Characterization of some urinary protein fractions in patients with multiple myeloma.


Hypoglycemia in chick embryos infected with S. typhosa via the allantoic cavity.


Autolytic enzymes as a source of error in the preparation and study of gram-negative cell walls.


Treatment of psoriasis and other dermatoses with intralesional injections of triamcinolone acetonide.


The effect of fluoride on bone.

The effect of fluoride on bone.


Observations concerning progressive pulmonary vascular obstruction in children with ventricular septal defects.


Preoperative x-ray diagnosis of gallstone ileus.


The excretion of Na-22 in sweat.

The excretion of Na-22 in sweat.


Excretion of P-32 after therapy for polycythemia rubra vera.


Total body radiation to the blood from radioactive phosphorus.


Termination of acquired immunological tolerance to protein antigens following immunization with altered protein antigens. Acquired tolerance to BSA in rabbits was terminated following the injection of certain preparations of altered BSA. Injections of Freund's adjuvant containing BSA complexed to anti-BSA, heat-denatured BSA, acetyl-BSA, picryl-BSA, or arsanil-BSA failed to terminate the tolerant state. Except in an occasional tolerant rabbit, injections of these preparations failed to cause the production of precipitating antibody to the altered preparation. Similar results were obtained following injections of alum-precipitated preparations of pepsin-degraded BSA, acetyl-BSA, and picryl-BSA. Injections of Freund's adjuvant containing sulfanil-BSA terminated the tolerant state, but only small amounts of non-precipitating anti-BSA were produced. Injections of Freund's adjuvant containing picryl-acetyl-BSA terminated the tolerant state in two of six rabbits, but again, only small amounts of non-precipitating anti-BSA were produced. Injections of an alum-precipitated preparation of picryl-acetyl-BSA failed to terminate the tolerant state. On the other hand, injections of Freund's adjuvant containing arsanil-sulfanil-BSA terminated the tolerant state in eleven of eleven rabbits and caused the production of precipitating anti-BSA in all nine of the rabbits tested. The tolerant state was terminated also in six of six rabbits injected with an alum-precipitated preparation of arsanil-sulfanil-BSA. Only one of these rabbits produced precipitating anti-BSA. In addition, the injection of BGG-tolerant rabbits with arsanil-BGG, sulfanil-BGG, or arsanil-sulfanil-BGG terminated the tolerant state. These results were discussed in relation to both the clonal selection theory of antibody production and autoimmunity.


Assessment of radiation damage by means of peripheral blood cultures.


The mechanism underlying the response of polycythemia rubra vera to therapy with radioactive phosphorus.


Aetiology and diagnosis of fermentative diarrhoeas.


Absorption, excretion and fate of prodilidine.


Toxicological and pharmacological criteria of repeated doses of a hepatotoxic agent.


New treatment of psoriasis and other dermatoses. Action of certain carraghenates and certain alginates in dermatologic therapy


The superego and the ego-ideal.

The superego and the ego-ideal.


The head-down position in treatment of shock.


The subviral infective agent from Polyoma virus.


The denaturation and the renaturation of the DNA of polyoma virus.


Fluoridation: analysis of an unsuccessful community effort.


The effect of drugs on the release of epinephrine from adrenomedullary particles in vitro.


West Virginia doctors in the Civil War.

West Virginia doctors in the Civil War.


Cytological confirmation of female heterogamety in the African water frog (Xenopus laevis).


The effect of estradiol injections upon chicken liver nuclei ribonucleic acid polymerase.


Metabolites of catecholamines in urine and tissues.


Thin-layer chromatography of deoxyribo-oligonucleotides.


Studies with a constitutive aldose dehydrogenase in Pseudomonas fragi.


Radiological diagnosis of extra-uterine pregnancy.


The development of a benign bone tumor following trauma.


Electric shock hazards in cardiac catherization.


Vagotomy and pyloroplasty in the treatment of duodenal ulcer.


Common non-ulcerative conditions of the gastrointestinal tract.


Functional and esthetic planning for full coverage.


Pulmonary valvulotomy and infundibulotomy in infants.


Absence of analytic bias in a quality control program.


Abdominal cystocele repair. Technic and results in 96 cases.


Preparation of a stable suspension of hemoglobin.


"Resistance" to systematic desensitization of phobias.


Relativism, self-centering, and conceptual level.


Primary hyperparathyroidism presenting as renal calculi. Report of a case.


Physiologic alterations of the experimentally-induced obstructed ureter.


Cloth wrapping of unfavorable abdominal aortic aneurysms.


Dynamics of arterial circulation of pelvis as related to chemotherapy of bladder cancer: experimental and clinical study.


Ligating the vessel in the bleeding duodenal ulcer.


Analexin, a non-narcotic analgesic. Some characteristics and effects in the management of surgical and other podiatric patients.


Changes in employment status associated with hospitalization for tuberculosis. I. Analysis of 163 consecutively admitted males.


Changes in employment status associated with hospitalization for tuberculosis. II. Significant characteristics associated with success or failure in achievement of employability.


On the psychology of personal freedom.

On the psychology of personal freedom.


Operant programming with transistorized digital elements.


Hepatic function in acne vulgaris patients treated with triacetyloleandomycin: A preliminary report.


Response cost and the aversive control of human operant behavior. The effects of cost (point-loss per response) upon human avoidance, escape, and avoidance-escape behavior maintained by PLPs (point-loss periods) were investigated. Cost had a marked but differentially suppressive effect upon responding under all schedules. The greatest number of PLPs taken under cost occurred on the escape schedule. In most instances PLPs were more frequent on the avoidance-escape schedule than on the avoidance schedule under cost. Inferior avoidance performance appeared only under cost conditions. Under no-cost, all subjects (Ss) successfully avoided all PLPs after the first hour of conditioning. These results indicate that the development and maintenance of human avoidance and escape behavior may, in part, be dependent upon response cost conditions. Aversive control of human operant behavior may be limited without an adequate specification of response-cost conditions.


Father-daughter incest: a clinical report.


Studies on mercurial diureis: renal excretion, acid stability and structure-activity relationships of organic mercurials.


Clot retraction and fibrinolysis.

Clot retraction and fibrinolysis.


Electrophoresis and imunoelectrophoresis in an agar gel-paper medium.


Cardiovascular responses and their psychological correlates. I. A. study in healthy young adult and patients with peptic ulcer and hypertension.


Talking to your problem patients.

Talking to your problem patients.


Labor and the community rehabilitation effort: a pilot project.


Medical care in prepaid group practice.

Medical care in prepaid group practice.


The patient's viewpount of group health care.


Antagonistic relationship between myo-inositol and 2-O, C-methylenemyo-inositol in animals.


Role of the liver in blood glucose homeostasis.


Problems of diagnosis of trypanosomasis. Diagnostic problems in trypanosomiasis arise from the inadequacy of current diagnostic procedures. This inadequacy deprives the clinician of essential data, hinders individual therapy and therapeutic control programmes, and makes suspect many conclusions drawn from previous experimental work. In this paper the author examines alternative methods of diagnosis, emphasizing cultivation and immunological procedures.An independent standard for diagnostic evaluation is available with the culture method. Comparison indicates that conventional procedures are frequently in error and that the error is always an underestimation, which may reach 20%-25% or more. The culture method has proved to be sensitive, reliable, usable under African field and hospital conditions, and applicable to isolation of Trypanosoma gambiense and T. rhodesiense from both blood and spinal fluid.Complement-fixation is the most widely used of the immunological reactions available. Procedures and results are reviewed and possibilities both with this method and others are discussed.Continuing research on diagnostic methods is needed, and certain practical difficulties in such a continuing research programme are discussed.


The effect of cortisone on mucosal resistance to ulceration.


The use of azepinamide in the management of diabetes mellitus, with a report of jaundice as a complication, and comments relative to the use of oral hypoglycemic agents.


A note on comparison of differences between several religious groups of adults on various measures of the Rosenzweig Picture-Frustration Study.


Effects of insulin on hepatic glucose production and utilization.


A chromosomal abnormality in acute myeloblastic leukemia.


Diabetes: a regional survey in British Guiana. (Preliminary report).


The symptomatology of tropical eosinophilia.


Hyperthyroidism masked by psychotic depression.


Obstructive jaundice as a complication of pancreatis.


In memoriam: Israel Spanier WECHSLER, M.D. (1886-1962).


Meckel's diverticulum: 55 years of clinical and surgical experience.


Intrussuscepting hemangiomas of the gastro-intestinal tract: report of a case and review of the literature.


Retroperitoneal pelvic ganglioneuroma: report of case.


VA day care treatment program.

VA day care treatment program.


The absorption and toxicity of ethionamide.


Studies of subcellular distribution of gamma-aminobutyric acid and glutamic decarboxylase in mouse brain.


Current appraisal of diagnosis and treatment of bronchogenic carcinoma.


Ethical considerations in air pollution research.


Calcifying epithelioma of Malherbe.

Calcifying epithelioma of Malherbe.


Resection and reconstruction of the mandible for removal of a central hemangioma.


Reticulocyte protein synthesis: response of ribosome fractions to polyuridylic acid. Reticulocyte ribosomes with sedimentation coefficients greater than 100S ("heavy" ribosomes) appear to be considerably more active in hemoglobin synthesis than are 78S ribosomes. When assayed for the ability to synthesize polyphenylalanine in the presence of polyuridylic acid, the 78S ribosomes and "heavy" ribosomes have similar activities. Polyuridylic acid inhibits incorporation by "heavy" ribosomes of amino acids other than phenylalanine.


Studies of intracranial and orbital vasculature of the rhesus monkey (Macaca mulatta).


Plasma concentrations and antibacterial activity of sulfadiazine and triple sulfapyrimidines in man.


The misuse and abuse of antimicrobial agents.


Tonography and electrocardiography.

Tonography and electrocardiography.


The relationship of laterality and cutaneous area to breast-sensitivity in sinistrals and dextrals.


Effects of certain quinones on renal excretion of sodium.


The action of drugs on the formation of transient lens opacities.


A new x-ray identification product.

A new x-ray identification product.


Giant cell tumor of tendon sheath origin (benign synovioma)--A case report.


Photographic reproduction of roentgenograms.


Medical photography.

Medical photography.


Demonstration of kinins in intestinal obstruction in dogs.


Successful treatment of ulcerative colitis by psychoanalysts: a survey of 28 cases, with follow-up.


Anaemia following gastric operations for peptic ulceration in Dublin.


Anaemia following gastric operations for peptic ulceration in Dublin. II. Deficiency of iron and vitamin B12.


Problems in the evaluation of nutritional status in chronic illness.


Faomltative parasites and host respiration. I. Healthy tissue adjacent to the site of infection.


Facultative parasites and host respiration. III. Tissue which is actively parasitised.


Selection for leucocyte count in the house mouse and some physiological effects.


Paramesonephric lymph-node inclusions-a cause for obstructive uropathy. Report of a case.


Biphasic response of guinea-pig's taenia coli induced by 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP).


Investigations on some experimental inflammations in mouse paws.


Interactions of polyoma virus and organ cultures of embryonic mouse metanephric rudiments.


Problems in chemotaxonomy. I. Alkaloids of Peschiera affinis.


Social and nonsocial conditioning of infant vocalizations.


Protein synthesis by reticulocyte ribosomes. I. Inhibition of polyuridylic acid-induced ribosomal protein synthesis by chloramphenical.


Studies on differences in the genetic architecture of related species of Drosophila.


Endometrial stromal sarcoma.

Endometrial stromal sarcoma.


Metal ion complexing properties of carcinogen metabolites.


Hemodynamic effects of closed and open chest cardiac resuscitation in normal dogs and those with acute myocardial infarction.


Foods and folklore of the Christmas season.


1-alpha-Tocopherylacetate: biological activity. l-alpha-Tocopheryl acetate has 42 percent of the activity of d-alpha-tocopheryl acetate when compared in the rat hemolysis test. Based on this activity a potency ratio of 1.4 : 1.0 for d-alpha-tocopheryl acetate compared to dl-alpha-tocopheryl acetate was established; this confirms the currently accepted biological ratio. Preparations of dl-alpha-tocopheryl acetate from phytol and from isophytol were equally active in the rat hemolysis test.


A central institute on agricultural work health.


Symposium on chemical carcinogenesis. V. Pharmacodynamics of carcinogenic azo dyes. aromatic amines. and nitrosamines.


Diseases of insects of medical importance in Europe. The biological control of insects carrying human diseases was first attempted many years ago, but the results were disappointing owing to the insufficiency of information on the ecology and pathology of such insects at the time. In recent years, however, increased knowledge of insect pathology and ecology and the development of insecticide-resistance have led to a revival of interest in this method of vector control. Most of the recent published work on this subject relates to findings in North America; comparatively little information has hitherto been available in respect of Europe. This paper, which is based on a survey of the literature and on the author's own experience, presents the results of research on diseases of insects of medical importance in Europe. Infection with viruses, rickettsiae, bacteria, fungi, protozoa and nematodes are discussed and suggested lines for future European research on biological control are put forward.


Striate cortex lesions and visual acuity of the rhesus monkey.


Effects of stimulation of frontal cortex and hippocampus on behaviour in the monkey.


An experimental method for compressing the sciatic nerve.


The roentgenographic properties of Thiokol rubber-base materials.


Intra-arterial pressure studies in patients with arterial insufficiency of lower extremities.


A challenge to medicine.

A challenge to medicine.


Hematologic complications of renal disease.


Nephrotic syndrome secondary to primary amyloidosis with terminal bilateral renal vein thrombosis.


A foot electrode for monkeys.

A foot electrode for monkeys.


Effects of amphetamine, chlorpromazine and pentobarbital on behavioral theromoregulation.


A mathematical basis for the solvent-reversal technique of paper chromatography.


The biosynthesis of sphingosine. I. A study of the reaction with tritium-labeled serine.


Ritual circumcision. Comments on current practices in American hospitals.


Treatment of two cases of hyperglobulinemic purpura with thioguanine.


Treatment of malignant glaucoma with intravenous mannitol infusion. Medical reformation of the anterior chamber by means of an osmotic agent: a preliminary report.


Neovascular gluacoma complicating carotid-cavernous fistula.


Mydriatic effects of one-eight per cent phenylephrine. A potential cause of angle-closure glaucoma.


An artificial mastoid for testing of bone conduction instruments.


Personal injury neurosis in perspective.


Clinical evaluation of the basal metabolism. Current reappraisal of the BMR in 300 patients substantiates its value.


The effect of extended exposure to a hot environment on the response of the chicken to hyperthermia.


Effect of professional training and amount and accuracy of information on behavioral prediction.


Role of "meaningfulness" versus meaning dimensions in guessing the meanings of foreign words.


The demonstration of rupture of cell surfaces by an immunological technique.


Electron microscopic, observations on the vascular barrier in the cortex of the thymus of the mouse.


Studies on cellular adhesion in tissue-culture. V. Some effects of enzymes on cell-detachment.


The mammalian tissue cell surface.

The mammalian tissue cell surface.


Methocarbamol in low-back pain: clinical study.


Argument strength, delay of argument, and anxiety in the "conditioning" and "selective learning" of attitudes.


Anterior removal of cervical intervertebral disk with interbody fusion.


Postural diplopia-residuum of the decrebrate state. Report of a case.


Optical aids for the partially sighted. Practical aspects of prescribing.


Foreshortened phantom limbs and phocomelia.


Secondary reinforcement as a suppressor of rate of responding in the free operant situation.


The normal human intra-aural muscle reflex in response to sound.


Marital counseling. The role of the clinical psychologist.


Acoustic collicular evoked responses during cortical spreading depression in freely moving unanesthetized rats.


The clinical significance of Staphylococcus aureus in secretions of the lower respiratory tract.


The examination of bronchial secretions for tubercle bacilli.


Influence of unbalanced response scales on size judgments.


Scale judgments of triplets of opinion statements.


Reversal of thyroxine-induced hypermetabolism by puromycin. Previous studies have demonstrated that in addition to its effects on metabolic rate, thyroxine stimulates protein biosynthesis. The administration of puromycin, a drug which blocks protein synthesis and, therefore, the thyroxine effect on protein synthesis, acutely reverses the hypermetabolism induced in rats by prior administration of thyroxine and restores the oxygen consumption of the thyrotoxic rats to the euthyroid level. The results suggest that a larger fraction of the total body basal oxygen consumption in hyperthyroidism is related to the process of protein synthesis than in the euthyroid state and that the calorigenic effect of thyroxine is secondary to its effect on protein synthesis.


The effect of lysogenic induction on the deoxyribonucleases of Escherichia coli K12 lambda.


Biosynthesis of the B12 coenzyme: requirements for release of cyanide and spectral changes.


The Jewish anti-semite's perceptions of fellow Jews.


Immunization experiments against Ehrlich's ascites tumour.


Behavioral effects of pairing an S-D with a decreasing limited-hold reinforcement schedule. Four pigeons were trained on a multiple reinforcement schedule consisting of two limited-hold schedules, one in which a discriminative stimulus (S(D)) accompanied the periodic reinforcement contingency, and one in which the discriminative stimulus was omitted. The duration of the limited-hold in each component of the multiple schedule was reduced in parallel steps. It was shown that behavioral differences between the two schedules were attenuated by this manipulation of temporal parameters. When S(D) was reduced in duration, three out of four pigeons responded with extremely high S(Delta) rates, despite the regular pairing of S(Delta) with the reinforcement contingency. These high rates qualitatively resembled the rapid rates emitted on the analogous no-S(D) component.


Sinus of the first branchial cleft.

Sinus of the first branchial cleft.


The psychology of the critic and psychological critiscism.


The effects of preoedipal paternal attitudes on development and character.


Spontaneous osteolysis following acute osteomvelitis.


The metabolism of isotopically labeled uracil and uridine in man.


Induction by an RNA phage of an enzyme catalyzing incorporation of ribonucleotides into ribonucleic acid.


Prevention by hydrocortisone of changes in connective tissue induced by an excess of vitamine A acid in Amphibia.


Steroids, lyosomes and systemic lupus erythematosus.


Studies on lysosomes. I. The effects of endotoxin, endotoxin tolerance, and cortisone on the release of acid hydrolases from a granular fraction of rabbit liver. Granular fractions sedimenting between 800 g and 15,000 g have been prepared in 0.25 M sucrose from the livers of normal young rabbits and from the livers of rabbits injected with A. aerogenes endotoxin. As early as 5 minutes after endotoxin, there was an augmented release of two enzymes, beta glucuronidase and cathepsin, into the supernatant of fractions which had been incubated or incubated and irradiated with a mercury vapor lamp at 37 degrees C. These effects were maximum at 30 minutes after endotoxin and were associated with a depletion of the total activities of the two enzymes within the granules. Concurrently there was a rise in the activity of the two enzymes in fractions of the homogenate which were unsedimentable at 15,000 g. Fractions prepared from animals made tolerant to endotoxin no longer responded to incubation and irradiation by an augmented release of these two hydrolases, nor did fractions prepared from animals pretreated with glucocorticoids. Pretreatment with DOCA did not prevent release of enzymes after endotoxin. The results have been interpreted to indicate that one consequence of the injection of endotoxin is an effect upon the stability of lysosomes, with subsequent release of acid hydrolases into the cell sap or surrounding tissue. Glucocorticoids may exert their pharmacologic effects through the protection of these subcellular particles against a variety of injurious agents.


Acute hypervitaminosis A in guinea pigs, I, Effects on acid hydroalases.


Studies on lysosomes. II. The effect of cortisone on the release of acid hydrolases from a large granule fraction of rabbit liver induced by an excess of vitamin A.


The feeding habits of Glossina.

The feeding habits of Glossina. The feeding habits of 15 species of Glossina have been studied by the identification of their blood meals. Representative samples of the blood meals from each of these species of tsetse fly and from different habitats were collected and 22 640 blood meals were identified. The feeding patterns are characteristic for each species of tsetse fly and do not appear to depend entirely on the availability of different hosts, suggesting that the feeding habits of Glossina are genetically determined. However, a broad grouping can be made into five categories: species feeding mainly on suids, those feeding on suids and bovids, those feeding mainly on bovids, those feeding mainly on mammals other than suids and bovids, and those feeding on most available hosts and on man.The possibility of control by selective elimination of the main hosts of these groups is discussed.


Estimation of hypnotic susceptibility in a group situation.


Carcinoma arising in a rectal duplication (enterocystoma).


The nature of hypnosis. I.

The nature of hypnosis. I.


The nature of hypnosis, II.

The nature of hypnosis, II.


A figural aftereffect produced by a phenomenal dichotomy in a uniform contour.


A threshold difference produced by a figureground dichotomy.


Juvenile xanthogranuloma (nevoxanthoendothelioma).


Health education for the younger child: with special reference to Buganda.


Health education and accident prevention.


Effect of ventilating air flow on human water requirements.


Gastrointestinal fistulas.

Gastrointestinal fistulas.


A novel approach to the control of ventilation: an auditory respiration simulator.


Partial gastrectomy for duodenal ulcer.

Partial gastrectomy for duodenal ulcer.


Abdominal surgery.

Abdominal surgery.


Gastric hypothermia.

Gastric hypothermia.


Effects of morphine, levallorphan, and respiratory gases on increased intracranial pressure.


Patent ductus arteriosus in flying personnel.


Complete heart block treated surgically.


Hypocalcemic tetany associated with dumping syndrome.


Qualitative detection of urobilinogen in gastric aspirate as test for portal bleeding.


Early squamos cell carcinoma of the cervix: selection of cases for surgical management.


Weaning among the Baganda.

Weaning among the Baganda.


Some problems involved in the preservation of the practice of medicine.


The spinal arachnoid villi of the monkeys Cercopithecus aethiops sabaeus and Macaca irus.


Production of octadecenoic acid in plasma by Staphylococcus aureus.


Chicken-pox and the Guilain Barre syndrome.


Joseph Isaac KEMLER, 1884-1962.

Joseph Isaac KEMLER, 1884-1962.


Metabolism of progesterone-4-C-14 and pregnenolone-7alpha-H3 by human adrenal tissue. Formation of 16alpha-hydroxyprogesterone-C-14, corticosterone-C-14, and cortisol-C-14-H3.


Advances in roentgen diagnosis of ulcerative colitis.


Physiological significance of sulci in somatic sensory cerebral cortex in mammals of the family procyonidae.


Effects of stimulus novelty on gnawing and eating by rats.


The effect of thyrotrophic hormone on the plasma thyroid hormones in man.


The circulating thyroid hormones in thyrotoxicosis.


Methods for the separation and identification of the iodine-containing amino acids in human plasma.


The essential oils in Pharmacopoea Danica 1948. Gas chromatography and thin layer chromatography.


The phenformin timed-disintegration capsule (DBI-TD) in the management of previously treated diabetic patients.


Effect of chlorothiazide on blood pressure and electrolytes of normotensive and hypertensive rats.


Sodium and potassium abnormalities in hypertension.


Aneurysm of coronary arteries in an infant.


On glycolysis in Trichomonas vaginalis.

On glycolysis in Trichomonas vaginalis.


The metabolism and excretion of methohexital in the rat and dog.


Electron microscopy of milk secretion in the mammary gland of the C3H/Crgl mouse. III. Cytomorphology of the involuting gland.


Electron microscopy of sclerosing adenosis and infiltrating duct carcinoma of the human mammary gland.


Electron microscopic studies on the subcellular origin and ultrastructure of melanin granules in mammalian melanomas.


Bronchiolar (alveolar cell) carcinoma of the lung.


Primary hemangiopericytoma of the lung.

Primary hemangiopericytoma of the lung.


Demonstration of acid-fast bacilli in tissue sections by fluorescence microscopy: a study with clinical and histopathological correlations.


Expectancy shifts under three conditions of reinforcement for paranoid and depressed patients.


Enzymatic activity of polyalanyl ribonuclease.


Laboratory suggestion: convenient pipet rack.


Comparative effects of pectin N. F. administration on the cholesterol-fed rabbit, guinea pig, hamster and rat.


An evaluation of acridine-orange fluorescence microscopy in cytology.


Transfusion reactions.

Transfusion reactions.


Increased tolerance to cerebral ischemia produced by general anesthesia during temporary carotid occlusion.


Effect of anticoagulant therapy on serum cholesterol levels.


A study of acidulated fluoride solutions. II. The caries inhibiting effect of single annual topical applications of an acidic fluoride and phosphate solution. A two year experience.


Alkaptonuria in an Egyptian mummy.

Alkaptonuria in an Egyptian mummy.


Effects of transfer and problem structure in disjunctive concept formation.


Three cases of aural pathology of Anglo-Saxon date.


The neural regulation of salivary gland growth.


Trigeminal and pretectal influences upon slow-wave activity of the ventral tegmental area in the cat.


Fetal electrocardiography for the diagnosis of fetal life.


The surgical treatment of pulmonary tuberculosis.


Congenital deficiency of the vertebral pedicle.


Variation in the human vertebral column, with particular reference to the lumbo-sacral junction.


Development of the pancreas of the mouse embryo in vitro: acini and islets.


Humidification of oxygen during inhalational therapy.


Hepatoma: review of 43 cases with comments on syphilis as an etiologic factor.


The general practitioner and the industrial physician.


An evaluation of the dental health program in El Dorado County Schools, California.


The effect of intensive physical training upon body composition of adolescent girls.


Egg yolk and serumcholesterol levels: importance of dietary cholesterol intake.


Growth, body composition and physical efficiency.


Hypothermia in acute hemorrhagic pancreatitis. Experimental study and clinical trial.


Hernia surgery--over seventy age group.

Hernia surgery--over seventy age group.


Colon blood flow.

Colon blood flow.


Determination and identification of p-hydroxyamphetamine as the O, N-diacetyl derivative.


Analysis of laryngeal compartments.

Analysis of laryngeal compartments.


The cervical lymphatics, human in vivo studies.


Unilateral sensorineural deafness.

Unilateral sensorineural deafness.


Light and electron microscopic observations of scleroma.


The Association of Remedial Gymnasts (Ontario).


A myoelectric system for training functional dissociation of muscles.


Acne: additional data from a national survey.


Community health: a cooperative responsibility.


What medical students think of psychiatry and psychiatrists.


Compulsion versus freedom. A Swedish businessman's thoughts about medical care.


The short term prospective model, the illusion of time, and the tabula rasa child.


Dementia praecox: the development of the concept.


Lethal bronchophraxis in asthmatic schizophrenics without status asthmaticus.


Recognition of acute myocardial infarction in the deteriorated elderly psychotic patient.


The hemodynamics and cardiac metabolism in cardiomyopathies.


Self-maintained visual stimulation in monkeys after long-term visual deprivation. Newborn monkeys reared in darkness for 16 months, except for daily 1-hour periods of exposure to unpatterned light, were allowed to press a lever to obtain unpatterned light. The animals showed apparently insatiable responding, at rates that were extremely high as compared with rates for normally reared control animals.


Fat absorption after total gastrectomy. An experimental study on rats.


Evaluation of methyclothiazide therapy for angina pectoris.


Paroxysmal tachycardias in infants.

Paroxysmal tachycardias in infants.


Metabolic effects of catecholamines.

Metabolic effects of catecholamines.


Serum lactic dehydrogenase levels of mice inoculated with oncogenic and non-oncogenic viruses.


Extensive intraventricular conduction defect. Experimental production with destruction of total Purkinje-net system of the canine right ventricle.


The metabolism of alpha-glycerophosphate and pyruvate in ascites tumor cells.


Problems in working with enteroviruses.

Problems in working with enteroviruses.


The ECHO viruses.

The ECHO viruses.


The galactokinetic properties of synthetic oxytocin administered by the intranasal route.


A case with a vena cava superior on both sides.


Medicine in Thailand.

Medicine in Thailand.


Response strength of an operant under stimulus control with satiated subjects.


Ecological implications of the autonomous 24-hour rhythm in plants.


C.A.R.I. aeromedical symposium. Studies on aviation personnel aging.


The significance of mucosal lesions antedating mouse cervical cancer.


Interaction of ouabain and malonate upon the contractile response of myocardium.


Effects of early postnatal hemidecortication on spatial discrimination in cats.


Poisoning from a malathion-aerosol mixture. A case report.


Filmstrips as an adjunct to language therapy for aphasia.


The postgraft membrane.

The postgraft membrane.


Postnatal behavioral effects of tranquilizers administered to the gravid rat.


Learning deficits of offspring after administration of tranquilizing drugs to the mothers.


Hypersensitive vascultis of the skin. Report of a case caused by focal infection of the facial bone.


Toxic effects of tranquilizers administered to gravid rats.


Effects of cerebral lesions, blinding, and domestication on gonadal functions of the female ferret.


A future for the young physician.

A future for the young physician.


Refections on the USAREUR Medical Service.


Further studies of adrenocortical function in patients with carcinoma of the lung.


Kallikrein, kallidin, kallikrein inhibitors.


The different research roles in army nursing.


Electrical inexcitability of the frog neuromuscular synapse. Frog muscle endplates were explored with an extracellular microelectrode. An intracellular microelectrode nearby simultaneously monitored invasion of the endplate by a spike directly evoked by a third microelectrode placed away from the endplate in the same fiber. External positivities were seen only at sites generating miniature endplate potentials. The external positivity reached a maximum prior to the internally recorded potential and was followed by a small late negativity. Small movements away from active synaptic sites resulted in positive-negative-positive potential sequences characteristic of activity and propagation. Since the external potential is a function of membrane current, the absence of negativity associated with the rising phase of the spike indicates the absence of inward current at synaptic sites. Thus, the synaptic membrane appears not to be excited by a depolarization of the magnitude of an action potential. In an Appendix it is shown that the late negativity and earlier maximum of the external potential can be accounted for by capacitative current through passive membrane.


Compression fracture of the femoral head in association with cortisone therapy.


Training social work students for an expanding mental health clinic program.


Psychotherapy and consciousness: a preliminary statement.


Presence of iodine-127 iodotyrosines in extracts of normal human serum.


Clinical use of triiodothyronine in suppressing thyrotrophin secretion by the anterior pituitary: a survey.


The use of the hypnoreflexogenous technique in obstetrical delivery.


Can advertising be harmful?

Can advertising be harmful?


Society and problem personalities: praetorian psychiatry.


A histochemical study of hyaline bodies in odontogenic cysts and a comparison to the human secondary dental cuticle.


Medical libraries overseas.

Medical libraries overseas.


A psychiatric follow-up of children with rheumatic fever and other chronic diseases.


Schizophrenic sub-diagnosis and age at menarche.


Influence of diabetes on carbohydrate metabolism of aortic tissue.


Clinical and arteriographic examination of obliterations of the cerebral arteries.


Gastroscopic appearance of the petrified stomach.


The site of the primary lesions in atherosclerosis.


Catalase in insect trypanosomatids.

Catalase in insect trypanosomatids.


The have and have-not medical schools. Cause, effect and correction.


The dynamic life in age of explosions.

The dynamic life in age of explosions.


Corneal contour and contact lenses.

Corneal contour and contact lenses.


Some living commandments.

Some living commandments.


The compound prosthetic vascular graft: a pathologic survey.


Materials for repair of vascular defects.


Psychologic principles in pediatric residency training and practice.


Maternal and child nursing-as a pediatrician sees it.


Berberis vulgaris.

Berberis vulgaris.


Pathogenesis and surgical treatment of diverticulum of the urinary bladder.


The role of the university.

The role of the university.


Effects of extra-epithelial factors on the incorporation of thymidine by embryonic epidermis.


Separation of the two photochemical systems of photosynthesis by digitonin fragmentation of spinach chloroplasts.


Can the chronic schizophrenic patient remain in the community?: A follow-up study of twenty-four long-term hospitalized patients returned to the community.


Thrombosis in the presence of vascular stasis.


Clinical evaluation of renal function.

Clinical evaluation of renal function.


The romance of the epididymis and vas.

The romance of the epididymis and vas.


Immunoglobulin levels from the newborn period to adulthood and in immunoglobulin deficiency states.


The metabolism of ring-labeled L-thyroxine-C14 in vivo.


A note on the stability of solutions of isoprenaline.


Drugs and rat pregnancy.

Drugs and rat pregnancy.


Corticosteroid therapy for rheumatoid arthritis. Some practical and theoretical observations.


Ten years of ACTH therapy.

Ten years of ACTH therapy.


The impaired driver. A critical review of the facts. Traffic accidents have been subject to relatively little scientific study in California. A substantial barrier to adequate basic research in this field has been the assumption that more is known about the underlying causes of accidents than actually is. For example, within the medical profession, there is a tendency to assume that physical impairments of drivers are important in the causation of accidents, although little evidence has been collected to confirm or deny this assumption.Research into the underlying causes of accidents is a worthy but infinitely complex task. It must be accomplished before the driver's contribution to accidents can be seen in proper perspective, its components identified and dealt with on a rational basis.


Distribution of gas and blood in the normal lungs.


Regional differences in gas exchange in the lung of erect man.


The effect of uneven blood flow in the lung on regional gas exchange.


Facilitation of major hepatic resections by an innovation in the surgical exposure of the liver.


Rorschach and draw-a-person responses of hypnotized and nonhypnotized subjects.


Alveolar hydatid disease of the liver: rationale and technics of surgical treatment.


Effects of protoveratrine on coronary blood flow of the renal hypertensive dog.


Atrial and ventricular force of contraction influenced by intracoronary injections.


The disposal of hospital refuse.

The disposal of hospital refuse.


Use of the strut bone graft.

Use of the strut bone graft.


Integrating accident prevention in total patient care.


Vaginitis therapy evaluated. The treatment of trichomonal vaginitis with metronidazole.


Carotid body tumour treated by excision and arterial replacement.


Regional chemotherapy in malignant disease.


The nature of the antithyrotoxic effect of liver residue.


Nationally speaking: from the President, American Occupational Therapy Association.


An antithyrotoxic assay based uon the metabolic rate response.


Nationally speaking: the President's address, 1962 annual conference.


Value of the skin-surface glucose test as a screening procedure for diabetes.


The use of the renogram in obstetrics and gynecology.


On the mechanism of pituitary-adrenal stimulation by reserpine.


Billiary atresia: early diagnosis and management.


Effects of cigarette smoke on epinephrine secretion in the dog.


Emergency care of te head-injury patient--or what to do before the neurosurgeon arrives.


Changes in histamine blood levels following d-tubocurarine administration.


Enzymes and enzyme models.

Enzymes and enzyme models.


Optical and motor factors in the formation of the retinal image.


Hypothermia induced during asphyxiation: its effects on survival rate, learning and maintenance of the conditioned response in rats.


Aortic stenosis in children.

Aortic stenosis in children.


Hypothermia and transfusion with oxygenated blood in the treatment of asphyxia neonatorum.


Parallel group psychotherapy with theparents of emotionally disturbed children.


Influence of palmitate on the in vitro metabolism of glucose in epididymal adipose tissue from mice.


Mental health--an aspect of command.

Mental health--an aspect of command.


A radioautographic analysis of the migration and localization of trunk neural crest cells in the chick.


Biliobronchial fistula following right hepatic lobectomy for metastatic leiomyosarcoma of the stomach.


Fundamentals of operation of entrainment aerators.


Prediction of the performance of completely mixed continuous biological systems from batch data.


Congenital ball and socket ankle joint.

Congenital ball and socket ankle joint.


Thorn and twig-induced pseudotumours of bone and soft tissues.


The art of medicine.

The art of medicine.


An electron microscopic study of the stratum radiatum of the rat hippocampus (regio superior, CA 1) with particular emphasis on synaptology.


Pilonidal cyst of the anal canal: case report.


Introduction of William SLOAN.

Introduction of William SLOAN.


Rupture of the spleen, and thrombocytopenia, in glandular fever.


The role of grief in psycho-analysis.

The role of grief in psycho-analysis.


Ribosomal aggregate engaged in protein synthesis: characterization of the ergosome.


Electron microscope study on the regenerative process of peripheral nerves of mice.


Self-stimulation aftereffcts and runway performance in the rat.


Retroperitoneal, lumber, and pelvic malignancies simulating the "disc syndrom".


The consumer has the last word.

The consumer has the last word.


The high-frequency sensitivity of the guinea pig ear.


Blood coagulation in arteriosclerotic rats.


Carotid and cerebral arteriosclerosis in the rat.


Effects of a bacterial polysaccharide (Piromen) on the pituitary-adrenal axis: modification of ACTH release by morphine and salicylate.


Spontaneous development of renal calculi in repeatedly bred male and female rats.


Histologic alterations in the adrenal cortex of intact and hypophysectomized rats following ACTH, pitressin and adrenal steroids.


The T-V1 taller than T-V6 pattern. Its potential value in the early recognition of myocardial disease.


Six steps to better hospital purchasing.


Perfusion hypothermia studies in dogs. Cinefluorographic and hemodynamic studies.


Demonstration of the dynamic nature of idiopathic hypertrophic subaortic stenosis.


Hemodynamic effects of isoproterenol infusion in patients with normal and diseased mitral valves.


Suppression of the development of female mating behavior by estrogen administered in infancy. The administration of estradiol benzoate subcutaneously to 4-day-old female rats resulted in reduced mating in response to estrogen and progesterone in adulthood.


Effect of stretch on O2 consumption of resting and active frog sartorius muscle.


Work and oxygen consumption in the frog sartorius muscle.


Respiration of heart muscle as affected by oxygen tension. Isolated cat papillary muscles were exposed to gas mixtures containing carbon dioxide and oxygen. In muscles exposed during the second of three periods to 25 percent oxygen, the volume of oxygen consumed (Q(o2)) was depressed by 50 percent, but returned to the control level during a third period at 98 percent oxygen. The work capacity was not significantly altered if the partial pressure of oxygen was low.


Effect of large variations in external potassium on the oxygen consumption of rat heart strips.


The Golgi apparatus and cell plate formation--a postulate.


Dermatofibrosarcoma protuberans.

Dermatofibrosarcoma protuberans.


Hyperparathyroidism and pregnancy.

Hyperparathyroidism and pregnancy.


Immunological studies of a heterogenetic enterobacterial antigen (Kunin). Whang, H. Y. (Children's Hospital, Buffalo, N.Y.) and E. Neter. Immunological studies of a heterogenetic enterobacterial antigen (Kunin). J. Bacteriol. 84:1245-1250. 1962.-Study of the heterogenetic antigen revealed that it is present in relatively large amounts in supernatant fluids of heat-killed, agar-grown enterobacterial suspensions. The antigen modifies erythrocytes for agglutination by heterogenetic antibodies in Escherichia coli O14 antiserum. Of the highly purified lipopolysaccharides (10 mug/ml) tested, only a Shigella sonnei preparation had significant activity. In the hemagglutination-inhibition test, minimal activity was detected also in lipopoly-saccharides from E. coli O111 and various salmonellase. There was no parallelism in capacity of these lipopolysaccharides to neutralize heterogenetic and homologous O antibodies. The hemolytic modification of the hemagglutination test proved to be from two to eight times more sensitive than the hemagglutination method. Supernatant fluids of unheated agar-grown suspensions contained small amounts of antigen, and boiling of the bacterial suspensions resulted in the release of additional and substantial quantities. Heterogenetic antibodies did not cause agglutination of latex particles treated with heterogenetic antigen, but E. coli O14 antibodies agglutinated latex particles treated with the corresponding O antigen.


Nutritive intake of adolescents. A study in Southern Illinois.


House fly populations and their dispersion in Malaya with particular reference to the fly problem in the Cameron Highlands.


The development of methods for trapping the vectors of monkey malaria.


Adaptation of Wuchereia and Brugia to mosquitoes and vertebrate hosts in relation to the distribution of filarial parasites.


Malaria vector problems in South-East Asia.


The biology of Mansonia mosquitoes in relation to the transmission of filariasis in Malaya.


Energetics of isolated muscle.

Energetics of isolated muscle.


Status, role and vocational continuity of discharged mental patients.


Separation of the light and dark reactions in electron transfer during photosynthesis.


The forward thrust in preventive medicine.


Pamphlets and changes in behaviour: experimental evidence.


Studies on the cell wall of Chromobacterium violaceum: the separation of lipopolysaccharide and mucopeptide by phenol extraction of whole cells.


Characterization of a 4-amino-4:6-dideoxy aldohexose from Chromobacterium violaceum.


An unusual case of acne keloid.

An unusual case of acne keloid.


What the physician can do about preventing accidents to children.


Psychiatric nursing. Patients working for pay.


On some remarkable and hitherto unobserved phenomena of binocular vision.


Role of transferrin in iron absorption.

Role of transferrin in iron absorption.


The use of ethamivan in the treatment of barbiturate poisoning. Ethamivan was used as a respiratory analeptic in the treatment of nine cases of severe barbiturate poisoning. Initial intravenous injections of 100 to 150 mg. of ethamivan increased the depth of respirations within a minute. Prolonged respiratory stimulation was achieved by a continuous intravenous infusion of 500 to 3000 mg. of ethamivan per litre of fluid. If hypotension occurred, an intravenous drip of noradrenaline was used; fluid overloading was avoided by adjusting the concentrations of drugs given, so that no more than a total of 125 c.c. of fluid per hour was administered. The chief side effect of overdosage of ethamivan was muscular twitching. This did not prove to be a problem and was of some value in determining the amount of drug given. The nine patients survived. It was concluded that ethamivan is a useful agent in the treatment of barbiturate poisoning.


Simultaneous determination of glycerol, inositol, serine and ethanolamine in a phospholipid hydrolyzate.


Carisoprodol-prednisolone in the management of arthritis.


Respondeat superior: a dialogue while a someone bleeds.


Expressed wishes of students.

Expressed wishes of students.


A neurophysiologic view of functional disorders. (A contribution to our understanding and management of functional illness).


A new direction for directors?

A new direction for directors?


Acute edema in leprosy.

Acute edema in leprosy.


How we trained intensive care nurses.

How we trained intensive care nurses.


Searches for exploitable biochemical differences between normal and cancer cells. X. Catabolism of purines by regressing tumors.


Use of spleen-slice homografts in the study of graft-versus-host reactions.


Effect of cross-circulation on kidney homograft rejection in dogs.


The General Practitioner Research Group.


The many faces of "pulseless disease".

The many faces of "pulseless disease".


Electrolyte transport and bile formation.


An application of discriminant functions to the problem of predicting brain damage using behavioral variables.


Fome properties of a kidney adenosine triphosphatase relevant to active cation transport.


Discriminant functions applied to the problem of predicting cerebral damage from behavioral tests: a cross-validation study.


Presence and laterality of brain damage predicted from responses to a short aphasia screening test.


Health education in the interagency approach to urban renewal.


Descriptive study of acute gallbladders at the Carney Hospital.


The left aortic diverticulum as a component of a constricting vascular ring. Report of two neonatal cases.


Giant cell carcinoma of thyroid.

Giant cell carcinoma of thyroid.


The application of thin layer chromatography to sulfobromophthalein metabolism studies.


Action of adrenaline on limb blood vessels.


Autonomic transmitter mechanisms.

Autonomic transmitter mechanisms.


Utilization of biuret by Pseudonomas aeruginosa.


A p-n junction photovoltaic detector for use in radiotherapy.


Profile of greatness. A short history of the Radiumhemmet at Stockholm.


Radiation therapy of gynecological malignancies at the I. Universitats-Frauenklinik, Munich, Germany, and at the Radiumhemmet, Stockholm, Sweden.


A fringe benefit hypothermia and its use in a community hospital.


Detection and resolution of gangliosides in lipid extracts by thin-layer chromatography.


Observations on the course of fibrinolysis.


Dermal cylindroma.

Dermal cylindroma.


The Bowie and Dick autoclave tape test.

The Bowie and Dick autoclave tape test.


Idiopathic intussusception in the adult.


Radiation regulations.

Radiation regulations.


Procedure management in clinical enzyme chemistry.


Results of surgical treatment of incipient stroke.


Improved procedures for preparation and characterization of myrothecium cellulase. 2. Purification procedures.


Diagnosis and management of ischemic cerebral vascular disease: a review.


A multiple-column hydraulic method for fractionation of particles for chromatographic columns.


Improved procedures for preparation and characterization of myrothecium cellulase. I. Production of enzyme.


A reminiscence: pancreaticduodenectomy.

A reminiscence: pancreaticduodenectomy.


Focal cellular alteration in stable amnion cells produced by inoculation with human leukemia brain extracts.


Hereditary spherocytosis associated with sickle trait and choliithiasis.


Lead poisoning--a masquerade.

Lead poisoning--a masquerade.


"The right of privacy".

"The right of privacy".


Internal combustion.

Internal combustion.


Some host factors in the development of renal cell carcinoma.


Increased carbon dioxide tension and the primary isolation of Mycobacteria.


Irritable bowel.

Irritable bowel.


Unusual incarcerated groin hernias.

Unusual incarcerated groin hernias.


Alteration of colony morphology of mycobacteria associated with lysogeny. White, Arthur (University of Louisville, Louisville, Ky.), Frances Foster, and Linda Lyon. Alteration of colony morphology of mycobacteria associated with lysogeny. J. Bacteriol. 84:815-818. 1962.-Smooth colonies of mycobacteria were obtained from previously rough strains after exposure to phages R(1) and D-32 in a higher frequency than could be expected from selection of mutants alone. A high proportion of the smooth colonies were lysogenized. Smooth lysogenized strains maintained both lysogeny and smooth morphology after repeated subcultures on agar or in Tween media. The available evidence suggests that lysogeny with certain mycobacteriophages alters colony morphology by a means other than selection of mutants.


Effect of human serum and Tween 80 on several mycobacteriophages and susceptible mycobacteria.


The radiology of intestinal obstruction in Rhodesia.


Scholarship: teaching and research.

Scholarship: teaching and research.


Helping hands for deaf patients.

Helping hands for deaf patients.


The ward unit in a new hospital. What the architect needs to know.


An apparatus for lifted weights and other successively presented stimuli.


Paracervical block anesthesia in obstetrics.


Umbilical cord prolapse and presentation. A study of 62 consecutive cases.


Refrigeration as a preventive measure in food poisoning.


Vaccinia gangrenosa due to hypogammaglobu-linaemia.


Anesthesia and postpartum headache.

Anesthesia and postpartum headache.


Haemadsorption to single cells in suspension.


Useful current cancer chemotherapeutic agents.


Dual block after intermittent suxamethonium.


Cytochromelinked fermentation in Bacteroides ruminicola. White, D. C. (Rockefeller Institute, New York, N.Y.), M. P. Bryant, and D. R. Caldwell. Cytochrome-linked fermentation in Bacteroides ruminicola. J. Bacteriol. 84:822-828. 1962-Previous studies showed that Bacteroides ruminicola, an anaerobic, saccharolytic, ruminal bacterium, ferments glucose with the production of succinic, acetic, and formic acids, requires a large amount of CO(2), and most strains require heme for growth. Difference spectra of cell suspensions of both heme-requiring strain 23, B. ruminicola subsp. ruminicola, and heme-independent strain GA33, B. ruminicola subsp. brevis, showed the presence of a cytochrome (absorption maxima at 560 mmu, near 530 mmu, and 428 mmu) similar to cytochrome b. This cytochrome and flavoprotein (trough at 450 mmu) in the cells, reduced by endogenous metabolism, were oxidized on addition of air, CO(2), oxalacetate, malate, or fumarate but no oxidation occurred in the presence of succinate, malonate, lactate, pyruvate, aspartate, citrate, NO(3) (-), SO(4) (=), 2-n-heptyl or hydroxyquinoline-N-oxide (HOQNO), amytal or azide. The oxidation of these cellular pigments by fumarate was not inhibited by CN(-), CO, malonate, succinate, amytal, or HOQNO. Glucose and reduced diphosphopyridine nucleotide (DPNH), but not succinate, reduced the pigments in frozen-thawed cells previously exposed to air for 4 hr at room temperature. The results suggest that this cytochrome and flavoprotein form an electron transport system for fumarate reduction to succinate by DPNH generated by glycolysis, and that succinate is produced via CO(2) condensation with pyruvate or phosphoenolpyruvate and with oxalacetate, malate, and fumarate as intermediates. A pigment similar to cytochrome o (absorption maxima at 570, 555, and 416 mmu) was observed when reduced cells were treated with CO and compared to reduced cells, but there was no detectable cytochrome oxidase activity. The function of this pigment is obscure. No peroxidase or catalase activity was detected in either strain. Pyridine hemochromogens of both strains indicate one major heme, a protoheme-like pigment, with absorption in the alpha region maximum at 556 mmu. As B. ruminicola is one of the most numerous of rumen bacteria and ferments a wide variety of carbohydrates of importance in ruminant rations, cytochrome must be of importance in electron transport in rumen contents, a highly anaerobic environment.